Njira Yowunikira Yopangira Shuga Yopanga

Chipangizochi, chopangidwira anthu omwe ali ndi matenda ashuga komanso omwe amafunikira jakisoni tsiku ndi tsiku, ayenera kugulitsa chilimwechi ndipo azidzagulitsa ndikulembetsa pamtengo wa $ 50 pamwezi.

Chomwe chimasiyanitsa ndi kuthekera kolosera kuchuluka kapena shuga pang'ono pasadakhale komanso kutumiza mauthenga ochenjeza kwa ogwiritsa kutengera izi.

Dongosolo limakhala ndi sensor ya sensor ya Guardian Sensor 3 ndi chotumizira chaching'ono chomwe chimatumiza kudzera mu data ya Bluetooth yomwe imasonkhanitsidwa mumayendedwe opitilira gawo la shuga la wogwiritsa ntchito mofananamo pa foni yamakono ya wosuta. Pogwiritsa ntchito luso la IBM Watson waluso wamaluso, Guardian Connect ikhoza kuwachenjeza ogwiritsa ntchito kuopsa kwa hyper- kapena hypoglycemia mphindi 60 phwando lisanachitike. Chenjezo ili likhoza kulandiridwa osati ndi wogwiritsa ntchito, komanso ndi abale ake, omwe amathanso kutsata deta yowunika shuga.

Dongosolo lanyenyezi lino, pogwiritsira ntchito mayankho otsekedwa, tayesedwa bwino ndipo lawonetsa kulosera kolondola kwa zochitika za hypoglycemic za 98,5%. Masiku ano, Guardian Connect ndiye koyamba komanso kokhako kodziyang'anira pokha popanga shuga, komwe kumagwiritsa ntchito machenjezo.

Pamodzi ndi chida chachipatala, wogwiritsa ntchitoyo amapeza yekha mlangizi wa shuga.IQ "wanzeru", yemwe amapangidwa kuti azithandiza odwala matenda ashuga tsiku lililonse polimbana ndi matendawa.

Mlangizi wa IBM Watson yemwe amachokera pamasom'pamaso amasanthula momwe shuga ya munthu wogwiritsa ntchito imagwirizira chakudya chake, mulingo wa insulin, zochitika zatsiku ndi tsiku, ndi zina.

Kusintha Koyamba

Mu 1869, ku Berlin, wophunzira wazaka 22 wazachipatala Paul Langerhans, akuwerenga ndi makina oonera kapangidwe kake kapangidwe kake, adawonetsa maselo omwe sanali odziwika omwe amapanga magulu omwe adagawidwanso molondola gland. Cholinga cha "timitsempha tating'onoting'ono tomwe timapanga maselo", omwe amadzadziwika kuti "zilumba za Langerhans," sichinadziwike, koma pambuyo pake Eduard Lagus adawonetsa kuti chinsinsi chimapangidwa mwa iwo chomwe chimathandizira pakugaya.

Mu 1889, katswiri wazamakhalidwe wa ku Germany a Oscar Minkowski, pofuna kuwonetsa kuti kapamba amawaganiziranso kugaya, adayambitsa kuyesa komwe nduluyo idachotsedwa mu galu wathanzi. Patatha masiku ochepa chiyambireni kuyesera, wothandizira Minkowski, yemwe anali kuyang'anira zinyama zantchire, adayang'ana chidwi cha ntchentche zambiri zomwe zimalowa mkodzo wa galu woyeserera. Atasanthula mkodzo, adapeza kuti galuyo adathira shuga mkodzo. Uwu udali mawonekedwe oyamba omwe amatilola kulumikiza ntchito ya kapamba ndi matenda ashuga.

Ntchito ya Sobolev Sinthani

Mu 1900, a Leonid Vasilievich Sobolev (1876-1919) atayesa anapeza kuti atanyamula zitsamba zakunyumba, touthies wam'mimba ndi zisumbu za Langerhans zimasungidwa. Kuyesaku kunachitika mu labotale ya Ivan Petrovich Pavlov. Popeza zochitika za ma islet cell zimapitilira, matenda a shuga samachitika. Zotsatira izi, komanso chidziwitso chodziwika bwino cha kusintha kwa ma islet kwa odwala omwe ali ndi matenda ashuga, adalola Sobolev kunena kuti zisumbu za Langerhans ndizofunikira pakuwongolera kagayidwe kazachilengedwe. Kuphatikiza apo, Sobolev adalimbikitsa kugwiritsa ntchito gland ya nyama zatsopano, momwe ma bisalomo amapangidwira bwino pokhudzana ndi zida zogaya, kupatula chinthu ndi zotsutsana ndi matenda. Njira zopatula mphamvu ya mahomoni yogwiritsidwa ntchito pancreas, yomwe ikufunsidwa ndikufalitsidwa ndi Sobolev, idagwiritsidwa ntchito mu 1921 ndi Bunting ndi Best ku Canada popanda kutanthauza Sobolev.

Kuyesa kudzipatula pa mankhwala antidiabetes

Mu 1901, njira yofunika yotsatirayi idatengedwa: Eugene Opie adawonetsa kuti "Matendawa matenda a shuga ... amayamba chifukwa cha kuwonongeka kwa ziphuphu zakumaso, ndipo zimachitika pokhapokha matupi awonongedwa pang'ono kapena atawonongeka kwathunthu.". Ubwenzi wapakati pa matenda ashuga ndi kapamba unkadziwika kale, koma mpaka pamenepo sizinadziwike kuti shuga imalumikizidwa ndi ma islets.

Kwa zaka makumi awiri zotsatira, kuyesayesa kambirimbiri kunachitika kuti kudzipatula kokhako ngati njira yakuchiritsira. Mu 1906 de Zweltzer adachita bwino pakuchepetsa kuchuluka kwa shuga m'magulu oyesera ndi zotulutsa za pancreatic, koma sanathe kupitiliza ntchito yake. Scott (E. L. Scott) Pakati pa 1911 ndi 1912 adagwiritsa ntchito kachigawo kena kanyumba ku University of Chicago ndikuwona "kuchepa pang'ono kwa glucosuria," koma sanathe kutsimikizira oyang'anira ake za kufunikira kwake, ndipo posakhalitsa kuyesaku kuyimitsidwa. Israel Kleiner en adawonetsa zomwezi ku Rockefeller University mu 1919, koma ntchito yake idasokonezedwa ndi kufalikira kwa Nkhondo Yoyamba Yapadziko Lonse, ndipo sakanatha kuimaliza. Ntchito yofananira itatha kuyesa ku France mu 1921 idasindikizidwa ndi pulofesa wothandizira pa physology ku Bucharest School of Medicine ndi Pharmacology Nicolae Paulesco, ndipo ku Romania amamuyesa wofalitsa insulin.

Kubera ndi Best insulin katulutsidwe Sinthani

Komabe, kutulutsidwa kwenikweni kwa insulin ndi kwa gulu la asayansi ku Yunivesite ya Toronto. Frederick Bunting amadziwa za ntchito ya Sobolev komanso Ndinazindikira malingaliro a Sobolev, koma sanatchulidwe kwa iwo. Kuchokera pamawu ake: “Mangani chimbudzi kwa galu.Siyani galuyo mpaka ziphuphu ziwonongeka ndikangotsala timabowo tokha. Yesani kuwunikira chinsinsi chamkati ndikuchita pa glycosuria ... "

Ku Toronto, Bunting adakumana ndi a J. MacLeod ndikumufotokozera malingaliro ake kuti ali ndi chiyembekezo chofuna kumuthandiza ndi kupeza zida zomwe angafunikire kuti azigwira. Lingaliro la Kudzimva poyamba limamveka kwa pulofesayo ndilopusa komanso loseketsa. Koma wasayansi wachichepere adakwanitsa kutsimikiza Macleod kuti athandizire ntchitoyi. Ndipo nthawi yachilimwe cha 1921, adapereka bunting ndi labotale yaku yunivesite ndi wothandizira, a Charles Best wazaka 22, adamupatsanso agalu 10. Njira yawo inali yoti phula lam'mimba limangirizidwa kuzungulira pancreas, kuletsa kubisala kwa madzi a pancreatic ku gland, ndipo milungu ingapo pambuyo pake, maselo otuluka akamwalira, masauzande a zilumba adatsala amoyo, pomwe adatha kudzipatula mapuloteni omwe adachepetsa kwambiri shuga m'mwazi wa agalu okhala ndi kapamba wochotsedwa. Poyamba ankatchedwa "ayletin."

