Kapangidwe ndi mawonekedwe a insulin "Apidra Solostar", mtengo wake ndi ndemanga za anthu odwala matenda ashuga, analogues

Mukaba jakisoni wa Apidra, monga mtundu wina uliwonse wa insulin, muyenera kutsatira zakudya.

Anthu ambiri odwala matenda ashuga omwe amaba jakisoni amaoneka kuti sangathe kupewa matenda a hypoglycemia. M'malo mwake, imatha kusunga shuga wokhazikika ngakhale ndi matenda oopsa a autoimmune. Ndipo makamaka, ndi matenda a shuga a 2 ochepa. Palibe chifukwa chakuwonjezera kuchuluka kwa shuga m'magazi anu kuti mudzilimbitse nokha motsutsana ndi hypoglycemia yoopsa. Onerani kanema pomwe Dr. Bernstein akufotokoza nkhaniyi ndi bambo wa mwana yemwe ali ndi matenda a shuga 1. Phunzirani momwe mungasinthire zakudya zopatsa thanzi komanso mulingo wa insulin.

Onani pansipa kuti mumve zambiri.

Apidra ndi mankhwala ochita chiyani?

Anthu ambiri amakhulupirira kuti Apidra ndi insulin yochepa. M'malo mwake, ndi mankhwala a ultrashort. Siyenera kusokonezedwa ndi insulin ya insrapid, yomwe ndiyifupi. Pambuyo pa utsogoleri, Apidra wowerengeka-pang'ono amayamba kuchita mwachangu kuposa kukonzekera kwakanthawi. Komanso, zochita zake zimatha posachedwa.

Makamaka, mitundu yochepa ya insulini imayamba kuchita mphindi 20-30 pambuyo pa jekeseni, ndi ultrashort Apidra, Humalog ndi NovoRapid - pambuyo pa mphindi 10-15. Amachepetsa nthawi yomwe wodwala matenda ashuga ayenera kudikira asanadye. Zambiri zikuwonetsa. Wodwala aliyense amakhala ndi nthawi yake yoyambira payekha komanso mphamvu ya zochita za jakisoni wa insulin. Kuphatikiza pa mankhwalawa omwe amagwiritsidwa ntchito, amadalira tsamba la jakisoni, kuchuluka kwa mafuta m'thupi ndi zinthu zina.

Chonde dziwani kuti odwala omwe ali ndi shuga omwe amatsata zakudya zama carb otsika, jakisoni wa insulin yochepa musanadye bwino kuposa mankhwala a ultrashort. Chowonadi ndichakuti zakudya zama carb zotsika mtengo zomwe zimakhala zopindulitsa kwa odwala matenda ashuga zimatengedwa pang'onopang'ono ndi thupi. Apidra amatha kuyamba kutsika shuga kale kwambiri kuposa puloteni yomwe idadyedwa ndikupukusidwa ndipo gawo lina limasandulika kukhala glucose. Chifukwa cha kusiyana pakati pa kuchuluka kwa zochita za insulin ndi chakudya, shuga m'magazi angatsike kwambiri, kenako ndikukula. Ganizirani kusintha kuchokera ku insulin Apidra kukhala mankhwala osakhalitsa, monga Actrapid NM.

Kodi nthawi ya jakisoni wa mankhwalawa ndi yotani?

Jekeseni aliyense wa insulin Apidra ndiwothandiza kwa maola pafupifupi anayi. Chiphuphu chotsalira chimakhala mpaka maola 5-6, koma sizofunikira. Kuchuluka kwa zochitika pambuyo pamaora 1-3. Muziwonetsanso shuga pasanadutse maola 4 kuchokera insulin. Kupanda kutero, mlingo wolandidwa wa mahomoni ulibe nthawi yokwanira kuchitapo kanthu. Yesetsani kuti musalole milingo iwiri ya insulin yolimba kuti izizungulira nthawi yomweyo. Kuti izi zitheke, jakisoni wa Apidra uyenera kuchitidwa mosiyanasiyana kwa maola osachepera anayi.

Apidra kapena NovoRapid: zili bwino?

Mitundu yonse iwiriyi ya insulin ya ultrashort ili ndi mafani ambiri. Amakhala ofanana wina ndi mzake, komabe, m'thupi lililonse la matenda ashuga, thupi limakumana nawo momwe limafunira. Yoyamba ndi iti? Sankhani nokha. Monga lamulo, odwala amapaka jakisoni yemwe amapatsidwa kwaulere.Ngati mankhwala akukwanira bwino, khalani pamenepo. Sinthani mtundu umodzi wa insulini pokhapokha ngati pakufunika kutero.

Tikubwerezanso kuti kwa odwala omwe ali ndi matenda amtundu wa 1 ndi mtundu wa 2 omwe amatsata zakudya zamafuta ochepa, ndibwino kugwiritsa ntchito insulin yayifupi, m'malo mwa Apidra, Humalog kapena NovoRapid. Ganizirani kusintha kwa mankhwala omwe amangokhala ngati mwachidule, monga Actrapid NM. Mwina izi zipangitsa kuti shuga wanu wamagazi akhale pafupi ndi masiku onse, amachotsere kudumpha kwawo.

Ndemanga 6 pa Apidra

Ndili ndi zaka 56, kutalika kwa 170 masentimita, kulemera kwa 100 kg. Ndakhala ndikuvutika ndi matenda ashuga a 2 pafupifupi pafupifupi zaka 15. Ndimabaya mitundu iwiri ya insulin - Insuman Bazal ndi Apidra. Ndimakhalanso ndimankhwala a matenda oopsa. Mlingo wa insulin: Insuman Bazal - m'mawa ndi madzulo ku 10 PIECES, Apidra m'mawa pa 8 PIECES, pa nkhomaliro komanso madzulo ku 10 PIECES. Pazifukwa zina, madzulo asanagone, shuga amadzuka 8-9, ngakhale mmawa wotsatira ndizachilendo pamtunda wa 4-6. Kusintha kwa mlingo wa insulin? Mukulitsa Apidra musanadye chakudya kapena Insuman Bazal m'mawa? M'mbuyomu, ndimangodya mapiritsi a Amaryl okha, koma shuga adayamba kukwera mpaka 15, ndiyenera kupanga insulin. Tithokoze yankho.

Kusintha kwa mlingo wa insulin?

Muyenera kuphunzira mosamala zolemba zowerengera zamlingo wautali komanso wachangu wa insulin womwe umayikidwa patsamba lino. Malingaliro kwa iwo aperekedwa pamwambapa.

Insuman Bazal amatanthauza mankhwala apakatikati omwe amalowa bwino ndi Levemir, Lantus kapena Tresiba.

Zaka 56 zakubadwa, kutalika kwa 170 masentimita, kulemera kwa 100 kg. Ndakhala ndikuvutika ndi matenda ashuga a 2 pafupifupi pafupifupi zaka 15. Ndimakhalanso ndimankhwala a matenda oopsa.

Ndikuganiza kuti mumachepetsa mwayi wanu wakufa kapena kukhala wolumala chifukwa cha zovuta zina zikubwera. Chiwopsezochi ndi chachikulu kwambiri. Dzichite iwe molimbika.

Moni Ndili ndi zaka 67, kutalika 163 cm, 60 cm. Type 2 matenda ashuga, owonda kwambiri, kwanthawi yayitali. Ndimalipira mothandizidwa ndi jakisoni wa insulin mu Mlingo wokhazikika - mayunitsi 22 a Lantus, katatu pa tsiku kwa mayunitsi 6. Mu sabata yatha, shuga adakwera kufika ku 18-20, ndipo m'mbuyomu nthawi zambiri anali mpaka 10. Ngakhale mlingo wa insulin kapena zakudya sizinasinthe. Pambuyo pa jekeseni wa Apidra, kuchuluka kwa glucose kumatha kuchepa kapena kukwera. Ubale uliwonse pakati pa chakudya, insulin ndi shuga wambiri wasowa. Kodi chifukwa chake chingakhale chiyani? Ndimaganizira za buledi. Sindili wokonzeka kusinthira ku chakudya cha Dr. Bernstein, chifukwa zovuta za impso zayamba kale. Ndikukhulupirira kuti mudzapeza yankho lanu ndi upangiri wina.

Mu sabata yatha, shuga adakwera mpaka 18-20

Matenda a chikumbumtima angayambike - matenda ashuga ketoacidosis kapena hypoglycemic coma

Izi ndizokwera pafupifupi kawiri kuposa anthu athanzi, komanso osati kasupe

Pambuyo pa jekeseni wa Apidra, kuchuluka kwa glucose kumatha kuchepa kapena kukwera. Kodi chifukwa chake chingakhale chiyani?

Zifukwa zomwe jakisoni wa insulin samachepetsa shuga, onaninso apa - Ht.

Sindili wokonzeka kusinthira ku chakudya cha Dr. Bernstein, chifukwa zovuta za impso zayamba kale.

