Ku Russian Federation apeza njira yatsopano yochizira matenda ashuga

Tikukulimbikitsani kuti mudzidziwe bwino ndi nkhaniyi yomwe ili pamutuwu: "Russia yapeza njira yatsopano yochizira matenda ashuga" ndi ndemanga kuchokera kwa akatswiri. Ngati mukufuna kufunsa funso kapena kulemba ndemanga, mutha kuchita izi pansipa, nkhaniyo itatha. Katswiri wathu wamtundu wa endoprinologist adzakuyankhirani.

Ku Russia, adapeza njira yatsopano yochizira matenda ashuga

M'zaka zikubwerazi, odwala aku Russia azidziwa zamakono zam'manja zochizira matenda a shuga, zomwe zingawathandize kusiya jakisoni wa insulin, atero a Minister of Health Veronika Skvortsova.
“Matekinoloje a Cellular ochizira matenda ashuga. Titha kusintha ma cell a pancreatic omwe amapanga insulini. Amadziphatikiza ndi matendawa ndipo amayamba kupanga iwo eni, ”akutero Skvortsova poyankhulana ndi Izvestia.

Sizinatetezeke kunena kuti njira iyi imalola anthu odwala matenda ashuga kuiwala za jakisoni kwamuyaya.

"Ndikufuna izi (kukhazikitsa mankhwala atsopano - pafupifupi. Mkonzi.) Kukhala wokhazikika. Komabe pali ntchito yofunika kuigwira. Ndikosavuta kumvetsetsa poyesa kuti maselo awa atenga nthawi yayitali bwanji. Mwina uwu ndi maphunziro, "ndunayo idalongosola.

"Talandira kale cartilage kuchokera kumaselo am'munthu, omwe atha kugwiritsidwa ntchito pobwezeretsa mawonekedwe athu. Ndi chithunzithunzi cha khungu la munthu, ndizofunikira pakachiza pamatenda, "adatero Skvortsova.

Ku Russia, kuyesa koyesa kwa maselo am'mimba kumakwaniritsidwa, komwe kumayang'ana mozungulira mu gawo lakumaso la ubongo ndikunyowetsa gawo lomwe lachitika m'masiku ochepa.

"Izi zikutipangitsa kuti tichite bwino kwambiri sitiroko, matenda oopsa, kapena matenda ena," adatero Skvortsova.

Lumikizani nkhani: http://www.mk.ru/science/article/2013/07/03/878571-novaya-vaktsina-zastavlyaet-organizm-diabetikov-vyirabatyivat-insulin-samostoyatelno.html

Kwenikweni nkhani zokha.

Ma syringe adzakhala chinthu chakale - katemera watsopano wa DNA wayesedwa bwino mwa anthu

Chifukwa chopanga njira yatsopano yothandizira, anthu omwe ali ndi matenda amtundu wa 1 posachedwa amatha kuiwala za syringes ndi jakisoni wokhazikika wa insulin. Pakadali pano, Dr. Lawrence Steinman ochokera ku yunivesite ya Stanford adati njira yatsopano yothandizira matenda a shuga 1 yayesedwa bwino mwa anthu ndipo angagwiritsidwe ntchito kwambiri pochiza matendawa mtsogolo.

matenda a shuga 1 matenda a shuga a insulin lawrence steinman katemera Lawrence steinman neurology
Lawrence Steinman, M.D./ Stanford University
Katemera yemwe amatchedwa "reverse katemera" amagwira ntchito mwa kutsinikiza chitetezo cha mthupi pa DNA, zomwe zimapangitsa kuti insulini ipangidwe. Kukula kwa yunivesite ya Stanford ikhoza kukhala katemera woyamba wa DNA padziko lapansi yemwe angagwiritsidwe ntchito pochiritsa anthu.

“Katemera uyu amatengera njira ina. Limaletsa mayankho enieni a chitetezo cha mthupi, ndipo sizimapanga mayankho achindunji ngati katemera wamba kapena katemera wa polio, "atero a Lawrence Steinman.

