Kuyesa kwa insulin
Kuchuluka kwa insulin m'magazi kumasintha mosalekeza tsiku lonse poyankha kutuluka kwa glucose m'matumbo. M'matenda ena, kusokoneza bwino kumasokonekera, kapangidwe ka timadzi timeneti timayamba kukhala osiyana ndi chikhalidwe. Kuyesedwa kwa magazi kwa insulin kumakuthandizani kuti muwone kupatuka kwakanthawi.
Nthawi zina, mwachitsanzo, ndi metabolic syndrome, kuzindikira nthawi yake ndikofunikira, popeza wodwalayo ali ndi mwayi wochiritsa matenda omwe angayambitse komanso kupewa matenda ashuga. Kusanthula uku kumakupatsani mwayi wofufuza zochitika za kapamba, ndi gawo limodzi la maphunziro kuti mudziwe zomwe zimayambitsa hypoglycemia. Mu shuga mellitus, kuchuluka kwa insulin yofulumira m'magazi kumagwiritsidwa ntchito kuwerengera index insulin.
Zifukwa Zogawirira Kusanthula
Insulin ndiye mahomoni ofunika kwambiri mu kayendetsedwe kazinthu zovuta za carbohydrate. Amapangidwa mu kapamba mothandizidwa ndi maselo amtundu wapadera - maselo a beta, amapezeka m'masukulu a Langerhans. Insulin imatulutsidwa m'magazi ndikuwonjezera kuchuluka kwa shuga m'magazi. Zimapangitsa kusintha kwa glucose kulowa m'matumbo, chifukwa momwe mulingo wake m'magazi umachepa, ndipo patapita kanthawi kuchuluka kwa mahomoni kumatsika. Kuti mupeze kupanga insulin, magazi amatengedwa pamimba yopanda kanthu, itatha nthawi yanjala nthawi yayitali. Pankhaniyi, kuchuluka kwake mwa anthu athanzi nthawi zonse kumakwanira muyezo, ndipo kupatuka kulikonse ndi chizindikiro cha kusokonezeka kwa kagayidwe kazakudya.
Kuwunika kochitidwa pamimba yopanda kanthu m'mabotolo osiyanasiyana kungatchulidwe immunoreactive insulin, basal insulin, IRI. Gawani m'milandu yotsatirayi:
- kuchuluka kapena kuchepa thupi komwe sikungafotokozedwe ndi zakudya,
- hypoglycemia mwa anthu osalandira chithandizo cha matenda ashuga. Amawonetsedwa mukumva njala yayikulu, miyendo, kunjenjemera,
- ngati wodwala ali ndi zizindikiro zingapo za prediabetes: kunenepa kwambiri ndi BMI> 30, atherosclerosis, mtima ischemia, polycystic ovary,
- munthawi zokayikitsa, kumveketsa mtundu wa matenda osokoneza bongo kapena kusankha mtundu wa mankhwala omwe mumakonda.
Zomwe mayeso a insulin amawonetsa
Kuyesa kwa insulin kumakupatsani mwayi:
- Dziwani zotupa, zomwe zimaphatikizapo maselo omwe amatha kutulutsa insulin. Poterepa, timadzi timene timatulutsidwa m'magazi osayembekezereka, pamiyeso yambiri. Kuwunikaku sikugwiritsidwa ntchito kuti mupeze vuto lokhala ndi mankhwalawa, komanso kuti muwone bwino momwe opaleshoni yake imathandizira, kuti athe kubwezeretsanso.
- Unikani minyewa yomwe ingayambitse insulin - kukana insulin. Pankhaniyi, muyenera nthawi yomweyo kuyesa shuga. Kukana kwa insulini kumadziwika ndi matenda amtundu wa 2 komanso zovuta zomwe zimayambitsa: prediabetes ndi metabolic syndrome.
- Pankhani ya matenda a shuga a 2 a mtundu wautali, kuwunikaku kumawonetsa kuchuluka kwa momwe kapamba amapangira komanso ngati wodwala azikhala ndi mapiritsi okwanira shuga kapena insulin yovomerezeka. Kuwunikidwaku kumachitidwanso pambuyo pothandizidwa ndi matenda oopsa a hyperglycemic, pomwe wodwala wa matenda a shuga amamuchokera ku insulin.
