Ryzodeg® FlexTouch® (RYZODEG ® FlexTouch ®)

Makampani ogulitsa mankhwala samayima - chaka chilichonse amapereka mankhwala ochulukirapo komanso ovomerezeka.

Insulin si yosiyana ndi izi - pali mitundu yatsopano ya mahomoni, omwe amapangidwira kuti moyo ukhale wosavuta kwa odwala matenda a shuga, omwe chaka chilichonse amakhala ochulukirachulukira.

Chimodzi mwazomwe zachitika masiku ano ndi insulin Raizodeg kuchokera ku kampani Novo Nordisk (Denmark).

Makhalidwe ndi kapangidwe ka insulin

Ryzodeg ndi insulin wa nthawi yayitali. Ndiwisi wopanda mafuta.

Inapezedwa ndi ma genetic engineering mwa kusintha molekyulu ya DNA ya anthu omwe amagwiritsa ntchito yisiti ya Saccharomyces cerevisiae.

M'mapangidwe ake ma insulin awiri adaphatikizidwa: Degludec - wokhala ndi nthawi yayitali komanso Aspart - wayifupi, muyezo wa 70/30 pa 100 magawo.

Mu 1 unit ya insulin Ryzodeg muli 0,0256 mg Degludek ndi 0,105 mg Aspart. Cholembera chimodzi cha syringe (Raizodeg Flex Touch) chili ndi 3 ml ya yankho, motero magawo 300.

Kuphatikizika kwapadera kwamagulu awiri okhudzana ndi insulini kunapereka chidziwitso chabwino kwambiri cha hypoglycemic, posakhalitsa makonzedwe ndikupanga maola 24.

Makina a kuchitapo kanthu ndi kuphatikiza kwa mankhwala omwe amaperekedwa ndi odwala ndi insulin zolandilira. Chifukwa chake, mankhwalawa amakwaniritsidwa ndipo zotsatira zachilengedwe za hypoglycemic zimatheka.

Basal Degludec amapanga ma microcamera - ma deposti ena m'dera lochepa. Kuchoka pamenepo, insulin kwa nthawi yayitali imasunthira pansi ndipo osalepheretsa zotsatira zake ndipo sasokoneza kuyamwa kwaifupi Aspart insulin.

Insulin Rysodeg, mogwirizana ndi kuti amalimbikitsa kutsika kwa shuga m'magazi, imalepheretsa glycogen kutuluka kwa chiwindi.

Malangizo ogwiritsira ntchito

Mankhwala Ryzodeg amangoyambika mwa mafuta ochulukirapo. Sitha kubayidwa kudzera m'mitsempha kapena kudzera m'mitsempha.

Amakonda kuti jakisoni apangidwe m'mimba, ntchafu, nthawi zambiri m'mapewa. Ndikofunikira kusintha malo a jekeseni molingana ndi malamulo apakati oyambira algorithm.

Ngati jakisoni ikuchitika ndi Ryzodeg Flex Touch (cholembera), ndiye kuti muyenera kutsatira malamulowo:

1. Onetsetsani kuti ziwalo zonse zili m'malo omwe 3 ml cartridge ali ndi 300 IU / ml ya mankhwalawa.
2. Onani ngati singano zotayika NovoFayn kapena NovoTvist (kutalika 8 mm).
3. Mukachotsa chipewa, yang'anani yankho. Ziyenera kukhala zowonekera.
4. Khazikitsani mlingo wofunikira pa cholembera ndikusintha chosankha.
5. Kukanikiza pa "kuyamba", gwiritsitsani mpaka dontho la yankho litatuluke kumapeto kwa singano.
6. Pambuyo pa jekeseni, wogwirizira wa mankhwalawo amayenera kukhala 0. Chotsani ndi singano pambuyo masekondi 10.

Makatoni amagwiritsidwa ntchito kupangira “zolembera”. Zovomerezeka kwambiri ndi Ryzodeg Penfill.

Rysodeg Flex Kukhudza - cholembera chosinthanso. Onetsetsani kuti mwatenga singano zatsopano pa jakisoni aliyense.

Imapezeka pamalonda. Flexpen ndi syringe yotayika yolemba ndi penfill (cartridge).

Risodeg imalembedwa kwa odwala omwe ali ndi matenda amtundu wa 1 komanso a 2. Amasankhidwa kamodzi pa tsiku musanadye chakudya chachikulu. Nthawi yomweyo, insulin yochepa imayendetsedwa musanadye.

Syringe cholembera kanema pophunzitsa:

Mlingo amawerengedwa ndikuwonetsetsa kuchuluka kwa shuga m'magazi a wodwala. Amawerengeredwa aliyense payekha kwa wodwala aliyense ndi endocrinologist.

Pambuyo pa makonzedwe, insulin imatengedwa mwachangu - kuyambira mphindi 15 mpaka ola limodzi.

Mankhwala alibe contraindication matenda a impso ndi chiwindi.

Sitikulimbikitsidwa kugwiritsa ntchito:

• ana ochepera zaka 18
• pa mimba
• uku mukuyamwa
• ndi kuchuluka kwa chidwi cha munthu payekha.

Zofanizira zazikulu za Ryzodeg ndi ma insulini ena omwe akhala akuchita kwa nthawi yayitali. Mukasintha Ryzodeg ndi mankhwalawa, nthawi zambiri sasintha ngakhale mlingo.

Mwa izi, zotchuka kwambiri:

Mutha kuzifanizira mogwirizana ndi tebulo:

Ndikofunikira kuganizira malingaliro pa kayendetsedwe ka Tujeo: ndibwino komanso mosamala kuyang'ana momwe cholembera cha SoloStar chingwe sichitha, popeza kuti kusapeza bwino kungayambitse kuchuluka kopanda tanthauzo. Komanso, kufuula kwake mwachangu kunakhala chifukwa cha kuwonekera kwa malingaliro angapo oyipa pamabungwe.

Mtengo wa mankhwala

Ndikulimbikitsidwa kuti ambiri omwe amapatsidwa insulin pochiza matenda a shuga 1 ndi a Ryzodegum.

Mtundu wa 2 odwala matenda ashuga omwe ali ndi mlingo wa inshuwaransi ya Ryzodeg ayenera kuperekedwa tsiku lililonse.

Pali ndemanga zambiri zabwino zokhudzana ndi kugwiritsa ntchito mankhwalawa - ndizotchuka kwambiri, ngakhale kuti kugula mankhwala mumafakitare sikophweka.

Mtengo udzatengera mtundu wa kumasulidwa.

Mtengo wa Ryzodeg Penfill - katiriji kapu yama 300-unit 3 ml iliyonse imachokera ku 6594, 8150 mpaka 9050 ngakhalenso ruble 13000.

Raizodeg FlexTouch - cholembera cha syringe 100 IU / ml mu 3 ml, Ayi. 5 phukusi, mutha kugula kuchokera ku 7070 mpaka 8737 rubles.

Ndikofunikira kukumbukira kuti m'malo osiyanasiyana komanso mitengo yazamankhwala payokha idzasiyana.

