Dimaril wa mankhwala: malangizo ogwiritsira ntchito

Chofunikira, ndichochita Diphenhydramine. Limagwirira ntchito amatengera mphamvu zoletsa za mankhwala pakatikati, kolinergic, ndikutseka kwa H3-histamine receptors muubongo. Diphenhydramine imathandizira kuwuma, minyewa ya edema, hyperemia, imalepheretsa kupindika kwa minofu yosalala, imathandizira capillary permeability. Kutenga mitundu pakamwa kumayambitsa kuganiza kwakanthawi kwamkamwa. Mankhwala ali ndi antiparkinsonia, hypnotic, sedative, antiemetic. Chifukwa chakutseka kwa cholinergic receptors, ganglia imachepetsa kuthamanga kwa magazi, ndikuwonjezera zomwe zilipo hypotension. Mwa anthu omwe ali ndi khunyu komanso kuwonongeka kwa ubongo wam'deralo, ngakhale Mlingo wochepa wa Diphenhydramine ungayambitse khunyu, ndipo pa EEG, kutseguka kwa zotulutsa kumadziwika. Mankhwala ndi othandiza kwambiri bronchospasmwokwiyitsidwa ndi kugwiritsa ntchito ma histamine liberals (morphine, tubocurarine). Mankhwala sothandiza kwenikweni kwa bronchospasm ya matupi awo sagwirizana. Ndi Mlingo wobwereza, mapiritsi ogona ndi zotsatira zake zimakhala zowonjezera. Mankhwala amayamba kuchita ola limodzi atatha kumwa, mphamvu yake imatha mpaka maola 12.

Kutulutsa mawonekedwe ndi kapangidwe kake

Mlingo wa diphenhydramine:

Mapiritsi: yoyera, yozungulira yopyapyala yozungulira yokhala ndi bevel (ma ma PC 10. Pakumata matuza, mu katoni ka 1, 2, 3 kapena 5, mapikisoni 10. Mu paketi ya bezeljacheykovy, mu thumba la pepala 1 kapena pamtundu wa makatoni 1, 2 kapena 3 mapaketi, ma PC 10. Kapena ma PC ma 20. M mitsuko yagalasi yakuda, mu mtolo wa makatoni 1 angathe),
Njira yothetsera mtsempha wa intravenous (i / v) ndi makulidwe a intramuscular (i / m): amadzimadzi opanda khungu m'mapiritsi a 1 ml (ma PC 5) M'matumba otupa, mu bokosi la makatoni 1 kapena 2 mapaketi, ma PC 10. Ma PC 10. mumalongedza omata, mu makatoni okhala ndi matumba awiri, mapaketi 10. mu paketi yokhala ndi chikhazikitso, pamakatoni a katoni 1.

Mapiritsi: diphenhydramine hydrochloride, mu 1 pc. - 50 mg
Yankho: diphenhydramine, 1 ml - 10 mg.

Mapale: soluble methyl cellulose yamadzi - 0,326 mg, lactose monohydrate (mkaka wa shuga) - 75 mg, colloidal silicon dioxide (aerosil) - 0,76 mg, chimanga wowuma - 23.154 mg, stearic acid - 0,76 mg,
Yankho: madzi a jakisoni.

Zizindikiro zogwiritsidwa ntchito

Thupi lawo siligwirizana, kuphatikizapo hay fever, urticaria, angioedema,
Hemorrhagic vasculitis,
Allergic conjunctivitis,
Matenda a Seramu
Chorea
Vasomotor rhinitis,
Itchy dermatoses,
Mavuto ogona, monga monotherapy kapena kuphatikiza ndi mapiritsi ogona,
Kubweza pakati
Zowopsa ndi kukhumudwa panyanja,
Meniere's Syndrome,
Kukonzekera.

Contraindication

Zilonda zam'mimba za duodenum ndi / kapena m'mimba,
Mphumu ya bronchial,
Angle -otseka glaucoma,
Chikhodzodzo khosi stenosis,
Hypertrophy of the gland
Khunyu
Hypersensitivity kuti diphenhydramine.

Mosamala komanso mosamala kwambiri, diphenhydramine imalembedwa pa nthawi yoyembekezera komanso nthawi yoyamwitsa, pokhapokha ngati phindu lomwe mayi ali nalo limaposa chiwopsezo cha mwana wosabadwayo kapena mwana.

