Momwe mungagwiritsire ntchito Augmentin EU Powder

Palibe amene amadwala matenda opatsirana. Zamoyo zosalimba za ana zimakhala pachiwopsezo chachikulu. Kuthandiza ana kuyambira zaka 3, madokotala nthawi zambiri amamulembera Augmentin EU. Ndi mankhwala amphamvu omwe amatenga mawonekedwe a kuyimitsidwa. Kuti ana azitha kumwa mankhwalawo mosangalala, wopangawo anapatsa kukoma kwawo kwa mabulosi.

Zambiri pazamankhwala

"Augmentin EC" ndi ufa womwe kuyimitsidwa kwake kumakonzekera kukonzekera pakamwa. Mankhwalawa amadzaza m'mabotolo, zomwe zimakhala zokwanira kukonzekera 100 ml ya mankhwalawa. Mlingo wa chinthu yogwira (amoxicillin) ndi 600 mg. Monga chinthu chothandizira, clavulanic acid wambiri ya 42.9 mg, silicon dioxide, sodium carboxide, asparcum, xanthan chingamu, komanso kununkhira kwa sitiroberi, zomwe zimathandizira kugwiritsa ntchito mankhwalawa kwa ana aang'ono, amachita.

Katundu woyambira

Augmentin EU ndi anti-wodziwikiratu maantibayotiki omwe ali opanga pang'ono. Amoxicillin amawonetsa ntchito yolimbana ndi tizilombo toyambitsa matenda ambiri. Komabe, imakhudzidwa ndi beta-lactamase ndipo imawonongedwa ndi kukopa kwake. Chifukwa chake, amoxicillin satha kugwira ntchito polimbana ndi tizilombo tomwe timatulutsa timadzi tambiri.

Clavulanic acid imadziwika ndi mtundu womwe umafanana ndi penicillin. Izi zimabweretsa ntchito yotchulidwa motsutsana ndi beta-lactamases, yomwe nthawi zambiri imayambitsa kukula kwa antibayotiki. Chifukwa chake, kupezeka kwa asidi mu kapangidwe ka mankhwala "Augmentin EU" kumateteza gawo lalikulu kuti lisawonongedwe motsogozedwa ndi michere yambiri ndikukulitsa mawonekedwe ake a antibacterial. Chifukwa chake, ngakhale mabakiteriya omwe nthawi zambiri amalimbana ndi amoxicillin amafa mothandizidwa ndi mankhwalawa.

Titha kunena kuti Augmentin EC (kuyimitsidwa) sikuwonetsa katundu wokhala ndi antiotic, komanso beta-lactamase inhibitor. Ma bactericidal omwe ali ndi tizilombo tosiyanasiyana tambiri timapangitsa kuti mankhwalawa akhale othandiza. Ndizofunikira kudziwa kuti onse amoxicillin ndi clavulanic acid amadziwika ndi gawo lotsika kwambiri lomanga kumaproteni amwazi. Chifukwa chake, zoposa 70% yazomwe zimagwiritsidwabe ntchito zimangokhala m'madzi osasinthika.

Zizindikiro zazikulu

Madokotala adatha kuyesa kuyeserera kwa mankhwala monga Augmentin EU (kuyimitsidwa). Amawalembera odwala omwe apezeka ndi mavuto otsatirawa:

• mabakiteriya omwe amapezeka pakumapazi kwapamwamba, komanso makutu, mphuno ndi mmero (ma kachilengedwe sayenera kukana magwiridwe antchito a antibayotiki omwe amafunsidwa),
• olimbikira kapena obwereza otitis media (monga lamulo, mankhwalawa amaperekedwa kwa ana ngati othandizira ena a antibacterial sanachite bwino,
• sinusitis ndi tonsillopharyngitis,
• lebar, bronchopneumonic ndi matenda ena am'munsi kupuma kwamatumbo,
• matenda a pakhungu, komanso njira yotupa m'matumba ofewa.

Contraindication

Tsoka ilo, si aliyense amene angamwe mankhwala monga Augmentin EC (kuyimitsidwa kwa ana). Malangizowa ali ndi chidziwitso chotsutsana ndi zotsutsana zazikuluzikulu izi:

• Hypersensitivity yogwira zigawo zikuluzikulu za mankhwala, omwe amatha kupezeka ndi ma labotale
• kupezeka kwa khothi,
• hepatic dysfunction, yomwe idayambitsidwa ndi kulandiridwa kwa "Augmentin" m'mbuyomu.

