Mapiritsi a Mertenil: kuwunika kwa madotolo ndi zofunikira kuti agwiritse ntchito

Tsiku labwino. Tsoka ilo, kwa zaka zambiri, thanzi silikula, kenako, kenako wina, kenako kumbuyo, kenako kukakamiza kapena china. Pomwe kukakamira kumayamba, adadutsa mayeso onse ndipo zidapezeka kuti cholesterol ili mkati moyenera, koma adotolo adapereka mankhwala kuti athane ndi cholesterol pamalire kwambiri. Amasiyana, koma pakadali pano ndidayimitsa mankhwala osokoneza bongo a rosuvastatin, poyamba ndidatenga Roxer, koma anali okwera mtengo kwambiri ndipo ndidatenga analogue muchipatala - Mertenil, sindinganene kuti ndiotsika mtengo, komabe. Mankhwalawa adadzaza pabokosi la makatoni, atatu chithuza mapiritsi khumi. Kumangilidwa ndi langwiro lalikulu lokhala ndi pepala lalikulu kuposa A 3, pomwe chilichonse chimafotokozedwa mwatsatanetsatane. Pa mapiritsi pali chizindikiro, ine C 34, chomwe chikufanana ndi 10 milligrams p. kuwerenga kwambiri ozuvastatin. Ndimatenga piritsi limodzi patsiku, madzulo, ngakhale malangizo sakhazikitsa nthawi yovomerezeka. Mankhwala amalekerera mosavuta, palibe mavuto omwe adadziwika. Pankhani yothandiza mankhwalawa, kuchuluka kwa cholesterol kumatha kusungidwa mosadukiza, ngakhale, moona, sinditsatira mosamalitsa chakudyacho ndipo nthawi zina ndimalolera ndekha kuwonjezeka. Chifukwa chake, ndikuganiza kuti kugwiritsa ntchito Mertenil kuli kolondola ngakhale pamtengo wokwera.

Tsiku labwino. Tsoka ilo, kwa zaka zambiri, thanzi silikula, kenako, kenako wina, kenako kumbuyo, kenako kukakamiza kapena china. Pomwe kukakamira kumayamba, adadutsa mayeso onse ndipo zidapezeka kuti cholesterol ili mkati moyenera, koma adotolo adapereka mankhwala kuti athane ndi cholesterol pamalire kwambiri. Amasiyana, koma pakadali pano ndidayimitsa mankhwala osokoneza bongo a rosuvastatin, poyamba ndidatenga Roxer, koma anali okwera mtengo kwambiri ndipo ndidatenga analogue muchipatala - Mertenil, sindinganene kuti ndiotsika mtengo, komabe. Mankhwalawa adadzaza pabokosi la makatoni, atatu chithuza mapiritsi khumi. Kumangilidwa ndi langwiro lalikulu lokhala ndi pepala lalikulu kuposa A 3, pomwe chilichonse chimafotokozedwa mwatsatanetsatane. Pali zilembo pamapiritsi, ine ndili ndi C 34, womwe umafanana ndi kuchuluka kwa mamiligalamu 10 a rosuvastatin. Ndimatenga piritsi limodzi patsiku, madzulo, ngakhale malangizo samapereka nthawi yovomerezeka. Mankhwala amalekerera mosavuta, palibe mavuto omwe adadziwika. Pankhani yothandiza mankhwalawa, kuchuluka kwa cholesterol kumatha kusungidwa mosadukiza, ngakhale, moona, sinditsatira mosamalitsa chakudyacho ndipo nthawi zina ndimalolera ndekha kuwonjezeka. Chifukwa chake, ndikuganiza kuti kugwiritsa ntchito Mertenil kuli kolondola ngakhale pamtengo wokwera.

Mertenil ndi rosuvastatin wochokera ku Europe. Caka ciliconse, mazana a odwala omwe ali ndi matenda am'mtima amandilumikizira. Ndipo pafupifupi munthu aliyense wachiwiri amakhala ndi vuto la metabolidi ya lipid, nthawi zambiri amakhala ndi cholesterol yambiri yamagazi. Kampani yopanga zamankhwala ku Hungary, a George Richter omwe ali ndi mankhwalawa adapanga mankhwala "Mertenil", omwe amapezeka mu Mlingo wambiri wa 5 mg, 10 mg, 20 mg, 40 mg m'mapiritsi 30 (kusowa kwa pamwezi). "Mertenil" adzipangira okha mankhwala osavuta pomusankha, sindinayenere kutsatira. Njira zochizira Mertenil zimathamanga kwambiri, ndipo kale atalandira chithandizo kwa miyezi iwiri kapena itatu, kuchuluka kwa lipid metabolism kunakwaniritsidwa. Ndikupangira mankhwalawa kwa anthu omwe ali ndi matendawa. kuwerenga kwambiri evanesii a mtima dongosolo, amakonda kuchita atherosclerosis, anali akuvutika ndi mtima ndi stroko. Kuphatikiza apo, Mertenil akuwonetsedwa kwa odwala omwe ali ndi matenda obadwa nawo a carbohydrate metabolism. Ndinkakonda kwambiri mankhwala a Mertenil ndipo ndimawalangizabe kwa odwala anga!

Mertenil ndi rosuvastatin wochokera ku Europe. Caka ciliconse, mazana a odwala omwe ali ndi matenda am'mtima amandilumikizira. Ndipo pafupifupi munthu aliyense wachiwiri amakhala ndi vuto la metabolidi ya lipid, nthawi zambiri amakhala ndi cholesterol yambiri yamagazi. Kampani yopanga zamankhwala ku Hungary, a George Richter omwe ali ndi mankhwalawa adapanga mankhwala "Mertenil", omwe amapezeka mu Mlingo wambiri wa 5 mg, 10 mg, 20 mg, 40 mg m'mapiritsi 30 (kusowa kwa pamwezi). "Mertenil" adzipangira okha mankhwala osavuta pomusankha, sindinayenere kutsatira. Njira zochizira Mertenil zimathamanga kwambiri, ndipo kale atalandira chithandizo kwa miyezi iwiri kapena itatu, kuchuluka kwa lipid metabolism kunakwaniritsidwa. Ndimalimbikitsa mankhwalawa kwa anthu omwe ali ndi matenda a mtima, omwe amakonda kutha kwa matenda a mtima, omwe akuvutika ndi matenda a mtima komanso mikwingwirima. Kuphatikiza apo, Mertenil akuwonetsedwa kwa odwala omwe ali ndi matenda obadwa nawo a carbohydrate metabolism. Ndinkakonda kwambiri mankhwala a Mertenil ndipo ndimawalangizabe kwa odwala anga!

Chaka chatha, amayi anga adakumana ndi vuto lalikulu la thanzi. Atamuunika kwathunthu, adotolo adalemba mankhwalawa, kuphatikiza Mertenil. Poyerekeza ndi ena, awa ndi mapiritsi okwera mtengo kwambiri, motero tisanagule, tinaphunzira malangizo mosamala. Malangizowo ali ngati pepala. Ndi yayikulu kwambiri, ndipo mawonekedwe ake ndi ochepa kwambiri. Zimatenga pafupifupi ola limodzi ndi theka kuphunzira ndi kudziwa zinthu zonsezi. Inemwini, ndidayesa kuti mankhwalawa sikuti ndi vuto lililonse, muyenera kumwa kokha monga adokotala adanenera. Pali zovuta zambiri zoyipa. M'mbuyomu, ndidakumana ndi mndandanda wofanana wazotsatira zoyipa pokhapokha pophunzira malangizo a aspirin. Mertenil amagwiritsidwa ntchito kutsitsa cholesterol yamagazi. Komabe, zomwe takumana nazo zawonetsa kuti mapiritsi awa okha ndi otsika. werengani zambiri. Ndi zamanyazi, poganizira mtengo wawo. Kwa miyezi isanu ndi umodzi, amayi anga adawatenga, kenako kudutsa mayeso. Cholesterol yachepa, koma pang'ono pang'ono. Kenako tinalumikiza maphikidwe angapo wowerengeka ku mapiritsi awa, omwe adapangidwa kuti athetse vuto lomweli. Ndipo atatha miyezi 6 anapambananso mayesowo. Nthawi yomweyo, zakudya sizinasinthe, ndiye kuti, mayi adadyanso ndendende zakudya zomwe zinali ngati kale, asanayambe chithandizo. Ndipo pokhapokha adawona zotsatira. Dotoloyo adadabwa momwe tachokera kuti tithetse vutoli. Adasankha kuti amayi anga adye zakudya zokhwima, zomwe zidathandiza kuti zinthu ziziwayendera bwino. Pali contraindication ambiri, mavuto. Koma sitinakumane ndi zotsatila zilizonse. Izi ndizodabwitsa, ndi mndandanda wosangalatsa, komanso wokondwa nthawi yomweyo. Ndondomeko ya kumwa mapiritsiwo imangotulutsidwa ndi adokotala, ngakhale ilinso mu malangizo, koma, monga adokotala anati, ndi pafupifupi. Mapiritsiwo ndi ochepa, amaledzera mosavuta. Chakudya chamadzulo sichisiya. Ndipo osayambitsa chisokonezo chilichonse. Ngati pazifukwa zaumoyo zikufunika, ndiye kuti palibe kupezeka kulikonse. Mwina pali ma fanizo otsika mtengo a iwo, koma sindikuwadziwa. Chifukwa chake, mukadayenera kugula "Mertenil." Ziri zamanyazi zokha kuti pawokha, popanda chithandizo chowonjezera, sizothandiza. Ngakhale maphikidwe a anthu wamba amatitengera ndalama kwaulere, ndikadakonda kukhala ndi phindu lalikulu kuchokera ku mtengo wokwera mtengo chotere.

