Momwe mungabayitsire - Fraxiparin?

Cholinga: kumayambiriro kwa mankhwala, kudutsa m'mimba.

Zowonetsa:

1. Kukhazikitsidwa kwa kuchuluka kwa mankhwala.

2. Kubweretsa njira zamafuta.

3. Chitani katemera.

4. Thandizo ladzidzidzi.

Zoyipa:

1. Zotsatira za mankhwalawa.

2. Kuphwanya umphumphu wa khungu pakhungu la jakisoni.

Malo a jekeseni wanjira:

Jakisoni wokhazikika amachitika m'malo amenewo amthupi momwe mulibe mitsempha yayikulu ndi mitsempha. Uku ndi kunja kwa phewa (pakati lachitatu), dera lothandiziranapo, malo owoneka m'mimba, kumbuyo kwa ntchafu.

Zida:

1. syringe yosalala, singano yotolera mankhwala.

2. Singano yosalala yotalika masentimita atatu kuti abwerere jakisoni wambiri mwa odwala omwe ali ndi mafuta ambiri ndipo 4-5 masentimita wosanjikiza kwambiri wamafuta.

3. Mipira itatu ya thonje yothira 70% mowa kapena AHD-2000.

4. thireyi lolembedwera "Zinthu zosapanga bwino."

5. Wobowola kapena chopukutira.

6. Tray yolembedwa "Zida zogwiritsidwa ntchito," ngati jekeseni ikuyenera kuchitidwa mu wodi.

7. 0,5% mowa yankho la chlorhexidine.

Heparin ndi mankhwala osokoneza bongo.

Heparin - imayikidwa kholo, mu 1 ml ya heparin imakhala ndi P000CES 5000., mumabotolo a 5 ml.

Heparin imayendetsedwa motsogozedwa ndi VSC (nthawi ya kuchuluka kwa magazi) komanso munthawi YOSAVUTA pakhungu la khoma lakunja lam'mimba kapena mu / m, mu / mkati.

Ndi VSK kuchokera mphindi 5. mpaka mphindi 8 - Magawo 10,000,

kuyambira 8 min. mpaka mphindi 12 - Magawo 5,000,

kuyambira mphindi 12 mpaka mphindi 15 - Magawo 2,5,000,

zopitilira mphindi 15 ASATSITSE!

1) Konzani manja anu jekeseni,

2) Sonkhanitsani syringe yolingana ndi 1 mpaka 5 ml, konzani singano ziwiri, imodzi yopanga mankhwala (yodziwika bwino), inayo kutalika kwa 20-30 mm, kuti mupeze jakisoni. Ikani singano yotseguka kwambiri pa syringe.

3) Chitani khosi lakumaso ndi mowa, fayilo yokhala ndi fayilo ya msomali, ndikuigwira ndi thonje lothonjetsedwa ndi mowa, thanani.

4) Jambulani mankhwalawo kuchokera ku zochulukirapo kapena bokosi, mutanyamula kandawo kapena vial pa singano ndi chala chanu. Kulandila kuchokera pa 1 mpaka 5 ml (monga adokotala adanenera),

5) Sinthani singano, ndikukweza syringe molunjika, mumasule ku mankhwala owonjezera ndi thovu, ndikuyang'ana momwe ilili.

6) Konzani mipira iwiri ya thonje yothira mowa.

7) Pemphani wodwalayo kuti amasule jakisoni wotsekera (kumbuyo kwake khoma lamkati lakumbuyo, ndikuthandizira 2 cm kuchokera ku navel). Chitani jakisoni wamowa ndi mowa, choyamba ndi mpira wa thonje pamalo akulu, kenako ndi enawo - mwachindunji tsamba la jekeseni. Osataya kunja mpira wachiwiri, koma mugwire m'manja ndi chala chanu chaching'ono.

8) Ndi dzanja lamanzere, pindani khungu, ndipo ndi dzanja lamanja, mutagwira syringe pakona kwambiri (pafupifupi 45º), ikani singano mozama 2/3 ya kutalika, kudula kwa singano kuyenera kupita kumtunda. Popanda kusintha syringe ku dzanja lina, lowetsani mankhwalawo. Ikani ubweya wachiwiri wa thonje ndi mowa pamalo opangira jakisoni ndipo, mutagwira singano ndi chala chanu, chotsani tiziwalo tating'onoting'ono tomwe tikuyenda mozungulira.

9) Ndi dzanja lanu lakumanzere ndi mpira wa thonje, pukutani pang'onopang'ono malo opaka jekeseni kuti agawire bwino mafuta osaneneka.

Ndi jakisoni wotsekemera, zovuta zimatheka: kulowa, kulowetsedwa, kusiya kachidutswa ka singano mu minofu yofewa, embolism, zovuta zina, kuyamwa kwina kwa mankhwalawa pansi pakhungu m'malo mwake.

Sanapeze zomwe mukuyang'ana? Gwiritsani ntchito kusaka:

Mawu abwino:Pofuna kuphunzira, mungathe kugula kena kake, koma osati zochulukirapo. 8724 - | 7134 - kapena werengani chilichonse.

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Onerani kanemayo

Odwala omwe amakonda thrombosis ndi mankhwala osokoneza bongo a fraxiparin. Ambiri ali ndi funso la momwe angagwiritsire ntchito. M'nkhaniyi tikuwuzani momwe mungapangire jakisoni wa fodya. Mankhwala osokoneza bongo a anticoagulant ndi m'badwo watsopano wa mankhwala. Ndi heparin wotsika kwambiri. Calcium calcium nadroparin ndi yogwira pophika kwa fraxiparin. Amakumana ndi antithrombin III, potero amawonjezera mphamvu yake yolepheretsa coagulation factor Xa, yomwe imayang'anira kusintha kwa prothrobin kukhala thrombin. Kugwiritsa ntchito kashiamu ya praporin sikuloleza kusinthaku.

Polimbana ndi thrombosis, fraxiparin ndiyabwino kwambiri. Kugwiritsa ntchito kumafotokozedwa mogwirizana ndi malangizo a mankhwalawa. Fraxiparin imalembedwa kwa odwala opaleshoni pakuchita opaleshoni kuti muchepetse thrombosis. Odwala omwe ali ndi purulent-septic, omwe ali ndi kupuma kapena mtima wosalephera amatenga kuti ateteze thromboembolism. Pazifukwa zomwezi, amalembera odwala hemodialysis.

Migwirizano yamagwiritsidwe

Tiona kuti ndi liti. Malangizo a mankhwalawa akusonyeza kuti mlingo uyenera kusankhidwa malinga ndi kulemera kwa wodwalayo. Komanso, chifukwa choikidwiratu chimakhudza kuchuluka ndi kuchuluka kwa makonzedwe. Malangizowo akunena kuti mankhwalawa amatha kubayira kamodzi kokha. Intramuscular and intravenous a mankhwalawa samaloledwa.

Ndikofunika kupaka jakisoni wa mankhwala pamalo a supine. Pangani jakisoni m'mimba. Fraxiparin imalowetsedwa mu khoma lachiberekero kapena khoma lam'mimba mwake, kuchokera kumanzere ndi mbali zamanja. Singano imayikidwa, ndikuyambitsa mankhwala, mosamalitsa, molunjika pakhungu, lomwe limayenera kusokonekera pakati pamlo ndi chala. Khola liyenera kuchitika osati panthawi yomwe singano yayikiridwa, koma mpaka kumapeto kwa mankhwala athunthu.

Sitikulimbikitsidwa kuphatikiza kayendedwe ka fraxiparin ndi potaziyamu ochepera okodzetsa, NSAIDs, ACE inhibitors. Samalembedwanso panthawi yomweyo ndi vikasol.

Zamkatimu:

Popeza ichi ndi mankhwala amphamvu, kugwiritsa ntchito kwake kumatheka pokhapokha ngati akuwuzani dokotala.

Mankhwala amatanthauza mankhwala okhala ndi anticoagulant kanthu. Chida ichi chimalepheretsa kuwonekera kwa magazi owundana, chifukwa chake nthawi zambiri chimagwiritsidwa ntchito pochiza komanso kupewa thrombosis yamitsempha yosakhazikika komanso yakuya kwambiri.

Komanso mankhwalawa amagwiritsidwa ntchito mochizira matenda ena owopsa a mtima.

Contraindication

Fraxiparin imaphatikizidwa chifukwa cha thrombocytopenia, magazi amawonjezereka, ndikugawa intravascular coagulation syndrome. Siyenera kulembedwa kwa anthu omwe ali ndi matenda a hemorrhagic, izi zimapangitsa kuti gawo lawonongeke. Odwala omwe ali ndi matenda oopsa komanso orthostatic hypotension sayenera kumwa mankhwalawa.