Mlingo ndi makonzedwe

Mapale: amatengedwa pakamwa. Mlingo wa odwala wamkulu: mapiritsi ogona - 50 mg pogona, mankhwalawa - 30-50 mg katatu patsiku, kwa masiku 10-15. Kwa ana, mlingo umodzi ndi: mpaka wazaka 1 - 2-5 mg, kuyambira 2 mpaka 5 - 5-15 mg, kuyambira wazaka 6 mpaka 12 - 15-30 mg,
Njira yothetsera mtsempha wa intravenous ndi mu mnofu makonzedwe: akulu odwala, jekeseni wa mu mnofu wa 50 mpaka 250 mg, mtsempha wa mtsempha - 20-50 mg. Kunena motsimikizika 1-2 pa tsiku.

Zotsatira zoyipa

Kugwiritsa ntchito diphenhydramine kungayambitse mavuto:

Mwina: kugona, kufupika kwa mucosa wamkamwa, kuchepa chidwi, kufooka kwapafupipafupi, mwa ana - zovuta zam'tsogolo, kugona, kusakoka komanso kusokonekera,
Pafupipafupi: kupweteka mutu, chizungulire, kusokonezeka kwa kayendedwe, nseru, pakamwa pouma, kuwunika, kugwedezeka, malo ogona.

Malangizo apadera

Wodwalayo akulangizidwa kuti apewe kuwonongeka ndi ma radiation a solar panthawi yomwe mumagwiritsa ntchito mankhwalawa, ndikofunikira kusiya kumwa.

Pa nthawi yoyembekezera komanso yoyamwitsa, mankhwalawa ayenera kugwiritsidwa ntchito moyang'aniridwa ndi achipatala.

Amasankhidwa mosamala kwa odwala omwe akuchita nawo mitundu yowopsa ya ntchito, kukhazikitsa komwe kumafunikira kusintha kwakumanga kwa psychomotor ndikuwonjezera chidwi.

Kuyanjana kwa mankhwala osokoneza bongo

Kugwiritsidwa ntchito kwa diphenhydramine kumawonjezera ntchito ya mankhwala omwe amalepheretsa chapakati mantha, kumathandizira machitidwe a ethanol.

Kuphatikizika ndi monoamine oxidase inhibitors (MAO) kumawonjezera ntchito ya anticholinergic ya mankhwala.

Zotsutsana zimachitika motsutsana ndi maziko a mgwirizano ndi psychostimulants.

Kugwiritsa ntchito munthawi yomweyo mankhwalawa kumachepetsa emetic mphamvu ya apomorphine pothandizira poizoni.

Mankhwala amalimbikitsa anticholinergic zotsatira za anticholinergic mankhwala.

Ma Analogs a Diphenhydramine ndi awa: Diphenhydramine-ROS, diphenhydramine-UBF, Diphenhydramine-UVI, Diphenhydramine-Vial, Diphenhydramine Bufus, Dramina, Kalmaben.

Diphenhydramine: mitengo pamafakitale opezeka pa intaneti

DIMEDROL 50mg 10 ma PC. mapiritsi

Diphenhydramine 50 mg mapiritsi 10 ma PC.

DIMEDROL 50mg 10 ma PC. mapiritsi

DIMEDROL 50mg 20 ma PC. mapiritsi

Diphenhydramine 50 mg mapiritsi 20 ma PC.

Diphenhydramine 50mg No. 20

Diphenhydramine (jekeseni) 10 mg / ml yankho la kulowetsedwa ndi mtsempha wa magazi 1 ml 10 ma PC.

DIMEDROL 10mg / ml 1ml 10 ma PC. jekeseni wamitsempha

Diphenhydramine (jekeseni) 10 mg / ml yankho la kulowetsedwa ndi mtsempha wa magazi 1 ml 10 ma PC.

DIMEDROL 10mg / ml 1ml 10 ma PC. yankho la mtsempha wa magazi ndi mu mnofu makonzedwe

Zambiri zokhudzana ndi mankhwalawa ndizofanana, zimaperekedwa pazidziwitso ndipo sizilowa m'malo mwa malangizo ovomerezeka. Kudzipatsa nokha mankhwala kuopsa!

Matenda osowa kwambiri ndi matenda a Kuru. Oimira okha a fuko la Fore ku New Guinea amadwala naye. Wodwala amafa chifukwa cha kuseka. Amakhulupirira kuti chomwe chimayambitsa matendawa ndicho kudya ubongo wa munthu.

Malinga ndi asayansi ambiri, mavitamini zovuta ndizothandiza kwa anthu.

James Harrison wazaka 74 yemwe amakhala ku Australia amakhala wopereka magazi pafupifupi nthawi 1,000. Ali ndi mtundu wamagazi osafunikira, ma antibodies omwe amathandizira akhanda omwe ali ndi vuto lalikulu la magazi kukhala ndi moyo. Chifukwa chake, waku Australia adapulumutsa ana pafupifupi mamiliyoni awiri.

