Cardiomagnyl: malangizo ogwiritsira ntchito

Mankhwala Cardiomagnyl ndi nthumwi ya gulu lazachipatala ndi zamankhwala othandizira antiplatelet. Amagwiritsidwa ntchito pofuna kupewa thrombosis mu ma pathologies osiyanasiyana a mtima.

Kutulutsa mawonekedwe ndi kapangidwe kake

Cardiomagnyl ikupezeka mu mawonekedwe a mapiritsi, mapiritsi okhala pakompyuta oyendetsera pakamwa. Mulinso zinthu ziwiri zomwe zimagwira - acetylsalicylic acid 75 kapena 150 mg ndi magnesium hydroxide 15.2 kapena 30,9 mg piritsi limodzi. Phalelo lilinso ndi zinthu zina zothandiza, monga:

Mbatata ndi wowuma chimanga.
Magnesium wakuba.
Hypromellose.
Cellcose wa Mycrystalline.
Talc.
Propylene glycol.

Mapiritsiwa ndi oyera mu utoto, mawonekedwe awo ndi osanjidwa ngati mtima. Zili mu botolo lagalasi lamdima. Paketi imodzi yamakatoni muli botolo lomwe lili ndi mapiritsi ndi malangizo ogwiritsira ntchito mankhwalawa.

Zotsatira za pharmacological

Acetylsalicylic acid, yomwe ndi gawo la mankhwalawa, ndi mankhwala osapweteka a antiidal. Imalepheretsa (inhibits) ma enzyme cycloo oxygenase (COX 1 ndi 2), yomwe imapangitsa kutembenuka kwa arachidonic acid kukhala ma prostaglandins. Prostaglandins, kuphatikiza pa kutsitsa-kutulutsa mphamvu, imatenganso gawo lina la kuphatikizana kwa maselo ambiri (gluing) pakapangidwe ka intravascular thrombus. Chifukwa chake, kuponderezedwa kwa COX kumabweretsa kutsika kwa ma prostaglandins komanso mwayi wa thrombosis. Mulingo wambiri wotsutsana ndi kusakanikirana umaonekera pamene mulingo wa acetylsalicylic acid ndi 75-150 mg, Mlingo wapamwamba umagwiritsidwa ntchito pa analgesic, anti-kutupa kwenikweni komanso kutentha kwapansi kwa thupi kwa mitundu yambiri yotupa.

Magnesium hydroxide imaphatikizidwa pakuphatikizidwa kwa mankhwalawa kuti muchepetse mavuto obwera chifukwa cha acetylsalicylic acid pamitsempha ya mucous yam'mimba.

Mutatenga piritsi ya Cardiomagnyl, asidi acetylsalicylic imafulumira ndipo imakhala yolowa mu kayendedwe kamatumbo kuchokera ku lumen. Imagawidwanso m'thupi lonse ndipo imapangidwa m'chiwindi. Zinthu zopanda pake zosinthana ndi acetylsalicylic acid zimaponyedwa mkodzo. Hafu ya moyo (kuchotsedwa kwa theka lathunthu) kumatenga pafupifupi maola 12. Magnesium hydroxide simalowetsedwa mu kayendedwe ka kayendedwe kazachilengedwe, mphamvu yake ya zamankhwala imadziwika mwachindunji m'matumbo am'mimba.

Cardiomagnyl ndi chiyani?

Mapiritsi a Cardiomagnyl amasonyezedwa pazinthu zosiyanasiyana zamatenda, limodzi ndi chiopsezo chowonjezeka cha intravascular thrombosis:

Kusakhazikika kwa angina pectoris ndikuphwanya kwakukulu kufalikira kwa magazi mu mtima ndi kuthekera kwakukulu kokulira kwa myocardial infarction (kufa kwa gawo la minofu yamtima).
Kupewera kwa intravascular thrombosis mu matenda a shuga, kulephera kwa mtima, kunenepa kwambiri, kusuta, matenda oopsa, komanso kuwonjezereka kwa magazi, komanso kukalamba.
Kupewa pafupipafupi myocardial infarction kapena intravascular thrombosis.

Mankhwalawa amagwiritsidwanso ntchito kuti ateteze thromboembolism (mapangidwe amitsempha yama cell m'mimba ndi kufalikira kwa imodzi mwa iwo) atachitidwa opaleshoni yamitsempha, makamaka corteryary artery bypass grafting (CABG), percutaneous coronary angioplasty.

Contraindication

Kugwiritsa ntchito mapiritsi a Cardiomagnyl amatsutsana m'matenda a pathological (makamaka pothana ndi vuto la kutulutsa magazi kapena kutaya kwamkati m'ziwalo zamkati), zimaphatikizapo:

Kutupa kwa magazi mkati mwa dongosolo lamkati lamanjenje, makamaka muubongo.
Kutulutsa magazi m'mimba.
A pathological amakonda kukhala ndi magazi ndikusowa kwa vitamini K m'thupi, hemorrhagic diathesis, thrombocytopenia.
Erosive-ulcerative pathology ya kapangidwe kake ka m'mimba, komwe amadziwika ndi chiopsezo chotaya magazi kuchokera ku vuto la mucosal, makamaka mu gawo la kufalikira kwamatenda.
Kuperewera kwa enzyme glucose-6-phosphate dehydrogenase, yomwe imakhudza magawo ndi magwiridwe antchito a maselo ofiira a magazi.
Zofanana makonzedwe a methotrexate.
Ana osakwana zaka 18.
Nthawi ya bere mu I ndi II trimester ya maphunziro ake, komanso yoyamwitsa.
Kulephera kwakukulu kwaimpso.
Mphumu ya bronchial, yomwe kukula kwake kumakhala kovutitsidwa ndi kugwiritsa ntchito mankhwala aliwonse a gulu la mankhwala, omwe si a antiidal.
Kusalolera payekha kwa acetylsalicylic acid, magnesium hydroxide kapena magawo othandizira a mankhwalawo.

