Acarbose malangizo a odwala matenda ashuga mtundu 1 ndi 2, analogues

Wothandizira pakamwa wa hypoglycemic, poletsa matumbo alpha-glucosidase, amachepetsa kusintha kwa enzymatic kwa di-, oligo- ndi polysaccharides kukhala monosaccharides, potero amachepetsa kuyamwa kwa glucose kuchokera m'matumbo ndi postprandial hyperglycemia. Odwala omwe ali ndi vuto losagwirizana ndi shuga, kugwiritsa ntchito pafupipafupi kumachepetsa chiopsezo chokhala ndi matenda a shuga a 2 (kuphatikiza malingana ndi kafukufuku yemwe wakhungu la placebo-loyesedwa ndi STOP-N>).

Pogwiritsa ntchito acarbose, kukula kwa hypoglycemia sikokwanira. Komabe, kugwiritsa ntchito mankhwalawa mogwirizana ndi ma othandizira ena a hypoglycemic kapena insulini kungayambitse izi, chifukwa chake kuphatikiza koteroko sikulimbikitsidwa ndi malangizo a WHO. Zinapezekanso kuti zizindikiro za hypoglycemia zimayamba pamene acarbose amagwiritsidwa ntchito ndi anthu okalamba komanso ofooka, ngakhale palibe mankhwala ena othandizira odwala omwe amagwiritsidwa ntchito nthawi yomweyo, omwe amayeneranso kuganiziridwa popereka mankhwala kwa odwala a magulu awa.

M'maphunziro mu vitro ndi mu vivo palibe umboni wa mutagenicity. Kasamalidwe ka makoswe ndi chakudya sikukhudza chonde komanso kubereka kwathunthu.

Dongosolo la Pharmacokinetics

Mafuta - pafupifupi 35% ya mankhwala omwe amaperekedwa, mwina mawonekedwe a metabolites (omwe 2% - yogwira mawonekedwe), bioavailability ndi 1-2%. Pambuyo pakukonzekera pakamwa, nsonga ziwiri za ndende zimawonedwa: pambuyo pa maola 1-2 ndi pambuyo pa maola 14-24, kuwoneka kwa nsonga yachiwiri kumachitika chifukwa cha kuyamwa kwa metabolites kuchokera m'matumbo. Kugawa voliyumu - 0,39 l / kg. Odwala aimpso kulephera (kulengedwa kwa creatinine zosakwana 25 ml / mphindi / 1.73 m²), ambiri ndende (C_max) amachulukitsa ka 5, okalamba - nthawi 1.5.

Amapukusidwa kokha m'matumbo am'mimba, makamaka mabakiteriya am'mimba ndi michere pang'ono, ndikupanga mitundu ingapo ya 13. Ma metabolites ofunikira amadziwika kuti amachokera ku 4-methylpyrogallol (mu mawonekedwe a sulfate, methyl ndi glucuronic conjugates). Mmodzi metabolite, mankhwala opangidwa ndi molekyu wa glucose mu acarbose, amatha kuletsa alpha glucosidase.

Hafu ya moyo ( T_1/2 ) pagawo logawa - maola 4, magawo a zotupa - maola 10. Amatulutsidwa m'matumbo - 51% (mkati mwa maola 96) ngati zinthu za metabolic (acabsbose acarbose), ndi impso - 34% mu mawonekedwe a metabolites ndi ochepera 2% - osasinthika komanso monga metabolite yogwira.

Zowongolera Sinthani

Type 2 shuga mellitus (ndi kusachita bwino kwa mankhwala azakudya, njira yomwe iyenera kukhala osachepera miyezi isanu ndi umodzi, kusakwanira kofotokoza mankhwala ochokera kwa sulfonylurea motsutsana ndi zakudya zamagulu ochepa a calorie). Kupewa kwa matenda a shuga 2 a mitundu (odwala omwe ali ndi vuto la shuga) kuphatikizira ndi zakudya komanso masewera olimbitsa thupi.

Contraindication Sinthani

Hypersensitivity, shuga , kutsekeka m'matumbo (kuphatikiza kapena kupendekera kwake), kupindika komanso matumbo am'mimba, kulephera kwamkaka kwamizere (mawonekedwe ainine 2 pamtunda wa 2 m / DL), mimba, mkaka wa m'mawere.

