Kodi ndibwino kuti muchepetse kunenepa - Siofor kapena Glukofazh?
Siofor amadziwika kuti ndi wotchuka kwambiri padziko lonse lapansi ngati mankhwala a matenda a shuga. Mankhwalawa amakhala ndi metformin, yomwe imathandizira maselo kubwezeretsa chidwi cha insulin, potero kupewa insulin. Kuphatikiza apo, Siofor amathandizira kuchepetsa cholesterol yamagazi ndikuchepetsa chiopsezo chokhala ndi matenda amtima. Koma mwayi wake wosakayikira ndikuchepetsa thupi pang'onopang'ono komanso moyenera.
Kugwiritsa
Chidziwitso chachikulu pakugwiritsa ntchito Siofor ndi mtundu wa matenda a shuga a 2, kupewa kwake ndi chithandizo. Nthawi zambiri, ziyenera kumwedwa ngati chakudya ndi masewera olimbitsa thupi sizinadzetse zotsatira zabwino.
Mapiritsi a Siofor ayenera kumwedwa ngati mankhwala okhawo komanso monga mankhwala. Nthawi zambiri ndimankhwala omwe amachepetsa kuchuluka kwa shuga m'magazi (mapiritsi ochepetsa shuga, jakisoni wa insulin).
Imwani mankhwala ndikudya kapena mutatha kudya. Mutha kuwonjezera mlingo, koma ziyenera kuchitika pang'onopang'ono ndipo mutatha kufunsa katswiri.
Contraindication
Pali matenda ndi mikhalidwe ina yomwe kugwiritsa ntchito Siofor koletsedwa.
- Type 1 shuga mellitus (kusiyanasiyana ndiko kukhalapo kwa kunenepa kwambiri, komwe kumathandizidwa ndi mankhwalawa).
- Kuperewera kwa insulin komwe kumapangidwa ndi kapamba (kungachitike ndi mtundu wachiwiri).
- Coma ndi ketoacidotic chikomokere.
- Micro ndi macroalbuminemia ndi uria (zomwe zili mu mapuloteni a albumin ndi globulin mu mkodzo ndi magazi).
- Matenda a chiwindi ndi ntchito yake yosakwanira.
- Ntchito zosakwanira za mtima ndi mitsempha yamagazi.
- Kulephera kopindulitsa.
- Kuchepetsa hemoglobin m'magazi.
- Zochita ndi opaleshoni ndikuvulala.
- Mowa wambiri.
- Mimba ndi mkaka wa m`mawere.
- Ana osakwana zaka 18.
- Aliyense tsankho kwa zinthu za mankhwala.
- Kutenga njira zakulera zamkamwa, monga momwe chiopsezo cha kutenga pakati kosakonzekera chikukula.
- Okalamba pambuyo pa 60 omwe amatanganidwa ndi kulimbikira.
Siofor pakuchepetsa thupi
Mankhwala Siofor samawonetsedwa ngati mankhwala omwe cholinga chake chachikulu ndikuchepa. Komabe, ndemanga zambiri komanso mayesero azachipatala amatsimikizira kuti mankhwalawa ndi abwino kwambiri kuti achepetse thupi. Mapiritsi amachepetsa chilakolako chofuna kudya ndikuthandizira kufulumizitsa kagayidwe. Izi zimathandizira kuchotsa ma kilogalamu angapo a kulemera kwakukulu.
Komabe, zotsatira zake zimangokhala munthawi ya kumwa mankhwalawa. Pambuyo kupatula, kulemera kumabwezeretsedwa mwachangu makamaka chifukwa cha mafuta m'thupi.
Komabe, pali zabwino za Siofor pamankhwala ena. Ili ndi zovuta zingapo zoyipa. Kungoyimbira m'mimba, kutsekula m'mimba ndi kumatulutsa pang'ono ndizotheka. Mtengo ulinso wotsika kuposa ma analogu ena, omwe amachititsa kuti mankhwalawa akhale okwera mtengo kwa ambiri.
Kutenga mapiritsi a Siofor osatsata zakudya zama carb ochepa kumatanthauza kusayenda pansi. Kuchotsa mapaundi owonjezera kumatheka pokhapokha mukamadya zakudya komanso kupezeka kwa zolimbitsa thupi. Kumwa mankhwala ochulukirapo kungayambitse mkhalidwe wa lactic acidotic, womwe umapha. Chifukwa chake, m'chiyembekezo chochepetsa thupi mwachangu, ndibwino kuthamanga kuposa kuwonjezera mlingo womwe umalimbikitsa.
Siofor wa matenda ashuga amtundu wa 2
Malamulo oyambira kupewa matenda a shuga a 2 amaphatikizanso kukhala ndi moyo wathanzi. Popeza dziko lili ndi kuchuluka kwa anthu, kupewa kungaphatikizepo kusintha kwa chakudya komanso kuchuluka kwa zochita zolimbitsa thupi. Komabe, owerengeka okha amatsatira lamuloli. Kwa ambiri, ndikofunikira kutenga Siofor ngati njira yowonjezera kuwonda. Komabe, mankhwalawa sangakuthandizeni kukwaniritsa zotsatira zabwino popanda kudya komanso kuchita masewera olimbitsa thupi.
Glucofage imatha kutengedwa ngati chiwonetsero cha Siofor cha matenda ashuga a 2. Ku mulingo wina, ndizabwino, koma palinso zovuta zina.
Ubwino wake ndiwakuti Glucofage yayitali imakhala ndi mphamvu yayitali, ndiye kuti metformin imamasulidwa ku mankhwalawa pasanathe maola 10. Pomwe Siofor mu theka la ola likutha kuchitapo kanthu. Komabe, palinso glucophage osatenga nthawi yayitali.
Kodi Glucophage ndi wabwino bwanji kuposa Siofor?
- Kwa Siofor, pali mlingo ndipo ndi bwino kumamwa kangapo patsiku. Mapiritsi a Glucophage amatengedwa kamodzi patsiku.
- Zotsatira zoyipa kuchokera m'matumbo am'mimba ndizochepa, makamaka chifukwa chovomerezeka.
