Mapiritsi a Lozap Plus (12

Mankhwala "Lozap" (Lozap) amapezeka m'mapiritsi otsekemera, mu mitundu yosiyanasiyana kuchokera ku 12.5 mn (No. 90) mpaka 50 mg (No. 50, No. 30). Komanso mankhwalawa "Lozap kuphatikiza" nawonso ali m'gululi. Amasiyana ndi "Lozap" popanga. Chifukwa chake, mu "Lozap" pali chinthu chimodzi chogwira - losartan potaziyamu, ndipo mu "Lozap kuphatikiza" - ziwiri: losartan potaziyamu ndi hydrochlorothiazide. Monga zinthu zowonjezera, mannitol, microcrystalline cellulose, croscarmellose sodium, magnesium stearate, povidone, macrogol, dimethicone, hypromellose, talc, utoto wachikasu amagwiritsidwa ntchito pokonzekera.

Zotsatira za pharmacological

"Lozap" "ndi antihypertensive othandizira omwe amalepheretsa maselo a AT1 subtype receptors ndikusokoneza kumangiriza kwa angiotensin 2 ndi receptors a AT1. Mankhwalawa sasokoneza dongosolo la kinin, samathandizira pakukula kwa bradykinin. Lozap ndi mankhwala osokoneza bongo. Yake yogwira metabolite (carboxylic acid), yomwe imapangidwa mu biotransfform, imakhala ndi antihypertensive. Mukamamwa ola limodzi, "Lozap" imafika m'magazi am'magazi ambiri; Mankhwalawa amachotsedwa pakatha maola asanu ndi anayi. Mu maola awiri oyamba, losartan imachotsedwa, ndipo metabolite yake yogwira - kwa maola 9. Monga momwe adadziwitsira pakufufuza kwazachipatala, mphamvu ya antihypertensive imatheka mwachangu limodzi ndi losartan ndi hydrochlorothiazide. Chifukwa chake, mankhwala ophatikiza "Lozap kuphatikiza" amalimbana bwino ndi vuto lomwe limayambitsa.

Mlingo umodzi wa Lozap uli ndi antihypertensive kwa maola 6, pambuyo pake zotsatira zimachepa pang'onopang'ono tsiku limodzi. Chifukwa chake, muyenera kugwiritsa ntchito "Lozap" pafupipafupi. Ndi wokhazikika kuperekera mankhwala mu wachiwiri kapena wachinayi, wodwalayo amamva mphamvu zonse za antihypertensive mankhwala. Kupsinjika kwa magazi kumakhala koyenera. Tiyenera kudziwa kuti kuchepa kwa kuthamanga kwa magazi kumawonedwa chimodzimodzi mwa amuna ndi akazi. Kuyanjana kwamtundu wa anthu mu ndondomeko ya antihypertensive, yomwe idafotokozedwa pakufufuza, sikunawonekere pokwaniritsa zotsatira zabwino. "Lozap" imachitanso chimodzimodzi kwa aliyense.

Zizindikiro zogwiritsidwa ntchito

Lozap imaperekedwa kwa odwala omwe ali ndi matenda oopsa, komanso kuphatikiza mankhwalawa - kwa odwala omwe ali ndi vuto la mtima osalephera kapena osagwiritsa ntchito bwino mankhwala pogwiritsa ntchito ACE zoletsa. Mankhwala tikulimbikitsidwa kupewa matenda a mtima, kuphatikizapo sitiroko, ndi kufa mwa anthu omwe ali ndi kuthamanga kwa magazi ndi kumanzere kwamitsempha yamagazi. Matenda a shuga a nephropathy odwala matenda ashuga, ogwirizana ndi matenda oopsa, amathandizidwanso mothandizidwa ndi "Lozap".

Mlingo ndi makonzedwe

Pankhani ya matenda oopsa, "Lozap" amaikidwa kamodzi patsiku muyezo wa 50 mg. Ngati vutoli silikwaniritsidwa, mulingo woyenera uyenera kuchulukitsidwa: 100 mg kamodzi patsiku kapena 50 mg 2 kawiri pa tsiku.

Chithandizo cha matenda a mtima osakhazikika ayenera kuyamba ndi 12,5 mg patsiku, kamodzi. Pakupita sabata limodzi, mlingo umayamba kuchuluka mpaka 25 mg, kenako 50 mg. Pankhaniyi, ndikofunikira kuwunika momwe wodwalayo alili, kulekerera kwake mankhwala.

Kwa odwala omwe akutenga kuchuluka kwa okodzetsa, muyeso woyamba wa mankhwalawa ndi 25 mg. Pang'onopang'ono, mlingo umatha kuchuluka. Kwa okalamba ndi odwala omwe ali ndi vuto la aimpso, mlingo wa mankhwalawa sasinthidwa. Kuchepetsa Mlingo ndikofunikira kwa anthu omwe ali ndi vuto la chiwindi.

"Lozap" imatengedwa kamodzi (kapena kawiri patsiku), osafuna kutafuna piritsi ndikumwa madzi ambiri. Mutha kumwa mankhwalawa nthawi iliyonse, mosasamala chakudya.

Zotsatira zoyipa

Pa ntchito "Lozap", thupi lawo siligwirizana, redness pakhungu, urticaria, anaphylactic mantha, nosebleeds, arrhythmias, angina pectoris, myocardial infarction, vasculitis, kuchepa magazi, kupweteka kwa msana, mutu, hypotension, vasculitis, chiwindi kukomoka, myalgia. kupukusa pakamwa, kusanza, kudzimbidwa, kugona, nkhawa, kusowa tulo, kusokonezeka tulo, kukomoka, migraine Nthawi zina, kulawa kwamkati ndi kuwona, kutsika libido, kusabala.

Kuchita ndi mankhwala ena

Pogwiritsa ntchito munthawi yomweyo "Lozap", "Rifampicin" kapena "Fluconazole", plasma level ya metabolite yogwira ikhoza kuchepa. Mukamagwiritsa ntchito mankhwala okhala ndi potaziyamu ochepa okodzetsa, mankhwala a potaziyamu, kuwongolera kwa potaziyamu ndikofunikira. Chepetsani zotsatira zamphamvu za mankhwala a "Lozap" monga "Indomethacin" ndi ena a NSAID. Panalibe kuchepa kwenikweni pobwera ndi digoxin, phenobarbital, warfarin, erythromycin ndi cimetidine.

Zowonjezera

Kugwiritsa ntchito mankhwalawa sikuloledwa kwa anthu omwe akudwala matenda a chiwindi. Ngati ndi kotheka, gwiritsani ntchito mankhwalawa kuti muchepetse muyezo ndikuwunika momwe wodwalayo alili.

Mankhwalawa amatha kubweretsa kugona, kusokoneza komanso kuwongolera kuyendetsa galimoto ndi zovuta, kotero sikulimbikitsidwa kuti izipatsidwe kwa anthu omwe ntchito zawo zimagwirizanitsidwa ndi chidwi chochulukirapo.

Ngakhale kumwa mankhwalawa, kumwa mowa ndikoletsedwa.

Kutulutsa mawonekedwe ndi kapangidwe kake

Mankhwala a Lozap, zomwe zikuwonetsa kugwiritsa ntchito zomwe zidzafotokozeredwe pansipa, ali ndi mawonekedwe ake:

• Mapiritsi a 12.5 mg amtundu woyera kapena wa kirimu, wokulirapo, wamtundu wa filimu mu chipolopolo.
• Mapiritsi a 50 mg oyera kapena kirimu zonona, okwera, mu chipolopolo chokhala ndi notch yosavuta kugawanika.
• Mapiritsi a 100 mg oyera kapena kirimu zonona, okwera, mu chipolopolo, ndi notch kuti asinthe mlingo.

Chosakaniza chophatikizika ndi potaziyamu losartan ndi zina zowonjezera zomwe mulibe achire. Chipolopolocho chimakhala ndi leyphilus yoyera, hypromellose, macrogol, MCC ndi titanium dioxide.

Mankhwala

Losartan ndi mdani wina wa angiotensin II receptors (subtype AT1), yemwe amachititsa bradykinin ndipo saletsa enzyme ya kinase II. Imachepetsa OPSS (zotumphukira zamitsempha yathunthu), kuchuluka kwa aldosterone ndi adrenaline m'magazi, kuthamanga kwa magazi (kuthamanga kwa magazi), kuthinikizidwa mu ziwiya zamagazi. Zimalepheretsa kuwoneka kwa myocardial hypertrophy, zimathandizira kulolerana kwa odwala omwe ali ndi vuto la mtima (aakulu mtima kulephera).

Hydrochlorothiazide - thiazide okodzetsa amalepheretsa kuyambiranso kwa ayoni a sodium, kumawonjezera kuphipha kwa bicarbonate, potaziyamu ion ndi phosphates mu mkodzo. Amachepetsa kuthamanga kwa magazi chifukwa kuchepa kwa bcc (kuzungulira magazi), kuponderezera mphamvu ya vasoconstrictors, kusintha kosinthika kwa khoma lamitsempha komanso kuwonjezeka kwa kuletsa kwa ganglia.

Contraindication

Contraindication chithandizo ndi motere:

• anuria
• mimba
• nthawi yoyamwitsa,
• zaka mpaka 18 - (kuchita bwino ndi chitetezo sizinakhazikitsidwe),
• mankhwala othana ndi hypokalemia kapena hypercalcemia,
• kukanika kwambiri kwa chiwindi,
• Matenda oletsa kupezeka m'mimba,
• Hyponatremia
• Hyperuricemia ndi / kapena gout,
• kukanika kwa aimpso (CC ≤ 30 ml / min),
• Hypersensitivity pazinthu zilizonse za mankhwala kapena mankhwala ena omwe amapezeka ndi sulfonylamide.

Amalembedwa mosamala kwa odwala omwe ali ndi vuto la impso kwamitsempha kapena stenosis yamitsempha yama impso imodzi, machitidwe a hypovolemic (kuphatikizapo kutsekula m'mimba, kusanza), hyponatremia (chiwopsezo chowonjezeka cha matenda ochepa) kwa odwala omwe ali ndi mchere wochepa kapena wopanda mchere, hypochloremic alkalosis, hypomagnes , omwe ali ndi matenda ophatikizika a minofu (kuphatikizapo SLE), odwala omwe ali ndi vuto la chiwindi kapena omwe akudwala matenda a chiwindi, a shuga, a mphumu ya bronchial (kuphatikizapo mbiri), mbiri yakutali, munthawi yomweyo ndi NSAIDs, incl. COX-2 inhibitors, komanso oimira mpikisano wa Negroid.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Zambiri zokhudzana ndi kutenga Lozap Plus panthawi yapakati sizikupezeka, koma zimadziwika kuti mankhwalawa omwe amakhudza dongosolo la renin-angiotensin mu 2nd ndi 3 trimester ya mimba imatha kudzetsa vuto la kukula komanso ngakhale kufa kwa fetal.