Chaka chatha, amayi anga adakumana ndi vuto lalikulu la thanzi. Atamuunika kwathunthu, adotolo adalemba mankhwalawa, kuphatikiza Mertenil. Poyerekeza ndi ena, awa ndi mapiritsi okwera mtengo kwambiri, motero tisanagule, tinaphunzira malangizo mosamala. Malangizowo ali ngati pepala. Ndi yayikulu kwambiri, ndipo mawonekedwe ake ndi ochepa kwambiri. Zimatenga pafupifupi ola limodzi ndi theka kuphunzira ndi kudziwa zinthu zonsezi. Inemwini, ndidayesa kuti mankhwalawa sikuti ndi vuto lililonse, muyenera kumwa kokha monga adokotala adanenera. Pali zovuta zambiri. M'mbuyomu, ndidakumana ndi mndandanda wofanana wazotsatira zoyipa pokhapokha pophunzira malangizo a aspirin. Mertenil amagwiritsidwa ntchito kutsitsa cholesterol yamagazi. Komabe, zomwe takumana nazo zawonetsa kuti mapiritsi awa okha ali ndi mphamvu zochepa. Ndi zamanyazi, poganizira mtengo wawo. Kwa miyezi isanu ndi umodzi, amayi anga adawatenga, kenako kudutsa mayeso. Cholesterol yachepa, koma pang'ono pang'ono. Kenako tinalumikiza maphikidwe angapo wowerengeka ku mapiritsi awa, omwe adapangidwa kuti athetse vuto lomweli. Ndipo atatha miyezi 6 anapambananso mayesowo. Nthawi yomweyo, zakudya sizinasinthe, ndiye kuti, mayi adadyanso ndendende zakudya zomwe zinali ngati kale, asanayambe chithandizo. Ndipo pokhapokha adawona zotsatira. Dotoloyo adadabwa momwe tachokera kuti tithetse vutoli. Adasankha kuti amayi anga adye zakudya zokhwima, zomwe zidathandiza kuti zinthu ziziwayendera bwino. Pali contraindication ambiri, mavuto. Koma sitinakumane ndi zotsatila zilizonse. Izi ndizodabwitsa, ndi mndandanda wosangalatsa, komanso wokondwa nthawi yomweyo. Ndondomeko ya kumwa mapiritsiwo imangotulutsidwa ndi adokotala, ngakhale ilinso mu malangizo, koma, monga adokotala anati, ndi pafupifupi. Mapiritsiwo ndi ochepa, osavuta kumwa. Chakudya chamadzulo sichisiya. Ndipo osayambitsa chisokonezo chilichonse. Ngati pazifukwa zaumoyo zikufunika, ndiye kuti palibe kupezeka kulikonse. Mwina pali ma fanizo otsika mtengo a iwo, koma sindikuwadziwa. Chifukwa chake, mukadayenera kugula "Mertenil." Ziri zamanyazi zokha kuti pawokha, popanda chithandizo chowonjezera, sizothandiza. Ngakhale maphikidwe a anthu wamba amatitengera ndalama kwaulere, ndikadakonda kukhala ndi phindu lalikulu kuchokera ku mtengo wokwera mtengo chotere.

Ngati mungathe popanda iwo. Koma ayi. Mtengo wa mapiritsiwo siwung'ono kwambiri ndipo sungatchulidwe kutiwokulira, popeza ndikudziwa kuti mankhwalawa amatha kutaya ndalama zachilendo. Kupitilira ma ruble 700 anapatsidwa paketi ya mapiritsi 30. Mwamuna wanga alinso ndi cholesterol yayikulu. Zikuwoneka kuti kwakanthawi ndidakhala pafupifupi 4 ndi kobiri, koma pano posachedwa adasungidwa. Ndiponso zoposa 7. Ndipo adotolo adatinso mapiritsiwo. Ngati mumvera zomwe abambo akunena, ndiye kuti nthawi zonse ayenera kumwa iwo. Zomwe ndimakhulupirira. Kodi chiwindi chimatha kupirira izi? Kapena kumwa mpaka chiwindi chimagwira? Zakudya m'nyumba mwathu zasintha nthawi yayitali. Chimodzimodzi pambuyo pa opareshoni. Koma zakudya ndi zina mwazinthu zomwe zimakhudza cholesterol. Palinso zizolowezi zoyipa zomwe zimakhudzanso chiwindi ndipo pakadali zaka, malinga ndi zomwe. ndizovuta kuwerenga pano, zomwe zikutanthauza ulesi. Ndipo ngakhale ntchito ya mnzanuyo ikugwirizana ndi kayendedwe, amakhala nthawi yayitali akukhala pakompyuta pa mbeza. Chifukwa chake, timakhala zochepetsera cholesterol yokhala ndi zisonyezo zoposa 7. Tiyenera kumwa mapiritsi patsiku kapena usiku. Kulandilanso komanso kutsimikizira kwazizindikiro kuyambira miyezi itatu. ndipo ndendende miyezi itatu muyenera kumwa Mertenil. Chifukwa kumwa usiku. Dokotala adalongosola kuti chiwindi chimatulutsa - cholesterol usiku. Chifukwa chake, mankhwalawa amatengedwa asanagone. Mankhwala ndi otpit. Cholesterol adatsika ndikulemba 5. Ziwerengezi ziyenera kuyang'aniridwa kuti zitha kupewa nkhani yomwe idachitika kale. Ndalankhula za zotsatirapo za cholesterol yayikulu popenda za chipatala. Izi ndizomwe zimachitika ndi madokotala. Ndikukufunirani thanzi labwino. Thanzi lotere, kotero kuti mpaka zaka 120 ndikokwanira, kapenanso kutalika)

Ngati mungathe popanda iwo. Koma ayi. Mtengo wa mapiritsiwo siwung'ono kwambiri ndipo sungatchulidwe kutiwokulira, popeza ndikudziwa kuti mankhwalawa amatha kutaya ndalama zachilendo. Kupitilira ma ruble 700 anapatsidwa paketi ya mapiritsi 30. Mwamuna wanga alinso ndi cholesterol yayikulu. Zikuwoneka kuti kwakanthawi ndidakhala pafupifupi 4 ndi kobiri, koma pano posachedwa adasungidwa. Ndiponso zoposa 7. Ndipo adotolo adatinso mapiritsiwo. Ngati mumvera zomwe abambo akunena, ndiye kuti nthawi zonse ayenera kumwa iwo. Zomwe ndimakhulupirira. Kodi chiwindi chimatha kupirira izi? Kapena kumwa mpaka chiwindi chimagwira? Zakudya m'nyumba mwathu zasintha nthawi yayitali. Chimodzimodzi pambuyo pa opareshoni. Koma zakudya ndi zina mwazinthu zomwe zimakhudza cholesterol. Palinso zizolowezi zoyipa zomwe zimakhudzanso chiwindi ndipo pakadali zaka, chifukwa chomwe zimakhala zovuta kusuntha, zomwe zikutanthauza ulesi. Ndipo ngakhale ntchito ya mnzanuyo ikugwirizana ndi kayendedwe, amakhala nthawi yayitali akukhala pakompyuta pa mbeza. Chifukwa chake, timakhala zochepetsera cholesterol yokhala ndi zisonyezo zoposa 7. Tiyenera kumwa mapiritsi patsiku kapena usiku. Kulandilanso komanso kutsimikizira kwazizindikiro kuyambira miyezi itatu. ndipo ndendende miyezi itatu muyenera kumwa Mertenil. Chifukwa kumwa usiku. Dokotala adalongosola kuti chiwindi chimatulutsa - cholesterol usiku. Chifukwa chake, mankhwalawa amatengedwa asanagone. Mankhwala ndi otpit. Cholesterol adatsika ndikulemba 5. Ziwerengezi ziyenera kuyang'aniridwa kuti zitha kupewa nkhani yomwe idachitika kale. Ndalankhula za zotsatirapo za cholesterol yayikulu popenda za chipatala. Izi ndizomwe zimachitika ndi madokotala. Ndikukufunirani thanzi labwino. Thanzi lotere, kotero kuti mpaka zaka 120 ndikokwanira, kapenanso kutalika)

Mankhwala amachepetsa cholesterol ndi triglycerides. Izi zisanachitike, adatenga Tricor, koma sanadikirire, koma adangopeza cholesterol yapamwamba kwambiri. Koma atalandilidwa ndi Mertenil, zonse zidasintha.