Katemera anayesedwa pagulu la odzipereka 80. Maphunzirowa adachitika zaka ziwiri ndikuwonetsa kuti odwala omwe amalandila chithandizo malinga ndi njira yatsopanoyo akuwonetsa kuchepa kwa ntchito yama cell omwe amawononga insulin mthupi. Nthawi yomweyo, kunalibe zotsatila atamwa katemera.

Monga momwe dzinalo likunenera, katemera wothandizira sanapangidwe kuti apewe matenda, koma kuthandiza matenda omwe alipo.

Asayansi, atazindikira mitundu iti ya leukocytes, "asirikali" oyamba a chitetezo cha mthupi, omwe amagwidwa ndi kapamba, apanga mankhwala omwe amachepetsa kuchuluka kwa maselo amenewa m'magazi osakhudza mbali zina za chitetezo cha mthupi.

Ophunzira nawo pa mayeso kamodzi pa sabata kwa miyezi itatu adalandira jakisoni wa katemera watsopano. Mofananamo, anapitiliza kupeleka insulin.

Gulu lolamulira, odwala omwe amalandira jakisoni wa insulin amalandira mankhwala a placebo m'malo mwa katemera.

Omwe amapanga katemerayu akuti mgulu loyesera lomwe limalandira mankhwalawo, panali kusintha kwakukulu pakugwira ntchito kwa maselo a beta, omwe pang'onopang'ono adabwezeretsa kutulutsa insulin.

"Tatsala pang'ono kukwaniritsa maloto a dotolo aliyense: taphunzira kuyesa kuzimitsa kachipangizidwe ka chitetezo chathupi osakhudza kugwira ntchito kwake konse," anatero a Lawrence Steinman, m'modzi mwa olemba zomwe apezazi.

Matenda a shuga a Type 1 amadziwika kuti ndi matenda oopsa kwambiri kuposa matenda a shuga a "mnzake".

Mawu oti shuga pawokha amatengedwa kuchokera ku mawu achi Greek akuti "diabayo," omwe amatanthauza "ndikudutsa kena kake,", "kuyenda". Dokotala wakale Areteus wa ku Cappadocia (30 ... 90 AD) adawonera odwala polyuria, omwe adalumikizidwa ndi zakuti madzi omwe amalowa mthupi amayenda kudzera mwa iwo ndipo amawonetsedwa osasinthika. Mu 1600 AD e. shuga idawonjezeredwa ku liwu loti mellitus (kuchokera lat. mel - uchi) kutanthauza shuga ndi mkoma wokoma wa mkodzo - shuga.

Matenda a shuga a insipidus anali odziwika kale ngati zakale, koma mpaka m'zaka za zana la 17 kunalibe kusiyana pakati pa matenda ashuga ndi insipidus. Mu XIX - koyambirira kwa zaka za XX, ntchito yochulukirapo pa matenda a shuga insipidus idawonekera, kulumikizana kwa matendawa ndi matenda am'mimba am'mimba komanso chithokomiro cha positi chakakhazikitsidwa. M'mafotokozedwe azachipatala, mawu akuti "matenda ashuga" nthawi zambiri amatanthauza ludzu ndi matenda ashuga (matenda ashuga komanso matenda a shuga), komabe "pamadutsa" - matenda a shuga a phosphate, matenda a impso (chifukwa cha malire ochepa a shuga, osayenda ndi matenda ashuga), ndi zina zambiri.

Mwachindunji lembani 1 shuga mellitus ndi matenda omwe chizindikiritso chake chachikulu ndi hyperglycemia - shuga wambiri, polyuria, chifukwa chomwe mumamva ludzu, kuchepa thupi, kulakalaka kwambiri, kapena kusowa kwake, thanzi labwino. Matenda a shuga amapezeka matenda osiyanasiyana omwe amatsogolera kuchepa kwa kaphatikizidwe ndi katemera wa insulin. Udindo wa cholowa chofufuzira ukufufuzidwa.

