Momwe mungagwiritsire ntchito mankhwala blocktran?

Kuthamanga kwa magazi ndi vuto lofala kwambiri lomwe anthu ambiri amakumana nalo. Ndipo ndendende mwa zotere, odwala amamuika mankhwala "Blocktran". Malangizo ogwiritsira ntchito ndi osavuta, ndipo kuwunika kwa madokotala kumawonetsa kuti mankhwalawa amathandizadi kuthana ndi matenda oopsa.

Inde, odwala ambiri amafunafuna zowonjezereka zamankhwala. Kodi chida chili ndi chiyani? Kodi kugwiritsa ntchito mankhwalawa ndiwothandiza nthawi ziti? Kodi zoterezi zingachitike? Ndi ziti zomwe sizingatengedwe? Mayankho a mafunso awa ndiofunika.

Mankhwala "Blocktran": kapangidwe ndi mafotokozedwe a mawonekedwe omwe amasulidwe

Poyamba, ndikofunikira kumvetsetsa zofunikira. Mankhwala amapezeka mu mawonekedwe a biconvex wozungulira wozungulira mapiritsi. Pamwambapo adakutidwa ndi chipolopolo cha utoto wonyezimira wa pinki, nthawi zina ndimtundu wa lalanje. Pamtanda, mawonekedwe oyera amatha kuwoneka.

Mapiritsi a blocktran ali ndi potaziyamu wa losartan - ichi ndiye chinthu chachikulu chogwira ntchito. Kuphatikizika, kumene, kumakhala ndi zinthu zothandizira, makamaka, cellcrystalline cellulose, mbatata wowuma, lactose monohydrate, povidone, magnesium stearate, sodium carboxymethyl, colloidal silicon dioxide.

Popanga zokutira wamafilimu, zinthu monga Copovidone, polysorbate-80, hypromellose, titanium dioxide ndi utoto wachikasu ("dzuwa") zimagwiritsidwa ntchito.

Kodi mankhwalawo ali ndi katundu wotani?

Mankhwalawa ali ndi katundu wambiri yemwe amagwiritsidwa ntchito kwambiri pamankhwala amakono. Losartan ndi chinthu chomwe chimatchinga njira zowonjezera kuthamanga kwa magazi kwa diastoli ndi systolic. Chowonadi ndi chakuti gawo ili ndikusankha kosagwirizana ndi angiotensin II AT1 receptors.

Angiotensin II ndi vasoconstrictor. Amamangirira ku AT1 receptors, omwe ali gawo la minofu yambiri. Makamaka, zolandilira zoterezi zimapezeka m'maselo a mtima, impso, adrenal gland, minofu yosalala yomwe imapanga makoma amitsempha yamagazi. Angiotensin imapereka vasoconstriction ndipo imayambitsa kutulutsidwa kwa aldosterone.

Chidziwitso cha Pharmacokinetics

Malinga ndi zotsatira za kafukufuku, zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimatengedwa bwino, kulowa mkati mwa khoma lamatumbo kulowa m'magazi, ndikudutsa chiwindi. Zotsatira zake, mawonekedwe a carboxylated a yogwira ntchito ndipo ma metabolites angapo osagwira amapangidwa.

Zokhudza bioavailability wa mankhwala pafupifupi 33%. Kuchuluka kwa losartan m'magazi kumachitika pambuyo ola. Pambuyo pa maola 3-4, mulingo wa metabolite yogwira wa carbox wake nawonso umakwezeka. Palibe umboni kuti kudya mwanjira inayake kumakhudza mayamwidwe ndi kagayidwe ka mankhwala opangira mankhwala.

Zomwe zimagwira zimangokhala 99% zomangidwa ndi mapuloteni amwazi. M'maphunzirowa, zimatsimikiziridwa kuti pafupifupi 14% ya otayika amadzasinthidwa kukhala metabolite ya arbo-oxidized. Pafupifupi 42-43% ya metabolites amachotsedwa m'thupi ndi impso, komanso mkodzo. Zambiri zomwe zimagwira zimapangidwa pamodzi ndi ndulu m'matumbo ndikusiya chimbudzi ndi limodzi ndi ndowe.