- Palibe kusintha kwadzidzidzi m'kukoka kwa glucose m'magazi, makamaka m'mawa ndi maola ausiku.
- Ngakhale mulingo wotsika, siwotsika ndi Siofor pakuchepetsa shuga.
Monga mapiritsi a Siofor, Glucofage imalembedwa mtundu wachiwiri wa matenda ashuga ndipo kuwonda kumathandiza.
Kodi kuchepetsa kunenepa kumatanthauza chiyani?
- Zosokoneza za lipid zosokoneza m'thupi zimabwezeretseka.
- Zakudya zomanga thupi sizimaphwanyidwa konse m'thupi, zomwe zimatanthawuza kuti sizimayamwa ndikuwasintha kukhala mafuta.
- Imasinthasintha kuchuluka kwa shuga m'magazi ndikuchepetsa kuchuluka kwa cholesterol.
- Kuchepetsa chilala chifukwa cha kuchepa kwa kutulutsa kwa insulin.
Mapiritsi a Siofor
Mwa mankhwala omwe amapezeka mu njira yothandizira anthu odwala matenda a shuga a 2, omwe amawagwiritsa ntchito kwambiri ndi Siofor. Amagwiritsidwa ntchito pochiza matenda omwe alipo komanso kupewa, chifukwa amasintha kukana insulin, chifukwa chachikulu chodumphira mu shuga ndipo, makamaka, kunenepa kwambiri. Izi zakhala chifukwa chachikulu chomwe adokotala angapangire Siofor kuti achepetse thupi kwa wodwala wake. Imapezeka mu mawonekedwe a mapiritsi okhala ndi magawo osiyanasiyana a chinthucho.
Kuphatikiza apo, kugwiritsa ntchito mankhwalawa kumakhudza:
- mtima
- Zizindikiro za triglycerides,
- cholesterol.
Mankhwala a Siofor ochepetsa thupi amalembetsa "mabonasi" ena ambiri, osawerengera mphamvu yakuwongolera shuga:
- Kuchepetsa chilala, komwe kumathandizira kuti muzidya kapena kusinthasintha zakudya.
- Kuwonekera kwa mahomoni a chithokomiro (azimayi zimawavuta kuchepetsa thupi chifukwa cha zovuta za dongosolo la endocrine).
Siofor - zikuchokera
Kuti mumvetsetse bwino lomwe phindu la mankhwalawa poyerekeza ndi kuchepa thupi, kuphunzira malangizowo kuyenera kuyamba ndi mndandanda wazinthu zomwe zimapezeka. Kuphatikizidwa kwa Siofor kumatsegula gawo lotere monga metformin - uwu ndi woimira gulu la Biguanide, lomwe limapangitsa chidwi cha thupi m'thupi. Ine.e. Kugwiritsa ntchito mankhwalawa kumathandizira kuchepetsa shuga, ndipo mwayi wofunikira wa metformin ndi kusapezeka kwa impso. Zotsatira zoyipa za gawo ili la Siofor ndizosowa kwambiri, ndipo mwa "mabonasi" omwe amagwiritsidwa ntchito, kuchepa kwa TSH akuwonetsa.
Kuphatikiza pa metformin, Siofor ili ndi zinthu zothandiza (kuphatikizapo zipolopolo):
- hypromellose
- povidone
- magnesium wakuba,
- macrogol
- titanium dioxide.
Siofor - malangizo ogwiritsira ntchito
Kodi mudaganizira zochepetsa thupi kudzera kuchepa kwa kusinthasintha kwa insulin, kapena mukufuna kupewa matenda ashuga, muyenera kudziwa amene akulimbikitsidwa kugwiritsa ntchito Siofor, momwe angachitire komanso momwe angasankhire mlingo. Malangizo a Siofor akuti ndi shuga wokha (mtundu II) wokha womwe ungayesedwe ngati chinthu chokhacho chogwiritsidwa ntchito, pomwe mapiritsiwa amatengedwa ngati "gawo lomalizira", amagwiritsidwa ntchito pokhapokha potsatira zakudya ndipo amathandizidwa kuchita zolimbitsa thupi.
Siofor 500 pakuchepetsa thupi
Mlingo wocheperako wa metformin womwe ungatheke kwa Siofor (malinga ndi assortment yama Russian pharmacies) ndi 500 mg. Kugwiritsa ntchito piritsi loterolo kumaloledwa ngakhale mwa ana, ndipo anthu omwe akuwona njira yochepetsera kulemera ndi Siofor, ndikofunika kuchita izi. Pa anthu odwala matenda ashuga, madokotala amati njira ziwiri zomwe mungagwiritse ntchito mankhwalawa:
- monga monotherapy - 500 mg kawiri pa tsiku,
- kuphatikiza ndi insulin (ngati kudalira) - kuchuluka kuchokera ku 500 mg mpaka 2000 mg patsiku, i.e. kuchokera pa 1 mpaka 4 phwando.
Ngati titha kunena momwe titha kutenga Siofor 500 kuti muchepetse kunenepa, ndiye kuti ndikofunika kukhazikika pa lingaliro la monotherapy lomwe latsimikiziridwa ndi malangizo a boma: kumwa mapiritsi 1 a Siofor 500 mapiritsi mwezi umodzi. patsiku. Chitani izi ndi chakudya kapena mukatha kudya, chifukwa kugwiritsa ntchito metformin kwadzala ndi mkwiyo wam'mimba. Mlingo wocheperako wa Siofor pakuchepetsa thupi umakhudza pang'ono, koma zovuta zomwe zimachitika kwa izo ndizosowa. Ndi kulolerana kwabwino, malangizowo amalola kuwonjezera kuchuluka kwa mapiritsi awiri a Siofor.