Pachifukwa ichi, tikulimbikitsidwa kuti musiye kumwa mankhwalawa nthawi yomweyo mukakhala ndi pakati.

Ndi kuyamwitsa, muyenera kusiya kapena kusiya kulandira chithandizo.

Mlingo ndi njira yoyendetsera

Malangizo ogwiritsira ntchito akuwonetsa kuti Lozap kuphatikiza amatengedwa pakamwa, mosasamala kanthu za kudya.

1. Ndi nkhawa yochulukirapo (matenda oopsa), mlingo woyenera ndi woyamba ndimapiritsi 1 / tsiku. Ngati mukugwiritsa ntchito mankhwalawa muyezo, sizingatheke kukwaniritsa kuthamanga kwa magazi, mlingo wa mankhwala a Lozap Plus utha kuwonjezereka ku mapiritsi a 2. 1 nthawi / tsiku
2. Mlingo waukulu ndi mapiritsi awiri. 1 nthawi / tsiku Pazonse, kufalikira kwakukulu kumachitika mkati mwa masabata atatu atayamba chithandizo.
3. Palibe chifukwa chosankhidwa mwapadera kwa odwala ake okalamba.

Pofuna kuchepetsa chiopsezo chokhala ndi matenda amtima komanso kufa kwa odwala omwe ali ndi matenda oopsa ndipo amasiya zamitsempha yamagazi, losartan (Lozap) amamuika muyezo woyambirira wa 50 mg / tsiku. Odwala omwe alephera kukwaniritsa kuchuluka kwa kuthamanga kwa magazi pomwe akugwiritsa ntchito losartan pa 50 mg / tsiku amafunikira chithandizo ndi kuphatikiza kwa losartan ndi hydrochlorothiazide muyezo wotsika (12.5 mg), womwe umatsimikiziridwa ndi kukhazikitsidwa kwa mankhwala Lozap Plus.

Ngati ndi kotheka, mlingo wa Lozap Plus ungakulitsidwe kumapiritsi 2. (100 mg ya losartan ndi 25 mg ya hydrochlorothiazide) 1 nthawi / tsiku.

Zotsatira zoyipa

Kuyesedwa kwa mayesero azachipatala pakuwathandiza kuphatikiza matenda oopsa ndi losartan ndi hydrochlorothiazide osakanikirana adawonetsa kukulira koyipa komwe kumachitika pafupipafupi 1% kapena kuposanso poyerekeza ndi chizungulire. Zotsatira zoyipa zomwe zimanenedwa panthawi yophatikizira mankhwala ndi losartan ndi hydrochlorothiazide kuchokera ku kachitidwe ndi ziwalo:

• chiwindi ndi biliary thirakiti: kawirikawiri - chiwindi,
• mantha dongosolo: ndi pafupipafupi - dysgeusia,
• zotengera: ndi pafupipafupi pafupipafupi - orthostatic zotsatira, amadalira mlingo,
• khungu ndi subcutaneous minofu: yokhala pafupipafupi - mawonekedwe a khungu of zokhudza zonse lupus erythematosus,
• othandizira ndi a labotale maphunziro: kawirikawiri - ntchito yowonjezera ya hepatic transaminases, hyperkalemia.

Kugwiritsanso ntchito kwa Lozap kuphatikiza kumatha kuyambitsa zovuta zonse zomwe zimagwiritsidwa ntchito ndi mankhwala mosiyana.

Zotsatira zoyipa zomwe zimagwiritsidwa ntchito ndi hydrochlorothiazide:

• ziwalo zamasomphenya: pafupipafupi - xantopsia, kuchepa kwakanthawi kwamawonekedwe owoneka,
• m'mimba thirakiti: pafupipafupi - nseru / kusanza, kudzimbidwa, kutsegula m'mimba, gastritis, cramping, sialadenitis,
• mtima dongosolo: pafupipafupi - khungu vasculitis, necrotic vasculitis,
• khungu ndi subcutaneous minofu: pafupipafupi - urticaria, photosensitivity, poyizoni epermermal necrolysis,
• chiwindi ndi biliary thirakiti: pafupipafupi - kapamba, cholecystitis, cholestatic jaundice,
• kupuma dongosolo, chifuwa ndi zam'mimba ziwalo: pafupipafupi - kupuma nkhawa syndrome (RDS), kuphatikizapo sanali Cardiogenic m`mapapo mwanga edema ndi chibayo,
• magazi ndi zamitsempha yamagazi dongosolo: pafupipafupi - hemolytic anemia, aplastic anemia, leukopenia, thrombocytopenia, phenura, agranulocytosis,
• kagayidwe: pafupipafupi - hypokalemia, hyperuricemia, hyponatremia, hyperglycemia, anorexia,
• chitetezo chamthupi: kawirikawiri - anaphylactic zimachitika kuti zikhumudwitse,
• mitsempha: nthawi zambiri mutu,
• psyche: pafupipafupi - kusowa tulo,
• impso ndi kwamikodzo thirakiti: pafupipafupi - kulephera kwa impso, ma nephritis apakati, glycosuria,
• minofu ndi mafupa am'mimba: minyewa - minofu kukokana,
• zovuta zapakati: pafupipafupi - chizungulire, kutentha thupi.

Zotsatira zoyipa zogwiritsidwa ntchito ndi losartan:

• chitetezo chamthupi: kawirikawiri - kumachitika kwa hypersensitivity, kuphatikizapo anaphylactic zimachitika, angioedema a glottis ndi larynx ndi mwadzidzidzi airway kutsekeka, kutupa kwa nkhope, pharynx, lilime, milomo,
• kumaliseche ndi chithokomiro cha mamina: mochulukirapo - kukokoloka, kuchepa kwa libido,
• chida chamawonedwe: pafupipafupi - mphamvu yowotcha m'maso, kuchepa kwa mawonekedwe owoneka, conjunctivitis, kuwona kwamaso,
• makutu akumva komanso labyrinth: pafupipafupi - vertigo, kulira m'makutu,
• khungu ndi subcutaneous minofu: pafupipafupi - dermatitis, hyperemia, zidzolo, kuyabwa, thukuta, photosensitivity, khungu lowuma, alopecia,
• chiwindi ndi chithokomiro chothandizira: chosasintha pafupipafupi - kulephera kwa chiwindi,
• zovuta zapafupipafupi: pafupipafupi - kupweteka pachifuwa, asthenia, kutopa, kawirikawiri - kutentha thupi, kutupa kwa nkhope, ndi pafupipafupi - kufooka, zizindikiro ngati chimfine,
• m'mimba thirakiti: Nthawi zambiri - kutsegula m'mimba, nseru, kukomoka, kupweteka pamimba, kawirikawiri - kusanza, gastritis, kamwa yowuma, kudzimbidwa, kugonthana, kupweteka kwameno,
• kagayidwe: pafupipafupi - gout, anorexia,
• minofu ndi mafupa owoneka bwino: kawirikawiri - kupweteka kumbuyo, kupweteka kwa mwendo, sciatica, minofu kukokana, osachepera - kupweteka kwa minofu ndi mafupa, kutupa kwa mafupa, kufooka kwa minofu, fibromyalgia, nyamakazi, arthralgia, kuuma kwa mafupa, ndi mafupipafupi osasinthika - rhabdomyolysis,
• psyche: pafupipafupi - kusowa tulo, kusowa - kukumbukira kwa kukumbukira, kukhumudwa, kusokonezeka, kugona tulo, maloto osazolowereka, kugona, mantha, nkhawa, nkhawa,
• kupuma dongosolo, chifuwa ndi pakati:
• magazi ndi zamitsempha yamagazi dongosolo: pafupipafupi - hemolysis, kuchepa magazi, ecchymosis, matenda a Shenlein-Genoch, omwe amakhala ndi pafupipafupi - thrombocytopenia,
• mantha dongosolo: Nthawi zambiri - chizungulire, kupweteka mutu, pafupipafupi - paresthesia, kusakwiya, syncope, migraine, kugwedezeka, zotumphukira neuropathy,
• mtima dongosolo: pafupipafupi - vasculitis, atrioventricular block II degree, angina pectoris, kupweteka kwa sternum, orthostatic hypotension, kuchepa kwa kuthamanga kwa magazi, arrhythmias (tachycardia, sinus bradycardia, yamitsempha yamagazi tachycardia, fibrillation ya atria, cyricular fibrillation, mtima
• impso ndi kwamikodzo thirakiti: Nthawi zambiri - mkhutu aimpso ntchito, pafupipafupi - matenda opatsirana kwamikodzo, peremptory imayitanitsa kukodza, nocturia,
• maphunziro a labotale ndi othandizira: pafupipafupi - hyperkalemia, kuchepa kwakukulu kwa hemoglobin ndi hematocrit, ochepa - kuwonjezeka pang'ono pazinthu za creatinine ndi urea m'magazi am'magazi, osowa kwambiri - kuwonjezeka kwa zochitika za bilirubin ndi hepatic transaminases, ndi pafupipafupi - hyponatremia.

Bongo

Ndi mankhwala osokoneza bongo a Lozap kuphatikiza, zizindikiro zotsatirazi zimawonedwa: chifukwa cha zomwe losartan - bradycardia, tachycardia, kuchepa kwa kuthamanga kwa magazi chifukwa cha zomwe zili ndi hydrochlorothiazide - kuchepa kwa ma elekitiroma ndi kuchepa madzi m'thupi.

Mankhwala osokoneza bongo ndi chizindikiro.Ndikofunikira kusiya kumwa mankhwalawa, muzitsuka m'mimba ndikuchita zinthu zothandiza kubwezeretsanso madzi osakanikirana ndi magetsi. Ndi kuchepa kwambiri kwa magazi, kukonzekera kulowetsedwa kumasonyezedwa. Hemodialysis kuchotsa losartan sikugwira ntchito. Mulingo wa hydrochlorothiazide kuchotsedwa ndi hemodialysis sunakhazikitsidwe.