Zowonetsa: Nditha kumwa mapiritsi liti?

Ndi munthawi ziti zomwe zikuyenera kugwiritsidwa ntchito ngati mankhwala a Blocktran? Zizindikiro zogwiritsidwa ntchito ndi motere:

• ochepa matenda oopsa (makamaka mitundu yayikulu ya matenda),
• lembani matenda ashuga a 2 a shuga (mankhwalawa amagwiritsidwa ntchito kuteteza mitsempha ya magazi a impso, komanso kuchepetsa kuchepa kwa kulephera kwa impso),
• Kulephera kwa mtima kwapafupipafupi (mankhwalawa amagwiritsidwa ntchito ngati zoletsa za ACE sizikupereka zotsatira zomwe zikufuna kapena wodwalayo alekerera ACE zoletsa),
• kuteteza kukula kwa mavuto a mtima ndi mitsempha ya magazi motsutsana ndi kuthamanga kwa matenda oopsa ndi kumanzere kwamitsempha yamagazi.

Malangizo ndi mlingo

Momwe mungamwe mankhwalawa "Blocktran"? Mlingo, komanso ndandanda yakuvomerezedwa, zimatsimikiziridwa payekhapayekha. Monga lamulo, odwala amapatsidwa koyamba 50 mg yogwira ntchito patsiku. Kuchuluka kwazinthu zambiri nthawi zambiri kumatha kuchitika pambuyo pa masabata 3-6 kuyambira pakuyamba chithandizo. Zikachitika kuti zotsatira zomwe mukufuna sizingatheke, mlingowo ungathe kuwonjezeka mpaka 100 mg patsiku, koma kokha kwakanthawi (ndiye kuchuluka kwa mankhwalawa tsiku ndi tsiku kumachepetsedwa).

Ngati wodwala akuchepa kuchuluka kwa magazi ozungulira (izi zimachitika, mwachitsanzo, motsutsana ndi kugwiritsidwa ntchito kwa okodzetsa), ndiye kuti tsiku ndi tsiku mlingo umachepetsedwa mpaka 25 mg wa losartan patsiku. Nthawi zina madokotala amalimbikitsa kugawa kuchuluka kwa tsiku ndi tsiku mu magawo awiri (mwachitsanzo, mapiritsi awiri okhala ndi 12,5 mg tsiku lililonse).

Mlingo womwewo (12,5 mg kamodzi patsiku) umaperekedwa kwa odwala omwe ali ndi vuto la mtima. Ngati vutoli palibe, ndiye kuti kuchuluka kwa mankhwalawo kumatha kuwonjezeka pang'onopang'ono. Ngati mapiritsi agwiritsidwa ntchito kuteteza impso ndi matenda ashuga, tsiku lililonse mlingo ndi 50-100 mg.

Pochiritsira, odwala amalangizidwa kuti asamale kapena asayendetse galimoto konse, achite zinthu zomwe zingakhale zoopsa, agwiritse ntchito njira zomwe zimafunikira kuchitapo kanthu mwachangu. Chowonadi ndi chakuti mapiritsi amakhudza zomwe zimachitika ponseponse - odwala nthawi zambiri amakhala ndi vuto lofooka, mavuto okhala ndi chidwi, komanso chizungulire komanso kusakwiya msanga kwa psychomotor.

Ndikofunika kukumbukiranso kuti musagwiritsidwe ntchito mankhwala osokoneza bongo "Blocktran". Malangizo ogwiritsa ntchito ali ndi chidziwitso chokha, chomwe chimangokhala chidziwitso chokha.

Kodi pali zotsutsana?