Iwo ali osavomerezeka kwa anthu omwe ali ndi kukokoka kwa zilonda zam'mimba kapena duodenum, magazi amatha. Ngati mukuwona mlingo wa mankhwalawa, ndiye kuti ndi wothandiza kwambiri polimbana ndi thrombosis. Ngati mulingo wambiri, magazi ochokera kwina atha kutuluka. Nthawi zina, thrombocytopenia imayamba.

Talongosola za mankhwalawa. Mupezanso zina zambiri zokhudza Faraskapin zothandiza, momwe mungadulire, muyenera kuonera kanemayo. Popeza jakisoni aliyense amafunikira chisamaliro komanso njira yosakhazikika.

Tulutsani mawonekedwe ndi zida zake

Mankhwalawa amapangidwa ngati njira yothetsera vutoli, kapangidwe kake kopanda utoto kapena kuwala kwake. Njira yothetsera vutoli imayikidwa mu ma syringes. Mankhwalawa adapangira jakisoni pansi pa khungu.

Ma syringe ndi yankho amayikidwa m'matumba. Chithuza chimodzi chimatha kukhala ndi syringe imodzi, ziwiri kapena zisanu, zomwe zimayikidwa m'matumba a makatoni.

Fraxiparin ili ndi zinthu zotsatirazi:

1. Chofunika kwambiri ndi calcium nadroparin. Mlingo wake ukhoza kukhala motere - 2850, 3800, 5700, 7600, 9500 IU anti-Xa.
2. Zowonjezera - hydrochloric acid, calcium hydroxide solution, madzi a jakisoni.

Mankhwala

Fraxiparin ndi membala wa gulu la anticoagulant lomwe limapangitsa antithrombotic kanthu. Calcium nadroparin ndi heparin yotsika kwambiri yochokera kwa heparin. Ngati tilingalira za mankhwala kuchokera kumbali ya mankhwala, ndiye kuti ndi glycosaminoglyan, yemwe kulemera kwake kwamphamvu ndi 4300 daltons.

Izi zawonjezera tropism ya protein protein antithrombin 3, zomwe zimapangitsa kutsika kwa factor Xa. Izi zimapangitsa kuopsa kwa antithrombotic mphamvu ya nadroparin.

Mfundo zina zowonjezera ntchito ya antithrombotic zimakhala ndi zolimbikitsa chinthu china cholepheretsa, kupititsa patsogolo microsolysis chifukwa cha kutulutsidwa mwachindunji kwa plasma plasmogenic activator kuchokera ku maselo a endothelial, komanso kusintha kusintha kwa hemorheological - kutsitsa kuchuluka kwa mawonekedwe a magazi, kuwonjezera kuchuluka kwa mapulateleti.

Poyerekeza ndi heparin wa mtundu wosasakanizidwa, umakhala ndi zotsika kwambiri pa zochitika zamagulu, pamapangidwe ophatikizika ndi boma la proostasis ya pulayimale.

Pa chithandizo ndi ntchito yayikulu, kuwonjezeka kwa APTT ndi 1.4 nthawi zazikulu kuposa momwe muyezo ungawonedwere. Ngati imagwiritsidwa ntchito mu prophylactic waukulu, ndiye kuti palibe kuchepa kwamphamvu kwa APTT.

Pa kuphatikiza mankhwala ndi subcutaneous jakisoni, pazenera ambiri mu magazi zimatheka mwa 4-5 maola. Mafuta aimpso amapezeka mpaka 88%. Pa intravenous makonzedwe, apamwamba ndende amawonedwa pambuyo 10 Mphindi.

Kuchotsa theka-moyo pafupifupi 2 maola. Mettabolization ya mankhwalawa imawonedwa kwambiri m'chiwindi ndi njira yowonongera kapena depolymerization.

Kodi zikuwonetsa chiyani?

Fraxiparin anagwiritsa ntchito matenda otsatirawa:

• popewa matenda a thromboembolic chikhalidwe, munthawi yochita opaleshoni ndi mafupa, pamaso pochulukira cha kuchuluka kwa magazi ku ICU mikhalidwe, yomwe imayendera limodzi ndi kupweteka kwambiri kapena kupuma kapena mtima.
• pachiwopsezo cha pulmonary embolism,
• kuthetsa zizindikiro za thromboembolic,
• Ndi prophylactic mankhwala a magazi pakupanga pa hemodialysis njira,
• kuthetsa kusakhazikika kwa angina ndi myocardial infarction popanda Q wave.

Momwe mungabayitsire Fraxiparin - malamulo, malingaliro, Mlingo

Njira yothetsera vutoli imalowetsedwa pakhungu. Ndi kuyambitsa kwa wodwala ayenera kunama. Mankhwalawa amayenera kupakidwa pakhungu pakhungu la anterolateral kapena posterolateral. Mankhwala amaperekedwa mbali iliyonse mbali - woyamba kumanja, kenako kumanzere. Mutha kuyambanso ntchafu.

Singano imayikidwa pansi pa khungu m'malo a perpendicular, koma osati ngodya. Asanakhazikitsidwe, khungu limayenera kumanikizidwa pang'ono. Amapangidwa pakatipa pakati pa chala chachikulu. Mafutawo amayenera kusungidwa pofika jakisoni wa mankhwala. Pambuyo pa jekeseni, malo omwe mankhwalawo adathandizira safunikira kuti azikupaka.

Zomwe mungagwiritse ntchito Nadroparin, kutengera zolinga:

1. Pa mankhwala a thromboembolism, ndipo atangomaliza kuchitira opaleshoni, tikulimbikitsidwa kupereka yankho la Fraxiparin muyezo wa 0,3 ml kapena 2850 IU anti-Xa, umachitika ndi jekeseni wa subcutaneous. Mankhwalawa amapaka jekeseni kwa maola awiri musanachitike opaleshoni ndipo kamodzi pa maola 24 aliwonse. Kuchiza sikuyenera kupitilira sabata, ndipo kutha kuchitika mpaka chiwopsezo cha kuundana kwa magazi kudutsa.
2. Munthawi ya prophylactic mankhwala a thromboembolism panthawi yamankhwala othandizira mafupa, jekeseni imapangidwa ndi jekeseni wa subcutaneous mu Mlingo wokhazikitsidwa ndi kulemera kwathunthu kwa thupi, pa kilogalamu imodzi ya kulemera kwa wodwalayo, mlingo wofikira 38 IU anti-Xa umafunika. Patsiku la 4 atachitidwa opaleshoni, mlingo ungathe kuwonjezeka mpaka 50%. Jekeseni woyamba wa mankhwalawa ayenera kuchitika maola 12 asanafike opaleshoni ndipo mlingo wachiwiri umachitika patatha maola 12 opereshoni itachitika. Zitachitika izi, jakisoni wa mankhwalawa amaperekedwa nthawi yonse yotsatila, mpaka chiwopsezo cha magazi amachepa, ndipo wodwalayo amamuthandizira kuti apite kuchipatala. Kutalika kochepa kwa njira za jakisoni kuyenera kukhala masiku 10.
3. Odwala omwe ali pachiwopsezo cha kuundana kwa magazi, limodzi ndi zotupa zam'mapapo, komanso kupuma kapena kulephera kwa mtima, mankhwalawa amaperekedwa kamodzi pa maola 24, amayenera kuperekedwa pakhungu. Mlingo wothetsera vutoli umakhazikitsidwa kutengera kulemera kwa thupi. Mankhwalawa amaperekedwa nthawi yonse ya chiwopsezo cha thrombosis.
4. Mankhwalawa a thromboembolism, mankhwala a anticoagulant ayenera kuthandizidwa atangoyamba kumene chizindikiro. Jakisoni wa Fraxiparin amachitika mpaka nthawi ya prothrombin yofunika itafika. Mankhwalawa amaperekedwa kawiri kawiri m'masiku 24. Kuvulala kumachitika maola 12 aliwonse. Mlingo wa yankho umatengera kulemera kwa thupi - 86 IU anti-Xa iyenera kuperekedwa pa 1 kg.

Kanemayo akuwonetsa momwe kudzipangira pawokha jakisoni wa Clexane, jakisoni wa Fraxiparin amachitidwira chimodzimodzi:

Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere

Malinga ndi kuyesa kwa nyama, pali umboni wochepa wosonyeza kuti zigawo za Fraxiparin zimadutsana ndi mwana, chifukwa chake kugwiritsa ntchito mankhwalawa panthawi yovomerezeka sikulimbikitsidwa, koma imagwiritsidwa ntchito pochita.

Nthawi zina pamakhala zosankha zina pomwe phindu kwa mayiyo limapitilira chiwopsezo kwa mwana.

Mukamayamwitsa, kugwiritsa ntchito mankhwalawa sikulimbikitsidwa, popeza zigawo zomwe zimapezeka zimatha kulowa mkaka.

