Glyformin wa matenda ashuga

Gliformin ndi mankhwala apiritsi kuti muchepetse shuga. Amawonetsedwa poyang'anira njira ya matenda a shuga a 2, makamaka kuphatikiza kunenepa. Kuti muchepetse kunenepa, odwala matenda ashuga amalembedwa 1500 mpaka 3000 mg ya mankhwalawa, omwe amagawidwa pawiri. Zovomerezeka pakuchepetsa thupi - kudya komanso kuchita masewera olimbitsa thupi.

Odwala kwambiri matenda a chiwindi ndi impso, mtima kulephera. Munthawi ya mankhwalawa, muyenera kuyang'anitsitsa chizindikiro cha shuga, kutenga magazi ndi mkodzo miyezi itatu iliyonse, simungathe kumwa mowa. Zotsatira zoyipa kwambiri ndizovuta zam'mimba, kutsegula m'mimba, ndipo owopsa kwambiri ndi lactic acidosis (kupweteka pamimba, minofu, nseru, kusowa chikumbumtima).

Werengani nkhaniyi

Zofunikira pa Glformin

Gliformin ndi mankhwala ochepetsa shuga wa magazi, ogwiritsidwa ntchito ngati mtundu 2 wa shuga. Makhalidwe ake akuluakulu akuwonetsedwa patebulopo.

Glformin Prolong ndi piritsi la 1000 mg ndikutulutsa pang'onopang'ono kwa zinthu zomwe zikugwira. Amawerengedwa kuti ndi ofatsa, osayambitsa zovuta m'mimba. Kutulutsidwa kotere ndikwabwino kuposa masiku onse chifukwa kuphatikizika kwa metformin m'magazi kumayendetsedwa.

Ndipo pali zambiri za mankhwala a Metformin a shuga.

Njira yamachitidwe

Metformin amachepetsa shuga m'magazi kunja kwa chakudya komanso mukatha kudya. Amachita monga magawo a carbohydrate metabolism:

• chiwindi - imalepheretsa kupangidwa kwa mamolekyulu atsopano a shuga, kuletsa kuwonongeka kwa nkhokwe za glycogen, kumathandizira mapangidwe ake,
• minofu - kumawonjezera kukhudzika kwa maselo kukoka kwa insulin, glucose amatengedwa kuchokera magazi mwachangu ndipo amaphatikizidwa ndi zomwe zimachitika pakupanga mphamvu,
• matumbo - Imachepetsa mayamwidwe am'madzi, imalimbikitsa kukhathamiritsa kwawo.

Chimodzi mwazinthu zabwino za mankhwalawa ndi mtundu wa mafuta kagayidwe. Mankhwala amachepetsa cholesterol ndi triglycerides, amachepetsa zomwe zili osalimba a lipoproteins omwe amapanga mapangidwe a atherosranceotic malo. Kuphatikiza pa kadyedwe komanso masewera olimbitsa thupi, zimathandizira kuchepetsa thupi, koma pazokha zimapereka mphamvu yoperewera akachepetsa thupi.

Kugwiritsa ntchito Glformin kwa odwala omwe ali ndi matenda a shuga a 2 kumachepetsa chiopsezo cha kukula:

• mtima matenda ashuga (nephropathy, angiopathy, retinopathy) ndi 30%,
• 40% myocardial infarction ndi stroke,
• kufa kwa matenda ashuga ndi zotsatira zake ndi 42%.

Zisonyezo za mapiritsi a glyformin

Mapiritsi a Gliformin amawonetsedwa pochiza matenda amtundu wa 2 shuga. Amagwiritsidwa ntchito ngati njira yayikulu osakwanira pazoletsa kudya komanso kuchuluka kwa mphamvu, ndipo amathanso kuphatikizidwa ndi mankhwala ena, jakisoni. Aperekedwa kwa odwala matenda ashuga onenepa kwambiri. Amalembera achikulire ndi ana kuyambira azaka 10, achinyamata.

Glyformin itha kugwiritsidwanso ntchito poletsa kusinthasintha kwa prediabetes kuti itayike shuga 2.

Prophylaxis yotere imalembedwa kwa odwala omwe ali pachiwopsezo:

• kunenepa
• matenda a shuga
• matenda a shuga m'magazi a mzere woyamba (makolo, abale, mlongo),
• kuwonjezeka kwa triglycerides ndi kuchepa kwapacroteins okwera (kuteteza ziwiya kuchokera ku cholesterol).

Contraindication

Metformin ndi mankhwala onse omwe atengera izi, kuphatikiza Glformin, salimbikitsidwa kuti:

• kuchepa kwa kusefukira kwa impso,
• tsankho
• kuchuluka kwa matupi a ketone m'magazi ndi mkodzo (ketoacidosis) - kupuma kwamkati komanso kupuma pafupipafupi, kununkhira kwa acetone mumlengalenga wotuluka,

• Zizindikiro za matenda a shuga (kudandaula kwambiri, kuthina, kuthamanga kwa mtima, kusokonezeka thupi, kuyankhula mosokonezeka, kufooka miyendo).
• kusowa kwamadzi
• matenda oopsa
• dontho lakuthwa magazi.
• mawonekedwe
• Kulephera kwa m'mapapo - kufupika, kupweteka kwa mphumu, khungu lamtambo,
• zovuta zamagazi - kupuma movutikira, kuchuluka kwa mtima, kutupa, kulemera mu hypochondrium yoyenera,
• myocardial infaration m'mwezi woyamba,
• matenda a chiwindi - chiwindi, matenda enaake,
• poyizoni wambiri kapena wosakhazikika, uchidakwa.