Malangizo

Mankhwalawa amatengedwa pakamwa, osafuna kutafuna, ndi madzi pang'ono musanadye kapena ola limodzi mutatha kudya. Mlingo woyambirira ndi 50 mg × 3 katatu patsiku ndi kuwonjezeka pang'onopang'ono kwa mlingo umodzi mpaka 100-200 mg (kuchuluka kwa mankhwalawa kumachitika pambuyo pa masabata 4-8 a chithandizo chanthawi ya masabata a 1-2, kutengera glycemia ndi kulolerana kwa munthu payekha). Mlingo wamba mwa achikulire omwe ali ndi thupi lolemera zosakwana 60 makilogalamu ndi 50 mg, woposa 60 kg ndi 100 mg × 3 kawiri pa tsiku. Mlingo wapamwamba tsiku lililonse ndi 600 mg.

Kuteteza: koyamba mlingo - 50 mg 1 nthawi patsiku ndi kuwonjezeka pang'onopang'ono kwa limodzi mlingo mpaka 100 mg (kuchuluka kwa mlingo kumachitika kwa miyezi itatu).

Zotsatira zoyipa

Popeza acarbose amalepheretsa kuwonongeka kwa chakudya chamagulu m'thupi la glucose, kuchuluka kwa mafuta ena kumatsalira m'matumbo ndikuperekedwa ku colon. M'matumbo, mabakiteriya amabaya zovuta zam'mimba, zomwe zimayambitsa mavuto am'mimba monga flatulence (78% ya odwala) ndi matenda am'mimba (14% ya odwala). Popeza izi zimadalira mlingo, nthawi zambiri zimalimbikitsidwa kuti muyambe ndi mlingo wochepa ndikuwonjezera pang'onopang'ono mlingo mpaka muyezo womwe mukufuna. Kafukufuku wina adawonetsa kuti zoyipa zam'mimba zimachepa kwambiri (kuchokera 50% mpaka 15%) mkati mwa masabata 24, ngakhale ndikugwiritsa ntchito pafupipafupi.

Wodwala yemwe akugwiritsa ntchito acarbose akuvutika ndi vuto la hypoglycemia, wodwalayo ayenera kudya kena kokhala ndi ma monosaccharides, monga mapiritsi a glucose kapena gel (GlucoBurst, Insta-Glucose, Glutose, Level 1), ndipo dokotala ayenera kuyitanidwa. Chifukwa acarbose chimalepheretsa kuwonongeka kwa shuga wa patebulo ndi shuga ena ovuta, misuzi yazipatso kapena zakudya zosakhazikika sizingasinthe bwino gawo la hypoglycemia wodwala atatenga acarbose.

Hepatitis amadziwika kuti amagwiritsa ntchito acarbose. Nthawi zambiri zimazimiririka mankhwala ukayimitsidwa. Chifukwa chake, ma enzyme a chiwindi amayenera kufufuzidwa musanagwiritse ntchito mankhwalawa.

GIT: kupweteka kwa epigastric, flatulence, nseru, kutsegula m'mimba, kawirikawiri - kuchuluka kwa "chiwindi" transaminases (mukamamwa mlingo wa 150-300 mg / tsiku), kutsekeka kwamatumbo, jaundice, hepatitis (nthawi zina, imatha kufa ndi matenda).

Malangizo apadera Sinthani

Kuchita maopaleshoni akuluakulu komanso kuvulala, kuwotcha kwambiri, matenda opatsirana omwe ali ndi febrile syndrome kungafune kutha kwa mankhwalawa a hypoglycemic mankhwala ndi makonzedwe a insulin. M'pofunika kutsatira mosamalitsa zakudya. Zakumwa ndi zakudya zomwe zimakhala ndi chakudya chamagulu ambiri (poly-, oligo-, disaccharides) zimatha kudzetsa matumbo. Chithandizo chikuyenera kuchitika mothandizidwa ndi shuga m'magazi komanso / kapena mkodzo wa glycosylated Hb ndi transaminases mchaka choyamba chithandizo - kamodzi pa miyezi itatu iliyonse ndipo kenaka. Kuwonjezeka kwa mlingo woposa 300 mg / tsiku kumayendetsedwa ndi kuchepa kwapang'onopang'ono kwa hypprlycemia ya postprandial ndi kuwonjezeka kwamtundu umodzi pachiwopsezo cha hyperfermentemia. Ndi munthawi yomweyo mankhwala - mankhwala a sulfonylurea kapena insulin, kukula kwa hypoglycemia ndikotheka, komwe kumakonzedwa ndikuwonjezera shuga ku chakudya, kapena kudzera m'mitsempha yake yamkati. Pakakhala hypoglycemia yovuta kwambiri, muyenera kukumbukira kuti shuga ya chakudya imang'ambika mu glucose ndi fructose, yomwe siyimayendetsedwa ndi insulin ndipo chifukwa chake sucrose siyabwino kwenikweni chifukwa cha hypoglycemia. Kuti muchotse, ndikofunikira kugwiritsa ntchito shuga m'magawo akulu kapena glucagon (woopsa).