Pali cholowa chake cha kuchuluka kwa impso 40-45 ml / min. Ngati chizindikiro chanu chotsika, ndiye kuti kwachedwa kwambiri kusinthira ku chakudya, sitimayi yachoka. Ndipo ngati ikadali yapamwamba, ndiye kuti mutha kupita. Ndipo mwachangu, ngati mukufuna kukhala ndi moyo. Onani http://endocrin-patient.com/diabetes-nefropatiya/ kuti mumve zambiri.

Moni Ndili ndi matenda ashuga amtundu wa 1 kuyambira pa February 2018, Kolya Lantus 2 kawiri pa tsiku komanso apidra wa chakudya. Masiku angapo omalizira, shuga akhala akugwiritsika zoposa 10. Ndipo akutsika kwambiri, makamaka Mlingo waukulu wa insulin. Poyamba ndinkaona kuti anali atali, koma tsopano palibe. Lero zinali zoopsa. Kudumpha mulingo wa glucose kuyambira 2 mpaka 16. Chochita?

Kutulutsa Fomu

Njira yothetsera vutoli ndi madzi opanda mandala. Apidra ndi njira yowonjezera yolandirira insulin yaumunthu, koma imagwira ntchito mwachangu osati motalika motengera mphamvu yonse. Mankhwalawa amaperekedwa m'gulu la radar ngati insulin yochepa.

Njira yothetsera vutoli imapezeka m'makalateni a ma syringe apadera. Mu katoni imodzi 3 ml ya mankhwalawa, sangathe kusintha. Sungani insulin mufiriji popanda kuzizira. Pamaso jakisoni woyamba, tulutsani cholembera mu maola angapo kuti mankhwalawo akhale otentha kwambiri.

Pharmacodynamics ndi pharmacokinetics

Mphamvu yayikulu ya mankhwalawa ndikuwongolera kagayidwe kachakudya ka glucose.Insulin amachepetsa kuchuluka kwa shuga, kukulitsa mayamwidwe a glucose ndi zotumphukira zimakhala - minofu ndi mafuta.

Insulin imathandizanso kupanga shuga m'magazi, imachepetsa mapuloteni, lipolysis, ndikuwonjezera kupanga mapuloteni.

Kafukufuku wamankhwala odwala omwe ali ndi matenda ashuga awonetsa kuti jakisoni wa subcutaneous amagwira ntchito mwachangu, koma zotsatira zake ndizochepa mu nthawi yonse poyerekeza ndi insulin yaumunthu yosungunuka.

Jakisoni amapangidwa mphindi ziwiri asanadye - izi zimathandizira kuyendetsa molondola kwa glycemic. Ikaperekedwa mukatha kudya pambuyo pa mphindi 15, imathandiza kuwongolera shuga. Mankhwalawa amasungidwa m'magazi kwa mphindi 98. Nthawi 4 - 6 maola.

Glulisin amachotseredwa mwachangu kuposa insulin yaumunthu. Kutha kwa theka-moyo kumapangitsa maminiti a 42.

Zizindikiro ndi contraindication

Malinga ndi kalozera wa mankhwalawa, amangopatsidwa matenda a shuga okha, omwe amafunikira kukhazikitsa mankhwala a insulin. Chinsinsi chofunikira kwambiri ndi ana osakwana zaka 6.

Mankhwalawa amatchulidwa pokhapokha ngati wodwalayo azindikiridwa ndi wodwala. Kufunika kogwiritsira ntchito insulin, mlingo wake umatsimikiziridwa ndi dokotala malinga ndi zotsatira za mayeso ndi zizindikiro za matenda. Kugwiritsa ntchito mosalamulirika kumayambitsa zovuta zosasintha.

Mtheradi wotsutsana wa mankhwalawa ndi hypoglycemia ndi ziwengo pazomwe zimapangidwira.

Pa mkaka ndi pakati, Apidra angagwiritsidwe ntchito. Kafukufuku wachipatala atsimikizira chitetezo cha mankhwalawa, makamaka mukamatsatira malamulo onse okhazikitsidwa ndi endocrinologist.

Zotsatira zoyipa

Zotsatira zoyipa kwambiri zimakhala ndi hypoglycemia. Nthawi zambiri amagwirizanitsidwa ndi mankhwala osokoneza bongo ambiri. Kuukira kwa kuchepetsa kwambiri shuga kumayendera limodzi ndi kunjenjemera, kuchuluka kwambiri ndi kufooka. Tachycardia yamphamvu ikusonyeza kuopsa kwa vutoli.

Patsamba la jakisoni, zimachitika zimatha - kutupa, zotupa, redness. Onsewa amadutsa okha patatha masabata awiri ogwiritsira ntchito. Matenda akulu kwambiri amakula kwambiri ndipo amakhala chizindikiro choti pakufunika kusintha kwakanthawi mankhwala.

Kufotokozera kwa mankhwalawa kukuwonetsa kuti kuphwanya njira ya jakisoni ndi mawonekedwe a minofu yodutsitsa nthawi zambiri kumayambitsa lipodystrophy.

Mlingo ndi bongo

Mankhwalawa amayenera kuperekedwa kwa mphindi 15 musanadye kapena pambuyo pake. "Apidra" imagwiritsidwa ntchito m'njira zosiyanasiyana za insulin - pogwiritsa ntchito insulin kapena mankhwala osokoneza bongo a nthawi yayitali. Apidra imapangidwanso pamodzi ndi mankhwala apakamwa omwe amachepetsa shuga m'magazi. Mlingo amasankhidwa ndi endocrinologist.

Lowani "Apidra" mwanjira ina kapena mwa kulowetsedwa kosalekeza m'mafuta a subcutaneous omwe ali ndi dongosolo la pampu.

Jakisoni amachitidwa m'mimba, mapewa, m'chiuno. Kupitiliza kosalekeza kumachitika m'mimba yokha. Ndikofunikira nthawi zonse kusintha malo a jakisoni ndi kulowetsedwa, amasinthana ndi kuyambitsa kulikonse. Kuchuluka kwa mayamwidwe, kuyamba kwake ndi nthawi yake zimakhudzidwa ndi:

• tsamba la jakisoni
• zolimbitsa thupi
• thupi
• nthawi yoyang'anira, ndi zina zambiri.

Pakulowetsedwa m'mimba, kunyowa kumathamanga.

Pofuna kuti mankhwala asalowe mumtsempha wamagazi, muyenera kutsatira njira zomwe madokotala amafotokoza, pophunzitsa odwala matenda a shuga. Pambuyo pa jekeseni, ndizoletsedwa kutikita minofu pamalopo.

Apidra ndi yovomerezeka kusakaniza kokha ndi insulin isophane. Mukamagwiritsa ntchito pampu, kusakaniza nkoletsedwa.

Ndi kudya kwambiri insulin mthupi, ngozi ya chiwopsezo cha hypoglycemia imakulanso. Mitundu yofatsa imayimitsidwa msanga potenga shuga kapena shuga, chidutswa cha shuga. Pankhaniyi, odwala matenda ashuga ayenera kukhala ndi shuga kapena china chilichonse chokoma ndi mafuta osavuta, msuzi wokoma, ndi zina zambiri.

Fomu yolimba, yowonetsedwa ndi kupsinjika, vuto la mitsempha, chikomokere imatha kuyimitsidwa ndikuyendetsa glucagon intramuscularly kapena subcutaneally, komanso njira yokhazikika ya dextrose. Zingwe ziyenera kuchitika ndi katswiri. Munthu akakhala kuti ali ndi chikumbumtima, muyenera kudya kena kokhala ndi mafuta osavuta kuti musadzachitenso zomwezo, zomwe zitha kuyambiranso pambuyo poti mumva bwino. Komanso, wodwalayo amakhala kuchipatala kwakanthawi, kuti dokotala azitha kuyang'anira wodwala wake pafupipafupi.

Kuchita

Pa maphunziro a pharmacological mogwirizana ndi insulin "Apidra" sanachitidwe. Kutengera chidziwitso cha mphamvu za analogues, kukulitsa zotsatira zamatenda okhudzana kwambiri ndi pharmacokinetic ndizotheka pang'ono. Zinthu zina zomwe zimapangidwa ndi mankhwala zimatha kuthana ndi kagayidwe ka glucose, motero, nthawi zina kusintha kwa insulin kumafunika.

Otsatirawa amalimbikitsa hypoglycemic zotsatira za Apidra:

• Hypoglycemic mankhwala opaka pakamwa,
• mafupa
• disopyramids
• fluoxetine
• pentoxifylline
• Asipirin
• sulfonamide antimicrobial mankhwala.

Kuchepetsa vuto la hypoglycemic:

• danazol
• kukula kwamafuta,
• proteinase zoletsa
• estrogens
• mahomoni a chithokomiro,
• amphanomachul.

Mowa, mchere wa lithiamu, beta-blockers, clonidine amathanso kufooketsa mphamvu ya mankhwalawa, ndikupangitsa kuukira kwa hypoglycemia ndi hyperglycemia yotsatira.

Zolemba ndi zofananira za mankhwala zimaperekedwa pagome.