M'magawo onse, kodi blocktran angagwiritsidwe ntchito? Malangizo ogwiritsira ntchito ali ndi deta yomwe mapiritsi awa ali ndi zotsutsana zingapo:

• Mankhwalawa sanalembedwe kwa odwala omwe ali ndi hypersensitivity ku gawo lililonse la mapiritsi (onetsetsani kuti mwawona mndandanda wazinthu zomwe zimapezeka).
• Mankhwala osavomerezeka aana (chithandizo ndi chokhacho ngati wodwalayo ali ndi zaka zopitilira 18).
• Mankhwalawa "Blocktran" sagwiritsidwa ntchito kwa odwala panthawi yomwe ali ndi pakati, komanso panthawi yoyamwitsa.
• Mndandanda wa contraindication umaphatikizapo matenda monga glucose-galactose malabsorption syndrome, kuperewera kwa lactase, tsankho lactose.
• Mankhwalawa sanatchulidwe ngati wodwala ali ndi vuto lalikulu la chiwindi (palibe zotsatira zoyesedwa pankhaniyi).

Pali zotsutsana. Zikatero, kugwiritsa ntchito mapiritsi kumatheka, koma kumachitika kokha moyang'aniridwa ndi dokotala. Mndandanda wawo ukuphatikizapo:

• pambuyo podziika impso,
• aimpso mtsempha wamagazi,
• Hyperkalemia
• mitral ndi aortic stenosis,
• Mitundu ina ya kulephera kwa mtima, makamaka ngati zovuta za impso zilipo,
• hypertrophic cardiomyopathy,
• matenda a mtima
• kupezeka kwa mbiri ya wodwala ya angioedema,
• matenda amisala.

Ichi ndichifukwa chake ndikofunikira kufufuza mozama ndikudziwitsa adotolo za kupezeka kwa mavuto ena azaumoyo.

Zambiri pazomwe zimachitika komanso zovuta zina

Mankhwalawa amathandizadi kuthana ndi kuthamanga kwa magazi. Komabe, nthawi zonse pamakhala mwayi wina wobweretsa zovuta mutamwa mapiritsi a blocktran. Zotsatira zoyipa zitha kukhala zosiyana:

• Nthawi zina pamakhala zovuta zamagetsi. Odwala amadandaula za kupezeka kwa chizungulire, kupweteka kwa mutu. Kusokoneza kosiyanasiyana kwa kugona, kugona kosalekeza komanso kufooka usiku ndizothekanso.
• Nthawi zina, odwala amadandaula kuti akumva kupweteka kwamtima. Mwina chitukuko cha angina pectoris.
• Nthawi zina, mavuto amatuluka kuchokera ku mtima. Pali mwayi wokhala ndi hypotension (kutsika kwakukulu kwa kuthamanga kwa magazi, komwe kukuopseza moyo).
• Nthawi zonse pamakhala chiopsezo chokhudzana ndi kugaya chakudya. Anthu ena amadandaula za kupweteka kwam'mimba komwe kumachitika nthawi ndi nthawi. Kudzimbidwa.
• Zotsatira zoyipa zimaphatikizapo kufooka kwambiri, kutopa nthawi zonse, kuchepa kwa magwiridwe antchito, ndikupanga edema yolimbikira.
• Mwayi wokhala ndi zovuta zomwe sizingachitike sizikhudzidwa. Mwa odwala ena, redness, totupa limawonekera pakhungu, ndipo njirayi imaphatikizidwa ndi kuyabwa kwambiri ndi kutukusira kwa zofewa. Kugwedezeka kwa anaphylactic ndi angioedema ndizovuta zowopsa, koma, mwamwayi, sizomwe zimalembedwa motsutsana ndi maziko a chithandizo chotere.
• Nthawi zina, paresthesias amakula.
• Pali chiopsezo cha kuchepa magazi. Ichi ndichifukwa chake odwala amalangizidwa kuti nthawi ndi nthawi azichita mayeso ndi kukayezetsa.

• Mndandanda wazotsatira zimaphatikizira kuzungulira kwa ubongo.
• Kuchepetsa kwambiri kuthamanga kwa magazi kungachititse kuti musamaiwale.
• Mwina kuwoneka kutsokomola, kufupika ndi zovuta zina kuchokera ku kupuma.
• Therapy nthawi zina kumabweretsa vuto laimpso. Pali mwayi wopeza kulephera kwa impso.
• Zotsatira zina zoyipa zimaphatikizapo chiwindi ndi chiwindi china. Nthawi zina, kapamba amayamba pakumwa.
• Mwina chitukuko cha arthralgia, myalgia.
• Mwa odwala amuna, kumwa mankhwalawa kumatha kubweretsa kusokonekera kwa erectile, kusakhalitsa kwakanthawi.
• Pali mwayi wokhala ndi migraines, kukula kwamayiko okhumudwitsa.

