The mankhwala INSULIN LIZPRO - malangizo, ndemanga, mitengo ndi analogies

Lyspro insulin ndi analogue ya insulin ya anthu. Lyspro insulin imasiyana ndi insulin ya anthu motsatizana kwa proline ndi lysine amino acid zotsalira pamalo 28 ndi 29 a insulin B. Lyspro insulin imayang'anira kagayidwe ka glucose. Komanso insulin lyspro imakhala ndi anti-catabolic ndi anabolic zotsatira zosiyanasiyana za thupi. Mu minofu yam'mimba, zomwe zimapangidwa ndi glycogen, mafuta acids, glycerol imawonjezeka, pali kuwonjezeka kwa kumwa kwa amino acid ndi kaphatikizidwe kamapuloteni ambiri, koma izi zimachepetsa gluconeogenesis, glycogenolysis, lipolysis, ketogeneis, katemera wa protein ndi kutulutsidwa kwa ma amino acid. Lyspro insulin yawonetsedwa kuti ikufanana ndi insulin ya anthu. Poyerekeza ndi kufupikitsa insulini kukonzekera, inspro insulin imadziwika ndi kuyambanso mwachangu komanso kutha kwake. Izi ndichifukwa chakuchulukitsidwa ochulukirapo kuchokera ku malo ochepera chifukwa chosungidwa ndi monomeric kapangidwe ka mamolekyulu a lyspro insulin mu yankho. Mphindi 15 pambuyo pa kayendetsedwe ka subcutaneous, mphamvu ya insulin lispro imawonedwa, mphamvu yayikulu imawonedwa pakati pa maola 0.5 ndi 2,5, kutalika kwa nthawi ndi maola 3-4. Odwala omwe ali ndi mtundu woyamba 1 ndi mtundu 2 matenda a shuga, hyperglycemia yomwe imatha chakudya itachepa kwambiri mukamagwiritsa ntchito lyspro insulin poyerekeza ndi insulin yaumunthu. Kwa odwala omwe amalandila insulin ya basal komanso yochepa, mlingo wa mankhwalawa umayenera kusankhidwa kuti akwaniritse kuchuluka kwa shuga tsiku lonse. Kutalika kwa nthawi ya insulin lispro, monga momwe akukonzekera insulin yonse, imatha kukhala yosiyanasiyana mwa odwala kapena nthawi zosiyanasiyana mwa munthu yemweyo ndipo zimatengera mlingo, magazi, jakisoni, malo olimbitsa thupi komanso kutentha kwa thupi. Pharmacodynamics ya insulin lyspro mwa ana ndiofanana ndi zomwe zimawonetsedwa mwa akulu. Odwala omwe ali ndi matenda a shuga a mtundu wachiwiri omwe amalandila Mlingo wambiri wa sulfonylurea, kuwonjezera kwa insulin kumapangitsa kutsika kwa hemoglobin wa glycosylated. Lyspro insulin mankhwala a odwala omwe ali ndi mtundu woyamba 1 ndi matenda a 2 amathandizana ndi kuchepa kwa ziwopsezo za nocturnal hypoglycemia. Kuyankha kwa glucodynamic ku lyspro insulin palokha popanda chiwindi kapena impso.
Mothandizidwa ndi subcutaneally, inshuwaransi ya lyspro imatengedwa mwachangu ndikufika m'magazi ambiri pambuyo pa 30 - 70 mphindi. Kuchulukitsa kwa kugawa kwa insulin lispro ndi 0,26 - 0,36 l / kg ndipo ndikofanana ndi kuchuluka kwa magawidwe wamba a insulin. Hafu ya moyo wa insulin lyspro ndi subcutaneous makonzedwe pafupifupi ola limodzi. Odwala omwe ali ndi vuto la chiwindi ndi / kapena impso, chiwopsezo chambiri cha inshuwaransi ya inspro chimafananizidwa ndi insulin.

Type 1 shuga mellitus (wodalira insulini), amene amafunikira insulini kuti azikhalanso ndi shuga wamagazi, kuphatikiza ndi zovuta zina za insulin, kuchepa kwa insulini (kuthamanga kwa insulini), postprandial hyperglycemia, yomwe singathe kukonza ma insulin ena.
Type 2 shuga mellitus (osadalira insulini), wofuna insulini kuti akhalebe wamagulu am'magazi am'magazi: kuyamwa kwamankhwala ena kukonzekera kwa insulin, kukana kwa mankhwala a hypoglycemic, matenda osadziwika a postprandial hyperglycemia, omwe ali ndi matenda osokoneza bongo.