Pobwerera ku Europe, MacLeod adazindikira kufunika kwa ntchito yonse yomwe anthu omwe adawagwiritsa ntchito amakhala nayo, komabe, kuti athe kutsimikiza ndi mtima wonse njira imeneyi, pulofesayo adafuna kuti ayesenso pamaso pake. Ndipo milungu ingapo pambuyo pake zinaonekeratu kuti kuyesa kwachiwirinso kunachita bwino. Komabe, kudzipatula ndi kuyeretsa kwa "ayletin" kuchokera ku zikondamoyo za agalu kunali ntchito yotenga nthawi yayitali komanso yayitali. Kubuwa anaganiza zoyesa kugwiritsa ntchito kapamba wa chipatso cha mwana wa ng'ombe, komwe ma enzymes opangira zakudya sanapangidwebe, koma insulin yokwanira idapangidwa kale. Izi zidathandizira kwambiri ntchitoyi. Pambuyo pothana ndi vutoli kuchokera komwe kunachokera insulini, ntchito yotsatira inali kuyeretsa mapuloteni. Kuti athane ndi vutoli, mu Disembala 1921, Macleod adabweretsa wanzeru wanzeru, James Collip (waku Russia). amene pomaliza pake adakwanitsa kupanga njira yothandiza kuyeretsa insulin.

Ndipo pa Januware 11, 1922, pambuyo poyesa ambiri ndi agalu, matenda ashuga, Leonard Thompson wazaka 14 adalandira jakisoni woyamba wa insulin. Komabe, zomwe zinakumana ndi insulin sizinaphule kanthu. Tingati sanayeretsedwe mokwanira, ndipo izi zidapangitsa kuti ziwonetsero zikuluzikulu, choncho, jakisoni wa insulin adayimitsidwa. Kwa masiku 12 otsatira, Collip adagwira ntchito molimbika mu labotale kuti athandizire kuchotsa. Ndipo pa Januware 23, Leonard adalandira mlingo wachiwiri wa insulin. Nthawi iyi kupambana kwathu kunali kwathunthu, sikuti panali zotsatira zoyipa zodziwikiratu, koma wodwalayo adasiya kupititsa patsogolo shuga. Komabe, pambuyo pake Bunting ndi Best sanagwire ntchito limodzi ndi Collip ndipo posakhalitsa adagawana naye.

Kuchuluka kwa insulin yoyenera kunafunikira. Ndipo njira yothandiza isanapezeke yopanga insulin, ntchito yambiri idachitika. Udindo wofunikira mu izi udasewera ndi kudziwika kwa Bunting ndi Eli Lilly. , mwini wa kampani imodzi yopanga zamankhwala padziko lonse Eli Lilly ndi Company. gwero silinatchulidwe tsiku la 2661

Chifukwa cha kusinthaku, Macleod ndi Bunting mu 1923 adalandira Mphotho Nobel mu physiology kapena mankhwala. Poyamba, a Bunting anakwiya kwambiri kuti womuthandiza Best sanapatsidwe nawo mphothoyo, ndipo poyamba anakana ndalamazo, koma kenako anavomera kulandira pempholo, ndipo mokwiya anagawana gawo lake ndi Best gwero silinatchulidwe masiku 3066 . MacLeod adachitanso chimodzimodzi, akugawana mphotho yake ndi Collip gwero silinatchulidwe masiku 3066 . Patent ya insulini idagulitsidwa ku University of Toronto ndi dollar limodzi. Kupanga kwa malonda a insulin pansi pa dzina loti Iletin kunayambika mu 1923 ndi kampani yopanga mankhwala Eli Lilly ndi Company.

Kapangidwe ka Kukongoletsa Kapangidwe

Mbiri yodziwitsa ndendende kuchuluka kwa ma amino acid omwe amapanga mamolekyu a insulin (zomwe zimatchedwa pulayimale) ndi ya wasayansi wopanga maselo a ku Britain a Frederick Senger. Insulin inali mapuloteni oyamba omwe kapangidwe kake kanatsimikiziratu mu 1954. Chifukwa cha ntchito yomwe idachitika mu 1958, adalandira mphotho ya Nobel mu Chemistry. Ndipo patatha zaka pafupifupi 40, a Dorothy Crowfoot-Hodgkin pogwiritsa ntchito njira ya X-ray adatsimikiza mawonekedwe a molekyulu ya insulin. Ntchito yake imapatsidwanso mphoto ya Nobel.

Sinthani Sinthani

Kupanga koyamba kwa insulin koyambirira kwa zaka za 1960 kunachitika nthawi yomweyo ndi Panagiotis Katsoyanis ku University of Pittsburgh ndi Helmut Zahn ku RFTI Aachen. Insulin yoyamba yopangidwa ndi chibadwa cha anthu idapezeka mu 1978 ndi Arthur Riggs ndi Keiichi Takura ku Beckman Research Institute ndikutenga nawo gawo kwa Herbert Boyer kuchokera ku Genentech pogwiritsa ntchito ukadaulo wa DNA (rDNA), adapangitsanso kukonzekera koyamba kwa insulin - Beckman Research Institute mu 1980 ndi Genentech mu 1982 (pansi pa dzina la Humulin). Insulin yomwe ikubwezeretsanso imapangidwa ndi yisiti yophika mkate ndi E. coli.

Njira zopangira masinthidwe amtundu wa nkhumba ndi nyama zina kukhala anthu, insulini, koma ukadaulo wazinthu zakutsogolo umapatsa zambiri ndipo ukutsogolera kale, chifukwa yopanga zambiri komanso yothandiza.

Chofunikira kwambiri pakuphatikizika ndi kutulutsa kwa insulin ndikuwonjezera kuchuluka kwa shuga m'magazi.

Smart insulin ndi yachangu kuposa mankhwala amakono

Ndi mitundu yonse iwiri ya matenda ashuga, thupi limalephera kuwongolera shuga. Mtundu woyamba wa matenda ashuga, izi zimachitika chifukwa chakuti ma cell omwe amapanga insulini amawonongeka. Popanda insulini, thupi limabowola chinthu chachikulu cha "kupomera" glucose m'maselo, momwe angagwiritsidwe ntchito mphamvu. Anthu omwe ali ndi matenda a shuga 1 amadalira kwathunthu insulin.

Zowonadi zochepa zokhudza matenda ashuga:

Mu 2012, anthu 29 miliyoni miliyoni ku United States adwala matenda ashuga, ndipo chiwerengero cha anthu 9,3% mdzikoli
Pafupifupi 5% ya shuga amayamba chifukwa cha matenda a shuga omwe amadalira insulin, kapena matenda a shuga 1
Mu 2012, ndalama zonse zokhudzana ndi matenda a shuga ku United States zidaposa $ 245 biliyoni.

Ngati wodwala matenda amtundu wa 1 sangayendetse matenda ake moyenera, izi zimabweretsa zotsatira zoyipa. Hyperglycemia, ndiye kuti, shuga okwera mtima, amalimbikitsa ngozi ya matenda amtima, kuwonongeka kwa maso ndi mitsempha, ndi zovuta zina. Hypoglycemia, kapena shuga yochepa ya magazi, imatha kubweretsa kukomoka, ngakhale kufa kwa wodwala.

Ofufuzawo akuti insulin yawo yanzeru Ins-PBA-F imatha kuyankha mwachangu komanso moyenera pakasinthidwe ka shuga m'magazi poyerekeza ndi insulin analogue (LEVIMIR) yomwe imagwira ntchito kwa nthawi yayitali. Ntchito yawo idawonetsa kuti kuchuluka kwa matenda a shuga mu mbewa zokhala ndi matenda ashuga ku Ins-PBA-F ndi chimodzimodzi ngati nyama zathanzi zomwe zimatulutsa insulini yakeyawo.