Mankhwala amachepetsa cholesterol ndi triglycerides. Izi zisanachitike, adatenga Tricor, koma sanadikirire, koma adangopeza cholesterol yapamwamba kwambiri. Koma atalandilidwa ndi Mertenil, zonse zidasintha.

Moni, abwenzi anga ndi owerenga, mutu wanga lero siwosangalatsa kwambiri - zamankhwala. Chaka chilichonse kuntchito, timayesedwa ngati timayesedwa kwambiri. Ndipo ndikadikirira kudabwitsika kosadukiza kwamafuta a cholesterol Popeza zonse zina zinali zachilendo, kuyambira pomwe, adotolo adandilangizira za kadyedwe. Zinali zofunika kuthetsa vuto la zakudya. Ndayiwala mawu oti "poto wokazinga", adapanga menyu woyenera. Zotsatira zake, panali kuwonjezereka kwa mafuta m'thupi. Tsopano aliyense akudziwa zoopsa zomwe manambala akukumana nazo. Zolemba za cholesterol, zomwe zimayikidwa pamakoma amitsempha yamagazi, zimayambitsa kuchepetsedwa kwa lumen. Ndi zotchinga, zitha kuphimba mtsempha wamagazi. Zotsatira zake - matenda a stroke, kugunda kwa mtima. Osatengera chifukwa chomwe chiwonjezere cha cholesterol (cholakwika. Kuwerenga njira yina kapena cholowa) - zotsatira zake zimakhala zomvetsa chisoni, ndipo ndikufuna kuzipewa. Ndipo ndidathamangira kukadwala kwamankhwala kuti ndikhale kunyumba. Zambiri zapaintaneti (mankhwala oletsa cholesterol). Ndinkawopa kuchuluka kwa zoyipa. Koma, tsoka, palibe chomwe adachita: Adandipangira Mertenil, ndi mulingo wa 10 mg. Wopanga: Gedeon Richter (Hungary) .Kulemba mabokosi atatu a mapiritsi 10. Mtengo m'dera la 530 rubles. Tengani kamodzi patsiku, makamaka nthawi imodzi. Ndidapita kunyumba ndikumapita kokatenga nthawi yayitali, chifukwa ndi manambala anga zotsatira sizikhala pomwepo. Koma pofuna kudziwongolera, zinali zofunikirabe kupereka magazi mwezi umodzi. Kodi adokotala adadabwa chiyani pomwe kuwunikaku kunawonetsa chotere? Iwo adaganiza kuti ma labotore ena adalakwitsa. Ndinaleka kumwa mankhwalawa kwakanthawi. Cholesterol yanga yoyipa "idatsitsimukanso." Kenako adaganiza zochepetsa mlingo wa magalamu 5. Mapiritsiwo ndi ochepa. Izi zikufanizidwa ndi omega. Ndimamwa tsiku lililonse. Pambuyo pakuyang'anira miyezi itatu, magawo onse a chiwindi amabwereranso mwakale, ndizotheka kuti pambuyo pake tidzayesanso kuchepetsa mankhwalawa. Inde, musaphwanye mapiritsi pang'onopang'ono, koma ingomwani tsiku lililonse. Pali zovuta zambiri pazokhumudwitsa, monga momwe zilili ndi mankhwala onse.Komabe, kuphatikiza ndi zomwe zimadziwika kale: chizungulire, kudzimbidwa, mseru, palinso zina zowonjezera.Kulimbikitsa kwa matenda amtundu wa II kumakhala koopsa kale .. Asthenic syndrome - kutopa kokwanira, kutopa, kusakhazikika kwa mankhwalawa - kulinso kanthu kabwino. ngati ndi chakanthawi. Kukhala ndi izi mwina ndizovuta Komabe, wopangayo akuwatsimikizira kuti zoyipa zomwe zimadza chifukwa chogwiritsa ntchito Mertenil ndizakanthawi kochepa kapena pang'ono. Nthawi zambiri amadalira kuchuluka kwa mankhwalawa. Chifukwa chake malangizo ogwiritsira ntchito Mertenil amayenera kuyang'aniridwa mosamalitsa .. Zonsezi, ndakhala ndikumwa mankhwalawa kuti ndichepetse mafuta a m'magazi a Mertenil ndi kale mwezi wachisanu ndi chimodzi. Zotsatira zake ndizothandiza kwambiri. Kuwerengera magazi konse ndi kwabwinobwino. Sindinazindikire kuwonongeka kulikonse mukukhazikika. Ndikupangira mankhwalawa kuti agwiritse ntchito.

Moni, abwenzi anga ndi owerenga, mutu wanga lero siwosangalatsa kwambiri - zamankhwala. Chaka chilichonse kuntchito, timayesedwa ngati timayesedwa kwambiri. Ndipo ndikadikirira kudabwitsika kosadukiza kwamafuta a cholesterol Popeza zonse zina zinali zachilendo, kuyambira pomwe, adotolo adandilangizira za kadyedwe. Zinali zofunika kuthetsa vuto la zakudya. Ndayiwala mawu oti "poto wokazinga", adapanga menyu woyenera. Zotsatira zake, panali kuwonjezereka kwa mafuta m'thupi. Tsopano aliyense akudziwa zoopsa zomwe manambala akukumana nazo. Zolemba za cholesterol, zomwe zimayikidwa pamakoma amitsempha yamagazi, zimayambitsa kuchepetsedwa kwa lumen. Ndi zotchinga, zitha kuphimba mtsempha wamagazi. Zotsatira zake - matenda a sitiroko, vuto la mtima. Mosatengera chifukwa chomwe chiwonjezere cha cholesterol (moyo wosayenera kapena cholowa) - zotsatira zake zimakhala zomvetsa chisoni, ndipo ndikufuna kuzipewa. Ndipo ndidathamangira kuofesi ya adotolo kuti ndikamwe mankhwala. (mankhwala ochepetsa mafuta a cholesterol). Ndinkawopa kuchuluka kwa zoyipa. Koma, tsoka, palibe chomwe adachita: Adandipangira Mertenil, ndi mulingo wa 10 mg. Wopanga: Gedeon Richter (Hungary) .Kulemba mabokosi atatu a mapiritsi 10. Mtengo m'dera la 530 rubles. Tengani kamodzi patsiku, makamaka nthawi imodzi. Ndidapita kunyumba ndikumapita kokatenga nthawi yayitali, chifukwa ndi manambala anga zotsatira sizikhala pomwepo. Koma pofuna kudziwongolera, zinali zofunikirabe kupereka magazi mwezi umodzi. Kodi adokotala adadabwa chiyani pomwe kuwunikaku kunawonetsa chotere? Iwo adaganiza kuti ma labotore ena adalakwitsa. Ndinaleka kumwa mankhwalawa kwakanthawi. Cholesterol yanga yoyipa "idatsitsimukanso." Kenako adaganiza zochepetsa mlingo wa magalamu 5. Mapiritsiwo ndi ochepa. Izi zikufanizidwa ndi omega. Ndimamwa tsiku lililonse. Pambuyo pakuyang'anira miyezi itatu, magawo onse a chiwindi amabwereranso mwakale, ndizotheka kuti pambuyo pake tidzayesanso kuchepetsa mankhwalawa. Inde, musaphwanye mapiritsi pang'onopang'ono, koma ingomwani tsiku lililonse. Pali zovuta zambiri pazokhumudwitsa, monga momwe zilili ndi mankhwala onse. Komabe, kuphatikiza ndi zomwe zimadziwika kale: chizungulire, kudzimbidwa, mseru, palinso zina zowonjezera.Kulimbikitsa kwa matenda amtundu wa II kumakhala koopsa kale .. Asthenic syndrome - kutopa kokwanira, kutopa, kusakhazikika kwa mankhwalawa - kulinso kanthu kabwino. ngati ndi chakanthawi. Kukhala ndi izi mwina ndizovuta Komabe, wopangayo akuwatsimikizira kuti zoyipa zomwe zimadza chifukwa chogwiritsa ntchito Mertenil ndizakanthawi kochepa kapena pang'ono. Nthawi zambiri amadalira kuchuluka kwa mankhwalawa. Chifukwa chake malangizo ogwiritsira ntchito Mertenil amayenera kuyang'aniridwa mosamalitsa .. Zonsezi, ndakhala ndikumwa mankhwalawa kuti ndichepetse mafuta a m'magazi a Mertenil ndi kale mwezi wachisanu ndi chimodzi. Zotsatira zake ndizothandiza kwambiri. Kuwerengera magazi konse ndi kwabwinobwino. Sindinazindikire kuwonongeka kulikonse mukukhazikika. Ndikupangira mankhwalawa kuti agwiritse ntchito.

