Tricor 145 mg: malangizo ogwiritsira ntchito, ma analogi ndi ndemanga, mitengo yama pharmacies aku Russia

Tricor ndi mankhwala a hypolipidemic omwe ali ndi uricosuric ndi antiplatelet. Amachepetsa cholesterol yonse ya magazi ndi 20-25%, magazi a TG ndi 40-45% ndi uricemia ndi 25%. Zomwe zimagwira ndi Fenofibrate.

Amachepetsa magazi triglycerides ndi (mochepera) cholesterol. Zimathandizira kuchepetsa zomwe zili mu VLDL, LDL (mpaka pang'ono), kuwonjezera zomwe zili anti-atherogenic HDL. Njira zomwe amagwirira ntchito sizomveka bwino.

Zotsatira pamlingo wa TG zimagwirizanitsidwa makamaka ndi kuyambitsa kwa enzyme lipoprotein lipase. Zikuwoneka kuti fenofibrate imasokoneza kaphatikizidwe wamafuta acids, imathandizira kuwonjezeka kwa kuchuluka kwa LDL receptors m'chiwindi, kusokoneza kaphatikizidwe ka cholesterol.

Pa maphunziro azachipatala, zidadziwika kuti kugwiritsa ntchito Tricor kumachepetsa cholesterol yonse ndi 20-25% ndi triglycerides ndi 40-55% ndikuwonjezeka kwa HDL-C ndi 10-30%. Odwala omwe ali ndi hypercholesterolemia, momwe mulingo wa Chs-LDL amachepetsedwa ndi 20-35%, kugwiritsa ntchito fenofibrate kunapangitsa kutsika kwa ziwerengero: chonse Chs / Chs-HDL, Chs-LDL / Chs-HDL ndi apo B / apo AI, omwe ali chizindikiro cha chiopsezo cha atherogenic.

Pogwiritsa ntchito mankhwalawa, zowonjezera zowonjezera za cholesterol (tendon ndi tuberous xanthomas) zimatha kuchepa kwambiri komanso zimatha.

Ubwino wina kwa anthu omwe ali ndi hyperuricemia ndi dyslipidemia ndi mphamvu ya uricosuric yogwira ntchito, yomwe imayambitsa kuchepa kwa kuchuluka kwa uric acid ndi pafupifupi 25%.

Pali umboni wa kuchepa kwa kuphatikiza kwa maselo othandiza magazi kuundana chifukwa cha adenosine diphosphate, epinephrine ndi arachidonic acid.

Zizindikiro zogwiritsidwa ntchito

Kodi chimathandiza ndi chiyani Tricor? Malinga ndi malangizo, mankhwalawa amalembedwa motere:

Hypercholesterolemia ndi hypertriglyceridemia otalikirana kapena osakanikirana (dyslipidemia mtundu IIa, IIb, III, IV, V) ndi kusagwira bwino kwa njira zosagwiritsa ntchito mankhwala (kuchepa thupi, kuchuluka kwa zochitika zolimbitsa thupi), makamaka pakakhala vuto lomwe limadza chifukwa cha dyslipidemia - ochepa matenda oopsa komanso kusuta,
Hyperlipoproteinemia yachiwiri, mu nthawi yomwe hyperlipoproteinemia imapitiliza, ngakhale chithandizo chazomwe chimayambitsa matenda (mwachitsanzo, dyslipidemia mu shuga mellitus).

Mankhwalawa adapangidwa kuti aphatikizidwe ndi mafuta a cholesterol komanso monga gawo la zovuta mankhwala.

Malangizo ogwiritsira ntchito Tricor 145 mg, mlingo

Piritsi ya Tricor 145 mg imatengedwa pakamwa, mosasamala kanthu ndi chakudya (chonsecho), chosambitsidwa ndi madzi oyera. Mankhwala Mlingo wa 160 mg amatengedwa ndi chakudya.

Mlingo wofanana, mogwirizana ndi malangizo ogwiritsira ntchito, piritsi limodzi la Tricor 145 mg 1 nthawi patsiku. Mankhwala ndi mankhwala kwa nthawi yayitali, mukudya.

Mlingo wa ana wakhazikitsidwa ndi adotolo, muyezo womwewo umawerengeredwa potengera kulemera kwa mwana - 5 mg / kg patsiku.

