Amoxicillin mankhwala a ana

Mankhwala amatengedwa pakamwa. Akuluakulu ndi ana a zaka zopitilira 10 (okhala ndi thupi loposa 40 makilogalamu) amapatsidwa 0,5 g (makapisozi 2) katatu patsiku, matenda operewera, mlingo umakulitsidwa mpaka 1.0 g (makapisozi 4) katatu patsiku. Mulingo waukulu tsiku lililonse ndi 6 g (makapisozi 24).

Zochizira pachimake otitis media, 0,5 g (2 makapisozi) zotchulidwa 3 pa tsiku.

Ana a zaka zapakati pa 5 mpaka 10 (okhala ndi kulemera kwa 20 mpaka 40) amawerengera 0,25 g (1 kapisozi) katatu patsiku.

Njira ya mankhwalawa ndi masiku 5-12 (kwa matenda a streptococcal - osachepera masiku 10).

Kwa odwala okhala ndi chilolezo cha creatinine pansipa 10 ml pa mphindi, mlingo wa mankhwalawa umachepetsedwa ndi 15-50%, ndi anuria, mlingo sayenera kupitirira 2 g patsiku.

Zochizira gonorrhea yosavuta, 3.0 g imayikidwa kamodzi (makamaka kuphatikiza ndi 1.0 g ya probenecid).

Pofuna kupewa endocarditis, 3.0 g imayikidwa kamodzi pa ola limodzi musanachite opareshoni ndi 1.5 g pambuyo pa maola 6-8.

Kuthandizira ndi kupewa matenda a anthrax, achikulire ndi ana olemera 20 makilogalamu amapatsidwa 0,5 g (2 makapisozi) maola 8 aliwonse kwa miyezi iwiri.

Zotsatira zoyipa

Thupi lawo siligwirizana: zotupa za urticaria, khungu, milandu - anaphylactic mantha.

Kuchokera m'mimba: kusintha kwa kukoma, mseru, kusanza, stomatitis, glossitis, dysbiosis, kutsegula m'mimba, kupweteka kwa anus, kawirikawiri - pseudomembranous enterocolitis.

Pa mbali ya chiwindi ndi biliary thirakiti: kuchuluka kwapakati pa hepatic transaminase ntchito, kawirikawiri hepatitis ndi cholestatic jaundice.

Kuchokera ku dongosolo lamanjenje (yogwiritsidwa ntchito kwa nthawi yayitali): kukwiya, nkhawa, kusowa tulo, ataxia, chisokonezo, kusintha kwa machitidwe, kukhumudwa, zotumphukira za m'mitsempha, mutu, chizungulire, kupweteka.

Kusintha kwa labu: leukopenia, neutropenia, thrombocytopenic purpura, kuchepa kwa magazi m'thupi.

Zotsatira zina: kupuma movutikira, tachycardia, interphitial nephritis, kupweteka kwapagulu, matenda a m'magazi ndi kumaliseche, chidwi chachikulu (makamaka kwa odwala omwe ali ndi matenda osachiritsika kapena kuchepa kwa thupi).

Kuchita ndi mankhwala ena

Imachepetsa mphamvu ya estrogen yokhala ndi pakamwa kulera, mankhwala, pakapangira kagayidwe kamene para-aminobenzoic acid imapangidwira, ethinyl estradiol - chiopsezo cha magazi "kupunduka". Imachepetsa chilolezo ndikuwonjezera kawopsedwe a methotrexate. Imathandizira mayamwidwe a digoxin. Zimawonjezera kugwira ntchito kwa anticoagulants osalunjika (kupondereza microflora yamatumbo, kumachepetsa kapangidwe ka vitamini K ndi index ya prothrombin). Kuwunika kwa prothrombin nthawi kuyenera kuchitidwa ndi munthawi yomweyo makonzedwe anticoagulants.