Mochenjera, mankhwalawa amagwiritsidwa ntchito kwa hepatic kapena aimpso kulephera kufatsa, kufinya, kupezeka kwa kukokoloka kapena zilonda zam'mimba mu chikhululukiro (zamankhwala ndikusintha kwa ma laboratory), "aspirin triad" (mphumu ya bronchial, mphuno ya mphuno, kuponderezana kwa aspirin), pakati pa III trimester. Musanayambe kumwa mapiritsi a Cardiomagnyl, muyenera kuonetsetsa kuti palibe zotsutsana.

Mlingo ndi makonzedwe

Mapiritsi a Cardiomagnyl amatengedwa pakamwa ponse, samatafunidwa ndikusambitsidwa ndi madzi okwanira. Pa kupewa chachikulu kwa thrombosis ndi matenda amtima, Mlingo wa mankhwalawa ndi 75 mg 1 nthawi patsiku, pomwe piritsi limakonda kumwa mankhwalawa nthawi ya 19.00, njira ya mankhwalawa ndi yayitali. Ngati kuli koyenera kupewa kutulutsa mobwerezabwereza myocardial infarction, osakhazikika angina, mlingo umasiyanasiyana pakati pa 75-150 mg patsiku. Mlingo womwewo umagwiritsidwa ntchito pofuna kupewa thrombosis pambuyo pakuchita opaleshoni yamadzi. Dokotala amakhazikitsa nthawi ya chithandizo payekha.

Zotsatira zoyipa

Kumwa mapiritsi a Cardiomagnyl kumatha kubweretsa kukula kosakhudzidwa kuchokera ku ziwalo ndi machitidwe osiyanasiyana, monga:

Matumbo a pakhungu - kutentha kwa mtima nthawi zambiri kumayamba, kusanza, kusanza, kupweteka kwam'mimba ndi kutulutsa kwapamimba m'mimba, mapangidwe azilonda kapena kukokoloka kwa m'mimba thirakiti, komanso kukula kwa magazi m'mimba kumachitika kawirikawiri. Malo okhazikika okhala ndi mafuta ophikira (mapangidwe a dzenje) cham'mimba kapena zilonda zam'mimba, colitis (kutupa kwamatumbo akulu), matumbo osakwiya pamene mukumwa mankhwalawo akufotokozedwa.
Mitsempha yam'mimba - mutu, chizungulire, kusowa, kapena kusowa tulo, tinnitus, kawirikawiri sipakhala zotupa za intracranial.
Njira yopumira imakhala ya bronchospasm (kupendekera kwa lumen ya bronchi chifukwa cha kuwonjezeka kwakukulu kwa kamvekedwe ka minofu yosalala ya makoma awo).
Kufupika kwa mafupa ofiira ndi dongosolo la magazi - kuchuluka kwa magazi chifukwa chosakwanira kuphatikiza kupatsidwa zinthu za m'magazi, kuchepa magazi m'thupi. Osowa kwambiri, kuchepa kwamapulatifomu (thrombocytopenia) ndi neutrophils (neutropenia) amakula.
Thupi lawo siligwirizana - milandu ya chitukuko cha angioedema Quincke edema (plasma kutuluka kwa zinthu interferular ziwalo za nkhope ndi ziwalo zakunja), kawirikawiri anaphylactic mantha (kwambiri zokhudza zonse ziwengo ndi kuchepa kwa magazi ndi kukula kwa ziwalo zambiri) zimafotokozedwanso.

Kukula kwa zotsatira zoyipa mutatha kumwa mapiritsi a Cardiomagnyl ndiye maziko othandizira kusiya mankhwala.

Malangizo apadera

Musanayambe kumwa mapiritsi a Cardiomagnyl, muyenera kuwerenga mosamala malangizo a mankhwalawo, onetsetsani kuti palibe zotsutsana. Muyeneranso kuyang'anira malangizo apadera angapo, omwe ndi:

Kumwa mapiritsi a Cardiomagnyl kumatha kudzetsa mphumu ya bronchial, makamaka ngati zachitika mwa wodwalayo m'mbuyomu.
Pamaso pa opaleshoni yomwe ikukonzekera, mankhwalawo amatha kusiyidwa kwa masiku angapo, omwe amathandizidwa ndi kupewa kutaya magazi.
Kuphatikizika kwa kugwiritsa ntchito mankhwalawa ndi mankhwala ena a gulu lachipatala-mankhwala, ma antiplatelet othandizira ndi anticoagulants (kuletsa magazi) kumapangitsa kuti magazi azituluka kwambiri.
Acetylsalicylic acid imatha kupangitsa kuti gout ichitike mwa anthu ochepetsedwa uric acid mkodzo.
Kuphatikizidwa kwa mapiritsi a Cardiomagnyl omwe ali ndi methotrexate kumawonjezera chiopsezo cha zotsatirazi zamagazi ndi magazi.
Kugwiritsanso ntchito kwa glucocorticosteroids kumachepetsa asidi acetylsalicylic acid mthupi, chifukwa chake atathetsa, bongo la acetylsalicylic acid limatheka.
Mlingo waukulu wa mankhwalawa ungayambitse kukula kwa hypoglycemia (kuchepa kwa shuga wamagazi), komwe ndikofunikira kulingalira mwa anthu omwe ali ndi vuto la carbohydrate metabolism (shuga mellitus).
Sitikulimbikitsidwa kumwa mowa munthawi ya mankhwala ndi mankhwalawa, chifukwa izi zimawonjezera chiopsezo chakutuluka kwa m'mimba.
Kuphatikiza kwa kumwa mapiritsi a Cardiomagnyl okhala ndi ibuprofen sikumayikidwa kunja chifukwa cha chiwopsezo chowonjezeka cha zovuta zamtima zosiyanasiyana.
Mankhwalawa sakukhudza mwachindunji ntchito zamatumbo a cortex, koma pokhudzana ndi zovuta zomwe zingayambike, kusamala kuyenera kuchitidwa pogwira ntchito yomwe imafunikira chidwi chochulukirapo komanso kuthamanga kwa zochitika zama psychomotor.