Malangizo apadera

Odwala omwe ali ndi vuto la angioedema m'mbuyomu ayenera kuthandizidwa mosamala komanso moyang'aniridwa ndi achipatala.

Pankhani ya cirrhosis kapena zolimbitsa thupi ziwopsezo, mankhwala ndi mankhwala ayenera kuyang'aniridwa ndi akatswiri, chifukwa n`zotheka kuchuluka kwa yogwira zigawo zikuluzikulu za mankhwalawa m'magazi am'magazi, zomwe zimapangitsa kuti pakhale zovuta zochulukirapo komanso zovuta zoyipa.

Lozap ndi Lozap kuphatikiza zingayambitse chizungulire, kugona, komanso kukomoka, zomwe zimakhudza kuthekera kwa kayendedwe, motero, motsutsana ndi maziko ogwiritsa ntchito mankhwalawa, tikulimbikitsidwa kusiya ntchito zilizonse zomwe zimafunikira chidwi chochulukirapo komanso kuthamanga kwa zomwe zimachitika.

Kuyanjana kwa mankhwala

Chida chimenecho chili ndi katundu wothandizira zochita za mankhwala ena a antihypertensive. Kuwonjezeka kwa zotsatira za osapondereza minofu kumadziwikanso. Kugwiritsa ntchito nthawi yomweyo kwa NSAIDs kumatha kufooketsa zochita za hydrochlorothiazide. Kugwiritsa ntchito Lozap kuphatikiza ndi kukonzekera kwa lithiamu kumawonjezera chiopsezo cha kuledzera. Colestyramine amachepetsa kuyamwa kwa hydrochlorothiazide.

Ndi kugwiritsa ntchito pamodzi kwa Lozap kuphatikiza ndi mankhwala a hypoglycemic, kusintha kwa mankhwalawa kumafunikira.

Tidalemba ndemanga za anthu omwe amamwa mankhwala a Lozap kuphatikiza:

1. Olga Ndinkamwa piritsi limodzi lokha lozap + (lotchulidwa ndi dokotala). Mphindi zisanu zilizonse ndinayamba kuthamangira kuchimbudzi, ndipo nditatha mphindi 20 msana wanga umapweteka (mwachiwonekere, osati msana wanga, koma impso zanga). Ululuwo sukanakhoza ngakhale kugona. Pofika m'mawa. Sindinamwerenso. Koma kuchokera ku Lozap yosavuta palibe chomwe chimapweteka.
2. Valentine Kwa chaka chachinayi ndakhala ndikumwa mankhwala omwe amachepetsa kuthamanga kwa magazi. Poyamba, Enap adatenga, koma kwa iye kudali chifuwa champhamvu. Adotolo adalangiza Lozap. Kuthandizidwa bwino. Kupanikizika kunakhala 120/70. Koma posachedwa ndidayamba kumwa Lozapas + ndipo kupanikizika kudakula kwambiri. Lero adalumphira ku 180/110. Ndimayenera kumwa piritsi yachiwiri, koma Lozap ali kale. Kupanikizika pambuyo pa ola limodzi - 135/87. Kodi pali wina amene akuipiraipira kuchokera ku Lozap +? Kodi chingakhale chiyani?
3. Elena. Mwazi wanga wamagazi umakwera kwambiri kawirikawiri, nthawi zambiri ndikakhala ndi mantha kwambiri. Nthawi yomwe idalumphira mpaka zana limodzi ndi zana limodzi, ndinayimbira foni adokotala (sindimakonda kudzilimbitsa mtima). Dotolo adalangiza "Lozap kuphatikiza," kuti magazi anga akhale ngati ali ndi magazi ochepa, theka lokhalo la mapiritsi linali lokwanira, ndipo kupanikizika kunatsika mwachangu. Tsopano m'malo anga azachipatala mumakhala mapiritsi a Lozap Plus nthawi zonse.
4. Tatyana. Ndinkamwa zinthu zambiri kuchokera kumapanikizidwe ochulukirachulukira, m'zaka zanga 26 ndimakhala ndi 140-150…. Atangondilembera, Lozap adalembedwa, ndinayamba kumwa ... Ndipo zonse zidakutidwa ndi ziphuphu zowopsa, matuza ndi mitundu ina yamapapu. Amuna anga adandiletsa kumwa, nditapita kukagona, ndikakhala ndikungokanda kwa mphindi 20, sindinagone. Ndidasiya kumwa iwo ndipo zonse zidapita. Sindikudziwa kuti ndimwa chiyani tsopano.

Malingaliro a madotolo pa Lozap kuphatikiza amasiyanasiyana. Chifukwa chake, madotolo amawona kuti mankhwalawa ndi abwino ndipo, motero, amangoyankha pokhapokha ngati ali ndi matenda ochepa oopsa. Ndiye kuti, ngati munthu ali ndi matenda oopsa, ndiye kuti Lozap kapena Lozap kuphatikiza ndi othandiza ndipo angagwiritsidwe ntchito bwino pochiritsa kwakanthawi.

Ngati matenda oopsa kwambiri komanso ophatikizana ndi matenda a mtima, ndiye kuti mphamvu ya Lozap ndiyotsika kwambiri. Kuchita kwa mankhwalawa ndikokwanira kwa maola asanu mpaka asanu ndi atatu, chifukwa chomwe anthu amapitanso kumwa mankhwala ena amphamvu, owonjezera. Chifukwa chake, muzochitika zoterezi, sikwachilendo kumwa Lozap, chifukwa muyenera kuyang'ana nthawi yomweyo zamankhwala ena amphamvu kwambiri, mwachitsanzo, beta-blockers.

Zofanana muzochitika zamagulu:

• Blocktran
• Brozaar
• Vasotens,
• Vero-Losartan,
• Zisakar
• Cardomin Sanovel,
• Karzartan
• Cozaar
• Nyanja
• Lozarel
• Losartan
• Losartan potaziyamu,
• Zosangalatsa za Losartan,
• Losartan richter
• Losartan teva
• Lorista
• Losacor
• Presartan
• Renicard.

Musanagwiritse ntchito fanizo, funsani dokotala.

Kuphatikizika, mitundu ndi mawonekedwe a kumasulidwa

Pamsika wamankhwala, pali mitundu iwiri ya mankhwalawa - awa ndi a Lozap ndi Lozap Plus. Mitundu iyi imasiyana chifukwa Lozap imangokhala ndi gawo limodzi lokhazikika, ndipo Lozap Plus ili ndi ziwiri. Kuphatikiza apo, gawo lalikulu lomwe limagwira ntchito ku Lozap ndi Lozap kuphatikiza ndi chimodzimodzi, ndipo chinthu chachiwiri ku Lozap kuphatikiza ndi chowonjezera, chowonjezera cha zoyambira. Munkhaniyi, tikambirana mitundu yonse iwiri ya mankhwalawa, chifukwa ali ndi zotsatira zofananira, akuwonetsedwa kuti azigwiritsidwa ntchito mumikhalidwe yomweyo, etc.

Onse a Lozap ndi Lozap Plus amapezeka mtundu umodzi - izi mapiritsi amkamwa. Lozap monga chophatikiza yogwira muli losartan, ndi Lozap kuphatikiza - losartan ndi hydrochlorothiazide. Dongosolo losartan limalepheretsa angiotensin-kutembenuza enzyme (ACE), ndipo hydrochlorothiazide ndi okodzetsa. Chifukwa chake, losartan amachepetsa kuthamanga kwa magazi ndikuchepetsa katundu pamtima, ndipo hydrochlorothiazide imachotsa madzi ochulukirapo m'thupi, ndikulimbikitsa mphamvu ya chinthu choyamba. Chifukwa chake, kuphatikiza kwa Lozap kumakhala ndi mphamvu kwambiri poyerekeza ndi Lozap, chifukwa mumakhala zinthu zambiri, osati chinthu chimodzi.

Mwakutero, Lozap Plus idapangidwa kuti ikhale yosavuta kugwiritsa ntchito, chifukwa ma diuretics nthawi zambiri amagwiritsidwa ntchito popititsa patsogolo zotsatira ndi ACE inhibitors. Opanga adangophatikiza zinthu izi mu mankhwala amodzi, zomwe zimakhala zosavuta kwa munthu amene ayenera kumwa piritsi limodzi lokha, osati awiri, atatu, etc.

Lozap imapezeka m'malo atatu - 12,5 mg, 50 mg ndi 100 mg ya losartan piritsi. Lozap Plus ikupezeka mu umodzi - 50 mg wa losartan + 12,5 mg wa hydrochlorothiazide. Mapiritsi a Lozap 12.5 mg ali ndi mawonekedwe a oblong biconvex, amapaka utoto yoyera kapena pafupifupi yoyera ndipo amapezeka m'matumba a zidutswa 30, 60 ndi 90. Mapiritsi a Lozap 50 mg ndi 100 mg ndi oblong biconvex mawonekedwe, opakidwa zoyera kapena pafupifupi oyera, amakhala oopsa mbali zonse ziwiri ndipo amapezeka m'matumba a zidutswa 30, 60 ndi 90. Mapiritsi a Lozap kuphatikizika amakhala osalala, opakidwa utoto wonyezimira, amakhala oopsa mbali zonse ziwiri ndipo amapezeka m'matumba a zidutswa 10, 20, 30 ndi 90.

Zozap

Zithandizo zochizira Lozap ndikuchepetsa kuthamanga kwa magazi ndikuchepetsa katundu pamtima. Mphamvu ya mankhwalawa imaperekedwa chifukwa cha kuponderezedwa kwa ntchito ya angiotensin-kutembenuza enzyme (ACE), yomwe imatsimikizira kutembenuka kwa angiotensin I kuti angiotensin II. Ndi chifukwa chakuti Lozap imalepheretsa enzyme, ili m'gulu la zoletsa zoletsa za ACE.