Lyspro insulin makonzedwe ndi mlingo

Lyspro insulin imayang'aniridwa subcutaneous, mu mnofu mwamitsemphindi 5 mpaka 15 chakudya musanadye. Mlingo wothandizira ndi njira yoyendetsera amakhazikitsidwa payekhapayekha.
Lyspro insulin ikhoza kutumikiridwa musanadye. Ngati ndi kotheka, Lyspro insulin ikhoza kutumikiridwa patangotha ​​chakudya.
Wodwala ayenera kuphunzitsidwa njira yolondola ya jakisoni. Mosadukiza amayenera kubayidwa m'ntchafu, phewa, m'mimba kapena matako. Masamba a jakisoni ayenera kusinthidwa kuti malo omwewo asagwiritsidwerenso osaposa kamodzi pamwezi. Mothandizidwa ndi insulin lyspro, muyenera kusamala kuti mankhwalawo asatenge magazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa.
Ngati ndi kotheka (matenda pachimake, ketoacidosis, nthawi pakati pa ntchito kapena nthawi ya postoperative), inspro insulin ikhoza kutumikiridwa kudzera m'mitsempha.
Ndikofunika kuyang'anitsitsa njira yoyendetsera, yomwe imapangidwira njira ya insulin lispro.
Kusintha kwa magazi kungafunike poika odwala ku lyspro insulin ndi insulin yokonzekera mwachangu yochokera ku nyama. Zosintha mu zochitika, mtundu (wopanga), mtundu, mitundu, njira ya insulin ingapangitse kufunika kwa kusintha kwa mlingo. Kusamutsa odwala kuchokera ku mtundu umodzi wa insulin kupita ku wina kuyenera kuchitika moyang'aniridwa ndi achipatala, ndipo odwala omwe amalandila insulin tsiku lililonse magawo opitilira 100 kuchipatala.
Ndi kupsinjika kwamaganizidwe, panthawi ya matenda opatsirana, pakulowerera kwakumwa kwa mankhwala omwe ali ndi ntchito ya hyperglycemic (glucocorticoids, mahomoni a chithokomiro, thiazide diuretics, njira zakulera pakamwa), ndikuwonjezereka kwa chakudya chamagulu, chakudya, insulin chitha kuchuluka.
Kufunika kwa insulin kumatha kuchepa ndikuchepa kwa kuchuluka kwa chakudya chamagulu mu chakudya, chiwindi ndi / kapena kulephera kwa impso (chifukwa cha kuchepa kwa gluconeogeneis ndi insulin metabolism), zochitika zolimbitsa thupi zowonjezera, kugwiritsa ntchito mankhwala owonjezera ndi hypoglycemic shughuli (osasankha beta-blockers, monoamine oxidase inhibitors, sulfonamides). Koma mwa odwala omwe ali ndi vuto losatha la chiwindi, kuchuluka kwa insulin kungayambitse kuchuluka kwa insulin.
Mikhalidwe yomwe zizindikiro zoyambilira za hypoglycemia sizitha kutchulidwira ndipo zopanda tanthauzo zimaphatikizapo chithandizo chokwanira ndi insulin, kupitilirabe kwa matenda a shuga, matenda amanjenje mu matenda a shuga, komanso kugwiritsa ntchito mankhwala, monga beta-blockers.
Odwala omwe ali ndi hypoglycemia, atasamutsidwa kuchokera ku insulin ya nyama kupita ku insulin yaumunthu, zizindikiro zoyambirira za hypoglycemia zitha kusiyana ndi omwe adakumana ndi chithandizo ndi insulin yawo yapitayi. Kusintha kosasinthika kwa hyperglycemic kapena hypoglycemic kungayambitse kusokonezeka kwa chikumbumtima, kwa omwe, imfa.
Kugwiritsa ntchito Mlingo wosakwanira kapena kusiya kulandira chithandizo, makamaka kwa odwala omwe ali ndi matenda a shuga 1, kungayambitse matenda a hyperglycemia ndi matenda ashuga a ketoacidosis, omwe angawononge moyo wa wodwalayo.
Kusintha kwa Mlingo kungafunike ngati chakudya chazomwe wodwala azisintha kapena zolimbitsa thupi. Kuchita masewera olimbitsa thupi mutangotha ​​kudya kumatha kuwonjezera ngozi ya hypoglycemia.
Mukamagwiritsa ntchito insulin pokonzekera limodzi ndi mankhwala a gulu la thiazolidinedione, chiopsezo chotenga matenda a edema ndi mtima osalephera chimawonjezeka, makamaka kwa odwala omwe ali ndi matenda amtima komanso kupezeka kwa zinthu zomwe zingayambitse matenda osalephera a mtima.
Kuthamanga kwa zomwe zimachitika komanso momwe wodwalayo amatha kukhazikika angayikidwe ndi hyperglycemia kapena hypoglycemia, yomwe imalumikizidwa ndi njira yolakwika ya insulin lispro, yomwe imatha kukhala yowopsa nthawi zomwe maluso amenewa ndi ofunikira kwambiri (mwachitsanzo, kugwiritsa ntchito makina, magalimoto oyendetsa ndi ena). Odwala ayenera kusamala kuti apewe hypoglycemia poyendetsa galimoto kapena kugwira ntchito komwe pakufunika chidwi chochulukirapo komanso kuthamanga kwa zochitika zama psychomotor. Izi ndizofunikira kwambiri kwa odwala omwe alibe kapena kuchepera kumverera kwa zizindikiro za hypoglycemia kapena omwe zochitika za hypoglycemia nthawi zambiri zimawonedwa. Muzochitika izi, kuyenera kogwira ntchito zomwe zimafunikira chidwi komanso kuthamanga kwa zochitika zama psychomotor, kuphatikizapo kuyendetsa galimoto, kuyenera kuwunikiridwa.
Contraindication
Hypersensitivity, hypoglycemia.

Mimba komanso kuyamwa

Pakadali pano, palibe zotsatira zosasangalatsa za Lyspro insulin pa mimba kapena thanzi la mwana wosabadwa ndi wakhanda. Kafukufuku wothandiza wa matenda mpaka pano sanachitike. Pakati pa nthawi yayitali, chinthu chachikulu ndikukhazikitsa chitetezo chabwino cha glycemic mwa odwala omwe ali ndi matenda a shuga omwe amalandila insulin. Kufunika kwa insulin panthawi yapakati kumachepa mu trimester yoyamba ndikuwonjezeka trimesters yachiwiri ndi yachitatu. Kufunika kwa insulini kumatha kuchepa kwambiri pakubadwa kwa mwana ndipo pambuyo pake. Odwala omwe ali ndi matenda ashuga ayenera kufunsa dokotala ngati ali ndi pakati kapena akufuna kukhala ndi pakati. Panthawi yapakati mwa amayi omwe ali ndi matenda ashuga, chinthu chachikulu ndikuwunika shuga ndi thanzi lathunthu. Sizikudziwika ngati lyspro insulin imadutsa kwambiri mkaka wa m'mawere. Odwala omwe ali ndi matenda a shuga mellitus nthawi yoyamwitsa, kusintha kwa insulin ndi / kapena zakudya kungafunike.

Zotsatira zoyipa za insulin lyspro

Hypoglycemia (kuchuluka thukuta, pallor, palpitations, kugona kusokonezeka, kugwedezeka, mitsempha), hypoglycemic precoma ndi chikomokere (kuphatikizapo zotsatira zakupha), zolakwika zosakhalitsa, zolimbana ndi zovuta zina (zam'deralo - kufupika, kutupa, kuyabwa pamalowo jakisoni, generalized - urticaria, kuyabwa mthupi lonse, angioedema, kupuma movutikira, kutentha thupi, kuchepa kwa magazi, kuchuluka thukuta, tachycardia), lipodystrophy, edema.

Kuchita kwa insulin lispro ndi zinthu zina

Amprenavir, betamethasone, hydrocortisone, hydrochlorothiazide, glucocorticosteroids, danazole, diazoxide, dexamethasone, isoniazid, nikotini acid, salbutamol, terbutaline, rhytodrin, mankhwala opatsirana kudzera pakamwa, mankhwala a antipyretic antipyretic. kufooketsa mphamvu ya insulin lyspro, n`zotheka kukula kwa hyperglycemia, kuchuluka kwa insulin lispro.
Acetylsalicylic acid, bisoprolol, sulfanilamide mankhwala, capopril, antidepressants (monoamine oxidase inhibitors), beta-blockers, octreotide, phenfluramine, enalapril, acarbose, anabolic steroids, tetracyclines, guanorotin ndegeitrogenitors, zoletsa za inhibitors. , mankhwala a ethanol ndi ethanol amalimbikitsa mphamvu ya insulin lispro.
Diclofenac amasintha mphamvu ya insulin lispro, kayendedwe ka shuga m'magazi ndikofunikira.
Mukagwiritsidwa ntchito limodzi ndi insulin, lyspro beta-blockers, clonidine, reserpine, bisoprolol imatha kubisala mawonetseredwe a zizindikiro za hypoglycemia.
Lyspro insulin sayenera kusakanikirana ndi nyama insulin yokonzekera.
Potsatira malangizo a dokotala, inshuwaransi ya Lyspro ingagwiritsidwe ntchito molumikizana ndi insulin yayitali yaumunthu kapena kukonzekera pakamwa sulfonylurea.
Mukamagwiritsa ntchito mankhwala ena ndi lyspro insulin, funsani dokotala.

