Ofloxin - malangizo, ntchito, mawonekedwe, kutulutsira, Mlingo, analogi ndi mtengo

• Mapiritsi okhala ndi filimu: pafupifupi oyera kapena oyera, ozungulira biconvex, olembedwa "200" mbali imodzi ndikugawa chizindikiro mbali inayo, mawonekedwe mkati mwake panthawi yopuma ndi yoyera kapena pafupifupi yoyera (m'matumba: 7 ma PC., Per makatoni okhala ndi matuza 2, ma PC 10., pamatoni ojambula 1 kapena 2 matuza),
• Njira yothetsera kulowetsedwa: madzi owoneka bwino, opepuka wonyezimira wonyezimira (100 ml m'mabotolo osawoneka ngati galasi, botolo limodzi mu mtolo wa makatoni).

Bokosi la makatoni lilinso ndi malangizo ogwiritsira ntchito Ofloxin.

Yogwira pophika - ofloxacin:

• 1 piritsi - 0,2 g
• 1 botolo la yankho - 0,2 g.

• Mapale: povidone 25, lactose monohydrate, crospovidone, wowuma chimanga, magnesium stearate, poloxamer, talc,
• Yankho: disodium edetate dihydrate, yokhazikika ya hydrochloric acid, sodium chloride, madzi a jekeseni.

Kuphatikiza apo, momwe kapangidwe ka chipolopolo chimakhalira: macrogol 6000, hypromellose 2910/5, titanium dioxide, talc.

Mankhwala

Chothandizira cha Ofloxin, chaloloacacin, ndichinthu chodabwitsa kwambiri cha antibacterial chomwe chimagwira bacteria. Zili pagulu la fluoroquinolones. Kapangidwe ka kachitidwe kake kamachitika chifukwa cha kuthekera kotchinga kwa gyrase ya DNA ya tizilombo tating'onoting'ono - ma enzyme yomwe imakhudzana ndi njira zolembedwa komanso kusindikizanso mabakiteriya a deoxyribonucleic acid (DNA).

Ofloxacin ali ndi antibacterial zochita motsutsana ndi gram-positive ndi gram-hasi tizilombo, monga Proteus spp., Enterobacteriaceae (Citrobacter spp., Enterobacter spp., Escherichia coli, Klebsiella spp., Providencia spp., Salmonella spp., Shigella spp. Yersinia spp.). Ndi polimbana matenda oyamba ndi mabakiteriya zotsatirazi: Acinetobacter spp, Branhamella catarrhalis, Brucella melitensis, Campylobacter spp, Gardnerella vaginalis, Haemophilus influenzae, Haemophilus ducreyi, Helicobacter pylori, Neisseria meningitidis, Neisseria gonorrhoeae, Pasteurella multocida, Pseudomonas aeruginosa, Pseudomonas spp, ... Vibrio spp.

Ofloxin amagwiritsidwanso ntchito mu staphylococci, kuphatikiza tizilombo ta penicillinase komanso methicillin toyambitsa mabakiteriya osiyanasiyana (Chlamydia trachomatis, Chlamydia pneumoniae, Mycobacterium TB, Mycobacterium leprae, Mycoplasma pneumoniae, Ureaplasma urealy.

Ofloxacin ali ndi mphamvu yochepa yolimbana ndi matenda omwe amayamba chifukwa cha gulu A, B ndi C. streptococci.

Anaerobes (kupatula Clostridium perfringens) ndi wothandizila wa causative wa syphilis amagwirizana ndi Ofloxin.

Pharmacokinetics

Pambuyo pakukonzekera kwa Ofloxin, ofloxacin imatengedwa mwachangu kuchokera m'mimba. Kuzindikira kwakukulu m'magazi (Cmax) kumafika mkati mwa mphindi 60-120.

Ndi mapuloteni a plasma, 25% imamanga. The bioavailability ndi 96-100%. Imalowa bwino m'matupi onse, omwe amafalitsidwa m'madzi onse amthupi, kuphatikizanso chingwe cha msana. M'malo mwakuya kwambiri, amatsimikiza mu bile ndi ndulu. Imalowa mkatikati mwa chotchinga ndi mkaka wa m'mawere.

Amapangidwa kuti ofloxacin-N-oxide ndi ofloxacin-desmethyl. Kutha kwa theka-moyo ndi maola 5-8, kumatha kuwonjezeka kwambiri ngati kulephera kwa impso - mpaka maola 15- 60. Pafupifupi 80% ya mlingo wolandilidwa umatsitsidwa ndi impso ndi secretion wa tubular ndi kusefera, pomwe osaposa 5% ndi metabolites, ena onse ndi mankhwala osasinthika. Wina 4-8% ya mankhwalawa amachokera m'matumbo. Excretion imachepetsa odwala omwe ali ndi chiwindi chachikulu.