Mankhwala "Augmentin EU": malangizo a ana

Kuti mankhwalawa akhale ndi mphamvu yofunikira m'thupi, ndikofunika kuigwiritsa ntchito moyenera, ndikuwonetsetsa dongosolo ndi kuchuluka kwake. Augmentin EC (kuyimitsidwa kwa ana) nthawi zambiri amatengedwa asanadutse masiku 10. Pankhaniyi, mankhwalawa amayenera kumwedwa kawiri pa tsiku, ndi maola 12.

Ndikofunika kudziwa kuti mankhwalawa ndi ovomerezeka kupatsa ana okalamba kuposa miyezi itatu. Komanso, maphunziro azachipatala atsimikizira kutha kwa mankhwalawa mankhwalawa odwala omwe thupi lawo silinapitirire 36 kg. Kwa ana olemera kuposa makilogalamu 40, komanso akulu, zoyesa sizinachitike, chifukwa chake ndizosatheka kuyankhula za kuyenera kwake.

Kutengera ndi kulemera kwa thupi la mwana, kuchuluka kwa amadyedwa Augmentin EC-600 amatsimikiza (kuyimitsidwa kwa ana). Mlingo uli motere:

Ndikofunika kudziwa kuti mulingo woyenera wa mankhwalawo ndi wokhawo womwe ukufunsidwa. Augmentin EC (kuyimitsidwa kwa ana) amadziwika ndi gawo lapadera lazinthu zogwira ntchito komanso zothandizira zomwe sizinthu zamtundu wina uliwonse wa Augmentin.

Momwe mungachepetse zoyipa pamimba?

Antibiotic Augmentin EU-600, monga mankhwala ena aliwonse, ali ndi vuto pamimba komanso kugaya chakudya mokwanira. Kuti muchepetse kuvulaza kumeneku, tikulimbikitsidwa kutenga kuyimitsidwa nthawi yakudya (makamaka kumayambiriro kwa chakudya). Njira yogwiritsira ntchito imeneyi sikuti imangoteteza makhoma am'mimba, komanso zimathandizira kuti kuyamwa kwabwino kwa zinthu zogwira ntchito.

Kodi kuyimitsidwa kwakonzedwa bwanji?

Mwanthawi ya ufa, womwe umapezeka mu botolo laling'ono, umalowa mu gulu lachipatala la Augmentin EU-600. Kusandutsa ufa kukhala potoni wochiritsa sikuvuta konse. Kuyimitsidwa kwa ana kwakonzedwa motere:

1. Mu botolo lokhala ndi ufa wokhala ndi 100 ml muyenera kuwonjezera 90 ml ya madzi (muyenera kuchita izi m'njira ziwiri).
2. Choyamba muyenera kulowa pafupi 2/3 ya buku lathunthu lamadzimadzi, kotero kuti ufa umaphimbidwa ndi madzi.
3. Botolo liyenera kutsekedwa ndi chipewa ndikugwedezedwa bwino kuti libwerere mumtengowo.
4. Onjezerani kuchuluka kwa madzi onse omwe amafunikira (tcherani khutu ku botolo) ndikugwedezanso bwino.
5. Siyani vial yodzazidwa ndi kuyimitsidwa kuti mupumule kwa mphindi 5, kuti zigawo zonse za mankhwalazo zimalumikizane (ndondomeko yobalalitsa).
6. Ngati mudachita chilichonse moyenera, muyenera kupeza madzi oyera omwe amakhala ndi imvi.

Zotsatira zoyipa

Monga mankhwala ena aliwonse, amatsogolera ku zovuta zina za Augmentin EC-600 (kuyimitsidwa kwa ana). Bukuli lili ndi zidziwitso zamavuto otsatirawa:

Kusintha leukopenia kapena neutropenia, hemolytic magazi, agranulocytosis, thrombocytopenia, kuchuluka magazi nthawi.

Ndikofunika kudziwa kuti mavuto ambiri amachitika pambuyo pa kutha kwa kumwa mankhwala a Augmentin EU-600. Malangizo ogwiritsira ntchito ali ndi chidziwitso chomwe mawonetsedwe oyamba amatha kuchitika ngakhale patatha milungu ingapo atachotsedwa.