Bongo

Ngati bongo wa insulin ndi lyspro, hypoglycemia imayamba: ulesi, njala, thukuta, kugwedeza, mutu, tachycardia, chizungulire, kusanza, kusawona bwino, chisokonezo, chikomokere, kufa.
Zolemba zofatsa za hypoglycemia zimayimitsidwa ndi kuyamwa kwa shuga, shuga, zinthu zomwe zimakhala ndi shuga (wodwalayo amalangizidwa kuti azikhala ndi shuga pafupifupi 20 g)
Kuwongolera kwa hypoglycemia moyenera kumatha kuchitika pogwiritsa ntchito subcutaneous kapena mu mnofu makonzedwe a glucagon ndikulowetsa chakudya chamthupi pambuyo pakukhazikika kwa mkhalidwe wa wodwalayo, dextrose (glucose) yothetsera imaperekedwa mwamphamvu kwa odwala omwe salabadira glucagon.
Ngati wodwala ali pachiwonetsero, ndiye kuti subcutaneous kapena intramuscular dongosolo la glucagon ndikofunikira, pakalibe glucagon kapena zochita pakayendetsedwe kake, yankho la dextrose liyenera kutumikiridwa mkati, pambuyo pobwezeretsa chikumbumtima, wodwalayo ayenera kupatsidwa chakudya chomwe chili ndi chakudya chamagulu ambiri, kuwunika wodwalayo komanso kudya zakudya zamagulu ambiri. kupewa kupewa kubwerezanso kwa hypoglycemia, ndikofunikira kudziwitsa dokotala za hypoglycemia wakale.

Kufotokozera za mankhwalawa

Mosiyana ndi ma insulin ena omwe amagwira ntchito mwachidule, Insulin Lizpro imayamba ndikuimitsa zotsatira zake mwachangu. Mphamvu yotere ya mankhwalawa imayamba chifukwa cha kuthamanga kwa mayamwa, chifukwa chake mutha kumwa nthawi yomweyo musanadye. Kuchuluka kwa mayamwidwe ndi kuyamba kwake kumakhudzidwa ndi malo omwe ali mthupi momwe jekeseniyo amathandizira. Mankhwalawa amakhala ndi mphamvu yokwanira theka la ola atatha kutsata, kwinaku akukwaniritsa izi kwa maola awiri. Mu thupi, mankhwalawa amakhala ndi pafupifupi maola anayi.

Mu kapangidwe kake, "Insulin Lizpro" imakhala ndi chinthu chofanana chomwe chimagwira, komanso zinthu zina zothandiza ndi madzi. Mankhwalawo pawokha ndi njira yowonekera yosawoneka bwino yomwe imaperekedwa kudzera mwaubwenzi. Mankhwala a Insulin Lizpro "amadzaza m'mabokosi a makatoni m'matumba kapena m'matumba apadera a syringe okhala ndi makatoni asanu a 3 ml a yankho.

"Insulin Lizpro" imalembedwa kuti:

• lembani matenda ashuga 1, ngati thupi sililekerera ma insulini ena,
• kuchuluka kwa shuga m'thupi, komwe sikukonzedwa ndi ma insulini ena,
• lembani matenda ashuga 2, ngati sizotheka kumwa mapiritsi kuti muchepetse shuga,
• kuthekera kwa kutengeka ndi minofu ya thupi ya ma insulini ena,
• opareshoni
• kukhalapo kwa matenda a shuga a mellitus

Mlingo wa mankhwala "Insulin Lizpro" ndi mankhwala. Amawerengeredwa potengera mulingo wamagazi anu. Mlingo wa tsiku ndi tsiku uyenera kuchuluka ngati wodwala ali ndi matenda opatsirana, kuchuluka kwa nkhawa, kuwonjezeka kwa chakudya chamagulu, komanso kusintha kwa mphamvu zolimbitsa thupi. Kulembera ndikotheka kuphatikiza ndi ma insulini ena.

Zolemba zaukadaulo wazachipatala

Kukonzekera kwa insulin ndikofunikira kwa odwala omwe ali ndi matenda amtundu wa 1 komanso kwa 40% ya odwala omwe ali ndi mtundu wachiwiri wa matenda.Insulin ndi mahomoni a polypeptide. Monga lamulo, mankhwalawa amaperekedwa mosavuta, koma pakachitika mwadzidzidzi, makonzedwe a intramuscular kapena intravenous amatha. Mlingo wake wa mayamwidwe mwachindunji umadalira malo a jakisoni, ntchito ya minofu, machitidwe a magazi ndi njira ya jakisoni.

Polumikizana ndi ma membroni am'mimba, maselo amayamba kupereka mphamvu zake pazamoyo:

• Kutsika kwamwazi wamagazi.
• Kachitidwe ka glycogen kaphatikizidwe.
• Kuponderezedwa kwa mapangidwe a matupi a ketone.
• Kuletsa mapangidwe a shuga kuchokera pazinthu zopanda mafuta.
• Kuseweretsa mapangidwe triglycerides ndi otsika kachulukidwe lipoproteins.
• Kuletsa kuchepa kwamafuta chifukwa cha kupangika kwamafuta acids kuchokera kumafuta.
• Imathandizira kupanga glycogen, yomwe imagwira ntchito ngati mphamvu yosungira thupi.

Kukonzekera kwa mankhwala a insulin kumawerengeredwa ndi komwe adachokera:

1. 1. Nyama (nkhumba) - Insulrap GPP, Ultralente, Ultralente MS, Monodar Ultralong, Monodar Long, Monodar K, Monosuinsulin.
2. 2. Umisiri (wopanga ndi kupanga majini) - Actrapid, Novorapid, Lantus, Humulin, Humalog, Novomiks, Protafan.
3. 3. Mapangizidwe opanga - Lizpro, Aspart, Glargin, Detemir.

Mankhwala amagawika potenga nthawi:

Ultrashort insulin

Wofinya msanga kuposa mitundu ina ya mankhwala. Imayamba kuchita mphindi 10-20 pambuyo pa kupangika, kuchititsa kuchepa kwa shuga m'magazi. Kuchuluka kwake kumachitika mkati mwa mphindi 30-180 ndipo kumatha maola 3-5.

Kusakaniza kwa magawo awiri a insulin yothamanga kwambiri komanso kuyimitsidwa kwa protamine kwa nthawi yayitali. Mankhwalawa ndi mtundu womwe umapangidwanso mu DNA ya munthu, zomwe zimasiyana pokhapokha potsatira proline ndi lysine amino acid zotsalira. Imayendetsa kagayidwe ka glucose ndipo imakhala ndi anabolic.

Zofanana ndi insulin yaumunthu. Kulowa minofu minofu imathandizira kusintha kwa glucose ndi amino acid kukhala mafuta. Zimatenga mphindi 15 pambuyo pa kutsata. Kuchuluka kwa mayamwa kumakuthandizani kuti mugwiritse ntchito mankhwalawa musanadye.