Chifukwa cha zomwe Lozap amachita, angiotensin II sapangidwe m'thupi la munthu - chinthu chomwe chimapangika m'mitsempha yamagazi ndipo, chifukwa chake, chimawonjezera kuthamanga kwa magazi. Ngati mapangidwe a angiotensin II atsekedwa, ndiye kuti ziwiya sizichepa, ndipo kuthamanga kwa magazi kumachepa kapena kutsalira mwa malire. Poyerekeza ndi kagwiritsidwe ntchito ka Lozap pafupipafupi, kuthamanga kwa magazi kumachepa ndipo kumangosungidwa mkati mwabwinobwino. Kuphatikiza apo, woyamba hypotensive zotsatira zimawonedwa kale 1 - 1.5 mawola atatha kumwa mankhwalawa kwa tsiku limodzi, koma kuti muchepetse kupanikizika, muyenera kumwa mankhwalawa kwa pafupifupi milungu 4 - 5. Kuchepetsa kuponderezedwa kumathandiza kwambiri kwa okalamba ndi achinyamata omwe akudwala matenda oopsa oopsa.

Chifukwa cha kuchuluka kwa mitsempha yamagazi, Lozap imachepetsa katundu pamtima, zomwe ndizosavuta kukankhira magazi kudzera mwa iwo. Chifukwa cha kuthandizira kwa mtima, mankhwalawa amathandizira kulolerana kwa kupsinjika kwa thupi ndi malingaliro mwa anthu omwe akudwala matenda a mtima.

Lozap imathandizanso kuti magazi azikhala ndi mtima komanso kuchuluka kwa magazi a impso, ndichifukwa chake imagwiritsidwa ntchito bwino pochiza matenda osalephera a mtima komanso matenda a shuga.

Lozap imaphatikizidwa bwino ndi mankhwala ena a antihypertensive ndipo imakhala ndi mphamvu yotulutsa mphamvu, chifukwa thupi silisunga madzimadzi ndipo silipanga edema.

Lozap kuphatikiza imatanthauzanso mphamvu kwambiri poyerekeza ndi Lozap, popeza hydrochlorothiazide diuretic yophatikizidwa ndi kapangidwe kake imathandizira mphamvu ya ACE inhibitor.

Payokha, ziyenera kudziwika kuti Lozap imachulukitsa kuchuluka kwa uric acid, motero, imachepetsa kuyika kwake m'magazi.

Mukasiya kutenga Lozap ndi Lozap kuphatikiza, matenda "oletsa" samakhala.

Malangizo ogwiritsira ntchito Lozap

Piritsi ya lozap yamtundu uliwonse imatha kutengedwa mosasamala kanthu ndi chakudya, kummeza lonse, osafuna kutafuna kapena kuwuphwanya mwanjira ina iliyonse, koma ndi madzi ochepa (theka lagalasi ndilokwanira). Popeza mankhwalawa amakhala ndi mphamvu yayitali, mankhwala onse ofunikira tsiku lililonse amatengedwa kamodzi, ndiye kuti, mapiritsi amamwa 1 nthawi patsiku. Ndi bwino kumwa mankhwalawa tsiku lililonse nthawi yomweyo, makamaka madzulo.

Mlingo wa Lozap umatsimikiziridwa ndi matenda omwe mankhwalawa amatengedwa. Njira ya mankhwala nthawi zambiri imakhala yayitali - kuyambira miyezi ingapo mpaka zaka zingapo. Kutalika kwa mankhwalawa kumatsimikiziridwa payekhapayekha, kutengera kuchuluka kwa zotsatira zoyipa / zoyipa.

Pankhani ya matenda oopsa, Lozap amalimbikitsidwa kutenga 50 mg kamodzi patsiku kwa nthawi yayitali. Nthawi zina, ngati pakufunika kukwaniritsa zovuta zowonjezera zochizira, mutha kuwonjezera kuchuluka kwa mankhwalawa mpaka 100 mg. Mulingo wa 100 mg amatengedwa kamodzi patsiku (nthawi yomweyo onse 100 mg), kapena kawiri pa tsiku kwa 50 mg. Kutsika kwamphamvu kwa kuthamanga kwa magazi kumawonedwa pambuyo pa milungu itatu kapena isanu mutamwa mankhwalawa. Popeza mankhwalawa samayambitsa matenda a kudzipatula ndipo amamugwirira ntchito mokwanira, mutha kuyamba kumwa mankhwalawo nthawi yokwanira - 50 mg patsiku.

Kulephera kwa mtima kosatha, Lozap akulimbikitsidwa kuti ayambe kumwa 12,5 mg kamodzi patsiku. Pa mlingo uwu, mankhwalawa amatengedwa sabata limodzi. Kenako, mankhwalawa amawirikiza kawiri ndipo mankhwalawa amatengedwa pa 25 mg kamodzi patsiku kwa sabata lina. Zitatha izi, mphamvu ya mankhwalawa imawunikidwa ndipo ngati kuopsa kwa vutoli sikokwanira, mulingo womwewo umapangidwanso - mpaka 50 mg kamodzi patsiku. Mlingo wa Lozap ukamabwera ndi 50 mg patsiku, suwonjezanso ndipo mankhwalawo amatengedwa ochuluka. Ngati mankhwalawa pa mlingo wa 50 mg sagwira ntchito, ndiye kuti muyenera kusintha ena, koma musawonjezere Mlingo. Ngati mulingo wa 25 mg patsiku umagwira, ndiye kuti muyenera kumwa mankhwalawa, osachulukitsa mpaka 50 mg.

Mukamagwiritsa ntchito mankhwalawa kuchepetsa chiopsezo chokhala ndi matenda amtima komanso kuchepetsa kufa kwa anthu omwe ali ndi matenda oopsa kapena obowozera kwamitsempha yamagazi, muyenera kuyamba kumwa Lozap 50 mg kamodzi patsiku. Pambuyo pa masabata awiri kapena atatu atatha mankhwalawa, mphamvu yake imawunikiridwa. Ngati izi ndizokwanira, ndikulimbikitsidwa kuti mupitilize kumwa Lozap 50 mg kamodzi patsiku kwa nthawi yayitali. Ngati ntchitoyo siyokwanira, ndiye kuti mulingo wa Lozap uyenera kuchuluka mpaka 100 mg, kapena mlingo wa Lozap uyenera kusiyidwa wosasinthika, koma hydrochlorothiazide iyenera kuwonjezeredwa 50 mg patsiku. Mulingo wa 100 mg umatha kumwa kamodzi patsiku, ndiye kuti onse 100 mg nthawi imodzi, kapena kawiri patsiku (50 mg m'mawa ndi madzulo).

Kusamalira magwiridwe antchito a impso ndi matenda a shuga, kuphatikiza matenda oopsa, m'magawo oyamba a Lozap amatenga 50 mg kamodzi patsiku, ndipo pakatha milungu 1 mpaka 2, onjezani mlingo mpaka 100 mg patsiku. Ndi 100 mg patsiku lomwe Lozap iyenera kutengedwa pakanthawi yayitali mankhwala a impso. Mlingo wa 100 mg wa Lozap ukhoza kutengedwa nthawi imodzi kapena kugawidwa pawiri - 50 mg 2 kawiri pa tsiku.

Ngati diuretic imatengedwa nthawi yomweyo, kapena munthu akudwala matenda osowa madzi m'mimba (mwachitsanzo, mutatha kusanza, kutsegula m'mimba, ndi zina), ndiye kuti mlingo wa Lozap uyenera kuchepetsedwa mpaka 25 mg wa patsiku.

Anthu achikulire (opitilira zaka 65) ayenera kumwa Lozap muyezo, sizofunika kuti muchepetse. Komabe, anthu opitilira zaka 75 ndipo akuvutika ndi matenda a chiwindi, kuchepa magazi, komanso hemodialysis ayenera kumwa mankhwalawa 25 mg kamodzi patsiku. Mutha kuwonjezera kuchuluka kwa magawo amenewa mpaka kufika pa 50 mg patsiku.

Mlingo wovomerezeka wa Lozap tsiku lililonse ndi 150 mg.

Lozap Plus - malangizo

Mapiritsi amatengedwa pakamwa, osasamala chakudya, kuwameza iwo onse, osaluma, kutafuna kapena kuwaza mwanjira ina iliyonse, koma ndi madzi ochepa (theka lagalasi ndikokwanira).

Ndi ochepa matenda oopsa, mankhwalawa amayamba kumwa piritsi limodzi kamodzi patsiku. Pambuyo pa milungu itatu kapena isanu, yeretsani kuchuluka kwa mankhwalawa ndi phindu la kuthamanga kwa magazi. Ngati kupanikizika kwatsika pamiyezo yovomerezeka, ndiye kuti Lozap kuphatikiziranso akupitiliza kumwa, ndiye kuti piritsi limodzi 1 nthawi patsiku. Ngati, pakadatha masabata atatu kapena asanu atayamba kumwa mankhwalawo, magaziwo sangathe kubweretsa mfundo zovomerezeka, ndiye kuti mlingowo uyenera kuwonjezeredwa pamapiritsi awiri, omwe ayenera kumwedwa nthawi imodzi.

Kuti muchepetse chiopsezo cha matenda amtima komanso kufa kwa anthu omwe ali ndi vuto losakanikirana kwa magazi ndi matenda amitsempha yama mtima,, Lozap iyenera kutengedwa piritsi limodzi kamodzi patsiku. Ngati pakadatha masabata atatu kapena asanu mutangoyamba kugwiritsa ntchito, zovuta zakuchiritsidwazo sizokwanira, ndiye kuti kuchuluka kwa Lozap kuphatikizanso kuyenera kuwiriridwa kawiri ndipo mapiritsi awiri ayenera kumwedwa kamodzi patsiku.

Mlingo wovomerezeka wa Lozap tsiku lililonse ndi mapiritsi awiri.

Akuluakulu ayenera kumwa Lozap Plus mu Mlingo wabwinobwino popanda kuwachepetsa.

Gwiritsani ntchito panthawi yoyembekezera komanso poyamwitsa

Lozap ndi Lozap kuphatikiza sikulimbikitsidwa kuti mugwiritse ntchito panthawi yoyamba ya mimba (mpaka ndi sabata la 13 la bere), komanso lachiwiri ndi lachitatu, mankhwalawa ali otsutsana kwathunthu.

Izi zikutanthauza kuti kuyambira kuchiyambiyambi mpaka sabata la 13 la kubereka ndi bwino kusiya kugwiritsa ntchito mankhwalawa, koma ngati pali chosowa chofunikira, phindu lomwe mosakayikira limaposa zovuta zonse, Lozap kapena Lozap kuphatikizanso lingagwiritsidwe ntchito.