Mpaka pano, palibe deta pa bongo. Amakhulupirira kuti kumwa mankhwala waukulu kwambiri kumawonjezera kuwonetsa. Zikatero, munthuyo ayenera kupita kuchipatala. Syndrome dalili ndi kukakamiza diuresis amachitika. Hemodialysis pankhaniyi ilibe kufunika.

Zambiri pazamankhwala pa mimba ndi mkaka wa m`mawere

Monga tanena kale, panthawi yoyembekezera, mankhwalawa "Blocktran" sayenera kugwiritsidwa ntchito. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimasokoneza kukula kwa mluza. Malinga ndi kafukufuku, kugwiritsa ntchito mankhwalawa munthawi yachiwiri ndi / kapena kachitatu kumakhala kovutitsa kakulidwe ka impso. Kuphatikiza apo, pamankhwala, mwayi wa kufa kwa intrauterine ukuwonjezeka. Mavuto omwe angakhalepo akuphatikizaponso kulephera kwa mafupa a mwana, komanso kupindika kwapang'onopang'ono kwa mapapu a fetal. Mwina chitukuko cha aimpso kulephera komanso ochepa matenda oopsa mwa akhanda.

Ngati ndizosatheka kupewa chithandizo chotere, wodwalayo ayenera kudziwitsidwa za zovuta zomwe zingachitike. Mayi woyembekezera ayenera kuyang'aniridwa ndi dokotala, kumayesedwa, ndikupimidwa pafupipafupi. Mpaka pano, palibe chidziwitso choti losartan kapena metabolites yake yogwira ntchito amawachotsa limodzi mkaka wamawere. Komabe, odwala amawalangizidwabe kuti ayime kudya kwa nthawi yayitali. Chowonadi ndi chakuti zinthu zomwe zimagwira zimatha kusokoneza thupi la mwana.

Kuchita ndi mankhwala ena

Panthawi yodziwikirayi, ndikofunikira kudziwitsa adotolo za mankhwala onse omwe amamwa, chifukwa pali mwayi wokhala nawo mogwirizana ndi mankhwalawa "Blocktran".

Malangizo ogwiritsira ntchito ali ndi chidziwitso chofunikira:

• Mankhwala sayenera kumwedwa limodzi ndi Aliskiren, popeza pali ngozi yochepetsetsa kwambiri magazi ndi kuwonongeka kwakukulu kwa impso.
• Sitikulimbikitsidwa kuphatikiza mankhwalawa ndi ACE inhibitors. Pali mwayi wokhala ndi hyperkalemia, kupweteka kwa impso, mitundu yayikulu ya hypotension.
• Simuyenera kuphatikiza mankhwalawa ndi mankhwala osapweteka a anti-steroidal, chifukwa izi zitha kufooketsa mphamvu ya antihypertensive, komanso kuyambitsa kuwoneka kwa zovuta zingapo za dongosolo la ma excretory.
• Simungathe kumwa mankhwala ndikukonzekera kwa potaziyamu, chifukwa nthawi zonse pamakhala chiopsezo chokhala ndi hyperkalemia. Kugwiritsa ntchito potaziyamu posungira mauretics kungayambitse zotsatira zomwezo.
• Ndi munthawi yomweyo makonzedwe a sympatholytics ndi mankhwala ena a antihypertensive, kulimbikitsana kwamphamvu kungathandize.
• Ngati mugwiritsa ntchito "Blocktran" ndi fluconazole, ndiye kuti mwina angathe kutsika kwa antihypertensive. Kuyendetsa munthawi yomweyo ndi Rifampicin kumatha kubweretsanso zomwezo.
• Ngati wodwala amatenga waukulu Mlingo okodzetsa, ndiye kuti magazi ozungulira amachepetsa, omwe angayambitse kukula kwa chizindikiro cha hypotension.

Kodi mapiritsi ndi angati?