Maantacidid, glucosamine, mankhwala ofewetsa tuvi tochepa komanso amachepetsa, ndipo asidi ascorbic amawonjezera kuyamwa. Excretion imatsitsidwa pang'onopang'ono ndi probenecid, allopurinol, sulfinpyrazone, acetylsalicylic acid, indomethacin, oxyphenbutazone, phenylbutazone ndi mankhwala ena omwe amachepetsa kubisala kwa tubular.

Ntchito ya antibacterial imachepa pogwiritsa ntchito munthawi yomweyo ma bacteriostatic chemotherapeutic othandizira, amawonjezeka ndi aminoglycosides ndi metronidazole. Kutsutsa kwathunthu kwa ampicillin ndi amoxicillin kumawonedwa.

Zolemba zogwiritsira ntchito

Kuchiza kuyenera kupitilizidwa kwa maola ena 48-72 atatha kutha kwa zizindikiro za matenda.

Pogwiritsa ntchito nthawi yomweyo mankhwala okhala ndi pakamwa okhala ndi estrogen komanso amoxicillin, njira zina zakulera ziyenera kugwiritsidwa ntchito ngati kuli kotheka.

Odwala omwe ali ndi vuto la aimpso, kuchepetsedwa kwa mlingo kungafunike.

Zomwe amagwiritsa ntchito mankhwalawa machitidwe a ana:

Wolemba ana osaposa zaka 6 (a fomu iyi)

Zomwe amagwiritsa ntchito mankhwalawa pochita masewera olimbitsa thupi:

Kusintha kwa Mlingo kwa okalamba sikofunikira. Komabe, mwa odwala okalamba, kuchepa kwa impso kumakhala kosavuta, chifukwa chake kusamala kuyenera kuchitidwa posankha mlingo ndikuwunika ntchito yaimpso chifukwa choopsa chomwe chingachitike poyizoni.

Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere. Zomwe zimachitika pa embryotoxic, teratogenic kapena mutagenic zotsatira za amoxicillin mukamamwa pakadali pano sizipezeka. Pa nthawi ya pakati, imagwiritsidwa ntchito pazifukwa zaumoyo, poganizira momwe mayiyo angakhudzire mayi komanso chiopsezo cha mwana wosabadwayo. Kugwiritsa ntchito amoxicillin kumakhudzana ndi mkaka wa m`mawere (ndikofunikira kusiya kuyamwitsa pakumwa). Amoxicillin akudutsa mkaka wa m'mawere, zomwe zingayambitse kukulitsa chidwi cha zinthu mu mwana.

Njira zopewera kupewa ngozi

Mukafuna chithandizo cha nthawi yayitali, ndikofunikira kuwunika momwe ntchito ya ziwalo za hematopoietic, chiwindi ndi impso.

Ndikotheka kukhala ndi superinitness chifukwa cha kukula kwa microflora sazindikira izi, zomwe zimafunikira kusintha kofananirana ndi mankhwala opha maantibayotiki.

Mukafotokozera odwala omwe ali ndi sepsis, kukula kwa bacteriolysis reaction (Yarish-Herxheimer reaction) ndikotheka (kawirikawiri).

Odwala omwe ali ndi vuto laonono amayenera kuyesedwa kwa syphilis panthawi yodziwitsa. Odwala omwe alandila amoxicillin, kuwunika kwa syphilis wotsatira ayenera kuchitika pambuyo pa miyezi itatu.

Ndi chisamaliro ntchito odwala amakonda thupi lawo siligwirizana.

Zotsatira pa kuthekera koyendetsa magalimoto ndi zina zomwe zingakhale nazo

makina owopsa. Gwiritsani ntchito mankhwalawa mosamala kwa anthu omwe akhala akumwa amoxicillin kwa nthawi yayitali.

Zizindikiro zogwiritsidwa ntchito

Amoxicillin wa antioxotic akuwonetsedwa kuti azigwiritsidwa ntchito ndi akulu ndi ana. Mitundu ya kumasulidwa kwa mankhwalawo ndi yosiyana. Kwa akulu, mapiritsi, makapisozi, ufa ndi woyenera, ndipo maantibayotiki ali ngati njira yothetsera, kuyimitsidwa, mapiritsi osungunuka, manyumwa ndi oyenera ana mpaka chaka. Mlingo wa mitundu yonse yomasulidwa ungasiyane.