Bongo

Ndikofunikira kutsatira mosamalitsa malangizo m'mene mumamwa mankhwalawa "Augmentin EU" (kuyimitsidwa). Mlingo wa ana uyenera kuyang'aniridwa mosamala kuti apewe mavuto. Mwana akamamwa mankhwala ambiri kuposa momwe amafunidwira, akhoza kukhala kuti ali ndi vuto la m'mimba, komanso madzi am'madzi. Pankhaniyi, muyenera kusiya kumwa mankhwalawo ndikupita kukalandira chithandizo, mosamala kwambiri pobwezeretsa madzi. Nthawi zina, mankhwala osokoneza bongo amakumana ndi crystalluria. Kenako dokotalayo angaganize za kugwiritsa ntchito hemodialysis pochotsa mankhwalawo m'magazi.

Zokhudza kugwiritsa ntchito mankhwalawa

Madokotala pachipatala cha ana omwe ali ndi anti Augmentin EU ali ndi zokumana nazo zambiri. Malangizowa ali ndi zambiri zothandiza zokhudzana ndi kapangidwe kake ka mankhwala. Komabe, potengera mtundu wankhanza kwambiri, titha kufotokoza zina mwazomwe zimagwirizana ndi njira yochizira. Chifukwa chake, tikulankhula motere:

• Musanayambe kumwa mankhwalawa, muyenera kukayezetsa kuchipatala kuti mupeze zovuta zilizonse kapena kusalolera kwanu pazinthu zilizonse za mankhwalawo.
• Ngati m'mbuyomu wodwalayo adakumana ndi vuto la penicillin, ndiye kuti Augmentin sayenera kugwiritsidwa ntchito. Izi zimatha kubweretsa hypersensitivity, yomwe nthawi zambiri imabweretsa imfa.
• Ngati thupi lanu siligwirizana, phwando la "Augmentin" liyenera kuyimitsidwa nthawi yomweyo. Izi zikuyenera kutsatiridwa ndi kuchezera kwa dokotala yemwe adzakupatseni chithandizo chamankhwala ndi njira zina zochiritsira.
• Ngati anaphylactic zimachitika, chithandizo chodzidzimutsa ndi adrenaline nthawi zambiri chimafunika. Kuphatikiza apo, chithandizo cha okosijeni chitha kuperekedwa, komanso intravenous steroid management ndi intubation kuti kukhalabe ndi kupuma ntchito.
• Ngati matenda a mononucleosis akukayikiridwa, chithandizo ndi Augmentin chimatsutsana kwambiri. Kupanda kutero, pali kuthekera kwakukulu kwa chotupa chomwe chimawoneka ngati chikuku.
• Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumatha kupangitsa kuti tizilombo tating'onoting'ono tokhala tulo tosavutikira ku Augmentin EU.
• Mwambiri, mankhwalawa amalekeredwa bwino ndi odwala, chifukwa ali ndi zizindikiro zochepa za poizoni. Komabe, pogwiritsa ntchito nthawi yayitali, kuwunika kawirikawiri chiwindi ndi impso ndikofunikira.
• Nthawi zina, mavuto okhala ndi magazi komanso magazi amayambika. Chisamaliro chofunikira chimafunikira mkhalidwe wa wodwalayo mukamamwa mankhwala opatsirana pamodzi.
• Kwa odwala omwe ali ndi vuto la chiwindi, Augmentin EC iyenera kumwedwa mosamala kwambiri komanso kuyang'aniridwa ndi dokotala nthawi zonse.
• Odwala omwe ali ndi vuto la impso, mlingo wake uyenera kusinthidwa malinga ndi kukhala bwino ndi chizindikiro cha matenda.
• Mukamagwiritsa ntchito mankhwala odwala omwe amachepetsa mkodzo katulutsidwe, crystalluria ingachitike. Kuti muchepetse kuwoneka kwa mawonekedwe oterowo, ndikofunikira kuwunika pafupipafupi kuchuluka kwamadzimadzi amkati ndi mkodzo womwe umatuluka m'thupi.
• Popeza kuti asparkum ndi gawo lamankhwala omwe amafunsidwa, ayenera kugwiritsidwa ntchito mosamala odwala omwe apezeka ndi phenylketonuria.
• Mukufufuza ndi kuyesa kwa labotale, palibe zoyipa zilizonse pakuwoneka kwa odwala kuyendetsa magalimoto ndi njira zina. Mwakutero, chizindikirochi sichingaganiziridwe kukhala chachikulu, chifukwa kuyimitsidwa kumayikidwa makamaka kwa ana.