Gulu la Nosological (ICD-10)

Kuphatikizika ndi katundu

Ryzodeg ndi m'badwo watsopano wa basal insulin womwe ungagwiritsidwe ntchito bwino pochiza matenda a shuga a mtundu woyamba wa 2. Kupadera kwa Rysodegum kuli poti nthawi imodzi imakhala ndi insuludart yodziwikiratu komanso yochepa kwambiri ya insuludec.

Ma insulini onse omwe amagwiritsidwa ntchito popanga kukonzekera kwa Ryzodeg ndi fanizo la insulin yaumunthu. Amapezeka ndi makina obwereza omwe amagwiritsa ntchito DNA pogwiritsa ntchito yisiti ya genus Saccharomyces cerevisiae.

Chifukwa cha izi, zimamangirira mosavuta ku cholandilira cha insulin yawo yaumunthu ndipo, pakulumikizana nawo, zimathandizira kuyamwa kwa shuga. Chifukwa chake, Ryzodegum imagwira ntchito monga ambulensi amkati.

Ryzodeg imakhudzanso kawiri: kumbali imodzi, imathandiza ziwalo zamkati mwathupi kuti zithetse bwino shuga kuchokera m'magazi, ndipo inayo, imachepetsa kwambiri kupanga kwa glycogen kudzera m'maselo a chiwindi. Izi zimapangitsa Ryzodeg kukhala imodzi mwa insulin yofunika kwambiri.

Insulin degludec, yomwe ndi imodzi mwazomwe akukonzekera Ryzodeg, ali ndi zochita zina zazitali. Pambuyo pakuyambitsa minofu yaying'ono, imalowa pang'onopang'ono komanso mosalekeza m'magazi, zomwe zimathandiza wodwalayo kupewa magazi ochulukirapo kuposa kuchuluka kwake.

Chifukwa chake, Ryzodeg ali ndi kutchulidwa kwa hypoglycemic, ngakhale kuphatikiza kwa degludec ndi aspart. Izi ziwiri zomwe zimawoneka kuti ndizosagwirizana ndi insulin mu mankhwalawa zimapangitsa kuphatikiza kwakukulu komwe insulin siyimalimbana ndi kuyamwa kwakanthawi.

Kuchita kwa aspart kumayamba pokhapokha jakisoni wa Ryzodegum. Amalowetsedwa m'magazi a wodwalayo ndipo amathandizira kutsitsa shuga m'magazi.

Kupitilira apo, degludec imayamba kukhudza thupi la wodwalayo, lomwe limakamizidwa pang'onopang'ono ndipo limakwaniritsa kwathunthu kufunika kwa wodwala insulin ya maola 24.

Kutulutsa Fomu

Mankhwala amapezeka mu mawonekedwe a yankho lomveka bwino la makonzedwe a intradermal. Njira yothetsera vutoli imayikidwa mu cartridge yamagalasi, yomwe ndi gawo la cholembera cha syxtinge ya Flextach. Ndi chithandizo chake, munthu amatha kukhazikitsa mlingo kuchokera 1 mpaka 80 mayunitsi. Cholemba chimodzi chapadera chimakhala ndi 3 ml (1 ml / 100 PIECES) yothetsera. Phukusi limodzi mumakhala ma syringes asanu.

Tcherani khutu! Ndizoletsedwa kudzazitsa katoni "Rysodeg". Musanagwiritse ntchito mankhwalawa, muyenera kuphunzira malamulo mosamala ndi syringe yapadera.

Pharmacodynamics ndi pharmacokinetics

Zamankhwala a Ryzodeg ndizofananira kwathunthu kwa insulin. Pambuyo pa makonzedwe, degludec insulin imapanga zomwe zimatchedwa ma multihexamers, omwe amalilola kuti liperekedwe pang'onopang'ono kwa nthawi yayitali. Insulin aspart imayamba kugwira ntchito pasanathe mphindi 10 mpaka 20, potero kuthetsa kufunikira kwa insulin. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimamangilira ma insulin receptor, pambuyo pake zimachulukitsa kugwiritsidwa ntchito kwa shuga ndikuchepetsa kuchuluka kwa kupanga kwa shuga ndi chiwindi.

Pambuyo pa utsogoleri, ma multihexamers ochokera ku superulin insulin amayamba kupanga. Kutulutsa pang'onopang'ono kwa mankhwala m'magazi kumatheka chifukwa chotulutsidwa kwa ziphuphu za monlopec. Njira zodutsa sizimalepheretsa kuti aspart azilowetsedwa mwachangu m'magazi atangolowa jakisoni. Chifukwa chake, ndizotheka kukwaniritsa zotsatira zophatikizika.

Hafu ya moyo wa zosakaniza ndi pafupifupi 25 maola. Mtengo umatengera muyeso wa mayamwidwe a degludec. Mlingo wa mankhwalawa sukusokoneza nthawi.

Zizindikiro ndi contraindication

Chizindikiro chokha chogwiritsa ntchito Ryzodeg ndi matenda amtundu woyamba kapena wachiwiri. Zina mwazinthu zotsutsana zomwe zimagwiritsidwa ntchito, pali:

• kusalolera kwa chimodzi mwa zigawo za mankhwala,
• Mimba ndi kuyamwa
• ana ochepera zaka 18.

Kulephera kugwiritsa ntchito mankhwalawa muubwana kapena nthawi yapakati komanso mkaka wa m'mawere kumachitika chifukwa chakuti palibe mayesero azachipatala m'gululi la anthu. Komabe, kafukufuku wazinyama awonetsa kuti degludec ikhoza kukhalapo mkaka wa m'mawere. Musanagwiritse ntchito Ryzodeg, kuyezetsa kuyenera kuchitidwa kuti muwonongedwe.

Zotsatira zoyipa

Kugwiritsa ntchito molakwika mankhwalawa kumatha kuyambitsa mavuto ambiri. Zina mwazinthu zomwe zimadziwika kwambiri ndi izi:

• achina,
• zotupa pakhungu jakisoni,
• lipodystrophy.

Nthawi zina, munthu amatha kudwala matenda owopsa.

Hypoglycemia ndi imodzi mwazotsatira zoyipa zikagwiritsidwa ntchito. Zimayimira kuchepa kwa kuchuluka kwa shuga m'magazi. Zotsatira zoyipa izi zimachitika chifukwa cha mlingo wosankhidwa bwino. Vutoli limadziwika ndi chizungulire, kuloza thupi, kutsekeka kwa khungu, kusawona bwino komanso thukuta lozizira. Hematomas, kutupa, kuyabwa ndi kuwonda zimachitika pamalo a jekeseni. Monga lamulo, mawonetseredwe awa amazimiririka paokha ndipo siziwopseza.

Zofunika! Zotsatira zoyipa zikachitika, munthu ayenera kufunafuna thandizo kwa dokotala. Wodwala aliyense yemwe ali ndi matenda ashuga ayenera kudziwa momwe angachitire pakakhala vuto la hypoglycemia.

