Maso amtundu wa Gentamicin: malangizo ogwiritsira ntchito

Maso amtundu wa Gentamicin ndi mankhwala othandizira omwe amafunidwa kuti azigwiritsa ntchito mwadongosolo.

Diso latsika Gentamicin ndi mankhwala othandizira

Madontho amakhala ndi zotsatira zabwino m'maso, amapanga chipolopolo choteteza ndikubwezeretsa kumveka kwamasomphenya.

Zochita zamankhwala

Gentamicin imakhala ndi zotsatirapo zingapo zotsutsana ndi antimicrobial. Momwemo, imakupatsani mwayi wolimbana ndi matenda ambiri omwe amayamba chifukwa cha mabakiteriya oyipa.

Madontho a maso a Gentamicin amagwiritsidwa ntchito pazotsatira zotsatirazi:

1. Blepharitis.
2. Keratitis
3. Conjunctivitis.
4. Zowonongeka zam'maso.
5. Pofuna kupewa kulowererapo.
6. Ndi zoyaka.
7. Zilonda zam'mimba.
8. Iridocyclitis.
9. Zowonongeka zam'maso.

Izi pamwambapa ndi matenda akulu okha omwe mankhwalawa amatha kuthana nawo. M'malo mwake, mndandandawu ukupitilira kwa nthawi yayitali.

Diso limaponya malangizo a Gentamicin kuti agwiritse ntchito

Ana atatha zaka 12 ndi akulu ayenera kukhazikitsa dontho limodzi kapena awiri mumaso omwe akhudzidwa kwa katatu patsiku. Kutalika kwovomerezeka kwa masiku 14. Koma, zonse zimatengera matenda komanso momwe thupi la munthu liliri.

Komanso, othandizira amatha kugwiritsa ntchito prophylaxis isanayambe kapena itatha kuchitidwa opaleshoni. Itha kukhala:

1. Kuchotsa zinthu zakunja.
2. Kuwotcha.
3. Panthawi yowonongeka.

Poterepa, ndikofunikira kukhazikitsa dontho limodzi katatu pa tsiku kwa masiku atatu motsatizana.

Zotsatira zoyipa ndi contraindication

Zotsatira zoyipa, titha kusiyanitsa:

Simungagwiritse ntchito chida chotsatira:

1. Pa nthawi yoyembekezera.
2. Pa mkaka wa mkaka.
3. Ana osakwana zaka 12.
4. Ndi mitsempha yam'mitsempha yamagetsi.
5. Matenda aimpso.
6. Uremia.
7. Komanso, simungagwiritse ntchito mankhwalawa ngati pali zovuta zina.

Tikuyang'ana! Osagwiritsa ntchito diso la Gentamicin limatsika mopitirira kasanu patsiku. Izi zingayambitse kutupa kwa ziphuphu zakumaso.

Ngati pali chimodzi mwazizindikiro zomwe zalembedwa, ndiye kuti muyenera kukana kumwa mankhwalawo ndikuonana ndi dokotala.

Malangizo apadera ogwiritsa ntchito

1. Osakhudza kumtunda kwa wobayira - izi zingayambitse matenda.
2. Chotsani magalasi mphindi 15 musanayikidwe.
3. Chogwiritsidwacho chimatha kuchepetsa kuwona, chifukwa chake muyenera kusiya maulendo kumbuyo kwa gudumu.
4. Moyo wa alumali wa madontho ndi zaka ziwiri.
5. Ngati botolo lotseguka, muyenera kuligwiritsa ntchito pakatha milungu 4.

Mtengo wapakati wamaso umatsika Gentamicin muma pharmacies aku Russia tsopano ndi ma ruble 200-250. Ngati timayankhulira Ukraine, ndiye kuti mtengo wawo umakhala m'dera la 70-80 UAH.

Zotsatira za pharmacological

Gentamicin imadziwika ndi mawonekedwe osiyanasiyana a antimicrobial zochita. Imagwira pa mabakiteriya ambiri opanda gramu: Escherichia coli, Klebsiella spp., Indole-positive and indole-negative Proteus spp., Enterobacter spp.l Providencia stuartii, Salmonella spp., Shigella spp., Acinetobacter spp, Pseudomonas aeruginosa: gram Staphylococcus spp. (kuphatikiza zomwe sizigwirizana ndi penicillin ndi maantibayotiki ena), mavuto ena a Streptococcus spp. Kukana kwa tizilombo tating'onoting'ono tating'onoting'ono kumayamba pang'onopang'ono, komabe, zovuta zosagwirizana ndi neomycin ndi kanamycin zimagwiranso ndi mankhama.