Mwachitsanzo, mapiritsi ndi makapisozi amatha kukhala 0,0 g, 0,5 g, 0,25 g iliyonse. Mayankho ndi ma ufa owuma amapezeka pamalonda a 125 mg, 375 mg, 250 mg, 400 mg, 500 mg, 1000 mg Ndiwosavuta kubereka musanagwiritse ntchito.

Maantibayotiki omwe ali mgululi amaphatikizira malangizo ogwiritsa ntchito. Zoyimitsa ndi mapiritsi osungunula zimagulitsidwa ndi supuni yoyezera, zomwe zimavuta kuwerengetsa. Mitundu yotereyi yotulutsa maantibayotiki imakonda kulawa, motero, ndi yoyenera kwa ana mpaka chaka.

Amoxicillin akuwonetsedwa kuti agwiritse ntchito ngati mwana ali ndi:

• Matenda a Otolaryngological
• Matenda ndi kutupa kwa impso, kwamkodzo thirakiti,
• Matenda osiyanasiyana, ma causative othandizira omwe ndi tizilombo tating'onoting'ono ta penicillin,
• Kutupa kwam'mimba,
• Zofooka ndi kutupa kwa pakhungu komanso kofewa.

Mankhwala oletsa mankhwalawa amagwiritsidwanso ntchito ngati mwana wapatsidwa mankhwala osokoneza bongo oyamba ndi matenda akulu am'mimba (duodenal ulcer)

Malangizo ogwiritsira ntchito

Malangizo ogwiritsira ntchito amaphatikizapo kumwa mankhwalawa m'njira inayake ndi kumwa, kutengera zaka za mwana. Mwachitsanzo, kwa ana azaka zisanu, madzi kapena kuyimitsidwa ndikoyenera. Kutulutsa mankhwalawa ndi koyenera ngakhale kwa mwana wakhanda. Mukamagwiritsa ntchito kuyimitsidwa, malo ake ayenera kulingaliridwa. Ngati mwana sakhudzidwa ndi maswiti, mutha kumupatsa madzi.

Chepetsa kuyimitsidwa monga momwe atsimikizirira malangizo omwe angagwiritsidwe ntchito. Pakuphika ufa kapena granules, madzi owiritsa okha ndi omwe amafunikira, wozizira kwambiri. Thirani madzi pang'ono mu vial ufa. Sansani chidebe mwamphamvu. Dziwani kuti nthawi yothetsera yankho sikupitilira masiku 14. Malo ozizira, amdima ndi abwino kusunga mankhwala. Kugwiritsira ntchito mankhwalawa ndikofunikira musanadye mlingo uliwonse.

Malangizowo akuwonetsa kuti mwana wochepera zaka zitatu asamapatse 250 mg wa mankhwala kawiri pa tsiku. Mlingo watsiku ndi tsiku uzikhala 500 mg. Kwa ana mpaka chaka chimodzi, mlingo wa mankhwalawo udzatsimikiziridwa ndi adokotala. Njira ya mankhwala opha maantibayotiki imasiyana masiku asanu mpaka khumi ndipo zimatengera kuopsa kwa matendawo komanso momwe wodwalayo alili.

Nthawi zina mumayenera kuwerengera kuchuluka kwake, komwe ndi 20 mg ya antibayotiki pa kilogalamu imodzi ya kulemera kwa munthu. Kuwerengera kotereku kudzachitika ndi adotolo ngati khandalo lidzabadwa kumene. Chifukwa, mwachitsanzo, mlingo wa 250 ndi woyenera kwa mwana wolemera pafupifupi 10 kg. Mwana mpaka chaka, mwachitsanzo, wazaka 9 miyezi, kulemera pafupifupi 20 makilogalamu, adzafunika Amoxicillin, mlingo wa 400-500 mg . Nthawi zambiri, ana amapatsidwa mlingo wotsikirapo, mwachitsanzo, 125 mg. Ndikofunikira kubereketsa mankhwala poganizira kuchuluka kwa mankhwala!