Pulofesa Chow akuti: "Uku ndikofunika kwambiri pakupangira mankhwala a insulin. Insulin yathu imayendetsa bwino kwambiri shuga kuposa njira zonse zothandizira odwala masiku ano. ”

Kwazaka makumi angapo zapitazi, chithandizo cha matenda ashuga asintha kwambiri. Masiku ano, mapampu a insulini ochenjera amagwiritsidwa ntchito, mitundu inayi ya insulini yawonekera, ndi zina zambiri. Koma odwala amafunikirabe kudziyimira payokha mosamala pazotsatira zake. Kuchuluka kwa insulini yoyenera kuperekedwa kumatha kusintha mosiyanasiyana. Zimatengera kuchuluka ndi chakudya chomwe amadya, kuchuluka kwa zochitika zolimbitsa thupi, ndi zina zambiri.

Insulingent Insulin Ins-PBA-F imangopangidwira pokhapokha ngati ikufunika. Izi zimathandizira kuyang'anira matenda ndikuchotsa chiwopsezo cha dosing yolakwika.

Smart Insulin Ins-PBA-F - Yoyamba yamtundu wake

Smart insulin sindiyo yokha yomwe imapanga insulin, koma ndi yoyamba pakati pazofanizira zake zomwe sizikufunika kupangidwa ndi zida zapadera zoteteza kapena zotchingira mapuloteni zoletsa insulin pamene shuga ndi ochepa. Zogulitsa zotere zimalumikizidwa ndi chiwopsezo chowonjezereka cha zotsatira zoyipa zosafunikira, kuphatikizapo kuyankha kwamthupi.

Ins-PBA-F ili ndi mchira wopangidwa ndi phenylboronic acid (PBA), womwe, pamlingo wamba wa shuga, umamangiriza tsamba lantchito ya insulin ndikuletsa ntchito yake. Koma kuchuluka kwa shuga kukakwera, glucose amamangiriza ku phenylboronic acid, chifukwa chomwe tsamba lotseguka la mahomoni limamasulidwa, ndikuyamba kuchita.

Pulofesa Chow adati: "Ins-PBA-F yathu ikukwaniritsidwa ndi tanthauzo la" insulin yoyenera, "chifukwa molekyuyo imayankha shuga. Ili ndiye loyamba lake. ”

Ndalama zopangira insulin yanzeru zimaperekedwa ndi U.S. National Institutes of Health, Juvenile Diabetes Foundation, Harry Helmsi Charity Foundation, ndi Tayebati Family Foundation.

Kodi kusamala kwa mahomoni ndi chiyani?

Uku ndiye kuchuluka kwa mahomoni omwe mutha kuwongolera kagayidwe kazakudya mthupi. Ngati dokotala amadziwa mphamvu yanu ya mahomoni, zimamuthandiza kudziwa ndendende momwe mafuta ofikira amadzisonkhanira kwambiri, ndi ochepa.

Pamene mulingo wa estradiol, komanso testosterone ndi mahomoni a chithokomiro T3 (mu mawonekedwe ake omasuka) abwezeretsedwa m'thupi, izi zimapangitsa kuti insulin chitetezo chitha.

Ngati tanthauzo la matendawa ndi losavuta, ndiye kuti ndi njira yomwe, chifukwa chakuchita bwino kwa kapamba, kapena pamene ma receptor

kagayidwe kachakudya mu thupi zimasokonekera. Izi zimadzetsa kuwonjezeka kwa shuga wamagazi ndikuphwanya kapangidwe kake ka lipid.

Pankhaniyi, shuga m'magazi amayenera kupezeka pafupipafupi - popanda iwo, nthawi ya ubongo imawerengeredwa m'mphindi. Chifukwa shuga m'magazi ndikofunikira.

Komabe, kuchuluka kwake kwotalikirapo kungayambitsenso zisokonezo zomwe zingachitike patapita zaka ndikuwadzetsa zosintha zina.

Kodi chifukwa chiyani shuga wambiri ndi woopsa?

Mwazi wa magazi uyenera kukhala m'magulu 3.3 - 6.6 mmol / L. Pakakhala kuchepa kwa shuga m'magazi, ubongo wathu umakana kugwira ntchito - zomwe zimayambitsa kugona, kusowa chikumbumtima ndipo, nthawi zina, kumayambitsa kutseka kwa hypoglycemic.

Ndi kuchuluka kwa shuga m'magazi, chomaliza chimakhala ndi poizoni. Miyezo yokwezeka ya glucose imapangitsa kuti makoma amitsempha yamagazi ayambe kunenepa komanso amachepa.

Kuphwanya khoma la mtima kumabweretsa chisokonezo chonse cha kupuma kwa minofu. Chowonadi ndi chakuti kudzera mu khoma lokwinya la zotengera, njira za metabolic ndizovuta kwambiri.

Chifukwa chake, mpweya ndi michere zimasungunuka m'mwazi ndipo siziperekedwa kwa wolandirayo - ziwalo zathupi, ndipo ndizosakwanira.

Mitundu ya matenda ashuga

M'malo mwake, lingaliro la matenda a shuga limaphatikiza matenda angapo wamba, omwe kuphwanya kwa insulin ndi kusintha komwe kumayenderana ndi kagayidwe kachakudya ka thupi. Pakadali pano, ndichizolowezi kupatula mtundu wa 1 ndi matenda ashuga a 2 - kupatukana uku ndi koyenera, chifukwa kudziwa mtundu wa matenda ashuga kumakupatsani mwayi wopereka chithandizo choyenera.

Musanaganizire za mitundu ya shuga, ndikofunikira kumvetsetsa momwe thupi limagwirira ntchito komanso momwe thupi limagwirira ntchito.

Kodi udindo wa kapamba ndi chiyani?

Chifukwa chake, kuli madera ena kapamba wotchedwa islets (insulin), magawo a zikondwererozi amakhala ndi maselo a beta omwe amapanga insulin. Maselo a Beta pawokha amayang'aniridwa bwino ndi ma receptors apadera a misempha yamagazi.

Ndi kuchuluka kwa glucose, amagwira ntchito modabwitsa ndipo amatulutsa insulin yambiri m'magazi. Ndi mulingo wama glucose osiyanasiyana 3.3-6.6 mmol / L, maselo amenewa amagwira ntchito mumalowedwe akuluakulu - kusunga oyambira a insulin.

Kodi insulin ndi chiyani?

Mungamvetse bwanji kuti munthu amayamba kudwala matenda ashuga?

Ndikofunikira kuyeza kuchuluka kwa glucose ndi insulin 2 mawola atatha kudya - iyi ndiyo njira yabwino yodziwira zomwe zimapangitsa thupi kukhala ndi matenda ashuga.

Ngati glucose m'thupi amachokera ku mayunitsi 140 mpaka 200 (ola limodzi mutatha kudya) - chiopsezo chotenga matenda a shuga ndichokwera kwambiri. Gawo lake loyamba ndikotheka.

Ngati kuchuluka kwa glucose mutatha kudya ndikuchokera ku mayunitsi 140 mpaka 200 (koma osaposa) - ichi ndi matenda a shuga.

Muyenera kulumikizana ndi endocrinologist kuti mumupime.

Dziwani kuti ma laboratori osiyanasiyana akhoza kukhala ndi mitengo yosiyanasiyana yothetsera shuga ndi insulin. Chifukwa chake, onanani ndi dokotala kuti ndi gawo liti lomwe muyenera kuyamba kuda nkhawa ndikuyamba kulandira chithandizo.

Kodi chiwopsezo cha mkazi yemwe ali ndi shuga wambiri ndi chiyani?

Dziwani kuti izi ndizofunikira: malinga ndi kafukufuku wa zamankhwala, ngakhale kuchulukitsa pang'ono kwa shuga m'magazi kungakhale pachiwopsezo cha matenda a shuga.