Zizindikiro zogwiritsidwa ntchito

Gentamicin imapangidwira zochizira matenda oyambitsidwa ndi tizilombo toyambitsa matenda omwe amayambitsa matendawa. Mankhwalawa adapangidwa kuti apangidwe ndi conjunctivitis yovuta kwambiri komanso yotupa, zilonda.-G za cornea, keratitis, keratoconjunctivitis, pachimake komanso matenda iritis, pachimake ndi G, blepharitis, blepharoconjunctivitis, dacryocystitis ndi matenda ena opatsirana, otupa a m'maso, komanso kupewa. opaleshoni yamaso.

Contraindication

Hypersensitivity to gentamicin kapena chilichonse cha mankhwala, aminoglycosides ena.

Pali umboni wosonyeza kuti mankhwalawa amatha kuyambitsa neuromuscular blockade, motero amatsutsana mu myasthenia gravis ndi matenda ena. Mankhwalawa ali contraindicated mu kukhathamiritsa kwa membrane wa tympanic, aimpso kuwonongeka, matenda a wamitsempha, vetibular zida, e, pa mimba ndi kuyamwitsa (siyani kuyamwitsa pa chithandizo).

Zotsatira zoyipa

Popeza palibe maphunziro aposachedwa azachipatala omwe angagwiritsidwe ntchito kuti azindikire kuchuluka kwa zotsatira zoyipa, kufulumira kwa zoyipa zonse zomwe zalembedwa pansipa zimawerengedwa kuti "pafupipafupi osadziwika".

Kuchokera kumbali ya gawo la masomphenyawo: mphamvu zakumaloko, kuwona kwakhungu, kusachedwa kwamaso, kumva kuyaka, kuyabwa m'maso, mphamvu yofiyira, kutupa.

Kuchokera mbali ya rut ndi subcutaneous zimakhala: kuyaka moto, kugunda, kuyabwa, khungu.

Kuchokera ku genitourinary dongosolo: nephrotoxicity, pachimake aimpso kulephera.

Nthawi zina, thupi limakhala losatheka.

Pakukhumudwitsa, kukhudzika mtima kapena kugwiritsa ntchito mankhwalawa, kugwiritsa ntchito mankhwalawa kuyenera kusiyidwa ndipo chithandizo choyenera chikuyenera kuperekedwa.

Kuchita ndi mankhwala ena

Pogwiritsa ntchito munthawi yomweyo kugwiritsa ntchito mankhwala ofanana am'mototic acid ndi furosemide, chiwopsezo cha ototoxicity chimawonjezeka, pomwe amphotericin B, cisplatin, cyclosporine ndi cephalosporins amatha

zolimbikitsa nephrotoxicity. Mankhwala sangathe kulembedwa

ndi mankhwala ena operekera

nephrotoxic zotsatira. Neuromuscular blockade ndi kupuwala ziwalo zinali

Kulembetsa akamalemba aminoglycosides kwa odwala omwe amalandila panthawi

opaleshoni ya minofu yopumitsa monga curre. Mankhwala osagwirizana ndi amphotericin,

cephalosporins, erythromycin, heparin, penicillin, sodium bicarbonate ndi

Zolemba zogwiritsira ntchito

Kukopa pa kuyendetsa magalimoto ndi njira zina zowopsa. Kusamala kuyenera kuchitidwa poyendetsa, kugwiritsa ntchito zida zamafuta kapena kuchita ntchito zina zowopsa. Mankhwalawa amatha kuyambitsa kuwonongeka m'maso. Ngati mukukumana ndi vuto lakukhazikika, pewani kuchita zoopsa.

Njira zopewera kupewa ngozi

Pewani kugwiritsa ntchito nthawi yayitali, zomwe zingayambitse chidwi cha khungu komanso kutuluka kwa tizilombo toyambitsa matenda. Kutengeka kwamtanda kwamtundu wina kumatha kukhala ndi aminoglycoside maantibayotiki ena. Matenda akulu, kugwiritsidwa ntchito kwa mankhwalawa kuyenera kuthandizidwa ndikugwiritsa ntchito mankhwala a antiotic. Chenjezo limalangizidwa popereka mankhwala munthawi yomweyo ndi zokhudza zonse aminoglycosides. Ndi chithandizo cha nthawi yayitali, impso ndi makutu zimayenera kuyang'aniridwa. Madontho amaso sayenera kugwiritsidwa ntchito kwa odwala omwe amavala magalasi.