Matenda a shuga amtundu wa 1 amatha kukula pazaka zilizonse, koma anthu azaka zazing'ono (ana, achinyamata, achikulire osakwana 30) nthawi zambiri amakhudzidwa. Makina a pathogenetic omwe amapanga chitukuko cha matenda a shuga 1 amachokera pa kuperewera kwa insulin yopanga ma cell a endocrine (β-cell of islets of Langerhans of the pancreas), omwe amayamba chifukwa cha kuwonongeka kwawo motsogozedwa ndi zinthu zina za pathogenic (matenda a virus, nkhawa, matenda a autoimmune ndi ena).

Mtundu woyamba wa matenda a shuga umakhala ndi 10% ya matenda onse a shuga, nthawi zambiri amakula ubwana kapena unyamata. Njira yayikulu yothandizira ndi majakisoni a insulin omwe amateteza kagayidwe ka wodwala. Ngati sichichiritsidwenso, matenda ashuga amtundu wa 1 amakula msanga ndipo amadzetsa mavuto akulu, monga ketoacidosis ndi chikomokere matenda a shuga, zomwe zimapangitsa kuti wodwalayo afe.

ndipo tsopano zowonjezera mwachidule. Inenso ndili ndi matenda ashuga kwa zaka 16. zinandibweretsera mavuto ambiri m'moyo, ngakhale zinali zofunikanso. Popanda matenda, sindikadakhala kuti ndine ndani. Ndikadapanda kuphunzira kudziletsa, sindikadakhala okhwima pamaso pa anzanga. Inde, zinthu zambiri. Aaah, ndikupemphera kuti akatswiri azamalonda omwe amapanga ndalama zochulukirapo pamwayiwu asawononge nkhaniyi. Ndikulakalaka odwala onse atha kukhala ndi moyo mpaka nthawi yabwino yomwe matendawa achira. anyamata ophika onse))

Asayansi aku Russia adabwezeretsa makoswe a pancreatic diabetes

Zotsatira za phunziroli zithandizira kukonza njira zatsopano zochizira matenda ashuga.
Chithunzi sipa / pixabay.com.

Ofufuza ochokera ku Ural Federal University, pamodzi ndi anzawo ochokera ku Ural Institute of Immunology and Physiology (IIF) ya Ural Branch ya Russian Academy of Science, adayesa momwe ntchito zobwezeretsedwera zimakhudzira zikondwererozi. Zotsatira za phunziroli zithandiza kupanga njira zatsopano zochizira matenda ashuga, akutero akatswiri.

"Tinaganiza zopanga njira zatsopano zopewera ndi kuchiza matenda ashuga pogwiritsa ntchito mankhwala opangidwa ndi mankhwala othandizira odwala matenda ashuga. Zinali zofunikira kumvetsetsa momwe zinthuzi zimapangidwira pama cell, minofu, ziwalo komanso chamoyo chonse, "watero wolemba kafukufukuyu, Doctor of Biological Sayansi Irina Danilova.

Kumbukirani kuti mtundu woyamba wa shuga ndi matenda osachiritsika omwe kapamba sangapange insulin. Zotsatira zake, kuchuluka kwa shuga m'magazi kumakwera, chifukwa choti ziwalo zosiyanasiyana ndi minyewa yake imawonongeka pang'onopang'ono. Chifukwa chake, kuchuluka kwa shuga m'magazi kumapangitsa kupsinjika kwa oxidative - kuwonongeka kwa mamolekyulu a mapuloteni, lipids, DNA mwa ma radicals aulere.

Njira ina yofunika yowonongeka kwa minyewa m'matenda a shuga ndi ma enzymatic glycosylation (glycation) a mapuloteni. Umu ndi momwe gululi limagwirira ntchito limodzi ndi magulu a amino mapuloteni popanda kutenga michere. M'matenda a anthu athanzi, izi zimachitika pang'onopang'ono. Koma ndi glucose okwera, njira ya glycation imathandizira, ndikuwononga minofu.