• Kwa ana opitirira zaka zisanu, mlingo wa 500 mg ndivomerezeka. Iyenera kugawidwa m'masiku athunthu ndikupatsidwa kawiri patsiku, 250 mg m'mawa ndi madzulo.
• Ana opitirira zaka khumi ndi akulu omwe amatha kumwa kuchokera ku 500 mpaka 2000 mg ya mankhwalawa patsiku. Mlingo umatengera kuuma kwa matendawa, momwe wodwalayo alili, nthawi zina madokotala amachepetsa mlingo mpaka 125 mg.

Malangizo ogwiritsira ntchito samaletsa kugwiritsa ntchito mankhwalawa amayi oyamwitsa ndi amayi oyembekezera. Komabe, kuchenjeza za zovuta zomwe zingachitike. Mlingo wa mankhwala uyenera kutsimikiziridwa ndi dokotala. Mankhwala amagulitsidwa m'mafakisoni pokhapokha atapereka mankhwala.

Contraindication

Amoxicillin wothandizira maantibayotiki ndiye amathandizira kwambiri pakulimbana ndi mabakiteriya angapo. Mankhwalawa amagwira mabakiteriya okhala ndi aerobic ndi gramu. Koma sikuti nthawi zonse mankhwalawa amatha kutengedwa malinga ndi malangizo. Pali matenda kapena matenda omwe mufunika kuti mupeze mtundu wina kapena maantibayotiki, ndibwino kusiya. Malangizo ogwiritsira ntchito akuwonetsa kukhalapo kwa contraindication pa kumwa mankhwala.

Amoxiclav alibe mphamvu ngati mwana:

Amoxicillin sayenera kugwiritsidwa ntchito ngati mwana:

1. Matenda a virus
2. Matenda a chiwindi kapena impso,
3. Matenda amkatiwo ali pachimake,
4. Kusanza kwambiri kapena kutsegula m'mimba kwambiri.

Komanso, mapiritsi, kuchuluka kwake ndi 125, 250, 375, 400, 500 mg., Sikungathandize ndi fuluwenza kapena SARS, ngati mwana ali ndi chidwi ndi maantibayotiki kapena mwana ali ndi diathesis kapena ulcerative colitis.

Zotsatira zoyipa

Ngati mankhwalawa sanatengedwe moyenera, mavuto omwe angachitike. Zotsatira zoyipa kwambiri za ma antibayotiki ndizosiyanasiyana. Amatha kuchitika ngati zotupa pakhungu, mu mawonekedwe a rhinitis, edema ya Quincke, amatha kukhala ndi mantha a anaphylactic. Pafupipafupi zimachitika chizungulire ndi minyewa kukokana. Zofanana zimatha kuchitika ngati mankhwalawa akhala akugwiritsidwa ntchito kwa nthawi yayitali. Mankhwalawa sayenera kuperekedwa kwa mwana motalika kuposa momwe dokotala amafotokozera.

Kuphatikiza pa zovuta zomwe zimachitika, mwana amatha kukhala ndi mavuto ndi chimbudzi. Kuwonetsera pafupipafupi kumaphatikizapo zinthu monga nseru ndi mawonekedwe a kusanza. Pali kuphwanya kukoma. Kutsegula m'mimba kumatha kuwonekera. Zina zomwe zimachitika chifukwa chogwiritsa ntchito mankhwala osokoneza bongo molakwika ndi monga chiwonetsero cha kusowa tulo, nkhawa, nkhawa, kupsinjika, ndi mutu.