Ngati shuga othamanga akukwera ndi magulu opitilira 126, ndipo shuga wokhazikika amatha magawo 200 kapena kupitilira, akhoza kukhala akupha.

Kukula kwa matenda ashuga kumatha kuwonetsedwa ndi glucose 2 maola atatha kudya oposa 200 mg / dl.

Zizindikiro ndi matenda a shuga

Tiyenera kudziwa kuti nthawi zambiri, chithunzi chowoneka bwino cha matenda ashuga pakati pa odwala ambiri sichimawonedwa. Kwenikweni, pali zizindikiro zosakhazikika zomwe sizimakakamiza wodwalayo kukaonana ndi dokotala munthawi yake.

• ludzu losalekeza

• Kukodza pafupipafupi popanda matenda a impso kapena kwamkodzo

• Nthawi yayifupi kapena yayitali yochepetsera maonedwe owoneka

khungu ndi mucous nembanemba

Komabe, pazizindikiro izi zokha sizingatheke kuzindikira matenda ashuga, kuyesa kwa labotale ndikofunikira.

Zizindikiro Zakuchipa cha Matenda A shuga

Kuzindikira koyambirira kumakhazikitsidwa pa mayeso awiri: kudziwa kusala kwamwazi wamagazi ndikuzindikira shuga ya mkodzo.

Kuyesedwa kwa magazi kwa glucose ndiye chizolowezi ndi matenda. Nthawi zambiri, kuchuluka kwa shuga m'magazi kumatha kusiyanasiyana pakati pa 3.3 - 6.6 mmol / L.

Mukatha kudya, kuchuluka kwa shuga kumatha kuwonjezeka kwakanthawi, koma kusintha kwake kumachitika mkati mwa maola 2 mutatha kudya. Chifukwa chake, kupezeka kwa shuga m'magazi kuposa 6,6 mmol / l kungasonyeze vuto la shuga kapena labotale - sipangakhale zosankha zina.

Kuyesa kwa mkodzo kwa glucose ndi njira yodalirika yodziwira matenda ogwiritsira ntchito matenda a shuga. Komabe, kusapezeka kwa shuga mumkodzo sikungakhale chizindikiro chakuti matendawa alibe.

Nthawi yomweyo, kukhalapo kwa shuga mkodzo kumawonetsa njira yoopsa ya matendawa yokhala ndi shuga m'magazi osachepera 8.8 mmol / L. Chowonadi ndi chakuti impso, zikasefa magazi, zimatha kubwezeretsa glucose kuchokera mkodzo woyamba kubwerera kumagazi.

Komabe, ngati kuchuluka kwa shuga m'magazi kukupitilira mfundo zina (aimpso), glucose pang'ono amakhala mkodzo. Ndi izi: Zizindikiro zambiri za matenda ashuga zimakhudzana - kuchuluka kwa ludzu, kukodza pokoka, khungu lowuma, kuchepa kwambiri pamenepa chifukwa chakusowa kwamadzi.

Chowonadi ndi chakuti shuga amasungunuka mu mkodzo, chifukwa cha kupanikizika kwa osmotic, amakoka madzi limodzi ndi izo, zomwe zimatsogolera kuzizindikiro zomwe tafotokozazi. .

Kodi mungadziwe bwanji kuti shuga alibe bwino?

Muyenera kuyeza kuchuluka kwake munthawi yomwe simunadye chakudya cham'mawa. Chakudya chomaliza, osachepera maola 12 ayenera kudutsa. Ngati kuchuluka kwa glucose kumachokera ku 65 mpaka 100 mayunitsi, ichi ndi chizindikiro chokhazikika.

Madokotala ena akuti kuwonjezeka kwa mayunitsi ena 15 - mpaka kufika kwa mayunitsi 115 - ndichinthu chovomerezeka.

Ponena za kafukufuku waposachedwa, asayansi amati kuwonjezeka kwama glucose oposa 100 mg / dl ndi chizindikiro choopsa.

Izi zikutanthauza kuti gawo loyamba la matenda ashuga limatha kukula mthupi. Madotolo amatcha glucose osagwirizana ndi thupi.

Izi ndizovuta kwambiri kuposa kudziwa kuchuluka kwa shuga, chifukwa ma insulin amatha kusiyanasiyana. Tikudziwitsani insulin.

Kuwunikira kwa kuchuluka kwa insulin komwe kumachitika pamimba yopanda kanthu ndi magawo 6-25. Mlingo wa insulin 2 maola mukatha kudya umafika magawo 6-35.

Nthawi zina, kuzindikiridwa kwa shuga okwera kapena kupezeka kwa shuga mkodzo sikupereka umboni wokwanira kwa dokotala kuti adziwe ndikupereka chithandizo chokwanira. Kuti muwone bwino zonse zomwe zimachitika mthupi la wodwalayo, maphunziro owonjezera amafunikira.

Mayeso awa athandizira kudziwa kutalika kwa kuchuluka kwa shuga m'magazi, kuchuluka kwa insulin komwe kumakhala kuphwanya kagayidwe kazakudya, kudziwa nthawi ya kupangika kwa acetone ndikuchita panthawi yake pochiza vutoli.

• kuyesa kwa glucose

• Kudziwitsa kuchuluka kwa insulin

• Kudziwitsa za kuchuluka kwa acetone mu mkodzo

• Kudziwitsa glycosylated magazi hemoglobin

• Kudziwitsa kuchuluka kwa magazi a fructosamine

Mayeso a kulolera a glucose

Zimapangidwa kuti ziwulule momwe kapamba amagwirira ntchito pansi, zomwe amasunga. Kufufuza kumeneku kumakuthandizani kuti mumvetse bwino mtundu wa matenda osokoneza bongo, kuzindikira mitundu yobisika ya matenda osokoneza bongo (kapena otchedwa prediabetes) ndipo amathandizira kutsimikizira njira yabwino kwambiri yothandizira odwala matenda ashuga.

Kukonzekera mayeso kumafunikira kulumikizana ndi ofesi ya zamankhwala m'mawa wopanda kanthu (chakudya chotsiriza chiyenera kukhala osachepera maola 10 kusanachitike mayeso). Kugwiritsa ntchito mankhwala omwe amakhudza shuga m'magazi kuyenera kuyimitsidwa pasadakhale.

Boma la ntchito ndi kupuma, zakudya, kugona ndi kudzuka ziyenera kukhalabe zomwezo. Patsiku la mayeso, ndizoletsedwa kudya zakudya, zakumwa zomwe zimakhala ndi shuga komanso mankhwala ena aliwonse okhala ndi organic.

Mutha kukhala ndi kadzutsa kumapeto kwa mayeso.

1. Kusintha kwa magazi kuti mupeze kuchuluka kwa glucose musanatsike shuga. Ngati magazi a glucose aposa 6.7 mmol / L, kuyesaku sikuchitika - sizofunikira. Pankhaniyi, kuphwanya njira za metabolic ndikudziwikiratu.

2. Wodwalayo amapemphedwa kuti amwe kapu yamadzimadzi (300 ml) yamadzimadzi ndi 75gr kusungunuka mkati mwa mphindi 10. shuga.

3.Magulu angapo am'magazi amatengedwa kuti adziwe kuchuluka kwa shuga pakatha ola limodzi atatha kudya shuga ndikuwonetsedwanso pambuyo pa maola awiri. Nthawi zina, kuyezetsa magazi kwa glucose kumachitika mphindi 30, 60, 90 ndi 120 patatha shuga.

4. Kutanthauzira kwa zotsatira - pamenepa mutha kupanga zojambula zingapo zamagetsi poyeserera. Tikukupatsirani njira zomwe mungatanthauzire zotsatira za mayeso.

• Nthawi zambiri, kuchuluka kwa shuga m'magazi musanamwe madziwo kuyenera kukhala ochepera 6,7 mmol / l, ndipo pambuyo pa mphindi 30-90 mutatenga gawo sayenera kupitirira 11.1 mmol / l, pambuyo pa mphindi 120, magwiritsidwe antchito a Laborator amayenera kuzimiririka 7.8 mmol / L.