Patsamba lapaupilisi, mapiritsi a Cardiomagnyl amaperekedwa popanda mankhwala a dokotala. Komabe, sikulimbikitsidwa kuti ayambe kugwiritsa ntchito popanda mankhwala oyenerera a dokotala.

Zisonyezo angiocardil

Mu zovuta mankhwala a matenda a mtima (angina pectoris, myocardial infarction), mtima kulephera, cardialgia motsutsana maziko a sitormonal mtima.

Mankhwala osokoneza bongo a ngozi ya cerebrovascular (ischemic stroke, cerebrovascular insufficiency).

Kuchepetsa magwiridwe antchito, malingaliro komanso thupi (kuphatikizapo pakati pa osewera).

Alcohol achire matenda (kuphatikiza ndi enieni mankhwala a uchidakwa).

Monga gawo la zovuta mankhwala a hemophthalmus ndi retinal hemorrhage osiyanasiyana etiologies, thrombosis ya chapakati retine mtsempha ndi nthambi zake, retinopathies a osiyanasiyana etiologies (matenda ashuga, matenda oopsa).

Kugwiritsa ntchito angiocardil pa mimba komanso mkaka wa m`mawere

Contraindified mu mimba. Pa nthawi ya chithandizo ayenera kusiya kuyamwitsa.

Angiocardyl ndi metabolic wothandizira.

Meldonium ndi analogue yojambula ya gamma-butyrobetaine - chinthu chomwe chimapezeka mu khungu lililonse la thupi la munthu.

Imalepheretsa gamma-butyrobetaine hydroxylase, imachepetsa kaphatikizidwe ka carnitine ndi kayendetsedwe kazakudya zamafuta tambiri kudzera m'mitsempha yama cell, ndikulepheretsa kudzikundikira kwa mitundu yamafuta a acid, zotumphukira za acylcarnitine ndi acylcoenzyme A m'maselo. Pankhani ya kuwonongeka kwa pachimake kwa ischemic ku myocardium, kumachepetsa mapangidwe a necrotic zone ndikufupikitsa nthawi yokonzanso. Kulephera kwamtima kosalekeza (CHF), kulolerako kumakulitsa. Ndi angina pectoris, kuchuluka kwa kukomoka kumachepa. Mu pachimake komanso matenda a ischemic matenda amitsempha yamagazi amatulutsa magazi mozungulira ischemia, amathandizira kugawa magazi mokomera dera la ischemic. Kugwiritsa ntchito ngati mtima ndi dystrophic fundus matenda.

Imalimbikitsa kugwira ntchito kwamthupi, kumachepetsa kuopsa kwa zizindikiro za kupsinjika kwa m'maganizo ndi thupi. Imayendetsa chitetezo cham'manja komanso chochititsa manyazi. Amachotsa mawonekedwe owonetsa mu zakumwa zoledzeretsa ndi kusiya.

Bioavailability ndi mtsempha wa magazi makonzedwe ndi 100%. Kuzindikira kwakukulu (C _max ) m'magazi am'madzi amapezeka atangokhazikitsidwa.

Metabolism: zimapukusidwa mu thupi ndi kupangika kwa ma metabolites awiri akuluakulu omwe amatsitsidwa ndi impso.

Kuchotsa: theka-moyo (TU.) ndi maola 3-6.

Zotsatira zoyipa za angiocardyl

Kuchokera pamtima: kawirikawiri - tachycardia, kuchepa kapena kuwonjezeka kwa kuthamanga kwa magazi.

Kuchokera ku dongosolo lamanjenje lalikulu: kawirikawiri - psychomotor mukubwadamuka, kusowa tulo.

Kuchokera m'mimba: kawirikawiri - mavuto a dyspeptic

Zotsatira zoyipa: kawirikawiri - kuyabwa, kuzimiririka, kuzimiririka pakhungu, angioedema.

Zizindikiro zasayansi: eosinophilia.

Zina: kawirikawiri - kufooka kwathunthu.

Meldonium si mankhwala a mzere woyamba wa matenda oopsa a coruseary ndipo kugwiritsa ntchito sikofunikira mwachangu.

Pochiza odwala omwe ali ndi matenda a chiwindi ndi impso, muyenera kusamala, makamaka pogwiritsa ntchito mankhwalawa.

Zizindikiro: kuchepa kwa kuthamanga kwa magazi, limodzi ndi mutu, tachycardia, chizungulire komanso kufooka wamba.

Imawonjezera zotsatira za kuchepa kwa magazi ndi mankhwala ena a antihypertgency, mtima glycosides.

Chifukwa cha kukula kwa tachycardia wolimbitsa thupi komanso ochepa hypotension, kusamala kuyenera kuchitidwa pophatikizidwa ndi nitroglycerin, nifedipine, alpha-blockers, antihypertensive mankhwala, komanso zotumphukira vasodilators.

Itha kuphatikizidwa ndi antianginal mankhwala, anticoagulants, antiplatelet agents, antiarrhythmic mankhwala, okodzetsa, bronchodilators.

Pamalo amdima pa kutentha kwa 15 mpaka 25 ° C. Moyo wa alumali ndi zaka 2.

Pharmacodynamics ndi pharmacokinetics

Wikipedia imanena kuti acetylsalicylic acid Ndi salicylic ester ya acetic (ethanoic) acid ndipo imatha kuchepetsa ululu, kuchepetsa kutentha ndi kutupa, komanso kupewa zoletsa kuchuluka kwa mapulateleti.