Mankhwala "Apidra Solostar" ndimawaba kwa mphindi zochepa asanadye. Chochitacho ndichothamanga kwambiri, ndichabwino kwa ine. Komanso yabwino kugwiritsidwa ntchito mu phula la syringe. Pogwiritsa ntchito zovuta sizinawonekere ngakhale kamodzi.

Osati kale kwambiri pomwe ndidasinthidwa kukhala mankhwala a Apidra. Imagwira bwino komanso mwachangu, glucose ndiyachilendo. Ndimagwiritsa ntchito insulin musanadye, sindinazindikire kusapeza bwino pamalowo. Ndakhala ndikugwiritsa ntchito insulin iyi kwa miyezi 6, ndikhutira ndi mankhwalawa.

Alexandra, wazaka 65

Phukusi limodzi lokhala ndi syringes yapadera ya Apidra limawononga pafupifupi ma ruble 2100. Alumali moyo wa mankhwala osatseka ndi zaka 2 mufiriji. Kuchepetsa mwayi wokhala ndi lipodystrophy, mankhwalawa amawotha kutentha kwa chipinda asanagwiritse ntchito. Mutha kusunga mankhwala otseguka kwa milungu inayi pamalo pomwe dzuwa silimatenthetsa ndi kutentha kosaposa 25 digiri.

Pomaliza

Endocrinologists ali ndi lingaliro loti matenda a shuga siangopeka, koma njira ya moyo. Zimaphatikizapo kugwiritsidwa ntchito kovomerezeka kwa mankhwala, kutsatira malamulo azakudya. Kutsatira mosamalitsa pazabwino zonse ndikusankha mlingo woyenera ndiye chinsinsi cha moyo wapamwamba, ngakhale mutazindikira. Apidra amathandiza anthu ambiri odwala matenda ashuga kumva bwino komanso kuiwala za shuga.

Achire zotsatira za mankhwala

Chochita chofunikira kwambiri cha Apidra ndi kuyendetsa bwino kwa kagayidwe kazigazi m'magazi, insulin imatha kutsitsa shuga, potero imapangitsa kuyamwa kwake ndi zotumphukira:

Insulin imalepheretsa kupanga shuga mu chiwindi cha wodwalayo, adipocyte lipolysis, proteinol, ndikuwonjezera kupanga mapuloteni.

M'maphunziro omwe amachitika pa anthu athanzi komanso odwala matenda a shuga, zidapezeka kuti kupindika kwa glulisin kumathandizira msanga, koma kwakanthawi kochepa, poyerekeza ndi insulin yaumunthu.

Ndi subcutaneous makonzedwe a mankhwala, hypoglycemic zotsatira zidzachitika mkati 10 mpaka mphindi, ndi jekeseni wa intravenous zoterezi zimakhala zofanana mu mphamvu kuchitira anthu insulin. Chipinda cha Apidra chimadziwika ndi ntchito ya hypoglycemic, yomwe imafanana ndi gawo la insulin ya anthu osungunuka.

Apidra insulin imayendetsedwa kwa mphindi 2 chakudya chisanachitike, chomwe chimapangitsa kuti pakhale vuto la postprandial glycemic, lofanana ndi insulin ya anthu, yomwe imaperekedwa mphindi 30 asanadye. Tiyenera kudziwa kuti kuwongolera kotereku ndiko kwabwino koposa.

Ngati glulisin imayikidwa pakatha mphindi 15 itatha kudya, imatha kuwongolera kuchuluka kwa shuga m'magazi, omwe amafanana ndi insulin ya anthu omwe amapatsidwa mphindi ziwiri asanadye.

Insulin imakhala m'magazi kwa mphindi 98.

Milandu yama bongo osokoneza bongo ndi zovuta zina

Nthawi zambiri, wodwala yemwe ali ndi matenda ashuga amatha kukhala osafunikira monga hypoglycemia.

Nthawi zina, mankhwalawa amachititsa kuti pakhale zotupa pakhungu ndipo amatupa pamalo a jekeseni.

Nthawi zina ndimafunso a lipodystrophy mu shuga mellitus, ngati wodwalayo sanatsate malangizowo pakusinthana kwa malo a jakisoni a insulin.

Zina zomwe zimayambitsa matendawa ndi monga:

1. chokoletsa, urticaria, matupa a chifuwa chachikulu (pafupipafupi),
2. chifuwa cholimba (chosowa).

Ndi chiwonetsero chazomwe zimachitika mthupi mwake, pamakhala ngozi pa moyo wa wodwalayo. Pachifukwa ichi, ndikofunikira kuti mukhale ndi chidwi ndi thanzi lanu ndikumvera zosokoneza zake zazing'ono.

Pakakhala vuto losokoneza bongo, wodwalayo amakhala ndi vuto loti azisinthasintha. Pankhaniyi, chithandizo chikusonyezedwa:

• hypoglycemia - kugwiritsa ntchito zakudya zomwe zimakhala ndi shuga (odwala matenda ashuga ayenera kukhala nawo nthawi zonse)
• kwambiri hypoglycemia ndi kutaya chikumbumtima - kuyimitsidwa kumachitika ndi kuperekera 1 ml ya glucagon subcutaneily kapena mu mnofu, glucose amatha kutumikiridwa kudzera mu minyewa (ngati wodwalayo sayankha glucagon).

Wodwala akangobwerera kumene, ayenera kudya zakudya zochepa.

Zotsatira za hypoglycemia kapena hyperglycemia, pamakhala mwayi woti wodwalayo azikhala wokhazikika, asinthe kuthamanga kwa zochitika zama psychomotor. Izi zimadzetsa chiwopsezo poyendetsa magalimoto kapena machitidwe ena.

Chidwi chachikulu chiyenera kuperekedwa kwa odwala matenda ashuga omwe ali ndi vuto locheperapo kapena osazindikira kwenikweni zomwe zingachitike. Ndikofunikanso pakanthawi kambiri ka shuga kakang'ono kwambiri.

Odwala otere ayenera kusankha pazomwe angayendetsere magalimoto ndi machitidwe ake pawokha.

Malangizo ena

Momwe amagwiritsidwira ntchito limodzi ndi insulin Apidra SoloStar ndi mankhwala ena, kuwonjezeka kapena kuchepa kwa chiyembekezo cha chitukuko cha hypoglycemia kumatha kuchitika, ndi chikhalidwe kuphatikiza njira izi:

1. matenda amkamwa,
2. ACE zoletsa
3. mafupa
4. Ma Disopyramides,
5. Mao zoletsa
6. Fluoxetine,
7. Pentoxifylline
8. salicylates,
9. Propoxyphene,
10. sulfonamide antimicrobials.

Zotsatira za hypoglycemic zimatha kuchepa kangapo ngati insulin glulisin imayikidwa limodzi ndi mankhwala: diuretics, phenothiazine, mahomoni a chithokomiro, proteinase inhibitors, antipsychotropic, glucocorticosteroids, Isoniazid, Phenothiazine, Somatropin, sympathomimetics.

Pentamidine wa mankhwala pafupifupi amakhala ndi hypoglycemia ndi hyperglycemia. Ethanol, mchere wa lithiamu, beta-blockers, mankhwala a Clonidine amatha kukhala ndi mphamvu ndikuchepetsa mphamvu ya hypoglycemic.

Ngati kuli kofunikira kusamutsa munthu wodwala matenda a shuga kupita ku mtundu wina wa insulin kapena mtundu wina wa mankhwala, kuyang'aniridwa ndi dokotala ndikofunikira. Ngati mulingo wambiri wa insulin wagwiritsidwa ntchito kapena wodwala akangosankha zochita kuti asankhe kusiya kumwa, izi zipangitsa kuti:

Zinthu zonsezi zimawopseza wodwalayo.

Ngati kusinthika kwazomwe zikuchitika panjira yamagalimoto, kuchuluka ndi kuchuluka kwa chakudya chamagwiritsidwe, kusintha kwa Apidra insulin kungafunike. Zochita zolimbitsa thupi zomwe zimachitika mukangodya chakudya zimatha kuwonjezera mwayi wa hypoglycemia.

Wodwala yemwe ali ndi matenda ashuga amasintha kufunika kwa insulini ngati ali ndi matenda ochulukirapo kapena odwala. Mtunduwu umatsimikiziridwa ndikuwunika, madokotala komanso odwala.

Apidra insulin imayenera kusungidwa m'malo amdima, omwe ayenera kutetezedwa kwa ana kwa zaka ziwiri. Kutentha kwabasi kosungira mankhwalawa kumachokera ku madigiri 2 mpaka 8, ndizoletsedwa kuti amasule insulin!

Pambuyo pakuyamba kugwiritsa ntchito, makatiriji amasungidwa pamtunda wosaposa 25 digiri, ali oyenera kugwiritsidwa ntchito kwa mwezi umodzi.

Zambiri za Apidra insulin zimaperekedwa mu kanema munkhaniyi.

