Mafuta a Argosulfan: malangizo ogwiritsira ntchito

Mankhwalawa amapezeka mu mtundu wa kirimu 2%, womwe umayimira kuchuluka kwa oyera kapena oyera ndi oyera kuchokera ku imvi kuwala mpaka pinki.

Zomwe zimagwira mu Argosulfan ndi sulfathiazole siliva. 1 g ya kirimu muli 20 mg yogwira pophika.

Omwe amachokera ku mankhwalawa:

• Mowa wa Cetstearyl - 84.125 mg,
• Vaselizi yoyera - 75,9 mg,
• Mafuta a paraffin - 20 mg,
• Glycerol - 53.3 mg,
• Sodium lauryl sulfate - 10 mg,
• Potaziyamu dihydrogen phosphate - 1,178 mg,
• Methylhydroxybenzoate - 0,66 mg,
• Sodium hydrogen phosphate - 13,052 mg,
• Propylhydroxybenzoate - 0,33 mg,
• Madzi d / i - mpaka 1 g.

Kirimu ya Argosulfan imagulitsidwa mu machubu a zotayidwa a 15 kapena 40 g, atanyamula makatoni a 1 pc.

Zisonyezero zogwiritsira ntchito Argosulfan

Mankhwalawa amalembera kuwotcha kwama degree onse amtundu uliwonse (kuphatikiza dzuwa, matenthedwe, ma radiation, mantha amagetsi, mankhwala), mabala amadzimadzi otayika, kuvulala kwapakhomo kakang'ono (abrasions, mabala).

Kugwiritsa ntchito kwa Argosulfan kumathandizira zilonda zam'munsi zam'magazi osiyanasiyana, kuphatikizira endarteritis, erysipelas, kuperewera kwa venous, komanso angiopathies a shuga mellitus.

Kuphatikiza apo, zonona zimagwiritsidwa ntchito ngati frostbite, bedores, microbial eczema, impetigo, streptostaphyloderma, kulumikizana kosavuta komanso dermatitis.

Contraindication

Zoyipa zomwe zimagwiritsidwa ntchito ndi Argosulfan ndi:

• Kukula msanga ndi ubwana mpaka miyezi iwiri (chifukwa chakukula kwa "nyukiliya" ya nyukiliya),
• Congenital kusakwanira kwa enzyme shuga-6-phosphate dehydrogenase,
• Hypersensitivity ku sulfathiazole siliva ndi sulfonamide ena.

Mlingo ndi kasamalidwe ka Argosulfan

Kirimu ya Argosulfan imapangidwira ntchito zakunja. Itha kuyikidwa pakhungu lotseguka kapena kuvala kavalidwe ka occlusive (hermetic). Dera lomwe lakhudzidwa ndi khungu liyenera kutsukidwa kaye, kenako ndikutsukanso zonona.

Zilonda zonyowa (ndi mapangidwe a exudate) musanagwiritse ntchito Argosulfan, khungu limathandizidwa ndi 3% yamadzi yankho la boric acid kapena 0,1% yankho la chlorhexidine.

Kirimuyo amauyika kudera lomwe lakhudzidwalo ndi wosanjikiza wa 2-3 mm mpaka minofuyo itachira kwathunthu, komanso ngati pakalumikizidwa khungu, mpaka bala lakonzeka kukachitidwa opaleshoni. Pa chithandizo ndi Argosulfan, zonona ziyenera kuphimba kwathunthu khungu lowonongeka.

Kutalika kwa mankhwala ndi mlingo wa mankhwalawa zimatsimikiziridwa payekhapayekha.

Malangizo a Argosulfan akuti zonona ziyenera kugwiritsidwa ntchito kuyambira 1 mpaka 3 pa tsiku, pomwe mlingo woyenera wa tsiku lililonse sayenera kupitirira 25. Nthawi yayitali ya maphunzirowa ndi miyezi iwiri.

Zotsatira zoyipa za Argosulfan

Nthawi zina, thupi limagwirizana ndi khungu. Nthawi zina m'malo mogwiritsa ntchito zonona, kukwiya kumatha kuchitika, kuwonetsedwa ndi mphamvu yoyaka.

Pogwiritsa ntchito Argosulfan kwa nthawi yayitali, kusintha kwa magazi ndikotheka, komwe kumakhala kachitidwe ka zonse systemic sulfonamides (agranulocytosis, leukopenia, etc.), komanso desquamative dermatitis.