Acetylsalicylic acid (ASA) imalepheretsa enzyme COX-1, kuchititsa kutsekeka kwa mkhalapakati wofunikira kuchuluka kwa mapulateleti TXA-2 ndi zoletsa zosakanikirana kuchuluka kwa mapulateleti.

Amakhulupirira kuti ASA imalepheretsa kuphatikizika kuchuluka kwa mapulateleti ndipo munjira zina, kotero angagwiritsidwe ntchito ndi mitundu yokwanira bwino matenda a mtima.

Ma magnesium hydroxide omwe amapezeka m'mapiritsi amateteza mucosa wam'mimba chimbudzi kuchokera ku ASA.

ASA imatengedwa kuchokera m'matumbo am'mimba pafupifupi voliyumu yonse. T1 / 2 ya thunthu - pafupifupi mphindi 15. Kuchulukitsa kumeneku kumachitika chifukwa chakuti m'magazi am'magazi, chiwindi ndi matumbo acetylsalicylic acid mwachangu hydrolyzed kuti salicylic (SC).

Chifukwa salicylic acid T1 / 2 - pafupifupi maola atatu. Njira zama enzyme zikadzaza, zomwe zimadziwika ndi nthawi yomweyo ya ASA muyezo woposa 3 g, chizindikirocho chimatha kukula kwambiri.

The bioavailability wa ASA pafupifupi 70%. Chizindikirocho chimadziwika ndi kusinthasintha chifukwa chakuti chinthucho chimayang'aniridwa ndi hydrolysis yoyambira motsogozedwa ndi michere. The bioavailability ya SC ndichokera 80 mpaka 100%.

Mlingo wa magnesium hydroxide yomwe imagwiritsidwa ntchito sizikuwakhudza bioavailability wa ASA.

Pharmacokinetics

ASA imatengedwa kuchokera m'matumbo am'mimba pafupifupi kwathunthu. Hafu ya moyo wa ASA ili pafupifupi mphindi 15, chifukwa ndi kutenga nawo ma enzymes, ASA imatulutsidwa mofulumira kuti salicylic acid (SC) m'matumbo, chiwindi, ndi madzi a m'magazi. Hafu ya moyo wa SC ili pafupifupi maola atatu, koma imatha kuwonjezeka komanso kuyang'anira munthawi yomweyo milingo yayikulu ya ASA (kuposa 3.0 g) chifukwa cha kuchuluka kwa njira zama enzyme.

The bioavailability ya ASA ndi pafupifupi 70%, koma kufunika kwake kumasiyana, popeza ASA imayang'aniridwa hydrolysis (mucous membrane wa m'mimba thirakiti, chiwindi) mu SC pansi pa michere. The bioavailability wa SC ndi 80-100%.

Mlingo wa magnesium hydroxide yomwe imagwiritsidwa ntchito sizikhudza bioavailability wa acetylsalicylic acid.

Gwiritsani ntchito pa nthawi yoyembekezera komanso nthawi yoyamwitsa

Kugwiritsa ntchito milingo yayikulu ya salicylates m'miyezi itatu yoyambirira ya kubereka kumalumikizidwa ndi kuchuluka kwa zolakwika za fetal. Mu trimester yachiwiri yokhudzana ndi kubereka, ma salicylates amatha kuyikidwa pokhapokha ngati akuwonetsetsa kuti ali pachiwopsezo komanso kupindula.

Mu trimester yomaliza yamimba, ma salicylates omwe ali ndi mlingo waukulu (wopitilira 300 mg / tsiku) amalepheretsa kugwira ntchito, kutsekeka msanga kwa ductus arteriosus mu mwana wosabadwayo, kuchuluka kwa magazi m'mayi ndi mwana wosabadwayo, komanso kuyang'anira asanabadwe kungayambitse kukha magazi kwakanthawi, makamaka ana akhanda.

Kukhazikitsidwa kwa salicylates mu trimester yomaliza yam'mimba imatsutsana.

Zambiri zomwe zimapezeka kuchipatala ndizosakwanira kukhazikitsa njira yomwe ingagwiritsidwe ntchito poyamwitsa. Musanapereke mankhwala acetylsalicylic acid mukamayamwitsa, phindu lomwe lingakhalepo lamankhwala liyenera kuyesedwa poyerekeza ndi chiopsezo cha makanda.

Bongo

Pogwiritsa ntchito mankhwala ochepetsa mphamvu ya mapiritsi a Cardiomagnyl, tinnitus imayamba, nseru, kusanza, chizungulire komanso chisokonezo zimatha. Chithandizo cha mankhwala osokoneza bongo otere amakhala ndi kutsuka m'mimba, matumbo, kugwiritsa ntchito matumbo am'mimba (activated kaboni) ndi chizindikiro. Kuchulukitsa kwakukulu kwa mlingo (overdose) kumatha kubweretsa kuwonjezeka kwa kutentha kwa thupi (kutentha thupi), kupuma kwamphamvu (hyperventilation ya mapapu), komwe kumayambitsa kukula kwa zamchere (zamchere zamagazi) ndi kuphwanya kwamphamvu kwa ntchito ya chapakati yamanjenje ndi mtima. Pankhaniyi, kuchipatala kwadzidzidzi kumachitika ndi kuchipatala komanso kulandira chithandizo kuchipatala.

Aspecard, Aspirin Cardio, Acecor Cardio, Reocard, Polokard ndi ofanana pankhani ya chinthu chogwira ntchito komanso zovuta zamankhwala komanso zothandizira odwala mapiritsi a Cardiomagnyl.