Ndi matenda a shuga 1 amtunduwu, kuwunika kumeneku sikugwiritsidwa ntchito. Kumayambiriro kwa matendawa, ma antibodies omwe amapangidwa amasokoneza kutanthauzira kolondola kwa zotsatira zake; atayamba chithandizo, insulin yokonzekera yomwe ili yofanana ndi mahomoni awo. Njira ina yabwino kwambiri pamenepa ndi kuwunikira kwa C-peptide. Izi zimapangidwa nthawi imodzi ndi insulin. Ma antibodies samayankha, ndipo kukonzekera kwa C-peptide kulibe.
Ndi minyewa ya dystrophy, Itsenko-Cushing's syndrome, matenda opha ziwalo, matenda a chiwindi, ndikofunikira kuyang'anira magwiridwe antchito a ziwalo zonse, chifukwa chake, odwala, pamodzi ndi maphunziro ena, amafunikira kuyesedwa kawirikawiri ndi insulin.
Momwe mungawerengere
Kuchuluka kwa insulin m'magazi sikudalira kuchuluka kwa shuga, komanso pazinthu zina zingapo: zolimbitsa thupi, mankhwala osokoneza bongo komanso mkhalidwe wamunthu wamunthu. Kuti zotsatira za kusanthula zikhale zodalirika, kukonzekera kuyenera kuthandizidwa mwachidwi:
- Kwa masiku awiri, kupatula zakudya zamafuta kwambiri. Sikoyenera kukana chakudya ndi mafuta abwinobwino.
- Kwa tsiku, chotsani katundu onse mopindulitsa, osangokhala zathupi zokha, komanso zamaganizidwe. Kupsinjika mtima patsiku lachiwonetserocho ndi chifukwa chochedwetsa magazi.
- Tsiku silimamwa mowa komanso mphamvu, musasinthe zakudya zomwe mumadya. Lekani kwakanthawi mankhwala onse ngati izi sizikuvulaza thanzi. Ngati kuleka kusatheka, dziwitsani ogwira nawo ntchito.
- Maola 12 osadya. Madzi okhaokha osatulutsidwa popanda mpweya ndi omwe amaloledwa pa nthawi ino.
- 3 maola osasuta.
- Mphindi 15 musanatenge magazi, khalani chete kapena kugona pakama.
Nthawi yabwino yoyeserera ndi 8-11 m'mawa. Mwazi umatengedwa kuchokera mu mtsempha. Kutsogolera njirayi kwa ana aang'ono, theka la ola nthawi isanayambike ayenera kupereka kapu yamadzi kuti amwe.
Mankhwala omwe amakhudza kuchuluka kwa insulin:
Kuchulukitsa | Chepetsani |
Mankhwala onse okhala ndi shuga, fructose, sucrose. | Diuretics: furosemide, thiazides. |
Mahomoni: Kulera kwa pakamwa, danazole, glucagon, kukula kwa hormone, cholecystokinin, prednisone ndi ena. | Mahomoni: thyrocalcitonin. |
Hypoglycemic mankhwala opangidwa ndi matenda ashuga: acetohexamide, chlorpropamide, tolbutamide. | Mankhwala a Hypoglycemic: Metformin. |
Salbutamol | Phenobarbital |
Kashiamu gluconate | Beta blockers |
Decoding ndi miyambo
Zotsatira za kusanthula, kuchuluka kwa insulini m'magazi kumawonetsedwa m'magawo osiyanasiyana: mkU / ml, mU / l, pmol / l. Kusamutsa iwo kumodzi ndikosavuta: 1 mU / l = 1 μU / ml = 0.138 pmol / l.
Miyezo yoyenera:
Gulu la anthu | Norm | |
μU / ml, uchi / l | pmol / l | |
Ana | 2,7-10,4 | 19,6-75,4 |
Akuluakulu ochepera zaka 60 ndi BMI ya 30 | 2,7-24,9 | 19,6-180 |
Akuluakulu atatha zaka 60 | 6,0-36,0 | 43,5-261 |
Makhalidwe abwinobwino a insulin amatengera luso la kusanthula, choncho m'malo ena olemba mankhwalawo amatha kusiyanasiyana. Mukalandira zotsatira, ndikofunikira kuyang'ana pa data yomwe mwapatsidwa ndi ogwira ntchito, osati zongoganiza.