Mlingo ndi bongo

Mlingo umasankhidwa payekha. Monga lamulo, jakisoni amachitidwa katatu patsiku musanadye zakudya zazikulu. Mankhwala, kusintha kwa mlingo kumachitika chifukwa cha shuga. Malinga ndi malangizo aboma, malingaliro otsatirawa ndi osiyana:

• ndi mtundu wa 2 shuga, muyeso woyamba wa tsiku lililonse ndi magawo 10,
• ndi matenda amtundu wa 1 shuga, mlingo wa "Ryzodeg" umatengera kugwiritsa ntchito mankhwala ena a insulin,
• nthawi ya jekeseni imatsimikiziridwa ndi chakudya chachikulu ndipo zimatha kusiyanasiyana.

Pazida zonse zakupereka mankhwala, singano yatsopano iyenera kugwiritsidwa ntchito. Sanaphatikizidwe mu phukusi, chifukwa chake liyenera kugulidwa payokha. Nthawi yoyamba kugwiritsa ntchito insulin "Raizodeg" makamaka imayang'aniridwa ndi dokotala kapena namwino. Mutha kudziwa momwe mungapangire jakisoni mu kanema paulalo:

Ndi mankhwala osokoneza bongo, hypoglycemia imachitika. Ndikofunika kudziwa kuti munthu aliyense amawonetsa mitundu yambiri ya mankhwala osiyanasiyana. Ngati shuga yamagazi yatsika pang'ono, ndiye kuti vutoli litha kuthetsedwa mwaokha - muyenera kugwiritsa ntchito mankhwala omwe ali ndi shuga. Muzovuta kwambiri, kulandira zipatala ndikofunikira.

Kuchita

Mankhwalawa amalumikizana ndi magulu otsatirawa a mankhwala:

• othandizira a hypoglycemic
• ACE zoletsa
• glucocorticosteroids,
• Zinthu zokhala ndi testosterone
• Mao zoletsa
• mahomoni a chithokomiro.

Amatha kuwonjezera kapena kuchepetsa kufunika kwa insulin. Pogwiritsa ntchito nthawi imodzi ndi "Ryzodeg" kusintha kwa mankhwalawa mudzafunika kwakukulu kapena pang'ono.

Pamodzi ndi mankhwalawa, njira zina zoletsa matenda a shuga zitha kugwiritsidwa ntchito. Endocrinologist ayenera kupanga njira yochizira poganizira momwe mankhwalawa amathandizira aliyense.

Ndikofunika kudziwa kuti mowa umatha kusokoneza mankhwala. Zakudya zake ziyenera kuyang'aniridwa ngati matenda a shuga alipo. Dokotala ayenera kuganiziranso zamankhwala omwe munthu amagwiritsa ntchito kuti asankhe mlingo woyenera.

Palibe chifukwa chomwe mungasakanizire yankho ndi mankhwala ena kuti mukwaniritse makonzedwe ena. Ngati dotolo apanga regimen yothandizira kuti athane ndi matenda enaake, muyenera kumudziwitsa kuti "Raizodeg" ikugwiritsidwa ntchito.

Pakati pazofanizira kwathunthu kwa mankhwalawa, Penzoill yekha, yemwe amaperekedwa ndi Novo Nordinsk, ndi amene amadziwika.

Mwa njira zina zomwe sizinakwaniritse.

Kupeza chinthu chofanana ndi chilichonse ku Russia chomwe chitha kugwiritsa ntchito limodzi mwachangu komanso mwapadera pazinthu za insulin ndizovuta.

Maganizo a anthu omwe amagwiritsa ntchito mankhwalawa pochiza matenda ashuga:

Ndasintha Ryzodeg posachedwa. Mwa zabwino za insulin iyi ndikufuna kuwunikira zotsatira zazitali komanso zovuta zake. Syringe ndi yosavuta kugwiritsa ntchito. Kukula kwa mlingo kumawonekera bwino, ngakhale kuti sindili ndi maso abwino kwambiri.

Tatyana, wazaka 54

Ndimaona Ryzodeg imodzi yamtundu wa insulin womwe umakonda kwambiri. Chojambula chokha ndicho mtengo. Ndakhala ndikugwiritsa ntchito kwa nthawi yayitali. Sipanakhalepo zoyipa zilizonse.

Mothandizidwa ndi Ryzodeg, ndinatha kuyimitsa matenda amtundu wa 2 matenda ashuga. Kugwiritsa ntchito cholembera kuti mupeze jakisoni wa tsiku ndi tsiku sikovuta. Panopa ndimagwiritsa ntchito pafupifupi maola 24 aliwonse.

Mtengo wa mankhwala umasiyanasiyana kuchokera ku 90000 mpaka 8500 rubles. Ndikofunika kugula mankhwala pokhapokha ngati tili ndi zilolezo zovomerezeka. Pambuyo pakugula, muyenera kuyang'ana mosamalitsa malonda ake. Ngati madzi omwe ali mu cartridge samagwirizana ndi malangizo, ndiye kuti mankhwalawo ndi oletsedwa.

Pomaliza

"Rysodeg" Flextach ndi mankhwala othandiza kwambiri omwe angagwiritsidwe ntchito pa matenda ashuga ngati gawo la zovuta kapena monotherapy. Ndiosavuta kuyendetsa yankho chifukwa cha syringe yapadera. Pachitetezo, munthu ayenera kugwiritsa ntchito singano zatsopano ndi jakisoni iliyonse. Ndikofunikanso kukaonana ndi dokotala pafupipafupi kuti muwone kuyenera kwa mankhwalawa. Ngati zonse zili mu dongosolo, ndiye kuti insulin imagwiritsidwa ntchito mwachilingo.

Zambiri pazomwe madokotala atakulemberani mankhwala a insulin muvidiyo:

Pharmacokinetics

Mafuta Pambuyo pa jekeseni wa sc, mapangidwe a soluble khola la insuludec insulin multihexamers amapezeka, omwe amapanga insulin depot mu subcutaneous adipose minofu, ndipo osasokoneza kutulutsidwa msanga kwa insulin aspart monomers mu bedi lamitsempha.

Multihexamers pang'onopang'ono amadzisiyanitsa, ndikumasokoneza maukodifine a insludec, zomwe zimapangitsa kuti magazi azilowa pang'onopang'ono m'magazi. C_ss gawo la superlong kanthu (insulin degludec) m'magazi amapezeka patatha masiku 2-3 atayang'anira kukonzekera kwa Ryzodeg ®.

Zizindikiro zodziwika bwino za kuyamwa mwachangu kwa insulin aspart zimasungidwa mu Risedeg ®. Mbiri ya pharmacokinetic ya insulin aspart imawonekera mphindi 14 pambuyo pa jekeseni, C_max anati pambuyo mphindi 72

Kugawa. Kuyanjana kwa insludec insulin ya serum albin kumafanana ndi kuchuluka kwa mapuloteni a plasma> 99% m'madzi am'magazi a anthu. Kwa insulin aspart, mphamvu ya plasma yomangira imakhala yotsika (T_1/2 Ryzodeg ® pambuyo pa jekeseni wa s / c amatsimikiza ndi kuchuluka kwa mayamwidwe kuchokera kumisempha yokhala ndi subcutaneous. T_1/2 Degludec insulin pafupifupi maola 25 ndipo mlingo wodziimira pawokha.

