Chepetsani Kukhathamiritsa Kwambiri Carbon Cholesterol
Yoyambitsa kaboni lowers lipids, cholesterol ndi triglycerides m'mwazi seramu, chiwindi, mtima ndi ubongo.
Pa kafukufuku wina wokhudza odwala omwe ali ndi cholesterol yambiri, lofalitsidwa mu Ogasiti 1986 m'magazini ya Britain, The Lancet, supuni ziwiri (8 magalamu) zama makala omwe adachitika amatenga katatu patsiku kwa masabata anayi adatsitsa cholesterol yonse ndi 25%, LDL ndi 41% ndipo idachulukitsa HDL / LDL (lipoproteins high / density lipoproteins).
Kafukufuku wina wofalitsidwa mu magazini ya Kidney International Supplement (Juni 1978) adawonetsa kuti kaboni yokhazikitsidwa imatha kuchepetsa kwambiri serum triglycerides (mpaka 76%) mwa odwala omwe ali ndi vuto lalikulu la hyperlipidemia. Olembawo ananena kuti "malasha angagwiritsidwe ntchito poyang'anira matenda a shuga a azotemic ndi nephrotic hyperlipidemia."
Zotsatira izi zidatsimikizidwanso mu kafukufuku waku Finnish yemwe adasindikiza mu European Journal of Clinical Pharmacology mu 1989. Ofufuza kuchokera ku dipatimenti ya Clinical Pharmacology ya University of Helsinki adatsimikiza ubale wogwiritsa ntchito mankhwalawo akamagwiritsa ntchito makala kuti atsitse mafuta a serum cholesterol, komanso kuyerekeza zomwe zimachitika chifukwa cha makala ndi cholestyramine, mankhwala ochepetsa cholesterol, odwala odwala hypercholesterolemia. Pakufufuza kwapadera, ophunzira 7 amatenga 4, 8, 16 kapena 32 g wa kaboni yoyambitsa tsiku, komanso chinangwa, kwa milungu itatu. Mlingo wa cholesterol wathunthu ndi LDL unachepa (wokwera ndi 29% ndi 41%, motsatana), ndipo chiŵerengero cha HDL / LDL chinawonjezeka (pazambiri 121%) modalira mlingo. Odwala ena khumi omwe ali ndi vuto lalikulu la hypercholesterolemia amalandila tsiku lililonse kwa milungu itatu, mwatsatanetsatane, makala makala 16 g, cholestyramine 16 g, makala othandizira 8 g + cholestyramine 8 g, kapena chinangwa. Kuzungulira kwa cholesterol yathunthu ndi HDL kunachepa ndikugwiritsa ntchito kaboni yodziyambitsa (ndi 23% ndi 29%, motsatana), cholestyramine (mwa 31% ndi 39%) ndi kuphatikiza kwawo (pofika 30% ndi 38%). Chiwerengero cha HDL / LDL chinakwera kuchoka pa 0,13 mpaka 0,23 kwa kaboni yokhazikitsidwa, kupita ku 0,29 wa cholestyramine, komanso mpaka 0.25 ikaphatikizidwa. Serum triglycerides inachuluka ndi cholestyramine koma osayambitsa makala. Magawo ena, kuphatikiza ma seramu omwe ali ndi mavitamini A, E ndi 25 (OH) D3, sanasinthe. Kugwiritsa ntchito chinangwa kwa milungu itatu kokha kumachepetsa gawo la lipids. Ponseponse, kuvomerezedwa ndi kuleza mtima ndikuyenda bwino kwa makala ophatikizidwa, cholestyramine ndi kuphatikiza kwawo kunali kofanana, koma panali zomwe aliyense amakonda payekhapayekha.