Siofor 850
Njira iyi ya mankhwalawa, molingana ndi malangizo a boma, ndiyabwino kwambiri kwa odwala matenda ashuga, koma mwa munthu wathanzi amadziwika kuti ndi "lolemetsa", choncho imayenera kuyamba ndi theka la piritsi. Siofor 850 pakuchepetsa thupi imagwiritsidwa ntchito pang'ono poyerekeza ndi Siofor 500, koma malangizo ndi zomwe malangizo ochokera kwa wopanga akufanana:
- Chiwerengero cha tsiku ndi tsiku cha 3,000 mg cha metformin, ngakhale kuwonda msanga, sikuletsedwa kupitirira.
- Njira yochepetsera thupi mankhwalawa ndi mwezi kapena zochepa.
- Pambuyo pa masabata awiri, mutha kuyamba kumwa mankhwalawa - 2 mapiritsi a 850 mg patsiku.
Siofor 1000
Mtundu wamphamvu kwambiri wa mankhwalawa okhathamira omwe amaperekedwa ndi makampani opanga mankhwala ndi Siofor 1000. Madokotala amalingalira za kugwiritsa ntchito mankhwalawa pachimake cha mankhwalawa kuti achepetse thupi osafunikira, popeza izi zimakhala zowononga thupi. Impso zimatha kuvutika kwambiri, chifukwa metformin siyotetezedwa kwathunthu, ndipo kuchuluka kwa shuga ndikuwonekeratu. Musanayankhe nokha kuti mungatenge Siofor 1000 kuti muchepetse thupi, pitani mayeso a shuga, chifukwa Mlingo, malinga ndi malangizo, amasankhidwa molingana ndi malangizowo.
Malingaliro ochepa a mankhwalawa:
- Mlingo woyambirira wa kuchepa thupi ndi piritsi 1/4. M'masiku ochepa mutha kumwa theka la piritsi, ndipo kumapeto kwa sabata, ngati palibe zotsatira zoyipa, ndimakupsopsona.
- Panthawi yogwiritsa ntchito mankhwalawa, ndikofunikira kuti muchepetse mafuta osavuta m'zakudya, monga Amawaletsa kutengeka kwawo. Kuchokera pamawunikidwe mutha kuwona kuti kugwiritsa ntchito piritsi ili ndi ma cookie kapena maswiti kumabweretsa kuyipa kwambiri m'mimba.
Siofor pa nthawi yoyembekezera
Amayi oyembekezera kuchepa thupi pa mankhwalawa ndikosayenera. Madokotala aku Russia amaletseratu Siofor pa nthawi yomwe ali ndi pakati, akufotokozera malingaliro awo ponena kuti kuchuluka kwa maphunziro pa thanzi la ana omwe adabereka azimayi omwe amamwa mankhwalawa sikokwanira kuti voti yotsimikizika kapena yotsutsa. Ngati mukukayika zokhudzana ndi chitetezo cha mankhwalawo, mayi woyembekezerayo ali bwino ndikuwonetsetsa kuti asiyire piritsi lodabwitsali, chifukwa pali njira zambiri zochepetsera thupi (zofatsa) panthawi yodikirira mwana.
Siofor - analogues
Madokotala amangoti mankhwala 2 okha ndi omwe amathandizanso kupezeka pa matenda a shuga komanso kusinthasintha kwa shuga malinga ndi gawo la chinthu chomwe chikugwiridwacho ndi zomwe mwaphunzitsidwa:
Analogue iliyonse ya Siofor ndiyofanana ndi mankhwalawa m'chigawo chake chachikulu. Amatha kupezekanso muyezo womwewo - kuchokera 500 mpaka 1000 mg, kotero mfundo yogwiritsira ntchito sasintha, malangizowo akubwereza pafupifupi kalata yomwe kalata yopita kwa Siofor. Kusiyanako kokha ndikomwe kapangidwe kazilombedwe ndikuti madokotala amalangiza Glucofage kuti amwe asanadye, osati pambuyo pake. Ponena za momwe mungatengere Metformin kuti muchepetse kunenepa, apa chilichonse chikufanana ndi malangizo a mankhwala a Glyukofazh.
Siofor - contraindication ndi mavuto
Chitetezo cha mankhwalawa ndi chofunikira kwambiri - kuchokera pazowunikira mutha kuwona kuti thupi limatha kuyankha mwamphamvu kwa metformin m'masiku oyamba kukonzekera. Zotsatira zoyipa za Siofor ndi ziti? Kwambiri ndikusanza ndi kutsekula m'mimba, i.e. kugaya chakudya, koma kumatha kusokonezeka chikumbumtima, komanso chifukwa cha bongo wambiri - chikomokere. Ngati pakukula kwa mankhwalawa ndi mankhwalawa simunatenge mafuta osavuta m'zakudya zanu, zimakupatsirani gal.
Maupangiri ochepa pamayendedwe a boma:
- Mukamamwa mankhwalawa, zakudya za tsiku ndi tsiku ziyenera "kulemera" zopatsa mphamvu zopitilira 1000.
- Zochita zolimbitsa thupi zazitali, makamaka aerobic, ndizoletsedwa.
- Ndi zoletsedwa kumwa mowa ndi mankhwala okhala ndi ayodini.
Zotsatira zamankhwala awa, madokotala amatcha matenda a shuga a I (amatha kugwiritsidwa ntchito pokhapokha ngati mukumvera, motsutsana ndi insulin), matenda a impso, chiwindi. Oncology ndi chifukwa choletsa kuchepa kwa thupi ndi Siofor. Malinga ndi malangizo a boma, simuyenera kumwa mankhwalawa panthawi ya matenda opatsirana komanso mukamamwa mowa. Kuphatikiza ndi mankhwala okhala ndi ethanol ndikofunikira kupewa.