Pali mankhwala ambiri omwe amagwiritsidwa ntchito ndi amoxicillin. Mwachitsanzo, wopanga Russia ku Norton amatulutsa mapiritsi a Solutab. Pali mankhwala amtundu wina wa ku Russia wotchedwa Amoxicillin trihydrate ogulitsa. Wopanga ku Germany amapereka makasitomala a Rathiopharm ndi Amoxillat. Pali analogue yabwino ku Sumamed. Sumamed ali m'mapapu, ma ufa kapena ngati zopangira poyimitsidwa, mu mawonekedwe a ufa wa granular. Kuyimitsidwa ndi koyenera kwa ana. Kuyimitsidwa kokhazikika kumapezeka kwathunthu ndi supuni yoyesera kapena syringe yoyesedwa.

Kampani yopanga mankhwala ku Israeli imapereka fanizo lotchedwa Teva. Mankhwala opha tizilombo a ku Austria amapangidwa ndi kampani Sandoz. Mnzake waku Canada akupezeka pansi pa dzina la Apo-Amoxi. Pali kukonzekera kwa French Butox, Auston Gonoform, Ospamox, Grunamox waku Germany, Indian Danemox, Egypt Emox. Kugulitsa mutha kupeza ma analogu opangidwa ku Bangladesh, Slovenia ndi ena. Mtengo wa analogi ndiwosiyana.

Imodzi mwa mitengo yotsika mtengo kwambiri ndi mankhwala a ku Russia a Amosin. Chimodzi mwa mankhwala otchuka kawirikawiri omwe amagulira ana ndi Flemosin. Mankhwala osokoneza bongo okoma amatha kutafunidwa, kusungunuka m'madzi kapena tiyi, kungameza.

Amoxicillin madzi kuyimitsidwa ndi okwera mtengo. Kwambiri mtengo ndi mankhwala Amoxicillin, amene ali clavuanic acid. Izi zimatchedwa Amoxicillin Amoxiclav - ichi ndi mankhwala ochulukirapo. Amawerengedwa matenda omwewo omwe amoxicillin amachitira. Ana ayenera kumwa amooticlav mosamala ngati pali kuphwanya ntchito ya impso, chiwindi, m'mimba thirakiti. Amoxiclav imakhudzanso ntchito za kulera, zomwe zimamwa piritsi. Amoxiclav sagwirizana ndi mankhwala aminoglycoside. Analogue yotchuka ndi Augmentin. Kuphatikizika kwa mankhwalawa kumaphatikizanso amoxicillin ndi clavulanic acid. Augmentin nthawi zambiri amalembera ana, imaphatikizidwa pamndandanda wamankhwala ofunikira.

Mtengo wa analogi ya gulu la mankhwala a amoxicillin zimatengera wopanga mankhwala ndi mlingo. Amoxicillin amagulitsidwa muyezo wa 250, 500, 1000 mg. Mtengo wa mankhwalawa umachokera ku ruble 36 mpaka 320. Ma Analogs pansi pa dzina la Forte amagulitsidwa m'mapiritsi, mu kipimo cha 500 mg, pamtengo kuchokera ku ma ruble 250.

Russian Amoxicillin Amofast ndiyabwino kwa ana, popeza ili ndi kununkhira kosangalatsa kwa apricot. Mankhwalawa amagulitsidwa pamapiritsi mu 375 mg mpaka 750 mg. Mtengo wa mankhwalawa umachokera ku ruble 75.

Gramox ya mankhwala ndi Amoxicillin yemweyo mu mlingo wa 500 mg, mtengo wake umachokera ku ma ruble 90. Ospamox ikugulitsidwa monga mawonekedwe a makapisozi mu Mlingo wa 250 mg, mtengo wake ndi 300 rubles. Pressmox ikugulitsidwa pamapiritsi mu Mlingo wa 125 mg. Mapiritsiwo amatha kukhala ndi lalanje kapena chinanazi, choyenera ana. Mtengo wapakati wa mankhwala umachokera ku ruble 120.