Kuphatikiza apo, kuyesa kwa microscopic kwa minofu kumawonetsa kuti tsiku lililonse kaboni yokhazikitsidwa imatha kulepheretsa kusintha kwa ma cell ambiri okhudzana ndi ukalamba - kuphatikizapo kuchepa kwa mapuloteni, kuchepa kwa ntchito ya RNA, michere ya microsis, komanso kusintha kwa sclerotic mumtima ndi m'mitsempha ya coronary.
Yoyambitsa Carbon Action
Cholesterol okwera nthawi zonse imayambitsa matenda a mtima kapena sitiroko, chifukwa chomwe munthu amafa chifukwa chobowoka m'mitsempha ya m'mtima kapena muubongo. Cholesterol imapezeka m'thupi momwe amapangira - lipoprotein yapamwamba komanso yotsika. Chiwerengero chachikulu cha omwe kale - HDL - imawonetsedwa ngati chizindikiro cha thanzi labwino, ndipo kuchuluka kowonjezereka - LDL - ndizowopsa kwa thupi, popeza ndi iye amene amayambitsa atherosclerosis.
Mu Ogasiti 1986, mtolankhani Wachingelezi, The Lancet, adafalitsa zotsatira za kafukufuku yemwe amachitika ndi anthu omwe ali ndi cholesterol yayikulu. Zinapezeka kuti 8 g (2 tbsp.) Patsiku lililonse la mpweya wolowetsedwa mu 3 mgulu wogawika amachepetsa cholesterol yokwanira ndi 25%, LDL - ndi 41%. Kuyesaku kunachitika masiku 28. Adatsimikiza kuti kuchuluka kwa HDL / LDL kumawonjezeka nthawi 2.
Pambuyo pazaka 3, imodzi mwa masunivesite ku Finland adayerekezera zomwe zimachitika chifukwa cha mpweya ndi cholestyramine - mankhwala ochepetsa cholesterol. Kuyesaku, komwe kunatenga masiku 21, kunakhudza odwala omwe ali ndi vuto lalikulu la hypercholesterolemia. Zotsatira zake, zidakwaniritsa izi:
- Odwala omwe amatenga kaboni 16 g ka activated patsiku, kuchuluka kwa cholesterol kutsika ndi 23%, HDL - pofika 29%, chiŵerengero cha HDL / LDL chinakwera kuchoka pa 0.13 mpaka 0.23,
- kwa iwo omwe adatenga 16 g patsiku la cholestyramine, zizindikirozi zidasintha ndi 31% ndi 39% ndikufika ku 0.29, motsatana.
- Mukamwa 8 g wa activated kaboni ndi 8 g wa cholestyramine - ndi 30%, 38% ndi mpaka 0.25.
Tinaganiza kuti kupindula kwa ndalama zokhala ndi cholesterol yayikulu m'mitundu yonse itatu ndi yofanana, kuyambitsa kaboni kumachitika chimodzimodzi monga chida chapadera.
Kugwiritsa ntchito yankho lamadzi
Chiwerengero cha mapiritsi omwe adatengedwa amatha kuwerengera payekha, kutengera kuti imodzi imafunikira pa 10 kg yolemera. The chifukwa gawo akhoza kugawidwa 2 waukulu. Amaphwanyidwa kukhala fumbi lamadzimadzi, odzazidwa ndi madzi ochepa kutentha kwa chipinda ndikuledzera 1 ora asanadye. Malasha amamanga ma asidi a bile, samalola kuti mafuta azimbidwa ndi kuwachotsa m'thupi. Nthawi yomweyo, imatha kuchotsa mavitamini, mchere, mahomoni, ndikupangitsa kuchepa. Chifukwa chake, kwa nthawi yayitali sakuvomereza.
Izi ziyenera kukumbukiridwa kwa iwo omwe amamwa mankhwala ena: osachepera ola limodzi ayenera kudutsa pakati pawo ndikuyamba kugwiritsa ntchito kaboni. Zitha kuyambitsa:
M'pofunika kuganizira musanayambe zakudya zamafuta kuti muchepetse kunenepa pa kaboni yoyambitsa. Simungatenge ndi zilonda zam'mimba. Ndipo koposa zonse - sayenera kudzipereka okha.