Odwala omwe amatenga piritsi limodzi la Fenofibrate 160 mg 1 nthawi patsiku amatha kusinthira kutenga TRICOR 145 mg popanda kusintha kwa mlingo wowonjezera.

Okalamba safuna kusintha kwa mlingo. Ndi kulephera kwa aimpso, mlingo wochepetsedwa umayikidwa.

Malangizo apadera

Pakakhala zosakhutiritsa kwenikweni, pakatha miyezi 3-6 kumwa mankhwalawo, concomitant kapena njira zina zitha kutumikiridwa.

Ndikulimbikitsidwa kuyang'anira ntchito ya "hepatic" transaminases miyezi itatu iliyonse mchaka choyamba chothandizira, kupuma kwakanthawi ngati chithandizo chawo chikuwonjezeka, komanso kuphatikizidwa kwa mankhwala a hepatotoxic kuchokera munthawi yomweyo.

Mwa anthu omwe ali ndi hyperlipidemia omwe amathandizidwa ndi mankhwala a estrogen kapena amatenga njira yoletsa kubereka pakamwa, kuphatikiza ma estrogens, choyambirira kapena chachiwiri cha kupangika kwa hyperlipidemia ziyenera kutsimikiziridwa, chifukwa kuwonjezeka kwa milomo ya lipid ndikotheka chifukwa cha kudya kwa estrogens.

Zotsatira zoyipa

Malangizowa amachenjeza za mwayi wokhala ndi zotsatirapo zoyipa potsatira Tricor:

Lymphatic / circulatory system: kawirikawiri - kuwonjezeka kwa zomwe zimakhala m'magazi oyera ndi hemoglobin,
Matumbo: Nthawi zambiri - kupweteka kwam'mimba, kusanza, kusanza, kutsekemera komanso kutsegula m'mimba pang'ono, nthawi zina - milandu ya kapamba,
Matenda a minofu ndi mafupa ofunikira: kawirikawiri - myositis, kufalitsa myalgia, kufooka, minofu kukokana, kawirikawiri - rhabdomyolysis,
Chiwindi: pafupipafupi - kuwonjezeka kwapang'onopang'ono kwa kuchuluka kwa ma seramu transaminases, nthawi zina - mapangidwe a gallstones, osowa kwambiri - ma episode a hepatitis (muzochitika zamankhwala - jaundice, kuyabwa - mayeso a labotale amafunika, milandu yotsimikizira,
Machitidwe amsempha: kawirikawiri - kupweteka mutu, kukomoka,
Mtima dongosolo: nthawi zina - venous thromboembolism (kwambiri mtsempha thrombosis, pulmonary embolism),
Khungu ndi subcutaneous mafuta: Nthawi zina - kuyabwa, zidzolo, photosensitivity, urticaria, kawirikawiri - alopecia, kawirikawiri - zithunzi zam'mimba zomwe zimachitika ndi erythema, mapangidwe a timinofu kapena matuza m'malo a khungu ovumbulutsidwa ndi radiation ya UV kapena kuwala kwa dzuwa (mu m'malo mwanu - mutagwiritsidwa ntchito kwa nthawi yayitali popanda zovuta zina,
Kupuma: kawirikawiri - pneumopathy,
Maphunziro a Laborator: nthawi zina - kuchuluka kwa urea ndi creatinine mu seramu.

Contraindication

Amatsutsana kuti apereke Tricor pazotsatirazi:

Matenda owopsa a chiwindi, limodzi ndi ziwalo zolala,
Kulephera kwa chiwindi
Kulephera kwakukulu kwaimpso,
Pachimake kapamba kapena pancreatitis yayikulu,
Matenda a ndulu ndi kuchepa kwake,
Mimba komanso kuyamwa,
Osakwana zaka 18
Munthu payekha hypersensitivity pamagawo a mankhwala.

Amasankhidwa mosamala kwa anthu omwe ali ndi hepatic ndi / kapena kulephera kwa aimpso, chifukwa cha hypothyroidism, odwala omwe amamwa mowa, odwala okalamba, omwe ali ndi mbiri yamatenda amtundu wamtundu, pomwe akumamwa anticoagulants, HMG-CoA reductase inhibitors.

