Dicinon: malangizo, ntchito, zikuonetsa
Dicinon ndi mankhwala osokoneza bongo, ndi amodzi mwa gulu la heentatic agents, omwe amayambitsa mapangidwe a thromboplastin. Zomwe zimagwira ndi Ethamsylate.
Mankhwala amathandizira kukulitsa mapangidwe akuluakulu a mucopolysaccharides omwe amateteza ulusi wa mapuloteni kuti asawonongeke m'makoma a capillaries. Kuphatikiza apo, zimathandizira kusintha kukhudzidwa kwa ma capillaries, kuwonjezera kukhazikika kwawo, komanso kusintha ma microcirculation.
Dicinon ndi he hentatic, antihemorrhagic ndi angioprotective chinthu, imasintha kukula kwa mtima la khoma, imapangitsa kukoka kwam'mimba.
Ilibe katundu wa hypercoagulant, samathandizira ku thrombosis, ilibe vasoconstrictor kwenikweni. Amabwezeretsa nthawi yosintha magazi. Sichikhudza magawo enieni a heentatic system.
Dicinon mothandizirana sizimakhudza kapangidwe ka magazi a zotumphukira, mapuloteni ake ndi lipoprotein. Pang'onopang'ono kumawonjezera zomwe zili za fibrinogen. Mlingo wa erythrocyte sedimentation ukhoza kuchepa pang'ono. Mankhwala limapangitsa kapena amachepetsa pathologically kuchuluka permeability ndi fragility ya capillaries.
Pambuyo pa utsogoleli wa iv, mankhwalawa amayamba kugwira ntchito pambuyo pa mphindi 5 mpaka 15, kuchuluka kwakukulu kumawonedwa pambuyo pa ola limodzi, kutalika kwa maola ndi maola 4-6.
Zizindikiro zogwiritsidwa ntchito
Kodi chimathandiza ndi chiyani Dicinon? Malinga ndi malangizo, mankhwalawa amalembedwa motere:
- Parenchymal (ndi kuwonongeka kwa ndulu, mapapu, impso, chiwindi) ndi capillary (ndi kuwonongeka kwa ziwiya zazing'onoting'ono) magazi,
- Kutulutsa kwachiwiri kumbuyo kwa thrombocytopathy (kutsika kwa maselo othandiza magazi kuundana) ndi thrombocytopenia (kuchepa kwa kuchuluka kwa mapulosi m'magazi),
- Hematuria (kukhalapo kwa magazi mkodzo), kuchepa magazi (kuchepa kwa magazi), kuchepa kwa magazi m'matumbo,
- Epistaxis pamasamba akuthamanga kwa magazi,
- Hemorrhagic vasculitis (ma microgrombosis angapo komanso kutupa kwa makoma a mavesvessels) ndi hemorrhagic diathesis (njira yamkati yowonjezera magazi kutulutsa magazi),
- Diabetesic microangiopathy (matenda a capillary a shuga mellitus).
Malangizo ntchito Dicinon, kuchuluka kwa mapiritsi ndi ma ampoules
Mlingo wa tsiku ndi tsiku wa mankhwalawa komanso nthawi yayitali ya chithandizo amatsimikiza ndi dokotala potengera kulemera kwa thupi komanso kuopsa kwa magazi.
Piritsi limamezedwa lonse, kutsukidwa ndi madzi oyera. Malinga ndi malangizo ogwiritsira ntchito Dicinon, muyeso umodzi wambiri ndi mapiritsi atatu. Mlingo weniweni umatsimikiziridwa ndi dokotala kutengera mitundu ya kutuluka magazi.
Pofuna kupewa kutuluka kwa magazi mu nthawi ya postoperative, akuluakulu amayikidwa mapiritsi 1-2 pambuyo maola 6 aliwonse, mpaka mkhalidwewo ukhazikika.
Kutuluka kwamkati ndi m'mapapo - mapiritsi 2 patsiku kwa masiku 5-10. Ngati pakufunika kuwonjezera njira ya chithandizo, mlingo umachepetsedwa.
Dicinon wa msambo - mapiritsi atatu kwa tsiku kwa masiku 10 - iyambike masiku 5 kusamba ndikutha pa tsiku 5 la msambo. Kuphatikiza zomwe zimachitika, mapiritsi amayenera kumwedwa molingana ndi chiwembu komanso magulu awiri azotsatira.
Ana anaikidwa tsiku lililonse mlingo wa 10-15 mg / kg mu 3-4 waukulu.