Kuyambira sabata la 14 la mimba mpaka kubadwa kwa Lozap ndi Lozap, kuphatikiza ndizotsutsana. Ndiye kuti, mankhwalawa sayenera kumwa nthawi iliyonse panthawi yomwe II ndi III amatenga pakati.

Amayi omwe akutenga Lozap kapena Lozap kuphatikiza omwe akukonzekera kutenga pakati ayenera kusintha mankhwalawa kuti atenge mankhwala ena a antihypertensive omwe amaloledwa kugwiritsidwa ntchito pakubala kwa mwana (mwachitsanzo, Nifedipine, ndi ena otero). Mimba ikakhala kuti simunakonzekere, ndiye kuti muyenera kukana kutenga Lozap kapena Lozap kuphatikizira nthawi yomweyo zitadziwika kuti ndi pakati.

Lozap ndi Lozap kuphatikiza, pakagwiritsidwe ntchito ka gawo lachiwiri komanso lachitatu la mimba, imakhala ndi poizoni pa mwana wosabadwayo, imayambitsa matenda aimpso, kuchepetsa kuchepa kwa mafupa a chigaza ndi kupangitsa mapangidwe a oligohydramnios.Chifukwa cha izi, Lozap kapena Lozap kuphatikiza zimatha kupangitsa kulephera kwa impso, hypotension ndi hyperkalemia mwa khanda lobadwa kumene. Lozap kuphatikiza, ikagwiritsidwa ntchito pa nthawi ya pakati, imatha kuyambitsa kuchepa kwa magazi a fetoplacental komanso kuphwanya koyenera kwamadzi, komanso jaundice mwana wosabadwa ndi wakhanda.

Chifukwa chake, ngati pazifukwa zina mkazi panthawi yoyembekezera amatenga kamodzi mwa Lozap kapena Lozap Plus, kuwunika kwa mwana wosabadwayo kuyenera kuchitidwa nthawi ndi nthawi kuti athe kuzindikira kuphwanya impso komanso kufinya mafupa a chigaza. Makanda obadwa kumene kwa azimayi omwe amatenga Lozap kapena Lozap Plus amayenera kuyang'aniridwa ndi madokotala chifukwa choopsa kwambiri cha hypotension (kuthamanga kwa magazi).

Lozap ndi Lozap kuphatikiza siziyenera kugwiritsidwa ntchito pakubala, popeza mankhwalawa amatha kupangidwira mkaka ndikuwononga thupi la mwana. Chifukwa chake, ngati pakufunika kugwiritsa ntchito Lozap kapena Lozap kuphatikiza, muyenera kukana kuyamwitsa ndi kusamutsa mwanayo kumakanidwe osokoneza bongo.

Analogs Lozap

Lozap ndi Lozap kuphatikiza pa msika wogulitsa mankhwala a mayiko a CIS ali ndi mitundu iwiri ya analogues - awa ndi ofananizana ndipo, makamaka, analogues. Ma Synonyms amaphatikiza mankhwala omwe ali ndi zinthu zofanana ndi Lozap ndi Lozap kuphatikiza. Ma analogues amaphatikizapo mankhwala omwe ali ndi zinthu zina zogwira ntchito, koma ali ndi zofanana kwambiri pochiritsa ndi Lozap ndi Lozap kuphatikiza. Mwakutero, ma analogi a Lozap ndi mankhwala osokoneza bongo omwe ali m'gulu la ACE inhibitors, ndipo Lozap kuphatikiza ndi ACE inhibitors kuphatikiza ndi diuretics.

Zofananira Lozap ndi Lozap kuphatikizanso zikuwonetsedwa pagome.

Analogs a Lozap ndi Lozap kuphatikizanso akuwonetsedwa pagome.

Anafananizira achi Russia Lozap

Ma Synonyms ndi fanizo la Lozap ndi Lozap kuphatikiza pakupanga kwa Russia akuwonetsedwa patebulopo.

Ndemanga zambiri za Lozap ndizabwino (kuchokera 85 mpaka 90%), zomwe zimachitika chifukwa cha kuyendetsa bwino kwambiri kwa mankhwalawa pakuchepetsa ndikukhalabe ndi magazi ovomerezeka. Zowunikira zikuwonetsa kuti Lozap inali yothandiza ngakhale pena pomwe mankhwala ena sangathe kuthana ndi ntchito yotsitsa ndikusunga kuthamanga kwa magazi mkati mwazolowereka.

Ndemanga zoyipa za Lozap ndizochepa ndipo zimayambitsa, monga lamulo, chifukwa chosagwiritsa ntchito mankhwalawo munjira inayake. Kuphatikiza apo, pali malingaliro oyipa okhudzana ndi mankhwalawa okhudzana ndi zovuta zomwe zimalekerera, mawonekedwe omwe adakakamiza kusiya kugwiritsa ntchito Lozap.

Lozap Plus - ndemanga

Ndemanga zambiri za Lozap kuphatikiza zabwino (zopitilira 90%), zomwe zimachitika chifukwa chakugwiritsa ntchito mankhwalawa. Chifukwa chake, pazowunikira kukuwonetseredwa kuti Lozap kuphatikiza bwino imachepetsa kuthamanga kwa magazi ndikuisunga mkati mwa zovomerezeka. Komanso, mphamvu ya mankhwalawa ndi yayitali, yomwe imakupatsani mwayi woti mumwe kamodzi patsiku, ndipo ndizothandiza kwambiri.

Ndemanga zoyipa za Lozap kuphatikiza, monga lamulo, zimayambitsidwa ndi zotsatira zoyipa, zomwe zinali zovuta kulekerera ndikukakamizidwa kusiya kugwiritsa ntchito mankhwalawa. Kuphatikiza apo, pali ndemanga za anthu pawokha zomwe zikuwonetsa kuti mtengo / magwiridwe antchito siwokwanira mokwanira.

Lozap - ndemanga za madokotala

Malingaliro a madotolo pa Lozap ndi Lozap kuphatikiza amasiyanasiyana. Chifukwa chake, madotolo amawona kuti mankhwalawa ndi abwino ndipo, motero, amangoyankha pokhapokha ngati ali ndi matenda ochepa oopsa. Ndiye kuti, ngati munthu ali ndi matenda oopsa, ndiye kuti Lozap kapena Lozap kuphatikiza ndi othandiza ndipo angagwiritsidwe ntchito bwino pochiritsa kwakanthawi.

Ngati matenda oopsa kwambiri komanso ophatikizana ndi matenda a mtima, ndiye kuti mphamvu ya Lozap ndiyotsika kwambiri. Kuchita kwa mankhwalawa ndikokwanira kwa maola asanu mpaka asanu ndi atatu, chifukwa chomwe anthu amapitanso kumwa mankhwala ena amphamvu, owonjezera. Chifukwa chake, muzochitika zoterezi, sikwachilendo kumwa Lozap, chifukwa muyenera kuyang'ana nthawi yomweyo zamankhwala ena amphamvu kwambiri, mwachitsanzo, beta-blockers.

Mapiritsi a kukakamiza Lozap: malangizo ogwiritsira ntchito

Monga tanena kale, njira imodzi yokhazikitsira kukakamiza kwa Lozap ndi magome. Mankhwalawa amapangidwa mu mitundu ingapo: 12.5, 50 ndi 100 mg. Mapiritsiwo ali ndi mawonekedwe a obic biconvex, amtundu woyera, amapangidwa m'matuza No. 30, 60, 90. Pali chida china chogwira - Lozap kuphatikiza. Mankhwalawa ali ndi zofanana zofanana, komabe, mosiyana ndi mapiritsi a kukakamiza, Lozap imagwira ntchito kwambiri. Ndipo izi zikuchitika chifukwa chakuti kapangidwe ka Lozap kuphatikiza, kuphatikiza pa yogwira potiniyamu, kumaphatikizanso hydrochlorothiazide, yomwe imathandizira kuchotsa madzi owonjezera, komanso kuwonjezera mphamvu ya gawo loyambirira.

Press mapiritsi Lozap adalembedwa mankhwala:

• ochepa matenda oopsa
• Kulephera kwa mtima (kuphatikiza chithandizo),
• matenda ashuga nephropathy.

Kuphatikiza apo, mankhwalawa amalembedwa kwa anthu omwe ali ndi chiopsezo chowonjezereka cha CVS, makamaka stroke, komanso kuchepetsa kufa kwa odwala omwe ali ndi vuto la kuthamanga kwa magazi ndi kumanzere kwamitsempha yamagazi.

Mapiritsi a kukakamiza Lozap amatsutsana mwa anthu omwe ali ndi kupezeka kwa: kuleza mtima, kulephera kwa impso, matenda a anuria, matenda osokonezeka a impso, hypoglycemia, hypercalcemia, matenda oletsa kupweteka kwa m'mimba, cholestasis, gout.

Anthu akuvutika ndi:

• kuthamanga kwa magazi
• Matenda a mtima wa Ischemic,
• arrhythmias
• matenda ashuga
• myopia kapena glaucoma,
• zovuta zolumikizana ndi minofu,
• hypertrophic obstriers cardiomyopathy,
• chiwindi kapena kulephera kwa impso, imwani mankhwalawa mosamala kwambiri.

Kuphatikiza apo, anthu okalamba, komanso omwe adasinthira impso, komanso omwe akuyenera kugwiritsa ntchito NSAIDs, mwachitsanzo, Nimesulide, Ibuprofen, Nurofen, sankhani mosamala Mlingo ndi regimen.

Sikulimbikitsidwa kugwiritsa ntchito mankhwalawa azimayi oyembekezera komanso oyamwitsa, komanso ana. Mankhwalawa atha kukhala osokoneza mwana.

Kulandila kosayenera, kulephera kutsata mlingo womwe dokotala wakupereka, kapena makamaka, waukulu, umakhala wolakwika. Chifukwa chake, musanayambe kumwa mankhwalawa, funsanani ndi katswiri woyenera ndikusanthula malangizowo.

Ngati mankhwala ambiri osokoneza bongo atha kupezeka, zizindikiro zotsatirazi zitha kuoneka: kuchepa madzi m'thupi, kugwa, kukomoka ndi kukomoka, kuchepa kwa magazi ndi ma electrolyte, kuchepa kwambiri kwa magazi, komanso tachycardia.