Mtengo Siofor
Mtengo wapakati wa mankhwalawa ku Moscow umachokera ku ruble 300 mpaka 350, wotsimikiziridwa ndi Mlingo wa metformin. Mu tebulo, mtengo wa Siofor wa mapiritsi 60 akuwonetsedwa popanda kutumizidwa (ngati sitolo kapena mankhwala ogulitsa mankhwala amapereka) pazakuyerekezera. Chithunzichi ndi ichi:
Dzinalo
Mtengo
Siofor500
Siofor850
Siofor1000
Kanema: Matenda a shuga ndi Kuchepetsa Siofor
Sindinawone kusiyana kwakukulu pakati pa Siafor1000 ndi Siafor500, ndinamwa zonse ziwiri. Piritsi limodzi lililonse, maphunzirowa anali milungu iwiri. Ngakhale mulingo wocheperako, ngakhale mlingo wake umakhala wokwera, zimangoyambitsa chimodzi - kuphunzitsanso koipa! Mukayesa kudya ma cookie, kusanza kumayamba, chifukwa mankhwalawa amaletsa chakudya. Zimakhudzanso munthu wanga momwemo, koma ndachimwira thupi langa.
Siafor500 ndi olowa m'malo mwa 24/7! Ndikofunika kuyesa kudya china chosiyana ndi masamba / zipatso (chimadumpha phala, koma pazifukwa zina popanda mkaka), zotsatirapo zonse "zokondweretsa" zimatseguka nthawi yomweyo - m'mimba zimayamwa, kusekera msana, kupweteka m'mimba. Pakati pa sabata la "maulendo" amenewa, ndinasiya chizolowezi chochepetsa thupi komanso chakudya komanso kupewa kunenepa, komanso ndinataya makilogalamu 4 pamwezi.
Sindimadwala matenda ashuga, ndidapunthwa pa Siofor mwangozi, ndagula (zabwino, zotsika mtengo), ndimamwa mwezi umodzi. Sindinawone zotsatira zowonjezera pakuchepetsa thupi, ndipo ndimanena kuti zinatsalira ndi 2,5 makilogalamu pazakudya zomwe zimafunidwa ndi malangizo a mankhwalawo. Koma mndandanda wazotsatira zoyipa ndizambiri, ngakhale mavitamini sangaphatikizidwe ndi mankhwala.
Ndinkamwa Siofor850 kwa masabata atatu enieni, ndikupezerapo mwayi pazomwe mzanga amamuchepetsa. Matumbo adayamba kukhumudwa, ngakhale piritsi lidatengedwa pambuyo pa chakudya chamtima. Ndaphunzira kuti ndibwino kumwa mankhwala pambuyo poyesa kuchuluka kwa shuga, osamangoyamwa mwachangu potsatira malangizo. Ndidapambana mayeso, ndidayamba kumwa theka la piritsi - zidapita bwino.
Siofor ndi Glyukofazh - nkhani mwatsatanetsatane - http://diabet-med.com/siofor/. Mu kanema wamasiku ano, tikambirana za mankhwala a Siofor ndi Glucofage. Amatengedwa kuti athandizidwe komanso kupewa matenda amtundu wa 2, komanso kuwonda. Siofor ndi mtundu wodziwika bwino wa matenda ashuga 2 padziko lapansi. Ndiwo mankhwala okhawo omwe amavomerezedwa popewa matenda ashuga. Glucophage ndi chimodzimodzi ndi Siofor. Palinso mapiritsi okhala ndiutali wotchedwa Glucofage Long. Amakhala okwera mtengo kwambiri, koma ali ndi mwayi kuposa Siofor yokhazikika. Chizindikiro chakugwiritsa ntchito Siofor - mtundu 2 matenda a shuga, osati chithandizo chokha, komanso kupewa. Kuphatikiza pa kuchiza matenda a shuga, Siofor amathandizanso kuti achepetse thupi ndi ma kilogalamu angapo. Awa ndi mapiritsi otchuka azakudya. Amatengedwa ndi azimayi zikwizikwi, chifukwa amalimbikitsa kuchepa thupi komanso nthawi yomweyo amakhala otetezeka, osakhala ndi zovuta zoyipa.Siofor sayenera kutengedwa ngati muli ndi matenda amtundu wa 1 shuga, impso zazikulu, chiwindi, kapena vuto la mtima. Mukamamwa mapiritsi awa, simuyenera kumwa mowa. Osatenga Siofor kapena Glucofage pa nthawi yapakati. Siofor sayambitsa zovuta zoyipa, koma kugaya chakudya m'mimba kumachitika nthawi zambiri. Odwala amadandaula kuti amatulutsa, kupweteka kwam'mimba, mpweya, kutsegula m'mimba, kunyansidwa komanso kutsekemera kwazitsulo mkamwa. Pakapita kanthawi, thupi limasinthasintha. Zitatha izi, Zizindikiro zake zimachepa kapena kuzimiririka. Mungapewe bwanji mavuto? Kuti muchite izi, tengani Siofor ndi chakudya, pamodzi ndi chakudya. Ndipo onjezani mlingo wake pang'onopang'ono. Mlingo waukulu wa Siofor ndi magalamu 2-3 patsiku, nthawi zambiri amakhala magalamu a 2,5. Koma muyenera kuyamba kumwa ndi 500 kapena 850 mg patsiku, kenako ndikuwonjezera pang'onopang'ono. Ndikofunikanso kuyesa Glucophage Long. Amayambitsa zovuta m'mimba kawiri kwambiri kuposa Siofor wamba. Glucophage Long amadziwikanso kuti amachepetsa shuga m'magazi a 2 shuga. Mapiritsi a Siofor kapena Glucofage okha amathandizira kuchepetsa shuga m'magazi ndikutaya mapaundi owonjezera ochepa. Koma ngati mungagwiritse ntchito limodzi ndi zakudya zamagulu ochepa, ndiye kuti zotsatira zake zingakusangalatseni. Mutha kuonda mosavuta musanva njala, pambuyo pake kulemera kwakanthawi kumakhalapo kwa nthawi yayitali. Kwa odwala matenda a shuga a 2, tsatirani dongosolo lonse la chithandizo lomwe limanenedwa pa HTDIdiabetes-med.com/. Tikukuphunzitsani kuti musunge shuga wabwinobwino popanda kufa ndi njala, kuchita masewera olimbitsa thupi komanso jakisoni wa insulin.
Kodi mankhwala amathandizira bwanji?