Pharmacodynamics ndi pharmacokinetics

Mapiritsi a Mertenil ndi choletsa chosankha komanso chopikisana pa enzyme yomwe imatembenuza GMG-CoA mu kupitilira. Ikagwiritsidwa ntchito, imakhala ndi tanthauzo lalikulu, momwe imapangira cholesterol ndipo Catabolism wa LDL (mapangidwe otsika lepoproteins). Amakhala ndi mapuloteni a plasma pafupifupi 90%. Kupenda zochepa - 10%.

Calcium ya Rosuvastatin imatsitsa cholesterol yonse ndi LDL cholesterol. Mankhwala amachotsedwa m'thupi mwachilengedwe. Kudziwulutsa kwake mwadongosolo kumawonjezeka molunjika molingana ndi mlingo womwe umamwa.

Yothandiza pochita ndi anthu hypercholesterolemia, ngakhale atakhala kuti ndi amuna kapena akazi komanso zaka.

Pazigawo yambiri yogwira madzi a m'magazi amafikika pafupifupi maola 5 mutamwa mlingo woyenera. Bioavailability pafupifupi 20%.

Mphamvu yoyamba ya kugwiritsa ntchito mankhwalawa imadziwika pambuyo pa sabata. Kusintha kwina kwabwino komwe kumachitika pambuyo pa mwezi 1 wothandizira ndikuwusungidwa ndikugwiritsanso ntchito mankhwalawa.

Zisonyezo Mertenil

Zowonetsa kugwiritsa ntchito Mertenil zitha kukhala izi:

  • hypercholesterolemia,
  • kuphatikiza dyslipidemic zinthu,
  • hypertriglyceridemia Fredrickson Mtundu IV
  • banja homozygous hypercholesterolemia,
  • kupewa ndi kuchiza atherosulinosis,
  • kupewa matenda a mtima (vuto la mtima, ochepa kusintha, sitiroko etc.).

Mankhwalawa nthawi zambiri amawagwiritsa ntchito ngati adjunct zakudya mankhwalapamene zakudya zokha komanso njira zina zothandizira kuchepetsa matenda a lipid, mwachitsanzo, kuchita masewera olimbitsa thupi sikokwanira.

Contraindication

Mertenil mapiritsi a 5, 10 ndi 20 mg osavomerezeka kuti atenge:

  • azimayi oyembekezera
  • nthawi kuyamwa,
  • azimayi amisinkhu yobala ana ogwiritsa ntchito njira zodalirika zolerera,
  • at kulephera kwa chiwindi,
  • mukamagwiritsa ntchito michere ndi cyclosporine,
  • chifukwa chosowa lactase ndi lactose tsankho
  • Ndi zovuta ndi impso,
  • anthu omwe ali ndi vuto latsoka la myotoxic,
  • m'malo mwa myopathies,
  • ndi chidwi chachikulu ndi kusalolera kwa munthu pazinthu zina za mankhwala,
  • m'malo mwa shuga galactose malabsorption.

Mapiritsi a Mertenil a 40 mg ndi oletsedwa kutenga ndi:

  • hypothyroidism,
  • kumwa kwambiri
  • matenda a chiwindi mu gawo yogwira,
  • mbiri yaumwini kapena yabanja yamatenda amisempha.

Mlingo wofananawo simalimbikitsidwa kwa odwala amtundu waku Asia.

Kuphatikiza apo, Mertenil amatchulidwa mosamala mu:

  • zovuta za metabolic, electrolyte ndi endocrine,
  • osalamulirika khunyu,
  • ochepa hypotension,
  • sepsis,
  • chiwopsezo chowonjezereka cha mawonekedwe ndi chitukuko myopathies,
  • mbiri ya matenda a chiwindi,
  • kuvulala
  • kuchitapo kanthu kwakukulu kwa opaleshoni.

Kuphatikiza apo, muyenera kutenga chida ichi mosamalitsa kwa anthu azaka zopitilira 65. Koma magwiridwe ake ndi chitetezo cha ana sichinakhazikitsidwebe.

Zotsatira zoyipa

Zotsatira zoyipa za Mertenil zitha kukhala motere:

Nthawi zina, zitha kuchitika zotupaKhungu myopathy, rhabdomyolysis, kapamba, urticaria. Ndipo kudya pafupipafupi mapiritsi a 40 mg, kukula ndikotheka myalgia, proteinuria ndi myopathies. Kuphatikiza apo, pamtengowu, kuchuluka kwa chidwi kumatha. bilirubin ndi shuga, komanso chithokomiro chodwala.

Kuphatikiza apo, ngati mukutenga Mertenil, malangizo ogwiritsira ntchito akuwonetsa kuti, nthawi zina, zimachitika arthralgia, jaundice, chiwindi, kuiwalika, kupuma movutikirazotumphukira edema, kutsegula m'mimba, hematuria, polyneuropathy, kutsokomola.

Komabe, zoyipa zomwe zimadza chifukwa chogwiritsa ntchito Mertenil nthawi zambiri zimakhala zazifupi kapena zochepa. Nthawi zambiri, zimadalira kuchuluka kwa mankhwalawa. Chifukwa chake malangizo a Mertenil ayenera kuyang'aniridwa mosamala.

Kwa ululu wamisempha wosayembekezeka kapena kuyamba kwake kufooka kwa minofulimodzi ndi general malaise ndi malungosiyani kumwa mankhwalawo mwachangu ndi kukaonana ndi dokotala.

Malangizo ogwiritsira ntchito Mertenil

Mutha kumwa mankhwalawa nthawi iliyonse yamkati ndi madzi ochepa. Komabe, kudya kwake kuyenera kuphatikizidwa ndi chakudya chomwe chinavomerezedwa ndi katswiri. Zakudya za tsiku ndi tsiku zizikhala ndi zakudya zamafuta ochepa.

Munthawi zonsezi, mlingo wa mankhwala kwa wodwala umasankhidwa payekha. Choyamba, zimatengera cholinga cha mankhwalawa. Mukamasintha mlingo, kuchuluka kwa cholesterol kwa wodwala aliyense kumatchulidwa, komanso kuopsa kwa zovuta zamtima ndi zotsatira zoyipa.

Mlingo wocheperako nthawi zambiri umakhala wa 5-10 mg patsiku. Pang'onopang'ono (koma osati kale kuposa mwezi) mlingo umatha kuchuluka. Mapiritsi a 40 mg amatengedwa bwino kuyang'aniridwa ndi dokotala.

Kuchita

Mertenil ndikofunikira kwambiri kuphatikiza molondola ndi mankhwala ena. Ngati mukuvomereza:

  • Cyclosporin - Mertenil AUC (dera lomwe lili pansi pajikanthawi yovuta») Kuchulukitsa kasanu ndi kawiri.
  • Ezetimibe - kusintha kwa AUC ndi kuchuluka kwa mankhwalawa. Kuopsa kwa zochitika zovuta.
  • Mapuloteni oletsa - Kukulitsa kwamachitidwe a Mertenil ndikotheka.
  • Erythromycin - kuchepa kwa AUC0 - t ndi Cmax Mertenyl.
  • Otsutsa vitamini K - kuwonjezeka kwa INR (maubale apadziko lonse lapansi) ndikotheka.
  • Gemfibrozil ndi mankhwala ena otsitsa a lipid - kuwirikiza kawiri mu ndende ndi AUC ya Mertenil. Pali chiopsezo cha myopathy. Kugwiritsa ntchito pamodzi kwa mapiritsi a Mertenil a 40 mg ndi fibrate ndi oletsedwa. Mlingo rosuvastatin sayenera kukhala apamwamba kuposa 5 mg.
  • Maantacid - paz kuyimitsidwa komwe kuli zotayidwa kapena magnesium hydroxide, ikhoza kupangitsa kuchepa kwa kuchuluka kwa Mertenil m'magazi am'magazi ndi theka.
  • Kulera kwamlomo ndi m`malo mankhwala - kuwonjezeka kotheka ku AUC ethinyl estradiol 26% ndi chindapusa ndi 34%.
  • Isoenzymes cytochrome P450 - Kuwonjezeka pang'ono kwa AUC ya Mertenil ndikotheka.