Ngati mankhwala osokoneza bongo amakula, mankhwala opatsirana amathandizira kuti thupi lizigwira ntchito bwino. Ngati, chifukwa cha kumwa mankhwalawo, kupanikizika kwatsika kwambiri, wodwalayo ayenera kuyikidwa pansi ndipo nthawi yomweyo ndikukweza kumapeto kwa phazi. Ngati pakufunika izi, wodwalayo adayambitsa kuyambitsa saline kapena sympathomimetics. Kuchita izi kumathandizanso kuteteza magazi. Pofuna kuchotsa mankhwalawa m'thupi posachedwa, okodzetsa ndi mankhwala.

Kuphatikiza apo, munthawi ya mankhwala ndi Lozap, mawonekedwe a zovuta kuchokera:

• hematopoietic dongosolo: anemia, eosinophilia, thrombocytopenia,
• chitetezo chokwanira: kuyabwa ndi totupa, edema ya Quincke, zithunzi, urticaria,
• CNS: sciatica, chisokonezo, mitsempha, kunjenjemera, kupuwala, kugona, chizungulire, malaise, kukhumudwa, nkhawa,
• STS: kugunda kwamtima wamunthu, kukomoka, kutseguka, kuchepa kwa magazi, epistaxis, hypotension ya orthostatic, bradycardia, block atrioventricular II, kugunda kwamtima,
• kupuma dongosolo: dyspnea, kupweteka pachifuwa, bronchitis, pharyngitis, laryngitis, mphuno, sinusitis, kupuma movutikira, kutsokomola, kuperewera kwammphuno,
• Matumbo: kupweteka kwa epigastrium, kusokonezeka kwa chopondapo (kutsekula m'mimba kapena kudzimbidwa), xerostomia, gastritis, hepatitis, nseru, kusanza, kugonja, kugwedezeka, matumbo
• genitourinary dongosolo: Kulephera kwa ntchito kwa impso, kusabala, kulephera kwa impso, kutsika libido, nocturia.

Ngati zizindikiro zomwe zili pamwambazi zikuwoneka, dziwitsani dokotala nthawi yomweyo.

Mankhwala a Lapoz okakamiza: momwe mungatengere, kuyanjana ndi mankhwala ena

Mankhwala a Lozap opsinjika amatha kugwiritsidwa ntchito mosasamala chakudya. Piritsi limamezedwa lonse, silifunikira kuti lidzaphwanyidwe kapena kutafunidwa. Mankhwalawa amatsukidwa ndi madzi. Popeza mankhwalawa Lozap wopanikizika amakhala ndi mphamvu yayitali, mulingo wonse wa tsiku ndi tsiku umatengedwa pa mlingo umodzi, ndiye kuti, kugwiritsa ntchito piritsi limodzi kumayikidwa kamodzi patsiku. Ndikofunikira kugwiritsa ntchito mankhwalawa tsiku lililonse nthawi yomweyo madzulo.

Mlingo wofanana ndi mtundu wa mankhwala amasankhidwa ndi adokotala, kutengera matendawa. Njira yokhazikika, monga lamulo, ndi yayitali - kuyambira mwezi mpaka zaka zingapo.

Kutalika kwa mankhwalawa ndi Lozap kumasankhidwa kokha payekhapayekha, ndikuyenera kuganizira zoyenera ndi zovuta zina.

1. Zochizira matenda oopsa, ma milligram makumi asanu a mankhwala amayikidwa kamodzi patsiku. Njira yochizira matendawa ndi yayitali. Nthawi zina, kuti mupeze phindu labwino, mulingo umachulukitsa mpaka ma milligram zana. Pa mlingo uwu, mankhwalawa amatengedwa kamodzi kapena kawiri patsiku, 50 mg iliyonse.
   Kutsika kwa kuthamanga kwa magazi pambuyo pakugwiritsidwa ntchito kwa mankhwala a Lozap pokakamizidwa kumawonedwa, monga lamulo, patatha mwezi umodzi ndikuchita mankhwalawa. Popeza mankhwalawa sakukhumudwitsa achire, mayendedwe ake ndi odekha, chithandizo chimatha kuyamba nthawi yomweyo ndi mlingo wathunthu - ma milligram makumi asanu patsiku.
2. Kuthana ndi matenda monga mtima Kulephera, 12,5 mg kamodzi patsiku. Mankhwala omwe ali mu mankhwalawa amayenera kumwa kwa sabata limodzi. Kuphatikiza apo, mulingo wowirikiza umachulukitsidwa. Mlingo wa 25 mg ndi mankhwala kamodzi patsiku. Kenako, mphamvu ya mankhwalawa imawunikiridwa, ndipo ngati zotsatira zake sizinenedwenso, muyezo umakulitsidwa mpaka ma milligram makumi asanu. Mlingo wake ndi wokwanira. Ngati kuchuluka kwa kuchuluka kwa mankhwalawo sikunatchulidwe, mankhwalawo amaloledwa ndi wina. Pomwe mlingo wa 25 mg ungagwire bwino, sasintha.
3. Pofuna kuchepetsa mwayi wokhala ndi CVD pathologies, komanso kuchepetsa kufa kwa odwala omwe ali ndi matenda oopsa ndipo amasiya maekitiroferiya ang'ono, ma milligram makumi asanu a mankhwala a Lozap amakakamizidwa kamodzi patsiku. Pambuyo pa theka la mwezi, yeretsani zotsatirazo. Ngati ndikwanira, dongosolo la mankhwalawo limakulitsidwa kwa nthawi yayitali. Ngati vutoli silikumveka, mlingo umakulitsidwa mpaka 100 mg patsiku. Nthawi zina amachita mosiyanasiyana - amapereka mankhwala ophatikiza: 50 mg ya Lozap yatsala ndipo 50 mg ya hydrochlorothiazide imawonjezeredwa.
4. Pofuna kupitiliza kugwira ntchito kwa kwamikodzo mu matenda ashuga osakanikiridwa ndi matenda oopsa, ma milligram makumi asanu a mankhwalawa amaperekedwa tsiku limodzi masabata awiri. Kenako, mlingo ukuwonjezeka mpaka 100 mg. Kwa chithandizo chakanthawi kovutikira kwa kwamikodzo, Lozap amatchulidwa pa 100 mg kamodzi patsiku.

Ngati wodwala wapatsidwa mankhwala osokoneza bongo, ndipo amatenga okodzetsa limodzi ndi Lozap, kapena ali ndi vuto lotha kusowa madzi, mwachitsanzo, kutsegula m'mimba kapena kusanza, mlingo umachepetsedwa mpaka 25 mg patsiku. Okalamba amalamula kuti mankhwalawa agwiritsidwe ntchito muyezo, samachepetsedwa kapena kuwonjezeka. Mlingo wovomerezeka wa Lozap umaganiziridwa - ma milligram 300.

Mankhwala ali contraindified mu mimba ndi HB. Amayi omwe amamwa mankhwalawa ndikukonzekera kukhala ndi pakati amalangizidwa kuti akaonane ndi dokotala kuti alowe m'malo mankhwalawa. Ngati mimba sinakonzekere kumwa mankhwalawa, muyenera kukana.

Lozap imawononga kwambiri mwana wosabadwayo, imayambitsa matenda aimpso, komanso imachepetsa kufupika kwa mafupa a chigaza. Kumwa mankhwalawa panthawi yoyembekezera kumawonekera ndikukula kwa impso, hypercalcemia ndi hypotension kwa mwana wakhanda.

Mankhwalawa sayenera kumwa ndi azimayi omwe akuyamwitsa. Zosakaniza zomwe zimagwira zimatha kulowa mkaka ndikuwononga thupi la mwana. Pankhaniyi, amasinthana ndi mankhwalawo, kapena amasinthana ndi zosakaniza zosakanikira.

Kuvomerezeka kwa mankhwalawa kungathe kuperekedwa ndi katswiri woyenera. Osadzisilira. Zokhudza thupi la Lozap zimatha kusintha mosiyanasiyana, koma nthawi zambiri zimakhala zowononga, makamaka ngati zikuyenera kutengedwa ndi njira zina. Tsopano zambiri za mankhwala:

• Mukamagwiritsa ntchito Lozap osakanikirana ndi Fluconazole kapena Rifampicin, kuchepa kwa kugwiritsidwa ntchito kwa zinthu Lozap kumadziwika,
• Mukamatenga Lozap ndi okodzetsa, makamaka Veroshpiron kapena Amilorid kapena kukonzekera kwa potaziyamu - Asparkam, Panangin, kuchuluka kwa potaziyamu m'magazi ndikotheka,
• kutenga Lozap kuphatikiza ndi kukonzekera kwa lifiyamu kumangokhala pang'ono pang'onopang'ono pochotsa lithiamu mthupi,
• ndi kuphatikiza kwa Lozap ndimankhwala ena ochepetsa anzawo (Atenolol, Metoprolol), zotsatira za beta-blockers zimakulitsidwa,
• kugwiritsa ntchito munthawi yomweyo mankhwala omwe amafunsidwa ndi NSAIDs (Ibuprofen, Aspirin, Ketanov) ndiwochedwa kuchepa kwa mphamvu ya Lozap komanso chiwopsezo chokhala ndi matenda a impso.
• kutenga Lozap ndi zoletsa za ACE, mwachitsanzo, Captopril, Enalapril, amakhala ndi kuphwanya kwa magwiridwe antchito a kwamikodzo ndikuphwanya mulingo wamagetsi wamagetsi.
• kugwiritsa ntchito Lozap kuphatikiza tetracyclic antidepressants kungayambitse kuchepa kwamphamvu kwa magazi,
• mukamagwiritsa ntchito Lozap ndi glucocorticosteroids (Prednisolone, Betamethasone), pali kuchepa kwa ma electrolyte: calcium, sodium, potaziyamu,
• ndi kuphatikiza kwa Lozap ndi adrenaline, kuchepa kwakuopsa kwa zochita za wachiwiri kumadziwika,
• Kugwiritsa ntchito limodzi kwa Lozap ndi mankhwala osokoneza bongo a antiarrhythmic (Disopyramide, Quinidine), antipsychotic (Droperidol, Thiapride, Pimozide), komanso Vincamycin, Erythromycin, Cisapride, Terfenadine ndiwofundidwa ndi kukula kwa makonzedwe ake.
• kutenga Lozap ndi angiotensin kutembenuza enzyme inhibitor ndiwofupi ndi kukula kwa zovuta zoyipa, makamaka ochepa hypotension, kukomoka.