Chotsogola. Zotsatira zonse za Ryzodeg ® ndizofanana ndi mlingo wa chigawo chapansi (insulin degludec) ndi gawo la prandial (insulin aspart) mwa odwala omwe ali ndi matenda amtundu 1 ndi 2.

Magulu apadera a odwala

PauloPalibe kusiyana komwe kunapezeka mu pharmacokinetic katundu wa Ryzodeg ® kutengera mtundu wa odwala.

Okalamba okalamba, odwala mafuko osiyanasiyana, odwala omwe ali ndi vuto laimpso kapena kwa chiwindi. Panalibe kusiyana kwakukulu pama pharmacokinetics a Ryzodeg ® pakati pa odwala okalamba ndi achinyamata, odwala amitundu yosiyanasiyana, odwala aimpso ndi hepatic ntchito, komanso odwala athanzi.

Ana ndi achinyamata. Mankhwala a pharmacokinetic a mankhwala a Risedeg ® mu kuphunzira kwa ana (6 - 11 wazaka) ndi achinyamata (12-18 wazaka) wokhala ndi mtundu 1 wa matenda osokoneza bongo amafanana ndi omwe ali ndi odwala akulu omwe ali ndi jakisoni imodzi. Chiwerengero chonse ndi C_max insulin aspart imakhala yofunikira kwambiri kwa ana kuposa akuluakulu komanso chimodzimodzi kwa achinyamata ndi achikulire. Mankhwala a pharmacokinetic a degludec insulin mwa ana ndi achinyamata omwe ali ndi matenda amtundu wa 1 amafanana ndi omwe ali ndi odwala akuluakulu.

Poyerekeza ndi jekeseni imodzi yamadzi a shuga a insludec odwala omwe ali ndi matenda a shuga 1, zimawonetsedwa kuti kuchuluka kwa mankhwalawa kwa ana ndi achinyamata ndiokwera kuposa kumene kwa anthu akuluakulu.

Preclinical Safe Study Data

Zambiri zam'mbuyo zokhudzana ndi maphunziro a chitetezo chamatsenga, kuwopsa kwa Mlingo wobwereza, kuchuluka kwazowopsa, zotsatira zakupha pakubala sizinawonetse vuto lililonse kwa anthu. Chiwerengero cha metabolic ndi mitogenic zochita za insludec insulin ndi chofanana ndi cha insulin ya anthu.

Contraindication

kuchuluka kwa chidwi cha munthu pazinthu zothandizira kapena chilichonse chothandiza cha mankhwalawo.

nthawi yoyamwitsa,

ana osakwana zaka 18 (palibe chochitika chachipatala ndi kugwiritsa ntchito mankhwalawa kwa ana, azimayi panthawi yoyembekezera komanso yoyamwitsa).

Mimba komanso kuyamwa

Kugwiritsa ntchito mankhwala Risedeg ® FlexTouch ® pa nthawi ya pakati kumatsutsana, chifukwa palibe zovuta zamankhwala ndi momwe zimagwiritsidwira ntchito panthawi yapakati. Kafukufuku wokhudzana ndi kubereka mu nyama sikunawonetse kusiyana pakati pa insludec insulin ndi insulin yaumunthu molingana ndi embryotoxicity ndi teratogenicity.

Kugwiritsa ntchito mankhwala Ryzodeg ® FlexTouch ® nthawi yoyamwitsa kumayesedwa, chifukwa palibe zochitika zamankhwala ndi akazi opaka mkaka.

Kafukufuku wazinyama adawonetsa kuti mu makoswe, degludec insulin imachotsedwa mkaka wa m'mawere, ndipo kuchuluka kwa mankhwala mkaka wa m'mawere kumatsika kuposa plasma yamagazi. Sizikudziwika ngati insulin degludec imachotsedwa mkaka wa amayi.

Chonde. Kafukufuku wazinyama sanapeze zovuta za degludec insulin pa chonde.

Mlingo ndi makonzedwe

S / c 1 kapena 2 pa tsiku musanadye kaye. Ngati ndi kotheka, odwala ali ndi mwayi wosintha mosagwiritsa ntchito mankhwala, koma amayenera kumangirizidwa ku chakudya chachikulu.

Ryzodeg ® FlexTouch ® ndi kuphatikiza kwa mankhwala osungunuka a insulle - insuludec insulin wa nthawi yayitali komanso wofulumira. Odwala omwe ali ndi matenda a shuga a mtundu wa 2, Ryzodeg ® FlexTouch ® angagwiritsidwe ntchito ngati monotherapy, kaphatikizidwe ndi PHGP kapena bolus insulin. Odwala omwe ali ndi vuto la matenda ashuga a mtundu woyamba 1 amalembedwa kuti Risodeg ® FlexTouch ® kuphatikiza ndi insulin yochepa / yayikulu yochepa asanadye nawo.

Mlingo wa Ryzodeg ® FlexTouch ® umatsimikiziridwa payekha malinga ndi zosowa za wodwala. Kuti muwonetsetsetsetsetse kutsitsika kwa glycemic, tikulimbikitsidwa kusintha mlingo wa mankhwalawa chifukwa cha kusala kwa plasma glucose.

Monga momwe amakonzera insulin iliyonse, kusintha kwa mankhwalawa kungafunikire ngati wodwalayo azolimbitsa thupi, zakudya zake zomwe zimasintha, kapena matenda ena.

Mlingo woyambirira wa Ryzodeg ® FlexTouch ®

Odwala omwe ali ndi matenda a shuga a 2. Mlingo woyenera wa tsiku ndi tsiku wa Ryzodeg ® FlexTouch ® ndi magawo 10 omwe amatsatiridwa ndikusankhidwa kwa munthu.

Odwala omwe ali ndi matenda a shuga 1. Mlingo woyambira wa Ryzodeg ® FlexTouch ® ndi 60-70% ya zonse zofunika tsiku lililonse. Mankhwala Ryzodeg ® FlexTouch ® amamuikira kamodzi patsiku chakudya chachikulu limodzi ndi insulin yofulumira / yochepa, yoyendetsedwa musanadye zakudya zina, kenako ndikusankha mtundu wa mankhwalawa.

Chotsani kuchokera kukonzekera kwina kwa insulin

Kuyang'anira mosamala kuchuluka kwa shuga m'magazi mukusamutsidwa komanso mu milungu yoyamba yopanga mankhwala atsopano ndikulimbikitsidwa. Malangizo a concomitant hypoglycemic therapy (muyezo ndi nthawi ya makonzedwe apafupifupi ndi a ultrashort insulin kapena mlingo wa PHGP angafunike.