Analogs a Mertenil

Ma analogi a Mertenil, zida, PBX code ndi mawonekedwe omwe amatulutsidwa:

  • Klivas 10, Klivas 20,
  • Crestor,
  • Sintha,
  • Rosart,
  • Rosator,
  • Rosuvastatin Sandoz,
  • Rosucard 10,Rosucard 20,Rosucard 40,
  • Rosulip,
  • Roxer,
  • Romazik,
  • Mofulumira.

Zonse zimagulitsidwa pamapiritsi okhala ndi filimu. Mtengo wa mapiritsi 10 mg umachokera ku 65 mpaka 150 UAH.

Mtengo wa Mertenil analogues molingana ndi code ya ATC ya 4th pa avareji kuchokera pa 40 mpaka 80 UAH.

Ndemanga za Mertenil

Ndemanga za Mertenil ndizabwino. Monga lamulo, sizimayambitsa mavuto. Zabwino zonse za odwala omwe amamwa mapiritsi cholesterolsizimakulirakulira.

Akatswiri akukambirananso ngati kugwiritsa ntchito ma statins kuli koyenera komanso kuti kuchuluka kwa mankhwalawa kuyenera kukhala kotani.

Mtengo wa Mertenil, komwe mungagule

Chida ichi ndi chokhacho chomwe chili ku rosuvastatin ku Russia wokhala ndi mitundu yonse. Kutengera mlingo womwe waperekedwa, mtengo wa Mertenil udzakhala wosiyana.

Mtengo wa Mertenil 10 mg ku Ukraine uli pa 10,000 UAH, ndipo ku Russia - 700 rubles. Mtengo wa mapiritsi okhala ndi mitundu yayikulu imakhala pa 240 UAH. ku Ukraine ndi ruble 1100-1400. ku Russia.

Zizindikiro zogwiritsidwa ntchito

Kodi chimathandiza ndi chiyani Mertenil? Mapiritsi amalembedwa kwa odwala omwe ali ndi zotsatirazi zamatumbo:

  • Mafuta akulu mtima,
  • Herederal hypercholesterolemia,
  • Hypertriglyceridemia monga gawo la zovuta mankhwala molumikizana ndi zakudya,
  • Chiwopsezo chachikulu cha ma atherosulinotic amana pamakoma amitsempha yamagazi akuluakulu,
  • Kupewera kwa chitukuko cha matenda a mtima mu mtima ndi odwala omwe ali ndi kunenepa kwambiri, matenda oopsa, matenda oopsa aposachedwa kapena vuto la mtima,
  • Hypertriglyceridemia (mtundu IV malinga ndi Fredrickson) monga chowonjezera pa chakudyacho.
  • Odwala opitilira zaka 60, amenenso ali ndi vuto lolemera.

Malangizo ogwiritsira ntchito Mlingo wa Mertenil

Ndikofunikira kutsatira zakudya ndikugwiritsira ntchito zakudya zamafuta ochepa musanayambe Mertenil. Ngati malamulo azakudya sakutsatiridwa, chithandizo chamankhwala chimachepetsedwa kwambiri, kotero zakudya ziyenera kuchitika nthawi yonse ya chithandizo. Mlingo wa mankhwalawa amasankhidwa mosiyanasiyana malinga ndi cholinga cha mankhwalawo komanso njira yothandizira wodwalayo, poganizira zomwe alipo omwe akuvomerezedwa kuti azigwirizana ndi milingo ya lipid.

Mapiritsi a Mertenil amatengedwa pakamwa, ngakhale chakudya, chamezedwa chonse ndikutsukidwa ndi madzi. Mlingo woyambira wabwino ndi 5 mg kapena 10 mg kamodzi patsiku. Mukamasankha koyamba mlingo, muyenera kuganizira kuchuluka kwa cholesterol, chiopsezo cha zovuta zamtima komanso chiopsezo cha zovuta zina mwa wodwala aliyense. Ngati ndi kotheka, kusintha kwa mlingo mutha kuchitika pambuyo pa masabata anayi.

Pambuyo pa mwezi pamwezi wa muyeso wochepera, malinga ndi zotsatira za mayeso a labotale, dokotala amatha kusiya mlingo osasinthika kapena kuchuluka, molingana ndi zomwe zikuwonetsa.

Mlingo pa 40 mg / tsiku. Amalembedwa pokhapokha ngati mwadzidzidzi, ochepa mphamvu ya m'munsi Mlingo, komanso odwala kwambiri hypercholesterolemia ndi chiopsezo chotenga matenda a mtima.

Analogs Mertenil, mndandanda wa mankhwala

Mankhwalawa ndi genos wa rosuvastatin, chifukwa mankhwalawa ndi mawonekedwe amodzimodzi a Mertenil pazomwe zimagwira, mndandanda:

Chofunikira - Malangizo a Mertenil ogwiritsira ntchito, mtengo ndi kuwunika sizigwira ntchito pa analogues ndipo sangagwiritsidwe ntchito ngati chiwongolero chogwiritsira ntchito mankhwala omwe ali ndi kapangidwe kake. Nthawi zonse zochizira ziyenera kupangidwa ndi dokotala. Mukasintha Mertenil ndi analogue, ndikofunikira kufunsa katswiri, mungafunike kusintha njira zamankhwala, mankhwalawa, etc. Osadziletsa!

Kuthana bwino kwa machitidwe a hypercholesterolemic kumatheka pokhapokha ndi njira yolumikizirana - chakudya chamafuta ndi mafuta ochepa komanso mchere, zolimbitsa thupi ndikumwa mankhwala omwe adokotala adawalimbikitsa.

Mertenil: malangizo ogwiritsira ntchito

Zotsatira za pharmacologicalMertenil, monga mankhwala ena a rosuvastatin, amachepetsa cholesterol "yoyipayo" ya LDL m'magazi, kwinaku akuletsa kapangidwe kake m'chiwindi. Kweza cholesterol "yabwino" ya HDL. Amachepetsa kutupa m'matumbo. Amasintha C-yogwira mapuloteni komanso zofunikira zina za kutupa. Zotsatira za kuyesedwa kwa magazi zimayamba kuyenda bwino pambuyo pa masabata 1-2, mphamvu yayikulu - pambuyo pa masabata 2-4.
PharmacokineticsMertenil ndi mapiritsi ena a rosuvastatin amatha kumwa ndi chakudya kapena pamimba yopanda kanthu, mphamvu ya izi sizisintha. Rosuvastatin wachotsedwa m'thupi ndi 90% ndi chiwindi kudzera m'matumbo, ndi 10% - ndi impso. Ndi yocheperako kuposa ma statin ena, imadzaza machitidwe a chiwindi, omwe amathandizira kuyeretsa magazi a zinthu zomwe zimagwiritsidwa ntchito ndi mankhwala. Chifukwa cha izi, amatha kuyanjana pang'ono ndi mankhwala ena kuposa maumbidwe akale.
Zizindikiro zogwiritsidwa ntchitoKukwezedwa cholesterol mwa akulu ndi achinyamata. Kuletsa kukula kwa atherosulinosis. Kupewa matenda oyamba ndi kubwereza kwa mtima, ischemic stroke ndi zovuta zina za atherosulinosis. Pambuyo pa opaleshoni kuti mubwezeretse magazi mu ziwiya zomwe zimakhudzidwa ndi atherosulinosis. Kuchulukitsa kwa C-yogwira protein m'magazi pakakhala zinthu zina zomwe zingayambitse matenda ena, ngakhale cholesterol ndiyabwino.Kutenga mapiritsi a Mertenil sikulowa m'malo mwa moyo wathanzi. Werengani nkhani ya mutu wakuti “kupewa matenda a mtima ndi sitiroko” ndikuchita zomwe ukunena. Kupanda kutero, mankhwalawa athandizira pang'ono.