Kuyanjana kwa mankhwala osokoneza bongo

Kwa odwala omwe akutenga Augmentin EU, malangizo ogwiritsira ntchito amakhazikitsa zoletsa zina pa nthawi yomweyo kugwiritsa ntchito mankhwala ena. Chifukwa chake, kugwiritsa ntchito kwa "Probenecid", komwe kumachepetsa kubisala kwa aimpso sikulimbikitsidwa. Kugwiritsira ntchito nthawi yayitali kungayambitse kuchuluka kwa amoxicillin m'magazi, koma sizikhudzanso kuchuluka kwa clavulanic acid.

Kugwiritsa ntchito nthawi yomweyo "Allopurinol" kumapangitsa kuti chiwopsezo chizigwirizana (makamaka khungu). Palibenso kafukufuku wina wokhudza nkhaniyi amene anachitapo. Komanso, kupita kwa asing'anga kumayenera kuchenjeza odwala awo kuti Augmentin, monga mankhwala ena aliwonse, amachepetsa mphamvu ya njira zolerera zam'kamwa. Koma pazida zomwe zafotokozedwa m'nkhaniyi, kudziwa kumeneku sikofunika kwenikweni.

Kulandila pa mimba ndi mkaka wa m`mawere

Kafukufuku wazinyama sanawonetse vuto lililonse. Chifukwa chake chiopsezo cha kusokonezeka kwa chiberekero cha mwana wosabadwayo mutatenga Augmentin sichikula (poyerekeza ndi maantibayotiki ena). Ponena za kugwiritsa ntchito mankhwalawa kwa amayi apakati, pali chiopsezo chowonjezeka cha ana obadwa kumene. Chifukwa chake, munthawi ya bere, ndibwino kukana kugwiritsa ntchito mankhwalawa, pokhapokha ngati phindu lomwe likuyembekezeredwa silipitilira chiopsezo.

Pofotokoza za nthawi ya mkaka wa m'mawere, ndikofunikira kudziwa kuti zigawo zikuluzikulu za mankhwalawa zimapukusidwa mkaka wa m'mawere. Palibe umboni wonena za zoyipa za zinthu izi pa mwana wakhanda woyamwa. Komabe, amatha kukumana ndi vuto la kuponderezana ndi matenda oyamba ndi mucous membrane. Chifukwa chake, ngati adotolo adawona kuti ndikofunikira kusankha mkazi Augmentin, kuyamwitsa kwa nthawi imeneyi kuyenera kusiyidwa.

Ngati pazifukwa zina simungatenge Augmentin EU, mutha kusankha imodzi mwazofananira zambiri zomwe zimapezeka pamsika. Chifukwa chake, malinga ndi zomwe achitazo, mankhwalawa ndi ofanana kwambiri:

• "Abiklav" ndi mankhwala osokoneza bongo opangidwa kuchokera ku zochita za amoxicillin ndi potaziyamu clavulanate. Ma anaerobes ambiri a gramu-gramu komanso gram-negative ndi ena amawaganizira. Mankhwalawa amalembera bakiteriya sinusitis, atitis media, bronchitis omwe ali pachimake, cystitis, chibayo, matenda a pakhungu ndi minofu yofewa, komanso mafupa ndi mafupa.
• A-Klaw-Farmeks ndi ufa wothandizira kukonza yankho la jekeseni wamkati. Mankhwala ndi a gulu la antibacterial wothandizirana. Maziko a antibacteria ndi osakaniza amoxicillin ndi potaziyamu clavulanate. Mankhwalawa akuwonetsa zotsatira zabwino pochiza matenda osakanikirana, matenda a ziwalo za ENT, komanso matenda ena obwera chifukwa cha bakiteriya.
• "Betaclav" ndi mankhwala ogwiritsira ntchito mwatsatanetsatane, omwe amaphatikiza amoxicillin trihydrate ndi potaziyamu clavulanate. Awa ndi miyala yaying'ono yazowoneka bwino yokutidwa ndi filimu yoyera. Ichi ndi chopanga chopangira chomwe chimatchedwa antibacterial zochita. Ilinso ndi mphamvu ya beta-lactamase inhibitor, yomwe imasankha ntchito ya tizilombo toyambitsa matenda osiyanasiyana. Mankhwalawa amalembera bakiteriya sinusitis, otitis media, bronchitis, chibayo, cystitis, komanso matenda a minofu ndi mafupa.
• Coact ndi yoyera yoyera granular pokonzekera kuyimitsidwa pakamwa. Zomwe zimapangidwira zimapangidwa ndi amoxicillin ndi potaziyamu clavulanate.Monga mankhwala am'mbuyomu, mankhwalawa amawonetsedwa ngati matenda a bakiteriya a ziwalo za ENT, kuchuluka kwa bronchitis, cystitis, pyelonephritis, komanso matenda a pakhungu, mafupa ndi minofu. Omwe amathandizira mankhwalawa amakulitsa chiwonetsero cha ntchito yake, ndikuthandizira polimbana ndi tizilombo toyambitsa matenda a penicillin.