Malangizo apadera

Chisamaliro chimayenera kuthandizidwa mukamagwiritsa ntchito zonona mu ntchito yodwalitsa odwala omwe amawotcha kwambiri, popeza palibe njira yosonkhanitsira chidziwitso chonse.

Ndi chithandizo cha nthawi yayitali, magawo a madzi am'magazi amayenera kuyang'aniridwa, makamaka magawo a sulfatiazole. Izi makamaka zimakhudza odwala omwe ali ndi matenda a impso ndi chiwindi.

Malangizo opita ku Argosulfan akuti samakhudza kuyendetsa magalimoto ndipo angagwiritsidwe ntchito mwa odwala omwe zochitika zawo zimayenderana ndi chidwi chowonjezeka.

Analogs of Argosulfan

Palibe zoyerekeza zonse za Argosulfan potengera mchere wamchere wa sulfathiazole. Ma mafuta ena, mafuta amkati kapena mafuta onunkhira a sulfanilamide omwe ali ndi vuto lofananalo amayimiridwa ndi mankhwalawa:

• Arghedin (wopanga Bosnalijek, Bosnia ndi Herzegovina), Dermazin (Lek, Slovenia) ndi Sulfargin (Tallinn Pharmaceutical Plant, Estonia) ndi mafuta omwe chopangira chake ndi sulfadiazine wa siliva. Amapangidwa mu chubu cha 40, 50 g, komanso m'mtsuko wa 250 g. Amagwiritsidwa ntchito pazomwezi monga Argosulfan. Kuphatikiza apo, sulfanamide iyi imagwira ntchito motsutsana ndi bowa wamtundu wa Candida ndi dermatophytes, chifukwa chomwe imatha kuperekedwa kwa candidiasis ndi mycoses ena a pakhungu.

• Mafenide acetate mafuta 10% imapezeka mu phukusi la 50 g mumtsuko. Mankhwalawa amathandizanso kupewa ndi candida,

• Mafuta a Streptocide ndi liniment 5% ndi 10% amapezeka mumtsuko wa 25 ndi 50. Zizindikiro zamagwiritsidwe ntchito ndizofanana ndi Argosulfan.

Mankhwala

Argosulfan ndi imodzi mwamankhwala akunja okhala ndi antibacterial. Imapereka chitetezo chokwanira pamabala pathupi kuchokera kumatenda, imalimbikitsa machiritso a trophic, kuwotcha ndi mabala amatsukidwe, imachepetsa nthawi ya mankhwalawa komanso nthawi yakukonzekera chilonda kuti chiike khungu. Nthawi zambiri, kusintha kumawonedwa, kumachotsa kufunika kosinthira.

Gulu la Nosological (ICD-10)

Mankhwala

Argosulfan ® ndi mankhwala osokoneza bongo a antibacterial omwe amalimbikitsa machiritso a zilonda (kuphatikizapo kuwotcha, trophic, purulent), amateteza chitetezo mabala ku matenda, amachepetsa nthawi yothandizira komanso nthawi yakukonzekera bala kuti ubalike pakhungu, nthawi zambiri kumabweretsa kusintha, kuthetsa kufunika kosinthira.

Sulfanilamide, sulfathiazole wa siliva, yemwe ali gawo la zonunkhirazi, amagwiritsa ntchito mankhwala othana ndi bacteria ndipo ali ndi mawonekedwe ambiri a antibacterial bacteriostatic zochita motsutsana ndi gramu-gramu ndi gram-negative bacteria. Kapangidwe ka antimicrobial zotsatira za sulfathiazole - zoletsa kukula ndi kubereka kwa tizilombo ting'onoting'ono - timagwirizana ndi kupikisana kwa PABA ndi kuletsa kwa dihydropteroate synthetase, komwe kumayambitsa kusokonezeka kwa kaphatikizidwe ka dihydrofolic acid ndipo, makamaka, metabolite yake, tetrahydrofolic acid, yofunikira ya synthesis ya pulypimides.

Ma ayoni a siliva omwe akukonzekera kukonzekera amakulitsa mphamvu ya antibacterial ya sulufanilamide - amalepheretsa kukula ndi magawikidwe a mabacteria pomangiriza ku ma cell a micros DNA. Kuphatikiza apo, ma ayoni a siliva amafooketsa chidwi cha katundu wa sulfonamide. Chifukwa chochepetsetsa cha mankhwalawa, alibe poizoni.