Zotsatira zoyipa

Pogwiritsa ntchito mankhwalawa, zotsatirazi zingachitike:

• magazi amitundu ingapo,
• boma la thrombocytopenia ndi eosinophilia,
• kuchuluka michere chiwindi,
• Hypersensitivity zimachitika,
• hematomas imatha kuwoneka malo a jekeseni, mapangidwe olimba omwe amasowa mkati mwa masiku ochepa, nthawi zina necrosis imayamba, pomwe mankhwalawa amasiya.
• Hyperkalemia ndi priapism sizimawonekanso kawirikawiri.

Allergy to Fraxiparin jekeseni

Zochitika zofunikira ndizofunikira

Lingaliro la madokotala aluso ndi kuwunikira kwa anthu wamba za mankhwala a Fraxiparin.

Fraxiparin ndi chida chothandiza popewa komanso kuchiza matenda osiyanasiyana a thrombotic. Mankhwalawa amathandiza pafupifupi kuyambira koyamba kugwiritsa ntchito, zimachitika chifukwa cha zomwe ali nazo. Gawo lolimbikira limamangiriza mwachangu mapuloteni a plasma ndipo chifukwa chake limapanga antithrombotic.

Mankhwalawa, magazi amawundana ndipo magazi amawundana mwachangu. Chidacho chimachepetsa kukhuthala kwa magazi ndikuwonjezera kupezeka kwa ziwalo za mmagazi. Koma pakugwiritsa ntchito, ndikofunikira kuyang'anira momwe magazi alili, nthawi zina magazi amatha kutuluka.

Nthawi zambiri ndimapatsa Nadroparin kwa odwala anga kupewa ndi kuchiza matenda osiyanasiyana a thrombotic. Mankhwalawa amathandizira kuthetsa thrombosis, amachitira thromboembolism.

Kuphatikiza apo, kunena kuti, Fraxiparin ikhoza kugwiritsidwa ntchito pa nthawi yomwe mayi ali ndi pakati, mankhwalawa alibe zotsatira zoyipa kwa mayi ndi mwana, ngakhale malangizo amakunena mosiyana.

Pakukonzekera, mankhwalawa amalowera m'magazi, amachotsa kutupa, kupweteka ndikuchotsa zovuta zonse zomwe zimabweretsa matendawa. Koma musaiwale za zoyipa, chifukwa munthawi yogwiritsa ntchito mankhwalawa, muyenera kuyang'anira momwe thupi lanu lilili.

Ndisanatenge pathupi, ndinayezetsa zomwe zidandiwonetsa kuti ndili ndi magazi okwanira, monga adotolo adandifotokozera pambuyo pake, magazi akhungu amatha kuyambitsa matenda a thrombosis. Ndipo kuwopsa kwa magazi pa nthawi ya pakati kumakhala koopsa kwa mayi ndi mwana.

Adalamula Fraxiparin. Poyamba, sizinkawoneka bwino kuti ndimapereka jakisoni m'mimba mwanga, koma m'kupita kwa nthawi ndinazolowera. Poyamba, hematomas adapangidwa pamalo opangira jakisoni, koma kenako adadutsa. Ndinailowetsa jakisoni kwa milungu iwiri, pambuyo pake mayeso adakhala abwino.

Popeza ndili ndi moyo wobadwa ndi ana, kubereka mwana ndi chiyeso chonse kwa ine. Matendawa pazaka 7 zapitazi akhala cholepheretsa kuti ndikhale ndi mwana yemwe ndimamuyembekezera kwa nthawi yayitali. Nditatenga pakati, ndinapita kwa dotolo nthawi yomweyo, adandiuza kuti ndipatse jakisoni wa Fraxiparin nthawi yonseyi. Mankhwalawa amapangidwira kuti achepetse magazi komanso kupewa magazi ndi kuundana. Nthawi yomweyo ndidavomera. Ndidadzipangira jakisoni ndekha.

Mankhwalawa alibe zoyipa kwa mwana. Ndidachotsa mimba yanga modekha ndikubereka mwana wathanzi!

Kugula kwa mankhwalawo ndi mitundu yake

Mtengo wa mankhwalawo ndiwokwera kwambiri phukusi lokhala ndi ma syringe 0,3 kuchokera ku 2200 ndipo limafika ma ruble 4020, pa paketi ya Fraxiparin No. 10 0,6 ml - kuchokera 3400 mpaka 5000 rubles, analogies yotsatirayi yamankhwala imapezekanso kuti mugule:

Thandizani ndi matenda amitsempha.

Kukopera kwazovomerezeka ndizovomerezeka ndikungowonetsera komwe kukuchokera.

Chitani nafe ndipo tsatirani nkhaniyo pamasamba ochezera.

Ndemanga

Mwamuna wanga wandibaya, umanditenga m'mimba ndikuona mbali yakumanja)) sindinathe kudzipweteka)) poyamba sizabwino, kenako umazolowera! .. osadandaula)))

Palibenso chifukwa chochitira. Ndiwosavuta m'mimba mwanga, ngakhale sindinadule pakanthawi kanu, m'mbuyomu, pomwe kunalibe mimba iliyonse. Ndinkatola khungu ndikulowetsa singano (nthawi zina sikunali koyamba, manja anga akugwedezeka)) molunjika. Chachikulu ndikuti muzibayira jekeseni .. Nthawi zina zachitika kwa ine, ndimabaya m'mimba mwanga wonse, dzanja langa limanjenjemera, ndimanjenjemera (Kenako, ndikumachotsa singano, ndimayambitsa kunenepa. Mikwingwirima yake ndiyofunika .. Mudzaganiza ndikuyesa!)

Fungo langa lakumanzere limaluka ndikulowa m'mimba mwanga, pali mtundu wina wa singano wakuda. Mwamuna wanga adamuthira mankhwala a insulin ndikulowetsa insulin m'mimba mwake, monga jakisoni wina

Ndikukutumizirani ulalo mu PM ku maphunziro anga a kanema! Chilichonse ndichopepuka pamenepo!

Ndikuyitana pansi pa msomali. pa ngodya. osawopa konse. ingopendekerani ndi kulowa modekha. kulowa m'mimba, osati pansi pa khungu.

Zachilendo, adotolo adandiuza kuti si m'derali pafupi ndi msomali, ndikuchotsedwa ..

Sindili pansi pa msomali koma pansi pake.

Sindinadzibise: Ndinapita kuchipatala kwa masiku 10 kwa namwino

Onaninso

Atsikana ndiuzeni momwe ndingabayireko fraksiparin? M'mimba? Kuchokera pamalo opumira, malo omwe jakisoni imapwetekera ndikuvulala kotere, ndiye chifukwa chake tsiku lililonse kumavulala? Mimba yake idzakhala yakuda pamwezi. Zoyenera kuchita Ndiye ziyenera kukhala? Mayi, owopsa A.

Moni atsikana onse! Kolya fraksiparin m'mawa 0,3, madzulo 0,6. Zipatso zayamba kale kuwonekera. Singano siyofanana ndi yopyapyala. Ndiuzeni momwe mumabayira fraksiparin, mwina ndikupanga cholakwika, adandiuza kuti ndidabayitsa.

Moni atsikana! Adayikira fraksiparin 0,3 kuti alowetse, malangizo ndi YouTube akunena kuti muyenera kukoka khungu, ndipo adotolo adandigwira dzulo, osakoka, atangoyang'ana pakona, adayambitsa singano ndikuyika jakisoni. Mumadzitcha kuti fraks? Vulani khungu pakati pa zala zanu kapena.

Atsikana, ndili ndi moyo wobadwanso m'mimba ndipo ndinayankhidwa kuti ndipange jekeseni ya fakisi! Choyamba adaluka m'mimba 1 nthawi patsiku !! (uku ndi kumayambiriro kwa mimba). Kenako dotolo adayang'ana m'mimba mwanga wovulazidwa ndikuwuza.

TW! Lero madzulo a mafunso mwanjira inayake yanindifikira. Popeza d-dimer, rfmk idachulukitsidwa, fibrinogen adayikidwa kuti apange jekeseni ya faktiri 0.4. Ndipo kotero madzulo adafika, ndinayesa kupereka jakisoni m'dera la navel, singano sinali mwanjira iliyonse.

Moni atsikana onse. Ndinagula ovitrel nthawi yokhayi, ili ndi ma CD ena ndipo malangizo akuti muyenera kuyikakamiza m'mimba mwanu :( kapena sindimamvetsetsa kuti 🙁 atsikana omwe adabayitsa ovitere.

Moni anyamata! SOS! Kuyambira lero, muyenera jekeseni wa fakisi. Zaka zitatu zapitazo adandipatsa majakisoni atatu, ndipo ndidawayika mufiriji! Kodi amawonongeka? Malangizo (pa intaneti) akuti kutentha sayenera kupitirira 30 digiri, ndipo osatero.