• Zisonyezero zogwiritsira ntchito: matenda a shuga a mtundu woyamba, kulekerera kwa mankhwala amtundu wina, postprandial hyperglycemia (sangathe kuwongolera), kuthamangitsa kuchepa kwa mahomoni a pancreatic. Matenda a 2 a shuga, kukana mankhwalawa a hypoglycemic, matenda omwe amagwirizana, othandizira opaleshoni.
• Njira yogwiritsira ntchito ndi Mlingo: zimatsimikiziridwa payekhapayekha kwa wodwala aliyense, kutengera mlingo wa glycemia m'magazi. Mankhwalawa amaperekedwa pokhapokha. Ngati ndi kotheka, imatha kuphatikizidwa ndi mankhwala a nthawi yayitali kapena sulfonylureas pakamwa.
• Kutsutsana kwa zigawo zikuluzikulu za mankhwala, insulinoma.
• Zotsatira zoyipa: thupi lawo siligwirizana, lipodystrophy, hypoglycemia, hypoglycemic chikomokere, kuyimitsidwa kwakanthawi.
• Kutopa kochulukirapo, kugona tulo ndi kupunduka, kutuluka thukuta, thukuta, tachycardia, njala, kupweteka pakamwa, mutu, kusanza ndi mseru, kusokonekera komanso kukhumudwa. Zowonongeka, kukhumudwa, chikomokere.

Chithandizo cha zovuta ndi mankhwala osokoneza bongo amakhala ndi subcutaneous, i / m kapena iv yoyendetsedwa ndi glucagon, iv makonzedwe a hypertonic dextrose solution. Ndi kukula kwa hypoglycemic chikomokere, mtsempha wamagetsi wamkati 40 ml ya dextrose 40% wa mankhwala umasonyezedwa mpaka wodwala atatuluka.

Analogue ya munthu mahomoni omwe ali ndi zochita za ultrashort. Kukonzekera kwake kunapezedwa ndi kuyambiranso kwa ukadaulo wa DNA pogwiritsa ntchito mtundu wa Saccharomyces cerevisiae. Ili ndi vuto la hypoglycemic. Imayamba kuchita mphindi 10-20 pambuyo povomerezeka pamakonzedwe ndikufika pazomwe zimachitika pochiritsa pambuyo pa maola 1-3.

Amagwiritsidwa ntchito pa matenda a shuga a mtundu woyamba ndi wachiwiri. Aspart imagwiritsidwa ntchito pokhazikitsa subcutaneous, mlingo umatsimikiziridwa ndi endocrinologist. Mankhwalawa ndiwotsutsana pokhapokha hypoglycemia ndi hypersensitivity zimapangidwira. Sichikugwiritsidwa ntchito pochiza odwala osakwana zaka 6, komanso pa nthawi yoyembekezera komanso mkaka wa m'mawere.

Pankhani ya mankhwala osokoneza bongo, pali zizindikiro za hypoglycemia, kupsinjika ndipo pamakhala chiwopsezo chokhala ndi vuto la hypoglycemic. Kuthana ndi hypoglycemia yofatsa ndikuchepetsa vutoli, ndikokwanira kumwa shuga kapena zakudya zomwe zili ndi zopatsa mphamvu zambiri zamagetsi. Nthawi zina, kuyambitsa njira ya 40% ya dextrose ndikofunikira.

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Yothetsera subcutaneous makonzedwe. Ndi analogue ya insulin yamunthu, yolingana ndi iyo mu mphamvu yakuchitapo. Zachulukitsa zochitika, koma nthawi yayifupi pochitapo kanthu poyerekeza ndi mahomoni amunthu.

• Amagwiritsidwa ntchito kulipiritsa chakudya chamafuta a m'mimba ndi kusowa kwa insulin. Kuvomerezedwa kuti mugwiritse ntchito pochiza ana azaka zopitilira 6. Imaperekedwa pang'onopang'ono kwa mphindi 15 musanadye kapena pambuyo chakudya. Mlingo ndi njira ya mankhwalawa imatsimikiziridwa ndi adotolo, aliyense payekha kwa wodwala aliyense.
• Hypersensitivity kwa glulisin kapena zigawo zina za mankhwala. Ndi chisamaliro chapadera chimagwiritsidwa ntchito kwa amayi apakati komanso odwala pakamayamwa.
• Zotsatira zoyipa: hypoglycemia ndi zovuta zina za metabolic, nseru ndi kusanza, kuchepa kwa chidwi, kuwonongeka kwa mawonekedwe, matupi awo sagwirizana ndi jakisoni. Nthawi zina, n`zotheka kukhala ndi khungu matenda, kumva zolimba pachifuwa, anaphylactic zimachitika.
• Mankhwala osokoneza bongo amawonetsedwa ndi zizindikiro za hypoglycemia wofatsa kapena wowopsa. Poyambirira, glucose kapena mankhwala okhala ndi shuga amasonyezedwa chithandizo. Mlandu wachiwiri, wodwalayo amapatsidwa kulowetsedwa kapena kutsekeka kwa shuga kapena dextrose.

Zochita zazifupi (insulin yosavuta yaumunthu) - achire zotsatira zimayamba mkati mwa mphindi 30-50 pambuyo pa kuperekedwa. Kuchuluka kwa zochitika kumatenga maola 1-4 ndipo kumatenga maola 5-8.

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Soluble Human genetic Engineering

Njira yothetsera jekeseni yomwe imaphatikizapo insulin yaumunthu, glycerol, metacresol ndi zinthu zina. Ili ndi kufupikitsa kwa hypoglycemic. Kulowa mthupi kumalumikizana ndi cholandilira chapadera cha maselo a cytoplasmic cell.

Imalimbikitsa mapangidwe a insulin receptor tata. Imayendetsa njira za intracellular, kapangidwe ka michere yofunika. Kukhazikika kwa mankhwala kumadziwika pambuyo pa mphindi 30 pambuyo pakukonzekera, ndipo kuchuluka kwake kumachitika mkati mwa maola 2-4, kutalika kwa maola ndi maola 6-8.

• Mawonekedwe 1 a shuga ndi osagwirizana-insulin-odziimira payokha matenda, matenda wamba, mikhalidwe zofuna kubwezeretsa kagayidwe kachakudya metabolism.
• Mlingo ndi makonzedwe: subcutanely, intramuscularly kapena kudzera m'mitsempha 30 asanadye chakudya chokhala ndi chakudya chamagulu ambiri. Mlingo watsiku ndi tsiku umachokera ku 0,5 mpaka 1 IU / kg kulemera kwa thupi.
• Hypersensitivity kwa zigawo zikuluzikulu za mankhwala, hypoglycemia, mimba ndi mkaka wa m`mawere.
• Zotsatira zoyipa: kutuluka thukuta ndi kukwiya, palpitations, kugunda kwa malekezero, njala, paresthesia mkamwa ndi zina chizindikiro cha hypoglycemic. Zomwe zimachitika m'deralo: kutupa pamalo a jakisoni, kuyabwa, lipodystrophy, matupi awo sagwirizana, kutupa.
• Mankhwala osokoneza bongo: amakhala ndi zofanana ndi zomwe zimachitika mosiyanasiyana. Ndi kukula kwa boma la hypoglycemic, zakudya zopatsa mphamvu zamafuta ambiri zimalimbikitsidwa, ndipo muzovuta, kukhazikitsidwa kwa njira ya dextrose kapena glucagon.

Biosulin imapezeka m'mabotolo a 10 ml iliyonse ndi makatiriji a 3 ml.