Munthu aliyense samangokhala ndi zala zapadera, komanso chilankhulo.

Pa moyo, munthu wamba amapanga miyala yocheperako yoposa awiri.

Magawo anayi a chokoleti chakuda ali ndi zopatsa mphamvu pafupifupi mazana awiri. Chifukwa chake ngati simukufuna kukhala bwino, ndibwino kuti musadye zopitilira awiri patsiku.

Mwazi wa munthu "umayenda" m'matumbo omwe akukakamizidwa kwambiri, ndipo ngati umphumphu wake waphwanyidwa, amatha kuwombera mpaka 10 metres.

Anthu omwe amakonda kudya chakudya cham'mawa nthawi zambiri amakhala onenepa kwambiri.

Munthu amene amamwa mankhwala opondeleza nthawi zambiri amakhalanso ndi nkhawa. Ngati munthu athana ndi kukhumudwa paokha, ali ndi mwayi wonse wakuyiwalako zamtunduwu mpaka kalekale.

Malinga ndi kafukufuku, azimayi omwe amamwa magalasi angapo a mowa kapena vinyo pamlungu amakhala pachiwopsezo chotenga khansa ya m'mawere.

Kuphatikiza pa anthu, cholengedwa chimodzi chokha padziko lapansi - agalu, omwe ali ndi vuto la prostatitis. Awa ndi abwenzi athu okhulupilika kwambiri.

Kutentha kwambiri kwa thupi kudalembedwa ku Willie Jones (USA), yemwe adamulowetsa kuchipatala ndi kutentha kwa 46,5 ° C.

Pakusuntha, thupi lathu limasiya kugwira ntchito. Ngakhale mtima umayima.

Ntchito yomwe munthu samakonda imakhala yovulaza psyche yake kuposa kusowa kwa ntchito konse.

Ngati mumamwetulira kawiri kokha patsiku, mutha kuchepetsa kuthamanga kwa magazi ndikuchepetsa chiopsezo cha matenda a mtima ndi stroko.

Kusowa pang'ono kwa mano kapena ngakhale adentia yathunthu imatha kukhala kuvulala, ma caries kapena chiseyeye. Komabe, mano otayika amatha kusinthidwa ndi mano.

Kodi diphenhydramine ndi chiyani

Malinga ndi gulu lachipatala lomwe limavomerezeka, Diphenhydramine ndi ya histamine receptor blockers ndi anti antigicgic mankhwala. Zomwe zimapangidwira zimapangidwira ndi diphenhydramine hydrochloride, yomwe imagwira ntchito pakatikati wamanjenje, imalepheretsa histamine ndi mapangidwe a cholinergic okhala ndi ubongo receptors. Chifukwa cha izi, kuphipha kwa minofu yosalala kumachotsedwa, pamakhala mpumulo wa momwe munthu alili ndi chifuwa.

Kupanga ndi mawonekedwe a kumasulidwa

Mitundu yayikulu yakumasulidwa kwa mankhwala ndi yankho la jakisoni ndi mapiritsi. Yoyamba imatha kutengedwa pakamwa kapena kukhazikika m'maso. Kuphatikiza apo, ma rectal suppositories amapangidwa kutengera zomwe zimapangidwa. Kuphatikizika ndi malongosoledwe a kukonzekereraku akuwonetsedwa patebulo:

White cylindrical yoyera yokhala ndi mawonekedwe komanso chiwopsezo

The kuchuluka kwa diphenhydramine, mg

30, 50 kapena 100 pa 1 pc / / 20 ya ana

Madzi oyeretsedwa kuti ajekeseni

Stearic acid, mbatata wowuma, colloidal silicon dioxide, lactose

Ampoules a 1 ml, 10 ma PC. mu paketi yokhala ndi malangizo ogwiritsa ntchito

Matumba kapena matambo a ma 6 kapena 10 ma PC, mapaketi amtundu umodzi uliwonse

Achilengedwe ofunikira a diphenhydramine

Mankhwalawa akukhudzana ndi blockers of histamine receptors mu ubongo. Chifukwa chaichi, diphenhydramine imathandizira kuphipha kwamisempha, imachepetsa mphamvu, imachepetsa mphamvu ya thupi lawo siligwirizana. Yogwira ntchito kwa mankhwala ochititsa kukonzekera omwe ali ndi antiemetic ntchito, kusokoneza, Hypnotic kwenikweni.