Chilolezo chonse ndi 214 ml / min, aimpso - 173 ml / min. Pazinthu zochepa, amathandizidwa pa hemodialysis. Hafu ya moyo pa hemodialysis ndi maola 8-12, ndi peritoneal dialysis - maola 22.

Pambuyo mtsempha wa magazi makonzedwe a 200 mg waloxine, Cmax ofloxacin amawonedwa pambuyo pafupifupi ola 1. Kufanana kwa mankhwala kumachitika pambuyo pa kulowetsedwa kwa 4 infusions. Kuchotsa hafu ya moyo ndi maola 6-7.

Zizindikiro zogwiritsidwa ntchito

Kugwiritsa ntchito Ofloxin akuwonetsedwa pa matenda a matenda opatsirana komanso otupa omwe amayambitsidwa ndi tizilombo tating'onoting'ono tokhudza mankhwala:

• Bronchitis, chibayo,
• Meningitis
• Sinusitis, atitis media, pharyngitis, laryngitis,
• Matenda ophatikizika ndi mafupa
• Matenda opatsirana pakhungu, minofu yofewa,
• Matenda opatsirana komanso otupa am'mimba, thirakiti la biliary ndi ziwalo zina zam'mimba.
• Endometritis, oophoritis, salpingitis, cervicitis, prostatitis, parametritis,
• Pyelonephritis, cystitis, urethritis,
• Gonorrhea
• Matenda amtunduwu (orchitis, colpitis, epididymitis),
• Chlamydia

Odwala ndi neutropenia ndi ena opuwala chitetezo Ofloxin ndi zotchulidwa kupewa matenda.

Kuphatikiza apo, yankho limagwiritsidwa ntchito pochiza septicemia.

Contraindication

• Khunyu (kuphatikizapo mbiri yamankhwala),
• Glucose-6-phosphate dehydrogenase akusowa,
• Kuchepa kwambiri kwa gawo logwedezeka la ubongo, kuphatikizira mikhalidwe pambuyo povulala, kuvulala koopsa m'mitsempha kapena kutupa kwamkati mwa dongosolo lamanjenje (CNS),
• Osakwana zaka 18
• Nthawi yokhala ndi pakati komanso yoyamwitsa,
• Hypersensitivity mankhwala.

Mochenjera, tikulimbikitsidwa kuti Ofloxin apatsidwe odwala omwe ali ndi vuto la chithokomiro chamchiberekero, chizindikiritso cha mbiri ya ngozi ya m'magazi, kuwonongeka kwa organic pakukhumudwa, komanso kulephera kwaimpso.

Kuphatikiza apo, mapiritsi a Ofloxin amapikisidwa kwa odwala omwe amawonongeka pambuyo pa quinolone yapita, komanso mosamala pakukulitsa pa QT electrocardiography yokhazikika.

Mapiritsi okhala ndi mafilimu

Mapiritsi a Ofloxin amatengedwa musanadye kapena pakudya, pakamwa, kumeza lonse ndikumwa madzi ambiri.

Dokotala amafotokozera kuchuluka kwa mankhwalawa komanso kutalika kwa mankhwalawa pozindikira momwe wodwalayo alili, mtundu wake wa matenda komanso magwiridwe antchito a chiwindi ndi impso.

Mlingo wovomerezeka tsiku lililonse wa Ofloxin ukhoza kukhala 0,2 mpaka 0,6 ga, kotero, mlingo wofikira 0,4 ga tsiku lililonse amatengedwa nthawi imodzi, makamaka m'mawa, ndipo mlingo wopitilira 0.4 g umagawika m'magawo awiri ofanana ndipo umatengedwa pakanthawi kofanana nthawi 2 pa tsiku. Kutalika kwa mankhwalawa ndi masiku 7-10.

Munthawi yayitali matenda opatsirana kapena wodwala akayamba kunenepa kwambiri, mlingo wa tsiku ndi tsiku umatha kuchuluka mpaka 0,8 g.

Mankhwalawa zosavuta matenda a m'munsi kwamikodzo thirakiti, 0,2 ga tsiku zotchulidwa 3-5 masiku, ndi chinzonono - 0,4 g kamodzi.