Apidra, malangizo ogwiritsira ntchito

Insulin Apidra SoloStar idakonzedwa kuti ikwaniritse sc sc, yomwe imachitika pasanadutse (0-15 mphindi) kapena itangotha ​​chakudya.

Mankhwala ayenera kugwiritsidwa ntchito mu regimens achire, kuphatikizapo kugawana insulin yayitali (mwina analog) kapena lalitali magwiridwe antchito, komanso ofanana ndi m`kamwa hypoglycemic mankhwala machitidwe.

Malangizo a Apidra mlingo amatsimikiziridwa payekhapayekha.

Kukhazikitsidwa kwa Apidra SoloStar kumachitika pogwiritsa ntchito jakisoni wa sc, kapenakulowetsedwa kosalekezaanachita subcutaneous mafuta ntchito dongosolo la pampu.

Kuwongolera sc kumachitika paphewa, khoma lam'mimba (kutsogolo) kapena ntchafu. Kulowetsedwa amachitika mu subcutaneous mafuta m'dera khoma lamimba (kutsogolo). Malo a subcutaneous makina (ntchafu, khoma lam'mimba, phewa) ayenera kusinthidwa ndi jekeseni lililonse lotsatira. Pothamanga mayamwidwe komanso nthawi yodziwika ndi mankhwalawa imatha kutengera zomwe zachitika, kusintha kwina, komanso malo oyang'anira. Kulowetsa khoma la m'mimba kumathamanga mayamwidwepoyerekeza ndi kuyambitsa ndi ntchafu kapena phewa.

Popanga jakisoni, njira zonse zofunika kuzisamala ziyenera kuonedwa kuti musagwiritsidwe ntchito mankhwala mwachindunji mitsempha yamagazi . Pambuyo jekeseni oletsedwa kutikita minofum'malo oyambitsa. Odwala onse omwe akugwiritsa ntchito Apidra SoloStar amayenera kufunsidwa njira yoyenera yoyendetsera. insulin.

Kuphatikiza Apidra SoloStar kumaloledwa kokha ndi isophane insulin. Mukasakaniza mankhwalawa, Apidra iyenera kuyimiriridwa kaye syringe. Kuwongolera kwa SC kuyenera kuchitika pokhapokha atasakanikirana. Mu / jakisoni wa mankhwala osakanikirana sangathe.

Ngati ndi kotheka, yankho la mankhwalawa limatha kuchotsedwa mu cartridge yomwe ikuphatikizidwa ndi cholembera ndikugwiritsidwa ntchito chipangizo pampulakonzedwa kuti lipitirire kulowetsedwa. Pankhani yakukhazikitsa kwa Apidra SoloStar ndi dongosolo kulowetsedwa, kusakanikirana kwake ndi mankhwala ena aliwonse saloledwa.

Mukamagwiritsa ntchito kulowetsedwa ndi thanki yomwe imagwiritsidwa ntchito ndi Apidra, iyenera kusinthidwa osachepera maola 48 motsatira kutsatira malamulo onse. Malangizowo atha kukhala osiyana ndi omwe adafotokozedwera zida zapampukomabe, kuphedwa kwawo ndikofunikira kwambiri kuti achite zinthu moyenera kulowetsedwandi kupewa mapangidwe oyipa.

Odwala omwe akupitilira kulowetsedwa kwa apidra s / d ayenera kukhala ndi njira zina zopangira jakisoni, komanso kuphunzitsidwa njira zoyenera zogwiritsira ntchito (kuwonongekachipangizo pampu).

Nthawi kulowetsedwa kosalekeza Apidra, kulakwitsa kwa kulowetsedwa pampu idayamba, kuphwanya ntchito yake, komanso zolakwitsa pamankhwala nawo, zimatha kukhala chifukwa cha hyperglycemia, matenda ashuga ketoacidosis ndi ketosis. Pothana ndi mawonekedwe awa, ndikofunikira kukhazikitsa chifukwa cha chitukuko ndikuchithetsa.

Kugwiritsa ntchito cholembera cha SoloStar Syringe ndi Apidra

Musanagwiritse ntchito koyamba, cholembera cha SoloStar chimayenera kuchitidwa kwa maola awiri firiji.

Musanagwiritse ntchito cholembera, muyenera kuwunika mosamala cartridge yomwe ili mmenemo, zomwe ziyenera kukhala wopanda utoto, chowonekeraosaphatikizira zowoneka nkhani yakunja yakunja (akumbutse kusasinthika kwamadzi).

Ntchito Zogwiritsa ntchito SoloStar Syringe sizingagwiritsenso ntchito ndipo ziyenera kutayidwa.

Pofuna kupewa matendaMunthu m'modzi yekha ndi yemwe angagwiritse ntchito cholembera chimodzi popanda kuchisintha kwa munthu wina.

Pogwiritsa ntchito cholembera chatsopano chilichonse, sinthanitsani mosamala ndi singano yatsopano (yogwirizana ndi SoloStar) ndikugwirira kuyesa chitetezo.

Pochita ndi singano, chisamaliro chachikulu chiyenera kuchitika kuti mupewe kuvulalandi mwayi zopatsirana kusamutsa.

Kugwiritsira ntchito zolembera za syringe kuyenera kupewedwa ngati kuwonongeka, komanso ngati osatsimikizika pantchito yawo moyenera.

Ndikofunikira nthawi zonse kukhala ndi cholembera chopanda chilichonse mu katundu, ngati chitha kapena kuwonongeka koyambirira.

Cholembera cha syringe chimayenera kutetezedwa ku dothi ndi fumbi, ndizovomerezeka kupukusa kunja kwake nsalu yonyowa. Sitikulimbikitsidwa kumiza cholembera madzimadzi, kuchapakapena mafutapopeza izi zitha kuyipitsa.

Syringe cholembera SoloStar yotetezeka imagwira ntchito, mosiyana dosing yeniyeni yankho ndipo imafunikira kuisamalira mosamala. Mukamachita manambala onse ndi cholembera, ndikofunikira kupewa chilichonse chomwe chitha kuwononga. Ngati mukukayikira kuti ikhoza kugwira ntchito, gwiritsani ntchito cholembera china.

Nthawi yomweyo jekeseni isanachitike, onetsetsani kuti analimbikitsa insulinpoyang'ana cholembera pa cholembera cholembera. Mukachotsa chipewa mu syringe cholembera, muyenera kutero kuyang'ana kowoneka Zomwe zili mkati mwake, ndikukhazikitsa singano. Chololedwa kokha wopanda utoto, chowonekerachofanana ndi madzi mokhazikika komanso kuphatikiza ina zolowa zakunja yankho insulin. Pakhungu lililonse lomwe latuluka, ayenera kugwiritsa ntchito singano yatsopano, yomwe imayenera kukhala yosabala komanso yoyenera cholembera.

Pamaso jakisoni, onetsetsani kuyesa chitetezo, yang'anani ntchito yoyenera ya cholembera ndi singano yomwe idayikidwapo, ndikuchotsanso yankho thovu (ngati alipo).

Pachifukwa ichi, pomwe zingwe zamkati ndi zamkati za singano zimachotsedwa, muyeso wa yankho lofanana ndi 2 PIECES umayesedwa. Kuloza singano ya cholembera kuti isungunuke molunjika, ikani pang'ono pakatoni ndi chala chanu, kuyesera kuti musunthe chilichonse thovu ku singano yoikika. Dinani batani lomwe lakonzedwa kuti mupereke mankhwala. Ngati iwoneka kumapeto kwa singano, titha kuganiza kuti cholembera chimagwira monga momwe timayembekezera. Ngati izi sizingachitike, bwerezani zomwe zidatchulidwa pamwambapa mpaka zotsatira zomwe mukufuna zitheke.

Pambuyo kuyesapachitetezo, zenera la dengalo liyenera kuwonetsa mtengo "0", kenako mlingo womwe ungafunike ukhoza kukhazikitsidwa. Mlingo wothandizidwa ndi mankhwalawa uyenera kuyesedwa ndi kulondola kwa 1 UNIT, pamlingo kuchokera 1 UNIT (osachepera) mpaka 80 UNITS (pazambiri). Ngati ndi kotheka, mlingo wopitilira 80 amayiti umachitika jekeseni awiri kapena kuposa.

Mukabayidwa, singano yomwe imayikidwapo cholembera iyenera kuyikiridwa mosamalapansi pa khungu. Chingwe cha cholembera chomwe chimayikidwa pakukhazikitsa njira yothetsera vutoli chiyenera kukanikizidwa kwathunthu ndikukhala m'malo ano kwa masekondi 10 mpaka singano itachotsedwa, zomwe zimatsimikizira kukonzekera kwathunthu kwa mankhwala.

Pambuyo pa jekeseni, singano imayenera kuchotsedwa ndikuchotsedwa. Mwanjira imeneyi, chenjezo la kuperekedwa limaperekedwa. matendandi / kapena kuipitsama cholembera a syringe, komanso mankhwala opatsirana ndi mpweya ndikulowa mu cartridge. Mukachotsa singano yomwe imagwiritsidwa ntchito, cholembera cha SoloStar chizikhala chotseka ndi chipewa.