Momwe mungatenge Glformin kuti muchepetse kunenepa

Gliformin yokhudza kuwonda imatha kuchitika pokhapokha ngati kuphwanya kagayidwe kazakudya - prediabetes kapena matenda a shuga a 2. Mlingo woyamba wa munthu wamkulu ndi 500 mg katatu patsiku. Ndikwabwino kumwa piritsi ndi madzi mukamadya kapena mutangomaliza kudya.

Pambuyo pakugwiritsa ntchito milungu iwiri, kuyezetsa magazi ndi shuga komanso kuyesa kwa glucose kuyenera kumwedwa. Malinga ndi zomwe zalandiridwa, mlingo umatha kukula pang'onopang'ono. Ngati ndi kotheka, amabweretsedwa kwa 3000 g patsiku, logawidwa pazigawo zitatu.

Katswiri wa Endocrinology

Chithandizo cha Gliformin ndi insulin

Glformin ikhoza kuphatikizidwa ndi jakisoni wa insulin. Kufunika kwa chithandizo chophatikizira chotere kumachitika chifukwa cha matenda ashuga amtundu wa 2, pomwe sizingatheke kupewa zovuta zamitsempha zokha. Nthawi zambiri kukana mankhwala achikhalidwe kumachitika ndi nthawi yayitali ya matendawa kapena kuwonjezeranso matenda ena, kufunika kogwira ntchito.

Gulu lachiwiri lazomwe zikuwonetsa ndizotsatira zochepa za insulin mu mtundu 1 wa shuga, womwe umakonda kwambiri achinyamata. Gliformin amagwiritsidwa ntchito muyezo wa 500 kapena 850 mg kawiri patsiku, ndipo muyezo wa timadzi timene timasankhidwa malinga ndi zomwe zili m'magazi komanso kuchuluka kwa chakudya chamagulu (chakudya) mu gawo la chakudya.

Onani vidiyo yokhudza chithandizo cha matenda a shuga a mtundu wa Glatiniin:

Malangizo a ana

Mwa ana ndi achinyamata, Gliformin wakhala akugwiritsidwa ntchito kuyambira zaka 10. Yambani ndi 500 mg kapena 850 mg kamodzi tsiku lililonse. Pambuyo masiku 10 kusintha kwa mankhwalawa kumafunikira. Pazomwezi, kuyezetsa magazi kumayikidwa ndipo malinga ndi data yomwe idalandiridwa, mlingo umachulukitsidwa kapena kusiyidwa wosasinthika.

Kuwonjezeka pang'onopang'ono ndikofunikira kuti pakhale kupirira kwa mankhwalawa, chifukwa nthawi zambiri zimayambitsa zovuta m'mimba m'masiku oyamba kugwiritsa ntchito. Kuchuluka kwa metformin isanafike zaka 16 kumaganiziridwa kuti 2000 mg patsiku, kufalitsidwa pa 2 waukulu.

Kodi ndizotheka kubereka, kuyamwa

Metformin amadutsa pamtunda kupita kwa mwana wosabadwa, chifukwa chake sayenera kugwiritsidwa ntchito panthawi yomwe ali ndi pakati. Mosasamala mtundu wa shuga, azimayi amasamutsidwa ku insulin.

Chifukwa chodutsa mkaka wa m'mawere, mankhwalawa Glyformin sangalembedwe kuyamwa. Komabe, palibe umboni kuti ngakhale Mlingo wokwera kwambiri unayambitsa zovuta m'magulu awa a odwala kapena anali owopsa pakukula kwa mwana.

Kodi glyformin ndi mowa zingaphatikizidwe

Mukamamwa Glformin, mowa umatsutsana, komanso mankhwala onse omwe amakhala ndi ethyl mowa. Kuphatikiza uku kumawonjezera chiopsezo cha mavuto, makamaka kuphatikizira kwa poizoni wa lactic acid (lactic acidosis).

Kuopsa kumawonjezeka ndikusala kudya komanso kutsatira zakudya zopatsa mphamvu zopatsa mphamvu, matenda a impso kapena chiwindi.

Kodi bongo umachitika

Mukamamwa Mlingo waukulu kwambiri, wopitilira muyeso ndi nthawi 50 kapena kuposerapo, pamakhala vuto lactic acidosis.

Zizindikiro za poyizoni:

• kufooka mwadzidzidzi
• kusanza, kusanza,
• kutsegula m'mimba
• kupweteka kwa minofu
• kutsika kwa kuthamanga kwa magazi ndi kutentha kwa thupi,
• kugunda kwa mtima
• m'mimba kukokana
• kupuma pafupipafupi komanso kosaya
• chizungulire
• chikumbumtima.

Ngati chithandizo choyambirira (chapamimba cha m'mimba) sichinaperekedwe, kenaka chisamaliro chachikulu sichingachitike mu chipatala (otsitsa ndi mayankho, kuyeretsa magazi pachiwonetsero), ndiye kuti zotsatira zake zingathe.