Mankhwalawa koyamba ndi Ofloxin mu njira ya kulowetsedwa pambuyo kusintha kwa mkhalidwe wa wodwalayo akhoza kupitiliza mwa kumwa mapiritsi omwewo.

Kugwiritsa ntchito limodzi ndi ma antacid ndikutsutsana.

Kulowetsedwa njira

Ofloxin yothetsera imayendetsedwa.

Mlingo wa mankhwala payekhapayekha, poganizira kuopsa ndi kutengera kwa matenda, chidwi cha tizilombo tosiyanasiyana, mkhalidwe wa odwala, impso ndi chiwindi.

Chithandizo chimayamba ndi jekeseni imodzi yovomerezeka ya 0,2 ga mankhwala kwa maola 0,5-1. Pambuyo pakuwongolera mkhalidwe wa wodwalayo, amawasamutsira kuyamwa mapiritsi amodzimodzi tsiku lililonse.

Dosing Ofloxin Yosangalatsa:

• Matenda amitsempha yam'mimba: 0,1 ga 1-2 pa tsiku,
• Matenda a ziwalo zoberekera ndi impso: 0.1-0.2 g 2 pa tsiku,
• Matenda a kupuma thirakiti, khutu, mmero ndi mphuno (pharyngitis, sinusitis, otitis media, laryngitis), minofu yofewa ndi khungu, mafupa ndi mafupa, matumbo am'mimba, matenda a septic: 0,2 ga 2 pa tsiku, kuti mupeze njira yothandizira, imatha kuwonjezeka mpaka 0,4 g kawiri pa tsiku,
• Kupewera kwa matenda omwe amadziwika kuti kuchepa kwa chitetezo chokwanira: 0,2 g, wothira 5% shuga yankho, nthawi ya kulowetsedwa - maola 0,5 (sakanizani mavutowa musanayambe makonzedwe).

Mlingo umodzi wa Ofloxin wochizira odwala omwe amathandizira aimpso kuwonongeka (creatinine chilolezo (CC) 50-20 ml / min) akuyenera kufanana ndi 1/2 mwa avareji omwe akutsimikiziridwa ndikugwiritsidwa ntchito kawiri pa tsiku. Ndi CC zosakwana 20 ml / min, muyeso umodzi wa 0.2 g umayikidwa, ndiye - tsiku lina lililonse, 0,1 g patsiku.

Ndi hemodialysis ndi peritoneal dialysis - 0,1 ga kamodzi patsiku.

Kwa odwala omwe ali ndi vuto la chiwindi, mlingo wa tsiku ndi tsiku sayenera kupitirira 0,4 g.

Zotsatira zoyipa

• Matumbo a pakhungu: nseru, kusanza, matenda am'mimba, kutsegula m'mimba, kupweteka kwam'mimba, kupweteka kwam'mimba, pseudomembranous enterocolitis, kuchuluka kwa michere ya chiwindi, cholestatic jaundice, hyperbilirubinemia,
• Mtima dongosolo: kutsitsa magazi (BP), vasculitis, tachycardia, kugwa,
• Machitidwe amanjenje: mutu, kukokana, kusatetemera mayendedwe, chizungulire, kunjenjemera, kugwedezeka mwamphamvu ndi kuchuluka kwa malekezero, kuchuluka kwazovuta zam'maganizo, kulota kwakukulu ndi / kapena zochititsa mantha usiku, nkhawa, malingaliro amisala, phobias, kuwonjezeka, kukhumudwa, kuyerekezera zinthu, kusokonezeka,
• Hematopoietic dongosolo: kuchepa magazi, agranulocytosis, leukopenia, pancytopenia, thrombocytopenia, aplastic ndi hemolytic anemia,
• Zazinthu zomveka: kununkhika, kununkhira, kumva, bwino, diplopia, kuzindikira kwa khungu.
• Matenda a minofu ndi mafupa: tendosynovitis, myalgia, tendonitis, arthralgia, kupindika kwa tendon,
• Kwamikodzo dongosolo: mkhutu aimpso ntchito, kuchuluka magazi urea ndende, pachimake interstitial nephritis, hypercreatininemia,
• Dermatological zimachitika: petechiae (ma hemorrhages), a hemorrhagic dermatitis, photosensitivity, papular zidzolo,
• Thupi lawo siligwirizana: kutentha thupi, kuyabwa, zotupa pakhungu, urtaria, chifuwa, chifuwa cha Quincke, matenda a Stevens-Johnson, bronchospasm, erythema multiforme, matenda a Lyell, anaphylactic.
• Zina: superinfection, dysbiosis, omwe ali ndi matenda ashuga - hypoglycemia, vaginitis.