Kutulutsa mawonekedwe, ma CD ndi kapangidwe kake Gentamicin

Diso limagwera ngati mawonekedwe amtundu wowonekera, wopanda utoto kapena wachikasu.

1 ml
mankhwalawa sulfate	5 mg
zomwe zimagwirizana ndi zomwe zili glamicin	3 mg

Othandizira: benzalkonium chloride, sodium hydrogen phosphate, sodium dihydrogen phosphate, sodium chloride, madzi.

5 ml - botolo la polyethylene dontho (1) - mapaketi a makatoni.

Zisonyezo za mankhwala Gentamicin

Matenda opatsirana amaso:

• blepharitis
• conjunctivitis
• keratoconjunctivitis,
• keratitis
• dacryocystitis
• iridocyclitis.

Kupewa matenda opatsirana pambuyo pakuvulala ndi machitidwe a maso.

Nambala za ICD-10

Khodi ya ICD-10	Chizindikiro
H01.0	Blepharitis
H04.3	Kutupa kovuta komanso kosadziwika kwa zotchingira bwino
H04.4	Kutupa kosalekeza kwa ma ducts a lacrimal
H10.2	Zina pachimake conjunctivitis
H10.4	Matenda a conjunctivitis
H10.5	Blepharoconjunctivitis
H16	Keratitis
H16.2	Keratoconjunctivitis (kuphatikiza chifukwa chowonekera kunja)
H20.0	Pachimake ndi subacute iridocyclitis (anterior uveitis)
H20.1	Matenda a iridocyclitis
Z29.2	Mtundu wina wa chemotherapy (antiotic prophylaxis)

Kuyanjana kwa mankhwala osokoneza bongo

Kugwirizana ndi erythromycin ndi chloramphenicol sikulimbikitsidwa chifukwa cha kusagwirizana kwa mankhwala.

Pakakhala vuto la mabakiteriya amaso, mankhwalawa amayenera kuthandizidwa ndikugwiritsa ntchito maantibayotiki, komabe, kugwiritsa ntchito madontho a maso a Gentamicin sikuyenera kuphatikizidwa ndi maantibayotiki ena omwe ali ndi zotsatira za oto- ndi nephrotoxic.

Kuphatikizika ndi katundu

Gentamycinum monga mawonekedwe a madontho ndi yankho lomveka bwino lomwe limatsanulidwa m'mabotolo apulasitiki okhala ndi dontho la kosavuta pokonzekera mankhwalawa. Kuphatikizidwa kwa mankhwala a ophthalmic kumakhala ndi magawo awiri omwe amagwira ntchito: giratethasone sodium phosphate ndi dexamethasone. Kukonzekera kotereku kumapereka njira yolimbanira yolimbana ndi bakiteriya wa gram-negative aerobic ndi magalamu ambiri + cocci.

Kuphatikiza pa kutchulidwa kwa antibacterial, Gentamicin ili ndi mphamvu yotsutsa-yotupa komanso yofatsa.

Kapangidwe ka madontho amaso mumakhalanso zinthu zothandiza, monga:

• d / ndi madzi
• mchere wa hydrochloric acid,
• benzazhexonium chloride,
• phosphoric acid potaziyamu mchere,
• dipotassium hydrogen phosphate.

Kuti wodwalayo achotse mwachangu odwala omwe ali ndi vuto lalikulu la matendawa, ndikofunikira kuthandizira mankhwalawa ndi mankhwalawa osanunkha kanthu.

Gentamicin imapangidwira kuti azigwiritsa ntchito ziwindi. Zida zake sizilowa m'magazi ambiri ndipo sizikhala ndi dongosolo lililonse. Chifukwa chake, mukudwala kwambiri, ndikofunikira kugwiritsa ntchito madontho amaso osakanikirana ndi mankhwala a antibacterial omwe ali ndi mitundu inanso ya Mlingo.

Maikidwe

Malangizo ogwiritsira ntchito amafotokozera ma pathologies otsatirawa, pakuwonetsetsa komwe kugwiritsidwa ntchito kwa maso akutsikira "Gentamicin" ndikofunikira:

• matupi awo sagwirizana ndi kutupa
• pachimake puruse yotupa yotupa ya eyelash tsitsi
• kutupa kwa conjunctiva, mbali yakumaso.

Gentamycinum imalembedwa kwa odwala omwe amachitidwa opaleshoni ya glaucoma, matenda amtundu wamatumbo kapena matenda ena othandizira opaleshoni. Potere, mothandizidwa ndi mankhwala ophatikizika, ndizotheka kupewa zovuta zomwe zingachitike ndikuletsa njira zotupa zomwe nthawi zambiri zimachitika mu nthawi ya postoperative.