Zotsatira zoyipa

Vuto lalikulu lomwe limagwiritsidwa ntchito pogwiritsa ntchito Glformin ndi kupweteka, kutulutsa m'mimba, kuchepa m'mimba komanso kusowa chilakolako chofuna kudya, vuto losasangalatsa. Amadziwika kwambiri mu masiku 10 oyambirira a chithandizo. Chifukwa chake, tikulimbikitsidwa kuti muyambe kumwa ndi mlingo wochepa ndikuwonjezera pang'onopang'ono pazofunikira.

Zotsatira zoyipa siziphatikizapo:

• kutsika kwa vitamini B12, ndikugwiritsa ntchito nthawi yayitali, kuyenera kuphatikizidwa ndi mankhwala,
• chiwindi cholephera kugwira ntchito,
• kusayenda kwa bile
• zotupa pakhungu, kuyabwa, redness.

Malangizo apadera

Mwa zovuta zonse zomwe zimachitika ndi chithandizo chamankhwala ndi Glformin, lactic acidosis imawonedwa ngati yoopsa kwambiri. Popanda kuchitapo kanthu mwachangu, zimatha kupha. Zoyambitsa chiwopsezo:

• matenda akulu a impso kapena chiwindi,
• kuchuluka kwa shuga m'magazi (kuyambira 10 mmol / l),
• ketoacidosis
• kusala
• kupuma komanso kulephera kwa mtima,
• kulimbikira ntchito, masewera olemetsa.

Mankhwalawa sangathe kugwiritsidwa ntchito masiku awiri kale komanso masiku awiri atachitidwa opaleshoni kapena kuyambitsa chinthu cha radiopaque ndi ayodini m'maphunziro a kuzindikira. Ngati muli ndi matenda a impso, ndikofunikira kufufuza mozama ndikuwunika kuchuluka kwa mkodzo musanayambe kugwiritsa ntchito.

Kenako kuwongolera ntchito yawo kumafunika nthawi 1 pachaka (pakalibe ma pathologies) komanso mpaka kanayi pachaka mwa okalamba, kuwonongeka kwaimpso, komanso mankhwalawa omwe amachepetsa kuthamanga kwa magazi, okodzetsa, odana ndi kutupa.

Njira zopewera mosamala mukamatenga Glformin zimaphatikizapo:

• Pokhala ndi zakudya zamafuta ochepa, sizingatheke kuchepetsa mphamvu pansipa 1000 kcal patsiku,
• chakudya uyenera kugawidwa pakati pa chakudya,
• osachepera 1 pamwezi kuti muwunike zotsatira za chithandizo.

Metformin kapena Glyformin - ndibwino?

Ndizosatheka kudziwa chomwe chimagwiritsidwa ntchito kwambiri pa matenda a shuga - Metformin kapena Glformin, popeza onse ali ndi mawonekedwe ofanana. Chifukwa chake, mankhwalawa omwe amafunsidwa sakusintha kwa metformin, koma dzina la malonda. Mwa mankhwala onse oterewa, Glucophage amadziwika kuti ndiothandiza kwambiri, chifukwa ndi mankhwala oyamba omwe adadutsa mayesero onse azachipatala.

Mtengo wa mankhwala

Mtengo wapakati wa Glformin ndi ma ruble 234 a phukusi lomwe lili ndi mapiritsi 60 a 1000 mg aliyense, pamlingo wa 500 mg muyenera kulipira ma ruble 95, ndipo 850 mg itenga ruble 140. Glformin Pronge silipezeka pano pamakampani ogulitsa mankhwala.

Ndipo nazi zambiri zamitundu ya matenda ashuga.

Gliformin amagwiritsidwa ntchito ngati matenda a shuga a 2, makamaka kunenepa kwambiri. Amafotokozera mosamala okalamba, imaphatikizidwa mu matenda a impso ndi chiwindi. Mankhwalawa sagwirizana ndi mowa.

Metformin imakonda kutumikiridwa ndi matenda a shuga a mtundu wachiwiri. Komabe, kugwiritsa ntchito mapiritsi kumaloledwa ngakhale chifukwa chopewa. Mlingo wa mankhwalawa amasankhidwa payekha. Za mphamvu ya mankhwala a Metformin, nthawi yochuluka motani, werengani munkhaniyi.

Chimodzi mwa mankhwala abwino kwambiri ndi shuga. Mapiritsi amathandizira pochiza mtundu wachiwiri. Momwe mungamwe mankhwalawo?

Gulu la odwala matenda a shuga

Amadziwika kuti matenda a shuga ndi amtundu 1 ndi 2. Kusiyana pakati pa matendawa kumaperekedwa pagome.

Monga tikuwonera patebulo, ngati matenda amtundu woyamba a shuga atha kukhala matenda owopsa omwe amachitika pakakhala mavuto amtundu kapena matenda amtundu, ndiye kuti matenda a shuga 2, kwakukulu kwambiri, ndi matenda amoyo, zotsatira za kupsinjika kwakukulu kwa thupi miyambo ya shuga ndi mafuta akudya. Pokhala ndi zizindikiro zochepa za ntchito, maziko abwino amapangidwa, pomwe kulephera kumachitika.

Kodi matenda ashuga ndi chiyani?