Pochotsa ndi kutaya singano, ndikofunikira kutsogoleredwa ndi malamulo ndi njira zapadera (mwachitsanzo, njira yokhazikitsa chipewa cha singano ndi dzanja limodzi), kuti muchepetse chiopsezo cha ngozikomanso kupewa matenda.

Bongo

Pankhani yamaulamuliro ochuluka insulinzitha kuchitika hypoglycemia.

Ndi kuwala hypoglycemia, mawonekedwe ake oyipa amatha kuyimitsidwa ndi chakudya shuga wokhalaZogulitsakapena shuga. Odwala ndi matenda ashuganthawi zonse amalimbikitsa kunyamula makeke, maswitizidutswa shugakapena msuzi wokoma.

Zizindikiro zazikulu hypoglycemia(kuphatikizazovuta zamitsempha, kukokana, kulephera kudziwa,) iyenera kuyimitsidwa ndi anthu achiwiri (ophunzitsidwa mwapadera) pochita jakisoni wa / m kapena s / c kapena poyambitsa yankho. Ngati ntchito glucagonsanapereke chifukwa kwa mphindi 10-15, sinthani ku iv dextrose.

Wodwala yemwe adabwera kuzindikiraamalimbikitsa kudya kwambiri chakudyaimani pamapeto kuti mubwereze hypoglycemia.

Kuti mudziwe zomwe zimayambitsa kwambiri hypoglycemiandi kupewa kukula kwake mtsogolo, ndikofunikira kuyang'ana wodwalayo mkati chipatala.

Malangizo apadera

Wodwala insulinchomera china chopangira kapena njira ina insulin ziyenera kuchitika moyang'aniridwa ndi ogwira ntchito zachipatala, pokhudzana ndi kufunika kosintha mtundu wa mankhwala, chifukwa cha kupatuka insulin ndendemtundu wake (insulin isophane, sungunukaetc.), mawonekedwe (munthu, chinyama) ndi / kapena njira yopangira. Kusintha kungakhale kofunikira limodzi hypoglycemicmankhwala ndi pakamwa mitundu. Kusiya mankhwala kapena mlingo wokwanira insulinmakamaka odwala shuga achinyamatazingayambitse matenda ashuga ketoacidosisndi hyperglycemiakuyimira chiopsezo ku moyo wa wodwalayo.

Nthawi yatha hypoglycemiachifukwa cha kuchuluka kwa mapangidwe insulin kwenikweni ogwiritsa ntchito mankhwala, ndipo chifukwa cha izi, amatha kusintha posintha njira zochizira. Kusintha kwazomwe zimapangidwa hypoglycemiakapena kuwapangitsa kuti asatchulidwe, kuphatikiza: kulimbitsakupezeka kwa nthawi yayitali matenda ashugakukhalapo matenda ashuga a m'mimbazisinthe insulinkumwa mankhwala ena (i.e.opanga beta).

Kusintha insulinMlingo ungakhale wofunikira mukachulukitsa wodwala zolimbitsa thupi kapena kusintha zakudya zanu zatsiku ndi tsiku. Kuchita masewera olimbitsa thupi mukangodya kumene kumakulitsa vuto lanu hypoglycemia. Mukamagwiritsa ntchito kuthamanga insulin chitukuko hypoglycemiazikuyenda mwachangu.

Zosalipidwa Hyper- kapena hypoglycemicmawonetseredwe amatha kuyambitsa chitukuko, kulephera kudziwa, kapena ngakhale kufa.

insulin yamunthu ndi insulin glulisin mogwirizana fetal/fetalchitukuko, kumene wa mimba, ntchito yoyang'anira ndi pambuyochitukuko.

Gawirani Apidra woyembekezeraAzimayi ayenera kusamala ndikuwonetsetsa kuti plasma ikuwayang'anira kuchuluka kwa shuga ndi kuwongolera.

Amimbaazimayi okhala ndi matenda ashuga ayenera kudziwa kuchepetsa komwe kukufunika insulinkupyola Ine trimester wa mimbaonjezerani II ndi III trimesterkomanso kuchepa msanga pambuyo.

Kusankha insulin glulisin mkaka wa mayi woyamwitsa suukhazikika. Ndi kugwiritsidwa ntchito panthawiyo, zitha kukhala zofunika kusintha mtundu wa mankhwalawo.

Wamtundu waifupi insulin.

Kukonzekera: APIDRA ®
Chithandizo chogwira ntchito: insulin glulisine
Code ya ATX: A10AB06
KFG: Insulin yofulumira ya anthu
Reg. nambala: LS-002064
Tsiku lolembetsa: 10/06/06
Mwini reg. acc.: AVENTIS PHARMA Deutschland GmbH

FOMU YA DOSAGE, KULIMA NDI KUSANGALATSA

Zotsatira zoyipa zomwe zimayesedwa kuchipatala zoyesedwa ndi kuperekera mankhwalawa zalembedwa pansipa malinga ndi machitidwe a ziwalo ndi dongosolo loti achepetse. Pofotokozera pafupipafupi zomwe zimachitika, njira zotsatirazi zimagwiritsidwa ntchito: nthawi zambiri -> 10%, nthawi zambiri -> 1% ndi 0,1% ndi 0,01% ndi KUSUNGA KWAMBIRI

Hypersensitivity kuti insulin glulisin kapena chilichonse cha mankhwala.

Ndi kusamala ayenera kugwiritsidwa ntchito pa nthawi yoyembekezera.

KULAMBIRA NDI KUDZIPEREKA

Mukamapereka mankhwala pakumwa pakati, muyenera kuisamalira. Kuwunikira mosamala kuchuluka kwa shuga m'magazi kumafunika. Palibe zambiri zakuchipatala pakugwiritsa ntchito insulin glulisin pa nthawi ya pakati.

Odwala omwe ali ndi matenda osokoneza bongo (kuphatikizapo chizolowezi) amafunika kukhalabe ndi chitetezo chokwanira pa nthawi yonse yobereka. Mu trimester yoyamba ya mimba, kufunika kwa insulin kumatha kuchepa, ndipo muyezo wachiwiri ndi wachitatu, monga lamulo, utha kuwonjezeka. Pambuyo pobadwa, insulini imafuna kuchepa mwachangu.

Mu kafukufuku woyesera Panalibe kusiyana pakubala pakati pa zovuta za insulin glulisin ndi insulin yaumunthu pamimba, kukulira kwa mluza ndi mwana wosabadwayo, kubala kwa mwana ndi kubereka.

Sizikudziwika ngati insulin glulisin yachotsedwa mkaka waumunthu, koma insulin ya munthu siyikupukusidwa mkaka waumunthu ndipo simumizidwa ndi kumeza.

Pa mkaka wa m'mawere (yoyamwitsa), kusintha kwa insulin ndi zakudya kungafunike.

Kusamutsa wodwala ku mtundu wina wa insulin kapena insulini ina kuchokera kwa wopanga wina uyenera kuchitika moyang'aniridwa ndi achipatala, monga kukonza mankhwala omwe akupitilira angafunike. Kugwiritsa ntchito Mlingo wambiri wa insulin kapena kusiya chithandizo chokwanira, makamaka kwa odwala matenda amishuga 1, kungayambitse matenda a hyperglycemia ndi matenda ashuga a ketoacidosis, mikhalidwe yomwe ikhoza kukhala pangozi.

Nthawi ya kukonzekera kwa hypoglycemia kutengera mphamvu ya mankhwalawa chifukwa mankhwalawa angagwiritsidwe ntchito, ndipo potero, angasinthe ndikusintha kwa regimen yothandizira. Mikhalidwe yomwe ingasinthe kapena kuchepera kutchulira koyambirira kwa hypoglycemia imaphatikizapo kukhalapo kwa matenda a shuga, kulimbitsa insulin, kukhalapo kwa matenda a shuga, kugwiritsa ntchito mankhwala ena (monga beta-blockers), kapena kusamutsa wodwala kuchokera ku insulin yakuchokera kwa nyama kupita ku insulin yaumunthu.

Malangizo a insulin Mlingo ungafunikire posintha boma la zolimbitsa thupi kapena chakudya. Kuchita masewera olimbitsa thupi mutangotha ​​kudya kungakulitse chiopsezo cha hypoglycemia. Poyerekeza sungunuka wa insulin ya anthu, hypoglycemia imatha kumera pambuyo pobayira jakisoni wa insulin.

Kuchuluka kwa hypoglycemic kapena hyperglycemic komwe sikunachitike kungakuchititseni kuti musakhale ndi chikumbumtima, chikomokere, kapena kufa.

Kufunika kwa insulini kungasinthe ndi matenda oyanjananso kapena kutaya mtima kwambiri.

Zizindikiro Palibe chidziwitso chapadera cha kuchuluka kwa insulin glulisin, hypoglycemia ya zovuta zosiyanasiyana zomwe zimachitika.