Lozap ndiwothandiza kwambiri antihypertensive othandizira omwe amathandizira kuchepa kwa magazi, makamaka kufalikira kwa m'mapapo, amachepetsa pambuyo pake, komanso osagwiritsa ntchito peptide blocker ya AT2 receptors yomwe imapangitsa kuchuluka kwa matenda oopsa, kumasulidwa kwa aldosterone, renin, ndi vasopressin; zotsatira ndi kuyanjana ndi mankhwala ena.

Mankhwala Lozap ndi Lozap Plus: analogues, mtengo ndi ndemanga

Nthawi zambiri amafunsa funso kuti: "Kodi ndiubwino uti - Lozap kapena Lorista?". M'malo mwake, mankhwalawa ali ndi chophatikizira chomwecho - potaziyamu losartan. Lorista amalembedwa komanso Lozap kwa anthu omwe ali ndi mavuto monga kuperewera kwa mtima, matenda oopsa. Kukula kwake ndi zomwe mankhwalawa ali pafupifupi.

Kusiyanitsa kwakukulu ndi mtengo wotsika wa Lorista, womwe ndiye mwayi waukulu wa mankhwalawa. Mtengo wapakati wa Lozap No. 30 ndi ma ruble 300, mu Lorista - ma ruble 150. Tengani analogue yotsika mtengo kokha ngati chilolezo cha dokotala.

Kodi pali kusiyana kotani pakati pa Lozap ndi Lozap Plus?

Ngati mukufunikira kumwa mankhwalawa pogwiritsa ntchito chida ichi, funso likubwera, kodi mankhwala abwino kwambiri a Lozap kapena Lozap Plus ndi ati.

Kusiyanitsa kwakukulu ndikuti mankhwala achiwiri amaphatikizidwa - zinthu zomwe zimagwiritsidwa ntchito ndi losartan potaziyamu ndi hydrochlorothiazide, yomwe ndi okodzetsa komanso amakhala ndi diuretic.

Mankhwalawa onse ndi angiotensin receptor blockers. Amathandizira kupewa kuchepa kwa mitsempha. Kuchuluka kwa losartan mwa iwo ndi komweko, koma mankhwalawa a Lozap Plus amasiyana ndi Lozap pogwira ntchito kwambiri, chifukwa amapanga zinthu ziwiri zomwe zimagwirizana.

Kusiyana kwina pakati pa Lozap Plus ndi Lozap ndikuti yoyamba imapangidwa mu gawo limodzi - 50 mg ya losartan + 12,5 hydrochlorothiazide.

Pali zingapo zoyimira za mankhwalawa. Zodziwika bwino ndizophatikiza: Nortian, Irsar, Hyposart, Valz, Atakand, Naviten, Aprovel, Diovan, Kandekor, Mikardis, Valsartan.

Kuphatikiza pa izi, palinso maulumikizidwe a mankhwalawo omwe amafunsidwa - ali ndi zinthu zofanana: Brozaar, Vazotens, Losartan, Losakar, Lotor, Renikard, Lorista.

Komanso, adokotala amatha kupatsa mankhwala mankhwala kutengera mankhwala a guanfacin.

Mtengo wapakati wa Lozap 12.5 No. 30 ndi ma ruble 200, 12,5 No. 90 ndi ma ruble 550, 50 mg No. 30 ndi 270 rubles, 50 mg No. 60 ndi 470 rubles, 50 mg No. 90 90 ndi 670 rubles, 100 mg No. 30 ndi ruble 200, 100 mg No. 60 - ma ruble a 560, 100 mg No. 90 - 750 rubles.

Mtengo wamba wa Lozap kuphatikiza 12.5 mg No. 30 ndi rubles 350, ndipo ayi 90 ndi 800 rubles.

Valery, wazaka 54, adapuma pantchito

“Ndidapatsidwa mwayi woyang'anira Lozapa. Zinatenga nthawi yayitali, zotsatira zake zinali zabwino. Ululu mumtima unachepa, kukakamira sikunalumphe, kunkangokhazikika, komanso thanzi linaliwoneka bwino. Ndikulimbikitsa aliyense, mankhwala othandiza kwambiri. ”

Diana, wazaka 52, kuphika

“Ndi ukalamba, mavuto amabwera, makamaka, zolakwika pamtima. Nthawi zambiri ankadwala matenda othamanga magazi. Sindinapite kwa adotolo, ndikamwa piritsi ilo, lina. Mwana wanga wamkazi adalimbikira kupita kuchipatala. Dokotala adalamula Lozap. Zinatenga nthawi yayitali, koma zinali zaphindu. M'milungu iwiri yokha, adayamba kumva bwino. Kupanikizika ndikwachilendo ndipo sikumadumpha. "

Vladimir, wazaka 60, nzika yapamwamba

“Ndasweka mtima. Ndakhala ndikutenga Lozap kwa nthawi yayitali. Mapiritsi awa ndiabwino, koma nthawi zina ludzu lotere limatha kuti musathe kuledzera mwanjira iliyonse. Kuphatikiza apo, chifuwa chosaganiza nthawi zina chimachitika. Koma sizinthu zonse poyerekeza ndi momwe mankhwalawo amathandizira. Ndimalilandira molumikizana ndi ena, ndipo kunena zowona, ndili bwino kwambiri. "

Pharmacodynamics ndi pharmacokinetics

Lozap ndi mankhwala osokoneza bongo, okonda ena a angiotensin II receptors. Amachepetsa zotumphukira mtima kukana, otsika adrenaline ndi aldosterone m'magazi. Mothandizidwa ndi iye, kupanikizika kwa kufalikira kwam'mapapo kumachepa, mphamvu yokhudza kukodzeka kwa thupi imayamba, kenako kutsitsika kumatha. Lozap imalepheretsa njira zama hypertrophic za myocardium, zimathandizira kukulitsa kulolerana kwa masewera olimbitsa thupi kwa anthu omwe ali ndi vuto la mtima.

Mulingo woyenera kwambiri wodwala pambuyo pakumwa kamodzi kwa mankhwalawa umawonedwa pambuyo pa maola 6, pambuyo pake umatha kuchepa pakapita maola 24. Ndi chithandizo mwatsatanetsatane, kuchuluka kwake (kutsitsa magazi) kumachitika milungu itatu kapena isanu ndi umodzi atayamba chithandizo.

Tiyenera kukumbukira kuti mwa anthu omwe ali matenda amatsenga, imachulukitsa kuchuluka kwa ntchito yogwira (losartan) m'magazi am'magazi. Chifukwa chake, odwala oterowo amapatsidwa mlingo wapadera, wochepetsedwa.

Madzi am'mimba amachokera mofulumira. The bioavailability wa mankhwala pafupifupi 33%. Pambuyo pakulimbitsa pakamwa, ndende yapamwamba kwambiri ya plasma imakhalapo pambuyo pa ola limodzi. Kwambiri ndende ya mankhwala metabolite amawonedwa pambuyo maola 3-4. Hafu ya moyo wa losartan ndi maola 2, metabolite yogwira ndi maola 9. 35% ya mankhwalawa amamuchotsa mkodzo, pafupifupi 60% kudzera m'matumbo.

Kupanga ndi mawonekedwe a kumasulidwa

Lozap imapezeka m'mapiritsi (kuchuluka kwa 12.5 ndi 50 mg). Zomwe zimagwiritsidwa ntchito ndi losartan. Mapiritsi a Lozap malinga ndi malangizo ali ndi zinthu zothandiza zotsatirazi: microcrystalline cellulose, mannitol, colloidal silicon dioxide, crospovidone, talc, magnesium stearate, hypromellose, macrogol, titanium dioxide.

Mapiritsi a Lozap ndi oval, biconvex, filimu yokutira. Mankhwalawa amapangidwa matuza a mapiritsi 10. Phukusi la makatoni pakhoza kukhala ndi matuza 3, 6 kapena 9 okhala ndi malangizo.

Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere

Kafukufuku wazachipatala pakugwiritsa ntchito Lozap panthawi yapakati sanachitike. Tiyenera kudziwa kuti chowonadi chadziwika kuti mankhwala omwe amagwira pa angiotensin-aldosterol dongosolo amakhala ndi mphamvu ya teratogenic (imayambitsa kusokonezeka ngakhale kufa kwa fetal). Ngati mimba yachitika ndikugwiritsa ntchito Lozap, ndiye kuti iyenera kuthetsedwa nthawi yomweyo. Pa mkaka wa mkaka, mankhwalawa samalimbikitsidwanso kuti azigwiritsidwa ntchito.

Zotsatira zoyipa

Malinga ndi ndemanga, Lozap nthawi zambiri samayambitsa zovuta. Ngati zotsatira zoyipa zikuchitika, ndiye kuti izi zimachitika pang'onopang'ono ndipo kusiya mankhwala sikofunikira. Zotsatira zoyipa za Lozap pochiza matenda oopsa ndi chizungulire (4.1%). Mphamvu ya orthostatic ya Lozap malinga ndi ndemanga idadziwika mu zosakwana 1% za odwala.

Zotsatira zina za Lozap sikuti zimasiyana pakakumana ndi vuto la placebo ("dummy"), chifukwa chake mgwirizano wawo wogwiritsa ntchito mankhwalawa ndiwokayikira. Zotsatira zoyipa zimaphatikizana ndi asthenia, kutopa, kupweteka pachifuwa, kutupa kwa malekezero, kupweteka kwa m'mimba, kupweteka kwam'mimba, mseru, msana ndi / kapena kupweteka kwa mwendo, kukokana kwa minofu ya ng'ombe, kupweteka mutu, kusanza, chifuwa cham'mimba .

Kuchita ndi mankhwala ena

Malinga ndi malangizo, Lozap ikhoza kuphatikizidwa ndi mankhwala ena a antihypertensive, imathandizira pakumvera kwa opanga ndi omvera a beta-adrenergic.

Ndi kuphatikiza kwa Lozap komanso okodzetsa, kuwonjezeka kwa machitidwe onsewa kumadziwika.

Ndi munthawi yomweyo makonzedwe a digoxin, hydrochlorothiazide, warfarin, cimetidine, phenobarbital, erythromycin ndi ketoconazole, palibe kuyanjana kwa mankhwala komwe kunapezeka. Malinga ndi ndemanga, Lozap amayenda bwino ndi mankhwalawa, osayambitsa chilichonse.

Kugwiritsidwa ntchito kwa Lozap limodzi ndi potaziyamu wotsekemera okodzetsa (spironolactone, amiloride, triamteren) kumawonjezera chiopsezo cha hyperkalemia.