Mankhwalawa amayambitsa opaleshoni yam'deralo, yomwe imadziwonekera pakanthawi kochepa kumva kukomoka kwa mucosa wamkamwa, imakhala ndi antispasmodic. Diphenhydramine imakhala yothandiza kwambiri ngati bronchospasm yoyambitsidwa ndi histamine liberalizer (morphine), yocheperako - ngati pali mitundu ya mziwindi. Mankhwalawa ndi osathandiza polimbana ndi mphumu ya bronchial, amatha kuphatikizidwa ndi bronchodilators (Theophylline, Ephedrine).

Diphenhydramine imatsutsana ndi zotsatira za histamine, imawonjezera kuthamanga kwa magazi. Odwala omwe ali ndi kufalikira kwa magazi, kuchuluka kwa ma diphenhydramine kungayambitse kuchepa kwa magazi ndikuwonjezera hypotension chifukwa cha ganglion blocking. Ndi kuwonongeka kwa bongo ndi khunyu, mankhwalawa amatha kuyambitsa matenda a khunyu ndikuyambitsa kuwopsa kwa khunyu.

Mankhwala amayamba kuchita mphindi zochepa, zotsatira zake zimakhala mpaka maola 12. Diphenhydramine imamangiriza mapuloteni a plasma ndi 98%, imapukusidwa mu chiwindi, mapapu ndi impso, zotulutsidwa ndi impso, mkaka wa m'mawere ngati mawonekedwe a conjugate metabolites ndi glucuronic acid. The yogwira thunthu la kapangidwe limalowa magazi chotchinga, kuchuluka kwake kumapezeka mkaka wa m'mawere.

Gulu la Pharmacotherapeutic:

Code ya ATX R06AA02

Zotsatira za pharmacological
Blocker of H1-histamine receptors a m'badwo woyamba. Imaletsa ma H1-histamine receptors ndikuchotsa zotsatira za histamine zolankhulidwa kudzera mtundu uwu wa receptor. Kuchita pa chapakati mantha dongosolo chifukwa blockade wa N₃- histamine zolandila muubongo ndi zopinga za chapakati cholinergic. Ili ndi ntchito yotchedwa antihistamine, yochepetsa kapena yolepheretsa kupindika kwa minofu yolimbitsa thupi, kuwonjezeka kwa chidziwitso, kutupa kwa minyewa, kuyabwa ndi hyperemia. Zimayambitsa opaleshoni yam'deralo (ikagwidwa pakamwa, kufupika kwakanthawi kwamkamwa kumachitika), kumatseka ganglia cholinergic receptors (kutsitsa kuthamanga kwa magazi) ndi dongosolo lamanjenje lamkati, ndipo imakhala ndi mphamvu zoyambitsa, zosokoneza, antiparkinsonia komanso antiemetic. Kukopa ndi histamine kumawonekera kwakukulu pokhudzana ndi kusintha kwakanthawi kwamankhwala am'mimba mu kutupa ndi ziwengo kuposa zomwe zimachitika mwadongosolo, i.e. kutsitsa magazi. Mwa anthu omwe ali ndi vuto laubongo komanso khunyu, amayamba kugwira ntchito (ngakhale utachepa mphamvu) pa EEG ndipo imatha kuyambitsa khunyu. Zowonjezera komanso zotsitsimutsa zimatchulidwa ndi Mlingo wobwereza.
Kukhazikika kwa zochita kumadziwika kuti kwa mphindi 15-60 pambuyo pakulowetsedwa, nthawi ya -12 maola

Pharmacokinetics
Mwansanga mwachangu m'mimba thirakiti. Bioavailability ndi 50%. TCmax - 2040 min (kuphatikiza kwakukulu kumatsimikizika m'mapapu, ndulu, impso, chiwindi, ubongo ndi minofu). Kuyankhulana ndi mapuloteni a plasma - 98-99%. Imalowa mkati mwa chotchinga cha magazi. Amapangidwa makamaka mu chiwindi, pang'ono m'mapapu ndi impso. Amachotseredwa pakhungu patatha maola 6. Hafu ya moyo ndi maola 4 mpaka 10. Masana, amadzazidwa ndi impso mu mawonekedwe a metabolites ophatikizidwa ndi glucuronic acid. Zambiri zimachotsedwa mkaka ndipo zimatha kuyambitsa kusakhazikika kwa makanda (momwe zimachitika modabwitsa.

Zizindikiro zogwiritsidwa ntchito
Allergic conjunctivitis, matupi awo sagwirizana, matenda a urticaria, pruritic dermatoses, dermatographism, seramu matenda, mu zovuta zochizira anaphylactic, Quincke edema ndi zina.
Kusowa tulo, chorea, matenda a Meniere, matenda am'nyanja ndi amlengalenga, ngati antiemetic.