Mutha kuwona cholesterol yokwezeka popereka magazi kuchokera m'mitsempha pamimba yopanda kanthu kuti mumvetsetse zamankhwala osokoneza bongo. Malinga ndi zotsatira zake, adotolo adzalemberatu chithandizo cha munthu, mwina champhamvu komanso chodwala chomwe chimapangidwira kuti athane ndi matenda a atherosulinosis, ndikulimbikitsa kudya ndi kuchita masewera olimbitsa thupi, omwe kuphatikiza kwake kumachepetsa kuchuluka kwa zinthu zovulaza.
Katundu wa mankhwala osokoneza bongo
Mapiritsi akuda a kaboni yokhazikitsidwa akhala akudziwika ndi kudziwika kwa aliyense. Ichi ndi gawo limodzi la zida zothandizira, zoyenda kapena zoyendera.
Kukonzekera uku ndi kaboni ya amorphous yoyendetsedwa ndi chithandizo chapadera. Ili ndi kapangidwe ka porous ndipo imachokera mu 15 mpaka 97,5%.
Yoyambitsa kaboni ndi sorbent. Izi zikufotokozera zake zothandiza. Iye, monga amatsenga onse, amatha kuyamwa ndikusunga zinthu zovulaza, kuteteza kulowa kwawo kudzera m'matumbo am'mimba. Chifukwa cha kusasinthasintha kwa mankhwalawa, mankhwalawa amakhala ndi mphamvu kwambiri.
Zizindikiro zamagwiritsidwe ntchito ake zimaphatikizidwanso ndi izi zomwe zimapangidwira kaboni.
Mankhwalawa amatha kuthetseratu zizindikiro ndi zovuta za kuledzera, mwachitsanzo, poyizoni wazakudya.
- Carbon activated ndi mankhwala abwino kwambiri. Amachotsa ziphe ndi poizoni kuchokera m'matumbo am'mimba, poletsa kulowetsedwa kwawo mthupi. Kugwiritsa ntchito poyizoni wa zakumwa zoledzeretsa, mankhwala osokoneza bongo, komanso poyizoni wokhala ndi poizoni wazomera ndi mankhwala, kuphatikiza hydrocyanic acid ndi phenol.
- Ndikulimbikitsidwa kuti mugwiritse ntchito limodzi ndi mankhwala ena a viral ndi matenda opatsirana, mwachitsanzo, kolera, typhoid fever, kamwazi.
- Imakhala ndi chothandiza pa matenda ena am'mimba thirakiti: colitis, gastritis, kutsegula m'mimba.
Monga mukuwonera, mankhwalawa ndiofunikira komanso othandiza. Komabe, paliponse palamulo sipamanena kuti momwe makala amathandizira polimbana ndi cholesterol. Komabe, pali lingaliro kuti ndi cholesterol yayitali mankhwalawa ndi othandiza kwambiri. Tiyeni tiyesetse kudziwa kuti malingaliro otere ndi otani.
Limagwirira ntchito ya chinthu
Ndizodziwikiratu kuti kukonzanso kaboni, kulowa mthupi, kumatenga zinthu zosiyanasiyana, kuzisunga ndikumazichotsa m'thupi. Akuti amatha kugwira ma cell a cholesterol, kuwagwira ndikuwachotsa m'thupi. Panali asayansi omwe anachita maphunziro ena. Odwala omwe ali ndi cholesterol yambiri kwa milungu 4 katatu patsiku amatenga makala ake (tsiku lililonse - 8 g). Zotsatira zake ndizosangalatsa, cholesterol mwa odwalawa idatsika ndi 41%.
Komabe, panali okayikira omwe amakhulupirira kuti anthu amangotsatira nthano yatsopano - yodziyambitsa kaboni, ndikuwona kuti ndi vuto pakulimbana ndi matenda ambiri - onenepa kwambiri, cholesterol, ndi zina zambiri. Nthawi yomweyo, odwala amakana mankhwala othandiza komanso amangoipitsa thupi.