Insulin pamwamba kapena pansipa
Kuperewera kwa insulin kumabweretsa kufa ndi maselo komanso kuchuluka kwa shuga m'magazi. Zotsatira zake zitha kukhala zotsika pang'ono kuposa zokhazokha ndi matenda a pituitary ndi hypothalamus, kupsinjika ndi kutopa kwambiri, ndikulimbitsa thupi kwa nthawi yayitali kuphatikiza ndi kusowa kwa chakudya chamagulu, ndimatenda opatsirana ndipo nthawi yomweyo itatha.
Doctor of Medical Science, Mutu wa Institute of Diabetesology - Tatyana Yakovleva
Ndakhala ndikuphunzira matenda a shuga kwa zaka zambiri. Zimakhala zowopsa anthu ambiri akamwalira, ndipo makamaka amakhala olumala chifukwa cha matenda ashuga.
Ndithamangira kunena mbiri yabwino - Endocrinological Research Center ya Russian Academy of Medical Sayansi yakwanitsa kupanga mankhwala omwe amachiritsiratu matenda ashuga. Pakadali pano, kugwiritsa ntchito bwino kwa mankhwalawa kuyandikira 98%.
Nkhani ina yabwino: Unduna wa Zaumoyo wateteza kukhazikitsidwa kwa pulogalamu yapadera yomwe imalipira mtengo wa mankhwalawo. Ku Russia, odwala matenda ashuga mpaka Meyi 18 (kuphatikiza) nditha kuipeza - Kwa ma ruble 147 okha!
Kuchepa kwakukulu kwa insulin kumawonetsa kuyambika kwa mtundu wa matenda a shuga 1 kapena kusokonekera kwa kapamba ka ntchito kwa odwala omwe ali ndi matenda a shuga a 2. Acute pancreatitis ndi pancreatic necrosis amathanso kukhala chifukwa.
Insulin yokwera m'mwazi imawonetsa zovuta zotsatirazi:
- Matenda a shuga osagwirizana ndi insulin. Matendawa akamakula, kuchuluka kwa insulini kudzachepa, ndipo shuga wamagazi amayamba kuchuluka.
- Insulinoma ndi chotupa chomwe chimatha kupanga ndikupanga insulin yokha. Nthawi yomweyo, palibe mgwirizano pakati pa kudya shuga ndi syntulin, chifukwa chake hypoglycemia ndi chizindikiritso cha insulinoma.
- Kukana kwamphamvu kwa insulin. Awa ndi mkhalidwe womwe thupi limatha kuzindikira insulin. Chifukwa cha izi, shuga samasiya magazi, ndipo kapamba amakakamizidwa kuti azitha kupanga mahomoni ena. Kukana kwa insulin ndi chizindikiro cha zovuta za metabolic, kuphatikizapo mitundu iwiri ya matenda ashuga. Zimagwirizanitsidwa kwambiri ndi kunenepa kwambiri: zimakula pamene mukulira thupi, ndipo insulin yochulukirapo, imathandizira kuchedwetsa mafuta atsopano.
- Matenda omwe amaphatikizidwa ndi kuphatikiza kwakukulu kwa insulin antagonist mahomoni: Itsenko-Cushing's syndrome kapena acromegaly. Ndi acromegaly, adenohypophysis imapanga kukula kwakukulu kwa mahomoni. Itsenko-Cushing's syndrome limayendera limodzi ndi kuchuluka kwa mahomoni a adrenal cortex. Ma mahomoniwa amachepetsa mphamvu ya insulin, motero kaphatikizidwe kake kamakomoka.
- Herederal kagayidwe kachakudya matenda a galactose ndi fructose.
Kuchulukitsa kwabodza kwa insulin kumachitika ndikukonzekera kosayenera kusanthula ndi kukhazikitsa mankhwala ena.
Mtengo wowunikira m'mabotolo osiyanasiyana umachokera ku 400 mpaka 600 ma ruble. Zopeza za magazi zimalipiridwa mosiyana; mtengo wake umakhala mpaka ma ruble 150. Phunziroli limayamba nthawi yomweyo, kotero tsiku lotsatira lochita ntchito mutha kupeza zotulukapo zake.