Onaninso vidiyo:

MlingoYambani ndi kuchuluka kwa 5 kapena 10 mg patsiku. Pambuyo pa masabata anayi, mlingo wa mapiritsi utha kuchulukitsidwa, malinga ndi momwe kuchuluka kwa cholesterol m'magazi kwasinthira panthawiyi komanso momwe wodwalayo amalolera chithandizo. Phunzirani cholesterol ya amuna ndi akazi pazaka. Nthawi zambiri, odwala amatenga rosuvastatin 10-20 mg patsiku. Mulingo waukulu wa 40 mg umaperekedwa makamaka kwa anthu omwe cholesterol yake ndiyokwera kwambiri chifukwa cha majini. Mertenil amatchulidwa muyezo Mlingo wa okalamba, komanso odwala omwe ali ndi vuto lowonda laimpso kapena kwa chiwindi.
Zotsatira zoyipaMertenil, monga ma statin ena, amatha kupweteketsa minofu, kufooka, kutopa, kukumbukira ndikuganiza, kukwiya, komanso kugaya chakudya. Onani nkhani "Zotsatira za ma statins" - pezani momwe mungachepetse zizindikiro zosasangalatsa kapena kuzichotseratu. Kukonzekera kwa Rosuvastatin kuli ndi zovuta zina zapadera. Werengani zambiri momwe rosuvastatin amatetezeka. Kwa anthu omwe ali ndi chiopsezo chachikulu cha matenda a mtima komanso sitiroko, ma statin amachita zabwino zambiri kuposa kuvulaza. Ziyenera kuchotsedwa pokhapokha ngati zotsatirapo zake sizingalephereke ndipo sizitha. Kuopsa kwa mavuto a chiwindi ndi kukokomeza. Osadandaula za iwo ngati simumamwa mowa kwambiri.
ContraindicationMatenda a chiwindi mu gawo yogwira. Kuwonjezeka kwakukulu kwa michere ya chiwindi ALT ndi AST m'magazi. Zowopsa zaimpso - kulengedwa kwa creatinine kosakwana 30 ml / min. Hypersensitivity to rosuvastatin kapena zinthu zina zomwe zimapanga mapiritsi. M'mayiko olankhula Chirasha, zaka zosakwana 18 zimawonedwa ngati zachinyengo, ngakhale kuti zakunja, kukonzekera kwa rosuvastatin ndi komwe achinyamata amakonzekera kuyambira zaka 10.
Mimba komanso KuyamwitsaMertenil, mankhwala ena a rosuvastatin ndi ma statin ena onse amakhala ndi pakati pa mimba. Amayi azaka zoyambira kubereka omwe amathandizidwa ndi ma statins ayenera kugwiritsa ntchito njira zodalirika zolerera. Ngati mimba yosakonzekera yachitika, ndiye kuti kumwa mapiritsi a cholesterol kuyenera kuyimitsidwa nthawi yomweyo. Potengera momwe mankhwalawo amathandizira ndi mankhwalawa, simungathe kuyamwitsa.
Kuyanjana kwa mankhwala osokoneza bongoMankhwala a Rosuvastatin amapereka mayanjano ocheperako ndi mankhwala ena kuposa mibadwo yam'mbuyomu mibadwo. Komabe, ngozi yayikulu idakalipo. Pangakhale mavuto ndi maantibayotiki, ma modifera okhala ndi chitetezo chamthupi, mapiritsi othandizira kubereka, magazi ochepa mphamvu, komanso mankhwala ena ambiri. Izi zimatha kuyambitsa mavuto akulu - chiwindi ndi impso. Lankhulani ndi dokotala wanu! Musanalandire Mertenil, uzani dokotala za mankhwala onse, zowonjezera zakudya, komanso zitsamba zomwe mukumwa.
BongoPalibe chithandizo chamankhwala osokoneza bongo a mapiritsi a rosuvastatin. Madokotala amatipatsa chithandizo chamankhwala komanso chothandizira, kuwunika ntchito ya chiwindi komanso kuchuluka kwa ntchito ya creatinine phosphokinase. Hemodialysis sichithandiza kuchotsa rosuvastatin m'thupi.
Malangizo apaderaKuyambira kuthandizidwa ndi Mertenil, pitilizani kutsatira zakudya ndikumakhala ndi moyo wathanzi. Ndikulimbikitsidwa kuyang'anira ntchito ya impso pogwiritsa ntchito magazi ndi mkodzo. Ngati mapuloteni amapezeka mumkodzo kapena kuchuluka kwake kumawonjezeka, yang'anani kwa dokotala. Ngati mukusowa mahomoni a chithokomiro, ndiye kuti musathamangire kutenga ma protein, koma samalani hypothyroidism kuti mubwezeretse cholesterol. Kukonzekera kwa Rosuvastatin kumawonjezera shuga m'magazi mwa odwala matenda ashuga komanso prediabetes.
Kutulutsa Fomu5 mg, 10, 20 ndi 40 mg mapiritsi okhala ndi mafilimu. Mu matuza a zojambulazo mapiritsi 10. Mu phukusi la makatoni 3 ma contour cell phukusi.
Migwirizano ndi magwiritsidwe akusungidwaSungani pamalo owuma, amdima, osatheka ndi ana, pamtunda wosaposa 30 ° C. Moyo wa alumali ndi zaka zitatu.
KupangaZomwe zimagwira ndi calcium wa rosuvastatin. Zabwino - lactose monohydrate, magnesium hydroxide, crospovidone (mtundu A), magnesium stearate. Chipolopolo cha piritsi ndi talc, macrogol, titanium dioxide (E171), mowa wa polyvinyl.

Odwala ambiri ali ndi chidwi ndi zomwe fanizo la Mertenil limatsika mtengo. Pali mankhwala ambiri otere mu pharmacy. Amapangidwa ku Russia Federation ndi mayiko a CIS, komanso ochokera ku Europe ndi Asia. Awa ndi magome pomwe amagwira ntchito ndi rosuvastatin. Onerani kanema wokhudza malo omwe Mertenil angagwiritsidwe ntchito, kuti musalakwitse posankha.

Kumbukirani kuti Mertenil ndiosakanikirana pamtengo wokwera komanso wabwino ku Europe. Ngati ikuthandizani ndipo mumalekerera kugwiritsidwa ntchito kwake, sizingakhale zomveka kuti musinthane ndi analogues kuti musunge ndalama. Zingakhale bwino kutenga Krestor, rosuvastatin woyambayo. Komabe, zimawononga zochulukirapo.

Mertenil: ndemanga

Werengani ndemanga za anthu omwe amatenga Mertenil pano. Amakambirana momwe mankhwalawa amakhudzira thanzi komanso chiwindi. Chithandizo chogwira mankhwalawa ndi rosuvastatin - chida chothandiza kwambiri chomwe chimatsitsa cholesterol "yoyipa" ya LDL m'magazi. Kwa odwala ena, ngakhale mankhwala amphamvuwa samathandiza mokwanira. Dziwani zifukwa zomwe Mertenil sangakhale ndi chidwi kwambiri ndi cholesterol, komanso zoyenera kuchita pankhani zotere.

Anthu omwe ali ndi zidziwitso zenizeni zogwiritsira ntchito mapiritsi a rosuvastatin ayenera kumwa mankhwalawa tsiku lililonse, popanda kusokoneza. Musadabwe ndi ndemanga zoyipa zomwe otsala ena adasiya. Mavuto amabwera mwa iwo omwe amamwa Mertenil molakwika komanso m'maganizo amadzikhazikitsa, akuyembekeza pasadakhale kuti mankhwalawa adzayambitsa mavuto. Kwa anthu ambiri, rosuvastatin amathandiza bwino popanda kudwalitsa. Koma odwala okhutira samakonda kuvutitsa zolemba pamankhwala azachipatala.

Mawonekedwe ndi kipimo

Mertenil ndi mankhwala a hypolipidemic. Zotsatira zake za mankhwala ndi kuponderezana kwa HMG-CoA reductase. Chida chimenecho ndi cha gulu la ma statins, chinthu chogwira ntchito ndi rosuvastatin. Mankhwalawa amaloledwa ndi kampani yopanga mankhwala ku Hungary, ndipo dziko lopanga ndi Russian Federation.

Mapiritsi a Mertenil ali ndi mlingo wa 5, 10, 20 ndi 40 mg wa rosuvastatin. Kuphatikiza pazomwe zimagwira, mawonekedwe ake akuphatikizanso zina:

  • ma cellulose makhristali amodzi,
  • monohydrogenated lactose,
  • magnesium hydroxide ndiwotoni.

Mankhwalawa amawaika m'maselo a pulasitiki okhala ndi mapiritsi 10, 30, 60 kapena 90 pamakatoni. Zoyenera kugawa kuchokera ku malo ogulitsa mankhwala - malinga ndi mankhwala olembedwa mchilatini mogwirizana ndi malamulo akwaniritsidwe.

Pharmacokinetics of Mertenil: metabolism ya Rosuvastatin imachitika mu hepatocytes mothandizidwa ndi ma molekyulu angapo olondola. Wogawika mawonekedwe, 90% ya mankhwalawa amachotsedwa m'thupi ndi ndowe. Mlingo wotsalawo umachoka m'thupi kudzera mu impso.