Mukudziwa kale momwe mankhwalawa amalembedwera komanso momwe mankhwala a Blocktran amakhudzira thupi. Mtengo ndi chinthu china chofunikira chomwe odwala ambiri amachita nacho chidwi. Zachidziwikire, ndizovuta kuwonetsa nambala yeniyeni, chifukwa zambiri zimatengera ndondomeko zachuma zamankhwala, wopanga ndi wogulitsa. Nanga mtengo wa Blocktran umawononga ndalama zingati? Mtengo wa phukusi la mapiritsi 30 ndi mulingo wachilengedwe wa 12.5 mg ndi pafupifupi ma ruble 150. Kwa manambala omwewo, koma ndi mlingo wa 50 mg, muyenera kulipira ma ruble pafupifupi 170-190. Phukusi la mapiritsi 60 lidzawononga 300 rub50 rubles (50 mg).

Mankhwala "Blocktran": analogues ndi m'malo

Tsoka ilo, sizotheka kuti kugwiritsa ntchito mankhwalawa ndizotheka. Kodi ndizotheka m'malo mwa mankhwalawa "Blocktran" ndi china chake? Mndandanda wa mankhwalawo, mwachidziwikire, ulipo, ndipo kusankha kwawo ndikokulira. Ngati tizingolankhula za mtundu womwewo wa mankhwala, ndiye "Lozap", "Lozartan" ndi "Vazotens" amatengedwa kuti ndi othandiza. Mmalo wabwino ndi Kozzar.

Lorista, Presartan ndi mankhwala abwino a antihypertensive omwe amagwiritsidwa ntchito kwambiri ngati mankhwala amakono. Inde, ndizosatheka kugwiritsa ntchito mankhwalawa popanda chilolezo. Ndi okhawo omwe amapezeka ndi omwe amatha kusankha mankhwala othandiza komanso otetezeka.

Ndemanga za Mankhwala

Muzochita zamakono zamankhwala, nthawi zambiri ndi matenda oopsa, ndi mankhwala a blocktran omwe amagwiritsidwa ntchito. Umboni ndi chidziwitso chofunikira chomwe tiyenera kudziwa.

Madokotala nthawi zambiri amapereka mankhwala ngati wodwala. Malinga ndi zotsatira za maphunziro owerengera, Blocktran imathandizadi ndikapanikizika. Kutsika kwa zizindikirozi kumachitika mwachangu, ndipo zotsatira za mapiritsi zimatha nthawi yayitali. Njira zochiritsira ndizosavuta. Ubwino wosakayikira wa mankhwalawa umaphatikizapo mtengo wake wotsika - ma analogi ambiri amakhala okwera mtengo kwambiri.

Ponena za malingaliro oyipa, odwala ena amawonetsa kuwoneka kwa zoyipa. Nthawi zambiri, chithandizo chamankhwala chimagwirizanitsidwa ndi kutopa kwambiri, mapangidwe otupa pakhungu, kuyabwa kwambiri.Nthawi zina (monga lamulo, pakudzipaka nokha kuchuluka kwa mankhwalawa), mapiritsi amachititsa kugwa kwambiri kwa magazi.

Kutulutsa mafomu ndi kapangidwe kake

Mankhwalawa amapangidwa molimba. Chofunikira chachikulu pakupanga ndi potaziyamu losartan. Kutulutsa kwake piritsi limodzi ndi 50 mg. Zinthu zina zosagwira:

• lactose monohydrate,
• cellcrystalline mapadi,
• wowuma mbatata
• povidone
• magnesium wakuba,
• sodium carboxymethyl wowuma,
• silicon dioxide colloidal.

Mankhwalawa amapangidwa molimba.

Zotsatira za pharmacological

Ntchito yayikulu ya mankhwalawa ndi kuthekera kwachulukitsa magazi. Izi zitha kuperekedwa popewa kupezeka kwa zochitika zolimbitsa thupi zomwe zimayambitsa ndikumanga kwa agonists ndi angiotensin II receptors. Zomwe zimagwiritsidwa ntchito ku Blocktran sizikhudza enzyme kinase II, yomwe imathandizira kuti bradykinin (peptide chifukwa chomwe ziwiya zimakula, kuchepa kwa magazi kukhale).