Odwala omwe ali ndi matenda a shuga a 2. Mukasamutsa odwala omwe amalandila insulin kapena biphasic insulin Therapy kamodzi patsiku, muyezo wa Ryzodeg ® FlexTouch ® uyenera kuwerengedwa pamtundu wa unit kuchokera paliponse la insulin yomwe wodwala amalandira asanasamuke ku mtundu watsopano wa insulin. Mukasamutsa odwala omwe ali ndi njira yopitilira muyeso umodzi wa basal kapena biphasic insulin, mlingo wa Ryzodeg ® FlexTouch ® uyenera kuwerengedwa payokha-yunifolomu, ndikusamutsira kumakonzedwe a Ryzodeg ® FlexTouch ® muyezo womwewo wa insulin, zomwe wodwalayo adalandira asanasamuke ku mtundu watsopano wa insulin. Mukasamutsa odwala omwe ali pamaziko a insulin, mlingo wa Ryzodeg ® uyenera kuwerengedwa potengera zosowa za wodwala. Monga lamulo, odwala amayamba ndi kumwa womwewo wa basal insulin.

Odwala omwe ali ndi matenda a shuga 1. Mlingo woyambirira wa Ryzodeg ® FlexTouch ® ndi 60-70% ya insulin tsiku lililonse pophatikizana ndi insulin yochepa / yayikulu yocheperako yocheperako ndi zakudya zina ndikusankhidwa kwa mankhwalawo.

Malamulo osinthika a dosing

Nthawi ya kukhazikitsidwa kwa mankhwala Ryzodeg ® FlexTouch ® ingasinthe ngati nthawi yakudya yayikulu yasinthidwa.

Ngati mankhwalawa a Ryzodeg ® FlexTouch ® akusowa, wodwalayo atha kulowa mgawo lotsatira tsiku lomwelo ndikulandila, ndikulemba, ndikubwerera ku nthawi yake yeniyeni yoyambira mankhwalawo. Mlingo wowonjezera suyenera kuperekedwa kuti ulipirire amene wasowa.

Magulu apadera a odwala

Okalamba okalamba (woposa zaka 65). Ryzodeg ® FlexTouch ® ikhoza kugwiritsidwa ntchito mwa odwala okalamba. Yang'anirani mosamala kuchuluka kwa shuga m'magazi ndikusintha muyeso wa insulin payekhapayekha (onani "Pharmacokinetics").

Odwala ndi mkhutu aimpso ndi kwa chiwindi ntchito. Ryzodeg ® FlexTouch ® ikhoza kugwiritsidwa ntchito mwa odwala omwe ali ndi vuto la impso ndi chiwindi. Yang'anirani mosamala kuchuluka kwa shuga m'magazi ndikusintha muyeso wa insulin payekhapayekha (onani "Pharmacokinetics").

Ana ndi achinyamata. Zambiri zomwe zapezeka mu pharmacokinetic zimawonetsedwa mu gawo la Pharmacokinetics, komabe, kufunikira ndi chitetezo cha Ryzodeg ® FlexTouch ® mwa ana ndi achinyamata osakwana zaka 18 sizinaphunzire, ndipo malingaliro pa kumwa kwa mankhwalawa mu ana sanapangidwe.

Kukonzekera kwa Ryzodeg ® FlexTouch ® kumangokonzekera kachitidwe ka sc. Mankhwala Ryzodeg ® FlexTouch ® sangathe kutumizidwa iv. izi zimatha kuyambitsa kwambiri hypoglycemia. Mankhwala Ryzodeg ® FlexTouch ® sangathe kulowa / m, chifukwa motere, kuyamwa kwa mankhwalawa kumasintha. Ryzodeg ® FlexTouch ® sayenera kugwiritsidwa ntchito pamapampu a insulin.

Kukonzekera kwa Ryzodeg ® FlexTouch ® kumayikidwa pakhungu m'dera la ntchafu, khoma lamkati lakumbuyo kapena dera lamapewa. Masamba obayira amayenera kusinthidwa pafupipafupi m'dera lomwelo kuti muchepetse vuto la lipodystrophy.

Cholembera chimbale cha FlexTouch ® chapangidwa kuti chigwiritsidwe ntchito ndi singano zotayika NovoFayn ® kapena NovoTvist ®. FlexTouch ® imakupatsani mwayi kuti mulowetse Mlingo kuchokera 1 mpaka 80 mayunitsi mukukula kwa 1 unit.

Mayendedwe akugwiritsa ntchito mankhwalawa

Cholembera chopanda chodzaza Ryzodeg ® FlexTouch ® chimapangidwa kuti chigwiritsidwe ntchito ndi singano za NovoFine ® kapena NovoTvist ® mpaka 8 mm. Raizodeg ® FlexTouch ® imakupatsani mwayi kuti mulowetse Mlingo kuchokera 1 mpaka 80 mayunitsi mukuwonjezera kwa 1 unit. Tsatirani malangizo mwatsatanetsatane mu malangizo omwe aphatikizidwa ogwiritsa ntchito cholembera cha FlexTouch ®. Risodeg ® FlexTouch ® ndi singano ndizongogwiritsa ntchito nokha.

Osadzazitsanso katoni katemera.

Simungagwiritse ntchito mankhwalawa ngati yankho laleka kukhala lowonekera komanso lopanda utoto. Simungagwiritse ntchito mankhwalawa ngati adazizira.

Ponyani singano pambuyo pa jekeseni iliyonse. Onani malamulo apafupi ndi kwanuko Malangizo atsatanetsatane ogwiritsira ntchito cholembera - syringe malangizo a odwala pakugwiritsa ntchito mankhwala Risedeg ® FlexTouch ®.

Malangizo kwa odwala pakugwiritsa ntchito njira ya Ryzodeg ® FlexTouch ® yothetsera panjira ya 100 PIECES / ml

Muyenera kuwerenga malangizo awa musanayambe kugwiritsa ntchito cholembera cha syringe ya FlexTouch ®.

Ngati wodwalayo samatsata malangizowo, akhoza kupatsidwa insulin yokwanira kapena yayikulu kwambiri, yomwe ingayambitse kuchuluka kwambiri kwa shuga m'magazi. Gwiritsani ntchito cholembera pokhapokha wodwala atatha kugwiritsa ntchito motsogozedwa ndi dokotala kapena namwino.

Onani cholembera pa cholembera cholembera kuti muonetsetse kuti ili ndi Ryzodeg ® FlexTouch ®, 100 U / ml, kenako phunzirani mosamala zithunzi zomwe zikuwonetsedwa, zomwe zimawonetsa magawo osiyanasiyana a cholembera ndi singano.

Ngati wodwala ali ndi vuto la khungu kapena ali ndi vuto lalikulu lakuwona ndipo sangathe kusiyanitsa pakati pa manambala omwe akukwaniritsidwa, musagwiritse ntchito cholembera popanda thandizo.

Wodwalayo amatha kuthandizidwa ndi munthu popanda kuwonongeka kwa mawonekedwe, wophunzitsidwa bwino kugwiritsa ntchito cholembera cha FlexTouch ® chodzaza.