Mayankho abwino

Ngati dokotala wakupatsani Augmentin EU, kuwunikaku kungakuthandizeni kuyang'ana ndi kusankha chomaliza pomwa mankhwalawa. Chifukwa chake, kuchokera pam ndemanga zabwino ndikofunikira kudziwa izi:

• Mankhwala amaphatikiza zinthu ziwiri zomwe zimagwira ntchito mosiyanasiyana mu antibacterial zochita,
• kuyimitsidwa kumakonzedwa mwachangu komanso mosavuta (ingowonjezerani madzi ozizira owira),
• amalimbana mwachangu ndi zovuta matenda
• Phukusili lili ndi malangizo atsatanetsatane omwe mungapeze zambiri zamankhwala,
• M'kati muli supuni, yosavuta kuyeza kuchuluka komwe kuyimitsidwa,
• mankhwalawo amununkhira bwino zipatso ndi zipatso,
• Kusintha kumawonedwa pambuyo pa tsiku loyamba la kumwa mankhwalawa (malinga ngati adasankhidwa molondola).

Ndemanga zoyipa

Malingaliro ambiri osagwirizana angamveke za mankhwala ngati Augmentin EC (kuyimitsidwa kwa ana). Ndemanga zili ndi ndemanga izi:

• alumali moyo wa mankhwalawa ndi masiku 10, chifukwa chake, ngati mulibe nthawi yogwiritsira ntchito kuyimitsidwa konse, muyenera kutaya zotsalira
• mankhwalawa amasungidwa mufiriji, chifukwa chake, nthawi iliyonse musanayambe kumwa, muyenera kuwotha kutentha.
• ngakhale pali mabulosi omwe akulawirana, kuyimitsidwa kumakhala ndi kukoma komwe sikamakondedwa ndi ana,
• akamamwa mankhwalawa, ana ambiri amayamba kudya, zomwe zimapangitsa kukhala kovuta kugwiritsa ntchito kuyimitsidwa ndi chakudya,
• ngati simutenga ndalama kuti musinthe microflora, pamakhala vuto lakukhumudwa pamimba ndi chopondapo,
• ndizovuta kuwerengera muyeso, kutengera zaka komanso kulemera kwa mwanayo (ndibwino kuti dokotala atero),
• mtengo wokwera, poyerekeza ndi mankhwala ena ofananawo (pafupifupi ma ruble 400 pa botolo lililonse).

Pomaliza

Anthu ambiri amawona kuti kumwa mankhwala osafunikira siwofunikira, chifukwa amawononga osati tizilombo tokha, komanso microflora yopindulitsa ya thupi. Komabe, pofuna kupewa zovuta zazikulu, akatswiri amapereka Augmentin EU kwa odwala awo. Kuyimitsidwa kwa ana, malangizo ogwiritsa ntchito omwe ali ndi chidziwitso chonse, amakhala ndi tanthauzo. Ngakhale kuti pali zovuta zambiri zomwe zimapezeka ndi maantibayotiki, mankhwalawa amalimbana ndi vutoli mwachangu, ndikuchepetsa vutoli kuchokera tsiku loyamba lakayendetsedwe. Koma ziyenera kukumbukiridwa kuti kudzipereka wekha sikololedwa. Mankhwalawa amayenera kuperekedwa ndi dokotala!