Kutulutsa mawonekedwe, zikuchokera

Angiocardyl amapezeka mwanjira yothetsera jakisoni wopanda mtundu. Amathiridwa mu ma ampoules okhala ndi mphamvu ya mamililita asanu. Mu paketi amodzi amakhadi pamakhala 5 kapena 10 mwa ampoules otere.

Mililita imodzi ya yankho imakhala ndi mamiligalamu 100 a meldonium dihydrate kusungunuka m'madzi a jakisoni.

Kuchita ndi mankhwala ena

Mukagwiritsidwa ntchito limodzi ndi kutsitsa kwa magazi ndi mankhwala ena kuti muchepetse kuthamanga kwa magazi, komanso glycosides yamtima, Angiocardyl amatha kulimbikitsa mphamvu yawo.

Ndi munthawi yomweyo makonzedwe a angiocardil ndi nifedipine, nitroglycerin, zotumphukira vasodilators, mankhwala kuchepetsa magazi ndi alpha-adrenergic blockers, ochepa hypotension ndi pang'ono tachycardia.

Mankhwala omwe tatchulawa atha kumwa popanda kuopa kufanana ndi bronchodilators, antianginal mankhwala, antiplatelet othandizira, anticoagulants, diuretics ndi antiarrhythmic mankhwala.

Migwirizano ndi magwiritsidwe akusungidwa

Angiocardyl iyenera kusungidwa kuti isafikire ana ndi kutetezedwa mosavomerezeka ndi dzuwa, kutentha kwa madigiri 15 mpaka 25 Celsius.

Moyo wa alumali wa mankhwalawa ndi zaka ziwiri. Pambuyo pa nthawi imeneyi, simungathe kugwiritsa ntchito Angiocardil.

M'masitolo ogulitsa mankhwala omwe amapezeka ku Russian Federation, mtengo wapakati wa mankhwala omwe ali pamwambawa ndi ma ruble 220.

M'malo ogulitsa mankhwala opezeka ku UkraineAngiocardyl osati zogulitsa pano.

Mankhwala otsatirawa amatha kutchedwa analogues a angiocardil:

Odwala ambiri amayankha bwino angiocardil. Ngati mukufuna malingaliro a anthu enieni okhudzana ndi mankhwalawa, mutha kuwapeza kumapeto kwa nkhaniyi.

Pomaliza

Angiocardyl ndi mankhwala omwe amagwiritsidwa ntchito popanga zovuta za matenda a mtima ndi matenda ena.

Mankhwalawa amatha kugwiritsidwa ntchito mu ophthalmology ndi mankhwala amasewera.

Angiocardyl amapangidwa ngati jakisoni.

Itha kutengedwa kudzera m'mitsempha, intramuscularly ndi parabulbarno.

Chofunikira chachikulu pa mankhwalawa ndi meldonium.

Kugwiritsa ntchito angiocardyl nthawi zina kumatha kuyambitsa zovuta zina, komanso thupi lanu.

Pali ma contraindication otenga angiocardil.

Ana, komanso amayi oyembekezera komanso oyamwitsa, saloledwa kugwiritsa ntchito mankhwalawa.

Pali mankhwala omwe amatha kutchedwa analogues a angiocardyl.

Gwiritsani ntchito mankhwalawa pokhapokha mukaonana ndi dokotala.

Angiocardil, malangizo ntchito: njira ndi mlingo

Angiocardyl imayendetsedwa kudzera m'mitsempha (i / v), intramuscularly (i / m) kapena parabulbar. Popeza mankhwalawa amatha kuwonetsa zosangalatsa, ndikulimbikitsidwa kuti mugwiritse ntchito m'mawa.

Njira yoyendetsera yankho, mlingo ndi nthawi ya chithandizo zimayikidwa payekhapayekha, poganizira zomwe zikuwonetsa, kuopsa kwa vutolo ndi zinthu zina.

Mlingo woyenera wa angiocardyl (monga gawo la mankhwala osakanikirana):

myocardial infaration: 500-1000 mg (5-10 ml ya yankho) iv m'mitsempha, 1 nthawi patsiku kapena agawidwa 2 jakisoni, kenako ndikusinthira kukamwa kwa meldonium
khola angina pectoris, CHF yotsatsa cardioomyopathy Cardialgia: 500-1000 mg (5- ml ml) i.v. mumtsinje, 1 nthawi patsiku kapena wogawika m'magawo awiri, kapena 500 mg i / m 1-2 pa tsiku, Maphunzirowa ndi masiku 10 mpaka 14, pomwe kusintha kwa njira zamkamwa kumapangidwira, njira yonse ndi masiku 28 mpaka 42,
ngozi ya cerebrovascular (pachimake ndi kuperewera kwa mphamvu ya cerebrovascular): 500 mg (5 ml) iv kapena kuwonjezera pazosakwanira - i / m, 1 nthawi patsiku kwa masiku 10, ndikutsatira makonzedwe apakamwa, ambiri - 28-27 masiku, malinga ndi lingaliro la adokotala omwe ali ndi mawonekedwe osakhazikika, ndizotheka kuchititsa maphunziro obwereza kawiri katatu pachaka,
syndrome yoletsa mowa: 500 mg (5 ml) IV kapena IM kawiri pa tsiku, kumene - masiku 7-10,
retinal hemorrhages ndi hemophthalmus osiyanasiyana etiologies, retinopathy, thrombosis of the central retinal mtsempha ndi nthambi zake: 50 mg (0.5 ml) parabulbarno, kumene - masiku 10,
kupsinjika kwakukulu pamthupi ndi m'maganizo: 500 mg iv kapena IM kamodzi patsiku, kumene - masiku 10 mpaka 14, ngati pangafunike, patatha masiku 14-21, kosi yachiwiri ndiyotheka.

Cardiomagnyl kapena Thrombital, ndibwino bwanji?