Chitani Harani

Zotumphukira za sulfonylureas, insulin, metformin kumapangitsa mphamvu ya hypoglycemic. Maantacid, colestyramine, adsorbents m'matumbo, mankhwala a enzyme amachepetsa mphamvu. Thiazide diuretics, corticosteroids, phenothiazines, mahomoni a chithokomiro, estrogens, kulera pakamwa, phenytoin, nicotinic acid, adrenostimulants, BMKK, isoniazid ndi mankhwala ena omwe amachititsa hyperglycemia, amachepetsa kwambiri zochitika (zotheka kuwonongeka kwa matenda osokoneza bongo).

Zizindikiro zogwiritsidwa ntchito

Acarbose amalembedwa kwa odwala omwe ali ndi vuto la matenda a shuga a mtundu woyamba kapena 2, komanso kwa omwe ali ndi matenda a prediabetesic omwe ali ndi jakisoni wa insulin.

Kutha kwake kuchepetsa thupi kwatsimikiziridwa mwasayansi, chifukwa chake mankhwalawa amatha kupatsidwa mankhwala onenepa kwambiri, matenda a shuga. Acarbose amalembedwa kwa odwala matenda ashuga omwe amagwira ntchito zolimbitsa thupi, m'malo mwa mankhwala opatsirana ndi sulfonylurea, chifukwa chomaliza nthawi zambiri chimayambitsa hypoglycemia.

Kutulutsa Fomu

Acarbose ndi ufa woyera (mithunzi yopepuka ndiyotheka), yomwe singasungunuke mosavuta m'madzi. M'mafakisi, amamasulidwa monga mapiritsi, ndi mlingo wa 50 ndi 100 mg.

Zina zotchuka kwambiri za acarbose ndi Germany "Glucobay" ndi "Alumina" waku Turkey. Mtengo wapakati woyamba ndi pafupifupi ma ruble 490 a mapiritsi 30 okhala ndi mulingo wa 50 mg. Mankhwala "Glinoza" sanapezeke mumayiko ena aku Russia posachedwapa.

Kutengera mlingo, Glucobai imakhala ndi 50 kapena 100 mg ya acarbose. The achire zotsatira amapezeka m'mimba thirakiti. Imachepetsa ntchito za ma enzymes ena omwe amakhudzidwa ndi kuphwanya kwa polysaccharides.

Mwa zina zowonjezera: silicon dioxide, magnesium stearate, starch ya chimanga, cellcrystalline cellulose.

Malangizo ogwiritsira ntchito

Mankhwala amatengedwa pakamwa Mphindi 15-20 asanadye. Zakudya zotheka mutatha kudya. Pankhaniyi, zidzakhala zofunikira kudikirira ola limodzi.

Mlingo wakhazikitsidwa ndi dokotala aliyense payekha kwa wodwala aliyense, kutengera mkhalidwe wa thanzi lake, kuopsa kwa njira ya matenda ashuga, kupezeka kwa matenda oyanjana.

Monga lamulo, pa gawo loyambirira, kudya katatu kwa 50 mg ndikutchulidwa. Ngati pambuyo pa miyezi 1-2 palibe mavuto omwe adapezeka, mlingo umachuluka.

Chololedwa kutenga zosaposa 600 mg ya acarbose patsiku. Kutalika kwa mankhwala ayenera kukhala osachepera miyezi isanu ndi umodzi.

Zolemba ntchito

Mankhwala okhala ndi acarbose amalephera kugwiritsidwa ntchito ndi ana komanso achinyamata osakwana zaka 18. Ndikulimbikitsidwanso kuti nthawi yayitali ya mankhwalawa musatenge mowa uliwonse chifukwa chosagwirizana ndi chophatikiza.

Odwala okalamba, komanso anthu omwe ali ndi matenda a chiwindi ndi impso, amaloledwa kugwiritsa ntchito mankhwalawa. Sikuti mankhwalawa sayenera kusintha, amasankhidwa malinga ndi kuopsa kwa njira ya matenda ashuga komanso momwe thupi limayankhira pakuchiritsa.