Kugwiritsa ntchito Augmentin EU mu mawonekedwe a ufa

Mlingo wa kukonzekera kwa Augmentin® EC umachitika molingana ndi zaka za mwana, mlingo umawerengeredwa mg mg pa kg patsiku kapena ml ya kuyimitsidwa koyimitsidwa. Kuwerengera Mlingo kumachitika pa amoxicillin ndi clavulanic acid, kupatula milandu ikamagwiritsidwa ntchito padera lililonse. Kuti muchepetse zovuta zomwe zingakhalepo kuchokera m'matumbo am'mimba ndikuwonjezera kuyamwa, mankhwalawa amayenera kutengedwa pakamwa kumayambiriro kwa chakudya. Kuchiza sikuyenera kupitilizidwa kwa masiku 14 osanenedwe za momwe matenda aliri.

Ngati ndi kotheka, ndikotheka kuchitapo kanthu pang'onopang'ono (oyamba, makonzedwe a Augmentin ® mu mawonekedwe a dosage ndi ufa wokonzekera yankho la intravenous makonzedwe, kenaka ndikusintha kukonzekera kwa Augmentin® mu mitundu ya pakamwa).

Augmentin® EU ndikulimbikitsidwa kwa ana azaka zitatu ndi kupitilira. Palibe zokuchitikirani ndi kugwiritsidwa ntchito kwa Augmentin® EC mwa ana mpaka miyezi itatu. Mlingo wovomerezeka tsiku lililonse ndi 90 mg wa amoxicillin ndi 6.4 mg wa clavulanic acid pa 1 kg ya kulemera kwa thupi, wogawidwa kawiri pa maola 12 aliwonse kwa masiku 10.

Kwa odwala omwe ali ndi makilogalamu opitilira 40, mitundu ina ya Augmentin® imalimbikitsidwa.

Malinga ndi zomwe zili mu clavulanic acid, Augmentin® EC ndi yosiyana ndi kuyimitsidwa kwina komwe kumakhala ndi amoxicillin ndi clavulanic acid. Augmentin® EC ili ndi 600 mg ya amoxicillin ndi 42.9 mg wa clavulanic acid mu 5 ml ya kuyimitsidwanso, pomwe kukonzekera kuli ndi 200 mg ndi 400 mg ya amoxicillin mu 5 ml ya kuyimitsidwa kuli ndi 28,5 mg ndi 57 mg ya clavulanic acid, motsatana mu 5 ml ya kuyimitsidwa. Kukonzekera kuyimitsidwa ndi muyezo wa 200 mg wa amoxicillin mu 5 ml, 400 mg ya amoxicillin mu 5 ml ndi Augmentin® EC sizisinthika.

Magulu apadera a odwala

Odwala ndi mkhutu aimpso ntchito

Palibe kusintha kwa mankhwalawa komwe kumafunikira pakuyimitsidwa kwa creatinine> 30 ml / min.

Mankhwalawa adapangidwa kuti agwiritse ntchito chilolezo cha creatinine

Zizindikiro zogwiritsidwa ntchito

Matenda oyambitsidwa ndi bakiteriya omwe amapezeka ndi tizilombo tating'onoting'ono tomwe timayambitsa matenda ochepa: kupuma kwam'mimba thirakiti (bronchitis, chibayo, matenda a m'mimba, zotupa zam'mapapo), matenda amtundu wa ENT (sinusitis, tonsillitis, otitis media), matenda amtundu wa genitourinary ndi ziwalo za pelvic (pyelonephritis, pyelitis, cystitis, urethritis, prostatitis, cervicitis, salpingitis, salpingoophoritis, tubo-ovarian abscess, endometritis, bakiteriya vaginitis, kuchotsa septic, pambuyo pake, sepsis, pelvioperitonitis, chancre yofewa, gonorrhea, matenda a pakhungu ndi minofu yofewa (erysipelas, impetigo, secondary koma dermatoses kachilombo, abscesses, cellulitis, bala matenda), osteomyelitis, matenda postoperative, kupewa matenda opaleshoni.

Mlingo

mapiritsi okutira, lyophilisate pokonzekera yankho la mtsempha wamkati, ufa pokonzekera kuyimitsidwa kwa makonzedwe am'kamwa, mapiritsi, ufa pokonzekera yankho la njira yolumikizira mafupa

Momwe mungagwiritsire ntchito: Mlingo ndi njira ya chithandizo

Mlingo wa Augmentin EU amaperekedwa molingana ndi amoxicillin. Mlingo wa mankhwalawa umakhazikitsidwa payekhapayekha kutengera kuwopsa kwa maphunzirowo ndi malo omwe matendawa alowa, chidwi cha tizilomboti.