Ryzodeg ® FlexTouch ® ndi cholembera chodzaza ndi 300 IU cha insulin. Mlingo wapamwamba kwambiri womwe wodwalayo angathe kukhazikitsa ndi magawo 80 pazowonjezera za 1 unit. Cholembera cha Ryzodeg ® FlexTouch ® syringe chidapangidwa kuti chigwiritsidwe ntchito ndi singano zotayika NovoFayn ® kapena NovoTvist ® mpaka 8 mm kutalika. Zingano sizikuphatikizidwa mu phukusi.

Chidziwitso chofunikira. Kuti mugwiritse ntchito cholembera, chisamaliro chapadera chiyenera kulipidwa chofunikira.

Chithunzi 4. Ryzodeg ® FlexTouch ® - cholembera ndi singano (chilinganizo).

I. Kukonzekera cholembera kuti mugwiritse ntchito

A. Onani dzina ndi mlingo pa zilembo za cholembera kuti mutsimikizire kuti uli ndi kukonzekera kwa Ryzodeg ® FlexTouch ®, 100 PIECES / ml. Izi ndizofunikira kwambiri ngati wodwala agwiritsa ntchito mitundu yosiyanasiyana ya kukonzekera insulin. Ngati wodwalayo molakwika apereka insulin ina, kuchuluka kwa shuga m'magazi kumatha kukwera kwambiri kapena kutsika kwambiri.

Chotsani kapu ku cholembera.

B. Onetsetsani kuti yankho la insulin mu cholembera ndilowonekera komanso lopanda utoto. Onani pazenera la kukula kwa insulin. Ngati yankho la insulin ndi mitambo, cholembera sichitha kugwiritsidwa ntchito.

C. Tengani singano yatsopano yotaya ndikuchotsera chomata.

D. Ikani singano pa cholembera ndi kutembenuza kuti singano isapume pa cholembera.

E. Chotsani thumba lakunja la singano, koma osalitaya. Zidzafunika mukamaliza jakisoni kuti muchotsere singano bwinobwino.

F. Chotsani ndikutaya singano yamkati. Wodwalayo akafuna kubwezeretsa singano yamkati pabowo, angagwe. Dontho la insulin lingathe kuoneka kumapeto kwa singano. Izi ndizabwinobwino, komabe, ndikofunikira kuunika kuti insulini iperekedwe.

Chidziwitso chofunikira. Gwiritsani ntchito singano yatsopano jekeseni iliyonse. Izi zimachepetsa chiopsezo cha matenda, matenda, kuchepa kwa insulin, kutuluka kwa singano ndikukhazikitsa njira yolakwika ya mankhwala.Osamagwiritsanso ndi singano ngati yakunga kapena yowonongeka.

II. Chingwe cha Insulin

G. Pamaso jakisoni aliyense, yang'anani kudya kwa insulin, kotero kuti wodwalayo atsimikizire kuti mlingo wa insulin umaperekedwa kwathunthu.

Imbani 2 magawo a mankhwala ndikusintha chosankha. Onetsetsani kuti zida zotsalira zikuwonetsa "2".

H. Mukugwira cholembera ndi singano kumtunda, dinani mopepuka pamwamba pa cholembera kambirimbiri ndi cholembapo chanu kuti thovu lakutsogolo lisunthe.

I. Kanikizani batani loyambira ndikuligwirizitsa mpaka mawonekedwe a mankhwalawo abwerera zero. "0" akhale kutsogolo kwa chizindikiro. Dontho la insulin liyenera kuonekera kumapeto kwa singano.

Mpweya wawung'ono ungakhale kumapeto kwa singano, koma osavulala. Ngati dontho la insulin silikuwoneka kumapeto kwa singano, bwerezaninso ntchito IIG - II I, koma osapitirira 6 times. Ngati dontho la insulin silikuwoneka, sinthani singano ndi kubwereza ntchito IIG - II I. Musagwiritsenso ntchito cholembera ngati dontho la insulin silikuwoneka kumapeto kwa singano.

Chidziwitso chofunikira. Pamaso pa jekeseni iliyonse, onetsetsani kuti dontho la insulin limatuluka kumapeto kwa singano. Izi zimapangitsa kuti insulin iperekedwe. Ngati dontho la insulin silikuwoneka, mlingo wake sudzaperekedwa, ngakhale wotsutsa wa dokotalayo asunthe. Izi zitha kuwonetsa kuti singanoyo yaboweka kapena yowonongeka. Jekeseni iliyonse isanachitike, insulin imayenera kuyang'aniridwa. Wodwala akapanda kuyang'ana kuchuluka kwa insulin, sangathe kupereka insulin yokwanira kapena ayi, zomwe zingayambitse kuchuluka kwa shuga m'magazi.

Kukhazikitsidwa kwa mlingo wa III

J. Musanayambe jakisoni, onetsetsani kuti pulogalamu yotsitsa yaikidwa kuti "0". "0" akhale kutsogolo kwa chizindikiro.

Pogwiritsa ntchito chosankha cha mankhwalawa, sinthani mulingo womwe mwayesedwa ndi dokotala kapena namwino. Ngati mulibe mlingo woyenera, mutha kusinthitsa osankhiratu a mankhwalawo kutsogolo kapena kubwerera kumbuyo kufikira mutapeza mlingo woyenera. Mlingo wapamwamba kwambiri womwe wodwala angakhazikitse ndi magawo 80.

Wosankha mlingo umayika kuchuluka kwa mayunitsi. Chidindo chokhacho cha mlingo ndi chiwonetsero cha mlingo chomwe chikuwonetsa kuchuluka kwa magawo a insulin mu mlingo wosankhidwa. Mlingo wapamwamba kwambiri womwe ungakhazikitsidwe ndi magawo 80. Ngati insulini yotsalira mu cholembera sichikhala yochepera 80, koloko ya mankhwalawo idzaima paliponse pomwe panali insulini.

Kutembenuka kulikonse kwa chosankha cha mankhwala, kumadina kumamveka, kumveka kwa mabatani kumadalira mbali yomwe wosankha wa mankhwalawo akutembenukira (kutsogolo, kumbuyo, kapena ngati mlingo womwe watenga umaposa kuchuluka kwa UNITS ya insulini yotsalira mu cholembera). Makina awa sikuyenera kuwerengedwa.

Chidziwitso chofunikira. Pamaso pa jekeseni aliyense, muyenera kuwunika kuchuluka kwa UNIT ya insulin yomwe wodwalayo adalemba pamakina ogwirira ndi mlingo. Osawerengetsa zokhoma za cholembera. Ngati mulingo woyenera wokhazikitsidwa ndikuwathandizira, kuchuluka kwa shuga m'magazi kumatha kukhala kokwezeka kwambiri kapena kotsika kwambiri. Mlingo wa insulini ukuwonetsa kuchuluka kwa insulini yotsalira mu cholembera, motero sangagwiritsidwe ntchito kuyeza kuchuluka kwa insulin.