Pharmacokinetics

Sulfathiazole ya siliva yomwe ili pokonzekera imakhala ndi mphamvu yaying'ono, chifukwa, pambuyo pake, ntchito yogwiritsidwa ntchito pachilondacho imasungidwa nthawi yomweyo. Ndi sulfathiazole ochepa chabe omwe amawoneka m'magazi, pambuyo pake amatsika m'chiwindi. Mumkodzo mumakhala mawonekedwe a metabolites osagwira komanso osasinthika pang'ono. The mayamwidwe siliva sulfathiazole kumawonjezera pambuyo ntchito pa kwambiri bala mabala.

Zisonyezero za mankhwala Argosulfan ®

kutentha kwa magawo osiyanasiyana, mwachilengedwe chilichonse (kuphatikiza matenthedwe, dzuwa, mankhwala, magetsi, ma radiation),

zilonda zam'mimbazi zam'munsi zamiyendo yosiyanasiyana (kuphatikizapo kuperewera kwa venous kuchepa, kufalikira kwa endarteritis, kusokonezeka kwa matenda a shuga mellitus, erysipelas),

kuvulala kwapakhomo kakang'ono (mabala, abrasions),

dermatitis, impetigo, zosavuta kukhudzana ndi khungu, michere

Mlingo ndi makonzedwe

Kwathu onse ndi njira yotseguka, komanso pansi pazovala zamatsenga.

Pambuyo poyeretsa komanso kuchitira opaleshoni, mankhwalawa amagwiritsidwa ntchito pachilondacho ndi wosanjikiza wa 2-3 mm potsatira chikhalidwe chosawilitsidwa katatu patsiku. Zilonda panthawi ya chithandizo ziyenera kuphimbidwa ndi zonona. Ngati gawo la chilondacho likutseguka, kirimu wowonjezera uyenera kuyikiridwa. Kavalidwe ka occlusive ndizotheka, koma osafunikira.

Kirimuyo amauyika mpaka chilondachoichira kwathunthu kapena mpaka khungu limalidwa.

Ngati mankhwalawa agwiritsidwa ntchito pamavuto omwe ali ndi kachilombo, exudate imatha kuoneka.

Musanagwiritse ntchito zonona, ndikofunikira kutsuka chilondacho ndi 0,1% yamadzi yankho la chlorhexidine kapena antiseptic wina.

Mulingo wambiri watsiku ndi tsiku ndi 25 g. Nthawi yayitali ya chithandizo ndi masiku 60.

Wopanga

Chomera cha mankhwala Elfa A.O. 58-500 Jelenia Gora, ul. B. Minda 21, Poland.

Wokhala ndi satifiketi yolembetsa: LLC "VALANTE". 115162, Russia, Moscow, ul. Shabolovka, 31, p. 5.

Zodandaula za makasitomala ziyenera kutumizidwa ku LLC "VALANTE". 115162, Russia, Moscow, ul. Shabolovka, 31, p. 5.

Tel./fax: (495) 510-28-79.

Zotsatira za pharmacological

Mafuta Argosulfan ali ndi antimicrobial, omwe amathandizira kuchira kwachangu kwa mabala a ma etiology osiyanasiyana (zotupa za purulent, trophic ulcerative changes, amayaka) Mankhwalawa amachepetsa ululu, amaletsa matenda a mabala, amachepetsa nthawi yochira. Nthawi zina, motsutsana ndi momwe ntchito mankhwalawo imagwiritsidwira ntchito, kufunika kwakekupandukira zikopa.

Kirimu ya Argosulfan imakhala ndi imodzi mwa sulfonamides - sulfathiazole, yomwe yatchulidwa kuti imayambitsa matenda, imagwira tizilombo tating'onoting'ono. Maonekedwe a zochita za wogwira ntchitoyo ndi ma gramu okhala ndi gram komanso maluwa opanda gramu. Njira yayikulu yogwiritsira ntchito antibacterial cholinga chake ndikulepheretsa kubereka komanso kukula kwa tizilombo tating'onoting'ono poletsa ntchito ya dihydroperoate synthetase komanso mpikisano wokonda kupikisana ndi PABA. Zotsatira zake, momwe amapangira dihydrofolic acid ndi metabolite yake yayikulu, tetrahydrofolic acid, yomwe ndiyofunikira pakapangidwe, amasintha pyrimidines ndi purines tizilombo.