Moni nonse! Adandiuza kuti ndipange jekeseni FRAXIPARINE. Momwe ndimakankhira molondola, sindimvetsa. Mchombo kapena kulikonse pamimba, ngakhale kuchokera kumbali? Khungu limatha "kugwidwa" kokha kuchokera kumbali, komanso m'dera la navel.

Kwa miyezi itatu motsatizana ndakhala ndikupanga jakisoni wa Fraxiparin, tsiku lililonse, m'mimba mwanga ndimabuluu komanso hematomas. Amasanthula izi zisanachitike. Ine ndi mwamuna wanga tinaganiza zoyeserera tsiku lililonse, ndipo tsiku lina ndinapambana mayeso. kudikirira zotsatira.

Njira yothandizira makonzedwe a Fraxiparin - momwe angagwiritsidwire ntchito mankhwalawa molondola?

Kodi kubaya Fraxiparin? Funso limakonda kufunsa kwa omwe adawalembera. The pharmacological zotsatira za mankhwala anticoagulant ndi antithrombotic.

Zomwe zimagwira mmenemo ndi calcium nadroparin. Nthawi zina zimachitika kuti dokotala amafotokozera mayi mankhwalawa.

Makamaka panthawi yoyembekezera, Fraxiparin amalembedwa kuti ateteze magazi ambiri, omwe angayambitse magazi. Komanso, mankhwalawa angagwiritsidwe ntchito onse kupewa matenda ndikuwachiza.

Odwala ena amamwa mankhwalawa kwa miyezi isanu ndi inayi. Ndiye mankhwalawa ndi chiani, ndipo mungamulase bwanji molondola?

Ogwira ntchito zamagulu azachipatala amati mankhwalawa ndi otetezeka kwathunthu, chifukwa chake simungadandaule za kuvulaza thanzi. Odwala ena omwe amawatenga amawona kuti malangizo ake samakhala ndi chidziwitso chogwiritsa ntchito mankhwalawa panthawi yopaka bere.

Pakadali pano, palibe maphunziro omwe adachitika pankhaniyi. Akatswiri ambiri amati chifukwa chake ndi motere: bukuli lilibe deta yatsopano, popeza sanalembedwe zaka makumi atatu.

Yothetsera subcutaneous makonzedwe a Fraxiparin

Mankhwalawa amalembedwa pokhapokha pazochitika zikuluzikulu, pomwe pali zovuta zambiri. Mwachitsanzo, ngati simulowa mankhwalawa panthawi yake osagwirizana ndi anticoagulant wowonjezera magazi. Matenda olakwika kapena kufa kwa mwana wosabadwa sikuchotsedwa.

Pa mndandanda wa contraindication, kuchuluka kwa zilonda zam'mimba kapena zilonda zam'mimba, kusokonezeka kwakukulu kwa magazi m'maso, ndi matenda ena akhoza kuphatikizidwa. Ponena za njira yoyendetsera, yankho lomwe limafunsidwa limayendetsedwa mosadukiza.

Munthawi imeneyi, wodwalayo ayenera kukhala wofulumira.

Mankhwalawa ayenera kuyikidwa pansi pakhungu pamalo anterolateral kapena pambuyo pake pamimba.

Zimayambitsidwa mbali iliyonse: woyamba kumanja, kenako kulamanzere.

Ngati mukufuna, mutha kulowa m'dera la ntchafu. Singano imayikidwa pansi pa khungu m'malo a perpendicular, popanda vuto lililonse. Asanalowetsedwe, khungu limayenera kumanikizidwa pang'ono pang'ono.

Amapangidwa m'derali pakati pa chala chachikulu. Malo omwe khola liyenera kusungidwa munthawi yonse yoyendetsera mankhwala. Pambuyo pa jekeseni, malo omwe mankhwalawo adagwiritsidwira ntchito sayenera kuzembedwa.

Zomwe mungagwiritse ntchito Fraxiparin kutengera zolinga:

Kuchuluka kwa mankhwala kumatengera kulemera kwa thupi. Ndi kulemera kwa makilogalamu 50 kapena kuchepera, mlingo woyenera wa mankhwalawa ndi 0,5 ml. Ili ndiye kuchuluka komwe kumayendetsedwa maola 12 musanachite opareshoni ndi kuchuluka komweko pambuyo pake.

Koma mlingo womwe umafunikira jekeseni kamodzi patsiku masiku anayi pambuyo pa opaleshoni ndi 0,3 ml.

Ngati kulemera kwa thupi kumasiyana mkati mwa kilogalamu, ndiye kuti muyenera kulowa 0,3 ml ya mankhwalawa maola khumi ndi awiri musanachite opareshoni komanso panthawi ngati itatha. Kuyambira tsiku lachinayi atachitidwa opaleshoni, voliyumu imodzi ya jakisoni wamankhwala ndi 0.4 ml.

Malemu opitirira 70 makilogalamu, mlingo woyenera ndi 0,4 ml kwa theka la tsiku musanayambe kuchita opareshoni. Koma kuchuluka kwa Fraxiparin, komwe kumachitika kamodzi patsiku lachinayi atachitidwa opaleshoni, ndi 0,6 ml.

Njira yolowetsera Fraxiparin pamimba: malamulo

Ndikofunikira kudulira mankhwala m'mimba. Sitikulimbikitsidwa kupereka jakisoni mu navel komanso mkati mwa thunthu.

Komanso, musalowe m'malo omwe muli mabala, mabala ndi mabala. Chala chachikulu ndi chofukula chimafunikira kupanga khola, zomwe zimapangitsa kuti pakhale makona atatu. Pamwamba pake pakhale pakati pa zala zanu.

Pansi pa khola ili, jekesani mankhwalawa ngodya yoyenera. Palibenso chifukwa chokwanira kuti musiyane ndi khola pakumwa mankhwala. Izi zikuyenera kuchitika mukangochotsa syringe. Sitikulimbikitsidwa kupaka jakisoni jekeseni.

Kanema wothandiza

Malangizo a momwe mungabayire Fraxiparin ndi mankhwala ena m'mimba, mu kanema:

Tiyenera kudziwa kuti mawonekedwe a edema yaying'ono pamalo opangira jakisoni amawonedwa ngati abwinobwino. Zachidziwikire, palibe chifukwa chodera nkhawa pokhapokha ngati izi sizikwiyitsa mkazi. Chofunikira: ndizoletsedwa kudzibaya ndi Fraxiparin popanda chilolezo cha dokotala, makamaka panthawi yapakati. Dokotala yekha ndi amene ali woyenera kumuyimira.

• Amachotsa zoyambitsa zovuta
• Imachepetsa kupanikizika mkati mwa mphindi 10 pambuyo pa kutsata

Momwe mungabayitsire fraxiparin?

Mwambiri, adandisankha motere: kuyambira 5 dts mpaka kumayambiriro kwa tsiku la M.

muyenera kubaya tsiku lililonse nthawi yomweyo, kuyambira tsiku loyamba osatulutsa mpaka chiyambi cha kusamba

Ndikungowonjezera kuti muyenera kutola khola, kumudula, kutulutsa singano, ndikungotulutsa khola.

musaope kuyika singano njira yonse - ndi yaying'ono, ngakhale atsikana onenepa kwambiri m'malo ano amakhala ndi mafuta owonda kwambiri

Osaloleza kutuluka, ndiye kuti! Pambuyo poti singano yachotsedwa pomwe amatha kutulutsidwa.

Malonda Otchuka a Blog

Ndizodabwitsa kuti chiwerengero chocheperako cha azimayi chimapanga phokoso lalikulu chotere.

Sindinakhale pano kwa nthawi yayitali. Ponena za ana - zonse sizisintha. Sichoncho, palibe mimbayo ngakhale. Koma.

Nthawi yoyamba yomwe ndidabwera ku ndege ya mwana kudzalandira upangiri pa magawo a BT. Njira ikuyenda, ndipo tsopano ndikudziwa kale.

Zithunzi zochititsa chidwi pagulu

Monga ambiri pano, ndikuyesera ndikudikirira X, koma ndikuyesera mayeso kale: (DPO, Evie. Nthawi.

Chonde onani, ndi 28 ma dts ndi 30 dts. Kodi pali zozizwitsa zina? Chowonadi ndi chakuti hcg siyabwino kwambiri.

Chifukwa chiyani ndikulowa DC, chifukwa Sindikudziwa ndendende nthawi yomwe oh anali, komanso pomwe kudabwitsidwako kunalinso. dongosolo.

Zolemba zabwino kwambiri mulaibulale

Pakati pa zaka zana zapitazi, katswiri wazokhudza zakugonana waku America komanso pulofesa wa matenda azachipembedzo a Arnold Kegel adayamba.

Kodi chotupa chamchiberekero chimayambitsa kusabereka? Mimba imachitika bwanji ndimatenda amtunduwu? O.

Kutsatira malamulo oyesa kutentha ndikofunikira kuti pakhale dongosolo lodalirika. Koma kumanga manda.