Mankhwala ndi fanizo lathunthu ndipo amagwiritsidwa ntchito pazofanana. Kupangidwa ndi opanga osiyanasiyana. Cardiomagnyl ndi mankhwala achi Japan, kampaniyo ili ndi zomera ku Denmark, Germany, Russia, Trombital ndi mankhwala akunyumba.

mankhwala oyamba
ma CD osiyanasiyana
lalitali pamsika waku Russia,
kutchuka kambiri
mapiritsi a mitundu yosiyanasiyana, omwe amakulolani kuti musadzisakanize,
mumapezeka mankhwala onse
mtengo - kuchokera ku ma ruble a 130.

ma CD osiyanasiyana
maonekedwe a ma paketi osiyanasiyana mitundu yosiyanasiyana,
mtengo - kuchokera ku ma ruble 120.

pafupifupi mawonekedwe ofanana amipiritsi yosiyanasiyana,
atayamba kupanga ku Russia, anthu ena adazisiya.

tsiku lotha ntchito ndilochepa
kusakhulupirika kwa odwala chifukwa cha dzina latsopanoli,
osagawa zowopsa,
osati mumafakisi onse,
mapiritsi onse amawoneka ofanana.

Cardiomagnyl kapena Thrombo Ass, ndibwino bwanji?

Mankhwalawa ali m'gulu lomweli la pharmacotherapeutic - othandizira antiplatelet. Kuphatikizikako kumaphatikizapo acetylsalicylic acid (ASA), magnesium hydroxide imawonjezeredwa ku Cardiomagnyl. Ali ndi mawonekedwe ofanana, amagwiritsidwa ntchito ngati kupewa kwa myocardial infarction, sitiroko, kupatula kwa magazi pambuyo pa kuchitira opaleshoni.

ma CD osiyanasiyana
magnesium imateteza khoma la m'mimba ku zotsatira za ASA,
mapiritsi osiyanasiyana amakulolani kuti musasokoneze mlingo,
Mapiritsi amatha kugawidwa kapena kuphwanyidwa,
mtengo - kuchokera ku ma ruble a 130.

ma CD osiyanasiyana
phale lakhala lophimba ndi nembanemba yapadera yoteteza m'mimba,
Ubwino waku Europe
mtengo - kuchokera ku ma ruble 50.

Mapiritsi ogawanika sangasungidwe, makutidwe ndi okosijeni amapezeka ndipo zinthu zochizira zimatayika,
zovuta zina.

Mapiritsi saloledwa kuti agawidwe chifukwa cha chipolopolo.
simungathe kutenga pamimba yopanda kanthu,
contraindations zambiri.

Cardiomagnyl kapena Aspirin Cardio, ndibwino bwanji?

Mankhwalawa amagwiritsidwa ntchito kuthandizira magazi, ngati ngozi yachitika m'matumbo, poteteza matenda a mtima, ndi zina. Cardiomagnyl ndi othandizira antiplatelet, ndipo Aspirin Cardio ndi NSAID.

osiyanasiyana ma CD ndi mankhwala,
anawonjezera magnesium kuti pakhale kulolerana kwa mankhwalawa m'mimba,
kuloledwa kugawana mapiritsi,
mapiritsi a mitundu yosiyanasiyana ali ndi mawonekedwe a geometric osiyanasiyana, omwe amawathandiza kuti asasokonezeke,
mtengo - kuchokera ku ma ruble a 130.

kupezeka mosiyanasiyana
Mapiritsiwa ndi ophatikizidwa am'matumbo omwe amateteza m'mimba,
mankhwala oyamba
kuwerenga kowonjezera
mtengo - kuchokera 135 ma ruble.

zovuta zina
moyo wamfupi walifupi.

samakhala nthawi zonse m'mafakisi - mavuto ampikisano,
silingathe kugawidwa chifukwa chipolopolo
mapaketi a mitundu yosiyanasiyana amawoneka ofanana - mutha kusakaniza mukamagula,
contraindations zambiri.

Kuyanjana kwa mankhwala osokoneza bongo

zotumphukira vasodilators, antihypertensives, alpha-blockers, nifedipine, nitroglycerin: kuwoneka kwa tachycardia wosatsika ndi kuchepa kwa kuthamanga kwa magazi kungadziwike, ndi kuphatikiza kwa mankhwalawa, chisamaliro chiyenera kutengedwa,
mtima glycosides, mankhwala ochepetsa mphamvu ya m'magazi, mankhwala ena a antihypertgency: njira zochizira zoterezi zimathandizidwa,
antianginal and antiarrhythmic mankhwala, antiplatelet othandizira, anticoagulants, bronchodilators, diuretics: kugwiritsa ntchito mankhwalawa ndi meldonium ndikuloledwa.

Ma Analogs a Angiocardyl ndi Meldonium Organika, Idrinol, Meldonium, Vasomag, Meldonium-SOLOpharm, Meldonat-Lekpharm, Meldonium-Eskom, Ripronat VM, Meldonium-Binergia, Meldonium-DECO ndi ena.

Ndemanga za Angiocardil

Ndemanga zochepa za angiocardyl ndizabwino kwambiri. Odwala amadziwa mphamvu ya mankhwalawa akamagwiritsa ntchito pakukonzanso kwa postoperative. Zotsatira zabwino zimapezeka chifukwa chogwiritsa ntchito njira zovuta za matenda a mtima, kuchepa kwa mtima ndi ngozi za mtima komanso komanso pakakhala kupsinjika kwa thupi ndi kwamaganizidwe. Monga tatsimikiziridwa, Angiocardyl amawongolera momwe zimakhalira, amathandizira kuthetsa kupuma pang'ono komanso amachepetsa pafupipafupi kupweteka kwamtima, kumawonjezera mphamvu, kumathandizira kupirira, kumalimbikitsa kusintha kwa thupi.

Zotsatira zoyipa, malinga ndi ndemanga, ndizosowa kwambiri.