• Ngati magazi a shuga asanayesedwe anali m'munsi mwa 6.7 mmol / L, pambuyo pa mphindi 30-90 chizindikirocho chinali chachikulu kuposa 11.1 mmol / L, ndipo pambuyo pa mphindi 120 chatsika pamiyeso yotsika ndi 7.8 mmol / L, ndiye izi zikuwonetsa kuchepa kwa kulolera kwa shuga.

Odwala oterowo amafunikira mayeso owonjezera. • Ngati magazi a shuga asanayesedwe anali m'munsi mwa 6.7 mmol / L, pambuyo pa mphindi 30-90 chizindikirocho chinali chachikulu kuposa 11.1 mmol / L, ndipo pambuyo pa mphindi 120 sichinatsike pamiyeso yotsika ndi 7.8 mmol / L, ndiye izi Zizindikiro zimawonetsa kuti wodwala ali ndi matenda a shuga ndipo amafunikira mayeso owonjezereka ndikuyang'aniridwa ndi endocrinologist.

Kutsimikiza kwamisempha ya magazi, kuchuluka kwa insulin.

Insulin yamagazi imatsimikiziridwa pamimba yopanda kanthu. Pankhaniyi, ndikofunikira kupatula pakumwa zamankhwala zilizonse zomwe zimakhudza kuchuluka kwa mahomoni awa, kutsogoza moyo wabwinobwino: zakudya, ntchito ndi kupuma.

Mitundu ya insulin yofulumira imakhala kuyambira 3 mpaka 28 mcU / ml.

Kuwonjezeka kwa izi kumatha kuwonetsa kukhalapo kwa matenda ashuga kapena metabolic syndrome. Magulu a insulin okwera omwe amakhala ndi shuga wambiri amadziwika ndi matenda a shuga mellitus II a. Mankhwalawa, osakonzekera insulin, zakudya ndi kulemera kwamtunduwu ndizothandiza kwambiri.

Kutsimikiza kwaminyewa ya acetone

Kuphwanya kagayidwe kakang'ono ka glucose kumabweretsa kuti pofuna kukwaniritsa zosowa zamphamvu za thupi, njira yogawa mafuta ochulukirapo imatembenuka, ndipo izi zimapangitsa kuwonjezeka kwa milingo ya matupi a ketone ndi acetone m'magazi. Acetone imakhala ndi poizoni m'thupi, chifukwa impso zimayesera kuuchotsa ndi mkodzo, mapapu amawuyambitsa ndi mpweya.

Kuti mudziwe mkodzo acetone, ndikofunikira kugwiritsa ntchito mawayilesi oyesa omwe amasintha mtundu wawo akakumana ndi urine acetone.

Kuzindikira kwa acetone mu mkodzo kumawonetsa kusayenda bwino kwa matendawa, komwe kumafunikira kuyendera adokotala mwachangu ndi endocrinologist komanso njira zofunikira.

Chithandizo cha matenda a shuga, kuchepa thupi m'matenda a shuga, zakudya za anthu odwala matenda ashuga, mankhwala a hypoglycemic, insulin.

Kuthana ndi matenda ashuga, kudziwa mtundu wa matenda ashuga ndikofunikira. Sikovuta kudziwa njira zamankhwala zodwala kwa odwala omwe ali ndi mtundu wachiwiri wa shuga - ngati chifukwa chachikulu cha kuchuluka kwa shuga ndi kuchepetsedwa kwa insulin, ndiye kuti iyenera kuwonjezereka mothandizidwa ndi mankhwala omwe amachititsa ntchito ya maselo a beta a kapamba, nthawi zina ndikofunikira kuyambitsa kuchuluka kwa insulin kuchokera kunja.

Ndi matenda a shuga a 2, pamafunika njira yokwanira: kuchepetsa thupi,

, kugwiritsa ntchito mankhwala ochepetsa shuga, insulin ngati njira yomaliza.

1. Matenda a shuga a magazi kwa nthawi yayitali. Kupewa kwa chitukuko cha zovuta zomwe zimayamba pang'onopang'ono (matenda ashuga retinopathy, atherosulinosis, microangiopathy, mitsempha) .3. Kupewa kwamatenda a metabolic acute (hypo kapena hyperglycemic coma, ketoacidosis).

Njira ndi njira yokwaniritsira izi pochiza matenda osiyanasiyana a shuga amasiyana kwambiri.

Kuchepetsa thupi mu shuga

Pakadali pano, titha kunena mosapita m'mbali kuti kunenepa kwambiri ndi chimodzi mwazinthu zazikulu zomwe zimayambitsa matenda a shuga. Chifukwa chake, pochiza matenda amtunduwu, matenda a kunenepa kwambiri amafunikira.

Momwe mungapangire kulemera kwanu mu shuga? Zakudya Zachangu pamoyo = zotsatira zomwe mukufuna.

Hypoglycemia ndi hypoglycemic chikomokere

Awa ndi masitepe amachitidwe amodzi. Chowonadi ndi chakuti dongosolo lamanjenje lamkati, mosiyana ndi minofu ina ya thupi, silikufuna kugwira ntchito pa glucose pokhapokha - limangofunika glucose pokhapokha kuti likwaniritse zosowa zamphamvu.

Nthawi zina, ndimakudya osakwanira, regimen yogwiritsira ntchito mankhwala a insulin kapena shuga, kuchepetsa kuchepa kwa glucose pansi pazovuta kwambiri za 3.3 mmol / L ndizotheka. Muzochitika izi, zizindikiro zenizeni zimawonekera, zomwe zimafunikira kuchitapo kanthu kuti zithetsedwe.

Zizindikiro za hypoglycemia: • Kutopa: • Kukulira kudya, Chida chosawoneka bwino chodya china chake kwakanthawi • Kugunda kwamtima mwachangu • Kudzuma kwamilomo ndi nsonga ya lilime • Kutopa kwambiri chidwi • Kulimbitsa kufooka kwapafupipafupi

Ngati simutenga nthawi yake munthawi ya kukula kwa chizindikirocho, ndiye kuti kuwonongeka kwakanthawi kwa ubongo komwe kumatha kusokonezeka. Chithandizo cha hypoglycemia: Tengani mwachangu mankhwala aliwonse omwe amapezeka ndi chakudya chambiri muyezo wa magawo 1-2 amisonkhanowu monga madzi, shuga, shuga, zipatso, mikate yoyera.

Ndi hypoglycemia yayikulu, inunso simudzatha kudzithandiza, mwatsoka, popeza mudzakhala osazindikira. Thandizo kuchokera kunja liyenera kukhala motere: • tembenuzani mutu wanu kumbali kuti muchepetse kusokonekera • ngati pali yankho la glucagon, liyenera kuperekedwa mwachangu posachedwa.

• Mutha kuyika chidutswa cha shuga mkamwa mwa wodwala - pamalo pakati pa m'kamwa ndi m'mano. • Intravenous makonzedwe a shuga kwa wodwala ndikotheka.

Kuimbira ambulansi yokhala ndi vuto la hypoglycemic ndikofunikira.

Hyperglycemia, hyperglycemic coma, ketoacidosis

Kuphwanya malangizo azachipatala, kugwiritsa ntchito insulin mokwanira komanso kusadya bwino kungayambitse shuga m'magazi. Izi zitha kupangitsa kuti madzi atheretu.

Ndipo limodzi ndi madzi mumkodzo, ma elekitirodi oyenera amthupi adzachotsedwamo. Mukanyalanyaza zizindikilo za thupi kwa nthawi yayitali zomwe zikuwonetsa kuchepa kwa matenda ashuga, kumatha kuperewera madzi.

Ngati muli ndi zizindikiro zomwe zafotokozedwa pamwambapa, ngati mwazindikira kuti ali ndi mkodzo mumkodzo wanu kapena mukuununkhira, muyenera kufunafuna thandizo kuchokera kwa endocrinologist wa dokotala wanu kuti musinthe mlingo wa insulin ndikuchita zina kuti mubwezeretse kuchuluka kwa thupi la electrolyte.