Kuphatikiza apo, Ofloxin imatha kuyambitsa mavuto amodzi mwa mitundu ya mankhwalawa:

• Mapale: kuchokera m'matumbo a chimbudzi - hepatitis, musculoskeletal system - kufooka kwa minofu, rhabdomyolysis,
• Njira yothetsera kulowetsedwa: zimachitika jekeseni malo opweteka, redness, thrombophlebitis.

Malangizo apadera

Ndi chibayo cha pneumococcal ndi tonsillitis yacute, Ofloxin sikuti akuyenera kugwiritsidwa ntchito.

Kutalika kwa mankhwala ndi mankhwala sayenera upambana 2 miyezi.

Wodwala ayenera kupewa kuyatsidwa ndi kuwala kwamphamvu ndi dzuwa.

Ngati zizindikiro za mavuto amkati mwa dongosolo lamkati, pseudomembranous colitis, chitukuko cha matupi awo sagwirizana, mankhwala ayenera kusiyidwa. Zochizira zasayansi-pseudomembranous colitis, makonzedwe amkamwa a vancomycin ndi metronidazole amasonyezedwa.

Kugwiritsidwa ntchito kwa Ofloxin nthawi zina kumayambitsa kupangika kwa tendonitis, komwe kumatha kuyambitsa kupindika kwa tendon (Achilles tendon), nthawi zambiri mwa odwala okalamba. Chifukwa chake, tendinitis ikachitika, ndikofunikira kulimbitsa tendon ya Achilles ndikupeza kufunsira kwa orthopedic.

Amayi samalimbikitsidwa kugwiritsa ntchito tampons ya ukazi pa mankhwala chifukwa chowopsa cha candidiasis.

Zotsatira za Ofloxin zitha kukulitsa chizolowezi cha myasthenia gravis, odwala omwe amakonda kupezeka ndi porphyria - zimathandizira pakuwonjezeka, ndi kupezeka kwa bacteriological ya chifuwa chachikulu - imapereka zotsatira zabodza.

Ngati matenda a impso kapena kwa chiwindi, kuwunika pafupipafupi kuchuluka kwa mankhwalawa mu plasma kumafunika. Chifukwa cha chiwopsezo chakumwa poizoni, odwala omwe ali ndi vuto laimpso komanso kwa chiwindi amafunika kusintha kwa mlingo.

Mowa pa nthawi ya mankhwala ndi Ofloxin amatsutsana.

Kugwiritsa ntchito njira yothetsera kulowetsedwa kwa ana kungatheke pokhapokha ngati kukuwopseza moyo wa mwana, pamene sizingatheke kugwiritsa ntchito mankhwala ena ocheperako, mutatha kuyeserera mosamala za zabwino zomwe zikuyembekezeka komanso zoopsa zomwe zingachitike chifukwa cha zovuta zake. Popereka mankhwala, pafupifupi tsiku lililonse mlingo umalimbikitsidwa mu 0,0075 g pa 1 kg ya kulemera kwa mwana, mlingo waukulu sayenera kupitirira 0,015 g pa 1 kg.

Kuyanjana kwa mankhwala osokoneza bongo

Ndi munthawi yomweyo kugwiritsa ntchito Ofloxin:

• Cimetidine, methotrexate, furosemide ndi mankhwala omwe amateteza katulutsidwe ka tubular - kamakulitsa kuchuluka kwa ofloxacin m'madzi a m'magazi,
• Mankhwala omwe amaletsa kutupa, omwe amachokera ku methylxanthines ndi nitroimidazole - amawonjezera chiopsezo cha zotsatira za neurotoxic,
• Glucocorticosteroids - amachulukitsa chiopsezo cha kupindika kwa tendon, makamaka odwala okalamba,
• Inhibitors a carbonic anhydrase, sodium bicarbonate, citrate (mankhwala omwe alkalinize mkodzo) - amawonjezera mwayi wokhala ndi zotsatira za nephrotoxic, crystalluria.

Akaphatikizidwa ndi ofloxacin, chiwonetsero cha theophylline chimatsika ndi 25%, ndipo mulingo wa glibenclamide m'madzi am'magazi umachulukana.

Amafuna kuwunika dongosolo la magazi pakuphatikizana ndi mankhwala osakanikirana ndi anticoagulants osadziwika - otsutsana ndi vitamini K.