Mlingo

Mapiritsi a 250 mg

Piritsi limodzi lili

ntchito yogwira - amoxicillin trihydrate 287 mg

(ofanana ndi 250 mg amoxicillin)

obwera: wowuma wa mbatata, calcium kapena magnesium stearate, lactose monohydrate

Mapiritsi oyera kapena oyera okhala ndi tint yachikasu, ozungulira, okhala ndi mawonekedwe ochepa, mbali imodzi ya ngozi

Mankhwala

Pharmacokinetics

Mukamamwa pakamwa, imathiridwa mwachangu komanso pafupifupi (mpaka 93%), ndikupanga kuchuluka kwambiri (1.5- μg / ml ndi 3.5-5 μg / ml, motsatana) pambuyo pa maola 1-2. sizimakhudza mayamwidwe. Kumangiriza kwa mapuloteni a plasma kuli pafupifupi 17%. Imadutsa mosavuta zotchinga za histoeticological, kupatula chotchinga cha magazi chotchinga cha magazi, ndikulowa mu minyewa yambiri ndi ziwalo, imadziunjikira muzochitika zochizira mu zotumphukira zamkodzo, mkodzo, zotupa zamkhungu, kupuma kwapumsi, mapapu (mucosa) maliseche, madzi amkati a pakati, chikhodzodzo cha ndulu ndi bile (yokhala ndi ntchito yachibadwa ya chiwindi), minofu ya fetal. Hafu ya moyo ndi 1-1.5 maola. Ngati vuto laimpso, theka la moyo limakulitsidwa kwa maola 4 - 12,6, kutengera chilolezo cha creatinine.Mwapang'onopang'ono zimapukusidwa kuti apange ma metabolites osagwira. 50-70% imachotsedwa ndi impso zosasinthika ndi canalcium excretion (80%) ndi kusefera kwa glomerular (20%), 10-20% ndi chiwindi. Pang'ono ndikuti amathiridwa mkaka wa m'mawere. Izi zimachitika mphindi 15-30 pambuyo pa kukhazikitsa ndipo zimatha maola 8.

Mankhwala

Amoxicillin ndi anti-spectrum yoteteza ku gulu la semisynthetic penicillin, ndi bactericidal. Imalepheretsa transpeptidase, imasokoneza kaphatikizidwe ka peptidoglycan panthawi yogawa komanso kukula, ndikuyambitsa kuyamwa kwa tizilombo. Yogwira polimbana ndi gram - cocci - Staphylococcus spp. (kupatula penicillinase wotulutsa tinthu tating'ono), Streptococcus spp. Imagwiranso ntchito motsutsana ndi gram-negative aerobic tizilombo: Neisseriamichere,Neisseriameningitidis,Esherichiacoli,Shigellaspp.,Salmonellaspp.,Klebsiellaspp.

Amoxicillin alibe zochizira pafupifupi mitundu yonse yazabwino. Proteus,Klebsiellaspp.,Enterobacterspp.,Serratiaspp.,Pseudomonasspp.,Stenotrophomonasmaltophilia,Choprobacterspp. ndi penicillinase wotulutsa mabakiteriya.

Amoxicillin sagwirizana ndi penicillinase.

Pali mtanda wotsutsa kwathunthu ndi ampicillin.

Zotsatira zoyipa

- khungu hyperemia, zotupa pakhungu, kuyabwa, urticaria, erythema multiforme, matenda a Stevens-Johnson, poyidermerm necrolysis yoopsa, edema ya Quincke

- malungo, kufupika kwa mpweya, rhinitis, conjunctivitis

- kupweteka

- kusintha kwa kukoma, kusanza, kusanza, kutsegula m'mimba, kuchepa kwa matumbo, glossitis, dysbiosis, pseudomembranous enterocolitis

- kuwonongeka kwa chiwindi, kuwonjezeka pang'ono pa "chiwindi" transaminases, hepatitis ndi cholestatic jaundice

- mutu, chizungulire, kukwiya, nkhawa, kusowa tulo,

ataxia, chisokonezo, kusintha kwa machitidwe, kukhumudwa, zotumphukira zamitsempha, zotulukapo zamagetsi