Glucose, osagwiritsidwa ntchito ndi insulin pazifukwa zosiyanasiyana, amakhudza kwambiri makoma amitsempha yamagazi. Zowonongeka kuchokera mkati - microtraumas zimawonekera pamalo akalowa. Mukuvulala kumeneku, tinthu tambiri tamafuta tomwe timayikidwa m'magazi chifukwa cha zolakwika zakudya zimasungidwa. Pang'onopang'ono magawo onse atsopano a lipids amawonjezeredwa, komanso kuwonongeka kwatsopano kwa mitsempha yamagazi.

Zofunika!Kwa kanthawi kochepa, kupendekera kwapang'onopang'ono kwa lumen kumachitika, kutsekeka kwa ziwiya kumatsika, kukakamizidwa mwa iwo kumawonjezeka - atherosulinosis imachitika.

Chifukwa cha matenda oopsa, kuwonongeka kwa ma cell a mtima kumatheka. Kanthu kakang'ono kwambiri kamene kamakhala ndi minyewa yomwe imatuluka kumatha kubweretsa embolism - kufalikira kwa chotengera. Kupezeka kwa magazi m'malo ena kumayima, komwe kumayambitsa necrosis. Ndi njira imeneyi yomwe imayambitsa zinthu zoopsa monga ischemia ya mtima (ndikumalizira komaliza mu mawonekedwe a myocardial infarction) komanso kupsinjika kwa ischemic, nthawi zambiri kumabweretsa kulumala.

Thandizo ndi matenda a shuga

Ngati chithandizo cha matenda a shuga 1 amalembedwa bwino ndipo sichimayambitsa kusiyana, ndiye kuti mtundu wachiwiri wa matenda mwachindunji umatengera kuwongolera kwakanthawi kofunikira komanso kakhalidwe. Ndikofunikira kupereka:

• kudya mafuta kwakanyama,
• kuletsa kudya mafuta osavuta,
• kugwiritsa ntchito shuga kupanga mphamvu mthupi.

Ndizovuta ndendende zomwe mankhwala a Glformin atha kuthana nawo (ndi kutenga nawo gawo ponyamula matenda).

Zofunika!Mankhwala amayenera kutumizidwa ndi dokotala, mankhwala ake omwe amamwa okha ndiwowopsa.

Khalidwe la mankhwala

The zikuchokera mankhwala a Glyformin

Ngati simukutsata mawu, ndiye kuti mphamvu ya mankhwalawa ndikutulutsa shuga yemwe walowa m'thupi kumalo komwe kumachitika kwambiri - minofu. Zotsatira zake, kugwiritsa ntchito insulin kumayambitsanso. Ndipo kukonzanso kwathunthu kwa glucose kumachitika, kuthekera kwa kusintha kwa zochulukirapo kukhala lipids ndi kuziyika kwawo m'malo am'mafuta kumachotsedwa.

Wosanjikiza mafuta kumapeto amachepetsa - ndi malire a maswiti, mphamvu zimabwera zochepa, ndipo zosungika zomwe zimagwiritsidwa ntchito zimatha. Chozungulira chikutseka: metabolic normalization imachitika, ndipo matenda amtundu wa 2 amachiritsidwa.

Kugwiritsa ntchito mankhwala osokoneza bongo

Zisonyezero ndi contraindications kwa mankhwala Glformin

Gliformin ku maiko aku Europe ndi Asia amagwiritsidwa ntchito kokha matenda a shuga, monga mankhwala akuluakulu a mtundu wachiwiri komanso monga adjunct koyambirira. Amakhulupilira pano kuti, osalumikizana ndi insulin, mankhwalawa ndi osathandiza kapena owopsa. Ndipo ku America amagwiritsidwa ntchito kale (ndipo osachita bwino) ngati njira yolimbana ndi kunenepa kwambiri.Inde, kuwonjezera pakupereka shuga kwa owongolera, minyewa, Glformin imaletsa kulowa kwake mu minofu m'matumbo, komanso amachepetsa kuchuluka komwe kumayendetsedwa m'chiwindi. Kufufuza ku Russia pankhaniyi ya mankhwala akupitilizabe. Pakadali pano, Glformin wagwiritsidwa ntchito bwino ndi odwala matenda a shuga.

Zofunika!Ku Russia, mankhwalawa sawunikidwa kuti athane ndi kunenepa kwambiri.

Mawonekedwe ndi okhutira

Gliformin ndimakonzedwe a piritsi. Izi zimathandizira kwambiri ndikukulitsa mwayi womwe ungaikidwe paudikidwe wake.

Glyformin mapiritsi

Piritsi ndi yofanana ndipo ndi wozungulira kapena wozungulira wosanjikiza (kutengera malo omwe akupanga) wa mtundu woyera (zonunkhira zonona ndizotheka - zotulukirapo zowonjezera) ndi chizindikiro ndi chamfer.

Monga gawo la piritsi, mafilimu ocheperako amawonjezeredwa ndi othandizira metformin (hydrochloride), omwe samathetsa kugundana kwa chinthu chachikulu.

Zolemba ntchito

Gliformin imalembedwa kwa odwala onenepa omwe ali ndi matenda amtundu wa 2 kuti awonjezere phindu la mankhwala. Mlingo weniweniwo umatsimikiziridwa ndi adokotala, kutengera zotsatira za kuyesedwa koyambirira kwa wodwalayo. Zomwe zimachitika poyambirira kwa mankhwala atsopano zimaphunziridwa mosamala, ndiye kuchuluka kwake komanso pafupipafupi kwa masana kumasinthidwa.