IV kuyang'anira insulin

K. Ikani singano pansi pa khungu lanu pogwiritsa ntchito jakisoni woperekedwa ndi dokotala kapena namwino. Tsimikizani kuti mankhwala othandizira ali mgulu la odwala. Osakhudza chida cha mankhwalawo ndi zala zanu - izi zitha kusokoneza jakisoni. Kanikizani batani loyambira njira yonse ndikuigwirizira mpaka nthawi yotsutsa idawonetsa "0". "0" iyenera kukhala yosiyana kwenikweni ndi chizindikiro. Potere, wodwalayo amamva kapena kumva kudina. Pambuyo pa jekeseni, siyani singano pansi pa khungu kwa masekondi 6 osachepera. Izi zikuthandizira kukhazikitsidwa kwa insulin yonse.

L. Chotsani singano pansi pa khungu ndikukoka chogwirizira ndi syringe. Ngati magazi abwera pamalo a jakisoni, kanikizani kaye pang'ono thonje la thonje kumalowo. Musamasewetse malo a jakisoni.

Jakisoni itatha, wodwalayo amatha kuwona dontho la insulin kumapeto kwa singano. Izi ndizabwinobwino ndipo sizikhudza mlingo wa mankhwala omwe wodwalayo wapereka.

Chidziwitso chofunikira.Nthawi zonse muziwonetsetsa kuti pali mankhwala angati a insulin omwe wodwalayo wapereka. Wogulitsa mlingo akuwonetsa kuchuluka kwa UNITS. Osawerengetsera zamambala. Gwiritsani ntchito batani loyambira mpaka atagwirizana ndi jekeseni atawonetsa "0". Ngati mankhwala othandizira atayima asanawonetse "0", insulin yonse siyinalowe, zomwe zingayambitse kuchuluka kwa shuga m'magazi.

V. Mukamaliza jakisoni

M. Ndi singano yakunja yopumira pamalo athyathyathya, ikani kumapeto kwa singano mu kapu osakhudza kapena nsonga ya singano.

N. Pamene singano ilowa mu capu, iduleni bwino. Tulutsani singano. Iponyeremo mosamala.

A. Pakapita jakisoni aliyense, chipewa chimayenera kuyikiridwa ndi cholembera kuti chiziteteza ku kuwala.

Ndikofunikira kutaya singano pambuyo pobayira jekeseni iliyonse kuti mupewe matenda, matenda, kutulutsa insulini, kutsekeka kwa singano ndikukhazikitsa njira yolakwika ya mankhwala. Ngati singano yatsekedwa, wodwalayo sangathe kubaya insulini. Taya cholembera chogwiritsidwa ntchito ndi singano yolumikizidwa, mogwirizana ndi malingaliro omwe dokotala wanu, namwino, wopanga mankhwala kapena malinga ndi zofuna zakomweko.

Chidziwitso chofunikira. Kuti mupewe misala yovulala mwangozi, musayese kubwezeretsanso singano yamkati pa singano. Chotsani singano pambuyo pa jekeseni iliyonse ndikusunga cholembera kuti singano isokonekere. Izi zimathandiza kupewa, kutenga kachilomboka, kutulutsa insulin, kutulutsa masingano ndi kukhazikitsa njira yolakwika ya mankhwala.

VI Kodi insulini yatsala bwanji?

P. Mulingo wotsalira wa insulin ukuwonetsa kuchuluka kwa insulini yotsalira mu cholembera.

R. Kuti mudziwe kuchuluka kwa insulini yomwe yatsala mu cholembera, gwiritsani ntchito kiyendetsedwe ya mlingo: muzungulirani chosankha cha mankhwala mpaka wotsutsa wa mankhwalawo atasiya. Ngati cholembera chikuonetsa manambala 80, izi zikutanthauza kuti pafupifupi ma PISCES a 80 a insulin amakhalamo cholembera. Ngati cholembera cha mankhwalawo chikuwonetsa zosakwana 80, izi zikutanthauza kuti ndendende kuchuluka kwa UNITS ya insulin yomwe imawonetsedwa pa cholembera cha asidi imakhalabe mu cholembera. Sungani chosankha cha mtundu wina mpaka cholowa chikuonetsa "0". Ngati insulini yotsala mu cholembera siyikwanira kuperekera mlingo wonse, mutha kulowetsamo ma jakisoni awiri pogwiritsa ntchito zolembera ziwiri.

Chidziwitso chofunikira. Muyenera kusamala kwambiri mukamawerengera zotsala za insulin zofunika. Ngati mukukayika, ndibwino kuperekanso insulin yonse pogwiritsa ntchito cholembera chatsopano. Wodwala akakhala kuti walakwitsa, amawonetsa insulin yokwanira kapena yayikulu kwambiri. Izi zitha kupangitsa kuti magazi a glucose azikhala kwambiri kapena otsika kwambiri.

Chidziwitso chofunikira. Nthawi zonse muzinyamula cholembera. Nthawi zonse gwiritsani cholembera ndi masingano atsopano ngati atayika kapena kuwonongeka.

Sungani cholembera ndi singano kuti aliyense sangathe, makamaka ana. Musagawireko cholembera ndi singano yanu kwa ena. Izi zimatha kudzetsa matenda opatsirana. Osamagawana cholembera chanu ndi ena. Izi zitha kukhala zovulaza thanzi lawo.

Osamalira ayenera kugwiritsa ntchito singano zogwiritsidwa ntchito mosamala kwambiri kuti apewe kubayidwa mwangozi komanso matenda oyambukira.

Chisamaliro cha cholembera

Cholembera cha syringe chikuyenera kusamalidwa bwino. Kugwira mosasamala kapena mosayenera kungayambitse mlingo woyenera, womwe ungayambitse kuchuluka kwambiri kwa glucose m'magazi. Osasiya cholembera m'galimoto kapena malo ena aliwonse pomwe angayikidwe ndi kutentha kwambiri kapena kutentha kwambiri. Tetezani cholembera ku fumbi, litsiro ndi mitundu yonse ya zakumwa. Osasamba cholembera, osamiza m'madzi kapena kumuthira mafuta. Ngati ndi kotheka, cholembera cha syringe chimatha kutsukidwa ndi nsalu yonyowa pokonza yotsekemera ndi chowonjezera chofewa.

Osaponya kapena kugunda cholembera pamalo olimba. Wodwalayo akaponya cholembera kapena amakayikira kuti sichitha kugwira ntchito, ndikofunikira kuphatikiza singano yatsopano ndikuyang'ana kuchuluka kwa insulin musanapange jakisoni.

Kudzazitsa cholembera sichiloledwa. Cholembera chopanda kanthu ziyenera kutayidwa. Simuyenera kuyesa kukonzanso syringe pokha kapena kuyipatula.

Bongo

Zizindikiro mlingo wofunikira wa mankhwala osokoneza bongo ambiri a insulin sanakhazikitsidwe, koma hypoglycemia imatha kukula pang'onopang'ono ngati mlingo wa mankhwalawo ndiwokwera kwambiri poyerekeza ndi zomwe wodwala akufuna (onani "Maupangiri Apadera").