Bongo

Zizindikiro zopitirira muyeso sizinafotokozedwe mu malangizo. Palibe zachipatala zomwe zimapezeka paliponse pa mankhwala osokoneza bongo.

Mankhwalawa sakudziwika. Mankhwalawa ndi chizindikiro. Hemodialysis siyothandiza.

Ma Analogs a Tricor, mtengo pama pharmacies

Ngati ndi kotheka, mutha kusintha Tricor ndi analogue yogwira ntchito - awa ndi mankhwala:

Fenofibrate Canon (kuchokera kuma ruble 320.90),
Lipantil (kuchokera pa 845.00 rub),
Lipantil 200 M (kuchokera ma ruble 868.80).

Zofanana muzochita:

Mukamasankha analogues, ndikofunikira kumvetsetsa kuti malangizo ogwiritsira ntchito Tricor 145 mg, mtengo ndi ndemanga sizigwira ntchito ndi mankhwala omwewo. Ndikofunikira kupeza upangiri wa dokotala komanso kuti usasinthe popanda mankhwala.

Mtengo m'mafakitale ku Moscow ndi Russia: Mapiritsi a Tricor 145 mg 30 - kuchokera ku ma 864 mpaka 999 ma ruble, malinga ndi mafakitale a 729.

Sungani pamalo owuma pamatenthedwe mpaka 25 ° C. Pewani kufikira ana. Moyo wa alumali ndi zaka zitatu.

Zoyenera kufalitsa kuchokera ku mafakitala zimalembedwa ndi mankhwala.

Ndemanga zitatu za "Tricor 145 mg"

Tricor 145 sanandiyenereze, nditatenga miyezi iwiri, ululu wa paresis wa thupi unakulirakulira, kufooka kwa minofu yonse (ndinadwala matenda a hemorrhagic zaka 8 zapitazo, mbali zamanja zolimbikira zikupitilira tsopano) Palibe kusintha komwe kumawonedwa, kufooka kowopsa mthupi lonse komanso ulesi.

Zotsatira za mankhwalawa zimamveka. Zovuta zina mthupi lonse. Mapeto a phwando, zonse zimadutsa. Zotsatira zomwe, mothandizidwa ndi Tricorr, ndidayenera kuzikwaniritsa - ndakwaniritsa. Kubwereza kwa hemophthalmus (mtsempha wa magazi mkati mwa hemorrhage) kunali kupewedwa

Sindinathetse chidaliro m'mapiritsi awa - panthawi ya utsogoleri, sizimamveka bwino.

Kutulutsa mawonekedwe ndi kapangidwe kake

Tricor akupezeka mu mitundu yotsatsira iyi:

mapiritsi okhala ndi kanema, 145 mg: oblong, oyera, wokhala ndi chizindikiro cha kampani mbali imodzi ya cholembapo ndipo mawu akuti "145" mbali inayo (ma PC 10. mumatumba, mu katoni 1, 2, 3, 5, 9 kapena 10 matumba, ma PC 14, m'matumba, m'matumba ofunika 2, 6 kapena 7, kuzipatala - ma PC 10 m'matumba, pamatoni a makatoni 28 kapena 30 matuza),
mapiritsi okhala ndi kanema, 160 mg: oblong, oyera, ali ndi dzina la kampani mbali imodzi ya cholembapo ndipo mawu akuti "160" mbali inayo (ma PC 10. mumatumba, mu katoni 1, 2, 3, 4, 5, 9 kapena matuza 10, ma PC 14 mu matuza, pakatakata 2, 6 kapena 7 matuza.

Paketi iliyonse ilinso ndi malangizo ogwiritsira ntchito Tricor.

Zopangidwira pa piritsi yokutira filimu:

yogwira mankhwala: fenofibrate (yojambulidwa mwanjira ya nanoparticles) - 145 mg kapena 160 mg,
othandizira zigawo zikuluzikulu: sodium lauryl sulfate, sodium stearyl fumarate, crospovidone, colloidal silicon dioxide, docusate sodium, sucrose, lactose monohydrate, microcrystalline cellulose, hypromellose, magnesium stearate, povidone,
filimu sheath: Opadry OY-B-28920 (titaniyamu dioksidi, talc, xanthan chingamu, mowa wa polyvinyl, soya lecithin).