Odwala omwe ali ndi vuto la hepatic kapena aimpso ayenera kugwiritsidwa ntchito mosamala.
Dicinon jakisoni
Mlingo umodzi wa yankho la jakisoni nthawi zambiri umafanana ndi 0,5 kapena 1 ampoule, ngati kuli kotheka, ma 1.5 ampoules.
Zokhudza prophylactic musanachite opareshoni: 250-500 mg wa etamsylate ndi jekeseni wamkati kapena mu mnofu 1 ora musanachitidwe opareshoni
Neonatology - jakisoni wa mu mnofu wa Dicinon pa 10 mg / kg thupi (0.1 ml = 12.5 mg). Kuchiza kuyenera kuyambitsidwa mwa maola awiri atabadwa. Pakani mankhwalawa maola 6 aliwonse kwa masiku 4 kuti mupeze kuchuluka kwa thupi kwa 200 mg / kg.
Ngati mankhwalawa asakanizidwa ndi mchere, ndiye kuti uyenera kuperekedwa mwachangu.
Kugwiritsa ntchito pamutu
Dicinon imatha kupakidwa pamwamba (khungu kumezanitsa, kupopera mano) pogwiritsa ntchito nsalu yosalala yothira mankhwala.
Mwinanso kugwiritsa ntchito pakamwa pakamwa mankhwala ndi makulidwe a makolo.
Malangizo apadera
Musanayambe chithandizo, zifukwa zina zoyipa magazi ziyenera kutchulidwa.
Mankhwalawa sayenera kutumizidwa kwa odwala omwe ali ndi kubereka kwa glucose, kuperewera kwa lappase lactase (kuchepa kwa lactase mwa anthu ena a North) kapena glucose-galactose malabsorption.
Ngati njira yothetsera vutoli yaonekera kudzera m'mitsempha yolumikizira, siyingagwiritsidwe ntchito.
Zotsatira zoyipa
Malangizowa amachenjeza za mwayi wokhala ndi zotsatirapo zoyipa mukamapereka Dicinon:
- Kuchokera mbali ya chapakati mantha dongosolo ndi zotumphukira mantha dongosolo: mutu, chizungulire, paresthesia a m'munsi malekezero.
- Kuchokera kugaya chakudya: nseru, kutentha pa chifuwa, kulemera kwa epigastric dera.
- Zina: thupi siligwirizana, Hyperemia ya pakhungu la nkhope, kuchepa magazi systolic.
Contraindication
Dicinon amatsutsana milandu zotsatirazi:
- pachimake porphyria
- hemoblastosis mu ana (lymphoblastic ndi myeloid leukemia, osteosarcoma),
- thrombosis
- thromboembolism
- Hypersensitivity pamagulu a mankhwala ndi sodium sulfite,
- yoyamwitsa
- Hypersensitivity kuti sodium sulfite (yankho la iv ndi / m makonzedwe).
Kugwiritsa ntchito pa nthawi ya pakati ndikotheka pokhapokha pokhapokha ngati phindu la chithandizo cha mankhwala kwa mayi limayang'ana kuopseza kwa mwana wosabadwayo.
Bongo
Zambiri zosokoneza bongo sizinafotokozedwe mu malangizo. Maonekedwe kapena kukulitsa zovuta zake ndizotheka.
Analogs Ditsinon, mtengo pama pharmacies
Ngati ndi kotheka, Dicinon akhoza kuthandizidwa ndi analogue yogwira ntchito - awa ndi mankhwala:
Zofanana muzochita:
- Tranexam
- Aminocaproic acid
- Vikasol,
- Alfit-8.
Mukamasankha analogi, ndikofunikira kumvetsetsa kuti malangizo a Dicinon ogwiritsira ntchito, mtengo ndi kuwunika sikugwiranso ntchito ngati mankhwala omwe ali ndi vuto lofananalo. Ndikofunikira kupeza upangiri wa dokotala komanso kuti usasinthe popanda mankhwala.
Mtengo m'mafakitale aku Russia: Mapiritsi a Ditsinon 250 mg 100 ma PC. - kuchokera 377 mpaka 458 ma ruble, mtengo wa ma ampoules Dicinon yankho 125 mg / ml 2 ml 1 pc - kuchokera ma ruble 12, 100 ma PC. - kuchokera ma ruble 433, malinga ndi mafakitale 693.
Khalani otetezedwa ku kuwala ndi chinyezi, kuchokera kwa ana popanda kutentha osapitirira 25 ° C. Moyo wa alumali ndi zaka 5.