,

Mankhwala omwe amakwanira kuchepa kwa insulin ya insulin mu shuga mellitus. Ili ndi mitundu ingapo yomwe imasiyana mu gawo la yankho la insulin ndi protamine. Mtundu uliwonse umakhala ndi mankhwala ake, zomwe ndi magawo ake ogawa mthupi. Mitundu yonse imadziwika ndi kuyamba komanso nthawi yayitali yochitapo kanthu.

• Insuman Comb 15/85 - amagwira mphindi 30-55 pambuyo pa makonzedwe, achire kwambiri amatha pambuyo pa maola 3-5. Kutalika kwa kuchitapo kanthu ndi maola 11-20.
• Insuman Comb 25/75 - ikuyamba kuchita mphindi 30 mutatha kugwiritsa ntchito, mphamvu yayikulu imayamba pambuyo 1.5 maola, nthawi yochita ndi maola 12-18.
• Insuman Comb 50/50 - imagwira mphindi 30 pambuyo pa kutsika, kuchuluka kwake kumawonedwa pambuyo maola 1-1,5, nthawi yochita ndi maola 10-16.

Amagwiritsidwa ntchito pa mitundu ya matenda a shuga omwe amadalira insulin. Njira yothetsera vutoli imaperekedwa ola limodzi musanadye. Mlingo wakhazikitsidwa ndi adotolo.

Zotsatira zoyipa: khungu siligwirizana, lipodystrophy, insulin kukana, kwambiri aimpso kuwonongeka, hyperglycemic zimachitikira. Mankhwala osokoneza bongo ali ndi zofanana, koma zotchulidwa kwambiri. Hypersensitivity ku zigawo zikuluzikulu za mankhwala, matenda a shuga. Kupezeka mu mawonekedwe a kuyimitsidwa jekeseni Mbale 10 ml aliyense.

Mankhwala okhala ndi insulini wokhala ndi mawonekedwe okhala monocomponent komanso zochita zazifupi. Achire achire amakhala mphindi 30 pambuyo pa kukhazikitsa ndikufika pazokwanira mkati mwa maola 2-5. Achire zotsatira kumatenga kwa maola 6-8.

• Zisonyezero zosokoneza: matenda a shuga omwe amadalira insulin, chithandizo cha odwala omwe ali ndi vuto la mitundu inanso, opaleshoni yomwe ikubwera kwa odwala omwe ali ndi mtundu wachiwiri wa matenda a shuga, lipodystrophy.
• Njira yofunsira: ngati mankhwalawo akufotokozedwatu m'njira yoyenera, ndiye kuti amaperekedwa katatu patsiku, m'mitsempha kapena m'mitsempha. Mphindi 30 mutatha jakisoni, muyenera kudya chakudya. Mlingo watsimikiza ndi endocrinologist, payekhapayekha kwa wodwala aliyense.
• Zotsatira zoyipa: kuchepa kwambiri kwa shuga m'magazi, redness pamalo ophatikizira jakisoni ndi kuyabwa, khungu lawo siligwirizana.
• Mahomoni zotupa za kapamba, hypoglycemia. Gwiritsani ntchito panthawi yoyembekezera komanso mkaka wa m`mawere ndizotheka ndi mankhwala okha.

Actrapid NM imapezeka mu ampoules ya 10 ml yogwira ntchito iliyonse.

Brinsulrapi

Mankhwala osakhalitsa, akuwonetsa zochitika zake mphindi 30 pambuyo pakukonzekera kwamkati. Kwambiri achire zotsatira amapezeka mkati 1-3 maola ndipo kumatenga pafupifupi maola 8.

• Zizindikiro ntchito: 1 ndi 2 matenda ashuga mwa ana ndi akulu, kukana kwa m`kamwa hypoglycemic mankhwala.
• Njira yogwiritsira ntchito: Mlingo wa mahomoni wothandizidwa ndi mankhwalawa amatsimikiziridwa ndi dokotala, aliyense payekha kwa wodwala aliyense. Njira yothetsera vutoli imabayidwa mutangophatikiza syringe. Ngati mlingo wa tsiku ndi tsiku umaposa 0,6 U / kg, ndiye kuti mankhwalawo amagawidwa pawiri ndi jekeseni m'magawo osiyanasiyana a thupi.
• Zotsatira zoyipa: zotupa za pakhungu, angioedema, kugwedezeka kwa anaphylactic, lipodystrophy, cholakwika chosakhalitsa, minyewa yodutsitsa malo opangira jakisoni.
• Contrance: tsankho la munthu zigawo zikuluzikulu za mankhwala, hypoglycemic. Chithandizo pa mimba ndi mkaka wa m`mawere zimatheka pokhapokha pazachipatala. Amagwiritsidwa ntchito mosamala kwambiri pazochitika zolimbitsa thupi kapena zamaganizidwe.

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Humodar P100

Wofulumira wokhala munthu wopanga insulin. Imalumikizana ndi ma receptors a cytoplasmic cell membranes, ndikupanga insulini-receptor zovuta zomwe zimapangitsa njira zamkati mwake.

Matenda a shuga am'magazi amatengera kuwonjezeka kwa kutengeka kwakanthawi kwa timadzi timeneti, kuphatikiza bwino komanso kutsekeka kwa minofu. Mankhwala amayamba kuchita mphindi 30 pambuyo pa kupangika ndikufika pazowonjezera pambuyo pa maola 1-2, achire othandizira amakhalapo kwa maola 5-7.

• Zizindikiro zogwiritsidwa ntchito: matenda a shuga oyamba ndi oyambilira. Kukana pang'ono kapena kwathunthu kwa mankhwala amkamwa a hypoglycemic, matenda ashuga a ketoacidosis, matenda osokoneza bongo, kusokonezeka kwa kagayidwe kachakudya kosintha kwa insulin.
• Njira yoyendetsera ndi kumwa: mankhwalawa amapangidwira kuti azitha kutsata, kutsekeka ndi mtsempha wamitsempha. Mlingo wamba umachokera ku 0,5 mpaka 1 IU / kg kulemera kwa thupi. Timadzi timeneti timagwiritsidwa ntchito mphindi 30 chakudya chisanachitike. Yothetsera jekeseni ayenera kukhala kutentha. Ngati mankhwalawa amalembedwa monotherapy, ndiye kuti pafupipafupi makonzedwe ake ndi 3-5 patsiku.
• Contrance: tsankho lililonse pazigawo za mankhwala, zizindikiro za hypoglycemia. Kugwiritsa ntchito panthawi yoyembekezera kumaletsedwa, jakisoni panthawi yoyamwitsa imatheka pokhapokha pazamankhwala.
• Zotsatira zoyipa: khungu pakhungu, kuchuluka thukuta, kupweteka kwa m'mphepete, kukwiya, mseru komanso kusanza, kupweteka mutu. Thupi lawo siligwirizana pa jakisoni malo amatha.
• Hypoglycemic mkhalidwe wosiyanasiyana zovuta. Chithandizo chake chimakhala ndi kudya shuga kapena zakudya zopatsa mphamvu. Woopsa, kukhazikitsidwa kwa 40% yankho la dextrose kapena glucagon kumasonyezedwa.

Humodar P100 imatulutsidwa mu Mbale 10 ml komanso makatiriji 3 ml of solution iliyonse.