Mankhwala

Fenofibrate amatanthauza zochokera ku fibroic acid. Njira yamachitidwe ake imalumikizidwa ndi kutsegula kwa RAPP-alpha (alpha receptors yoyesedwa ndi proxisome proliferators). Chifukwa cha kutsegula kwa RAPP-alpha, lipolysis ya lipoproteins ya atherogenic imalimbikitsidwa ndipo kutulutsa kwawo kuchokera ku plasma kwathandizira. Izi zimatithandizanso kuwonjezeka pakuphatikizidwa kwa ma apoproteins A-1 ndi A-2 (Apo A-1 ndi Apo A-2). Zotsatira zake, izi zomwe zimapezeka m'magawo a LDL (lipensitroteins otsika kwambiri) ndi VLDL (kachulukidwe kakang'ono kwambiri lipoprotein) zimachepetsedwa ndipo zomwe zili mu gawo la HDL (high density lipoprotein) zikuchulukitsidwa. Fenofibrate imachulukitsa kuchuluka kwa LDL excretion ndikuchepetsa zomwe zimakhala zazing'ono ndi zowonda za LDL, kuchuluka komwe kumawonedwa mwa odwala omwe ali ndi atherogenic lipid phenotype (makamaka nthawi zambiri, zovuta zotere zimachitika mwa anthu omwe ali pachiwopsezo cha matenda a mtima a coronary).

Zotsatira zamaphunziro azachipatala, zidawonetsedwa kuti fenofibrate imachepetsa kuchuluka kwa triglycerides ndi 40-55% ndi cholesterol yathunthu ndi 20-25% ndi kuwonjezeka kwa cholesterol ndi HDL ndi 10-30%. Odwala omwe ali ndi hypercholesterolemia yotsika cholesterol ndi LDL (pofika 20- 35%) panthawi yogwiritsa ntchito fenofibrate, mitundu yotsatirayi ya mankhwalawa imachepa: "LDL-cholesterol / HDL-cholesterol", "whole cholesterol / HDL-cholesterol", "Apo B / Apo A-1 "(zigawo zomwe zalembedwa ndizizindikiro za chiopsezo cha atherogenic).

Popeza Tricor amakhudza kwambiri kuchuluka kwa triglycerides ndi LDL cholesterol, kugwiritsidwa ntchito kwake mu hypercholesterolemia, motsatana osatsatiridwa ndi hypertriglyceridemia (mwachitsanzo, hyperlipoproteinemia mwachitsanzo, mtundu 2 shuga mellitus).

Pogwiritsa ntchito fenofibrate, kuchepa kwakukulu komanso ngakhale kuzimiririka kwathunthu kwa zowonjezera za cholesterol (tuberous ndi tendon xanthomas) ndizotheka. Mwa anthu omwe ali ndi fibrinogen yayikulu, kuchepa kwakukulu kwa chizindikirochi kumawonedwa mchikakamizo cha fenofibrate (monga odwala omwe ali ndi kuchuluka kwa lipoproteins). Mlingo wa chizindikiro china cha kutupa, C-yogwira mapuloteni, imacheperanso ndi mankhwala a fenofibrate.

Mwa zina, Tricor amakhala ndi uricosuric kwambiri ndipo amachepetsa kuchuluka kwa uric acid pafupifupi 25%, yomwe ndi mwayi wina kwa odwala omwe ali ndi hyperuricemia ndi dyslipidemia.

Poyesera nyama, komanso poyesa mankhwalawa, adawonetsedwa kuti amachepetsa kuphatikiza kwa ma cell chifukwa cha epinephrine, arachidonic acid ndi adenosine diphosphate.

Pharmacokinetics

Mapiritsi a Tricor mu Mlingo wa 160 mg ali ndi bioavailability apamwamba kuposa mitundu yoyambira ya fenofibrate.

Kuchuluka kwa plasma ndende kumachitika pambuyo 2-5 maola (mapiritsi a 145 mg) kapena maola 4-5 (mapiritsi a 160 mg). Sizitengera kudya kwakanthawi komanso kugwiritsa ntchito mankhwalawa kwa nthawi yayitali amakhazikika mosasamala kanthu za wodwala.