Mapiritsi a Cardiomagnyl - amachokera kuti?

Zisonyezero Cardiomagnyl:

lakuthwa (myocardial infaration (IM) angina wosakhazikika) kapena matenda a ischemic a mtima,
kupewa kwakukulu kwa matenda a CVD mwa odwala omwe ali pachiwopsezo (akuvutika ndi kunenepa kwambiri, matenda ashuga, ochepa matenda oopsa, hypercholesterolemia, komanso kukhala ndi mbiri yabanja yosonyeza myocardial infarationosakwana zaka 55)
kupewa kwakukulu pachimake venous thrombosis komanso kupewa maphunziro okonzanso kuundana kwa magazi (kupewa kwachiwiri kwa thrombosis).

Malangizo Cardiomagnyl

Otsutsa otsatirawa a mankhwalawa adalembedwa monotation:

Hypersensitivity kwa ASA, masicicates ena,
tsankho pa chilichonse cham'mapiritsi othandizira,
zakwiya zilonda zam'mimba,
kutulutsa magazi (hemophilia,thrombocytopeniakulephera vitamini K),
kukanika kwambiri (ndi GFR pansipa 10 ml pa mphindi) kapena kulephera kwa impso,
kuvunda kwamtima,
choyambitsidwa ndi kugwiritsa ntchito ma NSAIDs / salicylates Edema wa Quincke kapena mphumu ya bronchial mu anamnesis,
zaka za ana
trimester yomaliza ya mimba
phwando munthawi yomweyo methotrexate Mlingo wopitirira 15 mg / sabata.

Malangizo ogwiritsira ntchito Cardiomagnyl

Ndi matenda a mtima (munjira iliyonse), mlingo woyambira ndi 150 mg / tsiku. Ndi chithandizo chokonzanso, theka la mankhwala limayikidwa.

Ndi kusakhazikika angina pectoris/ MI ya pachimake, mulingo woyenera kwambiri umachokera pa 150 mpaka 450 mg / tsiku.

Momwe mungatenge Cardiomagnyl kupewa?

Poletsa maphunziro obwereza kuundana kwa magazi pa magawo oyambirira a mankhwalawa, wodwalayo adalandira 150, mtsogolo - 75 mg / tsiku.

Mlingo wa Prophylactic kuti mupewe CVD (i.e. pachimake coronary syndrome) ndi thrombosis - 75 mg / tsiku.

Kodi ndingamwe mankhwalawa mpaka liti?

Kutalika kwa makonzedwe kumatengera mawonekedwe a matendawa ndi kuopsa kwa matendawa.

Nthawi zina (malinga ndi zomwe zikuwonetsa, kutsata zolakwika ndikumayang'aniridwa pafupipafupi ndi kuthamanga kwa magazi ndi kuwundana kwa magazi), mankhwalawa amatha kuikidwa moyo wonse.

Kuchuluka kwa nthawi yokwanira kumwa mankhwalawa kungadziwike ndi adokotala.

Chingalowe m'malo ndi Cardiomagnyl?

Analogs Cardiomagnyl malinga ndi code ya ATC, kapangidwe kazinthu zogwira ntchito ndi mawonekedwe omasulidwa: Acard, Asacil-A, Aspeter, Aspirin Cardio, Acetylsalicylic acid, Magnikor, Thrombo ACC, Supombolic Cardio, Thrombogard, Ecorin.

Mitu ya mankhwala omwe ali ndi pafupi ndi momwe angachitire: Avix, Agrenox, Aspigrel, Brilinta, Vazotik, Monofram, Deplatt, Sylt, Ipaton, Clopidogrel, Chipinda, Lopigrol, Miogrel, Plavigrel, Plavix, Ma Trombeks, Zotsatira.

Mtengo wa ma Cardiomagnyl analogues amachokera ku ma ruble 8.

Zomwe zili bwino: Cardiomagnyl kapena Thromboass?

Mapiritsi a Thrombo ACC ndi NSAID omwe amagwiritsidwa ntchito kupewa sitiroko, vuto la mtima, mitsempha yakuya, thromboembolism ndi zina zambiri matenda. Maziko a mankhwalawo ndi acetylsalicylic acid.

Mfundo za zochita za Cardiomagnyl ndi analogi yake zimatengera luso la ASA kuti tiletse kapangidwe ka thromboxane ndi Pg, komwe kumathandizira kuchepetsa kuphatikizira komanso kudziphatika kuchuluka kwa mapulateletikomanso kuchepetsa kutupa.

Kuphatikiza apo, onse mankhwalawa amachepetsa zomwe zimadalira K-kudalira zinthu komanso kukulitsa ntchito ya plasma.

Kusiyana kwakukulu kwa Cardiomagnyl kuchokera mmalo mwake: kapangidwe ndi mawonekedwe a kumasulidwa. Mapiritsi a Thrombo ACC ali ndi 50 kapena 100 mg ya ASA, ndipo magnesium hydroxide palibe. Kuti muchepetse mavuto obwera chifukwa cha ASA, mapiritsiwa amakhala ndi zokutetezani zapadera zoteteza khungu.

Odwala amasiya ndemanga yofanana ya mankhwalawa, koma Thrombo ACC, m'malingaliro awo opangidwira, samayambitsa zovuta zina.

Acecardol ndi Cardiomagnyl - kusiyana

Acecardol Ndi mankhwala omwe zosakaniza zake zimaphatikizanso ASA.Kusiyana kwake kuchokera ku Cardiomagnyl ndikusowa kwa magnesium hydroxide pakupanga, mawonekedwe omasulidwa (mapiritsi mu chipolopolo) ndi muyeso wa ASA (50/100/300 mg / tabu.).

MapiritsiAcecardolNdikulimbikitsidwa kutenga 1 r. / Tsiku. Cardiomagnyl mapiritsi amatengedwa pambuyo chakudya musanadye.