Zogulitsa ndi maantacid okhala ndi calcium, aluminium, mchere wamchere kapena magnesium amachepetsa kuyamwa kwa ofloxacin, kotero nthawi yayitali pakati pa kayendetsedwe kake ndi utsogoleri wa Ofloxin iyenera kukhala maola 2 kapena kupitilira.

Chiwopsezo chowonjezera nthawi ya QT imachulukitsidwa ndikuphatikizidwa ndi mapiritsi a Ofloxin omwe ali ndi antiarrhythmic mankhwala a kalasi IA ndi III, macrolides, antidepressants a tricyclic (mankhwala omwe amalimbikitsa nthawi ya QT).

Yankho la Ofloxin limagwirizana ndi mankhwala 0,9% sodium chloride solution, 5% fructose solution, yankho la Ringer, 5% shuga (dextrose), koma silingasakanikirane ndi heparin.

Mafanizo a Ofloxin ndi awa: Zanocin, Zoflox, Ofloxacin, Ofloxacin Protekh, Oflotsid, Lofloks, Vero Ofloxacin, Glaufos, Dancil, Tarivid, Uniflox, Phloxal.

Ndemanga za Ofloxine

Malinga ndi ndemanga zambiri, Ofloxin ndi mankhwala amphamvu othana ndi matenda opatsirana omwe amayambitsidwa ndi tizilombo tating'onoting'ono tomwe timayamwira.

M'mawu ena osonyeza kuti pali mkhalidwe woipa, zotsatira zoyipa zimafotokozedwa, kuphatikizapo kuchepa kwa chilakolako cha chakudya, kupweteka kwambiri m'mimba, kugona, kufoka, kuwunika masana, komanso kukhazikika kwa masipodi.

Mtengo wa Ofloxin m'masitolo ogulitsa mankhwala

Mtengo woyenerera wa Ofloxin: yankho la kulowetsedwa 2 mg / ml - ma ruble 127-163. 1 pamabotolo a 100 ml okhala ndi mapiritsi a 200 ml - 172-180 ma ruble. pa paketi 10 pcs.

Maphunziro: Yoyamba University State Medical University yotchedwa I.M. Sechenov, wapadera "General Medicine".

Zambiri zokhudzana ndi mankhwalawa ndizofanana, zimaperekedwa pazidziwitso ndipo sizilowa m'malo mwa malangizo aboma. Kudzipatsa nokha mankhwala kuopsa!

Ku UK kuli lamulo malinga ndi momwe dokotala wothandizira amatha kukanirana opaleshoni ngati atasuta kapena wonenepa kwambiri. Munthu ayenera kusiya zizolowezi zoipa, kenako, mwina, sangafunikire opaleshoni.

Mankhwala ambiri poyamba anali ogulitsidwa ngati mankhwala osokoneza bongo. Mwachitsanzo, a heroin adagulitsidwa ngati mankhwala a chifuwa. Ndipo cocaine adalimbikitsidwa ndi madokotala ngati opaleshoni komanso ngati njira yowonjezerera kupirira.

Munthu amene amamwa mankhwala opondeleza nthawi zambiri amakhalanso ndi nkhawa. Ngati munthu athana ndi kukhumudwa paokha, ali ndi mwayi wonse wakuyiwalako zamtunduwu mpaka kalekale.

Ntchito yomwe munthu samakonda imakhala yovulaza psyche yake kuposa kusowa kwa ntchito konse.

Vibrator woyamba adapangidwa m'zaka za zana la 19. Adagwira ntchito pa injini yankhonya ndipo adapangira kuti azitsatira khungu la akazi.

Pali ma syndromes osangalatsa kwambiri azachipatala, monga kuphatikiza zinthu.M'mimba mwa wodwala m'modzi wodwala mania uyu, zinthu 2500 zakunja zidapezeka.

Ngati mungagwere kuchokera pabulu, mukuluka khosi lanu kusiyana ndi kugwa kuchokera pa kavalo. Ingoyesani kutsutsa mawu awa.

Anthu omwe amakonda kudya chakudya cham'mawa nthawi zambiri amakhala onenepa kwambiri.

Malinga ndi kafukufuku, azimayi omwe amamwa magalasi angapo a mowa kapena vinyo pamlungu amakhala pachiwopsezo chotenga khansa ya m'mawere.

Munthu aliyense samangokhala ndi zala zapadera, komanso chilankhulo.

Pochezera pafupipafupi pakama pofufuta, mwayi wokhala ndi khansa yapakhungu umawonjezeka ndi 60%.

Nthawi yayitali yotsala ndiyotsika ndi yoyipa.