Mutatenga Tricor, fenofibrate yoyambirira m'madzi a m'magazi samapezeka. Imachulukitsidwa ndi ma esterases. Pulma metabolite wamkulu wa mankhwalawa ndi fenofibroic acid, woposa 99% womanga mapuloteni a plasma (albumin). Fenofibrate sachita nawo microsomal metabolism ndipo si gawo laling'ono la CYP3A4 enzyme.

Hafu ya moyo ndi pafupifupi maola 20. Njira yayikulu yotsira ndi mkodzo (mu mawonekedwe a conjugate ya glucuronide ndi fenofibroic acid). Fenofibrate imatsala pang'ono kuthetsedwa mkati mwa masiku 6. Mwa anthu okalamba, kutsimikizika kwathunthu kwa fenofibroic acid sikusintha.

Zotsatira zake zimachitika pang'onopang'ono kamodzi kwa mankhwala, komanso chifukwa chogwiritsa ntchito nthawi yayitali. Hemodialysis yochotsa fenofibrate ndiyosatheka (chifukwa chomangika kwambiri pamapuloteni a plasma).

Contraindication

Kulephera kwa impso kwamtundu uliwonse,
zikuwonetsa mbiri ya matenda a ndulu,
Kulephera kwa chiwindi (kuphatikiza hepatitis yosatha ya chiyambi chosadziwika komanso cilir cirrhosis),
pachimake kapena matenda kapamba, pokhapokha ngati pali chifuwa chachikulu cha pancreatitis chifukwa cha hypertriglyceridemia,
mbiri ya batala la peanut, soya lecithin, mtedza kapena zogwirizana ndi mankhwala mu anamnesis (chifukwa cha chiwopsezo cha hypersensitivity),
lactase enzyme akusowa, kobadwa nako galactosemia, kuperewera kwa galactose ndi glucose (popeza mapiritsi ali ndi lactose),
kusowa kwa isomaltase / sucrase enzyme, kobadwa nako fructosemia (popeza sucrose ndi gawo la mapiritsi),
mbiri ya Phototoxicity kapena photosensitization pa mankhwalawa a ketoprofen kapena ma fiber,
kuyamwa
ana ndi achinyamata osakwana zaka 18,
Hypersensitivity kuti fenofibrate, komanso zigawo zina za mankhwala.

Wachibale (Tricor amagwiritsidwa ntchito mosamala):

hypothyroidism
mbiri yakuwala yamatenda amisempha,
The munthawi yomweyo hydroxymethylglutaryl coenzyme A reductase inhibitors (HMG-CoA reductase) kapena anticoagulants mkamwa,
uchidakwa
ukalamba
nthawi ya pakati.

Tricor: malangizo ogwiritsira ntchito (Mlingo ndi njira)

Tricor iyenera kumwedwa pakamwa, ngakhale nthawi yakudya. Piritsi liyenera kumezedwa lonse popanda kutafuna, kutsukidwa ndi madzi okwanira.

Amafunikira kupitiliza kutsatira zakudya zapadera za hypocholesterolemic, zomwe zimayikidwa musanayambe mankhwala ndi mankhwala.

Mlingo womwe umalimbikitsa ndi piritsi limodzi (145 mg kapena 160 mg) kamodzi patsiku. Odwala omwe m'mbuyomu adatenga fenofibrate m'mapiritsi a 200 mg kapena mapiritsi a 160 mg, kapisozi imodzi kapena piritsi limodzi kamodzi patsiku, amatha kusintha piritsi limodzi la Traicor 145 mg kapena 160 mg popanda kusintha kwa mlingo wina.

Kwa anthu achikulire (ndi aimpso wabwinobwino), mankhwalawa amapatsidwa mankhwala osokoneza bongo.

Mphamvu ya chithandizo iyenera kuyesedwa ndi kuchuluka kwa triglycerides, cholesterol ndi LDL mu seramu.Ngati patadutsa miyezi ingapo ya chithandizo (nthawi zambiri pambuyo pa miyezi itatu) palibe zotsatira zake, ndikofunikira kusankha pazomwe mankhwalawo angagwiritsire ndikuwapatseni mankhwala ena.