Lozap: mitengo pamafakitale opezeka pa intaneti

Zozap 12.5 mg yamafuta ophatikizika ndi mafilimu 30 ma PC.

LOZAP 12.5mg 30 ma PC. mapiritsi okhala ndi filimu

LOZAP AM 5mg + 50mg 30 ma PC. mapiritsi okhala ndi filimu

LOZAP 100mg 30 ma PC. mapiritsi okhala ndi filimu

LOZAP 100mg 60 ma PC. mapiritsi okhala ndi filimu

Zozap 12.5 mg yamafuta ophatikizika ndi mafilimu 90 ma PC.

LOZAP 50mg 30 ma PC. mapiritsi okhala ndi filimu

Zozap 50 mg yamafuta apiritsi 30 mg ma PC.

Zozap 100 mg yamafuta apiritsi 30 mg ma PC.

Tebulo la Lozap. p.p.o. 50mg n30

LOZAP AM 5mg + 100mg 30 ma PC. mapiritsi okhala ndi filimu

Tebulo la Lozap. p.p.o. 100mg n30

Lozap tbl p / pl / o 50mg No. 30

Lozap 50 mg 30 mapiritsi

LOZAP PLUS 50mg + 12.5mg 30 ma PC. mapiritsi okhala ndi filimu

Lozap Plus 50 mg + 12,5 mg mapiritsi okhala ndi mafilimu 30 ma PC.

Ndemanga Lozap Plus

Lozap kuphatikiza tabu. p.p.o. 50mg + 12.5mg n30

Lozap 100 mg 30 mapiritsi

Lozap AM 5 mg + 100 mg mapiritsi okhala ndi mafilimu 30 ma PC.

Lozap tbl p / pl / o 100mg No. 30

Lozap AM 5 mg + 50 mg wophatikizidwa ndi mafilimu 30 ma PC.

LOZAP 12.5mg 90 ma PC. mapiritsi okhala ndi filimu

Lozap kuphatikiza 50 mg kuphatikiza 12,5 mg 30 mapiritsi

Lozap ndine tabu. n / ogwidwa. 5 mg + 50 mg No. 30

Lozapas kuphatikiza tbl p / pl / o 50mg + 12.5mg No. 30

Zozap 50 mg yamafuta apiritsi 60 mg ma PC.

LOZAP 50mg 60 ma PC. mapiritsi okhala ndi filimu

Tebulo la Lozap. p.p.o. 50mg n60

Zozap 100 mg yamafuta-mapiritsi 100 mg ma PC.

Lozap am 5 mg kuphatikiza 100 mg 30 mapiritsi

Zozap 100 mg yamafuta-mapiritsi 60 mg ma PC.

Lozap am 5 mg kuphatikiza 50 mg 30 mapiritsi

Lozap ndine tabu. n / ogwidwa. 5 mg + 100 mg No. 30

Lozap AM tbl p / pl / o 5mg + 100mg No. 30

Lozap Plus 50 mg + 12,5 mg mapiritsi okhala ndi mafilimu 60 ma PC.

LOZAP PLUS 50mg + 12.5mg 60 ma PC. mapiritsi okhala ndi filimu

Lozap kuphatikiza tabu. p.p.o. 50mg + 12.5mg n60

Lozap AM tbl p / pl / o 5mg + 50mg No. 30

LOZAP 100mg 90 ma PC. mapiritsi okhala ndi filimu

Lozap 50 mg yamafuta ophatikizika ndi mafilimu 90 ma PC.

Lozap Plus 50 mg + 12.5 mg pamafilimu okhala ndi mafilimu 90 ma PC.

Ndemanga Lozap Plus

Lozap kuphatikiza 50 mg kuphatikiza mapiritsi a 12.5 mg 60

LOZAP 50mg 90 ma PC. mapiritsi okhala ndi filimu

Lozap tbl p / pl / o 100mg No. 90 *

Lozap kuphatikiza tbl p / pl / o 50mg + 12.5mg No. 60

Lozap kuphatikiza tabu. p.p.o. 50mg + 12.5mg n90

LOZAP PLUS 50mg + 12.5mg 90 ma PC. mapiritsi okhala ndi filimu

Lozapa kuphatikiza tbl p / pl / o 50mg + 12.5mg No. 90

Zambiri zokhudzana ndi mankhwalawa ndizofanana, zimaperekedwa pazidziwitso ndipo sizilowa m'malo mwa malangizo ovomerezeka. Kudzipatsa nokha mankhwala kuopsa!

Chiwindi ndi chiwalo cholemera kwambiri m'thupi lathu. Kulemera kwake pafupifupi 1.5 kg.

Malinga ndi kafukufuku, azimayi omwe amamwa magalasi angapo a mowa kapena vinyo pamlungu amakhala pachiwopsezo chotenga khansa ya m'mawere.

Vibrator woyamba adapangidwa m'zaka za zana la 19. Adagwira ntchito pa injini yankhonya ndipo adapangira kuti azitsatira khungu la akazi.

Mimba ya munthu imagwira ntchito yabwino ndi zinthu zakunja komanso popanda chithandizo chamankhwala. Madzi am'mimba amadziwika kuti amasungunula ngakhale ndalama.

Asayansi ochokera ku Oxford University adachita kafukufuku wambiri, pomwe adazindikira kuti zamasamba zimatha kuvulaza ubongo wa munthu, chifukwa zimapangitsa kuti kuchuluka kwake kuzikhala kochepa. Chifukwa chake, asayansi amalimbikitsa kuti asachotsere konse nsomba ndi nyama muzakudya zawo.

Asayansi aku America adayesera mbewa ndipo adati madzi amadzi amalepheretsa kukula kwa atherosulinosis yamitsempha yamagazi. Gulu limodzi la mbewa limamwa madzi am'madzi, ndipo lachiwiri ndi madzi a mavwende. Zotsatira zake, zombo za gulu lachiwiri zinali zopanda ma cholesterol.

Kuti tinene ngakhale mawu afupi komanso osavuta, timagwiritsa ntchito minofu 72.

Ngati mungagwere kuchokera pabulu, mukulola khosi lanu kusiyana ndi kugwa kuchokera pa kavalo. Ingoyesani kutsutsa mawu awa.

Mu 5% ya odwala, antidepressant clomipramine amayambitsa kuphipha.

Madokotala a mano adapezeka posachedwa. Kalelo m'zaka za zana la 19, inali ntchito ya tsitsi wamba kuti akatulutse mano odwala.

Pogwira ntchito, ubongo wathu umagwiritsa ntchito mphamvu zambiri zofanana ndi babu la 10-watt. Chifukwa chake chithunzi cha babu wapamwamba pamutu panu panthawi yomwe chikuwoneka ngati chosangalatsa sichili kutali ndi chowonadi.

Munthu amene amamwa mankhwala opondeleza nthawi zambiri amakhalanso ndi nkhawa. Ngati munthu athana ndi kukhumudwa paokha, ali ndi mwayi wonse wakuyiwalako zamtunduwu mpaka kalekale.

Mabakiteriya mamiliyoni ambiri amabadwa, amoyo ndi kufa m'matumbo athu. Amatha kuwoneka pa kukula kwakukulu, koma ngati atakhala palimodzi, akhoza kukhala mu kapu ya khofi yokhazikika.

Kulemera kwaubongo wamunthu kuli pafupifupi 2% ya kulemera konse kwathupi, koma kumadya pafupifupi 20% ya mpweya womwe umalowa m'magazi. Izi zimapangitsa kuti ubongo wamunthu ukhale wovuta kwambiri kuwonongeka chifukwa cha kusowa kwa mpweya.

James Harrison wazaka 74 yemwe amakhala ku Australia amakhala wopereka magazi pafupifupi nthawi 1,000. Ali ndi mtundu wamagazi osafunikira, ma antibodies omwe amathandizira akhanda omwe ali ndi vuto lalikulu la magazi kukhala ndi moyo. Chifukwa chake, waku Australia adapulumutsa ana pafupifupi mamiliyoni awiri.

Mphepo yoyamba ya maluwa ikufika kumapeto, koma mitengo yotulutsa maluwa idzasinthidwa ndi udzu kuyambira koyambirira kwa Juni, zomwe zimasokoneza omwe ali ndi vuto lodziwika bwino.

Pa mimba ndi mkaka wa m`mawere

Osamamuchitira Lozap panthawi yoyembekezera. Pa mankhwala lachiwiri ndi lachitatu trimesters ndi mankhwala omwe amakhudzanso renin-angiotensin, zolakwika mu chitukuko cha mwana wosabadwayo ndipo ngakhale imfa ingachitike. Mimba ikangochitika, mankhwalawa amayenera kuyimitsidwa nthawi yomweyo.

Ngati lozap iyenera kutengedwa panthawi yoyamwitsa, yoyamwitsa iyenera kuyimitsidwa nthawi yomweyo.

Ndemanga pa Lozap Plus ndi Lozap zikuwonetsa kuti nthawi zambiri, mankhwalawa amachepetsa kuthamanga kwa magazindikukhala ndi zotsatira zabwino paumoyo wa anthu omwe ali ndi matenda amtima. Odwala omwe amapita pagawo lodziwika kuti asiye ndemanga pa Lozap 50 mg amazindikira kuti kutsokomola, pakamwa pouma, komanso kuwonongeka kwa khutu nthawi zina kumadziwika ngati mavuto. Koma pazonse, ndemanga za odwala pazokhudza mankhwalawa ndi zabwino. Nthawi yomweyo, kuwunika kwa madotolo kukuwonetsa kuti mankhwalawa sangakhale oyenera kwa anthu onse omwe ali ndi vuto loipa lamankhwala. Chifukwa chake, poyamba ziyenera kutengedwa moyang'aniridwa ndi katswiri.

Mtengo, kuti mugule

Mtengo wa Lozap pama pharmacies umasiyana ndi ma ruble 230. (Lozap 12.5 mg, 30 ma PC.) Kufikira ma ruble 760 (Lozap 100 mg, 90 pcs.). Mtengo wa mapiritsi a Lozap 50 mg ku Moscow ndi mizinda ina ndi ruble 270-300. Nthawi zina mutha kugula mankhwala pamtengo wotsikirapo pazomwe mumalimbikitsa. Mtengo wa Lozap Plus 50 mg (mapiritsi 90) - kuchokera ku ruble 720.