Ngakhale zili choncho, kaboni yokhazikitsidwa ndi yothandiza kwambiri chifukwa imachotsa poizoni ndi zinthu zoopsa m'thupi, zomwe zimayeretsa magazi. Chifukwa cha maphunziro a kaboni oyambitsa, kusintha kwa thanzi kumawonedwa.
Momwe angatenge
Kuchuluka kwa mafuta ophatikizidwa ndi cholesterol ndi 8 g patsiku, mu 3 Mlingo wogawika, kwa masabata 2-4.
Kuwerengera molondola kwambiri kumaperekedwanso - piritsi 1 pa 10 kg ya kulemera kwa tsiku. Maphunzirowa ali osachepera milungu iwiri.
Tiyenera kukumbukira kuti kaboni yoyambitsa imakhala ndi zotsutsana:
- Zilonda zam'mimba kapena duodenum,
- Minyewa yam'mimba kapena m'mimba.
Mukamamwa mankhwalawa, ayenera kusamalidwa pazifukwa zina:
- Carbon activated imatenga zonse: zonse zoyipa ndi zothandiza. Ngati mumwa mankhwalawa nthawi yomweyo monga mankhwala ena, pamakhala chiopsezo kuti mankhwalawa sangakhale ndi chidwi chomwe angafune, popeza kaboni yokhoma sangawalole kulowa mthupi. Chifukwa chake, ndikofunikira kuti mupange nthawi yotalikirana pakati pa kugwiritsa ntchito makala ndi makala ena.
- Zomwezi zimapezekanso ndi mavitamini. Kukhazikika kosaloledwa kwa kaboni yoyambitsa kungayambitse hypovitaminosis.
- Kugwiritsira ntchito nthawi yayitali makala ochulukitsidwa kumatha kubweretsa zovuta m'mimba komanso kusokonezeka kwa metabolic.
Tsopano tikudziwa mphamvu ya mpweya woyambitsa pa cholesterol. Tikudziwanso kuti pachilichonse muyenera kudziwa muyezo ndi kusamalira thupi lanu. Kokha kufikira pankhani zaumoyo modekha komanso zomveka ndi komwe munthu angapeze zotsatira.
Mfundo yogwira ntchito
Makala ophatikizidwa ndi njira yabwino yokwanira yomwe imachotsa poizoni ndi poizoni womwe umalowa ziwalo za m'mimba. Ndiwothandiza makamaka kwa anthu omwe adamwa mowa, mankhwala osokoneza bongo kapena hydrocyanic acid. Enterosorbent imagwirizanitsidwa ndi cholesterol. Kuphatikizika kwa kuchuluka kwa mowa wa lipophilic mu plasma ndi kowopsa pakukula kwa stroko kapena necrosis ya maselo a myocardial.
Chiphuphu chokhala ndi porous pamwamba chimatsitsa cholesterol yayikulu m'mwazi mwa kugwira tinthu tawo ndi kuichotsa kunjako.
Ndikofunika kuyamba kuchiza matenda a hypercholesterolemia munthawi yake, pogwiritsa ntchito njira yogwiritsa ntchito njira yogwiritsa ntchito mafuta (corbent) ndikuyambitsa njira zina zomwe zimathandizira kuti pakhale mafuta ambiri. Komabe, mu malangizo a mankhwalawo, palibe pomwe amatchulapo za cholesterol, musanayigwiritse ntchito, muyenera kufunsa dokotala yemwe angakupatseni mankhwala othandizira, omwe ali ndi nthawi yayitali, komanso kuti adziwe nthawi yayitali yothandizira.
Kodi imakhazikitsidwa liti?