Zotsatira zoyipa

Zotsatira zoyipa za Traicor zomwe zapezeka ndimayeso oyendetsedwa ndi placebo:

zam'mimba dongosolo, chiwindi ndi biliary dongosolo: Nthawi zambiri - Zizindikiro ndi matenda am'mimba (kusanza, nseru, m'mimba, flatulence, kutsegula m'mimba), kuchuluka kwa chiwindi, infrequent - cholelithiasis, kapamba, kawirikawiri - hepatitis,
mtima dongosolo: pafupipafupi - mitsempha yakuya ya m'munsi malekezero, pulmonary thromboembolism,
mantha dongosolo: pafupipafupi - mutu, kawirikawiri - chizungulire, kuchuluka kutopa,
minofu: Mafupa a minofu (minositis, kufooka kwa minofu, kupweteka kwa myalgia, kuphipha kwa minofu),
kubereka: mosasimbika - kusabala,
Mitsempha yamagazi ndi magazi: kawirikawiri - kuchepa kwa hemoglobin, kuchepa kwa maselo oyera,
chitetezo chamthupi: kawirikawiri - hypersensitivity,
khungu ndi mafuta ozungulira: pafupipafupi - zidzolo, kuyabwa, urticaria, kawirikawiri - zithunzi, kutayika kwa tsitsi,
zasayansi mayeso: pafupipafupi - kuchuluka kwa seramu creatinine, kawirikawiri - kuchuluka kwa magazi urea nayitrogeni ndende.

Zotsatira zoyipa za Traicor zojambulidwa panthawi yogulitsa pambuyo:

chiwindi ndi biliary thirakiti: mavuto a cholelithiasis (cholangitis, cholecystitis, biliary colic), jaundice,
kupuma dongosolo: interstitial m'mapapo matenda,
minofu ndi mafupa: rhabdomyolysis,
khungu ndi mafuta amkati am'mimba: khungu limakhudzidwa (poizoni wa epermal necrolysis, erythema multiforme).

Malangizo apadera

Musanayambe fenofibrate, ndikofunikira kuchitira chithandizo choyenera kuti muchepetse chifukwa cha yachiwiri ya hypercholesterolemia m'matenda monga hypothyroidism, dysproteinemia, mtundu wosalamulira 2 shuga mellitus, nephrotic syndrome, matenda oopsa a chiwindi, komanso zakumwa zoledzeretsa.

Odwala omwe ali ndi hyperlipidemia, kutenga estrogen okhala ndi mahomoni oletsa kubereka kapena estrogens, kuchuluka kwa lipid kungakhale chifukwa cha estrogen, chifukwa chake, ndikofunikira koyamba kudziwa mtundu wa hyperlipidemia (pulayimale kapena sekondale).

M'chaka choyamba, miyezi itatu iliyonse komanso nthawi yanthawi yamankhwala ena, timalimbikitsidwa kuwunika ma enzymes a chiwindi. Pakuwonjezereka kwa ntchito ya transaminases kuchulukitsa katatu poyerekeza ndi VGN (malire apamwamba), makonzedwe a Tricor ayenera kusiyidwa. Kwa zizindikiro za hepatitis, kuyesedwa koyenera kwa labotale kuyenera kuchitidwa ndipo, ngati matendawo atsimikiziridwa, siyani mankhwalawo.

Chimodzi mwazotsatira za fenofibrate ndikokula kwa kapamba, zomwe zimayambitsa zomwe zimayambitsa kukhudzana mwachindunji ndi Tricor, kusakwanira kwa mankhwala osokoneza bongo kwa odwala omwe ali ndi vuto lalikulu la hypertriglyceridemia, zotsatira zachiwiri (kukoka kapena kupezeka kwa miyala mu ducts ya bile, ndikupanga kusokonezeka kwa duct ya bile).

Chiwopsezo cha rhabdomyolysis pa mankhwala osokoneza bongo chikuwonjezeka mwa odwala omwe ali ndi mbiri yolephera aimpso kapena hypoalbuminemia. Zizindikiro zakupweteka kwa minofu ya m'mimba (myositis, kuphatikiza myalgia, kukokana, minofu kukokana, kuwonjezeka kwa kuchuluka kwa phosphokinase mopitilira kasanu poyerekeza ndi VGN), mankhwala a fenofibrate ayenera kuyimitsidwa.