Kuyang'anira kugona

Kupitilizabe kupitiliza shuga kumakhala ndi mwayi woti titha kukufotokozerani za kuchuluka kwa shuga ngakhale mutagona.

Ngati muphatikiza zakudya, masewera olimbitsa thupi - kuyang'anira glucose mosalekeza kungathandize kuchepetsa kuchuluka kwa nthawi yomwe mumakhala ndi shuga wambiri kapena wotsika.

Tsopano, tsopano tiyeni tikambirane mwatsatanetsatane za iliyonse.

Fre frere Libre.

Abbott Frechester Libre tsopano yakhala mfundo yatsopano pankhani yogwiritsa ntchito shuga, popereka zambiri kuposa kuchuluka kosavuta kwa shuga m'magazi. Fre frere Libre imakhala yotsika mtengo kuposa njira zina zowonera shuga. Freestyle Libre imapereka kuwunika mwachangu kwa glucose, komwe kumachitika ndikusanthula masensa, m'malo moboola chala.

Chimodzi mwazinthu zomwe CGM ili nacho kuti Fredown Libre ikusowa ndikuwonetsa kwa chenjezo kuti glucose ndiyotsika kwambiri.

Chonde dziwani kuti sensor sikuwerengera kuchuluka kwa shuga m'magazi, koma kuchuluka kwa glucose m'magazi a intercellular.Madzi amtunduwu ndi mtundu wina wamasungidwe am michere, kuphatikiza glucose, wamaselo a thupi lanu. Mitundu yonse yopitilira kagayidwe kachakudya ka glucose imagwiritsa ntchito njirayi poyeza shuga.

Ngakhale kuti mulingo wa shuga womwe umayezedwa mu madzi a interellular umakhala m'njira zambiri pafupi ndi owerenga shuga, nthawi zina pamakhala kusiyana pang'ono. Kusiyanitsa kwa mawonekedwe kungakhale kofunikira kokha ndi hypo kapena hyperglycemia. Pachifukwachi, ndikofunikira kuti muziyeserera magazi a glucose tsiku lonse kuti muone ngati zili zolondola komanso kuyezetsa magazi ngati mukuganiza kuti sensa yolakwika.

Malonda (owerenga)

Ma radio pafupipafupi: 13.56 MHz
Doko Losungira: Micro USB
Miyezo yama glucose am'magazi: 1.1 mpaka 27.8 mmol / L
Miyezo ya ketone ya magazi: 0.0 mpaka 8.0 mmol / L
Mabatire: 1 Li-ion Battery
Moyo wa Battery: Masiku 7 ogwiritsidwa ntchito mwachizolowezi kuchokera ku kubweza
Moyo wautumiki: zaka 3 zogwiritsidwa ntchito mwanjira iliyonse
Miyeso: 95 x 60 x 16 mm
Kulemera: 65g
Kutentha kogwira: 10 ° mpaka 45 ° C
Kutentha Kwakusungirako: -20 ° C mpaka 60 ° C

Freestyle Navigator

Abbott Frechester Navigator ndi Continuous Glucose Monitoring (CGM) yopanga sensor yomwe imafikira ku thupi, transmitter ndi wolandila. Freestyle Navigator yasinthidwa m'malo mwa Newdown Navigator 2 yatsopano.

Sensor imayikidwa pogwiritsa ntchito pulogalamu yapadera yolowera. Sensor ndi transmitter nthawi zambiri zimayikidwa pamimba kapena kumbuyo kwa mkono wakumtunda.

Chida cholowetsera

Chida cholowera chimakupatsani mwayi kuti muike sensor m'malo omwe ma CGM ena sangathe kuyikapo chifukwa chakuletsa. Izi ndichifukwa choti zina ndizazikulu, zina zimafunikira ngodya inayake yoyika.

Olandira FreeStyle Navigator si pampu ya insulini (monga momwe zimakhalira ndi Medtronic CGM ndi machitidwe a Animas Vibe), koma gawo loyimilira lokha lingathe kuyesa magazi a glucose, ndikupangitsa kukhala kosavuta kuyesa CGM.

FreeStyle Navigator imafuna kuyesa kwa mayeso anayi, omwe amayenera kuchitidwa pafupifupi maola 10, 12, 24, ndi 72 atangomvera sensa.

CGM ikudziwitsani ngati kuyesedwa kwa mayeso pakufunika.

Ku deta yaying'ono kwambiri

Wolandirayo akuwonetsa chiwonetsero chamakono mphindi iliyonse. Chonde dziwani kuti wolandirayo ayenera kukhala pakati pa 3 metres ya transmitter kuti mupitirize kupereka deta.

Mutha kuwona graph, kuwerengera kwaposachedwa monga nambala (mwachitsanzo, 8.5 mmol / L), pambuyo pake pali muvi womwe ukusonyeza kuti mulingo wa glucose umasinthira - kumtunda kapena pansi.

Kwa okhutira

Freestyle Navigator

Sensor imayikidwa pogwiritsa ntchito pulogalamu yapadera yolowera. Sensor ndi transmitter nthawi zambiri zimayikidwa pamimba kapena kumbuyo kwa mkono wakumtunda.

Chida cholowetsera

Chida cholowera chimakupatsani mwayi kuti muike sensor m'malo omwe ma CGM ena sangathe kuyikapo chifukwa chakuletsa. Izi ndichifukwa choti zina ndizazikulu, zina zimafunikira ngodya inayake yoyika.

FreeStyle Navigator imafuna kuyesa kwa mayeso anayi, omwe amayenera kuchitidwa pafupifupi maola 10, 12, 24, ndi 72 atangomvera sensa.

CGM ikudziwitsani ngati kuyesedwa kwa mayeso pakufunika.

Ku deta yaying'ono kwambiri

Wolandirayo akuwonetsa chiwonetsero chamakono mphindi iliyonse. Chonde dziwani kuti wolandirayo ayenera kukhala pakati pa 3 metres ya transmitter kuti mupitirize kupereka deta.

Mutha kuwona graph, kuwerengera kwaposachedwa monga nambala (mwachitsanzo, 8.5 mmol / L), pambuyo pake pali muvi womwe ukusonyeza kuti mulingo wa glucose umasinthira - kumtunda kapena pansi.

Sensor data

Kukula kwa Kukula: 1.1 mpaka 27.8 mmol / L
Moyo wa Sensor: Kufikira masiku 5
Kutentha kotentha kwa khungu: 25 ° mpaka 40 ° C

Pulogalamu yotumizira

Kukula: 52 x 31 x 11 mm
Kulemera: 14 g (kuphatikiza batri)
Moyo wa Battery: Pafupifupi masiku 30
Madzi opanda madzi: amatha kukhala m'madzi kwa mphindi 30 pakuzama kwa mita 1

Wolandila deta

Kukula: 63 x 82 x 22 mm
Kulemera: 99g (ndi mabatire a 2 AAA)
Mabatire: Mabatire a AAA x2
Moyo wa Battery: Masiku 60 ogwiritsidwa ntchito mwachizolowezi
Mikwingwirima Yoyesa: Kuwala kwa Freestyle
Nthawi yotsatira: masekondi 7

Makina ogwiritsira ntchito komanso malo osungira

Kutentha kogwira: 4 ° mpaka 40 ° C
Kugwiritsa ntchito komanso kutalika kosungirako: Kutalika kwa nyanja mpaka 3,048 m

Kwa okhutira

Transmitter:

Kukula: 32 x 31 x 11 mm
Mabatire: batire imodzi ya lithiamu CR2032
Moyo wa Battery: Kufikira chaka 1 chazovomerezeka
Njira Zopanda Opanda waya: Kufikira 3 mita

Kukula: 96 x 61 x 16 mm
Kukumbukira Kwambiri: Masiku 60 masiku onse
Mabatire: batire yolumikizira limodzi ya lithiamu-ion
Moyo wa Battery: Kufikira masiku atatu ogwirika
Mikwingwirima Yoyesa: Kuwala kwa Freestyle
Hematocrit: 15 mpaka 65%
Mtundu Wachilengedwe: 10% mpaka 93%

Dexcom G4 Platin CGM

Platin G4 ndi Dexcom Continuous Glucose Monitor (CGM). Platin G4 imaphatikizanso sensa yaying'ono yomwe imafikira mthupi ndikuwunika kuchuluka kwa glucose mosatalikirana kwa mphindi 5 tsiku lonse ndikulondola kwakukulu.