Berlinsulin N wabwinobwino U-40

Mankhwala ndi hypoglycemic kwenikweni. Amatengera mankhwala osokoneza bongo mwachangu komanso mwachidule. Kwambiri achire zotsatira zimachitika pambuyo maora 1-3 ndipo kumatha kwa maola 6-8.

Amagwiritsidwa ntchito pochiza mitundu yonse ya matenda ashuga komanso matenda ashuga. Mlingo umayikidwa payekha kwa wodwala aliyense. Monga lamulo, mankhwalawa amaperekedwa pang'onopang'ono kwa mphindi 10-15 musanadye katatu pa tsiku. Mlingo wa tsiku ndi tsiku ndi magawo 6-20. Kwa odwala omwe ali ndi hypersensitivity ku mankhwalawa, mlingo umachepetsedwa, ndikumverera kocheperako, zimachulukitsidwa.

Mankhwalawa amadziwikitsidwa chifukwa cha tsankho pamagawo ake ndi zizindikiro za hypoglycemia. Zizindikiro zoyipa zimawonetsedwa ndi kusintha kwa khungu lanu, kuwonongeka mu thanzi lonse.

Ma Insulin Yapakatikati

Pang'onopang'ono odzipereka ndipo ali ndi achire zotsatira 1-2 mawola jekeseni subcutaneous. Kuchuluka kwake kumatheka mkati mwa maola 4-12, kutalika kwa kuchitapo ndi maola 12-24.

Kuyimitsidwa kwa makina oyang'anira. Imayendetsa phosphatidylinositol dongosolo, zosintha shuga. Kuchulukitsa kulowa kwa potaziyamu. 1 ml ya kuyimitsidwa imakhala ndi 40 IU ya insulin yaumunthu ya biosynthet source. Amagwiritsidwa ntchito ngati matenda a shuga a shuga a shuga

Mankhwala amagwiritsidwa ntchito subcutaneous ndi mu mnofu makonzedwe. Mlingo ndi kuchuluka kwa jakisoni kumatsimikiziridwa ndi adotolo, aliyense payekha kwa wodwala aliyense. Isofan imaphatikizidwa mu hypoglycemic ndi chikomokere. Zotsatira zoyipa zimawonekera ndi kumverera kwanjala, kugwira ntchito mopitirira muyeso, kunjenjemera kwa malekezero, zovuta zina.

Monotard MS

Kukonzekera kwa insulin ndi nthawi yayitali. Muli 30% amorphous ndi 70% crystalline timadzi. Gawo lolimbikira ndi zinc kuyimitsidwa kwa monocomponent porcine insulin. Imayamba kugwira ntchito maola 2,5 pambuyo pa utsogoleri, zotsatira zake zimakhala pambuyo pa maola 7 mpaka 15 ndipo zimapitilira tsiku limodzi.

• Zisonyezero zamtundu uliwonse: shuga
• Njira yogwiritsira ntchito: mlingo umasankhidwa ndi dokotala payekhapayekha kwa wodwala aliyense. Mankhwalawa amalowetsedwa mozama pang'ono, nthawi iliyonse akusintha jakisoni. Ngati mulingo uposa 0,6 U / kg, ndiye kuti uzigawidwa pawiri m'malo osiyanasiyana. Odwala omwe amalandila mankhwala opitilira 100 pa mankhwala patsiku, amagonekedwa kuchipatala.
• Zotsatira zoyipa za hypoglycemic zosiyanasiyana. Hyperemia pamalo jakisoni, khungu lawo siligwirizana.
• Hypoglycemic zinthu ndi hypoglycemic chikomokere.

Monotard MS ikupezeka mu mawonekedwe a kuyimitsidwa kwa jakisoni mu mamililita 10.

Insulong SPP

Hypoglycemic wothandizira wa nthawi yayitali. Amagwiritsidwa ntchito pochiza mitundu ya shuga 1 ndi 2. Mankhwalawa amagwiritsidwa ntchito popangira jakisoni wotsekemera mu ntchafu; amathandizidwanso kuperekera mankhwalawo kukhoma lakumbuyo yam'mimba, matako, ndi minyewa yamafupa. Mlingo amawerengedwa ndi endocrinologist, kuyang'ana kuchuluka kwa shuga m'magazi a wodwala ndi zina za thupi lake.

Mankhwala ndi contraindicated vuto la hypersensitivity ake zigawo zikuluzikulu, hypoglycemia. Zotsatira zoyipa zimawonetsedwa ndikuphwanya kutulutsa komanso kutupira miyendo. Ngati vuto la kuperewera kwa vuto la kuperewera kwa zakudya m'thupi mumagwiritsidwa ntchito kapena mugwiritsa ntchito mlingo waukulu, hypoglycemia imayamba. Zothekanso zotheka zakomweko pambuyo pa jakisoni: redness, kutupa ndi kuyabwa.

Kuchita insulini kwa nthawi yayitali

Zimachitika pakadutsa maola 1-6 pambuyo pa utsogoleri. Mofananako amachepetsa shuga. Ili ndi chiwonetsero chambiri chosadziwika ndipo imagwira ntchito kwa maola 24. Amakulolani kuti mupange jakisoni 1 nthawi patsiku.

Kukonzekera kwa insulin ndi hypoglycemic kukonzekera ndi chophatikiza ndi glargine (analogue of the human hormone). Imakhala ndi madzi ochepa osaloŵerera m'ndale. Mothandizidwa ndi subcutaneally, asidiyo samatalikirana ndipo amapanga microprecipitate, natulutsa insulin.

• Zisonyezero zogwiritsira ntchito: mawonekedwe a shuga omwe amadalira odwala ndi ana opitirira zaka 6.
• Njira yogwiritsira ntchito: Kuchitapo kanthu kwa nthawi yayitali kumayambira pakukhazikitsidwa kwa gawo lophatikizika mu mafuta ochepa. Mphamvu imeneyi imakuthandizani kuti muzigwiritsa ntchito kamodzi patsiku. Mlingo amawerengedwa kwa wodwala aliyense payekhapayekha.
• Zotsatira zoyipa: kagayidwe kazakudya kosiyanasiyana kosiyanasiyana. Nthawi zambiri, pamakhala kuchepa kwa maonekedwe acuity, lipoatrophy, lipohypertrophy, dysgeusia, thupi lawo siligwirizana. Nthawi zina, kuwopsa kwa anaphylactic, myalgia, bronchospasm kumachitika.
• Hypersensitivity kwa mankhwala, hypoglycemia, matenda ashuga ketoacidosis. Mankhwala ali osavomerezeka zochizira amayi apakati ndi ana.
• Kusagwirizana ndi kumwa kumawopseza kukula kwa mitundu yayitali ya hypoglycemia, yomwe imakhala yowopsa kwa wodwalayo. Zizindikiro zofooka zimalepheretsa kudya zamafuta ambiri. Woopsa milandu, mtsempha wa magazi a shuga wokhazikika amasonyezedwa.

Lantus ikupezeka mu mawonekedwe a yankho la jakisoni, mu 3 ml cartridgeges.