Acarbose amaletsedwa panthawi yonse ya kubereka komanso mkaka wa m'mawere chifukwa cha kusowa kwa umboni wa sayansi za chitetezo chake kwa mwana wosabadwayo.

Kuchita ndi mankhwala ena

Mankhwala okhala ndi acarbose amalimbikitsa zochita za metformin, insulin, sulfonylurea, potero zimathandizira kukulitsa kwambiri hypoglycemia.

Mwa zina mwa mankhwala omwe amachepetsa mphamvu ya mankhwala, awa:

• mahomoni a chithokomiro,
• mankhwala a antiidal
• okodzetsa
• kulera
• mankhwala okhala ndi nicotinic acid.

Kuphatikiza kwa hypoglycemic mankhwala osokoneza bongo sikuyenda bwino chifukwa chakufooka kwa chithandizo chamankhwala chomaliza.

Zotsatira zoyipa

Mankhwala ozikidwa pa acarbose angayambitse mayankho osafunikira a thupi pakuchiritsa. Nthawi zambiri kuposa zomwe ena amakhala:

• kupangika kwamagesi kwambiri, kutsekula m'mimba, kupweteka pamimba,
• kutsekeka kwathunthu kapena pang'ono,
• kuchuluka kwa chiwindi michere.

Kuchokera pakhungu, ming'oma, zotupa zimatha kuwoneka.

Monga lamulo, mankhwalawa amalekeredwa bwino. Zotsatira zosafunikira zimawonekera kokha m'masiku oyamba a chithandizo ndikudziyendetsa zokha. Kusintha kwa Mlingo ndi chithandizo chofunikira sichofunikira.

Komabe, kwa nthawi yayitali ya acarbose mankhwala, odwala amalangizidwa kuti aziwunika magazi pafupipafupi kuti awone kuchuluka kwa ma enzymes a chiwindi kuti apewe chiwindi.

Contraindication

Contraindication pakutenga acarbose amatha kugawidwa mu mtheradi ndi wachibale.

Mtheradi wathu ndi awa:

• mimba
• nyere
• matenda ammbuyo
• ketoacidosis
• kulephera kwa aimpso,
• tsankho ku chinthu chilichonse cha mankhwalawa.

Pakati pa wachibale, titha kusiyanitsa:

• malungo
• matenda pambuyo opaleshoni njira.

Ndizofunikira kudziwa kuti ndi dokotala wokhawo yemwe angapange chisankho chomaliza pa mankhwala acarbose.

Bongo

Ngati mlingo woyikirayo udakwaniritsidwa, kutsegula m'mimba ndi kusefukira kumatha kuonekera. Potere, wodwalayo ayenera kukana chakudya chopatsa mphamvu kwa maola osachepera asanu.

Zizindikiro zofananira zimatha kuchitika mukamadya chakudya chambiri nthawi ya mankhwala.

Ngati acarbose ikuphatikizidwa pamodzi ndi mankhwala ena ochepetsa shuga, ngozi ya hypoglycemia imakulanso. Mtundu wofatsa wa kupsinjika kotero umayimitsidwa ndi chakudya chamafuta. Mitundu yapakatikati ndi yolemetsa imafunika kulowererapo. Njira yothetsera yomwe amagwiritsidwa ntchito kwambiri ndi dextrose wamkati.

Mwa zokonzekera zochokera ku acarbose, "Glucobay" waku Germany ndi "Glinoza" waku Turkey akuimiridwa pamsika waku Russia. Zotsirizirazi sizachilendo mu maunyolo a pharmacy.

Mankhwala okhala ngati Metformin ali ndi zotsatira zofanana za hypoglycemic. Mayina odziwika kwambiri a malonda ndi Glucophage ndi Siofor.

Nthawi zina, mankhwalawa amachokera ku sulfonylurea: Gliclazide, Glibenclamide

Pambuyo pa zaka 45, shuga wanga wamagazi adayamba kuchuluka. Zakudya sizinathandize. Dokotalayo adapereka mankhwala othandizira. Zophatikiza za metformin zimachepetsa kwambiri shuga, nthawi ina ngakhale kuyitanitsa ambulansi. Tsopano ndikuvomereza Acarbose. Ndikumva bwino, sindinapeze zotsatira zoyipa zilizonse.