Contraindication
Hypersensitivity, angle-kutsekeka glaucoma, Prostatic hyperplasia, stenosing zilonda zam'mimba ndi duodenum, stenosis ya khosi la chikhodzodzo, mphumu ya bronchial, khunyu.
Zaka za ana mpaka zaka 7 (fomu iyi).

Ndi chisamaliro - mimba, kuyamwa.

Mlingo ndi makonzedwe
Mkati. Akuluakulu ndi ana opitilira zaka 14, 25-50 mg (piritsi 1 / 2-1) katatu patsiku. Mlingo umodzi wapamwamba kwambiri ndi 100 mg, tsiku lililonse - 250 mg. Ndi kusowa tulo - 50 mg 20-30 mphindi pamaso pogona. Ndi matenda oyenda - 25-50 mg maola 4 kapena 4 aliwonse ngati kuli kotheka.
Ana kuyambira wazaka 7 mpaka 14 12.5 - 25 mg (mapiritsi 1 / 4-1 / 2) katatu patsiku.

Zotsatira zoyipa
Kugona, mkamwa youma, dzanzi la mucosa mkamwa, chizungulire, kugwedezeka, nseru, mutu, kufooka, kuchepa kwa psychomotor reaction, photosensitivity, paresis yogona, kusokonezeka kwa mgwirizano. Mu ana, paradxical kukula kwa kusowa tulo, kukwiya komanso kukokomeza ndikotheka.

Bongo
Zizindikiro kukhumudwa kwa chapakati mantha dongosolo, kukula kwa chisangalalo (makamaka ana) kapena kukhumudwa, ana opaka, pakamwa owuma, paresis ziwalo zam'mimba thirakiti, ndi zina zambiri.
Chithandizo: palibe mankhwala apadera. Zaphulika zam'mimba. Ngati ndi kotheka, mankhwala opatsirana: Mankhwala omwe amalimbikitsa kuthamanga kwa magazi, okosijeni, mtsempha wa magazi am'madzi am'magazi.
Osagwiritsa ntchito epinephrine ndi analeptics.

Kuchita ndi mankhwala ena
Imathandizira machitidwe a ethanol ndi mankhwala omwe amalepheretsa ubongo wamkati.
Monoamine oxidase zoletsa timalimbitsa anticholinergic ntchito ya diphenhydramine.
Kuyanjana kwa pakati kumadziwika ndi kuphatikizika kwa psychostimulants.
Kuchepetsa mphamvu ya apomorphine monga emetic pothandizira poizoni.
Imalimbikitsa anticholinergic zotsatira za mankhwala okhala ndi anticholinergic ntchito.

Malangizo apadera
Kusamala ndikofunikira kwa odwala omwe amachita zinthu zomwe zingakhale zoopsa zomwe zimafunikira chidwi chochulukirapo komanso malingaliro amtsogolo. Mankhwalawa ndi diphenhydramine, kudziwika ndi dzuwa ndi ethanol kuyenera kupewedwa.
M'pofunika kudziwitsa dokotala za kugwiritsa ntchito mankhwalawa: antiemetic angapangitse kuti azindikire matenda a appendicitis ndi kuzindikira kwa kuchuluka kwa mankhwala ena osokoneza bongo.
Mu ana 1 mpaka zaka 7, tikulimbikitsidwa kugwiritsa ntchito mapiritsi a 30 mg (kuyambira chaka chimodzi mpaka zaka 3, mlingo wa tsiku lililonse wa 10-30 mg, wogawidwa mu 2-3 Mlingo, kuyambira zaka 4 mpaka 6, mlingo wa 20 - 45 mg wa tsiku lililonse, wogawika 2 -3 kuvomerezedwa).
Mwa ana kuyambira miyezi isanu ndi iwiri mpaka 12, mankhwalawa amatha kugwiritsidwa ntchito ngati ufa womwe wakonzedwa mosungiramo mankhwala ndi ma department opanga ma pharmacies 3-5 mg katatu patsiku.

Kutulutsa Fomu
50 mg mapiritsi
Pa mapiritsi 10 mu blister-strip-free CD kapena mu blister strip pack. Pa 2, 3 kapena 5 mapepala olumikizira pamodzi ndi malangizo ogwiritsira ntchito amayikidwa mu paketi kuchokera pa katoni.

Tsiku lotha ntchito
Zaka 5 Osagwiritsa ntchito mankhwalawa tsiku likatha.

Malo osungira
Lembani B. Mu malo owuma, amdima komanso oti ana sangathe kuwapeza.

Migwirizano ya Tchuthi
Ndi mankhwala.

Wopanga zamabungwe / bungwe:
OJSC "Dalhifarm"
680001, Khabarovsk, St. Tashkent, 22.