Chithandizo: magawo a hypoglycemia wofatsa amatha kuyimitsidwa ndi shuga kapena zakudya zomwe zili ndi shuga.Chifukwa chake, tikulimbikitsidwa kuti odwala matenda ashuga nthawi zonse azikhala ndi shuga, maswiti, makeke kapena mandimu okoma zipatso. Ndime za hypoglycemia yayikulu, pomwe wodwalayo atha kuzindikira, akhoza kuyimitsidwa ndi i / m kapena s / c pomupereka kwa 0.5-1 mg wa glucagon kapena iv ndi dextrose (glucose) Ngati wodwala sayankha glucagon kwa mphindi 10-15, ndikofunikira kuyambitsa intravenous dextrose. Pambuyo pozindikira, tikulimbikitsidwa kupatsa wodwala zamkati mkati kuti tipewe kubwerezanso kwa hypoglycemia. Pambuyo pokonzekera glucagon, wodwalayo amayenera kuthandizidwa kuchipatala kuti adziwe zomwe zimayambitsa hypoglycemia yayikulu ndikuletsa kutulutsa kwa zina.

Kafukufuku wokhudzana ndi kukhudzana kwa mankhwala a pharmacokinetic kwa mankhwala sanachitike. Kutengera ndi kudziwa komwe kumanenedwa ndimankhwala ena ofanana, kuwoneka kwa mgwirizano wachipatala kwambiri sikungachitike. Zinthu zina zimatha kuthana ndi kagayidwe ka glucose, kamene kangafunikire kusintha kwa insulin glulisin makamaka kuwunika mosamala chithandizo ndi mkhalidwe wa wodwalayo.

Mukagwiritsidwa ntchito limodzi, othandizira pakamwa a hypoglycemic, ma ACE inhibitors, disopyramids, fibrate, fluoxetine, MAO inhibitors, pentoxifylline, propoxyphene, salicylates ndi sulfonamide antimicrobials amatha kupititsa patsogolo hypoglycemic zotsatira za insulin ndikuwonjezera chidwi cha hypoglycemia.

Ndi kuphatikiza kwa GCS, danazole, diazoxide, diuretics, isoniazid, phenothiazine, zotengeka, somatropin, sympathomimetics (mwachitsanzo, epinephrine / adrenaline /, salbutamol, terbutaline), mahomoni a chithokomiro, estrojeni, progestine (e.g. contracitors. Mankhwala (mwachitsanzo, olanzapine ndi clozapine) amatha kuchepetsa kuchuluka kwa insulin.

Beta-blockers, clonidine, mchere wa lithiamu kapena ethanol amatha kukhala wowonjezera kapena kufooketsa mphamvu ya hypoglycemic ya insulin. Pentamidine imatha kuyambitsa hypoglycemia kenako hyperglycemia.

Mukamagwiritsa ntchito mankhwala omwe ali ndi ntchito ya chisoni (beta-blockers, clonidine, guanethidine ndi reserpine), zizindikiro za reflex adrenergic activation ndi hypoglycemia zitha kukhala zosatchulika kapena kusapezeka.

Chifukwa cha kusowa kwa maphunziro othandizira, insulin glulisin sayenera kusakanikirana ndi mankhwala ena onse kupatula is is-insulin yaumunthu.

Pakuperekedwa ndi pampu kulowetsedwa, Apidra sayenera kusakanikirana ndi mankhwala ena.

PHARMACY HOLIDAY MALANGIZO

Mankhwala ndi mankhwala.

MITU YA NKHANI NDI ZOTHANDIZA ZA STORAGE

Makatiriji a OptiKlik ndi makatoni ama cartridge ziyenera kusungidwa kuti zisachitike ndi ana, kutetezedwa ndi kuwala kwa 2 2 mpaka 8 ° C, osazizira.

Mukayamba kugwiritsa ntchito makatiriji ndi makina a cartridge a OptiClick ziyenera kusungidwa kuti zisachitike ndi ana, kutetezedwa ndi kuwala pamtunda wosaposa 25 ° C.

Kuti muteteze ku kuwala, sungani makatoni a OptiKlik ndi makatoni ama cartridge awo.

Moyo wa alumali ndi zaka 2. Alumali moyo wa mankhwalawa katiriji, OptiClick cartridge system mukatha kugwiritsa ntchito masabata 4. Ndikulimbikitsidwa kuyika tsiku lomwe kuchotsedwa kwa mankhwalawo kulembetsa.

Mtundu umodzi wa insulini womwe umapezeka m'misika yama shopu ndi insulin apidra. Ichi ndi mankhwala apamwamba kwambiri, omwe, malinga ndi zomwe dokotala amupatsa, angagwiritsidwe ntchito ngati amtundu wa matenda ashuga ngati milandu yawo yomwe siipangidwe mokwanira ndipo iyenera kuvulazidwa. Mankhwala amaperekedwa ndi mankhwala ndipo amafunikira kuwerengedwa mosamala. Amadziwika ndi kukhathamiritsa kwambiri akagwiritsidwa ntchito moyenera.

Zizindikiro, contraindication

Mankhwalawa amagwiritsidwa ntchito ngati matenda a shuga 1 ngati cholowa m'malo mwa insulin yachilengedwe, yomwe samapangidwa mu matendawa (kapena amapangidwa mosakwanira). Itha kuperekedwanso matenda amtundu wachiwiri pokhapokha ngati kukana (chitetezo chokwanira) kumamwa mankhwala a glycemic kukhazikitsidwa.

Ali ndi insulin apidra ndi contraindication. Monga mankhwala aliwonse otere, sangatengedwe ndi chizolowezi kapena kupezeka mwachindunji kwa hypoglycemia. Kusagwirizana ndi chinthu chachikulu chomwe mankhwalawo amagwira kapena zomwe zimapangidwira zimathandizanso kuti ziyimitsidwe.

Kugwiritsa

Malamulo oyambira kuphatikiza mankhwala ali motere:

1. Zoyambitsidwa isanakwane (osapitirira mphindi 15) kapena mukangodya chakudya,
2. Iyenera kugwiritsidwa ntchito limodzi ndi ma insulin omwe akhala akuchita nthawi yayitali kapena mtundu womwewo wa mankhwala amkamwa,
3. Mlingo umayikidwa mosamalitsa payekhapayekha pa nthawi yoonana ndi adokotala.
4. Amayendetsedwa mosasamala,
5. Masamba obayira omwe amakonda: ntchafu, pamimba, minofu yolimba, matako,
6. Muyenera kusinthitsa mawebusayiti,
7. Akayambitsidwa kudzera khoma lam'mimba, mankhwalawo amawamwa ndipo amayamba kuchita zinthu mwachangu,
8. Musamanunitsire jakisoni pamalo operekera mankhwala,
9. Samalani kuti musawononge mitsempha ya magazi,
10. Ngati kuphwanya mtundu wa ntchito kwa impso, ndikofunikira kuchepetsa ndi kupanganso mulingo wa mankhwalawa.
11. Pankhani ya vuto la chiwindi losokoneza, mankhwalawa ayenera kugwiritsidwa ntchito mosamala - maphunziro ngati awa sanachititsidwe, koma pali chifukwa chokhulupirira kuti mulingo wofunikira mu nkhani iyi uyenera kuchepetsedwa, chifukwa kufunika kwa insulin kumachepa chifukwa cha kuchepa kwa glucogeneis.

Musanayambe kugwiritsa ntchito, muyenera kupita kwa dokotala kuti muwerenge kuchuluka kwa mankhwalawa

Epidera wa mankhwalawa ali ndi kufanana pakati pa insulin. Awa ndi ndalama zokhala ndi zomwe zimapangira chimodzimodzi, koma zokhala ndi dzina lina. Amathandizanso thupi. Izi ndi zida monga:

Mukasintha kuchoka ku mankhwala kupita ku wina, ngakhale analogue, muyenera kufunsa dokotala.

About Apidra Insulin

Njira zochizira matenda a shuga ndizothandiza kwambiri ndipo, nthawi yomweyo, kutali ndi zonsezo zimalekeredwa mosavuta ndi thupi la munthu. Odalirika komanso abwino kwambiri pankhaniyi ndi ma insulin osakhalitsa. Amathandizira odwala matenda ashuga komanso kuti azitha kubwezeretsa thupi komanso kugaya chakudya mwachangu. Kodi ndizotheka kunena chiyani za Apidra insulin?

Pa kapangidwe ndi mawonekedwe amasulidwe

Chifukwa chake, "Apidra" ndi insulin yochepa. Kuchokera pakuwona mkhalidwe wakuphatikiza - iyi ndi yankho. Amapangidwira makonzedwe apadera okha komanso amawonekera bwino komanso opanda utoto (nthawi zina, mthunzi wina ukadalipo).

Gawo lake lalikulu, lomwe limapezeka mulifupi kwambiri, liyenera kutengedwa kuti ndi insulini yotchedwa glyzulin, yomwe imadziwika ndi kuchitapo kanthu mwachangu komanso kwakanthawi. Othandizira ndi:

• kresol
• trometamol,
• sodium kolorayidi
• polysorbate ndi ena ambiri, amapezekanso pa.