Ana osakwana zaka 12 zakubadwa - mu mawonekedwe a kuyimitsidwa, madzi kapena kutsikira pakamwa. Mlingo umodzi umakhazikitsidwa malinga ndi zaka zake: ana mpaka miyezi itatu - 30 mg / kg / tsiku m'magawo awiri ogawanika, miyezi itatu ndi okulirapo - matenda opweteka kwambiri - 25 mg / kg / tsiku mu 2 mg waukulu kapena 20 mg / kg / tsiku Mlingo 3, odwala kwambiri - 45 mg / kg / tsiku mu 2 Mlingo kapena 40 mg / kg / tsiku mu 3 waukulu.

Akuluakulu ndi ana opitirira zaka 12 kapena zolemera makilogalamu 40 kapena kupitilira: 500 mg 2 nthawi / tsiku kapena 250 mg katatu kapena tsiku. Odwala kwambiri ndi matenda opatsirana thirakiti - 875 mg 2 nthawi / tsiku kapena 500 mg katatu / tsiku.

Mulingo wambiri tsiku lililonse wa amoxicillin wa akulu ndi ana opitirira zaka 12 ndi 6 ga, kwa ana ochepera zaka 12 - 45 mg / kg thupi.

Mlingo wambiri watsiku ndi tsiku wa clavulanic acid kwa akulu ndi ana opitirira zaka 12 ndi 600 mg, kwa ana ochepera zaka 12 - 10 mg / kg thupi.

Ndi zovuta kumeza mwa akulu, kugwiritsa ntchito kuyimitsidwa kumalimbikitsidwa.

Ngati matenda a impso alephera, mlingo ndi pafupipafupi waudindo zimayendetsedwa (makonzedwe a LF omwe ali ndi zinthu zomwezi kuchokera kwa opanga ena) malinga ndi QC: ndi QC yoposa 30 ml / min, kusintha kwa mlingo sikofunikira, ndi QC 10-30 ml / min: mkati - 250- 500 mg / tsiku lililonse maola 12, ndi CC zosakwana 10 ml / mphindi - 1 g, ndiye 500 mg / tsiku iv kapena 250-500 mg / tsiku pakamwa kamodzi. Kwa ana, mlingo uyenera kuchepetsedwa chimodzimodzi.

Odwala pa hemodialysis - 250 mg kapena 500 mg ya Augmentin EC pakamwa limodzi, gawo lina la 1 pa dialysis ndi wina mlingo 1 kumapeto kwa gawo la dialysis.

Zotsatira za pharmacological

Kuphatikiza kophatikizira kwa amoxicillin ndi clavulanic acid, choletsa-lactamase inhibitor. Imagwira bactericidal, imalepheretsa kapangidwe ka khoma la bakiteriya.

Yogwira pakulimbana ndi bakiteriya wa gram - kuphatikizapo beta-lactamase yopanga tizilombo ta: Staphylococcus aureus,

mabakiteriya aerobic gram-negative: Enterobacter spp., Escherichia coli, Haemophilus influenzae, Klebsiella spp., Moraxella catarrhalis.

Tizilombo toyambitsa matenda totsatirawa timangokhudza Augmentin EC mu vitro: Staphylococcus epermidis, Streptococcus pyogene, Streptococcus anthracis, Streptococcus pneumoniae, Streptococcus viridans, Enterococcus faecalis, Corynebacterium spp.

mabakiteriya osokoneza bongo a aerobic gramu-kuphatikizapo michere ya beta-lactamase): Proteus mirabilis, Proteus vulgaris, Salmonella spp., Shigella spp. ), Campylobacter jejuni,

mabakiteriya a anaerobic gram-osavomerezeka (kuphatikiza mitundu yopanga beta-lactamases): Bacteroides spp. kuphatikiza Bacteroides fragilis.

Clavulanic acid ku Augmentin EC imalepheretsa mtundu II, III, IV ndi V mitundu ya beta-lactamases, yogwira motsutsana ndi mtundu I beta-lactamases, yopangidwa ndi Pseudomonas aeruginosa, Serratia spp, Acinetobacter spp. Clavulanic acid imakhala yogwirizana kwambiri ndi ma penicillinases, chifukwa amapanga zovuta kukhazikika ndi enzyme, yomwe imalepheretsa kuchepa kwa enzymatic pansi pa mphamvu ya beta-lactamases.