Levemir Penfill

Antidiabetesic wothandizira, analogue ya basal ya anthu yokhala ndi nthawi yayitali. Kutalika kwazitali kumachitika chifukwa cha kuyanjana kwa mamolekyu azinthu zomwe zimagwira ntchito ndi albin kudzera m'matcheni a mafuta achilengedwe pamalo opangira jekeseni. Zotsatira za hypoglycemic zimapitilira kwa maola 24, koma zimatha kukhala zosiyanasiyana kutengera mlingo. Kuchitapo kanthu kwa nthawi yayitali kumalola kugwiritsa ntchito mankhwalawa 1-2 patsiku.

• Amagwiritsidwa ntchito pochiza matenda a shuga a mtundu woyamba. Njira yothetsera vutoli imathandizidwa pang'onopang'ono, mlingo umasankhidwa payekhapayekha kwa wodwala aliyense, kutengera zosowa za thupi lake komanso mawonekedwe a matendawa.
• Zotsatira zoyipa: kupweteka kuposa khungu, kunjenjemera kwa malekezero, kuchuluka kwa mantha, nkhawa, kugona, kuthamanga kwa mtima, kusokonezeka poyang'ana ndi masomphenya, paresthesia. Zomwe zimachitika mderalo momwe minofu imakhudzira, kuyabwa, lipodystrophy ndi hyperemia ya khungu ndizothekanso. Mankhwala osokoneza bongo ali ndi zofanana. Chithandizo chimakhala pakudya zakudya zopatsa mphamvu.
• Contrance: tsankho kwa magawo a mankhwalawa. Gwiritsani ntchito panthawi yomwe muli ndi pakati komanso mkaka wa m`mawere zimatheka pokhapokha pazamankhwala ndikuyang'aniridwa ndi endocrinologist.

Levemir Penfill imapezeka mu 3 ml cartridgeges (mayunitsi 300) mwanjira yothetsera makolo.

Tresiba FlexTouch

Chiwonetsero cha mahomoni amunthu wakuchita mopitilira muyeso. Limagwirira a zochita za mankhwala zachokera mogwirizana ndi zolandirana anthu amkati insulin. Mphamvu ya hypoglycemic imayamba chifukwa cha kugwiritsidwa ntchito kwakukulu kwa glucose ndi minyewa pambuyo poti timadzi timene timalumikizana ndi maselo a mafuta ndi minofu.

• Mankhwalawa amagwiritsidwa ntchito pochiza matenda ashuga mwa akulu ndi achinyamata, komanso ana okulirapo chaka chimodzi. Njira yothetsera vutoli imagwiritsidwa ntchito pothandizidwa ndi subcutaneous, muyezo umawerengeredwa ndi adokotala, aliyense payekha kwa wodwala aliyense.
• Tsankho kwa zigawo zikuluzikulu za mankhwala, pakati ndi mkaka wa m`mawere.
• Zotsatira zoyipa: hypoglycemia, matupi awo sagwirizana ndi jakisoni malo, lipodystrophy. Matenda a chitetezo chamthupi, zotumphukira edema, komanso kukhudzika ndizothekanso. Mankhwala osokoneza bongo ali ndi zofanana. Kuti muthane ndi zowawa, ndikulimbikitsidwa kuti mutenge mankhwala okhala ndi shuga mkati. Ngati hypoglycemia ili yoopsa, kukhazikitsa njira ya dextrose ndikofunikira.

Tresiba FlexTouch imapezeka mu ma syringes a subcutaneous jakisoni wa 100 ndi 200 mayunitsi / ml.

Kuphatikiza pamagulu omwe ali pamwambawa a mankhwalawa, palinso zosakanikirana zama insulin zamitundumitundu yosiyanasiyana ya zochita: aspart magawo awiri NovoMix 30/50, FlexPen, Penfill, Lizpro, magawo awiri a Humalog Remix 25/50.

Zizindikiro ndi malangizo ogwiritsa ntchito

Insulin Lizpro imagwiritsidwa ntchito pochiza odwala matenda a shuga, ngakhale atakhala kuti ndi amuna kapena akazi komanso zaka. Chipangizocho chimakhala ndi zizindikiro zapamwamba kwambiri ngati wodwala amakhala ndi moyo wopanda vuto, makamaka kwa ana.

Humalog imayikidwa ndi dokotala wokhazikika ndi:

1. Lembani 1 ndi 2 mtundu wa mellitus wa shuga - pamapeto pake, kokha ngati kumwa mankhwala ena sikumabweretsa zotsatira zabwino,
2. Hyperglycemia, yomwe siyimalimbikitsidwa ndi mankhwala ena.
3. Kukonzekera wodwalayo kuti achite opareshoni,
4. Kusagwirizana ndi mankhwala ena okhala ndi insulin,
5. The kupezeka kwa matenda zinthu zikusokoneza njira ya matenda.

Njira yogwiritsira ntchito mankhwalawa yovomerezeka ndi wopanga ndi yopanda tanthauzo, koma malinga ndi momwe wodwalayo alili, wothandiziridwayo amatha kuthandizidwa kudzera mu mnofu komanso m'mitsempha. Ndi njira yodutsa, malo abwino kwambiri ndi m'chiuno, phewa, matako ndi m'mimba.

Kukhazikika kwa makulidwe a Insulin Lizpro nthawi yomweyo amatsutsana, chifukwa izi zingapangitse kuwonongeka kwa khungu pakhungu.

Gawo lomweli silingagwiritsidwe ntchito kuperekera mankhwala oposa 1 mwezi pamwezi. Ndi subcutaneous makonzedwe, mankhwalawa angagwiritsidwe ntchito popanda kupezeka kwa akatswiri azachipatala, koma pokhapokha ngati dotolo linasankhidwa ndi katswiri.

Nthawi ya kukhazikitsidwa kwa mankhwalawa imapangidwanso ndi dokotala, ndipo iyenera kuonedwa mosamala - izi zimathandiza kuti thupi lizolowerana ndi boma, komanso liperekenso mphamvu yautali wa mankhwala.

Kusintha kwa Mlingo kufunikira pa:

• Kusintha zakudya ndikusinthira ku chakudya chochepa kapena chamtundu wazakudya zambiri,
• Kupsinjika mtima
• Matenda opatsirana
• Kugwiritsa ntchito mankhwala ena
• Kusintha kuchokera ku mankhwala ena omwe amagwira ntchito mwachangu omwe amakhudza kuchuluka kwa glucose,
• Kuwonetsera kulephera kwa impso,
• Mimba - kutengera ndi trimester, kufunikira kwa thupi pakusintha kwa insulin, motero ndikofunikira
• Pitani kwa omwe amakupatsani chithandizo chazaumoyo pafupipafupi ndikuyeza kuchuluka kwa shuga.

Kusintha pamalingaliro kungafunikenso pakusintha wopanga Insulin Lizpro ndikusintha pakati pa makampani osiyanasiyana, popeza aliyense wa iwo amasintha momwe amapangidwira, zomwe zingakhudze kugwiriridwa kwa mankhwalawo.

Zotsatira zoyipa ndi contraindication

Posankha mankhwala, dokotala wopezekapo amayenera kuganizira zonse zomwe zimachitika m'thupi la wodwalayo.

Insulin Lizpro imaphatikizidwa mwa anthu:

1. Ndi chidwi chochulukirapo pazinthu zazikulu kapena zowonjezera,
2. Ndi kuchuluka kwambiri kwa hypoglycemia,
3. Momwe mumakhala insulinoma.