Anthu odwala matenda amtundu wa 1 amafuna jakisoni wa insulin tsiku lililonse. Madokotala, akatswiri azamankhwala ndi mafakitale akufunafuna mankhwala omwe angayambitse kusinthika kwa maselo a pancreatic owonongeka kuti athe kupanga kachiwiri mahomoni awa pamlingo woyenera. Kuti achite izi, asayansi adaganiza zofufuza momwe zingapangidwire mankhwala omwe amaphatikiza kuthekera kukonza metabolic (oxidative nkhawa ndi glycation ya mapuloteni) ndi zovuta za immunological (kutupa poyankha) mu matenda osokoneza bongo.

Poyamba, asayansi adasankha ma heterocyclic ophatikizira 1,3,4-thiadiazine, omwe ali ndi antioxidant komanso ntchito yonyansa. Kenako kuyesa kunachitika mu makina a labotale omwe ali ndi matenda a shuga a mellitus, omwe adawonetsedwa pazopezeka.

"Tinayesetsa kukonza matenda okhudzana ndi matenda ashuga omwe ali ndi 1,3,4-thiadiazine. Zotsatira zake, kuchuluka kwa glucose ndi glycosylated hemoglobin m'magazi a makoswe kunachepa, ndipo zomwe zimapangitsa insulin kuchuluka. Mankhwala omwe atsekedwa omwe atseka njira zomwe tazitchulazi atha kukhala mankhwala ogwiritsira ntchito mankhwalawa, "Danilova adamaliza.

Nkhani yasayansi yochita kafukufuku waku Russia imasindikizidwa mu Biomedicine & Pharmacotherapy.

Tikuwonjezera kuti asayansi akupeza njira zina zolimbana ndi matenda amtundu wa shuga. Mwachitsanzo, kusamutsa majini, komanso peptide immunotherapy, posachedwa amatha kubwezeretsa jakisoni wokhazikika wa insulin.

M'zaka zikubwerazi, odwala aku Russia azidziwa zamakono zam'manja zochizira matenda a shuga, zomwe zingawathandize kusiya jakisoni wa insulin, atero a Minister of Health Veronika Skvortsova.

“Matekinoloje a Cellular ochizira matenda ashuga. Titha kusintha ma cell a pancreatic omwe amapanga insulini. Amadziphatikiza ndi matendawa ndipo amayamba kupanga iwo eni, ”akutero Skvortsova poyankhulana ndi Izvestia. Sizinatetezeke kunena kuti njira iyi imalola anthu odwala matenda ashuga kuiwala za jakisoni kwamuyaya. "Ndikufuna izi (kukhazikitsa mankhwala atsopano - pafupifupi. Mkonzi.) Kukhala wokhazikika. Komabe pali ntchito yofunika kuigwira. Ndikosavuta kumvetsetsa poyesa kuti maselo awa atenga nthawi yayitali bwanji. Mwina uwu ndi maphunziro, "ndunayo idalongosola. "Talandira kale cartilage kuchokera kumaselo am'munthu, omwe atha kugwiritsidwa ntchito pobwezeretsa mawonekedwe athu. Ndi chithunzithunzi cha khungu la munthu, ndizofunikira pakachiza pamatenda, "adatero Skvortsova. Ku Russia, kuyesa koyesa kwa maselo am'mimba kumakwaniritsidwa, komwe kumayang'ana mozungulira mu gawo lakumaso la ubongo ndikunyowetsa gawo lomwe lachitika m'masiku ochepa. "Izi zikutipangitsa kuti tichite bwino kwambiri sitiroko, matenda oopsa, kapena matenda ena," adatero Skvortsova.

Skvortsova adalengeza kupambana kwa khansa mzaka 5

Ukwati ndi abwenzi apamtima amateteza ku matenda a dementia

Asayansi aku Russia apanga ukadaulo wothandizira matenda ashuga

Tekinoloje yatsopano imakupatsani mwayi wokonzanso kapamba. M'malo mwake - mubwezeretse.