G4 Platinamu imakhala ndi ma alarm omwe amatha kusintha kuti achenjezeni ngati kuchuluka kwa glucose kumakwera kapena kugwa mwachangu kapena kwambiri kapena kutsika kwambiri.

Pulatifomu ya Dexcom G4 imapezeka kwa achikulire ndi ana kuyambira zaka 2.

Zojambula ndi Ubwino wa Dongosolo Lapulogalamu ya Dexcom G4

Kuwerenga glucose mphindi zisanu zilizonse
Mulingo wapamwamba kwambiri
Wolandirayo ali ndi chophimba chautoto - chimathandiza kumvetsetsa zotsatira ndi mawonekedwe mwachidule
Wopepuka kapena Wocheperako wa Alamu
Chidziwitso pakukula msanga kapena kugwa kwa glucose
Transmitter yomwe imatha kufalitsa zowerengera kwa wolandila mpaka 6 m
Zoyenera kuvomerezedwa kuti zizigwiritsidwa ntchito mpaka masiku 7
Kuphatikiza Kwopangidwira ndi Pampu ya Wanyama ya Vibe Insulin
Mapangidwe amakono

Wogulitsira G4 Platinamu ali ndi mawonekedwe okongola, akuda, amakono omwe sangawonekere kwina pafupi ndi kosewerera MP3. Ndiwocheperako poyerekeza ndi Seven Plus ndi 30% opepuka.

G4 Platinamu imapereka chiwonetsero cha kuchuluka kwa glucose ndipo imachita pazenera. Chiwonetserochi chimaphatikizanso zolemba za ola, kupangitsa kuti chidziwike bwino kuposa Seven Plus.

Kuwonjezeka kolondola

G4 Platinamu ndiyolondola kwambiri kuposa CGM Isanu ndi iwiri yapitayo. G4 Platinamu ndi yolondola 20% pazotsatira zonse ndi zolondola 30% kuposa zotsatira 3.3 mmol / L.

Monga machitidwe ena a CGM, G4 iyenera kugwiritsidwa ntchito ngati othandizira ku mita, ndipo osangoikonzanso. Kulondola kwa G4 kumafuna kuchuluka kwa shuga m'magawo 12 aliwonse.

G4 Platinamu imakhala ndi ma alarm ndi zidziwitso zingapo, kuphatikizapo:

Kodi moyo wa sensor ndi transmitter umatenga nthawi yayitali bwanji?

Zomverera za G4 zitha kugwiritsidwa ntchito mpaka masiku 7, pambuyo pake adzafunika zisinthidwe. Wolandila wa G4 Platinow adzawonetsanso ngati sensa ikufunika kusintha posachedwa.

Koma masensa nthawi zambiri amagwira ntchito kwa masiku opitilira 7, ndipo izi zimawonedwa ngati mwayi kwa anthu ambiri, chifukwa masensa ena a CGM amasiya kugwira ntchito atatha masiku angapo.

Chonde dziwani kuti moyo wogwira ntchito ya masensa ndi masiku 7 okha, ndiye kuti kugwiritsa ntchito njira zina ndikuziyambitsa nokha pachiwopsezo.

Anthu ambiri omwe amagwiritsa ntchito masensa a Dexcom masiku 7 oyambilira nthawi zonse amawunika kulondola kwa masensa motsutsana ndi zotsatira zoyeserera zamagazi a glucose ndipo adanenanso kuchuluka kolondola kwambiri. Moyo wa batri wa transmitter ndi miyezi isanu ndi umodzi kuti wotumiza usasinthike.

Zambiri zenizeni za shuga

Munthawi iyi, wolandirira amagwiritsidwanso ntchito, yemwe ali ndi chenera chowonetsa zomwe zimachitika komanso chidziwitso cha glucose yeniyeni. Zambiri zimatumizidwa kuchokera ku sensor mphindi zisanu zilizonse.

Zotsatira za mayeso, mumawona mawonekedwe a graph, zimawonetsa ngati mulingo wa glucose ukusintha kapena kutsika. Zimakuthandizani kuchitapo kanthu: kukhala ndi kuluma kuti mukweze shuga anu wamagazi, kapena jekeseni insulin kuti mupewe hyperglycemia.

Medtronic Enlite Sensor

Ngati mukugwiritsa ntchito pampu ya Medtronic ndipo mukufuna pulogalamu yowunikira mosalekeza, ndiye kuti chisankho chanu choyambirira chikuyenera kukhala sensor ya Enlite.

Dziwani kuti kutha kuyeza kuchuluka kwa glucose ndi gawo limodzi mwazinthu zitatu zazikuluzikulu za CGM. Kuti akwaniritse magwiridwe antchito a CGM, Enlite amagwiritsa ntchito izi:

Kukhazikitsa kwa Sensor

Zomvera zimakhala zosavuta kuyika chifukwa cha chipangizo chonyamula chida chomwe chimayika sensa ya Enlite ndikungodinanso kabatani kokha komanso kutsutsana kochepa. Sensor ya Enlite imakhala chete kwambiri ndipo nthawi zambiri imakhala yopweteka.

Kafukufuku wokhudza kulondola kwa masensa a Enlite adawonetsa kuti kulondola kwa MARD (kusiyana kwathunthu kwa wachibale) ndi 13.6%, komwe ndikodalirika komanso kolondola kwambiri.

Kafukufuku adawonetsanso kuti ma Enlite masensa amapereka chizindikiritso cha 90.2% cha hypoglycemia.

Medtronic Guardian REAL-Time System

Guardian REAL-Time System ndi Medtronic Autonomous Continuous Glucose Monitoring System (CGM), yopangidwa kuti igwiritsidwe ntchito ndi anthu omwe ali ndi jakisoni angapo tsiku lililonse.

Monga ndi ma CGM ena, pulogalamu ya Guardian REAL-Time imakhala ndi zinthu zitatu zazikulu: sensor glucose, yomwe imalumikizidwa ndi thupi, transmitter yolumikiza ndi sensor, komanso polojekiti yomwe imalandira deta yopanda zingwe kuchokera kwa womasulira.

Chonde dziwani: ngati pampu yayambika, kumbukirani kuti mapampu a Medtronic akuphatikizira mwachindunji ndi ma Medgronic CGM masensa ndi ma transmitter ndipo angakupatseni tanthauzo labwino kuposa kukhala ndi dongosolo la CGM.

Njira Yosaoneka Ya Insulin

Ngati mumasewera masewera ndipo nthawi yomweyo muwongolere kuchuluka kwa mahomoni mothandizidwa ndi mayeso a mahomoni, izi zithandizira kuti kayendedwe ka glucose kumisempha ya minofu, ndipo mulingo wake m'magazi utachepa kwambiri, zomwe zikutanthauza kuti mupewe kuchuluka kwa mafuta ochulukirapo chifukwa cha shuga.

Masewera olimbitsa thupi limodzi ndi menyu wopangidwira bwino zimathandizanso kuchotsa kutukuka kwa insulini, ndiko kuti, kukana insulin ndi thupi.

Pogwiritsa ntchito masewera olimbitsa thupi, mafuta owonjezera minofu amawotchedwa ndipo mphamvu zimaperekedwa m'maselo a minofu ndikubwerera. Imalimbikitsa kagayidwe

Kodi kusaloledwa kwa glucose kumatanthauza chiyani ndikuchita nawo?