Kuphatikiza apo, izi sizikhudza ma receptor angapo (mahomoni, ma ion njira) omwe amathandizira kukulitsa kutupa ndi zotsatira zina. Mothandizidwa ndi losartan, kusintha kwa kuchuluka kwa adrenaline, aldosterone m'mwazi amadziwika. Kuphatikiza apo, mankhwalawa amayimira gulu la okodzetsa - amalimbikitsa kuchepa kwa madzi m'thupi. Chifukwa cha mankhwalawa, mwayi wokhala ndi hypertrophy ya myocardial umachepetsedwa, odwala omwe ali ndi vuto losakwanira la mtima amalolera zochitika zolimbitsa thupi.

Ntchito yayikulu ya mankhwalawa ndi kuthekera kwachulukitsa magazi.

Pharmacokinetics

Ubwino wa chida ichi ndi monga kuyamwa mwachangu. Komabe, bioavailability wake ndi wotsika kwambiri - 33%. Mulingo wofunikira kwambiri umatheka pambuyo pa ola limodzi. Pakusintha kwa chinthu chachikulu chogwira ntchito, metabolite yogwira imamasulidwa. Peak ya chithandizo chokwanira kwambiri imatheka pambuyo pa maola 3-4. Mankhwala amalowa m'madzi a m'magazi, chizindikiro cha mapuloteni ake - 99%.

Losartan sasintha mu maola 1-2. Metabolite imachoka m'thupi pambuyo pa maola 6-9. Mankhwala ambiri (60%) amawachotsa m'matumbo, ena onse - pokodza. Kudzera m'maphunziro azachipatala, zidapezeka kuti kuchuluka kwa gawo lalikulu m'madzi a m'magazi kumawonjezeka. Mphamvu yayitali kwambiri ya antihypertensive imaperekedwa pambuyo pa masabata 3-6.

Pambuyo pa limodzi mlingo, zotsatira zofunika pa mankhwala zimapezeka pambuyo maola ochepa. Masautso a losartan amayamba kuchepa. Zimatengera tsiku limodzi kuti muchotse zinthu izi. Pachifukwa ichi, kuti mupeze zofunikira zochizira, ndikofunikira kumwa mankhwala pafupipafupi, kutsatira chiwembu.

Mankhwala ambiri (60%) amawachotsa m'matumbo, ena onse - pokodza.

Zizindikiro zogwiritsidwa ntchito

Wothandizila amamulembera matenda oopsa. Zizindikiro zina zogwiritsa ntchito Blocktran:

• kusakwanira kwa ntchito yamtima mu mawonekedwe osakhazikika, bola ngati chithandizo cham'mbuyomu ndi ACE inhibitors sichinapereke zotsatira zomwe zingafunikire, komanso ngati milandu yomwe ACE inhibitors imathandizira kukulitsa zotsatira zoyipa ndipo palibe mwayi wowatenga.
• kukhalabe impso ntchito mu mtundu 2 matenda a shuga, kuchepetsa mphamvu ya kukula kwa kupanda kwa thupilo.

Chifukwa cha mankhwalawa, pali kuchepa kwa kupezeka kwa ubale pakati pa matenda a mtima ndi kufa kwake.

Contraindication

Zoletsa kugwiritsa ntchito Blocktran:

• Hypersensitivity ku zilizonse za mankhwala,
• angapo matenda a chibadwa chikhalidwe: lactose tsankho, shuga-galactose malabsorption syndrome, kuchepa kwa lactase.

Wothandizila amamulembera matenda oopsa.

Ndi chisamaliro

Ngati matenda a coronary, impso, mtima kapena chiwindi kulephera (stenosis ya mitsempha ya impso, hyperkalemia, etc.) atapezeka, ndikofunikira kugwiritsa ntchito mankhwalawa moyang'aniridwa ndi dokotala, kuyang'anira thupi mosamala. Pakachitika zovuta, njira ya mankhwalawa imatha kusokonezedwa. Malangizowa akukhudzidwa ndi milandu yomwe angioedema yapanga kapena kuchuluka kwa magazi kwachepetsedwa.