Asayansi aku America adayesera mbewa ndipo adati madzi amadzi amalepheretsa kukula kwa atherosulinosis yamitsempha yamagazi. Gulu limodzi la mbewa limamwa madzi am'madzi, ndipo lachiwiri ndi madzi a mavwende. Zotsatira zake, zombo za gulu lachiwiri zinali zopanda ma cholesterol.

Zoposa $ 500 miliyoni pachaka zimagwiritsidwa ntchito pa mankhwala azisamba okha ku United States. Kodi mukukhulupilirabe kuti njira yoti mugonjetse ziwengo ikapezeka?

Okonda akapsopsona, aliyense wa iwo amataya 6.4 kcal pamphindi, koma nthawi yomweyo amasinthana mitundu pafupifupi 300 ya mabakiteriya osiyanasiyana.

Chiwerengero cha antchito aku ofesi chakwera kwambiri. Izi ndizodziwika kwambiri m'mizinda yayikulu. Ntchito yamaofesi imakopa amuna ndi akazi.

Kupanga ndi mawonekedwe a kumasulidwa

Pamsika wamankhwala, mankhwalawa amaperekedwa m'njira ziwiri: mapiritsi amkamwa pakamwa ndi yankho la kulowetsedwa. Mapiritsi ozungulira a biconvex azungu kapena oyera achikasu, amakongoletsedwa m'matumba a matumba 7., M'katoni yazitupa ziwiri zokhala ndi malangizo ogwiritsira ntchito. Njira yothetsera vutoli ndi madzi amtundu wachikasu wobiriwira ndi fungo lamankhwala, lomwe limayikidwa mu botolo lagalasi. The kupezeka kwa mitundu yosiyanasiyana ya kumasulidwa kwa mankhwalawa:

Fomu yotulutsa katundu

Mapiritsi okhala ndi mbali

ofloxacin 200 kapena 400 mg (piritsi limodzi)

• povidone
• lactose monohydrate,
• crospovidone
• magnesium wakuba,
• talcum ufa
• wowuma chimanga
• poloxamer.

Kulowetsedwa njira

ofloxacin 200 mg (mu 1 botolo)

• disodium dihydrate,
• madzi a jakisoni.

Kugwiritsa ntchitolo

Ofloxin amadziwika pamaso pa ambiri matenda opatsirana ndi kutupa. Zomwe zikugwiritsidwa ntchito ndi ma antibayotiki ndi awa:

• bronchitis
• chibayo
• meningitis
• kunyowa
• blepharitis
• vaginitis
• vasculitis
• dermatitis
• laryngitis
• conjunctivitis
• colpitis
• yade
• enterocolitis
• prostatitis
• salpingitis
• chinzonono
• dacryocystitis
• pyelonephritis.

Momwe mungagwiritsire ntchitololeine

Mapiritsi a Ofloxin amayenera kumwedwa pakumwa pakudya kapena pambuyo chakudya. Mlingo ndi nthawi yayitali ya mankhwala amathandizidwa ndi adokotala atapimidwa ndikupeza zotsatira za labotale. Malangizo omwe aliwonse othandizira:

• M'malo ochepera komanso odziletsa a zotupa zopatsirana, kugwiritsa ntchito Ofloxin kumawonetsedwa kwa 0,4 g kamodzi m'mawa. Kutalika kwa chithandizo sikupitilira masiku 10.
• Mitundu yayikulu kapena kunenepa kwambiri, mlingo umakulitsidwa mpaka 0,8 g.
• Zochizira zosavuta zovuta zam'mimba kwamkodzo thirakiti, 0 ga 3 ayenera kumwedwa kwa masiku atatu.

Mankhwala mu mawonekedwe a yankho la kulowetsedwa kutumikiridwa kudzera m`mitsempha. Chithandizo cha mankhwalawa chimayamba ndi jekeseni imodzi yokha ya 0,2 ga mankhwala kwa mphindi 40-60. Pambuyo pakuwongolera, wodwalayo amasamutsidwa ku cholandirira mapiritsi omwewo. Kwa odwala omwe ali ndi vuto laimpso kapena chiwindi, matenda a cirrhosis, kuchuluka kwa mankhwalawa sikuyenera kupitirira 0,4 g.

Bongo

Kuchuluka kwa mlingo umodzi wa tsiku ndi tsiku wa Ofloxin kumatha kuyambitsa zotsatirazi za bongo:

• chizungulire
• kusanza
• kuyerekezera
• kulephera kudziwa
• kugwa
• achina,
• bronchospasm
• chisokonezo,
• kugona

Ngati Ofloxin adamwa mapiritsi, mapangidwe a m'mimba ayenera kuchitidwa. Mankhwala ena amatengera mawonetseredwe azachipatala.