Onsewa amaphatikizika pamodzi amapanga popanda kukayikira mankhwala apadera omwe angapezeke ndi mtundu uliwonse wa matenda ashuga: woyamba ndi wachiwiri. Apidra insulin imapangidwa mwa ma cartridge apadera opangidwa ndi galasi lopanda utoto.

Zokhudza zotsatira zamankhwala

Kodi Apidra amakhudza bwanji shuga?

Glulin insulin ndi analogue yowonjezera ya anthu.Monga mukudziwa, ikhoza kufananizidwa ndi mphamvu kuti isungunuke insulin yaumunthu, koma ndizodziwika kuti imayamba "kugwira ntchito" mwachangu kwambiri komanso imakhala nthawi yayifupi. Izi ndizothandiza kwambiri.

Chofunika kwambiri komanso chofunikira kwambiri osati pa insulin zokha, komanso pa analogues yake, imayenera kuganiziridwa nthawi zonse malinga ndi kusintha kwa shuga. Ma mahomoni operekedwa amachepetsa kuchuluka kwa shuga m'magazi, omwe amachititsa kuti shuga agwiritsidwe ntchito mothandizidwa ndi zotumphukira. Izi ndizowona makamaka kwa minofu yamafupa ndi minofu ya adipose. Apidra insulin imalepheretsanso kupanga shuga m'magazi. Kuphatikiza apo, imachepetsa njira zonse zomwe zimagwirizanitsidwa ndi lipolysis mu adipocytes, proteinolysis komanso imathandizira kuyenderana kwa mapuloteni.

Malinga ndi zotsatira za kafukufuku wambiri, zidatsimikizika kuti glulisin, chomwe chimakhala gawo lalikulu ndikulowetsedwa mphindi ziwiri asanadye chakudya, imatha kuperekanso chiwonetsero chofanana cha kuchuluka kwa shuga atatha kudya monga insulin yaumunthu yoyenera kusungunuka. Komabe, iyenera kuperekedwa kwa mphindi 30 chakudya chisanafike.

Zokhudza mlingo

Mfundo yofunikira kwambiri pakugwiritsa ntchito mankhwala aliwonse, kuphatikiza mayankho a insulin, iyenera kutengedwa ngati kumvetsetsa kwa Mlingo. Apidra tikulimbikitsidwa kuti ibweretsedwe posachedwa (kwa zero kochepa komanso kupitirira mphindi 15) musanadye kapena mutangodya.

Mankhwala angagwiritsidwe ntchito limodzi ndi enieni a mtundu wa hypoglycemic.

Momwe mungasankhire mlingo wa Apidra?

Apidra insulin dosing algorithm iyenera kusankhidwa payekha nthawi iliyonse. Zikachitika kuti matenda a impso akundikana, kuchepa kwa kufunikira kwa timadzi timeneti ndi kotheka.

Pa anthu odwala matenda ashuga omwe ali ndi vuto la chiwindi, kusowa kwa mapangidwe a insulin ndiwotheka kuchepa. Izi zimachitika chifukwa cha kuchepa mphamvu kwa glucose neogeneis komanso kuchepa mphamvu kwa kagayidwe kazinthu ka insulin. Zonsezi zimapereka tanthauzo lomveka, komanso zosafunikira, kutsatira mankhwala omwe akuwonetsedwa, ofunikira kwambiri pakulimbana ndi matenda a shuga.

About jakisoni

Mankhwala ayenera kuperekedwa ndi subcutaneous jakisoni, komanso kulowetsedwa mosalekeza. Ndikulimbikitsidwa kuti muchite izi mwapadera minofu yamafuta ochepa komanso mafuta pogwiritsa ntchito pulogalamu yapadera yopopera.

Jakisoni wotsekemera uyenera kuchitika mu:

Kubweretsa Apidra insulin pogwiritsa ntchito kulowetsedwa kosalekeza kapena minofu yamafuta kuyenera kuchitika m'mimba. Madera omwe samaba jakisoni wokha, komanso ma infusions omwe adapangidwa kale, akatswiri amalimbikitsa kusinthana wina ndi mnzake pakukhazikitsa kwatsopano kwa chinthucho. Zinthu monga dera lodzala, zochitika zolimbitsa thupi, ndi zina “zoyandama” zimatha kukhala ndi chiyambukiro pakukula kwa mayamwidwe ndipo, monga chotulukapo chake, pakubweretsa komanso kuchuluka kwake.

Momwe mungapangire jakisoni?

Kukhomeredwa pansi kwa khoma lachiberekero kumakhala chotsimikizika cha mayamwidwe ambiri kuposa kumizidwa m'malo ena a thupi. Onetsetsani kuti mwatsata malamulo osamala kuti musatenge mankhwala oikidwa m'mitsempha yamagazi.

Pambuyo kumayambiriro kwa insulin "Apidra" amaletsedwa kupukusa jakisoni. Anthu odwala matenda ashuga ayenera kuphunzitsidwanso njira yolondola ya jakisoni. Ichi ndi chinsinsi cha chithandizo chokwanira cha 100%.

Zokhudza malo osungirako ndi mawu

Pakulimbikitsa kwakukulu pakugwiritsa ntchito mankhwala aliwonse, munthu ayenera kukumbukira momwe alili.Chifukwa chake, makatoni ndi makina amtunduwu amayenera kusungidwa m'malo ocheperako kwa ana, omwe akuyenera kudziwikanso ndi chitetezo chachikulu ku kuwala.

Pankhaniyi, boma la kutentha liyeneranso kuonedwa, lomwe liyenera kuyambira madigiri awiri mpaka asanu ndi atatu.

Gawo silikhala louma.

Kugwiritsa ntchito makatiriji ndi makina a cartridge kuyambika, amafunikanso kusungidwa m'malo omwe ana sangathe kuwapeza omwe ali ndi chitetezo chodalirika osati kokha pakuwala kwa kuwala, komanso ku dzuwa. Nthawi yomweyo, zizindikiro za kutentha siziyenera kupitirira kutentha 25, apo ayi izi zitha kudziwa pa Apidra insulin.

Kuti mudziteteze modabwitsa ku mphamvu ya kuunika, ndikofunikira kuti musangopulumutsa makatiriji okha, koma akatswiri amalimbikitsa kachitidwe kameneka m'mapaketi awo, omwe amapangidwa ndi makatoni apadera. Alumali moyo wofotokozedwayo ndi zaka ziwiri.

Zonse zokhudza tsiku lotha ntchito

Moyo wa alumali wa mankhwala omwe amapezeka mu cartridge kapena dongosololi mutatha kugwiritsa ntchito masabata anayi. Ndikofunika kukumbukira kuti nambala yomwe ma insulin adatengedwa idalembedwa paphukusili. Ichi chidzakhala chitsimikizo chowonjezereka pakuchiza bwino kwa mtundu uliwonse wa matenda ashuga.

Zotsatira zoyipa

Zotsatira zoyipa zomwe zili ndi Apidra insulin ziyenera kudziwidwa padera. Choyamba, tikulankhula za chinthu monga hypoglycemia. Amapangidwa chifukwa chogwiritsa ntchito kwambiri ma insulin, ndiye kuti, omwe amapezeka kuti ali osowa kwambiri pakufunikira kwake.

Pa gawo la chamoyo monga metabolism, hypoglycemia imapangidwanso kwambiri. Zizindikiro zonse za mapangidwe ake zimadziwika mwadzidzidzi: pali thukuta lotentha, kunjenjemera ndi zina zambiri. Kuopsa pankhaniyi ndikuti hypoglycemia ichuluke, ndipo izi zitha kuchititsa kuti munthu afe.

Zomwe zimachitika mdera lanu ndizothekanso, zomwe ndi:

• Hyperemia,
• kudzikuza,
• kuyabwa kwakukulu (pamalo opangira jakisoni).

Mwinanso, kuphatikiza pa izi, kukulira kwa kusintha kwa ziwopsezo zomwe sizigwirizana, nthawi zina tikulankhula za urticaria kapena chifuwa cha thupi. Komabe, nthawi zina izi sizifanana ndi mavuto a pakhungu, koma kungokhala phokoso kapena zizindikiro zina zathupi. Mulimonsemo, zovuta zonse zomwe zaperekedwa zitha kupewedwa popanda kutsata malangizowo ndikukumbukira kugwiritsa ntchito bwino insulin monga Apidra.

Zokhudza contraindication

Contraindations yomwe ilipo kwa mankhwala aliwonse ayenera kupatsidwa chidwi chapadera. Izi ndizofunikira kwambiri kuti insulini imagwira ntchito pa 100%, kukhala njira yothandiza kwambiri yobwezeretsanso ndi kuteteza thupi. Chifukwa chake, zotsutsana zomwe zimaletsa kugwiritsa ntchito "Apidra" ziyenera kuphatikizapo hypoglycemia yokhazikika komanso chiwopsezo chowonjezeka cha insulin gluzilin, komanso zina zilizonse zamagulu a mankhwalawa.