Zoyenera kufalitsa kuchokera ku mafakitala zimalembedwa ndi mankhwala.
Ndemanga 4 za "Dicinon"
Anandilowetsa ndi Dicinon atandichita opaleshoni. Ndikumvetsa kuti kuchepetsa mwayi wokhetsa magazi. Mankhwalawa anali kuloledwa nthawi zonse. Jakisoni alibe chowawa. Poyerekeza ndi zowawa zakumaso kwa msoko, sindinamve jakisoni konse.
Zaka zaposachedwa, ndakhala ndikuzunzidwa ndi ma CD ochulukirapo, makamaka tsiku lachiwiri ndi lachitatu, koma tsikuli linali lowopsa. Mankhwala amachita mwachangu. Zothandiza kwambiri! Ndipulumutseni. Sindikudziwa zomwe zikanachitika popanda iwo.
Ndili ndi nthawi yambiri ndipo ndimamwa Ditsinon masiku 5 zisanayambike kuti pasataye magazi ambiri.
Pamasiku otere, ndimatenga ascorutin, ikadzaza kwathunthu. Kutsika mtengo ndikutengera zomwezi ndi zofanana. Dicinon sanayese, ngakhale ndinamva zambiri zabwino za iwo.
Dicinon pa nthawi ya pakati - malangizo ogwiritsira ntchito
M'masiku oyamba oyembekezera, Dicinon amalembedwa popanda kuwopsa kwa mluza, m'mapiritsi okha komanso moyang'aniridwa ndi dokotala. Mu trimesters yachiwiri ndi yachitatu imagwiritsidwa ntchito:
- Kuthetsa magazi ochepa.
- Ndi kuzungulira kwa zinthu za placenta.
- Pothana ndi zotupa za m'mphuno.
Zisonyezero zogwiritsidwa ntchito pofikira
- Pofuna kupewa komanso kuyimitsa magazi a parenchymal ndi capillary magazi mu otolaryngology ndi opaleshoni,
- Mu opaleshoni yamaso a keratoplasty, kuchotsedwa kwa matenda a maso ndi khungu
- Ndili ndi mphuno kumbuyo kwa matenda oopsa,
- M'mano pakagwiritsidwe ntchito ka opaleshoni,
- Pochita opaleshoni yodzidzimutsa kuti muimitse magazi m'matumbo ndi m'mapapo, mu mitsempha - yokhala ndi stroke ischemic,
- Chizindikiro chake ndi hemorrhagic diathesis (kuphatikizapo matenda a Werlhof, matenda a Willebrand-Jurgens, thrombocytopathy),
- Matenda a shuga a shuga,
- Intracranial hemorrhage mu makanda obadwa kumene komanso makanda osabadwa.
Zomwe zimagwiritsidwa ntchito mu gynecology:
Dicinon woletsa kusamba ndi chida champhamvu komanso chothandiza, koma akuyenera kugwiritsidwa ntchito kuyimitsa nthawi yayitali ngati njira yomaliza, ndipo atangoyang'ana ndi dokotala ndikuwonetsa zofunikira zololeza.
Nthawi zina, Dicinon amayenera kutengedwa ndi magazi omwe amayamba chifukwa chogwiritsa ntchito njira za kulera - zapakati pa mtima. Pambuyo pochotsa mlengalenga pogwiritsa ntchito Dicinon, magazi amasiya.
Momwe mungagwiritsire ntchito Dicinon, mlingo
Mapiritsi a akulu:
Mlingo wofanana watsiku ndi tsiku wa Dicinon ndi 10-20 mg / kg kulemera kwa thupi, wogawidwa mu 3-4 Mlingo. Nthawi zambiri, mlingo umodzi ndi 250-500 mg 3-4 nthawi / tsiku.
Mwapadera, mlingo umodzi ungathe kuwonjezeka mpaka 750 mg 3-4 nthawi / tsiku.
Dicinone wokhala ndi nthawi yolemetsa amadwala mapiritsi awiri a 250 mg katatu patsiku pakudya. Mankhwalawa amatha mpaka masiku 10, kuyambira masiku asanu isanayambike magazi.
Mu nthawi yogwira ntchito, mankhwalawa amawonetsedwa mu mlingo umodzi wa 250-500 mg maola 6 aliwonse mpaka chiwopsezo chakutuluka magazi chikazimiririka.