>> Kuyesa magazi kwa shuga - pamatani, momwe mungatenge ndikusintha zotsatira.
Onetsetsani kuti mwaphunzira! Kodi mukuganiza kuti kuyamwa kwa mapiritsi ndi insulini kwa nthawi yonse yokhayo ndi njira yokhayo yosungira shuga m'manja? Sichowona! Mutha kutsimikizira izi nokha ndikuyamba kuzigwiritsa ntchito. werengani zambiri >>
Zizindikiro zoyeserera magazi a insulin
Kuyeza kumeneku nthawi zambiri kumagwiritsidwa ntchito kuti muunikire zomwe zimayambitsa hypoglycemia (shuga m'magazi) kapena zinthu zina zilizonse zokhudzana ndi kupanga insulin. Mchitidwewu nthawi zambiri umagwiritsidwa ntchito pofufuza komanso kuwunika insulin, momwe ma minofu amalephera kuzindikira zovuta zake, pomwe amachititsa chiphuphu cha pancreatic ndikupanga insulin yambiri.
Kukana kwa insulin kumakhala kofala pakati pa anthu onenepa omwe angalimbikitse kukula kwa matenda a shuga a 2, komanso azimayi omwe ali ndi polycystic ovarian syndrome.
Mankhwala a insulin ndi ochepa kwambiri, ngakhale amakhala ndi shuga wambiri - mwa ana omwe ali ndi matenda ashuga 1. Zizindikiro za matenda ashuga zomwe zimachitika pakadali pano zimaphatikizaponso ludzu lalikulu kapena njala, njala ngakhale mutatha kudya, kukoka pafupipafupi kapena kuwonjezereka, kumva kulira m'manja kapena m'mapazi, kumva kutopa kwambiri, komanso matenda opatsirana pafupipafupi.
Ngati wodwalayo alibe zizindikiro zowonekera, kukana insulini, dziko la prediabetes, komanso matenda ashuga nthawi zambiri amapezeka poyesa magazi. Kuyesedwa kwa matenda ashuga kuyenera kulembedwa pafupifupi zaka 40, komanso kuyesedwa kwa cholesterol komanso zolemba zina zaumoyo. Zabwino, wodwala amatha kuyesedwa pakuwunika akatswiri pachaka.
Kuyesedwa akadali achichepere kungalimbikitsidwe ngati wodwala:
- kumakhala moyo wongokhala
- ali ndi otsika kwambiri a "cholesterol yabwino" (HDL) kapena ma triglycerides ambiri,
- ali ndi abale awo odwala matenda ashuga,
- ali ndi kuthamanga kwa magazi
- Ili ndi zizindikiro za insulin,
- ali ndi matenda ashuga (nthawi yayitali pomwe matenda ashuga amakula pokhapokha ngati ali ndi pakati).
Ngakhale zotsatira zoyeserera ndizabwinobwino, tikulimbikitsidwa kuyesedwa kangapo chaka chilichonse. Ana ndi achinyamata azaka zapakati pa 10 mpaka 18 amathanso kugwiritsa ntchito zowunika ngati ali onenepa kwambiri kapena zinthu zina zomwe zalembedwa.
Kukonzekera kuyesedwa kwa magazi kwa insulin ndi algorithm yake
Atapima mozama, adokotala amauza wodwalayo ngati amwe mankhwala apadera mayeso ake asanachitike. Nthawi zina mwana amafunika kupewa kudya ndi kumwa kwa maola 8 asanayambe mayeso. Monga lamulo, madokotala amapatsa cheke panthawi yake komanso panthawi inayake, mwachitsanzo, atangodya.
Wothandizira labotale amatenga magazi a venous pogwiritsa ntchito syringe yotaya. Tsambalo liponya mothandizidwa ndi antiseptic. Bandeji yolimba imayikidwa pamwamba pa mtsempha.
Mitsempha itatha kuwonekera bwino, katswiri wa labotale akhonya mitsempha ndikutenga magazi ofunikira.
Pambuyo pa ndondomekoyi, ulendowu wamasulidwa, singano imachotsedwa, ndikuvala chovala cha antiseptic kumayikidwa pamalo opunthira (ndikofunikira kuti dzanja lanu lizigwedezeka pamapewa osachepera mphindi zisanu kuti hematoma isapangike). Kutolerera magazi kuyezetsa kumangotenga mphindi zochepa.
