Mapiritsi a Glurenorm - malangizo a boma ogwiritsira ntchito

Kupanga
Piritsi limodzi lili:
Chithandizo: glycidone - 30 mg,
zokopa: lactose monohydrate, wowuma chimanga wowuma, sungunuka wa chimanga, magnesium stearate.

Kufotokozera
Zosalala, zozungulira, zoyera komanso zokutira kumapeto kwa tebulo, notch mbali imodzi ndikulemba "57C" mbali zonse ziwiri, zoopsa, logo ya kampani idalembedwa mbali inayo.

Gulu la Pharmacotherapeutic:

Code ya ATX: A10VB08

Mankhwala
Glurenorm imakhala ndi pancreatic ndi extrapancreatic zotsatira. Imalimbikitsa kukonzekera kwa insulini pochepetsa pancreatic beta-cell glucose irrigation, kumakulitsa kumva kwa insulini komanso kumangiriza komwe kumalimbitsa maselo, kumakulitsa mphamvu ya insulin pakumenya kwa minofu ndi chiwindi cha shuga (kumakulitsa kuchuluka kwa insulin zolandilira timisempha tating'ono), ndikuletsa lipolysis mu adipose minofu. Machitidwe mu gawo lachiwiri la insulin katulutsidwe, amachepetsa zomwe zili m'magazi. Imakhala ndi hypolipidemic kwambiri, imachepetsa magazi a magazi. Zotsatira za hypoglycemic zimayamba pambuyo pa maola 1.0-1,5, mphamvu yayikulu - pambuyo pa maola 2-3 ndipo imatha maola 12.

Pharmacokinetics
Glycvidone imathamanga mwachangu ndipo imatsala pang'ono kulowa m'mimba. Pambuyo pakulowetsa muyezo umodzi wa Glyurenorm (30 mg), kuchuluka kwambiri kwa mankhwalawa m'madzi am'magazi kumatha pambuyo pa maola 2-3, ndi 500-700 ng / ml ndipo pambuyo maola 14-1 amatsitsidwa ndi 50%. Zimapukusidwa kwathunthu ndi chiwindi. Gawo lalikulu la metabolites limapukusidwa mu ndulu kudzera m'matumbo. Ndi gawo laling'ono chabe la metabolites lomwe limatulutsidwa mu mkodzo. Mosasamala za mlingo ndi njira yoyendetsera, pafupifupi 5% (mwa mawonekedwe a metabolites) a mankhwalawa amapezeka mumkodzo. Mlingo wa glurenorm excretion ndi impso umakhalabe wocheperako ngakhale kugwiritsa ntchito nthawi zonse.

Zizindikiro
Type 2 shuga mellitus odwala azaka zapakati ndi okalamba (ndi kusachita bwino kwa mankhwala othandizira).

Hypersensitivity kuti sulfonylureas kapena sulfonamides,

mtundu 1 shuga

matenda ashuga ketoacidosis, precoma, chikomokere,

vuto pambuyo pancreatic resection,

pachimake hepatic porphyria,

kukanika kwambiri kwa chiwindi,

zina zowawa kwambiri (mwachitsanzo, matenda opatsirana kapena maopaleshoni akuluakulu akasonyezedwa)

mimba, nthawi yoyamwitsa.

Ndi chisamaliro
Glurenorm ikuyenera kugwiritsidwa ntchito:

febrile syndrome

Matenda a chithokomiro (opuwala)

uchidakwa.

Mimba komanso nthawi yoyamwitsa
Kugwiritsa ntchito Glyurenorm pa nthawi ya pakati kumapangidwa.
Ngati muli ndi pakati, muyenera kusiya kumwa mankhwalawo ndikuonana ndi dokotala nthawi yomweyo.
Ngati kuli kofunikira kugwiritsa ntchito mankhwalawa panthawi yoyamwitsa, kuyamwitsa kuyenera kutha.

Mlingo ndi makonzedwe
Mankhwala amaperekedwa pakamwa.
Kusankhidwa kwa mlingo ndi regimen kuyenera kuchitika motsogozedwa ndi kagayidwe kazakudya. Mlingo woyambirira wa Glyurenorm nthawi zambiri amakhala mapiritsi 14 (15 mg) pakudya kadzutsa. Ngati ndi kotheka, onjezani msanga pang'onopang'ono, malinga ndi malingaliro a dokotala. Kuchulukitsa kwa mapiritsi oposa 4 (120 mg) patsiku nthawi zambiri sikuti kumabweretsa chiwonjezerocho. Ngati mlingo wa Glyurenorm wa tsiku ndi tsiku upitirire mapiritsi 2 (60 mg), angathe kutumikiridwa pa mlingo umodzi, mukamadye kadzutsa. Mukapereka mankhwala okwanira, zotsatira zabwino zitha kutheka pakumwa mlingo wa tsiku ndi tsiku womwe umagawidwa mu Mlingo wa 2-3. Pankhaniyi, mlingo waukulu kwambiri uyenera kumwedwa m'mawa. Glurenorm iyenera kumwedwa ndi chakudya, kumayambiriro kwa chakudya.
Mukamachotsa pakamwa hypoglycemic wothandizanso ndi momwe limagwirira ntchito koyamba mlingo kutsimikiza kutengera njira ya matenda pa nthawi ya mankhwala. Mlingo woyambirira nthawi zambiri umakhala piritsi limodzi 1 mpaka 1 piritsi (15-30 mg).
Ngati monotherapy sichimapereka zomwe zikuyembekezeredwa, kuthandizanso kwa biguanide ndikotheka.