Ndikofunikira! Udindo waukulu wamankhwala amtundu wachiwiri wa shuga suwoperekedwa ku mankhwala, koma kutsata zomwe dokotalayo amalimbikitsa pakusintha kwa moyo, popanda kupanga zakudya zopatsa thanzi komanso kuwonjezera minofu, kumwa mankhwalawa kulibe ntchito..

Mlingo ndi makonzedwe a mankhwala a Glyformin a shuga

Mankhwalawa amalimbikitsidwa koyamba pang'onopang'ono (1/2 piritsi 1 patsiku), ndipo ngati kuli kotheka, onjezani mlingo pang'onopang'ono (mpaka mapiritsi atatu patsiku). Kukhazikitsidwa kwa chizolowezi chatsiku ndi tsiku kumachitika motsutsana ndi maziko azowona za zizindikiro za shuga ndikuwunika mphamvu ya kutsika kwawo.

Mapiritsi amatengedwa nthawi yomweyo ndi chakudya kapena mukangomaliza kudya, osafuna kutafuna, amamwa madzi ambiri.

Zotsatira zoyipa

Ngati mumanyalanyaza malangizowo ndikumamwa mankhwalawa ngati muli ndi zotsutsana kapena popanda mankhwala a dokotala, vuto lanu langozi - lactic acidosis imayamba. Uku ndikulakwika kwa thupi ndi kuchuluka kwa lactic acid m'misempha ndi zovuta zake kuchoka. Ambiri mwa odwala omwe adachita lactic acidosis ali ndi matenda ashuga omwe amamwa mankhwalawa kwa ma Biguanides angapo, omwe Glformin ndi ake. Ngati sanalandire, lactacitosis imathera pangozi.

Zotsatira zoyipa za mankhwalawa

Zizindikiro zamavuto, zomwe zikusonyeza momwe angachitire acidic:

• kufooka wamba, hypotension, kutsika kwa mtima (bradycardia),
• matenda a dyspeptic - nseru, matumbo, m'mimba,
• kupweteka kwa minofu ndi kukokana
• chizungulire, chisokonezo, kukomoka, chikomokere.

Ndiopseza lactic acidosis, kugonekedwa kwa chipatala kumachitika nthawi yomweyo, ndikutsata njira zodzutsira ndikadali pamsewu. Muzovuta kwambiri, hemodialysis imafunika.

Chifukwa chake, chithandizo cha Gliformin sichinthu chovomerezeka, koma chothandiza kwa odwala omwe ali ndi matenda amtundu wa 2 omwe alibe zotsutsana ndi mtundu uwu wa chithandizo. Cholemetsa chachikulu chochotsa matendawa chimakhala m'manja mwa wodwalayo: kukula kwa moyo wake wamtsogolo kumadalira kulanga kwake, kufunitsitsa kusintha moyo wake, kusasinthasintha pakukonzekera mapulani omwe amatsogozedwa ndi udokotala. Ndipo Glyformin, chifukwa cha mawonekedwe ake apadera, amangothamangitsa pang'ono njira yobwererera m'moyo wabwino.

Kufotokozera za mankhwalawa

Dzina ladziko lonse la mankhwalawa ndi Metformin. Mapiritsi a Glyformin amatha kutulutsa shuga m'magazi. Mankhwalawa amalimbikitsidwa pochiza matenda osokoneza bongo omwe amadalira matenda a shuga (mtundu II matenda ashuga) ngati mankhwala othandizira amadya sawonekeratu. Monga mankhwala othandizira, Glyformin amagwiritsidwanso ntchito ngati mtundu 1 wa shuga (wodalira insulin).

Gliformin ndi mankhwala osokoneza bongo a hypoglycemic omwe amaperekedwa kwa mitundu yonse ya shuga

Mphamvu ya Glformin pa thupi la munthu imawonetsedwa m'njira ziwiri: mbali inayo, imalepheretsa kupangika kwa shuga mu chiwindi, mbali inayo, imalepheretsa kuyamwa kwa zinthu m'mimba. Nthawi yomweyo, njira yogwiritsira ntchito glucose mu minofu imakulitsidwa, ndipo kumva kwa minyewa yokhudzana ndi insulin kumakulitsidwa.

Kuphatikiza apo, mankhwalawa amatha kuchepetsa njala, amachepetsa kuchuluka kwa mafuta ndi mafuta m'thupi m'magazi a m'magazi. Chifukwa chake, wodwalayo ali ndi mwayi wochepetsa thupi, ndipo monga mukudziwa, kunenepa kwambiri ndi chimodzi mwazomwe zimayambitsa matenda a shuga a 2.

Kutulutsa mafomu ndi kapangidwe kake

Gliformin imapezeka m'mitundu ingapo:

1. Mapiritsi oyera oyera kapena oyera pafupifupi oyera okhala ndi chamfer ndi chiwopsezo. The yogwira ndi metamorphine hydrochloride. Monga zogwirizana ndi zinthu:
   • sorbitol
   • calcium phosphate
   • polyvinylpyrrolidone (povidone),
   • polyethylene glycol,
   • calcium stearate kapena stearic acid.
2. Mapiritsi okhala ndi biconvex chowulungika cha oyera kapena mtundu wa kirimu. Zomwe zimagwiritsidwa ntchito ndizofanana, koma kuchuluka kwa 0,85 g pa piritsi limodzi. Amathandizira ndi wowuma wa mbatata, povidone ndi stearic acid. Utoto wamtunduwu umakhala ndi hypromellose, polyethylene glycol, talc.
3. Mapiritsi okhala ndi utoto oyera kapena amtundu wa zonona, oval, biconvex, koma okhala ndi 1 g yogwira ntchito malinga ndi piritsi limodzi. Odzilandira chimodzimodzi. Membrane wamakanema amapangidwa pamaziko a hypromellose, macrogol ndi talc.