Momwe mungatenge Blocktran

Mlingo wa tsiku ndi tsiku ndi piritsi limodzi lokhala ndi mphamvu ya 50 mg. Ndi matenda oopsa osagwirizana, ndizovomerezeka kuwonjezera kuchuluka uku mpaka 100 mg patsiku. Imagawidwa mu 2 Mlingo kapena kumwa kamodzi patsiku. Muli matenda osiyanasiyana, mankhwalawa tsiku lililonse amakhala ochepa:

• kulephera kwa mtima - 0,0125 g,
• Ndi munthawi yomweyo mankhwala okodzetsa, mankhwala zotchulidwa muyezo osapitirira 0,025 g.

Mwambiri, mankhwalawa amatengedwa sabata limodzi, ndiye kuti mlingo umakulitsidwa pang'ono. Izi ziyenera kupitilizidwa mpaka malire a tsiku lililonse a 50 mg afike.

Mlingo wa tsiku ndi tsiku ndi piritsi limodzi lokhala ndi mphamvu ya 50 mg.

Zotsatira zoyipa za Blocktran

Nthawi zambiri, mankhwalawa amalekeredwa bwino. Ngati zizindikiro zoyipa zikuwoneka, nthawi zambiri zimazimiririka zokha, pomwe palibe chifukwa choletsa mankhwalawo. Zotsatira zoyipa za ziwalo zam'maganizo zimatha kukhazikika: kuwonongeka kwamawonekedwe, tinnitus, maso oyaka, vertigo.

Pakati mantha dongosolo

Mutu, chizungulire, kukhumudwa m'maganizo, limodzi ndi kumva kutentha. Kupendekera, kusokera m'malingaliro (kupsinjika, kuwopsezedwa ndi nkhawa ndi nkhawa), kusokonezeka kwa kugona (kugona kapena kugona tulo), kukomoka, kunjenjemera kwa malekezero, kuchepa kwa chidwi, kukhumudwa kukumbukira, kusokonezeka kwa malingaliro komanso kukhudzika zimadziwikanso.

Pambuyo kumwa mankhwalawa, pamatha kupweteka m'mimba.

Kuchokera pamtima

AV block (2 degrees), myocardial infarction, hypotension yamtundu wina (ochepa kapena orthostatic), kupweteka pachifuwa ndi vasculitis. Ambiri a zochitika zamatenda zimadziwika, limodzi ndi kuphwanya mtima: mtima wa angina pectoris, tachycardia, bradycardia.

Kuchokera pamtima.

Urticaria, kupuma movutikira chifukwa cha kutukusira kwa kupuma kwa thirakiti, anaphylactic reaction.

Malangizo apadera

Asanayambe chithandizo, odwala amawonetsedwa kutopa. Ndikofunikira kuwunika pafupipafupi potaziyamu.

Ngati mumwa mankhwalawa panthawi yapakati (mu 2 ndi 3 trimester), chiopsezo cha kufa kwa mwana wosabadwa ndi wakhanda chimawonjezeka. Zoopsa zingapo nthawi zambiri zimawonekera mwa ana.

Pophwanya ufulu wamagetsi wamagetsi, mwayi wokhala ndi hypotension ukuwonjezeka.

Ngati mumwa mankhwalawa panthawi yapakati (mu 2 ndi 3 trimester), chiopsezo cha kufa kwa fetal chimawonjezeka.

Ndi matenda a shuga a 2, hyperkalemia imatha kuchitika.

Ngati wodwala wapezeka ndi hyperaldosteronism yoyamba, mankhwalawo saikidwa, chifukwa pankhaniyi zotsatira zabwino sizingatheke.

Blocktran bongo

• kuchepa kwamphamvu kwa kuthamanga kwa magazi,
• tachycardia
• bradycardia.

Mankhwala osokoneza bongo a Blocktran amachititsa tachycardia.

Njira zochizira zomwe zalimbikitsidwa: diuresis, mankhwala othandizira kuchepetsa mphamvu kapena kuthetseratu kuwonetsera koyipa. Hemodialysis pankhaniyi siyothandiza.