Ndikofunika kugwiritsa ntchito kaboni yokhazikitsidwa pomwe mankhwala opangira mankhwala, zakudya zamafuta ochepa, mankhwala, ndi mafutulo amitundu yambiri alowa mthupi la zinthu zoopsa. Sorbent imaphatikizidwa ndi chithandizo chovuta cha flatulence, matenda am'mimba osiyanasiyana a etiologies ndi matumbo colic. Kuti mukwaniritse bwino, muyenera kuyamba kumwa mankhwalawo mwachangu momwe mungathere.
Momwe mungatenge ndikuvulaza
Madotolo adatha kutsimikizira kuti makala omwe adalowetsedwa amatha kutsitsa cholesterol "yoyipa" yambiri m'madzi a m'magazi. Koma kuti kuchepa kwa mafuta onga ngati mafuta sikutenga nthawi yayitali, ndikofunikira kumwa sorbent molondola, kutsatira mosamalitsa malangizo a dokotala. Mankhwalawa amayeretsa magazi m'mimba ndi magazi ku poizoni ndi zinthu zovulaza, achulukitse kuthamanga kwa magazi ndikuwongolera magazi, ndipo nthawi yomweyo amachepetsa cholesterol yambiri ndikuchotsa chiwopsezo cha thrombophlebitis. Koma kuti mukwaniritse izi, muyenera kumwa mapiritsi akuda potengera 10 kg ya kulemera kwa thupi la munthu - 0,25 mg ya mankhwalawa. Kuchuluka kwa mapiritsi kuyenera kugawidwa mu 2 Mlingo - m'mawa ndi nthawi yogona, mphindi 120 musanadye, osambitsidwa ndi madzi oyeretsedwa. Nthawi zambiri, kuti muchepetse cholesterol, chinthu chakuda cham'mimba chimadyedwa kwa masabata awiri.
Kuti achepetse kuchuluka kwa zakumwa zachilengedwe za lipophilic, njira yotsatsira kaboni yomwe inakonzedwa molingana ndi izi:
Mowa wambiri wa lipophilic ukhoza kuchotsedwa m'thupi pogwiritsa ntchito njira yothirira yamadzi.
- Werengani nambala yofunikira ya mapiritsi ndi kuwapera kukhala ufa.
- Tengani theka la mankhwala osweka ndikutsanulira madzi ofunda.
- Imwani mphindi 60 musanadye.
Sorbent imatsitsa cholesterol yangwiro, koma imapikisidwa kuti muigwiritse ntchito kwa nthawi yayitali. Kuphatikiza pa kutsitsa mafuta, imathandizanso kuchepetsa kuchuluka kwa mahomoni, mavitamini ndi michere, ndikupangitsa kuti ikhale yoperewera m'thupi la munthu. Popewa zovuta zosagwiritsidwa ntchito ndi sorbent, musapitirire 8 g patsiku ndikugwiritsa ntchito kwa masiku osapitilira 30.
Ndani adzapweteke?
Kugwiritsa ntchito makala opangidwa ndi mafuta ambiri, sikuti aliyense ndiololedwa. Mankhwala amalowa m'matumbo, chifukwa chake, sayenera kugwiritsidwa ntchito ndi odwala omwe ali ndi zilonda zam'mimba komanso gawo loyambirira la matumbo ochepa. Matendawa ndi oopsa ngati magazi atayamwa atayikiridwa. Komanso, mankhwalawa amaphatikizidwa chifukwa cha hypersensitivity pazinthu zake komanso mukamagwiritsa ntchito mankhwala osokoneza bongo.
Chenjezo ndi kuyenderana ndi mankhwala
Kugwiritsa ntchito makala olimbana ndi cholesterol, mawonekedwe ena a mankhwala omwe ali ndi mankhwalawa ayenera kuganiziridwanso. Chifukwa chake, ma sorbent adsorbes ndi zofunikira, mwachitsanzo, mavitamini. Sitikulimbikitsidwa kuphatikiza mankhwalawa ndi mankhwala ena, popeza pali ngozi yoti sangakhale ndi chithandizo chamankhwala chofunikira. Poterepa, muyenera kuwonetsetsa magawikidwe apakati pazilandira zamankhwala. Ngati mumagwiritsa ntchito mapiritsi akuda, metabolism yanu imasokonezeka, ndipo padzakhala zovuta ndi kugaya chakudya.