Njira yanga yothandizira odwala matenda ashuga ndi yayitali kwambiri. Ndidayesa mankhwala ambiri. Ena sanakwanitse nthawi yomweyo, ena anawonetsa zovuta zawo, patapita nthawi. Tsopano ndimamwa Glucobay. Ndili wokondwa ndi mtengo wake komanso momwe amachepetsera shuga m'magazi anga. Ndikhulupirira kuti alibe zotsatira zoyipa m'thupi mwanga.

Mankhwala amakono satha kuchiritsa matenda ashuga kwathunthu. Ntchito yawo yayikulu ndikusunga kuchuluka kwa shuga m'milingo yovomerezeka ndikupewa kudumphadumpha mmwamba ndi pansi. Odwala omwe ali ndi matenda ashuga ayenera kukumbukira chinthu chachikulu - popanda kudya kwambiri, palibe mankhwala omwe angagwire ntchito, ziribe kanthu momwe ziliri masiku ano.

Kodi acarbose ndi ntchito bwanji?

Zakudya zomanga thupi zomwe zili m'zakudya zathu ndizovuta kwambiri. Mukangolowa m'mimba, amadzidula hydrolysis ndi michere yapadera - glycosidases, pambuyo pake amawola monosaccharides. Mashuamu osavuta, amadzalowa m'matumbo mucosa ndikulowa m'magazi.

Acarbose mu kapangidwe kake ndi pseudosaccharide wopezeka ndi njira ya biotechnological. Imachita mpikisano ndi mashuga kuchokera ku chakudya m'matumbo apamwamba: imamangiriza ma enzyme, kuwakankhira kwakanthawi mwayi wokhoza kugwetsa chakudya. Chifukwa cha izi, acarbose imachedwetsa magazi kulowa m'magazi. Glucose wocheperako komanso wolumikizana kwambiri amalowa m'matumba, momwe amachichitira bwino. Glycemia imakhala yotsika, kusinthasintha kwake mukatha kudya kumachepetsedwa.

Zotsimikizika Acarbose Zotsatira:

1. Naturalizing glycated hemoglobin, bwino kubwezeretsa kwa shuga.
2. Ndi kuphwanya komwe kulipo kwa kulolera kwa shuga ndi 25% kumachepetsa chiopsezo chokhala ndi matenda ashuga.
3. Zimalepheretsa matenda a mtima: chiwopsezo chimachepetsedwa ndi 24% odwala matenda ashuga, ndi 49% mwa odwala NTG.

Acarbose imakhala yothandiza kwambiri kwa odwala omwe ali ndi kudya mwachangu glycemia komanso okwera atatha kudya. Kafukufuku awonetsa kuti kugwiritsidwa ntchito kwake kumatha kuchepetsa kuthamanga kwa glucose ndi 10%, shuga atatha kudya ndi 25%, hemoglobin wa glycated ndi 21%, cholesterol ndi 10%, triglycerides ndi 13%.Pamodzi ndi glycemia, kuchuluka kwa insulin m'mwazi kumachepa. Chifukwa chotsika cha insulin ndi lipids mwa odwala omwe ali ndi matenda ashuga, kukana insulini komanso chiopsezo cha atherosulinosis kumachepetsedwa, kuchepa thupi kumathandizidwa.

Acarbose wagwiritsidwa ntchito ngati hypoglycemic kwazaka zopitilira 20. Ku Russia, ndi mankhwala amodzi okha omwe ali ndi mankhwalawa omwe adalembetsa - Glucobai ku kampani yaku Germany ya Bayer Pharma. Mapiritsiwo ali ndi 2 Mlingo - 50 ndi 100 mg.

Kugwiritsa ntchito Acarbose Glucobai pakuchepetsa thupi

Mukamamwa ma acarbose, ena mwa zakudya zamafuta alibe nthawi yophulika ndipo amachotsedwa m'thupi ndi ndowe, ndipo zopatsa mphamvu za calorie zimachepetsedwa. Adayesera kugwiritsa ntchito nyumbayi mochulukira kamodzi kuti achepetse thupi, ngakhale maphunziro adachitidwa pakugwiritsa ntchito mankhwalawa kuti achepetse thupi. Odwala omwe ali ndi matenda ashuga, kuyambitsidwa kwa acarbose mu regimen yamankhwala kumapangitsa kuti muchepetse kulemera kwa 0,4 kg. Nthawi yomweyo, caloric kudya komanso kuchuluka kwa mitolo idakhalabe yomweyo.

Doctor of Medical Science, Mutu wa Institute of Diabetesology - Tatyana Yakovleva

Ndakhala ndikuphunzira matenda a shuga kwa zaka zambiri. Zimakhala zowopsa anthu ambiri akamwalira, ndipo makamaka amakhala olumala chifukwa cha matenda ashuga.