Malangizo ogwiritsira ntchito

Madontho a Gentamicin ndi oyenera akuluakulu ndi ana. Muyenera kuzigwiritsa ntchito, kutsatira malamulo awa:

1. Sambani m'manja ndi sopo musanachitike.
2. Pukutani kope lakumanzere ndikumasulidwa madontho 1-2 a yankho mu conjunctival sac.
3. Bwerezani kuyika maola anayi aliwonse.
4. Kutalika kwa nthawi ya maphunzirowa sikuyenera kupitirira masabata awiri.
5. Panthawi ya njirayi, muyenera kuonetsetsa kuti nsonga ya botolo sigwire diso ndi zina.

Bweretsani ku zomwe zalembedwa

Kuchepetsa malire ndi zovuta zina

Kugwiritsa ntchito "Gentamicin" kudzakhala kowopsa kwa odwala omwe ali ndi matenda monga:

• chifuwa chachikulu cha diso,
• zotupa zamavalidwe
• kukonzanso kwa kukokoloka kwa ziphuphu,
• matenda oyamba ndi maso
• zilonda ndi kuwonongeka kwa ziphuphu,
• matenda limodzi ndi kuchuluka intraocular anzawo.

Pamene mayi akuyamwitsa, sayenera kugwiritsa ntchito mankhwalawa ndi mankhwalawa.

Mndandanda wa contraindication uli ndi hypersensitivity kapangidwe ka madontho amaso, nthawi ya mkaka wa m'mawere ndi pakati. Pambuyo pokhazikitsa maso, "Gentamicin" ikhoza kuyambitsa kuchepa kwakanthawi kwakanthawi kawonedwe, pamenepa, mu theka loyamba la ola kapena mpaka mawonekedwe osawoneka bwino, osavomerezeka kuyendetsa ndikuyamba ntchito yomwe imafuna chidwi chachikulu.

Mankhwala a ophthalmic pathologies a Gentamicin akutsikira, zotsatirazi zotsatirazi zingayambike:

• kuchuluka kwa kuthamanga kwamadzi mkati mwa diso,
• Kutulutsa kwa khungu lanu,
• zilonda zamiyendo
• zotupa za m'matumbo amkamwa ndi m'maso,
• kutupa kwamitsempha,
• kusanza kwa ophunzira.

Bweretsani ku zomwe zalembedwa

Kuopsa kwambiri

Popeza zigawo zikuluzikulu za Gentamicin sizilowa munjira yamagazi, ndipo mankhwalawo akagwiritsidwa ntchito kunja, chiopsezo chokhala ndi bongo chochepa kwambiri. Komabe, pogwiritsa ntchito ma dontho a maso kwa nthawi yayitali, ma glaucoma a steroid komanso kugwetsa maselo m'maso kumachitika. Popeza mwakhazikitsa njira yochulukirapo yothetsera vuto lanu m'maso, muyenera kuwatsuka nthawi yomweyo pamadzi otentha.

Kugwirizana

Opanga Gentamicin salimbikitsa kuti aphatikize ndi Erythromycin ndi Chloramphenicol chifukwa chosagwirizana ndi mankhwala. Ngati mankhwala ena othandizira maso adayikidwa limodzi, ndiye kuti mphindi 20 ziyenera kuchitika pakayendetsedwe kake. Kukonzekera konse komwe kumagwiritsidwa ntchito ndi Gentamicin kuyenera kudziwitsidwa kwa dokotala - ophthalmologist.

KODI ZIKUKHUDZANI KUTI MUKABWERETSA ZOONA ZOTSATIRA ZAULEMU?

Poona kuti mukuwerenga izi tsopano, kupambana polimbana ndi masomphenya osakhazikika kulibe kumbali yanu.

Ndipo mudaganizapo kale za opaleshoni? Ndizomveka, chifukwa maso ndi ofunikira kwambiri, ndipo magwiridwe ake ntchito ndi chinsinsi cha thanzi komanso moyo wabwino. Kupweteka kwambiri m'maso, kuthina, malo akuda, kumva thupi lachilendo, kuuma, kapena mosemphanitsa, maso amadzi. Zizindikiro zonsezi mumazidziwa nokha.

Koma kodi ndizotheka kuchitira zomwe zimayambitsa m'malo mothandizira? Timalimbikitsa kuwerenga nkhani ya Yuri Astakhov, yomwe adalimbikitsa kuti ichitike. Werengani nkhani >>