Chithandizo: wodwalayo amatha kuthetsa hypoglycemia wofatsa pogwiritsa ntchito shuga kapena mankhwala okhala ndi shuga mkamwa. Chifukwa chake, ndikulimbikitsidwa kwa odwala omwe ali ndi matenda ashuga kuti azitha kutenga zakudya zomwe zili ndi shuga. Ngati vuto la hypoglycemia litavuta, wodwalayo akapanda kudziwa, ayenera kupatsidwa glucagon (0.5 mpaka 1 mg IM kapena s / c) akhoza kuyendetsedwa ndi munthu wophunzitsidwa bwino, kapena IV yankho la dextrose (glucose) (ingathe kutumikiridwa kokha Wofunsidwa.) Ndikofunikanso kuyendetsa dextrose iv ngati wodwalayo sakudziwikanso pambuyo pa mphindi 10-15 pambuyo pakuyambiranso. Pambuyo pobwezeretsa chikumbumtima, wodwalayo akulimbikitsidwa kudya zakudya zopatsa thanzi kuti muchepetse kubwereranso kwa hypoglycemia.

Malangizo apadera

Hypoglycemia. Kudumpha zakudya kapena kuchita masewera olimbitsa thupi mosakonzekera kungayambitse kukula kwa hypoglycemia. Hypoglycemia imatha kukhala ngati mlingo wa insulin ndi wokwera kwambiri mogwirizana ndi zosowa za wodwalayo (onani "Zotsatira zoyipa" ndi "Overdose"). Atalipira chakudya cha metabolism (mwachitsanzo, ndi insulin Therapy), odwala amatha kukumana ndi zisonyezo zam'mbuyomu za hypoglycemia, zomwe odwala ayenera kudziwitsidwa. Zizindikiro zachilendo zimatha kutha ndi matenda a shuga.

Matenda okhala ndi vuto limodzi, makamaka opatsirana komanso kutentha thupi, nthawi zambiri amalimbikitsa kufunika kwa insulin. Kusintha kwa magazi kungafunikenso ngati wodwala ali ndi vuto la impso, chiwindi, kapena adrenal gland, pituitary, kapena chithokomiro. Monga momwe zimakhazikitsira insulini ina kapena kukonzekera ndi chigawo chapansi, kuchira pambuyo pa hypoglycemia pogwiritsa ntchito kukonzekera kwa Ryzodeg ® FlexTouch ® kungachedwe.

Hyperglycemia. Zochizira kwambiri za hyperglycemia, insulin yolimbikira imalimbikitsidwa. Mlingo wosakwanira komanso / kapena kutha kwa mankhwalawa kwa odwala omwe amafunikira insulin kungayambitse kukula kwa hyperglycemia ndipo mwina matenda ashuga a ketoacidosis. Kuphatikiza apo, matenda ophatikizika, makamaka opatsirana, amatha kuthandizira kukulitsa mikhalidwe ya hyperglycemic ndipo, motero, kukulitsa kufunika kwa insulin. Monga lamulo, zizindikiro zoyambirira za hyperglycemia zimawonekera pang'onopang'ono, kwa maola angapo kapena masiku. Zizindikiro zake zimaphatikizaponso ludzu, kukodza mwachangu, kusanza, kusanza, kugona komanso kuyanika pakhungu, pakamwa pouma, kusowa chilimbikitso, kununkhira kwa acetone mumlengalenga wotuluka. Mtundu woyamba wa matenda a shuga 1 mellitus, popanda kulandira chithandizo choyenera, hyperglycemia imabweretsa chitukuko cha matenda ashuga a ketoacidosis, mkhalidwe womwe ukhoza kupha.

Tumizani wodwala kuchokera kukonzekera kwina kwa insulin. Kusamutsa wodwala kupita ku mtundu wina kapena kukonzekera kwa insulin yatsopano kapena wopanga wina kuyenera kuchitika moyang'aniridwa ndi achipatala. Mukamasulira, kusintha kwa mankhwala kungafunikire.

Kugwiritsa ntchito munthawi yomweyo mankhwala a gulu la thiazolidinedione komanso kukonzekera insulin. Milandu yachitukuko cha CHF yanenedwa pamankhwala a odwala omwe ali ndi thiazolidinediones kuphatikiza ndi kukonzekera kwa insulin, makamaka ngati odwala oterewa ali ndi chiopsezo chotukuka kwa mtima wodwala. Izi zimayenera kukumbukiridwa popereka mankhwala ophatikiza ndi thiazolidinediones ndi mankhwala a Ryzodeg ® FlexTouch ® kwa odwala.

Mukamapereka mankhwala othandizira, muyenera kuyeserera kwa odwala kuti muwone ngati ali ndi vuto la mtima, kuwonda komanso kupezeka kwa zotumphukira za edema. Ngati zizindikiro za kulephera kwa mtima zikuchulukirachulukira kwa odwala, chithandizo ndi thiazolidatediones ziyenera kusiyidwa.

Kuphwanya gawo la masomphenyawo. Kulimbitsa kwa insulin mankhwala ndikusintha kolimba kwa mphamvu ya kagayidwe kazakudya kungayambitse kuwonongeka kwakanthawi mu matenda a shuga, pomwe kusintha kwakanthawi kwakanthawi ka glycemic kumachepetsa chiopsezo cha kupitirira kwa matenda ashuga retinopathy.

Kupewa mwangozi kusokonezeka kwa insulin kukonzekera. Wodwalayo ayenera kulangizidwa kuti alembedwe zilembo chilichonse chomwe chalembedwapo pamaso povulala aliyense kuti apewe kusokonezeka kwa Ryzodeg ® FlexTouch ® kukonzekera ndi kukonzekera kwina kwa insulin.

Odwala amayenera kudziwa kuti ali bwanji pa jakisoni wa jakisoni. Chifukwa chake, odwala okhawo omwe amatha kusiyanitsa manambala pa cholembera cha syringe ndi omwe amatha kubayira insulin okha.

Ndikofunikira kudziwitsa odwala omwe ali ndi vuto lakhungu kapena anthu omwe ali ndi vuto lowonera kuti nthawi zonse amafunikira thandizo la anthu omwe alibe mavuto ammaso ndipo amaphunzitsidwa kugwira ntchito ndi jakisoni.

Ma antibodies kupita ku insulin. Mukamagwiritsa ntchito insulin, mapangidwe a antibody ndiwotheka. Nthawi zina, mapangidwe a antibody angafunikire kusintha kwa insulin kuti mupewe milandu ya hyperglycemia kapena hypoglycemia.

Kukopa pa luso loyendetsa magalimoto ndi zida. Kuthekera kwa odwala kulolera komanso kuchuluka kwa zomwe angachite kungayambitse vuto la hypoglycemia, zomwe zimatha kukhala zowopsa nthawi zomwe luso limafunikira makamaka (mwachitsanzo, poyendetsa magalimoto kapena kugwira ntchito ndi makina).

Odwala ayenera kulangizidwa kuti achitepo kanthu popewa kukula kwa hypoglycemia mukamayendetsa. Izi ndizofunikira kwambiri kwa odwala omwe alibe kapena kuchepa kwa zizindikiro zakutsogolo kwa hypoglycemia kapena magawo a hypoglycemia. Muzochitika izi, kuyenera koyendetsa galimoto kuyenera kuganiziridwanso.