Alumali moyo wotsekedwa wokhazikitsa mankhwala ndi zaka 2. Ngati mapiritsi akakumana ndi mpweya, ndiye kuti nthawi yawo yosungirako imachepetsedwa mpaka miyezi isanu ndi umodzi. Tsiku lasonyezedwa pamaphukusi, kaboni yokhazikitsidwa siyabwino kuti ingavomerezedwe, sichingavulaze, koma simuyenera kuyembekezera phindu kuchokera pamenepo. Mankhwalawa sayenera kukhudzidwa ndi kuwala kwa dzuwa, chinyezi, mpweya wotentha ndipo ana ang'ono sayenera kupeza.
Zotsatira za pharmacological
Carbon activated imakhala ndi adsorasing, detoxifying, antidiarrheal effect. Imagwiritsidwa ntchito ngati sorbent pakuledzera, pomwe:
- poyizoni wa chakudya ndi mowa,
- mankhwala osokoneza bongo - barbiturates, aminophylline, glutethimide,
- poyizoni ndi zoopsa za chomera ndi mankhwala - hydrocyanic acid, phenol.
Mankhwala amaphatikizidwa ndi zovuta kuthandizira matenda opatsirana - kamwazi, kolera, typhoid. Ndiofotokozedwanso m'matenda am'mimba omwe amatayikira - kutsegula m'mimba, gastritis, colitis, komanso matenda a shuga, kulephera kwaimpso, ndi khungu.
Sorbent imagwiritsidwa ntchito mumapulogalamu oyesera kuyeretsa thupi (kufalikira kwa magazi, njira ya m'mimba). Mankhwala amateteza kuthamanga kwa magazi, kusintha magazi, kumachepetsa chiopsezo cha thrombosis.
Thupi limachita zinthu ngati zosefera, zomwe:
- imatenga poizoni, mchere wa zitsulo zolemera, mipweya, barbiturates,
- amaletsa kuyamwa kwawo m'mimba,
- amalimbikitsa chimbudzi pochulukitsa,
- sichimakwiyitsa nembanemba.
Ngakhale kuli ndi katundu wotsatsa malonda, malangizowo alibe zambiri zokhudzana ndi kuthekera kofotokozera mpweya wodziyambitsa ndi cholesterol yambiri.
Kafukufuku adatsimikiza kuti tinthu tomwe timatulutsa za sorbent timamanga bile acid (zomwe zimachokera ku cholesterol) ndikuzichotsa mwachilengedwe. Mwanjira imeneyi, malasha amalepheretsa kuyamwa kwa zotuluka zam'mimba - mafuta kuchokera ku chakudya. Katunduyu amalola kugwiritsa ntchito mankhwalawa pochiza hypercholesterolemia.
Koma kuphatikiza ndi mafuta, kumangiriza michere, michere yogwiritsira ntchito yachilengedwe yomwe zakudya zimakhala. Ndi chithandizo chakanthawi, poyerekeza ndi kuchepa kwa mafuta m'thupi, zotsatira zosafunikira zitha kuwonedwa - kuchepa kwa vitamini, kuchepa kwa mchere, kusowa kwa michere.
Zambiri za dosing ndi hypercholesterolemia
Pamsika wamankhwala, kaboni yokhazikitsidwa imaperekedwa ngati mapiritsi akuda ozungulira a pakamwa, zomwe zimapangitsa kuti pakhale mlingo wabwino. Ndi cholesterol yokwezeka, mlingo wa tsiku ndi tsiku wa munthu wapakati amakhala pafupifupi magalamu 8 (mapiritsi 32). Piritsi lililonse limakhala ndi 0,25 g yogwiritsira ntchito pophika.