Pogwiritsa ntchito mankhwalawa odwala matenda ashuga, zotsatirazi zoyipa zimawonedwa:

1. Hypoglycemia - ndiyoopsa kwambiri, imachitika chifukwa cha mlingo wosankhidwa mosamala, komanso ndimankhwala omwe amadzipangira nokha, imatha kubweretsa imfa kapena kusokonezeka kwakukulu kwa zochitika zaubongo,
2. Lipodystrophy - imachitika chifukwa cha jakisoni m'dera lomwelo, kupewa, ndikofunikira kusintha magawo a khungu,
3. Chiwopsezo - chimawonekera kutengera mawonekedwe a thupi la wodwalayo, kuyambira pakuwonjezeranso kuperewera kwa jakisoni, ndikutha ndi kuwonongeka kwa anaphylactic,
4. Zowonongeka za zida zowonera - ndi mlingo wolakwika kapena kusalolera payekhapayekha ziwalo zina, retinopathy (kuwonongeka kwa kufinya kwa diso chifukwa cha kusokonezeka kwa mitsempha) kapena kuwonongeka kwamawonekedwe pang'ono kumachepera, nthawi zambiri kumadziwonekera mudakali ana kapena kuwonongeka kwa mtima,
5. Zomwe zimachitika mdera lanu - m'malo a jakisoni, redness, kuyabwa, redness ndi kutupa zimatha, zomwe zimadutsa thupi litazolowera.

Zizindikiro zina zimatha kuonekera patapita nthawi yayitali. Ngati muli ndi mavuto, siyani kumwa insulini ndikuwonana ndi dokotala. Mavuto ambiri nthawi zambiri amathetsedwa ndikusintha kwa mlingo.

Kuchita ndi mankhwala ena

Popereka mankhwala a Humalog, dokotala wopezekapo ayenera kuganizira zomwe mukumwa kumwa kale. Zina mwa izo zimatha kuwonjezera ndi kuchepetsa zochita za insulin.

Zotsatira za Insulin Lizpro zimatheka ngati wodwala atenga mankhwala ndi magulu otsatirawa:

• Mao zoletsa,
• Sulfonamides,
• Ketoconazole,
• Sulfonamides.

Ndi kugwiritsanso ntchito mankhwalawa mankhwalawa, ndikofunikira kuchepetsa mlingo wa insulin, ndipo wodwala ayenera, ngati nkotheka, akane kumwa nawo.

Zinthu zotsatirazi zimachepetsa mphamvu ya Insulin Lizpro:

• Njira za kulera
• Ma estrogens
• Glucagon,
• Nikotini.

Mlingo wa insulin pamenepa uyenera kuchuluka, koma ngati wodwalayo akana kugwiritsa ntchito zinthu izi, mpofunika kusintha kwachiwiri.

M'pofunikanso kuganizira zina mwazakudya ndi Insulin Lizpro:

1. Pakuwerengera kuchuluka kwake, dokotala ayenera kuganizira kuchuluka ndi chakudya chomwe odwala amadya,
2. Mu matenda a chiwindi ndi impso, mlingo umayenera kuchepetsedwa.
3. Humalog imatha kuchepetsa ntchito ya kayendedwe ka mitsempha, zomwe zimakhudza kuchuluka kwa zomwe zimachitika, ndipo izi zimabweretsa ngozi, mwachitsanzo, kwa eni magalimoto. Analogs of the insulin Lizpro

Insulin Lizpro (Humalog) imakhala ndi mtengo wokwera kwambiri, chifukwa chomwe odwala nthawi zambiri amapita kukafuna ma analogues.

Mankhwala otsatirawa akhoza kupezeka pamsika omwe ali ndi mfundo zomwezi:

• Monotard
• Protafan
• Rinsulin
• Pakati
• Khalid.

Ndi zoletsedwa kuti asankhe mankhwalawo m'malo mwake. Choyamba muyenera kulandira upangiri kuchokera kwa dokotala, chifukwa kudzipanga nokha kungayambitse imfa.

Ngati mukukayikira luso lanu lazinthu, chenjezo katswiri za izi. Kapangidwe kamankhwala aliwonse kumasiyanasiyana malinga ndi omwe akupanga, chifukwa cha momwe mphamvu yamomwe mankhwalawo amachitikira m'thupi la wodwalayo imasintha.

Mankhwalawa amagwiritsidwa ntchito nthawi zambiri mitundu yosagwiritsa ntchito insulin (1 ndi 2), komanso chithandizo cha ana ndi amayi apakati. Kuwerengera kolondola kwa mankhwalawa, Humalog sikubweretsa mavuto komanso amakhudza thupi pang'ono.

Mankhwalawa amatha kutumikiridwa m'njira zingapo, koma zofala kwambiri ndizopanga, ndipo opanga ena amapereka chida chija ndi jakisoni wapadera yemwe munthu angagwiritse ntchito osakhazikika.

Ngati ndi kotheka, wodwala yemwe ali ndi matenda ashuga amatha kupeza maupikisano mu malo ogulitsa mankhwala, koma popanda kufunsana ndi katswiri, kugwiritsa ntchito kwawo nkoletsedwa. Insulin Lizpro imagwiritsidwa ntchito ndi mankhwala ena, koma nthawi zina kusintha kwakofunikira kwa mankhwalawa kumafunikira.

Kugwiritsa ntchito mankhwalawa pafupipafupi sikungosokoneza, koma wodwalayo ayenera kutsatira njira yapadera yomwe ingathandize thupi kuti lizolowera zinthu zina.

Momwe mungatenge INSULIN LIZPRO

Jakisoni amachitidwa pansi pa khungu pamimba, phewa, ntchafu kapena matako. Ndikofunikira kusinthana mawebusayiti a jakisoni kuti musabare jekeseni malo amodzi kamodzi pamwezi. Chisamaliro chiyenera kuthandizidwa popereka jakisoni kuti muwononge mitsempha ya magazi. Ndi zoletsedwa kumwa mankhwalawo mwanjira ina iliyonse kupatula jekeseni.

Contraindication

Mankhwala "Insulin Lizpro" ali ndi zotsutsana pakugwiritsa ntchito kwake:

• kusalolera kwa chinthu chogwira ntchito,
• kukhalapo kwa chotupa mu kapamba,
• shuga wamagazi ochepa

Pamaso pakulephera kwa hepatic kapena aimpso, mankhwalawa saloledwa kugwiritsidwa ntchito, koma kuchuluka kwake kuyenera kuyendetsedwa nthawi zonse.

Zotsatira zoyipa

Kugwiritsa ntchito mankhwala a Insulin Lizpro, wodwalayo ayenera kukonzekera mawonekedwe a mavuto ena, owoneka ngati ziwopsezo, kutentha thupi pang'ono, kuchepa kwa mawonekedwe, kuchepa kwa magazi m'magazi, komanso kunenepa kwambiri. Mankhwala osokoneza bongo amachititsa kuti madontho azisokonekera, kugona, kusowa tulo, kupweteka mutu, kusawona bwino, kukokana komanso kutsitsekeka.