Analogue wamba ya siofor ndi mankhwala osokoneza bongo. M'malo mwake, awa ndi mankhwala ofanana, chifukwa muzochitika zonse ziwiri metmorphine ngati chinthu chogwira ntchito. Chifukwa cha izi kuti chiwindi cha munthu chimachepetsa kupanga shuga, yemwe amayamba kudyedwa ndi minofu yambiri.
Zotsatira zazikulu zomwe Siofor 1000 (glucophage) imalola kukwaniritsa, zomwe ndibwino kutenga monga momwe madokotala amafotokozera, zimafotokozedwa motere:
- kuchepa kwamtima
- kagayidwe kamabwerera mwakale,
- magazi cholesterol yafupika,
- Kulakalaka zakudya zotsekemera kumachepa.
Milandu Yosankhidwa
Ndikofunikira kumwa mankhwalawa ndi zakudya, malangizo amatiuza. Ndikofunika kufunsa dokotala za njira yabwino. Komabe, musaiwale kwa kaminiti kuti mankhwala monga glucophage (Siofor 1000 kapena mitundu ina) amathandizira kwambiri metabolism yofunika.
Madokotala amalembera izi muzochitika pamene chithandizo chamankhwala ochiritsira chokhudzana ndi zochitika zolimbitsa thupi sichimapereka zotsatira. Ngati wodwalayo achulukitsa thupi pang'ono, kum'patsa mankhwala a metmorphine kungakhale kosavulaza.
Mwa contraindication kugwiritsa ntchito mankhwala a Siofor 850 a kuwonda.
- matenda a impso kapena chiwindi
- matenda opatsirana
- Mimba ndi kuyamwa
- matenda a mtima
- kusalolera payekhapayekha,
- osalimbikitsa kuti azitenga glucophage kwa ana ndi okalamba, komanso omwe amagwira ntchito yolumikizidwa ndi ntchito yayikulu.
Samalani mukamatenga
Tsopano tiyeni tikambirane zomwe zimapangitsa kuti kuchepa kwa thupi kuwonongeke. Pali mitundu yosiyanasiyana ya mankhwala - 500, 850 ndi 1000, omwe amalumikizidwa ndi kuphatikizika kwa chinthu chomwe chikugwirika. Odwala ambiri adachita kuchepa kwa makilogalamu anayi mpaka 12 omwe adalandira kale chithandizo cha mwezi umodzi.
Malangizo ogwiritsa ntchito akutiuza momwe tingakwaniritsire kuchepa kwamphamvu thupi. Khalani okonzeka kuti mankhwalawa amatha kupweteketsa mavuto ena, monga mseru komanso kudzimbidwa, colic m'matumbo, kutopa konse, ndi kutentha thupi.
Monga mukudziwa, malangizo ogwiritsira ntchito amapezeka kwa okhawo ochenjera okha. Ambiri aife timangoyang'ana m'maso mwake, tikuyembekeza zotsatira zabwino.
Nthawi zambiri, pagawo loyamba, Siofor 500 imalembedwa kuti muchepetse thupi, monga wodalirika kwambiri kwa thupi pakati pa mzere womwe ulipo.
Ambiri mwa osewera komanso omanga thupi adakumana ndi zowopsa zamankhwala omwe amatchedwa glucophage. Kuyerekeza kuchepa kwa malo ogulitsira amafuta ochepa, adadziwonongera kwambiri impso zawo.
Izi ndichifukwa choti metmorphine, yomwe ndi gawo la mankhwala a glucophage, samabweretsa zotsatira zoyenera ngati atagwiritsidwa ntchito pazithandizo zochizira. Kuti mankhwalawa athe kuwonongera mafuta m'thupi lanu, muyenera kumwa mankhwalawa. Izi zimatha kuwononga impso, makamaka kuphatikiza kuchita masewera olimbitsa thupi kwambiri. Nthawi zina, ngakhale zotsatira zakupha zinalembedwera mwa iwo omwe malangizo omwe angagwiritsire ntchito mankhwalawo sanathe kuwatsimikizira kuti anali owona.
Udindo wa chinthu chogwira ndi zomwe wapeza
M'mayiko asayansi, metmorphine, yomwe ndi gawo la Siofor 500 pakuchepetsa thupi, adafotokozedwanso zaka 20 zapitazo. Mankhwala moyenerera adamuwonetsa chidwi, ndipo nthawi zosiyanasiyana ankanenedwa za mphamvu yake yolephera komanso ya analgesic. Dzina loti glucophage, kapena glucophage, lidayamba kugwiritsidwa ntchito patatha zaka makumi atatu, atadziwika kuti mankhwalawo amatha kuyamwa glucose omwe anali m'thupi.
Mayeso ambiri azachipatala amayamikira bwino lomwe chipambano chake pochiza matenda ashuga. Kuyambira nthawi imeneyi, Siofor 1000 yakhala mankhwala oletsa kudwala matenda ashuga ndipo yapulumutsa miyoyo yambiri ya anthu panthawiyi.
Mpaka pano, Siofor 1000 yalembedwa ngati mankhwala ofunika kwambiri ndi World Health Organisation. Zimakuthandizani kuti muchepetse kuyamwa kwa shuga m'magazi a anthu. Chifukwa chake, popanda kuchuluka kwa glucose, maselo samadzaza ndi mphamvu yofunikira. Zotsatira zake, wodwalayo amadya chakudya chamagulu ambiri ndipo akupeza msanga thupi.
Pano, sofor yochepetsa thupi, yokhala ndi metmorphine ya magawo 1000 kapena ochepera wamba, atha kutithandiza. Zimawonjezera kukhudzika kwa ma receptors ndipo zimatha kuthetsa kwathunthu zotsatira za insulin pazambiri zamafuta ochulukirapo.
Kodi kuchepa thupi kumachitika bwanji?
Za chiwindi, apa glucophage kapena siofor 1000 imachepetsa mapangidwe a glycogen ndi glucose. Magazi a shuga amchere amachepa chifukwa cha kutseguka kwa kuthandizira kwa michere ya michere, chifukwa chomwe wodwalayo amasiya kumva njala.