Zotsatira za pharmacological

Imakhala ndi antihistamine, antiallergic, antiemetic, hypnotic, mankhwala ochititsa dzanzi. Ma blocks histamine H₁ - zolandila ndikuchotsa zotsatira za histamine zolumikizidwa kudzera mumtunduwu wa receptor. Amachepetsa kapena amalepheretsa kupuma kwa minyewa ya histamine, kuchuluka kwa capillary, kutupa kwa minofu, pruritus, ndi hyperemia. Kukopa ndi histamine kumawonekera kwambiri pokhudzana ndi zochitika zam'mudzimo popewa kutupa ndi chifuwa poyerekeza ndi zomwe zimayambira, i.e. kutsitsa magazi. Amayambitsa opaleshoni yam'deralo (mukamamwa pakamwa, mumakhala ndikumverera kwakanthawi kwakumaso kwa mucosa wamlomo), imakhala ndi vuto la antispasmodic, ndipo imalepheretsa cholinergic receptors a autonomic ganglia (amachepetsa kuthamanga kwa magazi). Mipira N₃ - histamine zolandilira muubongo ndipo zimalepheretsa mawonekedwe apakati a cholinergic. Ili ndi sedative, hypnotic komanso antiemetic. Ndiwothandiza kwambiri kwa bronchospasm yoyambitsidwa ndi libamine ya histamine (tubocurarine, morphine, sombrevin), mpaka kuchepera kwa kugwidwa ndi bronchospasm. Ndi mphumu, siyothandiza ndipo imagwiritsidwa ntchito limodzi ndi theophylline, ephedrine ndi ena bronchodilators.

Pharmacokinetics

Ikamamwa pakamwa, imatha msanga komanso kumva bwino. Amamangidwa ndi mapuloteni a plasma ndi 98-99%. Kuzindikira kwakukulu (C_mosamala) mu plasma zimatheka pambuyo povomerezeka kwa maola 1-4 Ambiri mwa diphenhydramine yotengedwa imapukusidwa mu chiwindi. Hafu ya moyo (T_1/2) ndi maola 1-4. Imagawidwa mthupi, kudutsa chotchinga ndi magazi ndi chotchinga. Kupukutidwa mkaka ndipo kungayambitse kuyambitsa makanda. Masana, amachotsedwa kwathunthu kuchokera mthupi makamaka m'njira ya benzhydrol yolumikizidwa ndi glucuronic acid, komanso ochepa - osasinthika. Kuchuluka kwa zotsatira zimayamba ola limodzi mutatha kumwa, nthawi yayitali kuchokera maola 4 mpaka 6.

Zotsatira zoyipa

Kuchokera kwamankhwala amanjenje ndi ziwalo zam'maganizo: kufooka kwathunthu, kutopa, kusunthika, kutsika chidwi, chizungulire, kugona, kupweteka kwa mutu, kusokonezeka kwa kayendedwe, nkhawa, kuchuluka kwa mkwiyo (makamaka kwa ana), kusokonezeka, mantha, kusowa tulo, chisokonezo, chisokonezo , kunjenjemera, mitsempha, kukomoka, kupweteka kwa m'mimba, kuwonongeka kwa mawonekedwe, diplopia, labyrinthitis, pachimake. Odwala omwe ali ndi vuto laubongo kapena khunyu, amayamba kugwira ntchito (ngakhale utachepa mphamvu) pa EEG ndipo amatha kuyambitsa khunyu.

Kuchokera pamtima ndi magazi: hypotension, palpitations, tachycardia, extrasystole, agranulocytosis, thrombocytopenia, hemolytic anemia.

Kuchokera pamimba: kukamwa kowuma, kutsekeka kwakanthawi kwamlomo, muchulukitsa, kusanza, kupsinjika, kupsinjika, kutsegula m'mimba, kudzimbidwa.

Kuchokera ku genitourinary system: pafupipafupi komanso / kapena kukodza kovuta, kusungika kwamikodzo, msambo.

Pa mbali ya kupuma dongosolo: mphuno youma ndi khosi, mphuno, kupindika kwa bronchial secretion, mwamphamvu pachifuwa komanso kufupika kwa mpweya.

Thupi lawo siligwirizana: zotupa, urticaria, anaphylactic mantha.

Zina: thukuta, kuzizira, photosensitivity.

Bongo

Zizindikiro: mkamwa youma, kupuma movutikira, kulimbikira kwamtundu, kukhudzika kwa nkhope, kukhumudwa kapena kukwiya (nthawi zambiri mwa ana) kwamkati wamanjenje, chisokonezo, mwa ana - kukulitsa khunyu ndi kufa.