Migwirizano yogulitsa ndikusunga

Ofloxin yothetsera ndi mapiritsi amafalitsidwa kuchokera ku pharmacies ndi mankhwala. Mankhwalawa amayenera kusungidwa pa kutentha kwa +10 ° C mpaka +25 ° C m'malo owuma osavomerezeka ndi ana aang'ono. Alumali moyo wa mapiritsi ndi zaka 3, yankho limasindikizidwa - 1 chaka, phukusi lotseguka - masiku 30. Ndi zoletsedwa kugwiritsa ntchito mankhwalawo tsiku lotha lisanathe.

Kutulutsa Mafomu

• Mapiritsi: wozungulira mawonekedwe, wokutira ndi mthunzi woyera, Mlingo wa 200 mg ndi 400 mg.
• 0,2% yankho la mtsempha wama mtsempha: yankho lomveka bwino, limatha kukhala ndi chikasu chachikasu, likupezeka mu Mbale 100 ml.
• Mafuta - oyera, atha kukhala ndi tint yachikasu, amapezeka m'matumba a aluminium a 15 mg ndi 30 mg.

Chithandizo cha Ofloxacin

Mlingo wa Ofloxacin
Mlingo wa antibayotiki wa matenda osiyanasiyana ndi wosiyana, ndipo uyenera kufotokozedwa ndi dokotala.

Chifukwa chake, pochizira matenda a genitourinary, piritsi limodzi (200 mg) nthawi zambiri limayikidwa nthawi 1-2 pa tsiku kwa masiku 7-10.

Mu matenda apakhungu a gonococcal, mumapezeka mlingo umodzi wa mapiritsi 4 mpaka 6 (200 mg).

Zochizira matenda a prostatitis, mapiritsi 1.5 mpaka 2 (200 mg) ndi mankhwala 2 kawiri pa tsiku.

Kwa gastroenteritis, piritsi limodzi (200 mg) 2 pa tsiku kwa masiku 5. Monga prophylactic, mapiritsi awiri (200 mg) kamodzi patsiku.

Monga prophylaxis ya sepsis, imwani mapiritsi awiri (200 mg) katatu patsiku.

Pa matenda a impso, chithandizo chimayikidwa payekhapayekha, ndipo piritsi loyamba limakhala piritsi limodzi la 200 (200 mg), kenaka piritsi 1 patsiku kapena piritsi 1 m'masiku awiri.

Ndi kuphwanya kwambiri chiwindi, musatenge mapiritsi awiri a 200 mg tsiku lililonse.

Mu matenda opweteka kwambiri a ziwalo zamkati ndi matenda a impso, yankho la mankhwalawa limayikidwa mu mawonekedwe a dontho, 100 ml yankho la 1-2 kawiri pa tsiku.

Ndi matenda a gonococcal, mankhwalawa amaperekedwa mu mtsempha wa 200 mg kawiri pa tsiku.

Ofloxacin wa chlamydia

Zochizira chlamydia, njira yochizira ndi mankhwalawa monga jakisoni kapena mapiritsi, ndi mankhwala omwe amachitika mosiyanasiyana.

Mlingo wa mankhwalawa umaperekedwa palokha, nthawi zambiri piritsi limodzi (jekeseni) 1-2 kawiri pa tsiku.

Pa chithandizo, sikulimbikitsidwa kugwiritsa ntchito zinthu zomwe zimachepetsa acidity ya m'mimba.
Zambiri Za Chlamydia

Ofloxacin ndi ureaplasmosis

Mankhwalawa ndi a anti-sipekitiramu mankhwala, chifukwa, amalembera mankhwalawa ureaplasmosis. Nthawi yomweyo, Ofloxacin amadziwika kuti ndi mankhwala othandiza kwambiri pochiza matendawa.

Tengani mankhwalawa monga mapiritsi a 400 mg 2 pa tsiku kwa masiku 7-10.
Zambiri za ureaplasmosis

Kugwirizana kwa ofloxacin ndi mankhwala ena

• Tengani zokonzekera zomwe zimakhala ndi ma antacid, sulfate, calcium, iron, zinc ziyenera kukhala maola awiri mutatha kumwa Ofloxacin kuti amwe bwino.
• Ndi osavomerezeka kumwa mankhwala omwe ali ndi anti-kutupa pofuna kupewa kukondoweza kwa chapakati mantha dongosolo.
• Mu shuga mellitus, ndikofunikira kuwongolera kuchuluka kwa shuga.