Kukhazikika kwa munthawi yomweyo kwa Tricor ndi ma fiber ena kapena HMG-CoA reductase inhibitors kumawonjezera mwayi wamavuto owopsa m'misempha, makamaka ngati wodwalayo anali ndi matenda a minofu asanalandire chithandizo. Pachifukwachi, kugwiritsa ntchito mankhwalawa kuphatikizidwa ndi ma statins ndikololedwa kokha ngati matenda osakanikirana a dyslipidemia ndi chiwopsezo chowonjezeka cha mtima wa mtima ndi odwala omwe ali ndi mbiri yamatenda a minofu, komanso kuyang'aniridwa koyang'anitsitsa komwe kumathandizira kudziwa zizindikiro zoyipa za minofu yowonongeka.

Ngati munthawi ya mankhwalawa ndende ya creatinine imadzuka ndi zoposa 50% kuchokera ku VGN, kuyang'anira Tricor kuyenera kuyimitsidwa. Mtundu wa creatinine chilolezo umalimbikitsidwa kuyang'aniridwa pafupipafupi m'miyezi itatu yoyambirira, komanso nthawi ndi nthawi mukamapangidwanso.

Mimba komanso kuyamwa

Zambiri pakugwiritsa ntchito mankhwalawa amayi apakati sikokwanira. Poyeserera kochitidwa pa nyama, palibe zotsatira za teratogenic zomwe zapezeka. Embryotoxicity adadziwika ndi ntchito fenofibrate panthawi ya mayeso mayeso a poizoni thupi la mkazi. Kugwiritsa ntchito Tricor pa nthawi ya pakati ndikotheka pokhapokha pofufuza kuchuluka kwa mapindu kwa mayi / chiopsezo kwa mwana wosabadwayo.

Zambiri pazimalumikizidwe a fenofibrate kapena metabolites ake mkaka wa m'mawere sikokwanira, chifukwa chake kugwiritsa ntchito mankhwalawa pa mkaka wa m`mawere kumatsutsana.

Kuyanjana kwa mankhwala

Tricor iyenera kuphatikizidwa mosamala ndi mankhwala ndi zinthu zotsatirazi:

anticoagulants pakamwa makonzedwe: fenofibrate kumawonjezera achire zotsatira za anticoagulants ndipo kuonjezera ngozi ya magazi (tikulimbikitsidwa kuchepetsa koyamba mlingo wa anticoagulants pafupifupi wachitatu ndipo kenako pang'onopang'ono kuonjezera izo),
cyclosporine: kwambiri aimpso kuwonongeka (kusintha) n`chotheka, motero, mwa odwala, ndikofunikira kuwunika momwe impso,
HMG-CoA reductase inhibitors (ma statins), mafupa ena: chiopsezo chowononga minofu yayikulu imawonjezeka,
thiazolidinedione derivatives (rosiglitazone, pioglitazone): kuchepa kwakumapeto kwa kuchepa kwa mafuta a cholesterol a HDL ndikotheka (ndikulimbikitsidwa kuti kuyang'anira cholesterol ya ndende ndikuyimitsa fenofibrate ndi kuchepa kwakukulu kwa chizindikiro ichi).

Zofanizira za Tricor ndi Lipantil 200 M, Lipofen SR, Eclip, Trilipix, Lopid, Fenofibrat Canon, etc.

Ndemanga za Traicore

Malinga ndi ndemanga, Tricor amatha bwino ntchito yayikulu - kutsitsa cholesterol ndi triglycerides. Pa mankhwala ndi mankhwalawa, odwala adazindikira matenda a shuga ndi LDL ndi HDL, amachepetsa ululu m'miyendo, kuwonda. Komabe, nthawi zambiri m'mawu awo, ogwiritsa ntchito amafotokoza mavuto obwera chifukwa cha kufooka kwa thupi, kupweteka kwam'mimba, kupsinjika, kufooka, kufooka, kupweteka kwa minofu, kusokoneza, ulesi, komanso kuchepa kwa kuthamanga kwa magazi. Chowonongeka china cha mankhwalawa, odwala amawona mtengo wake wokwera.