Kuchita ndi mankhwala ena

Sizoletsedwa kumwa mankhwalawo nthawi yomweyo ndi aliskiren ndi mankhwala othandizira, ngati wodwala wapezeka ndi matenda a shuga kapena kulephera kwa aimpso.

Sizoletsedwa kukonzekera zomwe zimakhala ndi potaziyamu panthawi ya mankhwala ndi Blocktran.

Palibe zoyipa zomwe zimagwiritsidwa ntchito ndi munthawi yomweyo kugwiritsa ntchito mankhwalawa pogwiritsa ntchito hydrochlorothiazide, warfarin, digoxin, cimetidine, phenobarbital.

Mothandizidwa ndi Rifampicin, kuchepa kwa kugwiritsidwa ntchito kwa zinthu zomwe zikuchitika mu blocktran kumadziwika. Fluconazole amachitanso chimodzimodzi.

Sizoletsedwa kukonzekera zomwe zimakhala ndi potaziyamu panthawi ya mankhwala ndi Blocktran.

Losartan amachepetsa ndende ya lithiamu.

Mothandizidwa ndi NSAIDs, mphamvu ya mankhwala omwe amafunsidwa amachepa.

Ndi matenda a shuga a mellitus ndi kulephera kwa aimpso, ndizoletsedwa kugwiritsa ntchito aliskiren ndi mankhwala ozikidwa pompopompo

Kuyenderana ndi mowa

The yogwira pophika mankhwala amafunsidwa zimabweretsa zovuta ngati ntchito imodzi ndi zakumwa zoledzeretsa.

• Losartan
• Losartan ovomerezeka
• Lorista
• Lozarel
• Presartan
• Blocktran GT.

Ndizovomerezeka kuganizira mankhwala aku Russia (Losartan and Losartan Canon) ndi analoques achilendo. Ogwiritsa ntchito ambiri amakonda mankhwala opezeka m'mapiritsi, chifukwa ndiwosavuta kugwiritsa ntchito: palibe chifukwa chotsatira malamulo aukhondo pakugwiritsira ntchito mankhwalawa, palibe chifukwa chofunikira pakulamulira, monga momwe zilili ndi yankho. Mapiritsi amatha kuthandizidwa ndi inu, koma mlingo umawerengedwa ngati malonda anu agwiritsidwa ntchito mwanjira ina.

Ndemanga za blocktran

Kuyesedwa kwa akatswiri ndi ogula ndi njira yofunikira posankha mankhwala. Imagwiritsidwa ntchito limodzi ndi zomwe mankhwalawo amapanga.

Ivan Andreevich, katswiri wamtima, Kirov

Mankhwalawa amaletsa ma receptor ena okha, ndipo samakhudza kayendedwe kazinthu zosiyanasiyana zomwe zimatsimikizira kuyendetsa bwino kwa thupi. Mukakhazikitsa, mawonekedwe a wodwalayo komanso kupezeka kwa matenda omwe amakumana nawo amakumbukiridwa, popeza Blocktran ili ndi zotsutsana zambiri.

Anna, wazaka 39, Barnaul

Ndili ndi kuthamanga kwa magazi m'moyo wanga. Ndikudzipulumutsa ndekha ndi chida ichi. Ndipo pamavuto, ndi mankhwala okhawo omwe amawathandiza. Nditathetsa chiwonetsero chachikulu cha matenda oopsa, ndikupitiliza kumwa ma piritsi kuti ndikhale ndi nkhawa nthawi yayitali. Zotsatira zake ndi mankhwalawa ndi zabwino kwambiri.

Victor, wazaka 51, Khabarovsk

Ndili ndi matenda ashuga, motero ndikugwiritsa ntchito mankhwalawa mosamala. Mapiritsi amatha kuchepetsa kuthamanga kwa magazi ngati mutatenga mlingo wopitilira womwe umalimbikitsa. Koma pakadali pano sindinapeze njira ina pakati pa mankhwala omwe ali ndi mphamvu zambiri, ndimagwiritsa ntchito Blocktran. Zoyesera komanso zamafuta othandizira, koma samapereka zotsatira zomwe akufuna.