Zikomo ma ayoni a siliva The antimicrobial mphamvu ya sulfonamide imatheka chifukwa chomangirira ku bacteria bakiteriya ndikutsatira kwachulukidwe kamene kamakula komanso kugawa kwa tizilombo tosiyanasiyana. Kuphatikiza apo, ma ayoni a siliva amalepheretsa chidwi cha sulfonamide.

PH yoyenera kwambiri ndi hydrophilic base ya kirimu imathandizira kuti hydrate ikhale pachilonda, imathandizira kuchiritsa, opaleshoni.

Malangizo ogwiritsira ntchito (Njira ndi Mlingo)

Mankhwalawa sanapangidwire pakamwa, amangogwiritsa ntchito zakunja kokha. Kirimuyi imatha kupaka mabala otseguka, kugwiritsa ntchito chovala chapadera cha occlusive ndikololedwa. Mankhwalawa amagwiritsidwa ntchito pakhungu loyeretsedwa, kutsatira malamulo a asepisi, antiseptics. Pamaso pa exudate, chisanachitike kuchitira khungu ndi yankho kumalimbikitsidwa. boric acid 3%, kapena yankhochlorhexidine0,1%.

Malangizo a Argosulfan:mankhwalawa amathandizidwa ndi makulidwe owonda a 2-3 mm mpaka chilondacho chitsekeka kwathunthu kapena mpaka chovundikirana ndi khungu. Tsiku lililonse amalimbikitsa 2-3 Tsiku lililonse mutha kuyikirapo kuposa 25 g mafuta. Kutalika kwa njira ya chithandizo ndi miyezi iwiri. Ndi nthawi yayitali, mosalekeza, kuyang'anira magwiridwe antchito a chiwindi ndi aimpso amafunika.

Mimba (ndi mkaka wa m'mawere)

Pa nthawi ya bere mimba Argosulfan angagwiritsidwe ntchito pokhapokha pakufunika mwachangu, mwachitsanzo, pakuwonongeka pakhungu ndi malo oposa 20%. Kuyamwitsa Ndikulimbikitsidwa kuleka chifukwa chakumwedwa pang'ono kwa mankhwalawo.

Ndemanga za Argosulfan

Muzochita zamankhwala, zonona zadzikhazikitsa ngati chida chabwino kwambiri pothandizira pakuwotcha kwa dera lalikulu. Mabwalo amawu ndi ma portals azachipatala omwe odwala wamba amagawana zomwe akumva zimakhala ndi ndemanga zabwino za Argosulfan. Amayi achichepere amasiya ndemanga zawo zamafuta, ndikuwonetsa kulekerera kwake bwino ndi ana aang'ono, kuthamanga kwambiri pochotsa abrasions, mabala ndi mabala.

Malangizo a Argosulfan: njira ndi mlingo

Kirimu ya Argosulfan imagwiritsidwa ntchito kunja, chithandizo chimayikidwa ndi njira yotseguka kapena chovala cha occlusive.

Kirimuyo umagwiritsidwa ntchito kumalo omwe akhudzidwa ndikugawidwa mu wosanjikiza ngakhale 2-3 mm. Kudzimbidwa kumachitika mu wosabala nthawi 2-3 patsiku mpaka bala limachiritsidwa kwathunthu kapena kupatsirana khungu. Pa mankhwala, zonona ziyenera kuphimba kwathunthu madera onse a zotupa, ngati gawo la chilondacho likutseguka, wosanjikiza ayenera kubwezeretsedwanso.

Ngati mafomu exudate pochiza mabala omwe ali ndi kachilombo ka Argosulfan, musanayikenso zonona, chilondacho chiyenera kutsukidwa ndikuchiritsidwa ndi antiseptic solution (madzi amchere a chlorhexidine 0,1%).

Mulingo wovomerezeka wa tsiku ndi tsiku wa kirimu ndi 25 g. Kutalika kwa chithandizo sikupitilira miyezi iwiri.

Kuyanjana kwa mankhwala osokoneza bongo

Kirimuyi siyikulimbikitsidwa kuti igwiritsidwe ntchito nthawi yomweyo ndi mankhwala ena akunja.

Kuphatikizika ndi folic acid ndi mawonekedwe ake osakanikirana kumachepetsa mphamvu ya antimicrobial ya mankhwala.

Mndandanda wa Argosulfan ndi: Sulfathiazole siliva, Sulfargin, Streptocide, Dermazin.