Zotsatira zoyipa

Kuchokera pamiyambo ya m'mimba: kusanza, kusanza, kutsegula m'mimba, gastritis, stomatitis, glossitis, kuchuluka kwa "chiwindi" transaminases, nthawi zina - cholestatic jaundice, hepatitis, kulephera kwa chiwindi (nthawi zambiri okalamba, abambo, omwe ali ndi chithandizo chambiri), pseudomembranous ndi hemorrhagic colitis (itha kupanga pambuyo pa mankhwala), enterocolitis, lilime la "tsitsi" lakuda, kudetsa khungu la mano.

Hematopoietic ziwalo: kuwonjezereka kosinthika kwa prothrombin nthawi ndi nthawi ya magazi, thrombocytopenia, thrombocytosis, eosinophilia, leukopenia, agranulocytosis, hemolytic anemia.

Kuchokera ku dongosolo lamanjenje: chizungulire, kupweteka mutu, chithokomiro, nkhawa, kusintha kwa machitidwe, kupweteka.

Zomwe zimachitika mdera: nthawi zina, phlebitis pamalo a jekeseni wa iv.

Thupi lawo siligwirizana ndi Augmentin EU zigawo: urticaria, erythematous totupa, kawirikawiri - multiforme exudative erythema, anaphylactic mantha, angioedema, osowa kwambiri - exfoliative dermatitis, zilonda zamadzimadzi zotupa za erythema (Stevens-Johnson syndrome), matupi awo saviyo vasculitis pachimake kwambiri pantulosis

Zina: candidiasis, kukula kwa mphamvu, interstitial nephritis, crystalluria, hematuria.

Malangizo apadera

Ndi chithandizo cha maphunzirowa ndi Augmentin EU, ndikofunikira kuwunika momwe ntchito ya magazi, chiwindi ndi impso.

Pofuna kuchepetsa chiwopsezo cha mavuto obwera kuchokera m'matumbo am'mimba, mankhwalawa amayenera kumwa ndi zakudya.

Ndikotheka kukhala ndi superinitness chifukwa cha kukula kwa microflora sazindikira izi, zomwe zimafunikira kusintha kofananirana ndi mankhwala opha maantibayotiki.

Zitha kupereka zotsatira zabodza pakupanga shuga mu mkodzo. Poterepa, tikulimbikitsidwa kugwiritsa ntchito njira ya glucose oxidant pofufuza kuchuluka kwa shuga mumkodzo.

Pambuyo pa kuchepetsedwa, kuyimitsidwa kuyenera kusungidwa osaposa masiku 7 mufiriji, koma osapanga chisanu.

Odwala omwe ali ndi hypersensitivity ku penicillin, zovuta zomwe zimachitika ndi mankhwala a cephalosporin zimatheka.

Nkhani za kukula kwa necrotizing colitis mu akhanda ndi amayi apakati omwe ali ndi nthawi yopasuka ya zimitseko zinaululidwa.

Kuchita

Maantacid, glucosamine, mankhwala othandizira, aminoglycosides amachepetsa ndikuchepetsa mayamwidwe a Augmentin EC, ascorbic acid imawonjezera kuyamwa.

Mankhwala a Bacteriostatic (macrolides, chloramphenicol, lincosamides, tetracyclines, sulfonamides) amakhala ndi zotsatira zotsutsana.

Zimawonjezera kugwira ntchito kwa anticoagulants osalunjika (kupondereza microflora yamatumbo, kumachepetsa kaphatikizidwe ka vitamini K ndi index ya prothrombin). Ndi munthawi yomweyo makonzedwe a anticoagulants, ndikofunikira kuyang'anira zomwe zikuwonetsa magazi.

Amachepetsa mphamvu ya njira zakulera zam'mlomo, mankhwala, panthawi ya kagayidwe kamene PABA imapangidwa, ethinyl estradiol - chiopsezo cha magazi "kupunduka".

Ma diuretics, allopurinol, phenylbutazone, NSAIDs ndi mankhwala ena omwe amatsekerera katulutsidwe kamatulu amathandizanso kuchuluka kwa amoxicillin popanga Augmentin EC (clavulanic acid imachotsedwa makamaka ndi kusefera kwa glomerular).

Allopurinol imawonjezera mwayi wokhala ndi zotupa pakhungu.