Zotsatira zoyipa

Mertenil amaloledwa bwino ndi odwala. Pa mankhwala ndi mankhwala, zosafunikira zimawonedwa. Malinga ndi kafukufuku, ndi 4% yokha ya anthu omwe amamwa mankhwalawa omwe ali ndi mavuto. Zotsatira zosafunikira za mankhwalawa zimaphatikizira: chiwonetsero cha matendawa (urticaria, edema ya Quincke, anaphylactic mantha), kuchepa kwa kuchuluka kwa mapuloteni ozungulira, cephalgia, kusowa kwa tulo, pancreatitis yogwira, hepatitis, zizindikiro za dyspeptic, kuwonjezeka kwa ntchito ya michere ya chiwindi.

Kutenga Mertenil kumawonjezera chiopsezo cha myasthenia gravis, rhabdomyolysis, ndi kulephera kwa impso. Zotsatira zoyipa izi nthawi zambiri zimayamba kupezeka mwa anthu omwe amamwa mankhwala a 40 mg patsiku kwa nthawi yayitali.

Mlingo ndi makonzedwe

Masabata angapo musanamwe mankhwalawa, muyenera kutsatira zakudya zoyenera zomwe zili ndi mafuta ochepa a nyama. Pa chithandizo, muyenera kupitilirabe kudya potsatira zomwezo.

Mlingo wa rosuvastatin amasankhidwa payekha. Zimatengera cholinga cha mankhwala, momwe wodwalayo amagwiritsira ntchito mankhwalawo, poyambira kokwanira komanso ndende yoyenera ya plasma cholesterol ndi zigawo zake. Yoyambira mlingo wa 5 mpaka 10 mg wa rosuvastatin patsiku. Mlingo wapamwamba wa tsiku lililonse wa 40 mg wa rosuvastatin amalembera hypercholesterolemia, yomwe ndi yovuta kuilongosola. Chifukwa cha chiwopsezo chachikulu cha mavuto, odwala otere ayenera kulandira chithandizo moyang'aniridwa ndi akatswiri azachipatala. Mankhwala osokoneza bongo amatha kuchitika ngati mulingo wa mankhwala omwe dokotala sanakuwonetse.

Ndikofunikira kumwa mapiritsi athunthu ndi kapu ya madzi oyera. Rosuvastatin amatengedwa kamodzi patsiku, makamaka nthawi imodzi. Mertenil amatha kuledzera asanadye kapena atatha kudya.

Pa mimba ndi mkaka wa m`mawere

Ndikunyamula mwana ndikudyetsa mkaka wa m'mawere, rosuvastatin imatsutsana. Izi ndichifukwa chakufunika kwambiri kwa cholesterol m'magazi a amayi kuti akule bwino kwa mwana wosabadwayo. Mimba ikachitika, chithandizo cha rosuvastatin chimatha nthawi yomweyo. Palibe chodalirika pakuwongolera kwa mankhwalawa chinsinsi cha zofunikira za mabere am'mimba, kotero kuti kuyamwa kumayimitsidwa kwa nthawi yayitali.

Chifukwa cha kusowa kwa chidziwitso chazachipatala chotsimikizira chitetezo ndi ntchito ya rosuvastatin mwa anthu osakwana zaka zambiri, mankhwalawa sangagwiritsidwe ntchito pafupipafupi machitidwe a ana.

Kugwiritsa Ntchito

Odwala omwe adapangidwa ndi Mertenil ndi madokotala nthawi zina amayamba kukayika ngati samatenga mapiritsi omwe adayikidwa. Kuti muthane ndi vutoli, ndibwino kuti muphunzire ndemanga za odwala omwe akutenga Mertenil. Ndemanga zambiri zamankhwala ndizabwino. Anthu omwe adachilandira, amawona kulekerera kwake, zotsatira zake mwachangu. Nanga ndi chiani chomwe chimapangitsa kuti mankhwalawa atchuke? Kuchokera pamtengo wake. Odwala omwe amathandizidwa ndi rosuvastatin amakhutira ndi kuchuluka kwa mtengo wake komanso kugwira ntchito kwawo. Malingaliro a akatswiri a mtima okhudzana ndi mankhwalawa ndi osagwirizana - ndi mankhwala othandiza pamtengo wokwanira, chifukwa nthawi zambiri amauza odwala awo.

Kufotokozera kwamankhwala

Hypolipidymic mankhwala adapangidwa makamaka kupewa ndi kuchiza matenda a atherosulinosis. Ichi ndi mpikisano wosankha wa HMG-CoA reductase, womwe umakhudza chiwindi, umathandiza kuchotsa cholesterol m'thupi, womwe umathandizira kupewa komanso kupewa kutulutsa kwa atherosclerosis.

Katundu waulimi:

  1. 90% yazomwe zimagwira m'mapuloteni a plasma,
  2. Mapiritsiwo ali ndi kulolerana kwabwino, kuchitapo kanthu mwachangu,
  3. The ndende kwambiri m'magazi a zosakaniza woyamba amafika 4-5 pambuyo kumwa,
  4. The bioavailability wa rosuvastatin pafupifupi 20%,
  5. Kufotokozera za kagayidwe - chiwindi,
  6. Imapukusidwa ndi 95% mwa njira yamatumbo, yonse imatuluka ndi mkodzo.

Mankhwala othandiza amaganiziridwa kwa anthu omwe ali ndi hypercholesterolemia omwe ali ndi / popanda zizindikiro za hypertriglyceridemia, komanso amagwiritsidwa ntchito pochiza matenda osokoneza bongo. Zimatsimikiziridwa kuti mu 80% ya odwala omwe amatenga Mertenil pa mlingo wa 10 mg, cholesterol yomwe akutsata idakwaniritsidwa.

Mertenil mogwirizana ndi malangizo angagwiritsidwe ntchito amawaganizira ngati mankhwala omwe amafotokozedwamo kangapo. Katswiri wokhazikitsa mankhwala, kusankha kosavomerezeka kuti atenge statin ndikosayenera: kukulira kwa vutoli ndikotheka, etc.

Statin amalembera omwe amapezeka:

  • Mafuta ambiri mafuta m'thupi - hypercholesterolemia,
  • Machitidwe ochita kuperewera kwa hypercholesterolemia,
  • Hypertriglyceridemia (monga gawo la chithandizo chokwanira ndi zakudya),
  • Chiwopsezo chachikulu cha zovuta za atherosulinotic pamakoma a mitsempha,
  • Hypertriglyceridemia malinga ndi Fredrickson (mtundu IV).

Mertenil amatumizidwanso monga mankhwala othandizira anthu omwe ali ndi kunenepa kwambiri, matenda oopsa, komanso kwa odwala omwe ali ndi nthenda ya mtima posachedwa. Amathanso kutumiza mankhwala kwa odwala azaka zopitilira 60+.

Momwe mungatengere Mertenil: malangizo

Ndikofunika kwambiri kuti wodwala azitsatira zakudya zapadera za hypocholesterol asanayambe kulandira chithandizo. Popanda izi, mankhwalawa atapangidwa ndi mankhwalawa sangapangitse kuti athandize (kapena m'malo mwake, adzachepetsedwa). Zakudyazi ziyenera kuchitika osangomwa mapiritsi, komanso nthawi yonse ya njira zochizira. Ndipo ndikwabwino kuiwona mopitilira, kupangitsa chakudya kukhala chakudya choyenera.

Amamwa mankhwalawo moyenera, samamangidwa pakudya. Mapiritsi ayenera kumezedwa lonse: osathyola kapena kutafuna. Mlingo woyambirira ukhale 5 mg ndi 10 mg (monga adokotala adasankhira!). Popereka mankhwala oyambira, dokotalayo amaganizira kuchuluka kwa mafuta m'thupi, amawunika kuwopsa kwa cardiopathologies, ndikuwunika kuopsa kwa mankhwalawa. Kusintha kwa Mlingo, ngati kuli kotheka, kumachitika patatha pafupifupi milungu inayi kuyambira chiyambi cha chithandizo.

Pambuyo pakulandila kwa mwezi umodzi, wodwalayo, monga lamulo, amatumizidwa kukayezetsa matenda a labotale - pamaziko a zotsatira zawo, dokotala wopezekayo amasintha chithandizocho kapena amauza wodwalayo kuti apitilizabe chithandizo malinga ndi chiwembu chomwecho.