Kukakhala ndi glucose wambiri m'magazi, zimavuta kuwongolera. Ndipo tsankho la glucose limatha kukula mthupi. Zotsatira zake, munthu amakhalanso pachiwopsezo chotenga matenda a shuga.

Madokotala amatha kudziwa ngati "hypoglycemia" - iyi ndi shuga m'magazi. Zocheperapo kuposa momwe zimakhalira zosakwana 50 mg / dl. Ngakhale pali nthawi zina pamene munthu ali ndi shuga athithithi, pamakhala kulumpha kuchokera kumtunda kupita pamunsi kwambiri, makamaka mukatha kudya.

Glucose amachepetsa maselo a muubongo, kuwapatsa mphamvu kuti agwire ntchito. Ngati glucose wapangidwa kapena wocheperako, ubongo nthawi yomweyo umalangiza thupi.

Chifukwa chiyani shuga wa magazi amatha kukhala wapamwamba? Kupanga kwa insulin kukwera, kuchuluka kwa shuga kumatsika kwambiri. Koma munthu akangolimbikitsidwa ndi china chake chokoma, makamaka makeke okoma (chakudya), ndiye kuti patatha maola 2-3 mulingo wamagazi m'magazi ungachuluke kwambiri. Kusinthasintha koteroko kumatha kupangitsa kuti shuga asalole m'thupi.

Zoyenera kuchita

Kufunika kofunikira kuti musinthe menyu. Musachotseko zakudya zopatsa thanzi, ufa. A endocrinologist athandiza ndi izi. Zitha kuthandizanso kuthana ndi mavuto a njala, omwe amachitika ndi kuchepa kwakukulu kwamagazi a shuga.

Dziwani kuti zoterezi (kuchuluka kwa chilakalaka, kuchuluka kwa mafuta m'thupi, kunenepa kwambiri zomwe simungathe kuzilamulira) sizizindikiro zakukhumudwa, monga angakuuzeni kuchipatala. Ngati mutakhala ndi vuto ili mutha kuyamba kuthandizidwa ndi antidepressants, izi zingayambitse zotsatira zoyipa kwambiri.

Izi zitha kukhala zizindikiro za hypoglemia - kutsika kwa shuga m'magazi - kuphatikiza shuga ndi insulin. Ndikofunikira kubwezeretsa moyenera mahomoni ndikukhazikitsa menyu wathanzi.

Momwe mungadziwire kukana kwa insulin?

Kuti muzindikire kukana kwa thupi ku insulin, ndikofunikira kuchita, choyambirira, kuyezetsa kumawonetsa kuyankha kwa insulini ku glucose. Pakuyesa uku, adotolo azitha kudziwa kuchuluka kwa shuga m'magazi ndi momwe amasinthira maola 6 aliwonse.

Pakatha maola 6 aliwonse, mulingo wa insulin umatsimikiziridwa. Kuchokera pamasamba awa, mutha kumvetsetsa momwe kuchuluka kwa glucose m'magazi kumasinthira. Kodi pali kutumphuka kwakukulu pakukula kwake kapena kuchepa kwake.

Apa milingo ya insulin iyeneranso kukumbukiridwa. Kuchokera momwe zimasinthira, mutha kumvetsetsa momwe insulin imachitikira ndi shuga.

Ngati mulingo wa insulin sutchulidwa, ndiye kuti kuwunika kumeneku kumayendetsedwa, kuyesedwa kotchedwa glucose kulolerana. Zimathandizira kudziwa momwe thupi limazindikirira kuchuluka kwa shuga m'magazi komanso ngati lingathe kuwongolera.

Koma ngati chiwalo chili ndi lingaliro la insulin chitha kutsimikizika pokhapokha pakuwonetsa mwatsatanetsatane.

Ngati pali shuga wambiri

Ndi mkhalidwe uwu wa thupi, zosokoneza mu ubongo zimatha kuchitika. Zimakhala zovulaza ku ubongo pamene kuchuluka kwa glucose kukwera, ndiye kumagwera kwambiri. Kenako mkazi atha kuona zotsatirazi:

Kuda nkhawa
Kugona
Mutu
Kusatetezedwa kwa chidziwitso chatsopano
Zovuta kuyang'ana kwambiri
Ludzu lalikulu
Nthawi zambiri zimbudzi zoyimbira
Kudzimbidwa
Ululu m'matumbo, m'mimba

Magazi a glucose pamtunda wa mayunitsi 200 ndi chizindikiro cha hyperglycemia. Matendawa ndi gawo loyamba la matenda ashuga.

Glucose wotsika kwambiri

Itha kukhala yotsika nthawi zonse kapena kutsika kwambiri mukatha kudya. Kenako, mwa mkazi, madokotala amayang'ana zizindikiro zotsatirazi.

Nthawi yochita masewera olimbitsa thupi - kugunda kwamphamvu kwambiri komanso pafupipafupi
Vuto lakuthwa, losasinthika, nkhawa, komanso mantha
Kupweteka kwa minofu
Chizungulire (nthawi zina kuchita mseru)
Kupweteka kwam'mimba (m'mimba)
Kufupika komanso kupumira mofulumira
Pakamwa ndi mphuno zimatha kukhala dzanzi
Zala zam'manja zonse zimatha kulira
Kuzindikira ndi kulephera kukumbukira, kukumbukira kumatha
Kusintha kwa malingaliro
Misozi, kusokoneza

Kupatula pazizindikirozi, mungadziwenso bwanji kuti mumakhala ndi shuga wambiri kapena insulin?

Momwe mungadziwire kuchuluka kwa insulin m'thupi?

Izi ndizovuta kwambiri kuposa kudziwa kuchuluka kwa shuga, chifukwa ma insulin amatha kusiyanasiyana. Tikudziwitsani insulin.

Kuwunikira kwa kuchuluka kwa insulin komwe kumachitika pamimba yopanda kanthu ndi magawo 6-25. Mlingo wa insulin 2 maola mukatha kudya umafika magawo 6-35.

Magulu owopsa

Ngati mayi ali ndi insulini yambiri pamimba yopanda kanthu, izi zitha kutanthauza kuti ali ndi ma polycystic ovaries.

Vutoli limatha kuchitika mwa azimayi omwe akuyembekeza kusamba. Itha kutsagana ndi kuwonjezeka kwakukulu kwa kulemera, makamaka m'mimba ndi m'chiuno.

Mlingo wabwinobwino wa insulini uyenera kudziwika ndikuwongoleredwa kuti usachire mopitirira muyeso ndikuwongolera kuwonda.

Njira ina yothanirana ndi glucose

Ingoyesani mahomoni kuti mupeze shuga yanu pogwiritsa ntchito kuchuluka kwa mahomoni ena. Makamaka, hemoglobin A1C level. Hemoglobin imeneyi imapereka mpweya m'maselo ofiira a m'magazi - magazi.

Dziwani kuti ngati thupi lanu silikuyang'ananso kuchuluka kwa shuga m'magazi, ndiye kuti hemoglobin imayankhanso kuwonjezeka kumeneku.

Kuyesedwa kwa timadzi timeneka kumathandizira kudziwa ngati thupi lanu lingathebe kugwiritsira ntchito glucose kapena walephera.

Chiyesocho ndicholondola kwambiri kotero kuti mutha kudziwa momwe mulingo wambiri wa shuga m'masiku 90 apitawa.

Ngati matenda a shuga apanga kale, mulingo wa hemoglobin angakuuzeni ngati mukufunikira kusintha zakudya zanu. Kuchokera ku hormone iyi, mutha kudziwa ngati zakudya zomwe mumadya zathandizira kuti shuga yoletsa glucose ipange m'thupi.

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Ndikofunikira kudziwa!

Zizindikiro za Neuroglycopenic chifukwa cha kuchepa kwa kuperekera kwa glucose ku ubongo ziyenera kulekanitsidwa ndi zomwe zimagwirizanitsidwa ndi kukondoweza kwa dongosolo la sympathoadrenal. Zoyambirira zimawonetsedwa ndi mutu, kulephera kukhazikika, kusokonezeka, zosayenera.