Kubwezeretsanso zinthu zapaintaneti ndizotheka pokhapokha ndi cholumikizira mwachindunji ku www.babyplan.ru

Kugwiritsa ntchito ma anticoagulants pamimba: Fraxiparin

Pa nthawi ya pakati, pamakhala nthawi zina pamene dokotala, atayesedwa magazi motsatira, amapatsa mkazi mankhwala owonjezera - anticoagulant. Chizolowezi chopanga magazi kuundana nchowopsa m'moyo wa mayi ndi mwana, chifukwa chake ndizololeka kugwiritsa ntchito mankhwala omwe akuphwanya panthawiyi. Fraxiparin pa nthawi yoyembekezera, ngakhale kuti malamulo oletsedwa amaletsedwa, amapatsidwa njira yoletsa hypercoagulation. Akatswiri ambiri azachipatala amavomereza kuti mankhwalawa, ngati agwiritsidwa ntchito moyenera, samavulaza mwana wosabadwayo.

Limagwirira zake Fraxiparin

Fraxiparin ndi heparin yotsika kwambiri yomwe imakhala ndi anticoagulant. Mwanjira ina, zimalepheretsa kutseguka kwa tinthu timene timayambitsa kukokoloka kwa magazi. Ndi kuperekera mankhwala pafupipafupi, magazi amawaletsa.

Chithandizo chophatikizika cha Fraxiparin ndi calcium nadroparin. Thupi limatha kupanga mwachangu komanso modalirika kupanga ma cell mamolekyulu a plasma. Ndi njira imeneyi yomwe imalepheretsa magazi kuwonekera. Kuyambika kwa Fraxiparin, kapena calcium nadroparin, kumakhudzanso mphamvu ya magazi ndipo nthawi yomweyo sizimayambitsa zovuta. Monga ma heparin onse, sizimawonjezera mwayi wokhetsa magazi.

Thrombophilia ndimatenda okhetsa magazi omwe ali pachiwopsezo cha kuundana kwa magazi. Vutoli limatha kubweretsa imfa ya fetal mkati mwa chiberekero. Fraxiparin pa nthawi yomwe mayi ali ndi pakati amakhala ndi magazi abwinobwino kwa mwana wosabadwa, sikuvulaza thanzi la mayi. Chinanso chophatikiza ndi mankhwalawa ndikuti sichidutsa muchotsekera komanso sichikhudza mwana wosabadwayo.

Gwiritsani ntchito pa nthawi yoyembekezera

Pa nthawi yoyembekezera, Fraxiparin amapatsidwa mankhwala ochizira omwe amakhudzana ndi kuchuluka kwa magazi, komanso chifukwa cha kupewa. Kutalika kwa maphunziro a mankhwalawa amasankhidwa payekha: nthawi zina, onse ndi miyezi 9. Chithandizo cha nthawi yayitali chitha kufunikira ngati m'mbuyomu mayi adasokonezeka chifukwa cha magazi. Zikatero, ngakhale kupumula kwa tsiku limodzi pakukonzekera kwa mankhwalawa kumatha kupha mwana wosabadwayo.

Ndizosatheka kunena ndendende momwe Fraxiparin imakhalira nthawi yapakati. Malangizowa ali ndi chidziwitso kuti kuikidwa kwake ndikotheka mu 2nd ndi 3 trimesters. Akatswiri a Hemostasi akutsimikiza kuti mankhwalawa alibe vuto kwa mayi ndi mwana wosabadwa, koma palibe kafukufuku wazachipatala wa gulu ili omwe adachitidwa. Ndiye kuti, funso la teratogenicity la Fraxiparin likadali lotseguka. Komabe, mankhwalawa agwiritsidwa ntchito kwa nthawi yayitali pochiza komanso kupewa kuchuluka kwa magazi azimayi apakati, ndipo zonena zakezi sizinasinthidwe kwazaka zambiri.

Fraxiparin woyembekezera amakhazikika. Atalandira chidziwitso chodziwitsa za Laborator, adotolo amawona kuopsa kwa kubadwa mwachangu ndi mwana wosabadwayo, kenako amasankha ngati angagwiritse ntchito mankhwalawa. Kuyendetsa kwake pafupipafupi kumathandizira kubwezeretsa magazi mwachizolowezi komanso kupewa zovuta zoterezi.

Trimester yoyamba ndiyoopsa kwambiri kumwa mankhwala aliwonse, kuphatikizapo anticoagulants. Amayesa kuchedwetsa kugwiritsa ntchito mpaka milungu 16, pamene placenta ipangidwe. Mu 2nd ndi 3 trimesters, ndizovomerezeka kugwiritsa ntchito ngati mayi wapakati alibe zotsutsana zina.

Nthawi yayitali, amakhala pachiwopsezo cha kusokonezeka chifukwa cha kuchuluka kwa magazi. Placenta imakula m'miyezi yonse 9; kuchuluka kwa zombo zazikulu ndi zazing'ono kumakhala kukuchulukirachulukira. Thrombi amapanga msanga kwambiri ma capillaries, zomwe zimabweretsa kudwala kwa fetal hypoxia ndikuchedwa kuchedwa kwa fetal.

Mu trimester ya 3, chiberekero ndi mwana wosabadwayo amafika pazokulira zawo. Mokulira akamakulirakulira, pomwe amachepetsa misempha yonyansa, pomwe magazi amayenda kuchokera ku miyendo mpaka pamtima. Zotsatira zake, zimayenda, zomwe zimatsogolera pakukula kwa magazi. Njira yowopsa kwambiri ndiyo kuphwanya kwam'mitsempha yam'mimba, izi zimatha kupangitsa kuti mayi wapakati aphedwe.

Zikuwonekeratu kuti pali zofunikira pakuwonetsa Fraxiparin. Muzochitika zonse zomwe tafotokozazi, zoopsa zomwe zimagwiritsidwa ntchito ndizochepa kuposa zotsatira za kuphwanya magazi.

Mukakonzekera kukhala ndi pakati, fungo la fakisoni limapangidwanso kuti magazi azitha kuchuluka.Thrombosis ndi chimodzi mwazifukwa zomwe zimalepheretsa kukhazikitsidwa kwa dzira lakumana ndi khoma la chiberekero. Ndiye kuti, kuyambitsa kwa mankhwalawa kumathandizira kutenga pakati.

Njira yogwiritsira ntchito

Mukamapereka mankhwala a Fraxiparin pa nthawi yomwe muli ndi pakati, ndikofunikira kudziwa momwe mungamudulire. Wopanga amakhala ndi nkhawa za kugwiritsidwa ntchito mosavuta: mankhwalawa amapezeka mu mawonekedwe a yankho lomwe limatsanulidwa mu syringes zotayidwa ndi singano yothandizidwa pansi pa khungu. Kuchuluka kwa mlingo umodzi kungakhale kosiyana, m'mafakitala mungapeze zosankha: 0.3 ml, 0.4 ml, 0.6 ml, 0.8 ml, 1 ml.

Pakati pa nthawi yayitali, mlingo woyenera nthawi zambiri umafotokozedwa - 0,3 ml, 1 nthawi patsiku. Kutalika kwa nthawi ya jakisoni kumasankhidwa payekha, koma sikungakhale kosakwana masiku 10. Mlingo umachulukitsa ngati mzimayi ali ndi thupi lalikulu.

Njira yoyenera mukakhazikitsa Fraxiparin ikuchitika ndi katswiri wazachipatala. Koma popeza ambiri amamwa mankhwalawa kwa nthawi yayitali, ndipo nthawi zina kwa miyezi 9 yonse, zimafunikira kuti mudziwe nokha njira imeneyi. Ndipo komabe, musanasinthe kupita ku chithandizo chanyumba, ndikofunikira kuti katswiri azichulukitsa jakisoni zingapo. Chifukwa chake zitha kuwona njira yoyenera ndikumvetsetsa zomwe zomverera zingakhale nawo poyambitsa yankho.

Kuyamba kwa yankho ndi motere:

1. Chotsani mpweya mu syringe pochisinthira ndi singano.

2. Konzani ubweya wa thonje wothira kumowa.

3. Bodza pa nsana wanu ndikuthira malo ochepa a khungu ndi mowa, ndikubwerera kuchokera ku navel masentimita pang'ono.

4. Pamalo ogwiridwayo, gwiritsani khungu lanu ndi zala ziwiri.

5. Pamwamba pa khola, ikani singano pamalo a 90 ° mpaka khungu lonse.

6. Imbirani piston pang'onopang'ono mpaka njira yonse itayambitsidwa.

7. Chotsani singano, kanikizani ubweya wa thonje kupita kumalo opumira.

Pambuyo pa njirayi, kupukuta malo a jakisoni sikuyenera kuloledwa. Tsiku lililonse muyenera kusintha, kusinthana mbali (kumanzere, kumanja). Mukangochotsa singano, magazi ochepa amatha kuwoneka pamalo opumira, ndipo patapita kanthawi - kutupa pang'ono. Izi ndizabwinobwino ndipo siziyenera kuchita mantha.