- kusintha kwa leukopenia, kuphatikizapo neutropenia ndi agranulocytosis, eosinophilia

- chosinthika thrombocytopenia, thrombocytopenic phenura, hemolytic magazi

- kutalika kwa magazi nthawi ndi prothrombin nthawi

- wowopsa ndi exfoliative dermatitis, angioedema, anaphylactic zimachitika, seramu matenda, matupi awo a vasculitis, anaphylactic mantha

Zochita zamankhwala osokoneza bongo

Probenecid, Allopurinol, oxyphenbutazone, phenylbutazone, NSAIDs, ndi ena. Mankhwala omwe amaletsa katemera wa canalcine amawonjezera kuchuluka kwa amoxicillin m'madzi a m'magazi. Ndi munthawi yomweyo kugwiritsa ntchito allopurinol, kuwonjezereka kwa pafupipafupi zimachitika pakhungu.

Diuretics imathandizira kumasulidwa kwa amoxicillin, komwe kumapangitsa kuchepa kwa ndende yogwira ntchito m'magazi.

Amoxicillin amachepetsa mphamvu ya njira yolerera yokhala ndi pakamwa ya estrogen ndipo amatha kutuluka magazi pogwiritsa ntchito munthawi yomweyo. Njira zakulera zina zomwe siziri zamafuta zimalimbikitsidwa.

Amoxicillin amachepetsa chilolezo ndikuwonjezera kawopsedwe a methotrexate, amathandizira kuyamwa kwa digoxin.

Mankhwala osagwirizana ndi aminoglycosides.

Ma Bactericidal bacteria (cephalosporin, vancomycin, rifampicin, metranidozole) amakhala ndi synergistic.

Mankhwala osokoneza bongo omwe ali ndi bacteriostatic zotsatira (tetracyclines, erythromycin, macrolides, chloramphenicol, lincosamides, sulfonamides) ali ndi zotsatira zotsutsana ndipo amatha kupangitsa kuti mabakiteriya azigwira.

Maantacid, glucosamine, mankhwala othandizira, chakudya, aminoglycosides amachepetsa ndikuchepetsa kuyamwa kwa amoxicillin.

Ascorbic acid imachulukitsa kuyamwa kwa amoxicillin.

Pogwiritsa ntchito munthawi yomweyo ndi ma anticoagulants, kuwongolera nthawi ya prothrombin ndikofunikira, chifukwa mwayi wambiri wamatenda owonjezereka.

Mafuta a amoxicillin amachepetsedwa pamene amatengedwa patangotha ​​maola awiri atatenga othandizira, monga kaolin. Chifukwa chake, tikulimbikitsidwa kuti muzisamba pakadutsa pafupifupi maola 2 pakati pa kumwa mankhwalawa.

Malangizo apadera

Ndi chisamaliro ntchito odwala amakonda thupi lawo siligwirizana.

Ndi chisamaliro Iyenera kutsegulidwa chifukwa cha kulephera kwa impso, mbiri yakutuluka magazi.

Ndi njira ya chithandizo, ndikofunikira kuwunika momwe ntchito ya magazi, chiwindi ndi impso.

Mwina kukula kwa superinitness chifukwa kukula kwa microflora alibe chidwi ndi izi, zomwe zimafuna kukonza koyenera kwa mankhwala othandizira.

Mankhwala a odwala omwe ali ndi bacteremia, kukula kwa bacteriolysis reaction (zomwe Jarisch-Herxheimer anachita) ndizotheka.

Odwala omwe ali ndi hypersensitivity ku penicillin, zovuta zomwe zimachitika ndi mankhwala a cephalosporin zimatheka.

Mankhwalawa kutsegula m'mimba ndi njira yochiritsira, kugwiritsa ntchito mankhwala antidiarrheal omwe amachepetsa matumbo a matumbo ayenera kupewedwa. Osagwiritsa ntchito matenda am'mimba thirakiti ndi kutsegula kwa nthawi yayitali kapena kusanza, komanso matenda a chiwindi.