Hemorrhagic syndrome: katatu patsiku, 6-8 mg / kg, nthawi yayitali mpaka masabata awiri, malinga ndi zomwe zimachitika, maphunzirowa akhoza kubwerezedwa mu sabata limodzi.
Matenda amkati: Malangizo ambiri otenga mapiritsi 2 a Dicinon 250 mg 2 mpaka 3 pa tsiku (1000-1500 mg) ndi zakudya, ndi madzi oyera pang'ono.
Zingati kumwa Dicinon? Kutalika kwa nthawi komanso nthawi yayitali kumwa mapiritsi kuyenera kutumizidwa ndi dokotala, chithandizo chokwanira chimakhala mpaka masiku 10.
Mapiritsi a ana (opitilira zaka 6):
Mlingo wa tsiku ndi tsiku wa Dicinon wa ana ndi 10-15 mg / kg mu Mlingo wa 3-4. Kutalika kwa ntchito kumadalira zovuta za kutaya magazi ndipo kuyambira masiku atatu mpaka 14 kuchokera pomwe magazi amatuluka. Mapiritsi ayenera kumwedwa nthawi yakudya kapena itatha.
Palibe maphunziro pa kugwiritsa ntchito mapiritsi a Dicinon mwa odwala omwe ali ndi vuto la chiwindi kapena impso. M'magulu odwala, gwiritsani ntchito mankhwalawa mosamala.
Malangizo a Dicinon ogwiritsa ntchito - jakisoni wa akulu
Mlingo woyenera tsiku ndi tsiku ndi 10-20 mg / kg, wogawidwa pakati pa 3-4 v / m kapena iv (wosakwiya).
Diabetesic microangiopathy (hemorrhage): jakisoni wamitsempha wa 0,25 magalamu katatu patsiku, jakisoni wa miyezi itatu.
Pochita opaleshoni, amapangidwanso prophylactically ndi IV kapena IM 250-500 mg 1 ola limodzi asanachitidwe opareshoni. Nthawi ya opareshoni, I / O imayendetsedwa ndi 250-500 mg. Opaleshoniyo ikamalizidwa, 250-500 mg ya Dicinon imayendetsedwa maola 6 aliwonse mpaka ngozi yotaya magazi ithera.
Ditsinon - jakisoni wa ana
Mlingo watsiku ndi tsiku ndi 10-15 mg / kg kulemera kwa thupi, logawidwa majekiseni atatu.
Mu neontology: Dicinon amaperekedwa mu / m kapena mu / mu (pang'onopang'ono) pa mlingo wa 12.5 mg / kg (0.1 ml = 12.5 mg). Kuchiza kuyenera kuyamba mkati mwamaola awiri atabadwa.
Contraindication
Kugwiritsa ntchito mapiritsi ndi jakisoni wa Dicinon komwe kumatsutsana:
- Hypersensitivity kwa yogwira mankhwala kapena magawo a mankhwala,
- thrombosis ndi thromboembolism,
- pachimake porphyria.
Gwiritsani ntchito mosamala ngati magazi akutuluka pa maziko a mankhwala osokoneza bongo.
Zotsatira zoyipa Dicinon
- mutu
- chizungulire
- Kuyamba ndi redness pakhungu,
- nseru
- paresthesia a miyendo.
Zomwe amachita ku Dicinon ndizosakhalitsa komanso zofatsa.
Pali umboni kuti ana omwe ali ndi pachimake lymphoid ndi myelo native leukemia, osteosarcoma, etamsylate, amagwiritsidwa ntchito kupewa magazi, amayambitsa leukopenia.
Pambuyo pa jakisoni, redness ndi kuyabwa zitha kuwoneka pamalo operekera jakisoni, edema ya Quincke sichiwoneka kawirikawiri, mphumu ya bronchial imayamba kukulira. Nthawi zina munthu akhoza kukhala ndi anaphylactic.
Analogs Dicinon, mndandanda
Analogs Dicinon pa mfundo yake:
- Etamsylate
- Mononine
- Octanine F
- Octane
- Protamine sulfate
- Sintha
Chonde dziwani - malangizo ogwiritsira ntchito Zakudya, mtengo ndi kuwunika kwa analogues sizoyenera. Mulimonsemo, sizingagwiritsidwe ntchito ngati chiwongolero chakugwiritsa ntchito ndi Mlingo wa analogues! Pakufufuza zomwe zingalowe m'malo mwa Zakudya, kuyankhulana ndi dokotala woyenera ndikofunikira.