Fraxiparin pa nthawi yapakati imatha kupezeka kwaulere. Chotsitsa cha mankhwalawa chimachitika kuchipatala cha anakubala komwe amakhala. Risiti yake imaperekedwa kudzera mwa satifiketi yobadwa mu dongosolo la dziko "Health" (Order of the Ministry of Health and Social Development of the Russian Federation of Januari 16, 2008 N 11Н).

Zotsatira zoyipa ndi zotsatira zake

Zotsatira zoyipa zoyendetsedwa ndi Fraxiparin nthawi zina zimawoneka ngati zimachitika pakhungu: tsamba la jakisoni limayamwa ndikuphimbidwa ndi zotupa. Zoletsa zimatha kudziwonetsa mu urticaria, edema ya Quincke. Kugwedeza kwa anaphylactic ndikosowa kwambiri. Ngati mankhwala osokoneza bongo, magazi amatha kutuluka.

Fraxiparin pa nthawi ya pakati imalembedwa nthawi zonse pamaziko a zisonyezo zazikulu, zotsatira za mwana wosabadwa sizinaphunzire. Koma madotolo ambiri amavomereza kuti ngati mlingo umayang'aniridwa, ndiye kuti chiwopsezo chakupezeka kwawo sichochepa.

Pharmacodynamics ndi pharmacokinetics

Helo wochepa kwambiri wa heparin wopangidwa ndi depolymerization kuchokera ku heparin yodziwika bwino kwambiri ndi glycosaminoglycan wokhala ndi maselo olemera pafupifupi 4300 daltons.

Amakhala ndi kutentha kwa magazi mapuloteni antithrombin 3, komwe kumabweretsa kuponderezedwa kwa chinthu Xa - izi zimachitika makamaka chifukwa cha mphamvu ya nadroparin.

Ntchito: minofu chinthu kusintha blocker, fibrinolysis yotulutsa mwachindunji minofu plasminogen zolimbikitsa kuchokera endothelial zimakhala, kusintha kwamitsempha yamagazi (kuchepa kwa mamasukidwe amwazi ndi kuwonjezeka kwa kuchuluka kwa kupatsidwa zinthu zam'magazi ndi granulocyte cell membranes.

Poyerekeza ndi heparin yopanda mafuta, imakhala yofooka kwambiri pantchito ya kupatsidwa zinthu za m'magazi, kuphatikiza, ndi hemostasis yoyamba.

Munthawi yamankhwala omwe mumalandira chithandizo chokwanira ndi ntchito yambiri, kuchuluka kwa APTT kwa nthawi 1.4 zomwe muyezo ndizotheka. Mlingo wa prophylactic, sizimapangitsa kuchepa kwamphamvu kwa APTT.

Pambuyo pa jekeseni wa subcutaneous, ntchito yapamwamba kwambiri ya anti-Xa, ndiye kuti, kuchuluka kwambiri m'magazi kumatha pambuyo pa maola 4-5, pafupifupi kutengeka kwathunthu (mpaka 88%). Ndi jakisoni wovomerezeka, ntchito yapamwamba kwambiri ya anti-Xa imachitika pakatha mphindi 10. Kuthetsa theka-moyo wafika 2 maola. Komabe, katundu wa anti-Xa amawonekera kwa maola osachepera 18.

Zimapukusidwa mu chiwindi mwa kuwonongedwa ndi kufalikira.

Malangizo ogwiritsira ntchito Fraxiparin (Njira ndi Mlingo)

Malangizo ogwiritsira ntchito akuwonetsa kuti mankhwalawa amayenera kuperekedwa pang'onopang'ono m'malo omwe ali pamimba, kusintha pakati pa mbali zamanzere zamanzere zam'mimba. Mutha kubayira mankhwala mu ntchafu.

Popewa kutayika kwa mankhwalawa, osayesa kuchotsa thovu mu mpweya ku syringe musanalowe.

Nthawi zambiri, funso limakhala m'magulu akuti "prick Fraxiparin?" Ndikofunikira kuyika singano perpendicularly khola la khungu lopangidwa ndi zala za manja aulere. Khola liyenera kuchitika nthawi yonse ya mankhwalawa. Malowo a jakisoni sayenera kutupikiridwa.

Vidiyo momwe mungabayere Fraxiparin

Kupewa thromboembolism mu opaleshoni, subcutaneous mlingo wa 0,3 ml wa Fraxiparin (2850 anti-Xa ME) tikulimbikitsidwa. Mankhwalawa amaperekedwa maola 4 asanayambe ntchito, pambuyo pake - kamodzi patsiku. Chithandizo cha mankhwalawa chimapitilizidwa kwa pafupifupi sabata limodzi kapena nthawi yonse ya chiwopsezo cha kuchuluka kwa magazi musanayambe kuwunika.

Pofuna kupewa thromboembolism panthawi ya mafupa, Fraxiparin imayendetsedwa mosalekeza pa 38 anti-XA IU pa kilogalamu imodzi ya kulemera, mlingo uwu ukhoza kuwonjezeka kamodzi ndi theka tsiku lachinayi atachitidwa opaleshoni. Mlingo woyamba umaperekedwa maola 12 musanachite opareshoni, wotsatira - nthawi yomweyo atachitidwa opaleshoni. Kuphatikiza apo, Fraxiparin imagwiritsidwa ntchito kamodzi patsiku nthawi yonse yokhala pachiwopsezo cha thrombosis wodwala asanalowe kuwunikira. Kutalika kwa mankhwala osachepera masiku 10.

Odwala omwe ali ndi chiopsezo chachikulu cha thrombosis (mwachitsanzo, m'malo ogona kwambiri kapena malo osamalira kwambiri, kupuma kapena kulephera kwa mtima), Fraxiparin imayendetsedwa kamodzi kamodzi patsiku pazambiri zomwe zimawerengeredwa kutengera kulemera kwa wodwala: 3800 anti-XA ME amathandizidwa ndi kulemera kosakwana 70 kg patsiku, ndipo ndimphamvu yoposa 70 kg, 5700 anti-Ha ME amaperekedwa tsiku lililonse. Chida chimagwiritsidwa ntchito nthawi yonse ya chiwopsezo cha thrombosis yowonjezereka.

Pochiza matenda a mtima popanda kukhalanso ndi mafunde a Q osakhazikika kapena angina osakhazikika, mankhwalawa amayikidwa pang'onopang'ono maola 12 aliwonse. Kutalika kwa chithandizo ndi masiku 6. Mlingo woyamba umatheka kamodzi kudzera mwa njira ya bolus, milingo yotsatirayi imayendetsedwa mosagwirizana. Zimakhazikitsidwa potengera thupi la wodwalayo - 86 anti-XA ME pa kilogalamu yolemera.

Mankhwala a thromboembolism, ma anticoagulants mapiritsi ayenera kuikidwa mofulumira. Chithandizo ndi Fraxiparin sichimayimitsidwa mpaka zolinga za nthawi ya prothrombin zitheke. Mankhwala wovomerezeka pang'onopang'ono maola 12 aliwonse, muyezo wa maphunzirowo ndi masiku 10. Mlingowo umaperekedwa pamlingo wa 85 anti-Ha IU pa kilogalamu imodzi ya kulemera.

Bongo

Chithandizo: Kuchepetsa magazi sikufunikira chithandizo (chotsitsa mlingo kapena chepetsani jakisoni wotsatira). Protamine sulphate limapangitsa anticoagulant zotsatira za heparin. Kugwiritsidwa ntchito ndikofunikira pokhapokha ngati pali milandu yayikulu. Muyenera kudziwa kuti 0,6 ml ya protamine sulfate neutralates pafupifupi 950 anti-Xa ME nadroparin.

Kuchita

Chiwopsezo cha hyperkalemia chikuchulukitsidwa chikaphatikizidwa ndi mchere wa potaziyamu, zoletsa za ACE, zoteteza potaziyamu, angiotensin receptor blockers, heparins, non-steroidal anti-kutupa mankhwala, tacrolimus, cyclosporin, trimethoprim.

Ntchito zophatikizika ndi acetylsalicylic acid, anticoagulants, NSAIDs, fibrinolytics kapena dextran onse pamodzi zimalimbikitsa zotsatira za mankhwalawo.

Malangizo apadera

Fraxiparin saloledwa kuperekedwa kudzera mwa intramuscularly.

Zilibe mphamvu pakuyendetsa.

Analogs of Fraxiparin: Atenative, Wessel Duet F, Heparin, Heparin-Biolek, Heparin-Darnitsa, Heparin-Indar, Heparin-Novofarm, Heparin-Farmeks, Kleksan, Novoparin, Flenoks, Fragmin, Zibor, Enoksarin.