Ndithamangira kunena mbiri yabwino - Endocrinological Research Center ya Russian Academy of Medical Science idatha kupanga mankhwala omwe amachiritsiratu matenda ashuga. Pakadali pano, kugwiritsa ntchito bwino kwa mankhwalawa kuyandikira 98%.

Nkhani ina yabwino: Unduna wa Zaumoyo wateteza kukhazikitsidwa kwa pulogalamu yapadera yomwe imalipira mtengo wa mankhwalawo. Ku Russia, odwala matenda ashuga mpaka Meyi 18 (kuphatikiza) nditha kuipeza - Kwa ma ruble 147 okha!

Zinapezekanso kuti kugwiritsa ntchito Acarbose pakuchepetsa thupi ndizothandiza kwambiri kuphatikiza ndi zakudya komanso masewera. Pano, phunziroli linkachitika mwa anthu athanzi. Zotsatira zake zinali zolimbikitsa: kupitirira miyezi 5, odwala adachepetsa BMI yawo ndi 2.3, pagulu lolamulira popanda acarbose - 0,7 yokha. Madokotala amati izi zimachitika chifukwa cha mankhwalawa. Akayamba kuchepa thupi ndi chakudya chambiri, nthawi yomweyo amalimbitsa machitidwe a nayonso mphamvu m'matumbo, flatulence kapena m'mimba akuyamba. Acarbose pano amachita ngati chisonyezo cha chakudya choyenera, kuphwanya kulikonse kwa zakudya kumakhala ndi zotsatirapo zosasangalatsa.

Zitha kusintha

Glucobai ilibe mndandanda wathunthu. Kuphatikiza pa acarbose, gulu la cy-glucosidase inhibitors limaphatikizanso zinthu zomwe zimagwira monga voglibose ndi miglitol. Pamaziko awo, German Diastabol, Turkey Alumina, Ukraine Voksid adapangidwa. Amakhala ndi zofanana, motero amatha kuwonedwa ngati fanizo. Muzipatala za ku Russia, palibe mankhwala omwe amaperekedwa, kuti odwala matenda ashuga azikhala okha ku Glucobai kapena abweretse mankhwala ochokera kunja.

Acarbose sanaphatikizidwe pamndandanda wa mankhwala osokoneza bongo a Vital and Essential, kotero odwala omwe ali ndi matenda ashuga amakakamizidwa kugula Glucobay okha. Mtengo ku Russia umachokera ku 500 mpaka 590 rubles. mapiritsi 30 a 50 mg. Mlingo wa 100 mg ndiwotsika mtengo pang'ono: ma ruble 650-830. kuchuluka komweko.

Pafupifupi, chithandizo chidzafunika ma ruble 2200. kwa mwezi. M'masitolo ogulitsa pa intaneti, mankhwalawa ndi otsika mtengo pang'ono, koma ambiri mwaiwo mumayenera kulipira mukamapereka.

Ndemanga za Odwala

Malinga ndi anthu odwala matenda ashuga, Glucobai ndi mankhwala "osasangalatsa". Odwala amakakamizidwa kuti azingotsatira zakudya zamafuta ochepa, koma nthawi zina kusiya zamkaka, chifukwa lactose imathanso kubweretsa zovuta m'matumbo. Mphamvu yotsitsa shuga ya acarbose imawunikidwa bwino. Mankhwala amatha kusintha shuga pambuyo pakudya, amachepetsa kusinthasintha kwake masana.

Ndemanga kuchepetsa thupi sikuyembekeza kwenikweni. Amamwa mankhwalawa makamaka mano okoma, omwe sangachite popanda mchere kwa nthawi yayitali. Amapeza mapiritsiwo kukhala osavulaza, koma okwera mtengo kwambiri. Kuphatikiza apo, chifukwa cha zovuta, zakudya zamatumbo zimatha kudyedwa kunyumba, osawopa zotsatira zake. Poyerekeza ndi Xenical, Glucobay imalekeredwa bwino, koma zotsatira zake ndizochepa.

Onetsetsani kuti mwaphunzira! Kodi mukuganiza kuti kuyamwa kwa mapiritsi ndi insulini kwa nthawi yonse yokhayo ndi njira yokhayo yosungira shuga m'manja? Sichowona! Mutha kutsimikizira izi nokha ndikuyamba kuzigwiritsa ntchito. werengani zambiri >>