Institute of Development Biology Koltsova (Moscow) akukonzekera kugonjera ku Unduna wa Zaumoyo ukadaulo wobwezeretsa ntchito za kapamba, watero Director Director a A. Vasiliev. Ndi zakuchiritsa matenda ashuga.

Pamsonkano "Biomedicine-2016" ku Novosibirsk, wasayansiyo ananena kuti asayansi atha kupeza maselo omwe amapanga insulin kuchokera m'maselo a anthu. Pambuyo pobweretsa maselo ku mbewa zaku labotale, zidapezeka kuti maselo amayankha kuchuluka kwa glucose. Zimasunthira kapamba, kumadzaza ndikumanganso.

Lamulo pa Biomedical Cellular Products (lidzayamba kugwira ntchito mchaka cha 2017) limakhazikitsa njira zothandizira kupanga zinthu zama cellular, kafukufuku wamakedzana komanso zamankhwala komanso kulembetsa boma. Malinga ndi A. Vasiliev, kulembetsa kwa njira yothandizira kubwezeretsa pancreatic kudzafunika kukhazikitsidwa kwa malamulo 40. "Padzakhala chilichonse: zinthu zopanda moyo, komanso zaukadaulo, ndi zina zonse," wasayansi anatero.

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20 5 259 Pazenera

Wodwala mwana wazaka 11. Odwala 2 years. Vomerezani kukhala otulutsa.

Ku Russia, adapeza chithandizo chatsopano cha matenda ashuga

M'zaka zikubwerazi, odwala aku Russia azidziwa zamakono zam'manja zochizira matenda a shuga, zomwe zingawathandize kusiya jakisoni wa insulin, atero a Minister of Health Veronika Skvortsova. Zimanenedwa ndi RIA Novosti.

Veronika Skvortsova adanena kuti sizotheka kunena motsimikiza kuti njira yothandizira matenda ashuga ndi matekinoloje a m'manja imalola anthu odwala matenda ashuga kuiwala za jakisoni kwamuyaya.

"Titha kusintha maselo a pancreatic omwe amapanga insulini." Amadzilowetsa m'matumbo a gland ndikuyamba kupanga mahomoni nawonso. Ndikufuna kukhala nthawi imodzi. Komabe pali ntchito yofunika kuigwira. Ndikosavuta kumvetsetsa poyesa kuti maselo awa atenga nthawi yayitali bwanji. Mwina ndi momwemo, "Skvortsova adatero poyankhulana ndi atolankhani.

_{Maumwini onse ndi otetezedwa. Mukasindikiza, kulumikizidwa ku tsamba la IA "Grozny-tseb" ndikofunikira.}

Information Agency "Grozny-dziwitsani"

Kodi mwapeza cholakwika m'mawuwo? Sankhani ndi mbewa ndikusindikiza: Ctrl + Lowani

1. 
   Nikberg, I.I. Matenda a shuga / I.I. Nickberg. - M.: Zdorov'ya, 2015. - 208 c.
2. 
   Bobrovich, P.V. Mitundu yamagazi 4 - njira 4 kuchokera ku matenda ashuga / P.V. Bobrovich. - M.: Potpourri, 2016 .-- 192 p.
3. 
   Russell Jesse Mtundu 1 wa Matenda A shuga, Buku la Demand -, 2012. - 250 c.

Ndiloleni ndidziwitse. Dzina langa ndi Elena. Ndakhala ndikugwira ntchito ya endocrinologist kwa zaka zoposa 10. Ndikukhulupirira kuti pakadali pano ndili katswiri pantchito yanga ndipo ndikufuna kuthandiza alendo onse omwe amapezeka pamalowo kuti athetse zovuta osati ntchito. Zinthu zonse za tsambalo amazisonkhanitsa ndikuzikonza mosamala kuti athe kufotokoza zambiri zofunikira. Musanagwiritse ntchito zomwe zikufotokozedwa pa webusayiti, kukambirana ndi akatswiri ndizofunikira nthawi zonse.