Kuchuluka kwa chimbudzi cha michere kumacheperanso. Ngakhale kuti ma saofor amtundu wa 1000 kapena zochepa amathandizira kuchuluka kwa mafuta acids, iwo amalowa m'matumbo, komwe amamwetsa. Pazifukwa izi, mankhwalawa adayamba kusangalatsidwa ndi omanga thupi.
Malangizo pakugwiritsa ntchito kwake akuwonetsa kuti ngati mumadya pafupipafupi, mutha kuchepetsa chidwi chanu, ndipo izi zidzapangitsa kuchepa kwa chakudya. Kuchuluka kwa shuga m'magazi kumachepera kwambiri, kenako kulemera kwa thupi kumachepa. Mwa njira, pakati pa mapiritsi ambiri a mapiritsi ochepetsa thupi Siofor 1000, komabe, adadziwika kuti ndi amodzi otetezeka. Ponena za odwala matenda ashuga, ngati matendawa adapezeka munthawi yake, jakisoni wa insulin atha kupewedwa.
Zolinga zakufuna kwa mankhwala
Mwa mankhwala onse okhala ndi metmorphine, ndiye glucophage ndi siofor 1000 omwe amadziwika kuti ndi otchuka kwambiri m'maiko olankhula Russia. Cholinga cha izi chimatchedwa kuthekera kwawo kuphatikiza ndikuchita bwino.
Palinso glucophage yomwe imagwira ntchito kwakanthawi kogulitsa. Zowona, zimatenga ndalama zambiri kuposa mnzake. Anthu ambiri amagwiritsa ntchito Siofor 1000 kuphatikiza mankhwala ena omwe amachepetsa insulin kapena shuga.
Kwa onse omwe ali ndi chidwi ndi funso loti "Siofor pakuchepetsa thupi", timayang'anira chidwi chakuti zotsatira za kuchepa thupi zimasungidwa panthawi yolamulira. Ngati simukuyang'ananso malingaliro anu pazakudya, zakudya ndi masewera, ndiye kuti mafuta osungira amabwerera mwachangu kwambiri. Chifukwa chake, musanayambe kukalandira kwambiri, pezani kufunsa kwa endocrinologist kapena dokotala wanu. Ngati ndi kotheka, perekani mayeso ofunikira kuti mupeze zotsutsana.
Kodi mungapeze bwanji zotsatira zabwino?
Tengani glucophage kapena Siofor 1000 ndikofunikira pamodzi ndi zakudya. Ndibwino ngati chakudya chanu chanthawi imeneyi ndichopatsa mphamvu. Choyamba, khazikitsani zakudya zomwe mumadya. Mulimonsemo, musapitirire mlingo woyenera pofunafuna mwachangu komanso momveka bwino.
Pazochepera, pamakhala chiwopsezo cha zovuta pamagwiritsidwe ntchito ka mgaya. Amayi musaiwale kuti Siofor 1000 (glucophage) imawonjezera mwayi wokhala ndi pakati osakonzekera.
Ngati zikuwoneka kuti mutayamba kumwa mankhwalawo, kulemera kwanu kumachepetsedwa mosathamanga, ndemanga zotsatirazi zakuthandizira zimakhala zothandiza kwa inu:
- yambani kudya zakudya zamafuta ochepa,
- masewera olimbitsa thupi, makamaka yambani kusuntha kwambiri,
- Poyerekeza ndi mapiritsi ena azakudya, Siofor 1000 ili ndi mphamvu zambiri.
- osapitilira muyeso womwe wakupatsani, kapena womwe umalimbikitsidwa ndi momwe mungagwiritsire ntchito.
Malangizo a mankhwala a Siofor (metformin)
Nkhaniyi ili ndi "zosakanikirana" zama malangizo a Siofor, zambiri kuchokera m'magazini azachipatala ndi kuwunika kwa odwala omwe amamwa mankhwalawo. Ngati mukufuna malangizo a Siofor, mupeza zonse zofunikira ndi ife. Tikukhulupirira kuti tinatha kutumiza zidziwitso za mapiritsi otchuka kwambiri mwanjira yomwe ili yabwino kwambiri kwa inu.
Siofor, Glucofage ndi fanizo lawo
Dzina la malonda |
---|
Siofor |
Glucophage |
Bagomet |
Glyformin |
Metfogamma |
Metformin Richter |
Metospanin |
Novoformin |
Forethine |
Forin Pliva |
Sofamet |
Langerine |
Metformin teva |
Nova Met |
Metformin Canon |
Glucophage kutalika |
Methadiene |
Diaformin OD |
Metformin MV-Teva |
Glucophage ndi mankhwala oyamba. Ikutulutsidwa ndi kampani yomwe idapanga metformin ngati mankhwala ochizira matenda a shuga a mtundu 2. Siofor ndi analogue ya kampani yaku Germany ya Menarini-Berlin Chemie. Awa ndi mapiritsi otchuka kwambiri a metformin m'maiko olankhula Chirasha ndi ku Europe. Ndiwotsika mtengo ndipo amagwira ntchito bwino. Glucophage kutalika - mankhwala osagwira. Amayambitsa zovuta m'mimba kawiri poyerekeza ndi metformin yokhazikika. Glucophage kutalika amakhulupiriranso kuti amachepetsa shuga bwino mu shuga. Koma mankhwalawa ndi okwera mtengo kwambiri. Zina zonse za mapiritsi a metformin omwe alembedwa pamwambapa sizimagwiritsidwa ntchito. Palibe deta yokwanira pakukwanira kwake.
Zizindikiro zogwiritsidwa ntchito
Type 2 matenda a shuga a mellitus (osadalira insulin), ochizira komanso kupewa. Makamaka kuphatikiza kunenepa kwambiri, ngati mankhwala othandizira pakudya ndi maphunziro akuthupi opanda mapiritsi sikugwira ntchito.
Pochiza matenda a shuga, Siofor angagwiritsidwe ntchito ngati monotherapy (mankhwala okhawo), komanso kuphatikiza ndi mapiritsi ena ochepetsa shuga kapena insulin.
Siofor yoletsa matenda ashuga amtundu wa 2
Njira zabwino zopewera matenda ashuga a 2 ndikuyamba kukhala ndi moyo wathanzi. Makamaka, kuwonjezera zolimbitsa thupi ndi kusintha kwa kavalidwe. Tsoka ilo, ambiri mwa odwala m'moyo watsiku ndi tsiku samatsata malangizowo pakusintha moyo wawo.
Chifukwa chake, funso lidafunsa mwachangu njira yopewera matenda a shuga a mtundu wachiwiri pogwiritsa ntchito mankhwala. Kuyambira mu 2007, malingaliro aboma ochokera ku American Diabetes Association okhudza kugwiritsa ntchito Siofor popewa matenda a shuga adawonekera.
Kafukufuku yemwe adakhala zaka zitatu akuwonetsa kuti kugwiritsa ntchito Siofor kapena Glucofage kumachepetsa chiopsezo chokhala ndi matenda ashuga ndi 31%. Yerekezerani: ngati mungasinthe ndikukhala ndi moyo wathanzi, ndiye kuti chiwopsezochi chidzachepera ndi 58%.
Kugwiritsa ntchito mapiritsi a metformin popewa kumangolimbikitsidwa mwa odwala omwe ali ndi chiopsezo chachikulu cha matenda a shuga. Gululi limaphatikizapo anthu azaka zosaposa 60 onenepa kwambiri omwe mwanjira imodzi kapena zingapo zotsatirazi:
- Glycated hemoglobin wambiri - pamwamba 6%:
- ochepa matenda oopsa
- mafuta otsika kwambiri a "cholesterol" wabwino kwambiri m'magazi,
- okwera magazi triglycerides,
- panali mtundu wachiwiri wa matenda ashuga achibale.
- index index yayikulu kuposa kapena yofanana ndi 35.
Odwala otere, kusankha kwa Siofor popewa matenda osokoneza bongo a 250-850 mg 2 kawiri pa tsiku angakambirane. Masiku ano, Siofor kapena Glucophage yake yosiyanasiyana ndi mankhwala okhawo omwe amatengedwa ngati njira yolepheretsa matenda ashuga.
Malangizo apadera
Muyenera kuwunika ntchito ya chiwindi ndi impso musanapereke mapiritsi a metformin kenako miyezi 6 iliyonse. Muyenera kuonanso kuchuluka kwa lactate m'magazi 2 pachaka kapena kangapo.
Mankhwala a shuga, kuphatikiza kwa sofor ndi zotumphukira za sulfonylurea ndi chiopsezo cha hypoglycemia. Chifukwa chake, kuwunika mosamala kuchuluka kwa shuga m'magazi kumafunika kangapo patsiku.
Chifukwa cha chiwopsezo cha hypoglycemia, odwala omwe amatenga siofor kapena glucophage ali osavomerezeka kuti achite nawo zochitika zofunikira kuti azigwiritsa ntchito kwambiri komanso nthawi yayitali.
Zotsatira zoyipa
10-25% ya odwala omwe akutenga Siofor ali ndi madandaulo okhudzana ndi zovuta zam'mimba, makamaka kumayambiriro kwa chithandizo. Uku ndikumva kukoma kwa "chitsulo" mkamwa, kusowa kudya, kutsekula m'mimba, kutulutsa magazi ndi mpweya, kupweteka m'mimba, kusanza komanso kusanza.
Kuchepetsa pafupipafupi komanso kuchuluka kwa zotsatirazi, muyenera kudya siofor mukamadya kapena mukatha kudya, ndikuwonjezera pang'onopang'ono mankhwala. Zotsatira zoyipa kuchokera m'matumbo am'mimba sizomwe zimapangitsa kuti mankhwalawa asule. Chifukwa pakapita kanthawi nthawi zambiri amachoka, ngakhale ndi mlingo womwewo.
Matenda a metaboliki: osowa kwambiri (omwe ali ndi mankhwala osokoneza bongo, pamaso pa matenda ophatikizika, momwe kugwiritsidwa ntchito kwa Siofor kumatsutsana, ndi uchidakwa), lactic acidosis imatha kukhazikika. Izi zimafunikira kusiya kwa mankhwala msanga.
Kuchokera pa hematopoietic dongosolo: zina - megaloblastic anemia. Ndi chithandizo cha nthawi yayitali ndi siofor, kukula kwa B12 hypovitaminosis ndikotheka (kuyamwa). Nthawi zambiri pamakhala zovuta zina zoyipa - zotupa pakhungu.
Kuchokera ku endocrine dongosolo: hypoglycemia (ndi mankhwala osokoneza bongo).
Pharmacokinetics
Pambuyo pakukonzekera kwa pakamwa, kuchuluka kwambiri kwa metformin (ichi ndi mphamvu ya siofor) m'magazi am'magazi imatha kufikira pafupifupi maola 2,5. Ngati mumamwa mapiritsi ndi chakudya, ndiye kuti mayamwidwe pang'ono amachepetsa ndikuchepetsa. Kuchuluka kwa metformin mu plasma, ngakhale pamlingo waukulu, sikapitilira 4 μg / ml.
Malangizowo akuti kukhudzika kwake kwathunthu mwa odwala athanzi ndi pafupifupi 50-60%. Mankhwala sakukhudzana ndi mapuloteni a plasma. Pulogalamuyi imachotsedwa mkodzo kwathunthu (100%) osasinthika. Ichi ndichifukwa chake mankhwalawa sanalembedwe kwa odwala omwe aimpso glomerular kusefa kosachepera 60 ml / min.
Kuwonekera kwa aimpso kwa metformin kopitilira 400 ml / min. Amapitilira kuchuluka kwa kusefedwa kwa glomerular. Izi zikutanthauza kuti siofor imachotsedwa m'thupi osati kokha ndi kusefera, komanso kudzera mwa chobisalira mu proximal renal tubules.
Pambuyo pakukonzekera pakamwa, theka la moyo lili pafupifupi maola 6.5.Polephera kwa aimpso, kuchuluka kwa maselo a siofor kumachepa molingana ndi kuchepa kwa chilolezo cha creatinine. Chifukwa chake, theka la moyo limatenga nthawi yayitali ndipo kuchuluka kwa metformin m'madzi a m'magazi kumakwera.