Chithandizo: kupatsirana, kutsuka kwamatumbo, kukonza makala, makala omwenso amathandizira posamala kupuma komanso kuthamanga kwa magazi.

M'mapiritsi

Akuluakulu, mapiritsi a diphenhydramine amatengedwa kuchuluka kwa 30-50 mg katatu / tsiku limodzi mwa masiku 10-15. Mlingo umodzi wa ana osakwana zaka 2-5 mg, mwana wazaka 2-5 ayenera kulandira 5-5 mg, wazaka 6-12 - 15-30 mg. Diphenhydramine imagwiritsidwa ntchito ngati piritsi yakugona 50 mg pogona. Ndizosatheka kupitilira muyeso womwe dokotala wakulembani chifukwa chakuwonjezeka kwa chiwopsezo cha zovuta zina. Mapiritsi amatsukidwa ndi madzi, amatengedwa mosasamala kanthu za chakudyacho.

Pazina la "diphenhydramine" suppositories sakupezeka, koma pali zowonjezera zogwiritsidwa ntchito za rectal zomwe zimakhala ndi analgin ndi diphenhydramine, mwachitsanzo, Analdim. Amagwiritsidwa ntchito ngati mankhwala osokoneza bongo pambuyo pa mankhwala oyeretsa, omwe adalowetsedwa mu rectum kawiri / tsiku. Ana wazaka 1-4 wazaka chimodzi amapatsidwa supplementory imodzi, achikulire - 1-3 suppositories. Wamng'ono ngati msinkhu wa mwana, kuchepetsedwa kwa ndende yogwira zinthu kuyenera kuyikidwa. Njira ya mankhwala kumatenga masiku 1-4.

Kuti mugwiritse ntchito ophthalmology kapena allergology, madontho a diphenhydramine ndi omwe amapatsidwa. Mwa izi, 0,2-0,5% mu 2% yankho la boric acid imakhazikika 1-2 kutsikira katatu / tsiku mu conjunctival sac kuti muchepetse ziwopsezo zosiyanasiyana. Njira yothetsera vutoli imatha kuperekedwa kudzera mwa mankhwalawa, kuti muchepetse zizindikiro za chifuwa cha msana ndi sinusitis - 0,05 ml ya mankhwalawa mu mphuno zingapo kangapo / tsiku. Njira yochizira imatsimikiziridwa ndi adotolo, amakufotokozeraninso kuchuluka kwa mankhwalawa.

Diphenhydramine pa nthawi yapakati

Madokotala amapereka mankhwala mosamala pa nthawi yoyembekezera komanso mkaka wa m`mawere, chifukwa diphenhydramine imatha kuyambitsa zotsatira zoyipa za mwana. Musanatenge dokotala kuti aunikire phindu lomwe mayi ali nalo lokhudza chiopsezo kwa mwana wosabadwayo, ndipo ngati ndi lokwera, perekani mankhwala. Ndi kuyamwitsa, diphenhydramine imadutsa mkaka wa m'mawere, ingayambitse kusakhazikika kwa makanda kapena kuwonjezereka kwa kuwonongeka. Ndi mkaka wa m`mawere, mankhwala amatsutsana.

Diphenhydramine ya ana

Simungagwiritse ntchito Diphenhydramine kwa ana popanda upangiri wa dokotala ndipo lingalirani chilichonse payekhapayekha, onani kukula kwa matendawa ndi chizindikiro chogwiritsira ntchito. Kugwiritsa ntchito yankho la makina aberekedwe ndi jakisoni ali contraindified wazaka mpaka miyezi isanu ndi iwiri, mapiritsi a pakamwa makonzedwe - mpaka zaka zisanu ndi chimodzi. Onani mlingo wa mwana mosamala kuti mupewe zovuta zoyambira ndi zovuta kuchita.

Kuyenderana ndi mowa

Malinga ndi kafukufuku, mankhwalawa amathandizira mphamvu ya ethanol yamkati yamanjenje, motero mankhwalawa onse omwe amamwa zakumwa zoledzeretsa kapena zakumwa zoledzeretsa ayenera kutayidwa nthawi zonse munthawi yamankhwala. Kuphatikizidwa kwa mankhwalawa ndi mowa kumakhudza chiwindi, zomwe zimapangitsa chiwopsezo cha mankhwala osokoneza bongo komanso poyizoni wa metabolites.

Migwirizano yogulitsa ndikusunga

Mankhwalawa amaperekedwa ndi mankhwala, osungidwa ndi ana pamalo amdima pamtunda wosaposa 30 digiri zaka zisanu.