Zambiri za Microscopic zimawonetsa kuti kudya kwa 8 g tsiku lililonse kwa mpweya wabwino kumathandizira kusintha kwa maselo okhudzana ndi msinkhu, kusintha kwa zotupa m'matumbo a coronary, ndi mtima minyewa ya dystrophy.
Koma poganizira mawonekedwe osiyanasiyana a malamulo oyendetsera thupi, molondola kwambiri, mawonekedwewo amawerengedwa payekhapayekha. Nthawi zambiri, 10 kg iliyonse yakulemera imafanana ndi piritsi limodzi. Chifukwa chake, kwa wodwala wolemera makilogalamu 50, mlingo wa tsiku ndi tsiku udzakhala mapiritsi 15 (zidutswa 5 pa mlingo), komanso kwa wodwala yemwe kulemera kwake kuli pafupifupi 80 makilogalamu, 24 mapiritsi (zidutswa 8 pa mlingo).
Mapiritsiwo amaphwanyidwa mpaka kukhala ufa, wodzazidwa ndi madzi ofunda. Madzi samasungunula malasha, koma amathandizira pakumeza. Osakaniza aledzera 1-2 maola asanadye.
Njira yomwe ili pamwambapa imabwerezedwa tsiku lililonse kwa masiku 28. Panthawi imeneyi, kuchepa kwamankhwala kumatheka. Poganizira za chiwopsezo ichi, akatswiri ena amalimbikitsa kuchepetsa mankhwalawa mpaka masiku 14. Maphunzirowa akhoza kuyambiranso pambuyo popuma miyezi iwiri.
Kutenga makala ochulukitsidwa kuchokera ku cholesterol yambiri nthawi imodzi ndi mankhwala ena osavomerezeka. Adsorbent imatha kusokoneza kuyamwa kwa zinthu zomwe zimagwira, mwakutero kuchepetsa kwambiri achire zotsatira za mankhwalawa. Popewa kuletsa kugwiritsa ntchito mankhwala othandizira, mapiritsi ayenera kumwedwa patadutsa maola awiri musanamwe mankhwala ena.
Chithandizo cha Carbon Hypercholesterolemia: Yabodza kapena Umboni
Mphamvu ya adsorbent yokhala ndi cholesterol yambiri imatsimikiziridwa ndi kafukufuku wapadziko lonse wamankhwala:
- Magazini yaku Britain ya The Lancet (Ogasiti, 1986) inafalitsa zotsatira zochititsa chidwi kuchokera ku kafukufuku wapamwamba. Odwala omwe ali ndi hypercholesterolemia kwa masiku 8 adatenga 8 g ya makala okhazikika (pafupifupi supuni ziwiri). Kumapeto kwa chithandizo, zotsatira za mbiri ya lipid zinali zodabwitsa: kuchuluka kwa cholesterol kwathunthu m'magazi a odwala kumatsika ndi 25%, pomwe kuchuluka kwa lipoproteins otsika kwambiri (LDL) kutsika ndi 41%, ndipo kuchuluka kwa magawo abwino a cholesterol (HDL / LDL) kuwirikiza.
- Magazini a Kidney International Supplement Magazine (Juni, 1978) adasindikiza zidziwitso zokhoza kukhazikitsa kaboni kutsika plasma triglycerides. Odwala omwe ali ndi cholesterol yayikulu kwambiri, kuchuluka kwa mankhwala amenewa kumachepera ndi 76%.
- European Journal of Clinical Pharmacology (1989) inafalitsa zotsatira za kafukufuku wochitidwa ndi asayansi ochokera ku yunivesite ya Helsinki. Omwe anayeserera kwa milungu itatu adatenga chinangwa ndikuyambitsa kaboni mosiyanasiyana - 4, 8, 16, komanso 32 g / tsiku. Mbiri ya lipid idawonetsa zotsatira zodalira mlingo: kuchuluka kwa cholesterol kwathunthu, komanso zigawo zoyipa za lipoproteins, zimatsika kuchoka pa 29 mpaka 41% molingana ndi mlingo wa makala omwe adalowetsedwa ndi mutu uliwonse.