Zotsatira za Kusanthula ndi Zoopsa
Kuphatikiza magazi ndi njira yotetezedwa bwino yomwe imadzetsa kusasangalala pang'ono. Gawo la magazi lidzasinthidwa ndi makina apadera. Zotsatira nthawi zambiri zimapezeka mkati mwa masiku ochepa.
Kuyesedwa kwa insulin kumawonedwa ngati kopanda vuto lililonse, komabe, pakumwa magazi, zovuta zina zingachitike. Izi zimaphatikizapo: kukomoka kapena kumva kuti ndikumva chizungulire, hematoma (magazi omwe amatengedwa pansi pa khungu amatha kuyambitsa chifuwa), ululu womwe umapangidwa ndi jekeseni angapo posaka mtsempha. Ndikofunika kukumbukira kuti kuwunika kuyenera kutengedwa m'makiriniki odalirika, ndipo magolovesi osalala okha ndi syringe yotayika ndiyomwe ingagwiritsidwe ntchito pochita.
Ngati wodwala ali ndi matenda a prediabetes, pali njira yothanirana ndi matendawa. Kuti muchite izi, muyenera kusankha zakudya zopatsa thanzi (tikulimbikitsidwa kukaonana ndi katswiri wazakudya) kapena kuwunika pafupipafupi. Odwala onenepa kwambiri amalangizidwa kuti azidya zakudya ndipo ataye pafupifupi 7 peresenti ya kulemera kwawo.
Njira yoyenera ya moyo, kuyenda mu mpweya watsopano, masewera, kudya moyenera - zonsezi zimathandiza kuti mulingo wa insulini komanso shuga.
Ndikofunikira kukumbukira kuti kuzindikira kwa insulin kapena prediabetes ndi chenjezo lalikulu. Wodwala aliyense akamalandira chithandizo chamanthawi yake komanso moyenera, komanso momwe angasinthire njira yolondola, amatha kuchotsa matendawa ndikuwonetsa ntchito yonse yamoyo.
Kukonzekera ndi kutumiza mayeso
Pofufuza, magazi (seramu) otengedwa kuchokera mu mtsempha amagwiritsidwa ntchito. Ngati wodwala amamwa mankhwala (kuphatikiza kulera), siyani kumwa, kapena kumwa mankhwalawo musanamwe mankhwalawo. Sikulimbikitsidwa kuyesedwa ndi insulin mukatha kuchita masewera olimbitsa thupi komanso kumwa. Ngati maphunziro monga fluorography, x-ray, ultrasound adachitidwa, ndiye kuti magazi amayenera kuikidwa kaye mpaka tsiku lotsatira. Dokotala amalangiza wodwalayo momwe angakonzekerere bwino, ndikufotokozera cholinga cha phunzirolo. Kukonzekera kuli ndi malamulo awa:
- Kuyesedwa kwa insulin kuyenera kumwedwa pamimba yopanda kanthu, m'mawa kuyambira maola 8-10 (kutacha m'mawa alibe chakudya cham'mawa, amamwa madzi opanda madzi, opanda mpweya).
- Masiku awiri asanakacheze ku labotale, zakudya zopanda pake zimawonedwa - zakudya zamafuta sizikuperekedwa muzakudya.
- Mkati mwa maola 24, kupsinjika ndi kusokonezeka kwa malingaliro kumapewa.
- Maola 12 asanafike pang'onopang'ono musanadye zakudya zomwe zili ndi shuga wambiri ndi mafuta osavuta (confectionery, uchi, jamu, jams, buns okoma). Osamatsuka mano komanso kutafuna chingamu.
- Kwa maola 3-4 musamapume.
Pambuyo popereka magazi, wodwalayo amatha kusinthana ndi zakudya zake zamasiku onse ndikupitiliza kumwa mankhwala.