Pali mitundu ingapo ya mankhwala ofanana omwe ali ndi ntchito yomweyo. Zogulitsanso mankhwala osokoneza bongo omwe ali ndi ziwalo zina, koma zimathandizanso m'thupi. Mankhwala otchuka:

Diphenhydramine mankhwala enaake,
Diphenhydramine,
Allergan,
Diphenyl
Onaninso
Alledril
Mdyerekezi

Mutha kugula mankhwala m'masitolo ogulitsa pa intaneti. Mtengo wa mankhwalawa umatengera mtundu (mapiritsi / yankho), gawo lamalonda ndikuyambitsa ntchito yogwira. Mitengo ya mankhwala osungirako mankhwala ku Moscow yasonyezedwa patebulopo:

Ampoules 1 ml 10 ma PC.

Mapiritsi 50 mg 10 ma PC.

Veronika, wazaka 28. Ndili ndi vuto la kusowa tulo, sinditha kugona, kugwedezeka ndi kutalika kwa nthawi yayitali, m'mawa wotsatira ndimadzuka ndikusweka. Izi zimawononga molakwika luso logwira ntchito. Mzanga adandiwuza kuti nditenge bothenhydramine Tablet usiku kangapo pa sabata. Ndinamvera, ndikukhuta. Mankhwala amachepetsa, samayambitsa nseru komanso "zolephera" zakuthwa pogona.

Leonid, wazaka 38. Masika aliwonse ndimayamba kuterera ndikukhosomola, chifukwa masamba ake akutulutsa maluwa, mitengo yatulutsa. Ndili ndi ziwopsezo, madontho a diphenhydramine okha omwe amatha kuthana ndi izi. Ndimaziyika m'maso kuti ndichepetse kutupa ndi kubowola, nthawi zina ndimatha kulowa mu mphuno yanga kuti ndichotse mphuno. Mankhwalawa ndi abwino, ndipo ndiokwera mtengo, osati monga njira zamakono.

Elizabeth, wazaka 32. Mwezi watha ndinakumana ndi vuto la mtima. Ntchito imalumikizidwa ndi mankhwala apakhomo, ndipo thupi lachita. Kwa nthawi yayitali ndimafuna yankho lomwe lingandithandize, pamapeto pake ndinakhazikika pamapiritsi a Diphenhydramine. Ndimamwa usiku, chifukwa mankhwalawa amayambitsa kugona mkati mwa masana, ndimapuntsanso mawanga ndi zonona. Pali kupambana, koma osati mwachangu momwe ndimafunira.

Vitaliy, wazaka 41. Kwa nthawi yoyamba mwezi ndi theka zapitazo, ndinali kukumana ndi vuto lakunyanja, ndipo ndinayamba kudwala mgalimoto. Ndidamva kuti diphenhydramine imagwira bwino ntchito ndi matenda, ndidaganiza zoyamba kuchita. Mankhwalawa adatha kale - amakupangitsani kugona, chifukwa chake sitikunena za kuyendetsa. Ndikuyang'ana chithunzi chamakono cha Diphenhydramine kuti ndiyendetse galimoto ndekha.

Mapiritsi a diphenhydramine, malangizo ogwiritsira ntchito

30-50 mg imodzi mpaka katatu patsiku, nthawi ya mankhwala ndi masiku 10-15.

Ndi kusowa tulo 50 mg ndi theka la ola asanagone.

At postencephalic, idiopathic parkinsonism koyamba kutumikiridwa 25 mg katatu patsiku, muyezo wotsatira mlingo umayamba kuchulukitsidwa mpaka 50 mg 4 pa tsiku.

Ndi matenda oyenda maola 6 aliwonse muyenera kumwa mapiritsi 25-50 mg.

Kuchita

Diphenhydramine imathandizira pa zochita za mankhwala omwe amalepheretsa mitsempha. Akaphatikizidwa ndi psychostimulants zochita zotsutsa zalembedwa. Mao zoletsa kuwonjezera anticholinergic ntchito ya mankhwala. Mankhwalawa poizoni, kuledzera, mankhwalawa amachepetsa kugwira ntchito apomorphine.

Diphenhydramine ndi mowa

Amadzipatsa kuti amwe mankhwala osokoneza bongo. Zotsatira za mowa zimapangidwira, zotsatira za hypnotic zimachulukitsidwa, kuwonongeka kwakukulu kwa thupi ndikotheka. Zotsatira zake sizingaloseredwe, makamaka pogwiritsa ntchito waukulu. Vodka yokhala ndi diphenhydramine imatha kukhala chakumwa chomaliza m'moyo wa munthu amene amamwa chisakanizo ichi, mlingo wowopsa ukhoza kukhala wochepa kwambiri akaphatikizidwa ndi mowa.