Kodi amayi oyembekezera amatha kugwiritsa ntchito Apidra?

Ndi chisamaliro chapadera, kugwiritsa ntchito chida ichi ndikofunikira kwa amayi omwe ali pa nthawi iliyonse yoyembekezera kapena yoyamwitsa. Popeza mtundu wa insulin woperekedwa ndi mankhwala amphamvu, ungathe kuvulaza osati kwa mkaziyo, komanso kwa mwana wosabadwayo. Komabe, izi mwina zimakhala kutali ndi milandu yonse yokhudzana ndi matenda a shuga. Pankhaniyi, tikulimbikitsidwa kuti muyambe mwaonana ndi katswiri yemwe adzakuwonetsereni kuvomerezeka kwa kugwiritsa ntchito mankhwala a Apidra insulin, komanso kupereka mankhwala omwe akufuna.

Pazidziwitso zapadera

Mukamagwiritsa ntchito mankhwala aliwonse, ndikofunikira kuganizira zamagulu osiyanasiyana osiyanasiyana.Mwachitsanzo, kuti kusintha kwa matenda ashuga kukhala mtundu watsopano wa insulin kapena chinthu china chochokera pakukhudzidwa kwina kuyenera kuchitika moyang'aniridwa mwaluso kwambiri. Izi ndichifukwa choti pakhoza kufunikira kusintha kwamankhwala kwathunthu.

Kugwiritsa ntchito mankhwala osakwanira kapena kumayimitsa chithandizo, makamaka kwa anthu omwe ali ndi matenda a shuga 1, kungayambitse mapangidwe a hyperglycemia okha, komanso ketoacidosis yeniyeni. Awa ndi mikhalidwe yomwe mumakhala chiopsezo chenicheni ku moyo wa munthu.

Kusintha kwa Mlingo wa insulini kungakhale kofunikira kuti masinthidwe amachitidwe a kayendetsedwe ka kayendedwe ka mota kapena mukudya chakudya.

Nkhaniyi ndi yothandiza kwambiri. Ndikuganiza kuti anthu ambiri omwe akudwala matendawa athandiza. Zikomo posanthula momwe mungasungire mankhwalawa. Adotolo nayenso adalembera. Nkhaniyi idalembedwa zabwino zambiri, ndikhulupirira ndipo yandithandiza!

Apidra ndi insulin yocheperako yamunthu.

• Kodi mawonekedwe a Apidra insulin ndi mawonekedwe a kumasulidwa ndi chiyani?

Mankhwalawa amamasulidwa mwanjira yothetsera bwino, wopanda utoto, womwe umapangidwira makonzedwe pansi pa khungu. Gawo logwira la wothandizira ndi insulin glulisin.

Omwe amathandizira: madzi a jakisoni, m-cresol, sodium hydroxide, trometamol, polysorbate 20, sodium chloride, ana hydrochloric acid.

Mankhwalawa amaperekedwa m'matambula agalasi, amaikidwa m'matumba a chithuza. Makina a cartridge a OptiClick amayenera kusungidwa m'chipinda cha firiji, osatheka ndi ana, amatsutsana kuti amasule mankhwalawo.

Moyo wa alumali wa Apidra ndi zaka ziwiri. Kugulitsa mankhwalawa pambuyo pakugwiritsidwa ntchito koyambirira sikuyenera kupitilira milungu inayi. Ndikulimbikitsidwa kuyika chizindikiro pa chizindikiro. Siyani ndi mankhwala.

• Kodi mankhwala a Apidra insulin ndi ati?

Insulin glulisin imawonetsedwa ngati insulin ya anthu, potengera potency mankhwalawa ndi ofanana ndi insulin yaumunthu, koma kumayambira kumachitika mofulumira. Mankhwalawa amayang'anira kagayidwe kakang'ono ka thupi m'thupi, amachepetsa kuyika kwake, ndikulimbikitsa mayamwidwe ake ndi minofu ya adipose komanso minofu yamafupa.

Insulin imachepetsa lipolysis ndikuwonjezera kaphatikizidwe kazakudya. Ndi subcutaneous makonzedwe, kukula kwa hypoglycemic zotsatira kumachitika pafupifupi mphindi khumi.

• Kodi zizindikiro za Apidra insulin zikugwiritsa ntchito bwanji?

Mankhwalawa akuwonetsedwa kuti azigwiritsidwa ntchito mu matenda ashuga, ndipo amatha kutumizidwa kuyambira azaka zisanu ndi chimodzi.

• Kodi Apidra insulin contraindication amagwiritsa ntchito chiyani?

Pakati pa contraindication Apidra, malangizo ogwiritsira ntchito mndandanda monga mkhalidwe wa hypoglycemia, hypersensitivity kwa gawo logwira, ndipo mankhwalawa amagwiritsidwa ntchito mosamala pa nthawi yomwe ali ndi pakati.

• Kodi apidra insulin amagwiritsa ntchito ndi chiyani?

Mlingo wothandizira uyenera kusankhidwa ndi dokotala endocrinologist malinga ndi kuopsa kwa matenda a wodwalayo. Ndi kulephera kwa aimpso, komanso ndi matenda a impso, kufunika kwa insulin makonzedwe kumacheperachepera.

Kukhazikitsidwa kwa mankhwalawa kumachitika mozungulira mu ntchafu, pamimba kapena phewa, kapena mutha kuyendetsa kulowetsedwa kosalekeza mu mafuta osunthika a m'mimba. Ndikulimbikitsidwa kuti musinthe malo ena obayira.

Mlingo wa mayamwa umakhudzidwa ndi zochitika zolimbitsa thupi, komanso mikhalidwe ina. Kumwazika mwangozi mankhwala m'mitsempha yamagazi sikuyenera kuyikidwa pambali, ndipo malo a jekeseni sayenera kuzikitsidwa mwachindunji. Ndikofunikira kuphunzitsa wodwalayo njira yolondola ya jakisoni.

Cartridges amagwiritsidwa ntchito molingana ndi malamulo omwe afotokozedwa mu malangizo a mankhwala a Apidra.Makatoni opanda kanthu sayenera kudzazidwanso; ngati cholembera chawonongeka, sichigwiritsidwa ntchito.

Ndi bongo wa Apidra, dziko la hypoglycemic limakula. Pankhaniyi, ndikofunikira kuyambitsa kukonza kwa wodwala, mwachitsanzo, mutha kugwiritsa ntchito zinthu zomwe zimaphatikizapo shuga. Chifukwa chake, munthu amene akudwala matenda ashuga ayenera kukhala ndi chidutswa cha shuga kapena maswiti ochepa, kapena kukhazikika mu msuzi wabwino wa zipatso.

Mu hypoglycemia yayikulu, munthu amataya chikumbumtima, kenako glugagon kapena dextrose amayenera kutumikiridwa intramuscularly. Ngati pakadutsa mphindi 10 palibe zabwino, ndiye kuti mankhwalawa amaperekedwa kudzera m'mitsempha. Pambuyo pakuchiritsa matenda ake, ndikofunikira kusiya wodwala kuchipatala kwakanthawi kuti awoneke.

• Kodi mavuto a Apidra insulin ndi ati?

Hypoglycemia imadziwika kuti ndi vuto lalikulu la insulin, matendawa amakayamba ndi kukhazikitsa milingo yayikulu kwambiri ya Apidra. Izi, monga lamulo, zimachitika mwadzidzidzi, munthu amamva thukuta lozizira, khungu limasunthika, kutopa, kunjenjemera, kufooka kumachitika, njala, chisokonezo, kugona, kusokonezeka kwa maonedwe, nseru, palpitations amalowa.

Hypoglycemia imatha kupangitsa kuti munthu asamadziwe komanso kuti azigwira, ndipo nthawi zina amafa. Mwa zochita zakomweko, redness ndi kutupa zimatha kudziwika mwachindunji pamalo opangira jekeseni, nthawi zina, lipodystrophy imawonekera.

Thupi lawo siligwirizana mu mawonekedwe a urticaria, dermatitis, pakhoza kukhala kuyabwa ndi zotupa, komanso kukomoka. Muzovuta kwambiri, ziwonetsero zimaganiza kuti ndizochitika modzidzimutsa ndipo zimayamba kugwedezeka, zomwe zimafunikira chithandizo cham'tsogolo, popeza izi zimawopsa.

Kugwiritsa ntchito Mlingo wa insulin wokwanira kungayambitse matenda a ketoacidosis komanso kukula kwa hyperglycemia. Kuchita masewera olimbitsa thupi mutangotha ​​kudya kumawonjezera chiopsezo cha hypoglycemia.

• Kodi Apidra insulin analogu ndi chiyani?

Humalong ndi NovoRapid amatha kuwerengetsa mankhwala osokoneza bongo, asanagwiritse ntchito ndikofunikira kufunsa dokotala.

Apidra akuyenera kugwiritsidwa ntchito pokhapokha atasankhidwa ndi katswiri wa endocrinologist.