Kuphwanya malamulo okonzekera kungakhudze kudalirika kwa zotsatirazi, zomwe zimabweretsa zovuta komanso kuchedwa kwa chithandizo. Kulephera kutsatira zakudya (kudya zakudya zamafuta, zakudya zamafuta) kumatha kuwonetsa kuchuluka kwa insulin m'magazi. Ethanol wokhala ndi mowa amachepetsa njira za metabolic mthupi, amachepetsa shuga - pali chiwopsezo chosazindikira matenda a shuga pakapita nthawi. Pakusuta, kuchuluka mahomoni ambiri omwe amapondereza poizoni amapangidwa m'thupi la munthu. Kapangidwe ka magazi kamasintha, mamvekedwe ake amawonjezeka, omwe amasokoneza zotsatira za kafukufuku.
Kulemba zotsatira
Zotsatira zoyenera, maphunziro angapo amalembedwa mosiyanasiyana. Wodwala amapatsidwa zakumwa ndi shuga ndipo pambuyo pa maola 2 zizindikilo zimayendera. Izi zimakuthandizani kuti muzitha kudziwa za matendawo komanso kuti mupeze zosankha zolondola pazovuta za metabolic. Dokotala wodziwa bwino yekha ndi amene amalamula kuti ayambenso kubwezeretsa ndikutanthauzira kuyezetsa magazi. Mndandanda wazotsatira nthawi zambiri umawonetsa zizindikiro za m'badwo wa wodwalayo, monga momwe tikuwonera patebulo.
Zotsatira za tebulo lazotsatira
Gome la insulin ndi shuga
Zimayambitsa kusalinganika kwa mahomoni
Ngati kuyezetsa magazi kwa insulin kukuwonetsa kuchuluka kwa mahomoni, ndiye kuti izi zitha kuwonetsa kulephera kwa mahomoni, kumwa kwambiri zakudya zotsekemera ndi zamafuta, komanso kulimbitsa thupi. Kuwerengera kwa kusanthula kwa insulin ndi glucose kumakupatsani mwayi wofufuza matenda ashuga ndi matenda ena omwe amayamba chifukwa cha kulephera kwa mahomoni. Zisonyezo za insulin yotsika komanso shuga wamkulu zimawonetsa mtundu woyamba wa shuga. Mtundu 2 wa matenda ashuga, chotulukapo chake ndi insulin yayikulu ndi shuga wambiri. Kutupa kwa pancreatic kumawonetsa insulin yayikulu, komanso shuga wochepa.
Pali zinthu zina zomwe zotsatira za phunzirolo zikuwonetsa kuchuluka kwa mahomoni:
- ovarian cysts mwa akazi,
- onenepa kwambiri
- mavuto amanjenje
- kusokoneza chithokomiro,
- kulakwitsa kwa chimbudzi
- matenda a chiwindi.
Cholinga chachikulu cha kutsika kwa mahomoni ndi kusokonezeka kwa magazi mu kapamba. Zakudya zopatsa thanzi kwambiri, zomwe zimapezeka mkati mwake momwe, zimadzetsa kutupa kwa chimbudzi. Mitsempha yamagazi imapangika m'mitsempha yamagazi yomwe imasokoneza kuchuluka kwa magazi. Pancreatic minofu sililandira michere ndipo ntchito zake zimakhala zovuta. Insulin imapangidwa pang'ono, glucose samamwa, ndipo maselo amthupi ayamba kufa ndi njala.
Zinthu zomwe zimakhudza timadzi tating'onoting'ono ta magazi:
- vuto la autoimmune
- matenda opatsirana
- kuphwanya dongosolo la endocrine,
- matenda a mtima
- kumangokhala
- kuchita zolimbitsa thupi kwambiri.
Thupi laumunthu ndimapangidwe ovuta momwe insulin imasiyanitsira zochitika zonse za ziwalo. Moyo, mtundu wa zochita, mkhalidwe wosatetezeka ndi chilichonse chomwe munthu amadya, zimakhudza kuchuluka ndi mapangidwe a mahomoni. Ngati kwa nthawi yayitali insulin imachulukitsidwa kapena kuchepa, ndiye kuti njira zachilengedwe zachilengedwe zimasokonekera. Mikhalidwe imapangidwira ma pathologies monga chifuwa, kutupa, kunenepa kwambiri, khansa, mitsempha, kulephera kwa mtima.
Mutha kutenga mayeso a insulin m'chipatala chilichonse, koma kukonzekera sikofunikira, komanso matanthauzidwe olondola a zotsatira zake. Mulingo wabwinoko wa mahomoni umatheka pokhapokha ngati mufunika chithandizo chanthawi yake.