Kuchokera m'mimba:
Zoposa 1%	nseru, kusanza, kudzimbidwa, kutsegula m'mimba, kusowa chilimbikitso, intrahepatic cholestasis (1 nkhani).
Dermatological:
0,1-1%	kuyabwa, chikanga, urticaria (1 kesi), matenda a Stevens Johnson.
Kuchokera ku dongosolo lamanjenje:
0,1-1%	- mutu, chizungulire, chisokonezo.
Kuchokera ku hematopoietic system:
Zoposa 0.1%	thrombocytopenia, leukopenia (1 kesi), agranulocytosis (1 mlandu).

Bongo
Hypoglycemic zinthu ndizotheka.
Pankhani ya kukhazikika kwa dziko la hypoglycemic, kukhazikitsa shuga mkati kapena kudzera m'mitsempha ndikofunikira.

Kuchita ndi mankhwala ena
Salicylates, sulfonamides, phenylbutazone derivatives, anti-tuberculosis mankhwala, chloramphenicol, tetracyclines ndi coumarin zotumphukira, cyclophosphamides, mao inhibitors, ACE inhibitors, clofibrate, β-adrenergic blocking agents, sympatholytics (hypathidt hypcine acid).
Ndizotheka kuchepetsa zotsatira za hypoglycemic pomwe mukupatsa Glurenorm ndi sympathomimetics, glucocorticosteroids, mahomoni a chithokomiro, glucagon, diazture, michere yolerera, diazoxide, phenothiazine ndi mankhwala okhala ndi nicotinic acid, barbiturates, rifampinin, fen. Kupititsa patsogolo kapena kuzindikira kwake kwafotokozeraku ndi H₂-blockers (cimetidine, ranitidine) ndi mowa.

Malangizo apadera
Ndikofunikira kutsatira mosamalitsa zomwe dokotala akufuna kuti azichulukitse kagayidwe kazakudya. Osayimitsa chithandizo nokha popanda kudziwitsa dokotala. Ngakhale glurenorm amachotsekedwa pang'ono mu mkodzo (5%) ndipo nthawi zambiri amaloledwa bwino kwa odwala omwe ali ndi matenda a impso, chithandizo cha odwala omwe ali ndi vuto laimpso liyenera kuchitika moyang'aniridwa ndi achipatala.
Odwala omwe ali ndi matenda osokoneza bongo amakhala ndi vuto la kuthamanga kwa mtima, chiwopsezo chomwe chitha kuchepetsedwa pokhapokha potsatira kwambiri zakudya zomwe zimayikidwa. Othandizira pakamwa sayenera kuthana ndi zakudya zomwe zimakupatsani mwayi wopewa kulemera kwamthupi. Onse othandizira pakamwa a hypoglycemic omwe ali ndi zakudya zosakhudzidwa kapena osagwirizana ndi mankhwalawa omwe amalimbikitsidwa angayambitse kuchepa kwakukulu kwa shuga m'magazi komanso kukula kwa boma la hypoglycemic. Kumwa shuga, maswiti, kapena zakumwa zosokoneza bongo nthawi zambiri kumathandiza kupewa kuyambika kwa hypoglycemic. Pankhani ya kupitiriza kwa hypoglycemic state, muyenera kufunsa dokotala nthawi yomweyo.
Ngati mukumva kusowa bwino (malungo, zotupa, mseru) mukamalandira chithandizo ndi Glurenorm, muyenera kufunsa dokotala nthawi yomweyo.
Ngati thupi lanu lisanafike, muyenera kusiya kumwa Glyurenorm, m'malo mwake ndi mankhwala ena a hypoglycemic kapena insulin.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu
Mukamasankha mlingo kapena kusintha kwa mankhwalawa, muyenera kupewa kuchita zinthu zomwe zingakhale zoopsa zomwe zimafunikira chidwi chochulukirapo komanso kuthamanga kwa zochitika zama psychomotor.

Kutulutsa Fomu
30 mg mapiritsi
Pamapiritsi 10 mu chotchinga matuza (chithunthu) kuchokera PVC / Al.
Kwa matuza 3, 6 kapena 12 okhala ndi malangizo ogwiritsira ntchito pabokosi lamatoni.

Malo osungira
Pamalo ouma, pamtunda wosaposa 25 ° C.
Pewani patali ndi ana!

Tsiku lotha ntchito
Zaka 5
Osagwiritsa ntchito tsiku lotha ntchito likusonyezedwa pa phukusi.

Tchuthi kuchokera ku malo ogulitsa mankhwala
Ndi mankhwala.

Wopanga
Beringer Ingelheim Ellas A.E., Greece Greece, 19003 Kings Avenue Pkanias Markopoulou, 5th km

Ofesi yoimira ku Moscow:
119049, Moscow, st. Donskaya 29/9, nyumba 1.