Zomwe zili bwino: Cardiomagnyl kapena Aspirin Cardio?

Aspirin Cardio Kukonzekera koyambirira kwa kampani Bayer AG. Chida chimenecho ndi cha gulu lokonzekera ASA lomwe lili ndi umboni waukulu kwambiri. Chifukwa cha membrane wapadera wa-enteric-soluble, mphamvu yake yogwira ntchito imatulutsidwa osati m'mimba, koma m'matumbo, chifukwa chake Aspirin Cardio imalekeredwa bwino ndi odwala kuposa masiku onse acetylsalicylic acid.

Mapiritsiwo akupezeka m'matayala apakalendala, omwe amalola kuti chiwongolero chithandizire pochiritsa odwala.

Cardiomagnyl nthawi yapakati

Mu trimester yoyamba, kudya kwakachulukidwe kwa salicylates kumalumikizidwa ndi kuchuluka kwa zolakwika pakukula kwa mwana wosabadwayo.

Mu 2nd trimester, mankhwala a gululi amagwiritsidwa ntchito poganizira njira zochizira thupi la mayi komanso ngozi zomwe zingakhalepo kwa mwana wosabadwa.

M'miyezi itatu yapitayi ya mimba, ma salicylates amatsutsana. Mu 3 trimester, kuchuluka kwa ASA kungayambitse kulepheretsa ntchito, kuwonjezera magazi (onse amayi ndi mwana wosabadwayo), komanso kutsekedwa msanga kwa botallal duct mwana wosabadwayo.

Kugwiritsidwa ntchito kwa ASA musanabadwe kungayambitse hemorrhagic cerebrovascular ngozi (makamaka ana akhanda asanakwane).

Ma salicylates ndi ma metabolic awo amapita mkaka wa m'mawere. Mwangozi makonzedwe ochepa a ASA pa mkaka wa m`mawere sikutanthauza kuti kuyamwitsa ndipo si limodzi ndi kukula kwa zosafunika mu mwana. Komabe, Mlingo wapamwamba kapena kugwiritsa ntchito mankhwalawa kwa nthawi yayitali amafunika kuthetsa chiwindi B.

Ndemanga pa nthawi yomwe mayi ali ndi pakati zimatiloleza kunena kuti nthawi zambiri mankhwalawa amatchulidwa kuti apewe zovuta zomwe zimachitika m'magulu omwe ali pachiwopsezo, pochiza matenda osakwanira komansogestosiskomanso chithandizo polyhydramnios.

Pafupifupi azimayi oyembekezera onse adazindikira kuti Cardiomagnyl imalekereredwa bwino, koma kusintha (makamaka, kuyang'ana kochepa komanso kuchuluka kwa magazi) kumaonekera patatha masiku 10 mpaka 14 atalandira chithandizo.

Ndemanga pa Cardiomagnyl

Ndemanga za Cardiomagnylum pamaforamu ndizosiyana. Odwala ambiri omwe amamwa mapiritsiwa monga adanenera ndi dokotala amakhutira nawo, koma nthawi zina malingaliro oyipa amapezekanso. Zomwe zimapangitsa kuti mtengo wotsika ukhale wotsika mtengo ndi mitengo yake komanso zotsatirapo zake.

Zotsatira za kafukufuku ndi kuwunika kwa akatswiri zikuonetsa kuti ASA ndiye mankhwala abwino mankhwala antithrombotic mwa odwala omwe ali pachiwopsezo mtima (kuphatikizapo zomwe zimachitika pa nthawi yoyembekezera).

Chofunikira cha Cardiomagnyl ndi kukhalapo kwa Mg hydroxide mu kapangidwe kake - "cholumikizira" chomwe chimalepheretsa kuchitika kwakuwonongeka kwa ASA ndipo, makamaka, erythematic-hemorrhagic mawonekedwe a NSAID gastropathy.

Kafukufuku wasonyeza kuti Cardiomagnyl ndiwothandiza kwambiri kuposa mitundu ya enteric ndi kuphatikizira kusakanikirana. kuchuluka kwa mapulateleti. Poterepa, pafupipafupi momwe zimayambira m'mimba yamagetsi ndizochepa kwambiri poyerekeza ndi zomwe zinkachitika Asipirin ndi Asipirinlomwe limapezeka mu mawonekedwe a mapiritsi a enteric.

Chifukwa chake, kukhala ndi zisonyezo zofananira ndi zotsutsana zomwe tikugwiritsa ntchito monga ASA, Cardiomagnyl ndiyotetezeka kwambiri, koma sikuthandiza, popewa zovuta za matenda a CCC.

Mtengo wa Cardiomagnyl: kuchuluka kwa 75 mg / 15.2 mg ndi 150 mg / 30.39 mg?

Mtengo wapakati wa mapiritsi a Cardiomagnyl 75 mg No. 100 mu pharmacies aku Ukraine ndi 85 UAH. Mutha kugula mapiritsi a Forte a 95-98 UAH (onyamula No. 100). Nthawi yomweyo, mtengo wa mankhwalawa ku Zaporozhye, Kiev, Kharkov kapena Odessa umasiyana pang'ono.

Mtengo wa Cardiomagnyl ku Moscow ndi St. Petersburg amachokera ku ruble 120. kwa ma CD No. 30 ndi kuchokera 215 ma ruble. kulongedza No. 100. Mtengo wamapiritsi a Forte amachokera ku 125 phukusi la No. 30 ndi 260 rubles. ndi kuchokera kunyamula No. 100.

Mtengo wa Cardiomagnyl

Mtengo wapakati wa mapiritsi a Cardiomagnyl ku pharmacies ku Moscow zimatengera kuchuluka kwawo phukusili, komanso kuchuluka kwa acetylsalicylic acid: