Maninil kapena metformin ndiyabwino

Chithandizo cha matenda a shuga ndi amitundu iwiri: jakisoni wa insulin komanso kugwiritsa ntchito mankhwala ochepetsa shuga.

Kusankha kwotsirizira kumayendetsedwa ndi zovuta: kusankha mankhwala ndi kwamodzi payekha, muyenera kuganizira kuchuluka kwa kubwezeredwa.

Madokotala nthawi zambiri amapereka mapiritsi ofanana ndi odwala, kotero kwa odwala matenda ashuga ndikofunikira kudziwa kuti ndibwino - Metformin kapena Diabeteson.

Makalata ochokera kwa Owerenga

Agogo anga akhala akudwala matenda a shuga kwa nthawi yayitali (mtundu 2), koma posachedwapa mavuto atuluka pamiyendo ndi ziwalo zamkati.

Mwangozi ndidapeza nkhani pa intaneti yomwe idapulumutsa moyo wanga. Ndidalumikizidwa kumeneko kwaulere pafoni ndipo ndidayankha mafunso onse, ndikuuzidwa momwe ndingachitire ndi matenda ashuga.

Patatha milungu iwiri atatha kulandira chithandizo, agogo aja adasinthiratu momwe akumvera. Ananenanso kuti miyendo yake sikupweteka komanso zilonda zake sizinayende; sabata yamawa tidzapita ku ofesi ya dotolo. Falitsa ulalo wa nkhaniyo

Kusiyana kwakukulu pakati pa mankhwala osokoneza bongo

Mu matenda a shuga, mankhwala a hypoglycemic amaperekedwa, zochita zomwe zimayendera limodzi. Komabe, odwala ambiri amazindikira kuti pakapita nthawi, mphamvu ya mankhwalawo imafooka - dokotala amakakamizidwa kuti apereke mapiritsi ofananawo. Komanso, m'malo mwake mumachitika chifukwa chakubala - Zizindikiro za matenda ashuga zimakulitsidwa. Metformin ndi Diabeteson amadziwika ndi ambiri omwe ali ndi matenda ashuga, ndipo pali zifukwa zomveka zotithandizira.

Malinga ndi momwe mungagwiritsire ntchito, ndikwabwino kuti munthu amwe shuga - limodzi piritsi limodzi nthawi imodzi mukatha kudya. Dongosolo loterolo limalola anthu omwe ali ndi gawo lotanganidwa kuti aziyang'anira thanzi lawo osataya nthawi. Metformin amawonetsedwa mpaka katatu patsiku chakudya kapena chakudya.

Malinga ndi momwe amagwirira ntchito, mapiritsiwa ndi osiyana kwambiri, ngakhale kuti mankhwalawa onse amitundu iwiri ya shuga amagwiritsidwa ntchito. Chofunikira chachikulu cha Diabeteson ndi gliclazide, yomwe imathandizira katulutsidwe ka insulin. Zotsatira zake, kuchuluka kwa shuga kumachepa pang'onopang'ono, osati spasmodically, komwe kumakupatsani mwayi wophatikiza zotsatirazo. Nthawi zambiri, madokotala amawalemba pambuyo poyesera kuti atenge Metformin.

Chimodzi mwa zinthu zomalizachi ndikutha kutsitsa shuga wamagazi popanda kuwonjezera kuchuluka kwa insulin. Cholinga chake ndikuthandizira kuchepetsa kufalikira kwa shuga ndi chiwindi ndikuchepetsa kuyamwa kwake ndi matumbo. Bhonasi yabwino ndiyothandiza pakumuka kwa mitsempha yamagazi komanso kunenepa kwambiri.

Mtengo wa mapiritsiwa umasiyana kwambiri: mtengo wa Metformin sapitilira ma ruble 200, ndipo wopikisana naye - ruble 350. Malire omwe akuwonetsedwa amafanana ndi mitengo yamapiritsi 30.

Ubwino wa Metformin

Mankhwala amatengedwa ngati ofunikira polimbana ndi matenda ashuga chifukwa cha katundu wambiri:

• Kuopsa kwa hypoglycemia ndikocheperako, pomwe insulin kapena mankhwala ena angayambitse izi. Hypoglycemic coma ndi chiopsezo cha thupi.
• Osapindulitsa kulemera. Popeza kuti kunenepa kwambiri kumawerengedwa kuti ndi chifukwa chachikulu chokonzera matenda amtundu wa 2, izi zitha kuonedwa ngati kuphatikiza kwakukulu.
• Zimasintha mayamwidwe achilengedwe a glucose, ndipo sizimachepetsa shuga chifukwa chazinthu zowonjezera pa kapamba.
• Zothandiza pa mtima dongosolo, amachepetsa chiopsezo magazi kuundana.

Zomwe zalembedwazi zimatsimikiziridwa ndi mayeso angapo azachipatala m'zaka zapitazi. Metformin imachepetsa chiopsezo cha kufa chifukwa cha zovuta za shuga ndi pafupifupi 50%. Pali zotsatira zoyeseza zomwe zimanena kuti mapiritsiwa amalepheretsa chitukuko chamatendawa kukhala osadwala matenda ashuga ndi 30%.

Komabe, mankhwalawa sikuti ndi vuto la anthu odwala matenda ashuga, kusintha kwa mtima, mwachitsanzo, sikwabwino kuposa insulin. Kutsutsana kwa asayansi pazabwino za mankhwalawa sikunathebe mpaka pano, koma chinthu chimodzi ndichotsimikizika - Metformin imathandizadi odwala matenda ashuga.

Kuzindikira kwa shuga - ingomwani tsiku lililonse.

Phindu la Diabetes

Mankhwalawa adadziwika chifukwa chogwira ntchito kwambiri komanso zotsatira zazitali. Posachedwa, pali mankhwala ofanana "Diabeteson MV" omwe amagwiritsidwanso ntchito ngati piritsi limodzi patsiku.

Ubwino wofunikira ndikuti kugwiritsa ntchito prophylactic - kupewa nephropathy (gawo lachiwiri la gestosis mwa amayi apakati), stroko ndi myocardial infarction.

Kafukufuku wambiri awonetsa kuti njira yotenga Diabeteson imabwezeretsa gawo loyamba la insulin, kupindulitsa bwino glycemia. Izi zimakuthandizani kuti muthe kusintha ntchito ya thupi, komanso osachulukitsa katunduyo.

Kulemera kwa thupi sikukula ngakhale mutatha kumwa mapiritsi awa kwa nthawi yayitali, kumakulitsa mkhalidwe wamakoma amtima. Odwala omwe ali ndi matenda ashuga, kuchuluka kwa ma radicals kumawonjezereka, izi zingayambitse khansa. Diabetes ndi mtundu wa antioxidant, chifukwa chake imayimitsa chiwopsezo ichi pamlingo wina ndipo imateteza ku nkhawa za oxidative. Kuphatikiza pa izi, kumwa mankhwalawa kumathandizanso kuti mawonekedwe ang'onoang'ono.

Kulandila kwa Metformin ndi Diabeteson

Kuti mumvetsetse ngati Diabeteson ndi Metformin atha kukhala limodzi, muyenera kumvetsetsa zovuta zawo. Njirayi imakhala yovuta ndi zovuta komanso zovuta kudziwa kulosera za matendawa. Dokotala wokhayo amene angakupatseni mankhwala omwe amakupatsirana munthawi yomweyo.

Kuphatikizidwa kwa Metformin ndi Diabetes ndi imodzi mwazomwe zimalembedwa, ndipo izi zimafotokozedwa mosavuta ndi zomwe amachita. Loyamba likufuna kukonza kusokonezeka kwachilengedwe kwa shuga, ndipo chachiwiri - pakuwonjezera katulutsidwe ka insulin m'madzi am'magazi. Onse awiriwa samatsogolera kunenepa kwambiri (komwe kumachitika mu shuga) ndipo amathandizana wina ndi mnzake.

Kumbukirani kuti mankhwalawa ali ndi mtundu wina wa mankhwala, kulakwitsa kumayambitsa vuto la glycemic. M'masiku oyamba ovomerezeka, mpaka chizolowezi chizindikira, ndikofunikira kuwunika mosamala kutsatira.

Metformin imalembedwa matenda ena malinga ndi gynecology, ndipo Diabetes amakhala bwino mthupi - katundu wake monga antioxidant adanenedwa pamwambapa. Kuyendetsa ntchito limodzi kudzachepetsa kuvutikako chifukwa cha matenda ashuga, zomwe zikukhudza chiwongola dzanja chambiri.

Mankhwalawa onse amavomerezedwa kuti agwiritsidwe ntchito motsutsana ndi matenda amtundu wa 2 wokha, sagwirizana ndi jakisoni wa insulin. Yankho lenileni la funso loti muthe kutenga diabeteson ndi Metformin nthawi yomweyo, ndikofunikira kuti muzidziwitsa zolakwika zilizonse zomwe mankhwala amapanga. Ndi mgwirizano wophatikizidwa, m'modzi yekha ndiamene angayambitse zoyipa, monga lamulo, vutoli limathetsedwa ndikusintha mankhwalawa ndi linzake.

Contraindication

Kuvuta posankha mankhwala oyenera a shuga kumayambira mu dalili yayikulu yomwe imakhudza machitidwe ambiri amthupi. Chifukwa chake, ndikosavuta kupangitsa gawo loyipa la matenda ndi mankhwala atsopano. Chifukwa chake, ngati zotsatira zoyipa zikuchitika, muyenera kufunsa dokotala. Popewa zinthu zovuta, ndikofunikira kuyendera ma contraindication.

Timapereka kuchotsera kwa owerenga tsamba lathu!

Diabetes amakhala ndi zotsutsana zambiri, chimodzi mwazofunikira komanso zovuta ndi kukalamba. Mukadwala wodwala wazaka zopitilira 65, mkhalidwe wakewo umachepa - kagayidwe kachakudya kamachepa pazifukwa zachilengedwe. Izi zikugwiranso ntchito ku matenda angapo:

Diabeteson MV imalekananso ndi ana osakwana zaka 18, amayi oyamwitsa ndi amayi apakati. Anthu odwala matenda a shuga omwe amadalira insulin sayeneranso kugwiritsa ntchito mankhwalawa, mgwirizano ndi Miconazole ndi woletsedwa.

Mndandanda wa contraindication wa Metformin siwokulira, umaphatikizapo matenda omwe ali pachimake. Siligwiritsidwanso ntchito ngati matenda a impso ndi chiwindi, atatha kulowetsedwa ndi magazi m'thupi. Kuchita opweteka kwambiri komanso kuvulala, uchidakwa wopitilira muyeso.

Ketoocytosis, ngakhale kukhalapo kwa chikomokere, sizigwirizana ndi kumwa mapiritsi awa. Izi zimagwiranso ndi metabolic acytosis.

Pa nthawi yoyembekezera komanso mkaka wa m'mawere, imagwiritsidwa ntchito pokhapokha ngati mayeserowo agwiritsidwa ntchito ndikofunika kwambiri kuposa chiwopsezo cha mwana wosabadwayo. Nthawi zadzidzidzi zotere zimachitika ndi nephropathy komanso matenda a shuga.

Zoletsa pakugwiritsa ntchito Metformin ndi ana ndi okalamba (palibe maphunziro omwe adachitidwa). Mukugwira ntchito zolimbitsa thupi, ndikosavuta kuneneratu za kuyamwa kwa glucose.

Madokotala akhala akufufuza zamankhwala amshuga mzaka zambiri, akusintha kuwunika kwawo iliyonse. Mankhwala onsewa adayesedwa kangapo, ndipo mpaka pano mapiritsi omwe amagwiritsidwa ntchito kwambiri ndi kuchepetsa shuga.

Matenda a shuga nthawi zonse amayambitsa zovuta zakupha. Mwazi wamagazi ochulukirapo ndi woopsa kwambiri.

Aronova S.M. adafotokoza za chithandizo cha matenda ashuga. Werengani kwathunthu

Zotsatira za pharmacological

Mfundo za Metformin ndikupewa gluconeogeneis. Zinthu zimayambitsa enzyme yapadera m'chiwindi chomwe chimalepheretsa kulowa kwina kwa glucose kulowa m'magazi. Mankhwalawa amalepheretsa kusintha kwamafuta acids ndikulimbikitsa kukhatikiza kwawo, kumalepheretsa mayamwidwe a shuga m'matumbo.

Poyerekeza ndi ena othandizira a hypoglycemic, mankhwalawa amathandiza kwambiri kupewa matenda a matenda a shuga. Pogwiritsa ntchito mwadongosolo, mankhwalawa amalepheretsa kulemera, ndipo pakudya, amathandizira kuchepetsa.

Mankhwala amalepheretsa kukula kwa insulin ndipo amathandizira kulowa kwa shuga m'magazi a anthu. Ndi kuchepa kwa insulin m'mwazi, chinthucho sikuwonetsa katundu wa hypoglycemic.

Mankhwalawa amatha kuwonjezera mayankho a metabolic ku mahomoni, amachepetsa chiopsezo cha nephropathy komanso kufa. Mphamvu yamapangidwe sikugwirizana ndi kuchuluka kwa shuga m'magazi, motero mankhwalawa amagwira ntchito ngakhale ndi standardoglycemia.

Metformin imasankhidwa ngati othandizira matenda a shuga.

Mu matenda 1 a matenda ashuga, mankhwala atha kutumikiridwa ngati njira yolepheretsa kukula kwa matenda a shuga.

Mankhwala a Hypoglycemic amatha kugwiritsidwa ntchito ngati polycystic ovary, ngati kulolerana kwa hyperinsulinemia ndi glucose kumayang'aniridwa.

Glibenclamide imagwiritsidwa ntchito kokha mtundu wa 2 shuga mellitus, mukamagwiritsa ntchito zakudya zoyenera komanso katundu wokwanira sizotheka kuchepetsa shuga.

Kodi ndingatenge limodzi?

Kuchulukitsa kwa shuga kwa glibenclamide kumadalira mlingo: wokulirapo, umakhudzidwa kwambiri ndi kapamba.

Mukakhudzidwa ndi chinthu chogwira ntchito, insulin yowonjezera imayamba kupanga, chifukwa chake kusankha kwa Maninil kofunikira kumatsimikiziridwa ndi shuga.

Popereka mankhwala, dokotala nthawi zonse amapereka malangizo pazakudya ndikuganizira kuchuluka kwa chakudya chamagulu muzakudya. Pa gawo loyambirira, chithandizo chimayamba ndi mlingo wotsika kwambiri, ndipo pambuyo pa makonzedwe, zovuta za matenda ashuga zimawonedwa.

Ngati ndi kotheka, onjezerani kuchuluka kwa mankhwalawo. Imwani mankhwalawa 1-2 kawiri pa tsiku, zomwe zimapangitsa kuti pakhale mankhwala osachepera maola 12.

Kuti muwonjezere kuchuluka kwa hypoglycemic ndikuchepetsa kudya kwa magazi m'magazi, makuponi a Maninil omwe ali ndi Metformin amatha.

Kuphatikiza kwa mankhwalawa kumagwiritsidwa ntchito pomwe sikungatheke kukwaniritsa zofunikira zochizira.

Mankhwala owonjezera a antiidiabetes amafunsidwa ndi dokotala. Kuphatikiza ndi mankhwala ena, mphamvu ya glibenclamide m'thupi imalimbikitsidwa.

Mukamapereka mankhwala othandizira a hypoglycemic, amawongoleredwa ndi kufunika kochizira, momwe amagwirira ntchito pazinthu zomwe zikuchitika, zotsutsana zomwe zikugwiritsidwa ntchito pakalipano.

Metformin kapena Maninil

Chizindikiro cha Metformin ndikuti kuchuluka kwa hypoglycemic pa thupi sikukhudzana ndi kuchuluka kwa insulin. Mfundo ya mankhwalawa ndi kupinikiza njira zomwe glucose amatenga.

Metformin ndi amodzi mwa mankhwala ochepa omwe chiopsezo chotenga hypoglycemia ndi ochepa. Kuphatikiza pa maonekedwe a matumbo, mankhwalawa alibe zotsatira zoyipa. Lactic acidosis imatha kuchitika ndi bongo wambiri komanso vuto la impso.

Chifukwa chake, pakupanga kwachilendo kwa mahomoni a peptide ndi kapamba, koma ndikulimbana kwambiri ndi insulin, Metformin ndiyabwino.

Zoyipa zake ndi monga kuti greatuanide sangathe kuchepetsa shuga ndikusowa kwa insulin mthupi. Kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumalepheretsa mayamwidwe a vitamini B12, omwe pambuyo pake amatha kuyambitsa kukula kwa myalgia ndi magazi.

Glibenclamide ndi mankhwala okhawo a 2 a matenda ashuga, pomwe mapiritsi ena ochepetsa shuga sikokwanira.

Sulfonylurea derivative (glibenclamide) imakhala ndi zoyipa zingapo:

• ngati kuchuluka kwa zomwe zimagwiritsidwa ntchito kwadutsa, hypoglycemia imayamba,
• kunenepa
• kupweteka kwa molumikizana
• mutu
• chidwi chachikulu pakuwala,
• malungo
• kudzimbidwa,
• kutopa kwambiri
• proteinuria (mapuloteni amawoneka mkodzo),
• cholestatic syndrome
• thupi lawo siligwirizana
• kukodza pafupipafupi.

Mndandanda wa zotsutsana ndi mankhwala ndizofanana, kupatula kuti glibenclamide ndizoletsedwa kutenga ndi shuga yodalira insulin.

Metformin, Maninil sangathe kugwiritsidwa ntchito pazinthu izi:

• wodwala matenda ashuga
• mimba
• kuyamwa
• kuphwanya chiwindi ndi impso,
• mawonekedwe a ketoacidosis,
• Hypersensitivity.

Glibenclamide itha kugwiritsidwa ntchito mosamala mu zakumwa zoledzeretsa, zomwe kwa greatuanide ndizolepheretsa.

Kuphatikiza apo, Metformin idathetsedwa masiku awiri asanafike komanso pambuyo pa x-ray, ngati pakadakhala poyambitsa kusiyana.

Maninil kapena Amaryl

Amaryl ndi othandizira a hypoglycemic kutengera zochokera ku sulfonylurea zochokera m'badwo wachitatu. Muli yogwira pophika - glimepiride. Mfundo yakuchitapo kanthu ndikulimbikitsa kumasulidwa kwa insulin ya insulin ndi kapamba.

Mosiyana ndi Maninil, Amaryl ali ndi zina zowonjezera - mankhwalawa amaponderera gluconeogeneis. Mphamvu ya hypoglycemic ya Amaril imatchulidwa kwambiri ndipo ndi maola osachepera 24.

Maninil ndi Amaril sangathe kulembedwa mtundu wa shuga wodalira insulin. Mukamasankha mtundu wa Amaril ndi chithandizo chotsatira, kuwerenga kwa shuga kwa magazi kuyenera kukumbukiridwa, chifukwa pali mwayi wopanga hypoglycemia.

Mawonekedwe olakwika ogwiritsa ntchito mankhwala ndi contraindication sikuti ndi osiyana. Kupatula ndi vuto logaya chakudya mu Amaril, lomwe limalumikizidwa ndi njira yoletsa gluconeogenesis ndi mankhwalawa.

Makanema okhudzana nawo

Makina a kuchitapo kanthu, mawonekedwe amamasulidwe ndi zovuta zina zogwiritsira ntchito Metformin mu kanema:

Maninil ndi Amaryl ali ndi mphamvu yotsitsa shuga, koma amakhala ndi mndandanda wazotsatira zoyipa. Ngati kukondoweza kwowonjezera kwa pancreatic sikufunika pakupanga insulin,

Metformin ili ndi mwayi woonekeratu. Kukula kwakukulu kumachepetsa chiopsezo cha atherosulinosis, sikuti kumabweretsa kulemera ndikulepheretsa kukula kwa matenda a mtima.Zotsatira zoyipa zamagetsi zomwe zimachitika chifukwa cha kutenga biguanide zimadutsa mofulumira.

• Imakhazikika pamisempha ya shuga kwa nthawi yayitali
• Imabwezeretsa kapangidwe ka insulin

Phunzirani zambiri. Osati mankhwala. ->

Kodi milandu contraindication zotchulidwa

Kamodzi m'thupi la wodwalayo, mankhwalawa "Maninil" (mawonekedwe ake amatha kuchita mosiyana) amawonjezera chidwi cha insulin receptors. Ili ndi mphamvu yogwira mankhwalawa komanso zotsatira zina zabwino mthupi la wodwalayo. Maninil, mwa zinthu zina, amatha kulimbikitsa kupanga insulin.

Zisonyezo zogwiritsa ntchito mankhwalawa ndi mtundu 2 shuga. Mankhwalawa amatha kuperekedwa ndi endocrinologist. Zoyipa zomwe zimagwiritsidwa ntchito ndi:

mtundu 1 shuga

matenda a shuga

Mimba ndi kuyamwa

kupweteka kwambiri kwaimpso kapena chiwindi,

Kuchepetsa kuchuluka kwa maselo oyera.

Momwe mungagwiritsire ntchito

Mapiritsi 5 mg ali chimodzimodzi ndi mankhwalawa "Manin 3.5", malangizo ogwiritsira ntchito. Mtengo (analogies ya mankhwalawo ukhoza kukhala ndi mtengo wosiyana) mankhwalawa, monga tafotokozera kale, ndiokwera kwambiri. Kuphatikiza apo, madotolo amauza odwala kwaulere, mosiyana ndi otchipa otchipa, kawirikawiri. Ichi ndichifukwa chake odwala ambiri amakonda kudziwa ngati mankhwalawa ali ndi ma analogues otsika mtengo. Mankhwalawa amapezeka m'mafakitore. Koma tisanapitilize kufotokoza kwawo, tiwona malangizo ati omwe angagwiritsidwe ntchito ndi Manilin pachokha.

Dokotala amasankha muyeso wa mankhwalawa kwa wodwala payekha. Kuchuluka kwa mankhwalawa omwe amamwa patsiku kumadalira kuchuluka kwa shuga mumkodzo. Amayamba kumwa mankhwalawa nthawi zambiri ndi mlingo wochepera. Komanso, izi zimachulukirachulukira. Nthawi zambiri, poyambira, wodwalayo amapatsidwa theka la piritsi patsiku (kutengera zotsatira za kusanthula, 3.5 kapena 5 mg). Kenako, mlingo umakulitsidwa ndi osapitilira piritsi limodzi pa sabata kapena masiku angapo.

Ndemanga za "Maninil"

Ili ndi malangizo ogwiritsira ntchito mankhwalawa "Maninil". Makonda a mankhwalawa ndi ambiri. Koma "Maninil" odwala ambiri amawona mwina chida chabwino kwambiri pagulu lawo. Malingaliro a odwala omwe ali ndi matenda osokoneza bongo okhudzana ndi mankhwalawa adakula bwino. Zimathandiza, malinga ndi ogula ambiri, zabwino. Komabe, mwatsoka, mankhwalawa siabwino kwa onse odwala. Sikuti amapita kwa odwala ena.

Mulimonsemo, kupatula, odwala amalimbikitsa kumwa mankhwalawa kokha pa mlingo womwe adokotala amawalimbikitsa. Kupanda kutero, mankhwalawa angayambitse kuledzera.

Kodi ma fanizo a mankhwalawa "Manin" ndi ati?

Pali malo ena othandizira mankhwalawa pamsika wamakono. Ena a iwo apeza ndemanga zabwino za ogula, pomwe ena sanatero.

Nthawi zambiri, anthu odwala matenda ashuga amagwiritsa ntchito maimelo m'malo mwa "Maninil":

Nthawi zina odwala amakhala ndi chidwi chofuna kudziwa ngati pali analogue ya Manil 3.5 mg (mapiritsi) pamsika. Palibenso kufanana kwa mankhwalawa pamsika wamakono wamankhwala. Ma analogues ambiri amapangidwa pamaziko a zinthu zina zomwe zimagwira. Chifukwa chake, kuchuluka kwa mapangidwe omwe amapezeka m'mapiritsi olowa m'malo ndi kosiyana. Analogue yokhayo ya Maninil ndi Glibenclamide. Izi zokhazo zomwe zitha kugulidwa mu mlingo wa 3.5 mg.

Mankhwala "Glibenclamide"

Zizindikiro ndi zotsutsana za mankhwalawa ndizofanana ndendende ndi "Maninil" yomwe. Kupatula apo, kwenikweni, mankhwalawa ndi generic wake wotsika mtengo. Mankhwalawa ndi ofunika mumafakisi pafupifupi 80-90 p. Ngakhale zinthu zomwe zimagwiritsidwa ntchito ndizofanana kwa onsewa mankhwalawa, kuchotsa Maninil ndi Glibenclamide ndikololedwa kokha pazovomerezeka za dokotala. Matenda a shuga ndi matenda oopsa. Mankhwalawa amapangidwa ku Ukraine.

Maganizo a Odwala ku Glibenclamide

Monga Maninil, ndemanga (zoyerekeza za mankhwalawa ndi zinthu zina zogwira ntchito kwa odwala nthawi zambiri zimayipa), mankhwalawa kuchokera kwa ogula apeza zabwino. Kuphatikiza pakuchita bwino, machitidwe a zabwino za mankhwalawa, odwala ambiri amati mtengo wake wotsika komanso zovuta kugawa mapiritsi. Odwala ambiri amaganiza kuti mankhwala a Glibenclamide opangidwa ku Kiev ndi apamwamba kwambiri. Mapiritsi a Kharkov panthawi yogawa, mwatsoka, amatha kutha.

Mankhwala "Diabeteson"

Mankhwalawa amapezeka mu mawonekedwe a mapiritsi oyera ozungulira. Chofunikira chake chachikulu ndi glycoside. Monga Maninil, Diabetes ndi m'gulu la zinthu zotsitsa shuga za m'badwo wotsiriza. Ubwino wawukulu wa mankhwalawa ndi, kuwonjezera pa kugwira ntchito, kusapezeka kwa mankhwala osokoneza bongo. Mosiyana ndi Maninil, Diabetes imakulolani kuti mubwezeretse nsonga zoyambirira ndikulepheretsa kukula kwa hyperinsulinemia. Ubwino wa chida ichi, poyerekeza ndi mankhwala ena ambiri a gululi, ndikuphatikiza kuti imatha kutsitsa cholesterol yamagazi.

Ndemanga pa "Diabeteson"

Kuchuluka kwa shuga m'magazi, malinga ndi odwala ambiri, mankhwalawa amathandizanso kwambiri. Zotsatira zoyipa, malinga ndi ogula, "Diabeton" imapereka kawirikawiri. Odwala ambiri amati zovuta za mankhwalawa makamaka ndimtengo wake wokwera mtengo. Muyenera kulipira zochulukirapo kuposa Maninil. Analogs (mtengo wa mankhwala omwe amagwiritsidwa ntchito popanga matenda ashuga amatha kukhala osiyanasiyana) wa mankhwalawa nthawi zambiri amakhala wotsika mtengo. Matenda a shuga ndi osiyana ndi ena pankhaniyi. Pali phukusi la mapiritsi 60 a chinthu ichi m'mafakitala a 300 r. Mankhwalawa ndi oyenera, monga mankhwala ambiri ochepetsa shuga, mwatsoka, osati kwa odwala onse.

Mankhwala "Metformin"

Mankhwalawa amapezekanso m'mapiritsi ndi ma pharmacies ndi zipatala. Chofunikira chake chachikulu ndi metformin hydrochloride. Kupanga kwamankhwala kwa wothandizirayo kumawonekera makamaka chifukwa kumachepetsa kuchuluka kwa shuga m'matumbo. Sapereka mphamvu iliyonse popanga insulin, monga Glibenclamide ndi Maninil. Chimodzi mwamaubwino osakayikitsa a mankhwalawa ndikuti samayambitsa maonekedwe a hypoglycemia m'thupi.

Ndemanga za Metformin

Odwala amatamanda mankhwalawa makamaka chifukwa chofatsa. Metformin yatulutsa ndemanga zabwino komanso chifukwa chakugwiritsa ntchito ndizotheka osati kungochiza matenda ashuga. Chimalimbikitsa kugwiritsa ntchito mankhwalawa komanso kuchepetsa kulemera kwa odwala. Monga Diabeteson, mankhwalawa, mwa zina, amachepetsa mafuta m'thupi m'magazi a odwala. Kuphatikiza kwa malonda ena kumawonekeranso mtengo wotsika kwambiri: mapiritsi 60 a Metformin amatenga pafupifupi 90 r.

Zina mwa zovuta za mankhwalawa, ogula amangoganiza kuti m'miyezi yoyamba kumwa, zimatha kuyambitsa matenda otsegula m'mimba. Zotsatira zoyipa zoterezi nthawi zina zimaperekedwa ndi Maninil palokha. Ma analogi ake nthawi zambiri amakhalanso osiyana mumtundu womwewo. Koma mavuto am'mimba mwa ambiri mwa mankhwalawa nthawi zambiri samatchulidwa.

Mankhwala "Glimepiride" ("Amaril")

Mankhwalawa amapangidwa pamaziko a chinthu chotchedwa glimepiride. Zimakhala ndi zovuta m'thupi la wodwalayo - zimapangitsa kuti pakhale zofunikira, zimalepheretsa kupanga shuga m'chiwindi, komanso zimapangitsa chidwi cha minofu kugwira ntchito ya mahomoni. Mankhwalawa amachepetsa kwambiri mwayi wokhala ndi matenda a shuga. Nthawi zambiri, Amaril amatchulidwa ndi madokotala nthawi yomweyo ngati Metformin. Kugulitsa lero palinso mankhwala, omwe ndi zovuta pazinthu zonse zomwe zimagwira. Amatchedwa Amaril M.

Ndemanga za Mankhwala

Malingaliro okhudzana ndi mankhwalawa kwa anthu odwala matenda ashuga ndi abwino kwambiri. Zomwe zimagwiritsidwa ntchito nthawi zambiri zimadziwika. Amakhulupirira kuti kugwiritsa ntchito mankhwalawa ndikwabwino ngati Metformin yokha siyithandiza. Makulidwe a mapiritsi a Amarin ndi akulu. Kuphatikiza apo, ali ndi chiopsezo. Chifukwa chake, kuwagawana ngati kuli kofunikira ndi kosavuta kwambiri.

Mankhwala "Glucophage"

Mankhwalawa amagwirizana ndi Metformin. Zomwe zimagwiritsidwa ntchito ndizofanana kwa iye. Zomwezo zimapita kuzisonyezo ndi ma contraindication. Monga Metformin, mankhwalawa amathandizanso thupi la wodwalayo. Amachepetsa kulemeranso bwino.

Ndemanga za mankhwalawa ndizofanana ndendende ndi Metformin. Odwala ena amakhulupirira kuti awa ndi amodzi amodzi mankhwala, koma kuchokera kwa opanga osiyanasiyana.

M'malo momaliza

Chifukwa chake, tidazindikira chomwe "Maninil" ndi (malangizo ogwiritsira ntchito, mtengo, analogues tsopano akukudziwani). Mankhwalawa, monga mukuwonera, ndi othandiza. Ambiri omwe amagwirizana nawo amayenera kuwunikiridwa bwino kwambiri kuchokera kwa odwala. Komabe, ndikofunikira kugwiritsa ntchito mankhwalawa ndikusintha ndi mankhwala ena omwe ali ndi zofanana zochizira, zofunikira, pokhapokha ngati adokotala akuwalimbikitsa.

Mawonekedwe a Diabetes

Choyamba, ndikufuna kukhala pa Diabeteson, yomwe imagwiritsidwa ntchito pa matenda a shuga a 2. Chida ichi ndi chabwino chifukwa chimathandizira kupanga insulini, komanso imathandizira kuchuluka kwa zimakhala. Kuphatikiza apo, mankhwala omwe aperekedwa amakupatsani mwayi wochepetsera nthawi yakudya chakudya kuti mupange insulin. Palibe mawonekedwe ofunika kwambiri omwe akuyenera kuwonedwa ngati kuchepa kwa cholesterol.

Ndizodziwikanso kuti pamaso pa nephropathy, mankhwalawa amathandizira kuchepetsa kuchuluka kwa proteinuria. M'milandu yambiri, chisankho chomaliza chogwiritsira ntchito ndalamazo chimatengedwa ndi akatswiri pokhapokha kuwunika konse kukamalizidwa. Mwambiri, odwala matenda ashuga amayesedwa ngati chida chomwe chimathandizira thupi. Komabe, alinso ndi zotsutsana zingapo zomwe zimayenera kuyang'aniridwa kuchokera kwa odwala matenda ashuga.

Ponena za malire, ndikofunikira kulabadira kupezeka kwa mtundu wa 1 shuga mellitus, chikomokere kapena precomatose state. Kuphatikiza apo, kuphwanya lamulo ndikuphwanya impso ndi chiwindi, komanso kuchuluka kwa chidwi cha zigawo zina monga sulfonamides ndi sulfonylurea. Ndi momwe aperekera matendawo, zovuta zonse zolimbitsa thupi zimayikidwa, komanso kutsatira zakudya zina.

Poona kuti izi sizipangitsa kuti azitha kuthana ndi matendawa, perekani mankhwala omwe amatchedwa Diabeteson.

Gliclazide, yomwe imaphatikizidwa mndandanda wake wazinthu, imalola ma cell a kancensa kuti apange insulin yambiri. Zotsatira zakugwiritsa ntchito gawo limayesedwa kwambiri ngati zili zabwino. Polankhula pazinthu zina, ndikofunikira kulabadira kuti:

1. Odwala amatengera kuchepa kwakukulu kwa zizindikiro zamagulu a shuga, pomwe mwayi wa hypoglycemia ndi wochepera 7%,
2. Ndiosavuta kugwiritsa ntchito mankhwala amenewa kamodzi patsiku, ndipo chifukwa chake odwala sakonda kusiya chithandizo chotere cha matendawa,
3. Zizindikiro zakulemera zimachulukanso, koma pang'ono, zomwe nthawi zambiri sizikhudza thanzi lawo.

Akatswiri amalimbikitsa kugwiritsa ntchito Diabeteson, chifukwa ndi yabwino kwambiri kwa odwala ndipo imalekerera popanda mavuto. Ambiri mwa odwala matenda ashuga sawona kukhala kosavuta kugwiritsa ntchito piritsi limodzi pakapita maola 24 aliwonse kuposa kungokhala ndi zochitika zolimbitsa thupi komanso kudya kwambiri. Akatswiri amadziwa kuti ndi 1% yokha ya odwala omwe adakumana ndi zodandaula zilizonse zomwe zimachitika, pomwe odwala omwe adatsala amawona bwino komanso samakumana ndi mavuto azaumoyo.

Contraindication adaziwona kale, koma tsopano ndikofunikira kuzindikira zolakwitsa zina za mankhwala. Choyamba, tikulankhula za momwe zimachitika pakufa kwa maselo a beta, omwe amaphatikizidwa ndi kapamba. Potere, mawonekedwe a pathological amatha kusintha kukhala mtundu woyamba wovuta. Gulu lamavuto limaperekedwa makamaka kwa anthu omwe ali ndi thupi loonda. Kusintha kwa gawo lovuta kwambiri la matendawa, nthawi zambiri, kumatenga zaka ziwiri mpaka zisanu ndi zitatu.

Mankhwalawa amachepetsa shuga, koma samachepetsa kufa. Ndikofunikira kutengera chidwi kuti akatswiri amapereka mankhwala a shuga, koma izi sizolondola. Kafukufuku wambiri akuwonetsa kuti ndikofunikira kuti ndiyambire ndi Metformin, yomwe idakhazikitsidwa pazomwe zimaphatikizidwa.

Mapangidwe monga Siofor, Glformin ndi Glyukofazh ali m'gulu lomweli.

Mawonekedwe a Manin

Maninil mapiritsi a shuga mellitus amatchulidwa kuti muchepetse magazi pamavuto amtundu wachiwiri wa matenda. Mankhwala amadziwika ndi pancreatic algorithm yowonekera, komanso amakupatsani mwayi wolimbikitsa maselo a beta okhudzana ndi kapamba. Kuphatikiza apo, ndiye gawo lomwe limaperekedwa lomwe limakulitsa chiwopsezo cha insulin receptors, chomwe ndichofunikira kwambiri mu matendawa komanso mthupi lonse.

Poyerekeza Maninil ndi Diabetes, ndikufuna ndikuwuzeni kuti mtundu 1 wa shuga ndiwopondanso kugwiritsa ntchito pamenepa. Kuphatikiza apo, akatswiri amapereka chidwi pakuwonjezereka kwa zinthu zina zapagulu. Tisaiwale za kuchotsedwa kwa kapamba, matenda a impso, komanso matenda a chiwindi. Kusagwirizana kofunikira kwambiri kuyenera kuganiziridwa nthawi yoyamba pambuyo pa opaleshoni yokhudzana ndi chiwalo chilichonse chamkati. Simalimbikitsidwa kugwiritsa ntchito mapangidwe anthawi zonse pamene muli ndi pakati, komanso mukamayamwitsa komanso m'matumbo.

Akatswiri akuwunika chidwi chakuti chipangidwe chamankhwala cha odwala matenda ashuga Maninil chimadziwika ndi zotsatira zoyipa zingapo. Polankhula za izi, akatswiri amalabadira kuthekera kwa hypoglycemia. Kuphatikiza apo, ndikulimbikitsidwa kuti muzisamaliranso mseru ndi kusanza, kuwonjezera kwa jaundice, hepatitis, zotupa pakhungu. Zotsatira zoyipa zingaphatikizepo kupweteka kwapakati komanso kuwonjezeka kwa kutentha kwa thupi.

Popeza zonsezi, ngati lingaliro lipangidwe kuti lisinthe mankhwala ena ndi mawonekedwe ake, ndikulimbikitsidwa kuti mukafunse katswiri. Adzakhala amene apanga pulogalamu inayake ya algorithm ndi mlingo wake.

Kuphatikiza apo, akatswiri akuwunikira kuti sulfonylureas amadziwika ndi vuto lalikulu poyerekeza ndi maubwino owonetsa thupi omwe ali ndi matenda omwe aperekedwa. Kusiyanitsa komwe kumatsimikiziridwa pakati pa Maninil ndi Diabeteson ndikuti gawo loyamba lazinthu zamankhwala limaganiziridwa ndikuzindikiridwa kwambiri.

Kuopsa kwa vuto la mtima, komanso matenda amtima kumaonjezereka kapena kuwonjezereka mukamagwiritsa ntchito mankhwalawa.

Kupereka chidziwitso chowonjezera pakuyerekeza kwa mankhwala aliwonse omwe aperekedwa, ndikofunikira kulabadira njira yomwe amasankha. Malinga ndi akatswiri, a shuga ndiwotsika mtengo masiku ano. Kuphatikiza apo, nthawi zambiri imasankhidwa chifukwa chothandiza kwambiri m'thupi la munthu. Mutha kugula ku malo ogulitsira, koma ndikulimbikitsidwa kuti mugwiritse ntchito ndendende kuchuluka komwe anakumana ndi katswiri wa matenda ashuga.

Zomwe zili bwino - manninil, shuga kapena metformin

Maninil mapiritsi a shuga mellitus amatchulidwa kuti muchepetse magazi pamavuto amtundu wachiwiri wa matenda. Mankhwala amadziwika ndi pancreatic algorithm yowonekera, komanso amakupatsani mwayi wolimbikitsa maselo a beta okhudzana ndi kapamba.

Poyerekeza Maninil ndi Diabetes, ndikufuna ndikuwuzeni kuti mtundu 1 wa shuga ndiwopondanso kugwiritsa ntchito pamenepa. Kuphatikiza apo, akatswiri amapereka chidwi pakuwonjezereka kwa zinthu zina zapagulu.

Tisaiwale za kuchotsedwa kwa kapamba, matenda a impso, komanso matenda a chiwindi. Kusagwirizana kofunikira kwambiri kuyenera kuganiziridwa nthawi yoyamba pambuyo pa opaleshoni yokhudzana ndi chiwalo chilichonse chamkati.

Akatswiri akuwunika chidwi chakuti chipangidwe chamankhwala cha odwala matenda ashuga Maninil chimadziwika ndi zotsatira zoyipa zingapo. Polankhula za izi, akatswiri amalabadira kuthekera kwa hypoglycemia.

Kuphatikiza apo, ndikulimbikitsidwa kuti muzisamaliranso mseru ndi kusanza, kuwonjezera kwa jaundice, hepatitis, zotupa pakhungu. Zotsatira zoyipa zingaphatikizepo kupweteka kwapakati komanso kuwonjezeka kwa kutentha kwa thupi.

Popeza zonsezi, ngati lingaliro lipangidwe kuti lisinthe mankhwala ena ndi mawonekedwe ake, ndikulimbikitsidwa kuti mukafunse katswiri. Adzakhala amene apanga pulogalamu inayake ya algorithm ndi mlingo wake.

Kuphatikiza apo, akatswiri akuwunikira kuti sulfonylureas amadziwika ndi vuto lalikulu poyerekeza ndi maubwino owonetsa thupi omwe ali ndi matenda omwe aperekedwa. Kusiyanitsa komwe kumatsimikiziridwa pakati pa Maninil ndi Diabeteson ndikuti gawo loyamba lazinthu zamankhwala limaganiziridwa ndikuzindikiridwa kwambiri.

Kuopsa kwa vuto la mtima, komanso matenda amtima kumaonjezereka kapena kuwonjezereka mukamagwiritsa ntchito mankhwalawa.

Kupereka chidziwitso chowonjezera pakuyerekeza kwa mankhwala aliwonse omwe aperekedwa, ndikofunikira kulabadira njira yomwe amasankha. Malinga ndi akatswiri, a shuga ndiwotsika mtengo masiku ano.

Kuphatikiza apo, nthawi zambiri imasankhidwa chifukwa chothandiza kwambiri m'thupi la munthu. Mutha kugula ku malo ogulitsira, koma ndikulimbikitsidwa kuti mugwiritse ntchito ndendende kuchuluka komwe anakumana ndi katswiri wa matenda ashuga.

Mankhwala monga Maninil ndi Diabeteson amachititsa kuthana ndi kuchuluka kwa shuga m'magazi. Komabe, kuwonjezera pa zabwino zake, chilichonse chomwe chaperekedwa chimakhala ndi zovuta.

Gwero la gawoli linali la mutu wakuti "Kuopsa kwa anthu wamba komanso kuwonongeka kwa mtima, komanso kuwonongeka kwamatenda am'mimba komanso ngozi yam'mimba yovuta kwambiri kwa odwala omwe ali ndi vuto la matenda ashuga a 2 malinga ndi mtundu wa kuyamba kwa matenda a hypoglycemic" munkhani ya "Matenda a shuga" 4 4 .9. Olemba - I.V. Misnikova, A.V. Dreval, Yu.A. Kovaleva.

Njira zosiyanasiyana zochizira matenda amtundu wa 2 zimachitika mosiyanasiyana pachiwopsezo cha matenda a mtima, sitiroko komanso kufa kwathunthu mwa odwala. Olemba nkhaniyo adafufuza zambiri zomwe zidalembedwa mu mbiri ya anthu odwala matenda ashuga a dera la Moscow, omwe ndi gawo la boma lolembetsa matenda a shuga a Russia Federation.

Anawunika anthu omwe anapezeka ndi matenda a shuga a 2 mu 2004. Amayerekezera mphamvu ya sulfonylureas ndi metformin ngati amathandizidwa zaka 5.

Zinapezeka kuti mankhwalawa - mankhwala a sulfonylurea - ndizovulaza kuposa zothandiza. Momwe amathandizira poyerekeza ndi metformin:

• chiopsezo cha kufa ndi mtima wonse chidachulukitsidwa,
• chiwopsezo cha mtima - chachulukitsidwa ka 4,6,
• chiopsezo cha matenda a sitiroko chinachulukitsidwa katatu.

Nthawi yomweyo, glibenclamide (Maninil) inali yovulaza kuposa gliclazide (Diabeteson). Zowona, nkhaniyi sichinatchule kuti ndi mitundu iti ya Manilil ndi Diabeteson yomwe imagwiritsidwa ntchito - mapiritsi otulutsidwa kapena ena wamba.

Zingakhale zosangalatsa kuyerekezera zomwe zimachitika ndi odwala omwe ali ndi matenda amtundu wa 2 omwe adalandira mankhwala a insulin m'malo mwa mapiritsi. Komabe, izi sizinachitidwe, chifukwa odwala oterowo sanali okwanira.

Mawonekedwe a Metformin

Ndikufuna kuti tisonyezenso mankhwala ena omwe amagwiritsidwa ntchito ngati mtundu 2 wa shuga - Metformin. Zotsatira za gawo loperekedwalo zimasiyana ndi mankhwala ena chifukwa mwakuti mwatsatanetsatane antihyperglycemic amadziwika. Izi zimadziwika chifukwa ma algorithm omwe amachepetsa shuga m'magazi samayenderana ndi kuchuluka kwa insulin.Makina ochitapo kanthu pankhaniyi akuwoneka motere:

• pali kuponderezana kwamatenda a shuga m'chiwindi,
• kuchuluka kwa chiwopsezo cha gawo la mahomoni kumawonjezeka,
• kukhathamiritsa shuga mayamwidwe algorithm mwachindunji mu minofu ndi chiwindi.

Zitachitika izi, njira ya mayamwidwe a shuga m'matumbo amachepetsa. Zotsatira zabwino za Metformin ziyenera kuthandizidwa kuwongolera kuchuluka kwa glycemia ndikuchepetsa mwayi wamagazi. Poterepa, mwayi wokhala ndi mtima wazomwe zimachitika.

Ndikofunikira kumvetsetsa kuti gawo lomwe limaperekedwa ndi mankhwala limaperekedwa kwa odwala omwe ali ndi kunenepa kwambiri kwa thupi komanso kupezeka kwa kunenepa kwambiri. Zotsatira zoyipa zogwiritsa ntchito piritsi ndi kutsekula m'mimba, komanso mawonetsedwe ena a dyspeptic. Nthawi yomweyo, zovuta zomwe zikuperekedwa zimasowa zokha patatha masiku angapo.

Pofuna kupatula mphamvu ya zoyipa, ndikulimbikitsidwa kuti ndiyambe kuyambiranso ndi piritsi.

Gwiritsani ntchito mankhwalawa mutatha kudya kapena musanagone, mumamwa madzi ambiri kapena tiyi. Mavuto a Metformin amatha kuwunikira patatha pafupifupi sabata kuyambira poyambira kugwiritsa ntchito nthawi zonse. Nthawi zambiri mankhwalawa amadya kamodzi patsiku, zomwe zimakhala bwino komanso zotheka kwambiri kwa odwala matenda ashuga.

Ndi mankhwala ati omwe amaposa?

Chifukwa chake, ndi katswiri yemwe angadziwe chomwe chiri bwino kuposa Maninil kapena Diabeteson. Tisaiwale kuti chilichonse chomwe chatchulidwacho chili ndi zotsutsana komanso zoyipa. Kuphatikiza apo, tisaiwale kuti pamsika wamakono pali zofananira za nyimbo zomwe zaperekedwa.

Mwanjira iyi komanso malingaliro onse a katswiri, zidzatheka kupeza chithandizo chokwanira cha matenda ashuga popanda kuwonjezera zovuta komanso zovuta.

Mbali ya Diabetes

Poletsa shuga la wodwala kuti asadutse momwe amagwiritsidwira ntchito, madokotala amapereka mankhwala a hypoglycemic, omwe ali ambiri ndi Metformin ndi Diabeteson MV. Mlingo ndi nthawi yayitali yotsimikizika yotsimikizika ndi dokotala woyenera, potengera zomwe wodwalayo amapanga ndi shuga wa plasma.

Nthawi zambiri, "Diabetes" amapatsidwa piritsi limodzi kamodzi patsiku. Zilonda zimametsedwa lonse, kutsukidwa ndi madzi okwanira. "Metformin" iyenera kukhala yoledzera kuyambira 2 mpaka 3 pa tsiku kwa 0,5-1 g. Pambuyo pake, mwakufuna kwa dokotala, mlingo ungathe kuwonjezeka mpaka 3 g patsiku. Mapiritsi a Metformin ayenera kumwedwa mutatha kudya ndi 100 ml ya madzi.

Njira ya ntchito

Kuthandizanso kudziwa kuti ndi mankhwala ati omwe akukambirana omwe ali bwino, lingaliro la mfundo zomwe aliyense agwiritse ntchito. Chifukwa chake, "Diabetes" ndi mtundu wachiwiri wa matenda ashuga a shuga omwe amakhala ndi chinthu - gliclazide.

Kusiyana pakati pa Metformin ndi mankhwala ofanana ndikuthekera kwake kutsitsa ndende yamagazi popanda kufunika kowonjezera insulin. Zotsatira zakuchiritsira ndikuti zisinthitse mayamwidwe achilengedwe a chiwindi ndi minofu, komanso kuchepetsa kuyamwa kwa shuga ndi gawo la matumbo.

Ndikofunika kugwiritsa ntchito Diabeteson yodwala matenda a shuga 2 okha. Komabe, matendawa sayenera kuthandizidwa ndimankhwala omwe amafunsidwa ndi anthu omwe ali ndi zotsatirazi ndi zikhalidwe zina:

• Hypersensitivity pazinthu zilizonse zomwe zimapangidwa,
• Mtundu woyamba wa shuga
• aimpso ndi chiwindi ntchito.
• wodwala matenda ashuga
• Kulephera kwa kagayidwe kazakudya chifukwa cha kuchepa kwa insulin,
• nthawi yobala mwana,
• yoyamwitsa
• wazaka 18.

Mankhwala Mankhwala Metformin akuwonetsedwa amtundu woyamba wa shuga wa II komanso mtundu wa II, makamaka ngati matendawa akuphatikizidwa ndi kunenepa kwambiri komanso kuphatikizika kwa shuga m'magazi mwa zakudya komanso zolimbitsa thupi sizingatheke. Simuyenera kugwiritsa ntchito "Metformin" munthawi yomweyo "Diabeteson", ndipo muyenera kukana kutenga chifukwa cha uchidakwa wolephera kapena poyizoni wa mowa.

Kugwirizana

Si zida zonse zamankhwala zomwe zingagwiritsidwe ntchito nthawi imodzi, chifukwa kuphatikiza kwina kwa mankhwalawa ndiopsa kwa thanzi komanso ngakhale moyo wa munthu.

Musanafike podzipaka nokha, ndibwino kukaonana ndi dokotala za momwe mungagwiritsire ntchito mankhwalawa.

Ngati Metformin imagwiritsidwa ntchito limodzi ndi Danazol, antipsychotic, Glucagon, Epinephrine kapena loop diuretics, kuchuluka kwa glucose mu plasma kumatha kuchuluka. Chiwopsezo cha kukhala ndi hyperglycemia chimawonjezeka pamene Diabeteson imagwiritsidwa ntchito limodzi ndi Chlorpromazine, Tetracosactide, ndi Danazol. Mukamamwa mlingo waukulu wa Metformin, kufooketsa mphamvu ya anticoagulants ndikotheka.

Zofananira zina

Mankhwala Metformin amapangidwa ndi kampani yaku Russia Ozone. Metformin hydrochloride imayang'anira zovuta zake za hypoglycemic (kukhazikika kwa shuga wamagazi). Chogulacho chimapangidwa m'mapiritsi okhala ndi 1000, 850 kapena 500 mg pazomwe zimagwira. Omwe amaphatikizidwa ndi mankhwalawa:

• magnesium wakuba,
• Aerosil
• cellcrystalline mapadi,
• polyvidone
• kopovidone
• Opadray II zovuta.

Phukusi lililonse limakhala ndi mapiritsi 60 kapena 30. Mfundo zamankhwala zomwe zimapangitsa kuti mankhwalawo apangidwe zimachokera pakukakamiza kwa kaphatikizidwe ka shuga m'magazi a chiwindi.

Metformin imakulitsa chiwopsezo cha thupi kuti ikhale shuga, chifukwa cha kukhazikika kwazomwe zimachitika ndikusintha. Poterepa, mankhwalawa sakhudza kupanga insulin mthupi. Imakhazikitsanso kapangidwe ka seramu yamagazi ndipo imakhudza kagayidwe ka lipids, chifukwa chomwe kuchuluka kwa lipoproteins, triglycerides ndi cholesterol imasinthika mu thupi.

Njira izi zimathandizira kuwonda. Zochita zapamwamba za metformin hydrochloride zimawonedwa pakadutsa mphindi 120 kuchokera pakamwa. Chakudya chimalepheretsa kuyamwa kwa yogwira pophika m'matumbo.

Ntchito ina ya mankhwalawa ndikumapondereza kuchuluka kwa minyewa. Izi zimakuthandizani kuti muzisunga mawonekedwe a minofu yosalala ya makoma amitsempha yamagazi. Zotsatira zake, wodwalayo amachepetsa kuchepa kwa matenda a mtima.

Metformin sagwiritsidwa ntchito pa nthawi yoyembekezera komanso poyamwitsa ndi hypoglycemia.

Mankhwalawa adapangidwira kukhazikika pazigawo zosiyanasiyana za kunenepa kwambiri komanso matenda a shuga. Kuphatikiza apo, itha kugwiritsidwa ntchito ngati gawo la chithandizo chovuta. Chachikulu contraindication kugwiritsa ntchito mankhwala:

• mimba ndi kuyamwitsa,
• achina,
• kusalolera payekha kwa metformin hydrochloride,
• kuvulala kwambiri kwa chiwindi,
• Zakudya zochepa zopatsa mphamvu
• kuphatikiza ndi mankhwala okhala ndi ayodini
• poizoni
• makomedwe ndi kukomoka chifukwa cha matenda a shuga,
• othandizira opaleshoni ndikuvulala kwambiri,
• lactic acidosis,
• Matenda omwe amapangitsa kuti tisadwale minofu,
• kuphwanya misempha ya adrenal,
• matenda akulu a mtima
• matenda aimpso.

Mosamala, mankhwalawa amaperekedwa kwa odwala ochepa.

Potengera momwe mankhwalawo amagwiritsidwira ntchito, wodwalayo angamve zotsatirazi:

• thupi lawo siligwirizana
• kulawa kwazitsulo pamkamwa,
• kugaya chakudya.

Pofuna kupewa zoyipa, mankhwalawa amayenera kuperekedwa moyang'aniridwa ndi achipatala.

Mankhwalawa amapangidwa ndi kampani yaku France ya Serin. Zomwe zimagwirira ntchito ndi gliclazide. Mankhwalawa amapezeka piritsi. Piritsi limodzi lili ndi 60 mg yogwira pophika.

Chizindikiro chachikulu chakugwiritsira ntchito Diabeteson ndi mtundu wachiwiri wa matenda ashuga.

Zowonjezera zina za mankhwala:

• magnesium wakuba,
• hypromellose (4000 cP ndi 100 cP),
• Aerosil
• maltodextrin.

Mankhwalawa amagulitsidwa m'matumba a mapiritsi a 60 kapena 30. Mfundo ya zake pharmacotherapeutic zochita zachokera kuchepa mu ndende ya shuga mu magazi seramu. Pankhaniyi, thupi limalimbikitsa kaphatikizidwe ka insulin. Zotsatira zake, kuchuluka kwa shuga m'madzi a m'magazi kumakhazikika.

Chizindikiro chachikulu chakugwiritsira ntchito Diabeteson ndi mtundu wachiwiri wa matenda ashuga. Mankhwala amathandizidwa kuti achepetse kulemera kwake ngati palibe chifukwa chochita zolimbitsa thupi komanso kuwona dongosolo lazakudya zopatsa thanzi. Mankhwala amadziwikanso kuti ateteze mawonekedwe a mtima.

• ochepa
• matenda a impso ndi chiwindi.
• precoma, chikomokere ndi ketoacidosis chifukwa cha matenda a shuga,
• Mtundu woyamba wa shuga
• kusalolera kwa munthu yogwira kapena zinthu zothandizira kuchokera pakapangidwe kamankhwala.

Kwa odwala okalamba, mankhwalawa amayikidwa mosamala, ndipo kayendetsedwe kake kamachitika kokha moyang'aniridwa ndi dokotala.

Mawonekedwe a mankhwala oyamba

Choyamba, ndikufuna kukhala pa Diabeteson, yomwe imagwiritsidwa ntchito pa matenda a shuga a 2. Chida ichi ndi chabwino chifukwa chimathandizira kupanga insulini, komanso imathandizira kuchuluka kwa zimakhala.

Kuphatikiza apo, mankhwala omwe aperekedwa amakupatsani mwayi wochepetsera nthawi yakudya chakudya kuti mupange insulin. Palibe mawonekedwe ofunika kwambiri omwe akuyenera kuwonedwa ngati kuchepa kwa cholesterol.

Ndizodziwikanso kuti pamaso pa nephropathy, mankhwalawa amathandizira kuchepetsa kuchuluka kwa proteinuria. M'milandu yambiri, chisankho chomaliza chogwiritsira ntchito ndalamazo chimatengedwa ndi akatswiri pokhapokha kuwunika konse kukamalizidwa.

Mwambiri, odwala matenda ashuga amayesedwa ngati chida chomwe chimathandizira thupi. Komabe, alinso ndi zotsutsana zingapo zomwe zimayenera kuyang'aniridwa kuchokera kwa odwala matenda ashuga.

Ponena za malire, ndikofunikira kulabadira kupezeka kwa mtundu wa 1 shuga mellitus, chikomokere kapena precomatose state.Kuphatikiza apo, kuphwanya lamulo ndikuphwanya impso ndi chiwindi, komanso kuchuluka kwa chidwi cha zigawo zina monga sulfonamides ndi sulfonylurea.

Poona kuti izi sizipangitsa kuti azitha kuthana ndi matendawa, perekani mankhwala omwe amatchedwa Diabeteson.

1. Odwala amatengera kuchepa kwakukulu kwa zizindikiro zamagulu a shuga, pomwe mwayi wa hypoglycemia ndi wochepera 7%,
2. Ndiosavuta kugwiritsa ntchito mankhwala amenewa kamodzi patsiku, ndipo chifukwa chake odwala sakonda kusiya chithandizo chotere cha matendawa,
3. Zizindikiro zakulemera zimachulukanso, koma pang'ono, zomwe nthawi zambiri sizikhudza thanzi lawo.

Akatswiri amalimbikitsa kugwiritsa ntchito Diabeteson, chifukwa ndi yabwino kwambiri kwa odwala ndipo imalekerera popanda mavuto. Ambiri mwa odwala matenda ashuga sawona kukhala kosavuta kugwiritsa ntchito piritsi limodzi pakapita maola 24 aliwonse kuposa kungokhala ndi zochitika zolimbitsa thupi komanso kudya kwambiri.

Mankhwalawa amachepetsa shuga, koma samachepetsa kufa. Ndikofunikira kutengera chidwi kuti akatswiri amapereka mankhwala a shuga, koma izi sizolondola.

Mapangidwe monga Siofor, Glformin ndi Glyukofazh ali m'gulu lomweli.

Ndemanga za Odwala

Sonyezani shuga lanu kapena sankhani jenda kuti mulimbikitsidwe

Zindikirani zaka za mwamunayo

Sonyezani zaka za mkazi

Mankhwala Metformin amapezeka mu mawonekedwe apiritsi osiyanasiyana. Mankhwalawa atha kugulidwa ku malo azamankhwala azigawo mwanjira zotsatirazi:

• 500 mg yogwiritsa ntchito piritsi limodzi,
• 850 mg yogwira pophika
• 1000 mg ya metformin.

Kutengera mlingo wake, malamulo omwera mankhwalawa amadalira. Dziwani kuti ndi madokotala okhawo omwe angalimbikitse kugwiritsa ntchito mankhwalawa, kuphatikizapo m'malo mwa mankhwala omwe adamwa kale.

Njira ya chithandizo imafotokozedwa Mlingo womwe umachokera ku chithunzithunzi chachikulu cha matenda ndi mthupi la wodwalayo. Chizindikiro chachikulu chomwe muyenera kulabadira posankha mlingo ndi kuchuluka kwa glucose m'magazi ndi gawo la kulemera kwa wodwala.

Mlingo wocheperapo womwe mankhwalawa amayamba ndi 500 mg ya mankhwalawa ndikuwonjezereka kwina. Komanso, muyezo umodzi womwewo sungathe kupitirira chiwerengero chomwe chatchulidwa pamwambapa. Kuti mulekerererane bwino mankhwalawo, komanso ngati pali Mlingo wokhazikika, kuchuluka kwake kungagawike pawiri kapena katatu masana.

Nthawi zina, mwachitsanzo, kumwa mankhwalawa chifukwa cha prophylactic, mlingo umayenera kuchepetsedwa kawiri kapena katatu.

Kuchuluka kwa kumwa mankhwalawa kumatheka patatha milungu iwiri ya chithandizo.

Ngati, pazochitika zina, mankhwala adasowa, palibe chifukwa chowalipirira pochulukitsa mlingo wotsatira.

Mukamamwa mankhwalawa, ndikofunikira kuganizira njira yachilengedwe ya kagayidwe kachakudya ndi thanzi labwino.

Ndemanga za odwala zimawonetsa zabwino zomwe chithandizo cha Metformin chimabweretsa. Mtengo wake wapakati m'gawo la Russian Federation ukhoza kuchoka pa ma 170 mpaka 260 rubles.

Ngati ndi kotheka, dokotala yemwe amapezekapo akhoza kusintha mankhwala ena ndi omwewo kapena mawonekedwe omwewo. Mpaka pano, msika wama pharmacological umapereka fanizo zotsatirazi za mankhwala a Metformin, omwe, malinga ndi ndemanga, amakhalanso ndi zotsatirapo zabwino:

1. Glucophage - mapiritsi ochepetsera shuga omwe amapezeka mosiyanasiyana. Chofunikira chachikulu ndi metformin hydrochloride. Zimathandizira kukula kwamwazi wamagazi popanda kuchititsa hypoglycemia. Gawo lamitengo yamapiritsi oterowo, monga lamulo, sapitilira ma ruble 200.
2. Bagomet - mankhwala, momwe muli zinthu ziwiri zogwira ntchito nthawi imodzi - metformin ndi glibenclamide. Ichi ndi mankhwala osakanikirana omwe amaphatikiza mphamvu za Biguanides ndi sulfonylureas. Nthawi zambiri amagwiritsidwa ntchito pochiza matenda amisala a shuga a 2 omwe sanali insulin. Mtengo wapakati wa mankhwalawo ndi ma ruble 210-240.
3. Siofor ndi mankhwala ochokera pagulu la Biguanide, womwe ndi chithunzi chonse cha mapiritsi a Metformin. Mtengo wake wapakati pamasitolo azitawuni amatha kukhala 250 mpaka 350 rubles.
4. Sofamet - mapiritsi ochokera ku gulu la dimethylbiguanides, omwe amapezeka osiyanasiyana. Kutengera kuchuluka kwa zinthu zomwe zimagwira, mtengo wa mankhwalawo umakhazikitsidwa. Monga lamulo, mtengo wa Sofamed m'magawo osiyanasiyana amzindawu sapitilira ma ruble 130,
5. Nova Met.

Mpaka pano, kuchuluka kwa ma analogi kapena kutengera mawu ndi zambiri. Onsewa, monga lamulo, ali ndi zofanana kapena zofanana, koma amasiyana makampani opanga, mtengo, dzina.

Kuphatikiza apo, akatswiri azachipatala amalimbikitsa kugwiritsa ntchito zida zamankhwala zomwe zimakhala, kuphatikiza pa gawo lalikulu lomwe limagwira, ochepera othandizira.

Zambiri pa Metformin zimaperekedwa mu kanema munkhaniyi.

Larisa Petrova, wazaka 36, ​​mzinda wa Omsk

Ndili ndi matenda ashuga a 2. Kuphatikiza apo, ndimakhala ndi mavuto ndi minofu ya mtima komanso kunenepa kwambiri. Ndakhala ndikutenga Metformin kwa nthawi yayitali. Zotsatira zabwino mukamamwa mankhwalawa zimawonedwa mkati mwa maola awiri ndi atatu.

Tamara Volchenkova, wazaka 41, mzinda wa Sergiev Posad

Dotolo adayambitsa matenda a shuga. Mkati mwa maola 6 mpaka 7, mkhalidwe wanga unayenda bwino kwambiri. Mtengo wa mankhwalawa ndiwotsika mtengo, umagulitsidwa ku pharmacy iliyonse. Panalibe zovuta zoyipa pamankhwala.

Vasilisa Shukshina (endocrinologist), wazaka 42, mzinda wa Samara

Mankhwala onse awiriwa amati ndi ntchito yamankhwala. Komabe, zizigwiritsidwa ntchito pokhapokha atakambirana ndi katswiri. Nthawi zambiri, odwala amatchulidwa Metformin, chifukwa imakhala yotsika mtengo pafupifupi 2.

Gennady Pavlyukhin (wochiritsa), wazaka 45, mzinda wa Ufa

Mankhwalawa amapezeka mu mawonekedwe a mapiritsi ndipo amagwiritsidwa ntchito paz matenda ambiri. Nthawi zambiri, ndimapereka Metformin kwa odwala anga, chifukwa ndiotetezeka (angagwiritsidwe ntchito kuyambira azaka 10) ndipo amawononga zochepa.

Diabeteson MV ndi mankhwala ochizira matenda amtundu wa 2. Zomwe zimagwira ndi gliclazide. Zimapangitsa maselo a kancreatic pancreatic beta kuti apange insulin yambiri, yomwe imatsitsa shuga. Zimatanthauzira zochokera ku sulfonylurea.

Ma MV ndi mapiritsi osinthidwa amasinthidwe. Gliclazide samamasulidwa kwa iwo, koma wogawana kwa maola 24. Izi zimapereka phindu mankhwalawa matenda a shuga. Komabe, matenda ashuga sawoneka ngati chisankho choyambirira cha matenda amtundu wa 2.

Ndikulimbikitsidwa kukhazikitsidwa pokhapokha ngati metformin. Werengani mu nkhani zatsatanetsatane za momwe mungagwiritsire ntchito, contraindication, mlingo, maubwino ndi zovuta za Diabeteson MV. Dziwani zomwe mankhwalawa amatha kusintha kuti pasakhale zovulaza kuchokera ku zotsatirapo zake zoyipa.

Type 2 shuga, ngati kudya komanso kuchita masewera olimbitsa thupi sizithandiza kwenikweni. Kupewa mavuto a shuga mellitus: kuchepetsa chiopsezo cha microvascular (nephropathy, retinopathy) ndi macrovascular complication (myocardial infarction, stroke) mwa kuwunika kwambiri magazi.

• mtundu 1 shuga
• matenda ashuga ketoacidosis, precoma, chikomokere,
• kugwiritsa ntchito miconazole,
• anthu ochepa komanso owonda, mapiritsi awa ndi oyipa, werengani nkhani ya LADA-shuga mwatsatanetsatane,
• kwambiri aimpso ndi hepatic kusowa (mu izi, muyenera jekeseni insulin, osamwa mapiritsi a shuga),
• kugwiritsa ntchito miconazole,
• Mimba ndi kuyamwa
• wazaka 18
• Hypersensitivity to gliclazide, zotumphukira zina za sulfonylurea, olemba piritsi.

Fotokozerani mosamala:

• matenda akulu a mtima dongosolo (mtima kulephera, kugunda kwa mtima, ndi zina),
• hypothyroidism - chithokomiro chatsika,
• adrenal kusakwanira kapena pituitary gland,
• Matenda a chiwindi kapena impso, kuphatikizapo matenda a shuga,
• zakudya zopanda thanzi kapena zosasamala, uchidakwa,
• okalamba.

Mankhwala a Diabeteson mu mapiritsi amodzi ndi kumasulidwa kosinthika (MV) amaperekedwa kwa odwala omwe ali ndi matenda a shuga a 2, omwe kudya ndi kuchita masewera olimbitsa thupi samayendetsa bwino matenda. The yogwira pophika mankhwala ndi gliclazide.

Ndikulimbikitsidwa kuti odwala omwe ali ndi matenda a shuga a 2 sayenera kufotokozedwa poyambira, koma mankhwala a Metformin - Siofor, Glucofage kapena Glformin. Mlingo wa metformin pang'onopang'ono umachulukitsidwa mpaka pafupifupi mg mg patsiku.

Gliclazide mapiritsi otulutsidwa otulutsidwa mosiyanasiyana kwa maola 24. Mpaka pano, machitidwe othandizira odwala matenda ashuga amalimbikitsa kuti madokotala azigwiritsa ntchito Diabeteson MV kwa odwala awo omwe ali ndi matenda a shuga a 2, m'malo mwa m'badwo wam'mbuyomu sulfonylureas. Mwaona

mwachitsanzo, nkhani "Zotsatira za kafukufuku wa DYNASTY (" Diabeteson MV: pulogalamu yowonera pakati pa odwala omwe ali ndi matenda a shuga 2 omwe amachitika pafupipafupi ")" munyuzipepala ya Problems of Endocrinology No. 5/2012, wolemba M. V. Shestakova, O. K Vikulova ndi ena.

Mankhwala oyamba a Diabeteson MV amapangidwa ndi kampani yopanga mankhwala Laboratory Serviceier (France). Kuyambira mu Okutobala 2005, adasiya kupereka mankhwala am'badwo wapitalo ku Russia - mapiritsi a shuga a shuga a 80 mg.

Tsopano mutha kugula kokha mapiritsi a Diabeteson MV - mapiritsi otulutsidwa amasinthidwe. Fomu ya Mlingo iyi ili ndi zabwino zake, ndipo wopanga adaganiza zokhazokha.

Kukonzekera komwe kaphatikizidwe kake ndi gliclazide mu mapiritsi otulutsira msanga tsopano kwatha. Ndikofunika kugwiritsa ntchito Diabeteson MV kapena mawonekedwe ake m'malo mwake.

Anthu akayamba kumwa diabetes, shuga wawo wamagazi amatsika mofulumira. Odwala amadziwa izi pakuwunika kwawo. Mapiritsi osinthidwa osinthidwa nthawi zambiri samayambitsa hypoglycemia ndipo nthawi zambiri amalekeredwa bwino.

Palibe kubwereza komwe kumanenedwa za mankhwala a Diabeteson MV pomwe munthu wodwala matenda ashuga amadandaula za hypoglycemia. Zotsatira zoyipa zokhudzana ndi kufinya kwam'mimba sizimakhazikika nthawi yomweyo, koma patatha zaka 2-8. Chifukwa chake, odwala omwe adayamba kumwa mankhwalawa posachedwa samatchula.

Kwa zaka 4 ndakhala ndikumwa piritsi la Diabeteson MV 1/2 m'mawa nthawi yam'mawa. Chifukwa cha izi, shuga imakhala yabwinobwino - kuyambira 5.6 mpaka 6.5 mmol / L. M'mbuyomu, idafika 10 mmol / l, mpaka idayamba kuthandizidwa ndi mankhwalawa. Ndimayesetsa kuchepetsa maswiti komanso kudya pang'ono, monga adokotala adalangizira, koma nthawi zina ndimatsika.

Zowonjezera

Ndikufuna kuti tisonyezenso mankhwala ena omwe amagwiritsidwa ntchito ngati mtundu 2 wa shuga - Metformin. Zotsatira za gawo loperekedwalo zimasiyana ndi mankhwala ena chifukwa mwakuti mwatsatanetsatane antihyperglycemic amadziwika.

• pali kuponderezana kwamatenda a shuga m'chiwindi,
• kuchuluka kwa chiwopsezo cha gawo la mahomoni kumawonjezeka,
• kukhathamiritsa shuga mayamwidwe algorithm mwachindunji mu minofu ndi chiwindi.

Zitachitika izi, njira ya mayamwidwe a shuga m'matumbo amachepetsa. Zotsatira zabwino za Metformin ziyenera kuthandizidwa kuwongolera kuchuluka kwa glycemia ndikuchepetsa mwayi wamagazi. Poterepa, mwayi wokhala ndi mtima wazomwe zimachitika.

Ndikofunikira kumvetsetsa kuti gawo lomwe limaperekedwa ndi mankhwala limaperekedwa kwa odwala omwe ali ndi kunenepa kwambiri kwa thupi komanso kupezeka kwa kunenepa kwambiri. Zotsatira zoyipa zogwiritsa ntchito piritsi ndi kutsekula m'mimba, komanso mawonetsedwe ena a dyspeptic.

Gwiritsani ntchito mankhwalawa mutatha kudya kapena musanagone, mumamwa madzi ambiri kapena tiyi. Mavuto a Metformin amatha kuwunikira patatha pafupifupi sabata kuyambira poyambira kugwiritsa ntchito nthawi zonse.

Chifukwa chake, ndi katswiri yemwe angadziwe chomwe chiri bwino kuposa Maninil kapena Diabeteson. Tisaiwale kuti chilichonse chomwe chatchulidwacho chili ndi zotsutsana komanso zoyipa. Kuphatikiza apo, tisaiwale kuti pamsika wamakono pali zofananira za nyimbo zomwe zaperekedwa.