Za mulingo wokwanira, 40 mg, kotero, imayikidwa pokhapokha ngati mankhwala ochepa sanawonetsere kulondola. Komanso, mlingo woterewu ungathe kutumizidwa kwa odwala omwe ali ndi vuto lalikulu la hypercholesterolemia, komanso chiopsezo chowonjezeka cha matenda a mtima ndi mitsempha ya magazi. Mutha kudzikweza nokha!

Ndani sayenera kumwa mankhwalawo

Muzipatala, Mertenil sagwiritsidwa ntchito - palibe umboni wotsimikiza wa chitetezo cha mankhwalawa kwa ana. Popeza mankhwalawa sagwiritsidwa ntchito ndi amayi apakati komanso amayi panthawi ya chiwindi B. Musalimbikitse kumwa Mertenil kwa amayi omwe sakayikira za kudalirika kwa kulera kwawo.

Contraindations akuphatikiza:

  1. Kudziwikiratu kudziwika pangozi ya mbiri yanga,
  2. Myopathy
  3. Kulephera kwa chiwindi
  4. Hypersensitivity pazinthu zilizonse za formula (zonse zomwe zimagwira ndi zina zake),
  5. Lactose kusalolera ndi kuperewera kwa lactase,
  6. Zowopsa zaimpso.

Osatipatsa mankhwala ophatikizira ndi cyclosporine ndi nitrate. Pa mlingo waukulu (40 mg), Mertenil sangathe kutengedwa motsutsana ndi hepatopathology mu exacerbation, motsutsana ndi maziko a hypothyroidism. Mowa waukulu umagwirizananso ndi mankhwalawa. Ngati vuto la minofu ilipo mu mbiri yaumwini kapena banja, adokotala sangakane kupatsa mankhwala a Mertenil.

Ngati bongo umachitika

Pafupifupi nthawi zonse, mankhwala osokoneza bongo amakhudzana ndi kuwonjezeka kwa zotsatira zoyipa za mankhwalawa. Ngati kulibe, koma ngati kuchuluka kwawonjezera, akuwoneka, dokotala. Ngati bongo wambiri ndi zovuta, ndiye kuti wodwala amafunika chithandizo. Palibe chithandizo chamankhwala. Madokotala azidzayang'anira ntchito ya chiwindi, kuwunika zizindikilo zofunika. Hemodialysis sikugwira ntchito.

Zotsatira zoyipa

Mwambiri, nthawi yayifupi. Ziwerengero zimawonetsa 4% yokha mwa odwala omwe alemba zovuta pamankhwala.

Zina mwazotsatira zoyipa ndi izi:

  • Thupi lawo siligwirizana chifukwa cha chotupa pakhungu, osati kuyabwa;
  • Asthenic syndrome, chizungulire pafupipafupi, zilonda m'malo osakhalitsa,
  • Myalgia wamisala yosiyanasiyana,
  • Matenda am'mimba, mseru pang'ono,
  • Pancreatitis

Mwa odwala ena, kupuma movutikira kumawonekera pakumwa mankhwalawo, amazindikira kupuma movutikira. Akaphatikizidwa ndi mankhwala ena, dokotalayo amayenera kuwunika mayendedwe abwino / oyipa. Wodwala yekha sayenera kuletsa adokotala kuti amwe (makamaka ngati amamwa mankhwala omwe amupatsa mankhwala mosagwirizana).

Ngati muli ndi minofu kupweteka, kufooka kwa minofu yachilendo, miyendo yofananira, mphamvu m'manja sikumvetseka, ndikofunikira kusiya kumwa Mertenil. Ndipo zitatha izi, muyenera kufunsa dokotala nthawi yomweyo.

Zomwe mankhwala amaphatikiza amafunika kusamala

Ngati wodwala amupatsa gemfibrozil, ndiye kuti simuyenera kumwa Mertenil limodzi ndi iye. Chowonadi ndi chakuti woyamba mankhwala omwe akuwonetsedwa ndi fibrate. Ziphuphu ndizomwe zimachokera ku fibric acid. Amalembedwanso hypertriglyceridemia, komanso chenjezo la kapamba. Popeza onse ma fibrate ndi ma statin ali ndi zotere, kuphatikiza kwawo kumakhala kofupika ndi kuchepa kowopsa kwa cholesterol, kamenekanso kodzala ndi ngozi.

Ngati Mertenil atengedwa limodzi ndi cyclosporine, ndiye kuti mu zovuta ziwiri zomwezo zimatsogolera kuti statin AUC ikukula nthawi zambiri. Erythromycin amachepetsa mphamvu ya rosuvastatin. Maantacid okhala oyimitsidwa amachepetsa zomwe zili rosuvastatin m'thupi.

Mertenyl ndi fanizo

Ngati wodwalayo ali ndi vuto losagwirizana ndi kumwa Mertenil, ndiye kuti chithandizo chake chimayenera kusintha. Itha kukhala njira yofananira, nthawi zina mndandanda wathunthu.

Mutha kusintha mankhwalawo ndi Acorta, Simvastol, Ariescor, Atomax. Tiyenera kudziwa kuti kwa odwala ambiri, mtengo wa mankhwalawo ndi wofunikira. Chifukwa chake Mertenil ali ndi mtengo wa ma ruble 500, pamtengo womwewo ndi Akorta. Chosakaniza chophatikizira ndi chimodzimodzi - rosuvastatin. Koma mtengo wa Simvastol ndi wotsika kwambiri - pafupifupi ma ruble 60 (chinthu chogwira ntchito ndi simvastatin).

Zambiri pa Hypocholesterol Zakudya

Monga tafotokozera pamwambapa, ngati wodwala satsatira chakudyachi, ngakhale mitengo yotsika mtengo kwambiri siyingakupatseni chithandizo chofunikira. Zakudya za hypocholesterol zimakhazikitsidwa patebulo la chakudya No. 10. Muzochita zamankhwala, gome ili nthawi zambiri limawonetsedwa kwa odwala oopsa, anthu omwe ali ndi cardiopathologies, rheumatism, matenda amkati wamanjenje, etc. Dokotalayo ayenera kudziwitsa wodwalayo nthawi yake komanso momwe angayambitsire chakudyacho. Fotokozani, dongosolo, fotokozerani zonse.

Zogulitsa ndi kuphatikiza kwake zomwe zimasankhidwa muzakudya izi ndizoyenera kuchiza komanso kupewa mtima waschemia, kukonza ndi kupewa matenda a mtima, atherosulinosis. Chakudya chimawonetsedwa kwa anthu omwe akumana ndi zovuta zam'matumbo - kugunda kwa mtima komanso sitiroko.

Mfundo zoyambirira za chakudya chamafuta:

  1. Kuchepetsa kwakukulu kwa kudya kwamchere,
  2. Kuchepa kwa kuchuluka kwa madzimadzi tsiku ndi tsiku,
  3. Zogulitsa zimabwereketsa kuphika pang'ono - zimakonda kuwira, kuphika, kuwotcha,
  4. Mankhwala osavomerezeka, kuchuluka kwa chakudya - mpaka 6,
  5. Chosiyana ndi zakudya ndi mbale zomwe zimakhala ndi mafuta ochulukirapo.

Poyang'ana koyamba, zikuwoneka kuti chakudya sichikhala chochepa, chosasangalatsa, koma sichoncho ayi. Ngati wodwala akutsimikiza zatsopano, awerengera za zakudya zake, azizolowera mwachangu, ndipo izi zikhala maziko abwino azakudya (popanda kusweka).

Tiyeni tiwone zitsanzo: mkaka yaying'ono mafuta, tchizi tchizi, yogati ndi kefir yokhala ndi madzi ochepa, koma simungathe kumwa mkaka wamafuta, mkaka wokhala ndi mkaka. Kirimu tchizi ndi ayisikilimu alinso pamndandanda wazakudya zosafunikira. Zakudya za nsomba ndi nsomba zina zam'madzi ndizovomerezeka, koma nsomba zokazinga komanso zamafuta, shrimp ndi squid sizoyenera kudya. Masamba, zipatso ndi mtedza - ndizotheka, kupatula mbatata yokazinga, zipatso ndi zipatso mu shuga ndi madzi, ma pistachios, ma hazelnuts ndi mtedza nawonso samayikidwa.

Mutha kudya supu zamasamba, msuzi wachiwiri msuzi wa nyama. Koma msuzi puree pa msuzi wamafuta ndi oletsedwa. Simungathe kukana zonunkhira zachilengedwe zosiyanasiyana, ngakhale nthawi zambiri zimakhala zosayenera kugwiritsa ntchito. Koma mayonesi, msuzi wamafuta - izi ndizoletsedwa chakudya. Msuzi wa soya ndiwotheka, koma ochepa komanso osafunikira tsiku lililonse.

Kusiya Ndemanga Yanu