Zotsatira zoyipa

Panthawi ya makulidwe a Gliformin, kulawa kwazitsulo mkamwa, kunyansidwa pang'ono ndi kutaya chilakolako chokwanira ndizotheka. Odwala ena nthawi zina amakhala ndi matupi awo sagwirizana, zizindikiro za lactic acidosis zimapezeka:

• kupweteka kwa minofu
• kupweteka kumbuyo kwa sternum
• Zizindikiro zam'maso
• mphwayi
• kupumira msanga
• kusowa tulo kapena kugona.

Pogwiritsa ntchito mankhwalawa kwa nthawi yayitali, mayamwidwe a vitamini B12 amachepa.

Mlingo wa matenda ashuga

Gliformin amagwiritsidwa ntchito mosamalitsa monga momwe dokotala wamulembera pamankhwala omwe amalumikizidwa kwambiri ndi momwe wodwalayo alili komanso kuchuluka kwake kwa shuga.

Zofunika! Kuphwanya Mlingo wa mankhwalawa kungayambitse zotsatira zoyipa ndikuchepetsa kuchiritsa kwa mankhwalawa.

Gliformin imayamba ndi Mlingo wochepa, pakapita nthawi kuchuluka kwa mankhwalawa kumachulukitsa, pang'onopang'ono kubwera pamlingo wokonza.

Chithandizo chogwira ntchito cha Gliformin ndi metamorphine hydrochloride

Mapiritsi ayenera kumwedwa kwathunthu, osaphwanya ndi kutafuna, ndi chakudya kapena mukangodya. Mankhwalawa ayenera kutsukidwa ndi kapu ya madzi. Kuti muchepetse zotsatira zoyipa za mankhwalawa m'matumbo, muyezo wa tsiku ndi tsiku umagawika katatu (kutengera mtundu wa mankhwalawo).

Analogi za Glyformin - gome

* Mankhwalawa onse amalembedwa kuti agwiritsidwe ntchito ndi amayi apakati ndi amayi oyamwitsa, komanso ana osakwana zaka 10.

Mankhwala Osokoneza bongo - Gallery

Kukonzekera kulikonse kwa metformin kumathandizira kugaya chakudya. Tsoka ilo, izi sizoyenera kupewa. Ndikukulangizani kuti mugwiritse ntchito Siofor, kwa Glyformin wambiri, metformin yemweyo, koma bwino koposa. Ndizokwera mtengo kwambiri kuposa Formetin ndi Metformin, koma mwina zingakhale bwino.

Shakertdinova Inna

http://www.forumdiabet.ru/topic2094.html

Chifukwa chake, nditabereka, madokotala adandipatsa mtundu wa shuga 2 ndikuyika pa Glyukafazh 1000, koma nthawi ndi nthawi palibe ndipo ndimapeza glyformin (0.5) kapena formentin (0.5), kenako pali vuto, ndimamwa glucafage m'mawa ndi madzulo piritsi, ndipo likukonzekera kuti muyenera kumwa mankhwalawa m'mawa 2 zidutswa (0,5 + 0,5) ndi madzulo 2 zidutswa, koma malangizo akuti osamwa zoposa 0,5 (piritsi limodzi) panthawi, zimapezeka kuti muyenera kumwa pakapita nthawi, zomwe sizimalipira shuga.

mila25

http://www.dia-club.ru/forum_ru/viewtopic.php?f=26&t=12763

Matenda a shuga ndi matenda oopsa omwe amavuta kuchiritsa. Mwamwayi, makampani amakono opanga zamankhwala amatha kupereka ndalama zothandizira polimbana ndi matenda. Koma aliyense ayenera kumvetsetsa kuti kugwiritsa ntchito mankhwalawa molondola komanso kutsatira zomwe dokotala wakupatsani ndi zomwe zingachititse kuti akhale bwino.

Malangizo ogwiritsira ntchito Gliformin pochiza matenda ashuga

Mankhwalawa ndi a gulu la pharmacological la biguanides, limapezeka ngati mapiritsi oyera. Chida chogwiritsa ntchito formula ya mankhwala ndi metformin, yomwe ntchito yake ndikuchepetsa kuyamwa kwa glucose kuchokera m'matumbo, kuyimitsa hepatic gluconeogeneis, kukulitsa chidwi cha insulin, kuthetsa kunenepa kwambiri, komanso kuthandizira kapamba. Mankhwala akulowa zokhudza zonse kufalikira, kufika pazipita plasma ndende 2 patatha limodzi mlingo.

Metabolism imachitika m'chiwindi, metabolites yopanda kanthu imakhudzidwa ndi impso. Panthawi yakusokonekera kwa ziwalo izi, tikulimbikitsidwa kusankha njira yina. Gliformin ndi mtundu wa mankhwala a 2 a shuga omwe amathandizidwa pa monotherapy, kuphatikizapo mankhwala ena a hypoglycemic omwe ali ndi njira yolumikizira. Kuchepetsa thupi ndi gawo limodzi lothandizira bwino ngati wodwala amatsatira zomwe akuwonetsa. Pambuyo pa maphunziro oyamba, mutha kukhazikika pang'onopang'ono, kupewa kudya, kusinthanitsa maubwenzi a magazi.