Zaka mpaka 18 ndi kuphwanya kukhazikitsidwa kwa mankhwalawa.

Fraxiparin pa mimba (ndi mkaka wa m`mawere)

Kashiamu nadroparin amadutsa placenta panthawi yoyembekezera ndipo amachotseredwa mkaka wa m'mawere. Chifukwa chake, jakisoni wa Fraxiparin pa nthawi ya bere komanso panthawi yoyamwitsa salangizidwa kuti apereke mankhwala, kupatula ngati ali ovuta kwambiri.

Amasankhidwa kuti azisinthasintha magazi m'magazi, chifukwa kugwiritsa ntchito mahomoni kumayambitsa zosiyana, ndikuwongolera kulowetsedwa.

Ndemanga za Fraxiparin

Ndemanga za wodwala zamankhwala ndizosiyana, koma simuyenera kudalira iwo ngati mwalandira chithandizo ndi Fraxiparin. Kulungamitsa cholinga cha mankhwalawo, kugwira ntchito kwake komanso zoopsa zonse zomwe zimakhudzana ndi izi zitha kungoyesedwa ndi katswiri.

Palibe ndemanga zoyipa za Fraxiparin pa nthawi yoyembekezera kuchokera kwa omwe adalandira chithandizo. Kuchita kumawonetsa kuti mankhwalawa samakhudza thanzi la ana. Mu Chinsinsi cha Chilatini, dzina la malonda limamveka ngati Fraxiparini.

Mtengo wa Fraxiparin, komwe mugule

Ku Russia, mtengo wa Fraxiparin No. 10 0,3 ml ndi ma ruble (kugula ku Moscow kumawononga ndalama zofanana). Ku Ukraine, mtengo wa mankhwalawa mwanjira yotulutsidwa ndi 510 hryvnia. Mtengo wa analogi womwe umagwiritsidwanso ntchito pa nthawi yapakati umakhala wotsika kwambiri nthawi zonse.

• Mankhwala Ogulitsa Pa intaneti ku Russia
• Mankhwala apulogalamu apakompyuta Ukraine Ukraine

Mankhwala IFK

Maphunziro: Omaliza maphunziro ku Vitebsk State Medical University omwe ali ndi digiri ku Opaleshoni. Ku yunivesiteyo, adatsogolera Council of the Student Science Science Society. Maphunziro ena mu 2010 - mu "Oncology" apadera komanso mu 2011 - mu apadera "Mammology, mawonekedwe a oncology".

Zochitika pantchito: Gwirani ntchito kuchipatala kwazaka 3 ngati dokotala wa opaleshoni (Vitebsk emergency hospital, Liozno CRH) and onologistologist and traumatologist. Gwira ntchito ngati nthumwi yaulimi mzaka zonse ku Rubicon.

Adapereka malingaliro atatu omasulira pamutu wakuti "Kukhathamiritsa kwa mankhwala opha maantibayotiki kutengera mtundu wa microflora", 2 ntchito zidapeza mphotho mu republican mpikisano-wamaapepala owerengera ophunzira (magawo 1 ndi 3).

Tatiana: Ndimagwira ntchito ya gynecology. Milandu yambiri yoyipa idachitika chifukwa cha postinor, mpaka.

Leonid: Nkhani yabwino. Ndimagwiritsa ntchito zitsamba za Ayurvedic Brami Bati, Kapikachu kwa.

Victoria: Ndinali ndi ma comedones, kuwoneka kunali kosasangalatsa komanso koyipa. Masks, zopaka zimangokulitsa.

Victoria: Ndipulumutseni! Mwa NSAIDs zonse zomwe ndayesera kale, zimatha kulolera mosavuta ndipo inde.

Zipangizo zonse zomwe zimaperekedwa patsamba lino ndizachidziwitso komanso maphunziro okha ndipo sizingaganizidwe ngati njira ya chithandizo kapena kufunsira wokwanira kokhazikitsidwa ndi dokotala.

Oyang'anira tsamba ndi olemba nkhani sakhala ndi vuto pazotayika zilizonse komanso zomwe zingachitike mutagwiritsa ntchito malowa.

Mimba

Fraxiparin ndi heparin wochepa wamolekyu okhala ndi anticoagulant. Ma anticoagulants amatchedwa mankhwala omwe amasokoneza kutseguka kwa dongosolo lomwe limayendetsa magazi ndikupangitsa kuti magazi asachitike. Ngati pakati pa mimba pali zifukwa zabwino kwambiri, ndiye kuti Fraxiparin amalembedwa ndi dokotala.

Chomwe chimagwiritsa ntchito mankhwalawa ndi calcium nadroparin, yomwe imatha kumanga mwachangu komanso mwamphamvu kumapuloteni a plasma, omwe amathandiza kupewa mawonekedwe a magazi.

Pa nthawi yoyembekezera, Fraxiparin imatha kutumikiridwa pochiza matenda omwe amayamba chifukwa cha kuchuluka kwa magazi komanso kupewa. Nthawi zina, mzimayi amakakamizidwa kulandira mankhwalawa kwa miyezi isanu ndi inayi yobala mwana. Izi zimachitika nthawi zambiri pamene mkazi wataya mwana wake kale chifukwa cha kutaya magazi. Akatswiri a Hemostasi akuti ngakhale kugwiritsa ntchito mankhwalawa kwa nthawi yayitali sikukhudza mwana wosabadwa munjira iliyonse, ndipo kuyimitsa jakisoni ngakhale tsiku limodzi kumatha kubweretsa imfa ya mwana.

Madokotala ena amati mankhwalawa ndi amakono komanso alibe vuto pakubala kwa mwana wosabadwayo. Ena amakhulupirira kuti kusowa kwa kofutira kogwiritsa ntchito panthawi yomwe ali ndi pakati ndi chifukwa chakuti palibe kafukufuku yemwe wachitika pa zotsatira za teratogenic pa amayi apakati ndi ana awo. Enanso ali ndi lingaliro kuti Fraxiparin yakhala ikugwiritsidwa ntchito kwakanthawi, ndipo malangizowo sanakonzedwenso kwa zaka 30 ndipo ali ndi data yakale.

Fraxiparin nthawi zambiri samatchulidwa pakakhala pathupi pakafika vuto lalikulu lomwe limawopseza ndi zovuta monga kutaya pakati, kubadwa msanga kapena kufa kwa fetal. Kuchulukitsa kwa magazi kungakhale ndi zotulukapo.

Mu trimester yoyamba, amayesetsa kuti asapereke mankhwala ngati mungalandire chithandizo kapena kupewa. Mu trimesters yachiwiri ndi yachitatu, kugwiritsidwa ntchito kwake ndizotheka popanda contraindication.

Kufunika kwa Fraxiparin nthawi yobala mwana kumachitika chifukwa chakuti placenta imachulukirachulukira kukula kuposa miyezi isanu ndi inayi, mitsempha yamagazi ndi ma capillaries ambiri amawonekera mmenemo. Ndi kuchuluka kwa magazi m'magazi, kumatha kuyendayenda m'magulu ang'onoang'ono, kumathandizira magazi, zomwe zimapangitsa kuti mwana asadutse ndi mpweya wabwino.

Mu trimester yachitatu, mitsempha ya m'chiuno chaching'ono imalimba mwamphamvu ndi chiberekero chokulirapo, chifukwa chomwe chikuchepa pakukutulutsa kwa magazi kuchokera m'mitsempha yam'munsi. Zotsatira zake, magazi amayenda mkati mwake ndipo magazi amawundana. Chovuta kwambiri cha vutoli chimatha kukhala embolism, yomwe imatha kupha mkazi ndi mwana wosabadwa, motsatana.

Njira zogwiritsira ntchito

Mankhwala amatchulidwa ndi dokotala pokhapokha mayi woyembekezera atapenda kusanthula kwa magazi kuti awoneke ngati ali ndi magazi. Chithandizo chotsatira chiyenera kuyang'aniridwa mosamala ndi madokotala. Maphunzirowa ndi nthawi yayitali ya chithandizo cha mankhwala a Fraxiparin amaperekedwa.

Fraxiparin imapezeka mu ma syringes otayika ndi singano yopyapyala ya hypodermic, yokhala ndi yankho lomveka bwino la 0.3 mg mkati. Mankhwalawa amalowetsedwa m'dera pamwamba pa msomali. Mukamayambitsa yankho, ndikofunikira kugwira chikhodzodzo, ndipo singano iyenera kukhala yodutsa khungu.

Nthawi zambiri, jakisoni wa Fraxiparin amathandizidwa ndi odwala ndipo samayambitsa mavuto, monga nseru ndi ululu. Nthawi zambiri pamakhala kumverera kowotcha pamalo a jakisoni, koma pofuna kupulumutsa moyo wa mwana, izi zitha kupirira. Ngati mayi akukakamizidwa kulandira chithandizo chamanthawi yayitali, ndiye kuti mwina sangayendere kuchipinda chamankhwala tsiku lililonse, koma angonena jakisoni payekha kapena mothandizidwa ndi okondedwa.