Magazini yomwe tatchulayi idaperekanso owerenga zotsatira za kafukufuku wokhudzana ndi izi yemwe amawunikira zotsatira za makala okhazikika ndi Cholesterol (Kolesteramin), mankhwala omwe amagwiritsidwa ntchito ndi mankhwala achizungu pochiza hypercholesterolemia.
Pamene malasha adatengedwa, cholesterol yathunthu idatsika ndi 23%, LDL - ndi 29%. Odwala omwe amathandizidwa ndi Colesteramin, kuchuluka kwa cholesterol yotsika ndi 31%, lipoproteins zovulaza - ndi 39%. Ndi kuphatikiza kwa mankhwala awiri, kuchepa kwa 30 ndi 38%, motsatana. M'magulu onse atatu, zotsatira zomwezo zidawonedwa. Asayansi adaona kuti zochita za sorbent ndizofanana ndi zomwe zimachitika ndi mankhwala apadera.
Ngakhale zotsatira zosatsimikizika za kafukufukuyu, akatswiri ena akukhulupirira kuti kuchepa kwa mafuta a cholesterol chifukwa chogwiritsa ntchito malasha kumayenderana ndi vuto la placebo, lomwe limagwira ntchito mwa anthu omwe amakhulupirira kwambiri machiritso.
Contraindication
Mankhwala otetezeka akadali achilendo kwa thupi. Mndandanda wamilandu yolandila:
- kusalolera payekha pazinthu zake,
- zilonda zam'mimba zam'mimba ndi duodenum,
- zilonda zam'mimba,
- m'mimba,
- atom yamatumbo,
- kuchepa kwa mavitamini, hypovitaminoses,
- ntchito yothandizanso ogwiritsa ntchito ma detoxifying.
Masiku ano, makampani opanga zamankhwala amapereka mankhwala othandiza kwambiri amtunduwu. Enterosgel, Atoxil, Polysorb, malasha oyera, Smecta - mankhwalawa amalimbana ndi kuchotsedwa kwamafuta a cholesterol koyipanso, ali ndi mndandanda wawung'ono wotsutsa, ndiwosavuta kugwiritsa ntchito.
Zotsatira zoyipa
Pazomwe zimagwiritsidwa ntchito kwakanthawi kochepa, malasha amavomerezedwa bwino ndi odwala. Kuchiza kwa nthawi yayitali kumatha kuyambitsa zovuta zina, kuphatikizapo:
- Kuchokera kugaya chakudya - nseru, kusanza, kudzimbidwa, kutentha kwa mtima, kutsegula m'mimba, kudzimbidwa,
- ambiri kagayidwe kachakudya matenda - malabsorption azinthu yogwira, mavitamini, mchere,
- kuchepa kwa matenda a shuga m'magazi, hemorrhage, hypoglycemia, hypothermia,
- thupi lawo siligwirizana, kutsitsa magazi.
Kuchepa kwa zizindikirozi pamwambapa kumawonjezeka molingana ndi kuchuluka kwa mankhwalawa. Kugwiritsa ntchito malasha nthawi yayitali kapena kuwotcha kwina kulikonse ndi koopsa pamavuto amchere, michere, lipid, mapuloteni.
Masiku ano, funso loti kuthekera kochizira hypercholesterolemia ndi kaboni yokhazikitsidwa ndi lotseguka. Komabe, ofufuza ambiri, potengera ziwerengero zomwe zapezeka, amalimbikitsa mankhwalawa kwa anthu omwe ali ndi cholesterol yayikulu.
Zinthu zomwe zidakonzedwa ndi olemba polojekitiyi
malingana ndi ndondomeko yakusinthaku.