Mwa zomwe akuphwanya, ndikofunikira kuwunikira zotsutsana zotsatirazi:

• kukanika kwa impso ndi chiwindi,
• matenda a shuga
• uchidakwa wambiri,
• mimba
• yoyamwitsa
• kukhudzika kwa ziwalo,
• ntchito zokhudza insulin mankhwala.

Momwe mungamwere mapiritsi a shuga

Mlingo wa tsiku lililonse wa mankhwalawa umatengera shuga. Chithandizo chimayikidwa palokha. Malangizowo akuti mlingo woyambirira wa mankhwala a Glyformin a shuga patsiku ndi 0.5-1 g Pambuyo pa masabata awiri, mankhwalawa amatha kuwonjezeka pang'onopang'ono, kutengera mtundu wa glycemia. Ndi mankhwala okonza, amaloledwa kutenga 1.5-2 g patsiku, koma osapitilira 3 g.

Mapiritsi a shuga awa ndi ogwiritsira ntchito pakamwa. Mlingo wa tsiku ndi tsiku umagawidwa pamlingo waukulu wa 2-3, kupewa mavuto, kupatula milandu ya bongo. Matenda a chiwindi ndi impso, mfundo zomwe ziyenera kuperekedwa ziyenera kuchepetsedwa kuti muchepetse lactic acidosis. Mapiritsi 2 a shuga amathandizidwa kuti amezedwe, ndikumwa madzi ambiri. Pambuyo kuthandizira kutha kwa mankhwalawa, sinthani kumwa pang'onopang'ono kwa thupi pang'onopang'ono, apo ayi zotsatira zoyipa zimatheka.

Wodwala akapatsidwa mankhwala Glyformin wa matenda a shuga, ndikofunikira kudziwa mtengo wake. Mutha kugula mankhwala mu mankhwala, koma choyamba onani kuchuluka kwa yogwira. Glyformin 1000 mg, 850 mg, 500 mg amapezeka pamalonda. Mankhwalawa amapereka kuchepa msanga kwa magazi.

Gliformin (mapiritsi), 500 mg

Gliformin (mapiritsi), 850 mg

Gliformin (mapiritsi), 1000 mg

Maganizo a anthu a shuga a Glformin

Oksana, wazaka 42. Ndakhala ndikudwala kwa nthawi yayitali. Adamwa kale mankhwala ambiri m'moyo wake, koma onse anali ndi vuto la Mediocre. Mapiritsi awa a anthu odwala matenda ashuga asanduka chipulumutso chenicheni. Ndakhala ndikutenga Glformin pothandizira matenda a shuga kwa miyezi ingapo, ndikumva bwino. Dotoloyo akuti kuchuluka kwa magazi ake kubwerera mwakale, kumangokhala kokha.

Ilona, ​​wazaka 43 sindikuwonetsa zithunzi za mawonekedwe anga osinthika, koma ndikuvomereza moona mtima kuti mapiritsiwa adandithandizira kuti ndichepetse kunenepa kwambiri. Ndi matenda ashuga ndizovuta kwambiri, koma ndidakwanitsa. Ndikutenga maphunziro achitatu: shuga wanga wamwazi wayamba kuchepa, kunenepa kwambiri kwapita, kupuma movutikira komanso thukuta lochuluka kwatha, thanzi langa latha.

Sveta, wazaka 45 ndinakana ntchitoyo, chifukwa atatenga zotsatira zoyipa adayamba. M'malo mwanga, uku ndi kugaya kwakuya kwambiri komanso kufooka kwathunthu m'thupi. Amayenda ngati ntchentche yogona, kotero adotolo adandipangira ine analogue ndi kipimo chowonjezera cha Prolong ya misempha. Chifukwa chake, Glformin siili yoyenera kwa aliyense pothandizira odwala matenda ashuga.

Kupanga ndi mawonekedwe a kumasulidwa

Mankhwala amapitilira kugwiritsidwa ntchito ngati mapiritsi, omwe akhoza kukhala amitundu iwiri:

• Mapiritsi oyera a cylindrical okhala ndi chamfer yoyera (0,5 g yogwira ntchito). Zidutswa 10 zimayikidwa m'matumba am'manja.
• Mapiritsi mu kanema wa kirimu wa kirimu (0,85 kapena 1 g yogwira ntchito). Zidutswa 60 zimayikidwa mu zitini za polypropylene.

Zomwe zimagwiritsidwa ntchito ndi metformin hydrochloride.

Zotsatira za pharmacological

Glyformin ya matenda ashuga iyenera kumwedwa kokha pakamwa. Kapangidwe ka mankhwala pamakina a ziwalo zamkati sikumveka bwino.

Zilowa mthupi, chinthu chogwira ntchito chimakhala ndi zotsatirazi:

• Kuponderezedwa kwa mapangidwe a mamolekyulu a shuga m'magazi.
• Kukhazikitsa kwa kuwonongedwa kwa chakudya chamoto.
• Kuchepetsa kuchuluka kwa shuga m'matumbo.