Kuphika kwa Fraxiparin mu Mimba mwa Amayi Oyembekezera

Kukhazikitsidwa kwa yankho la Fraxiparin mwa amayi apakati ndi koyenera kuti mupeze zovuta zamachitidwe osokoneza. Mukanyamula mwana, chiopsezo cha kuwundana kwa magazi kwa mayi m'tsogolo chifukwa cha kukula kwa placenta, omwe zigawo zake zili m'mitsempha yamagazi. Pamaso pa zinthu zomwe zimayambitsa vuto, kukhalanso kwa thrombosis, komwe kumayambitsa kupindika kwa magazi, kuperewera kwa michere kumawonjezeka.

Kuperewera kwa okosijeni ndi michere ina ndikuyambitsa kuwonongeka kosasintha kwa mthupi la mluza pamaselo a ma cell, chifukwa chake, kuti athetse chiwopsezo ku thanzi la mayi wapakati, komanso pakukula kwachilendo kwa mwana wosabadwayo, heparin glycosaminoglycan akuyenera.

Limagwirira zake ntchito mankhwala

Njira yothetsera Fraxiparin poika makina osunthika ndi heparin yotsika kwambiri (yolemetsa ya glycosaminoglycan heparin), yomwe ili ndi tanthauzo la antithrombotic. Mankhwala imayambitsa zinthu coagulation, ali ndi antiplatelet kwenikweni, ndipo samalimbitsa mphamvu yogwira mbali ya thromboplastin nthawi.

Mndandanda wazowonetsa ndi zotsutsana

Jekeseni wa Fraxiparin m'mimba kuti muchepetse magazi amagwiritsidwa ntchito pofuna kupewa komanso kuchiza magazi omwe akuwonjezeka kapena matenda omwe amapangidwa kale. Kuphatikiza pa kugwiritsidwa ntchito pakubala, mankhwalawa amagwiritsidwa ntchito pochiza mitsempha yakuya, komanso kupanga hemophilia yochita kupanga pakukhudza mtima.

Milandu ikuluikulu yoyendetsera Fraxiparin ndi:

• kusalolera payekhapayekha,
• bakiteriya pachimake pakatikati mwa mtima,
• kutupa kwa serous nembanemba wamtima (pericarditis),
• thrombocytopenia ndi wabwino mayeso kuphatikiza in vitro ndi kuwonjezera kwa mankhwala,
• hemorrhoidal stroke,
• immunopathological mtima kutupa,
• chachikulu serous chorioretinopathy,
• matenda oopsa komanso hypotension ya postural.

Mosamala, Fraxiparin imalembedwa kwa odwala omwe akutulutsa magazi, kuvulala kwamitsempha yama neva, kupweteka kwambiri kwa hepatic kapena aimpso, matenda a shuga, komanso kuchulukitsa kwa zilonda zam'mimba.

Mlingo ndi njira yoyenera ya makonzedwe

Fraxiparin imapezeka mu syringes isanadzazidwe ndi yankho la subcutaneous makonzedwe, zidutswa 10 paphukusi lililonse. Mlingo umodzi umasiyana kuchokera pa 0,3 mpaka 1 ml. Musanalandire chithandizo, dziwani kuchuluka kwa maselo odyera m'magazi, ndiye kuti 2 pa sabata pa nthawi ya mankhwala, yang'anirani mulingo wawo.

Pofuna kupewa thromboembolism pa nthawi yobereka, mlingo wochepa wa 0.3 ml umayikidwa kamodzi patsiku.

Pamaso pa opareshoni, mankhwalawa amaperekedwa kamodzi maola ochepa asanachitidwe opareshoni. Njira ya jakisoni imapitilizidwa kwa sabata pambuyo pakuchita opaleshoni mpaka wodwalayo atachira.

Fraxiparin imachotsa bwino mankhwala a heparin thrombosis. Mankhwala chikuyendetsedwera ndi maola 12 kwa masiku 10. Mlingo wa mankhwalawa umatengera kulemera kwa wodwala.

Malonjezo Amisili Yoyambira

Kuti tikwaniritse zotsatira zofunika, ndikofunikira kupaka jekeseni wa Fraxiparin m'mimba nthawi yapakati. Mukafuna kudziwa jekeseni, malo a navel amapewedwa, komanso gawo lamatumbo, malo oyenera ndi gawo lotsatira khoma lam'mimba. Popewa kupanga zisindikizo kapena mabampu, sikulimbikitsidwa kuyendetsa mankhwalawa ngati pali edema, zipsera, zipsera pamimba, kuphwanya umphumphu wa khungu, matenda amkati kapena matupi awo.

Jakisoni amapangidwa mu tinthu ting'onoting'ono mpaka pansi pafupi mamilimita 15, atachiritsa khungu ndi antiseptic. Kutsogolo ndi zala zakumanzere zimagwira gawo la khungu lam'mimba kuti lipange. Tengani syringe ndi dzanja ndi dzanja lanu lamanja, ikani singano ndikudula pakona madigiri 45 kuzungulira khola lake ndikulowetsa pang'onopang'ono mankhwalawo. Tampon yokhala ndi mankhwala ophera tizilombo toyendetsedwa imakanikizidwa kumalo opangira jakisoni, singano imachotsedwa.

Kuopsa kwa mavuto

Kugwiritsa ntchito kashiamu ya nadroparin kungapangitse mapangidwe a zotupa, kukula kwa matupi awo sagwirizana. Nthawi zina pamakhala kuchepa kwa kuchuluka kwa mapulosi m'magazi. Pankhani yoyendetsedwa ndi mankhwala, hematomas, necrosis ya khungu pamalo a jakisoni imatha kuchitika. Mankhwala osokoneza bongo amawonetsedwa ndi magazi ochulukirapo.

Ngati mukukumana ndi zizindikiro zosafunikira, muyenera kusiya kumwa mankhwalawo. Kuti muchepetse mphamvu yogwira ya Fraxiparin, mumakhala mankhwala ochepetsa mavitamini - protamine sulfate kapena hydrochloride.

Zizindikiro zogwiritsidwa ntchito

Kugwiritsa ntchito mankhwalawa kumachitika chifukwa cha mankhwala ake. Kuchita kwake ndikufuna kuchepetsa kugundana kwa magazi, potero amagwiritsidwa ntchito kwambiri popewa thromboembolism komanso pochiza matenda omwe alipo pakubwera kwa magazi.

Zisonyezero zogwiritsa ntchito Fraxiparin:

• Opaleshoni yayikulu ndi mafupa,
• kupewa ndi kuchiza matenda a thrombosis,
• hemodialysis
• angina wosakhazikika ndi kuphwanya kwamanjidwe,
• Chithandizo cha odwala.

Zolemba zogwiritsira ntchito

Kuwonongeka kowonjezereka kuyenera kulipidwa ku malangizo ogwiritsira ntchito mankhwala omwe akukhudzana ndi ochepa maselo heparin, popeza amapezeka m'magawo osiyanasiyana a mankhwala (UNITS kapena mg). Kugwiritsa ntchito Fraxiparin limodzi ndi mankhwala ofananawo pakukhalitsa kwa nthawi yayitali sikuvomerezeka.

Kafukufuku wachipatala sanawonetse zovuta zina pothandizira odwala okalamba. Komabe, gulu ili la odwala liyenera kuwunika momwe impso zisanalandire chithandizo chokhudza kuchepa kwa impso ndi msinkhu.

Timapereka kuchotsera kwa owerenga tsamba lathu!

Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumawopseza mawonekedwe a hyperkalemia. Odwala omwe ali ndi potaziyamu yambiri kapena akuwopsezedwa kuti awonjezeke amayenera kuyang'anitsitsa kuchuluka kwa potaziyamu:

• ndi matenda ashuga
• Ndibwino kuti muchite,
• ndi metabolic acidosis,
• kugwiritsa ntchito mankhwala omwe amasintha mulingo wa potaziyamu.

Mankhwala omwe amakhudza hemostasis amaika chiwopsezo cha hematomas kwa odwala omwe ali ndi catheters a epidural. Zimatenga maola 12 pakati pa jakisoni wa Fraxiparin ndi punction ya lumbar kapena spges analgesia kuti mupewe zovuta.

Zomwe zilipo pazomwe mankhwala amapezeka pa mwana wosabadwayo ndi ochepa, motero tikulimbikitsidwa kupewa nthawi yake. Kupatula komwe kungakhalepo ngati phindu lomwe lingakhale la mzimayi ndilokwera kuposa kuwopseza mwana.

Iwo contraindified mu mankhwala a ana ochepera zaka 18.