Kuphatikiza ndi metronidazole, sikulimbikitsidwa kuti mugwiritse ntchito kwa odwala osakwana zaka 18.

Ntchito pazomwe mukuyendetsa galimoto ndi makina ena owopsa

Poona kuthekera kwa zoyambitsa mavuto, kusamala kuyenera kugwiritsidwa ntchito poyendetsa galimoto ndi njira zina zoopsa.

Mawonekedwe ndi kipimo

Pali mitundu itatu yayikulu yamankhwala yotulutsira - mapiritsi, makapisozi ndi granules. Munthawi zonsezi, chinthu chogwira ntchito ndi amoxicillin mu mawonekedwe a trihydrate. Nthawi yomweyo, makapisozi amapangidwa mu mitundu yosiyanasiyana - 250 mg ndi 500 mg.

Pali mitundu itatu yayikulu ya Amoxicillin yotulutsidwa - mapiritsi, makapisozi ndi granules.

Ma granules adapangira kuyimitsidwa. Ngakhale jakisoni mu ampoules samaperekedwa ndi wopanga aliyense, Invesa amatulutsa kuyimitsidwa kwa jakisoni m'mbale 10 ml.

Zotsatira za pharmacological

Amoxicillin ndi mankhwala osiyanasiyana. Ubwino wake waukulu ndi kuchita bwino kwambiri komanso kuchitapo kanthu mwachangu.

Amoxicillin ali ndi bactericidal motsutsana:

• gram-coc cocci, yomwe imaphatikizapo streptococci, pneumococci, enterococci, staphylococci yokhudza penicillin,
• ndodo zama gramu (corynebacteria ndi listeria),
• gram-negative cocci, yomwe imaphatikizapo ma neysseries,
• timitengo ta gram-hasi (Helicobacter pylori, kupweteka kwa gastritis, komanso hemophilic bacillus, mitundu ina ya enterobacteria).

Amoxicillin amagwiritsidwa ntchito motsutsana ndi Escherichia coli, mabakiteriya a anaerobic, actinomycetes ndi spirochetes, zomwe zimapangitsa borreliosis. Kwa ma virus ochepa, mankhwalawa ali ndi bacteriostatic.

Mankhwala amagwiritsidwa ntchito polimbana ndi tizilombo toyambitsa matenda ambiri amtundu wa matenda opumira. Ndipo ngakhale mankhwalawa akutuluka ampicillin, amawerengedwa kuti ndi othandiza kwambiri chifukwa akonzanso mankhwala a pharmacokinetics - amayamba kuchita zinthu mwachangu, pogwiritsa ntchito mankhwalawa amakhala ndi kuchuluka kwambiri m'madzi a m'magazi komanso tiziwalo timene timagwira ntchito.

Amoxicillin amagwiritsidwa ntchito motsutsana ndi E. coli.

Amoxicillin amatha odzipereka pambuyo pakamwa. The bioavailability wa yogwira ndi 95%. Amoxicillin amalowa pafupifupi mu ziwalo zonse za thupi, kuphatikiza mapapo, chiwindi, minofu, chikhodzodzo, zotupa zonse za zotumphukira (chifukwa chake, zitha kugwiritsidwa ntchito pazotupa zomwe zimayambitsa matenda), pleural, malovu komanso kubisala kwa zolakwazo. M'magazi a cerebrospinal, kuphatikiza kwake kumakhala kotsika, komwe kumapangitsa mankhwala a meningitis.

Amoxicillin ndi mankhwala opanga ma cell omwe amatha kulowa mu zotchinga zina mwa nthawi ya pakati. Komabe, kafukufuku wasonyeza kuti chinthucho sichimalowa mkaka wa m'mawere.

Amoxicillin amadziwika ndi zomanga zochepa m'mapuloteni a plasma - 20% yokha. Imafufutidwa kudzera mu impso pafupifupi osasinthika. Kutha kwa theka la moyo kumapangitsa mphindi 60-90.