Kugwiritsa ntchito mankhwalawa "Glyformin" odwala matenda ashuga komanso kunenepa kwambiri kumapangitsa kuchepa kwa chikhumbo ndi thupi. Malangizowo akuwonetsa kuti mankhwalawa amalimbikitsa kusinthasintha pang'onopang'ono kwa kuwundana kwa magazi ndikuletsa kupendekera.

Metformin hydrochloride imalowa mwachangu ndi maselo am'mimba. Pazitali zantchito yogwira ntchito imakhazikika pambuyo pa maola awiri kuchokera panthawiyi. Yake bioavailability pafupifupi 50-60%. Mankhwalawa samakumana ndi mapuloteni a plasma, pang'onopang'ono amadziunjikira machitidwe a ziwalo zamkati. Kuchokera mthupi, thupilo limachotsedwako pafupifupi osasinthika.

Zisonyezero zakugwiritsa ntchito mankhwala "Glformin"

Mapiritsi ogwiritsira ntchito amalimbikitsa kutenga odwala omwe ali ndi ma pathologies otsatirawa:

• Type II shuga mellitus, pamene mankhwala othandizira pakudya ndi sulfonylurea kukonzekera sikugwira ntchito.
• Mtundu woyamba wa matenda a shuga a mellitus (kuwonjezera pa mankhwala a insulin).

Mankhwalawa, kuyang'anira impso ndikofunikira, kamodzi miyezi isanu ndi umodzi ndikulimbikitsidwa kuti muwone lactate m'magazi a magazi.

Kuyanjana kwa mankhwala osokoneza bongo

Malinga ndi malangizo, kugwiritsa ntchito nthawi imodzi ndi insulin, mankhwala osapweteka a antiidal, sulfonylureas, beta-blockers, kuchuluka kwa Glyformin sikuwonetsedwa.

Kuchita kwake kumatha kuchepa motsutsana ndi maziko a chithandizo chowonjezera ndi glucocorticosteroids, kulera kwapakamwa, mahomoni a chithokomiro, zotumphukira za nicotinic acid.

Mtengo ndi malo osungira

Mankhwalawa amayenera kusungidwa kutentha mpaka madigiri 25 pamalo otetezedwa kwa ana. Moyo wa alumali ndi zaka zitatu, ndipo mapiritsi azovala za filimu - zaka ziwiri.

Kodi ndalama zikufanana ndi chiyani? Mu matenda ashuga, mtengo wa mankhwala umagwira gawo lofunikira kwa odwala ambiri. Mankhwala omwe afotokozedwa m'nkhaniyi ndi otsika mtengo. Poika mapiritsi m'mapulogalamu amaola ayenera kulipira ndalama zopitilira 300 ma ruble. Mapiritsi okhala ndi chamfer olekanitsidwa (0,5 g yogwira ntchito) ndiotsika mtengo - pafupifupi ma ruble 150.

Mankhwala "Glyformin" akagulidwa, gwiritsani ntchito, malangizo, onani - ichi ndi chinthu choyamba chomwe odwala amalabadira. Chifukwa chazinthu zingapo zotsutsana, mankhwala sakhala oyenera ambiri. Mutha kusankha mankhwalawa ofanana ndi mankhwalawa atatha kufunsa dokotala.

Pakati pazofanizira zomwe zimagwirizana kwambiri ndi Glformin malinga ndi zomwe zili pazomwe zimagwira, zotsatirazi ndizosiyanitsidwa: Diaberite, Metformin, Glucoran.

Ndemanga za odwala ndi madokotala

Odwala ambiri omwe amadziwika kuti amamwa mankhwalawa amauza munthu wina kuti ali ndi bongo wambiri. Nthawi zambiri, zimachitika chifukwa chogwiritsa ntchito mankhwalawa mosayenera. Mankhwala osokoneza bongo amatha kuyambitsa kupezeka kwa lactic acidosis. Zizindikiro zake zazikulu ndi: kupweteka kwa minofu, kusanza ndi mseru, kusokonezeka kwa chikumbumtima. Ngati wodwalayo ali ndi zizindikilo zotere, ndikulimbikitsidwa kusiya kumwa mankhwalawa ndikupempha thandizo kwa dokotala.

Kumbali ya akatswiri, ndemanga zambiri zimakhala zabwino. Ichi ndichifukwa chake Glyformin nthawi zambiri amalembera odwala matenda ashuga. Mtengo wa mankhwalawo ndi wotsika, ukhoza kugulidwa pa mankhwala aliwonse. Mukamatsatira malangizo mosamala, mwayi wokhala ndi zotsatirapo zake ndizochepa. Madokotala amachenjeza kuti munthawi yonse ya chithandizo ndikofunikira kuyesedwa kwa serum creatinine katatu pachaka. Pa mankhwala, mowa ndi mankhwala okhala ndi Mowa zimayenera kutayidwa.

Mwachidule

Matenda a shuga ndi matenda ofala, omwe masiku ano akupezekanso kwambiri kwa achinyamata. Chithandizo chake, madokotala amatipatsa mankhwala osiyanasiyana. "Glyformin" amatanthauzanso iwo. Awa ndi mankhwala a hypoglycemic omwe amachititsa kuti khungu lizilimbitsa thupi. Ngati mukumvera malingana ndi malangizo komanso monga momwe dokotala wakupangirirani, payenera kukhala mavuto ena. M'pofunikanso kuganizira za zotsutsana za mankhwalawa.