Ndemanga za mankhwala

Raisa, wa zaka 68
"Ofloxacin adamulembera kuchipatala atachitidwa opaleshoni. Ndinkadwala chifukwa chotupa, pakumva kupweteka kwambiri. Patatha masiku awiri amtundu wa mankhwalawo, zizindikirizo zinazimiririka ndikuyamba kusintha."

Nikolay, wazaka 28
"Atazindikira kuti ureaplasmosis, ndimaganiza kuti sangathe. Ndinatenga ofloxacin, anali wathanzi sabata limodzi."

Natalia, wazaka 52
"Ndidatenga conjunctivitis, ndinayesa mafuta ambiri, osagwira, pamapeto pake ndinayenera kupita kwa dokotala. Ofloxacin adalangizidwa, adalandira chithandizo kwa masiku angapo, zonse zidachotsedwa kwathunthu."

Pafupifupi odwala onse pakuwunika amawona kuti mtengo wotsika wa mankhwalawo uphatikizidwa ndi chithandiziro chabwino.

Mlingo ndi makonzedwe

Mlingo wa mankhwalawa umatengera mtundu komanso kuuma kwa matendawa, komanso chidwi cha zochita za mankhwala, zomwe zikuchitika pakadwala, ntchito ya impso ndi chiwindi.

Mapiritsi
Ofloxin amatengedwa pakamwa, kutsukidwa ndi madzi, musanadye kapena chakudya. Mapiritsi ayenera kumwa kwathunthu. Kugwiritsa ntchito moyenera ndi maantacid ayenera kupewedwa.

Mlingo wovomerezeka wa Ofloxin tsiku lililonse ndi 200-600 mg, odwala omwe ali ndi matenda oopsa kapena odwala olemera kwambiri angawonjezere mpaka 800 mg (mlingo wa 400 mg ungatenge kumwa kamodzi patsiku, makamaka m'mawa, Mlingo wapamwamba ukhoza kugawidwa m'magulu awiri phwando).

Kutalika kwa maphunzirowa ndi masiku 7-10.

Ndi matenda osavuta a kwam'mimba kwamkodzo, Ofloxin amalembedwa kwa masiku 3-5 tsiku lililonse 200 mg, ndi chinzonono - kamodzi 400 mg.

Wodwalayo atakhazikika bwino, mankhwala othandizira omwe amayambitsidwa ndi ofloxacin amatha kupitilizidwa ndi Ofloxin mkati osasintha mlingo.

Kulowetsedwa njira
Ofloxin amaperekedwa kudzera m'mitsempha.

Mlingo woyambirira ndi 200 mg kamodzi, mlingo wa makonzedwe uli mkati mwa mphindi 30-60. Matenda a wodwalayo atatha, Ofloxin amayenera kusamutsidwira mkati osasintha mlingo.

Malangizo othandizira (kutengera malo omwe ali ndi matendawa):

• Thirakiti la urin: Nthawi 1-2 pa tsiku, 100 mg iliyonse,
• Ziwalo za ENT, kupuma, khungu, mafupa, minofu yofewa, malo olumikizirana mafupa, komanso matenda opindika: 2 kawiri pa tsiku, 200 mg iliyonse (ndikotheka kuwonjezera mlingo umodzi pakanthawi 2),
• Impso ndi kumaliseche: 2 kawiri pa tsiku, 100-200 mg.

Odwala omwe ali ndi kuchepa kwa chitetezo chokwanira kuti ateteze matenda, Ofloxin amathandizidwa ndi 200 mg ya Ofloxin mu 5% shuga njira. Kutalika kwa kulowetsedwa ndi mphindi 30. Mutha kugwiritsa ntchito njira zatsopano zokonzekera.

Mitundu yonse ya mankhwalawa
Ndi makulidwe a impso, mlingo uyenera kusintha (kutengera chilolezo cha creatinine):

• Kuchokera pa 50 mpaka 20 ml pamphindi: kawiri pa tsiku, 50% ya mlingo umodzi kapena nthawi imodzi patsiku, 100% ya mlingo umodzi,
• Osakwana 20 ml pa mphindi: gawo limodzi lokha ndi 200 mg, kenako tsiku lililonse, 100 mg patsiku.

Ndi peritoneal dialysis ndi hemodialysis, Ofloxin amatchulidwa maola 24 aliwonse pa 100 mg.

Odwala omwe ali ndi vuto la chiwindi sayenera kupitilira muyeso wa tsiku lililonse wa 400 mg.