Kodi Siofor amachotsa calcium ndi magnesium m'thupi?
Kodi kutenga Siofor kumakulitsa kuchepa kwa magnesium, calcium, zinc ndi mkuwa m'thupi? Akatswiri aku Romania adaganiza zofunsa. Kuphunzira kwawo kunakhudza anthu 30 azaka 30-60 omwe adangopezeka ndi matenda a shuga a 2 ndipo omwe sanalandiridwe nawo kale. Onsewa adalembedwa Siofor 500 mg 2 kawiri pa tsiku. Siofor yekhayo amene adayikidwa kuchokera pamapiritsi kuti awone momwe zimakhalira. Madotolo adonetsetsa kuti zomwe aliyense akudya zimakhala ndi 200 mg ya magnesium patsiku. Magnesium-B6 mapiritsi sanalembedwe kwa aliyense.
Gulu lolamulira la anthu athanzi, lopanda matenda a shuga, linapangidwanso. Anayesanso zomwezo kuti afananize zotsatira zawo ndi za anthu odwala matenda ashuga.
Odwala a matenda a shuga a mtundu wachiwiri omwe anali ndi vuto la impso, matenda a chiwindi, matenda a m'mimba, pakati, matenda otsekula m'mimba, kapena omwe amamwa mankhwala okodzetsa sanali kuloledwa kuchita nawo phunziroli.
Mlingo wa magnesium m'magazi a odwala omwe ali ndi matenda amtundu wa 2 ndi ochepa, poyerekeza ndi anthu athanzi. Kuperewera kwa magnesium m'thupi ndi chimodzi mwazomwe zimayambitsa matenda ashuga. Matenda a shuga atakula kale, impso zimachotsa shuga wambiri mkodzo, ndipo chifukwa cha izi, kutayika kwa magnesium kumakulirakulira. Mwa odwala matenda ashuga omwe apanga zovuta, pali kuchepa kwambiri kwa magnesium kuposa omwe ali ndi matenda ashuga popanda zovuta. Magnesium ndi gawo la michere yoposa 300 yomwe imayendetsa metabolism yama protein, mafuta ndi chakudya. Zatsimikiziridwa kuti kuchepa kwa magnesium kumathandizira kukana kwa insulin kwa odwala omwe ali ndi metabolic syndrome kapena matenda a shuga. Ndipo kutenga mankhwala othandizira a magnesium, ngakhale pang'ono, komabe kumakulitsa chidwi cha maselo kuti apange insulin. Ngakhale njira yofunikira kwambiri yothanirana ndi insulin ndi chakudya chamafuta ochepa, ena onse kumbuyo kwake amakhala mbali yayikulu.
Zinc ndi imodzi mwazinthu zofunika kwambiri zofufuza m'thupi la munthu. Zimafunikira njira zopitilira 300 mu maselo - ntchito ya enzyme, kaphatikizidwe ka mapuloteni, kuwonetsera. Zinc ndiyofunikira kuti chitetezo cha mthupi chizigwira ntchito, kukhalabe ndi moyo wathanzi, kuletsa kusintha zinthu mwaulere, kuchepetsa kuchepa komanso kupewa khansa.
Mkuwa nawonso ndi chinthu chofunikira kutsatira, gawo la michere yambiri. Komabe, ma ayoni amkuwa amaphatikizidwa ndikupanga mitundu yoyipa ya oxygen yomwe imagwira ntchito (ma radicals aulere), motero, ndiwothandiza. Onse akusowa komanso mkuwa owonjezera mthupi umayambitsa matenda osiyanasiyana. Komanso, zochulukirapo ndizofala. Matenda a 2 a shuga ndi matenda osachiritsika omwe amapanga mitundu yambiri yaulere, yomwe imapangitsa kupsinjika kwa oxidative kuwononga maselo ndi mitsempha yamagazi. Kafukufuku akuwonetsa kuti thupi la odwala matenda ashuga nthawi zambiri limadzaza ndi mkuwa.
Pali mapiritsi osiyanasiyana amtundu wa shuga. Mankhwala odziwika kwambiri ndi metformin, omwe amagulitsidwa pansi pa mayina a Siofor ndi Glucofage. Zimatsimikiziridwa kuti sizikuyambitsa kulemera, koma zimathandizira kuchepetsa thupi, zimapangitsa kuti magazi a cholesterol, komanso zonsezi popanda zotsatira zoyipa. Siofor kapena glucophage yowonjezera amalimbikitsidwa kuti alembe yomweyo, wodwala akangopezeka ndi matenda a shuga a 2 kapena metabolic syndrome.
Madokotala aku Romania adaganiza zoyankha mafunso otsatirawa:
- Kodi mulingo wachilengedwe wanji wa minyewa komanso zinthu zomwe zimapezeka mthupi la odwala omwe apezeka ndi matenda a shuga a 2? Wokwezeka, wotsika kapena wabwinobwino?
- Kodi kutenga metformin kumakhudza bwanji magnesium, calcium, zinc ndi mkuwa m'thupi?
Kuti achite izi, adayetsa odwala odwala matenda ashuga:
- kuchuluka kwa magnesium, calcium, zinc ndi mkuwa m'madzi am'magazi,
- zomwe zili ndi magnesium, calcium, zinc ndi mkuwa pakukodza kwa mkodzo kwa maola 24,
- mulingo wa erythrocyte magnesium (!),
- komanso cholesterol chabwino "chabwino" komanso "choyipa", triglycerides, shuga othamanga wamagazi, glycated hemoglobin HbA1C.
Odwala a shuga a Type 2 adayezetsa magazi ndi mkodzo:
- kumayambiriro kwa phunziroli.
- ndiye kachiwiri - mutatha miyezi 3 mutamwa metformin.
Kumayambiriro kwa phunziroli
Kumayambiriro kwa phunziroli
Tikuwona kuti mwa odwala matenda ashuga zomwe zili ndi magnesium ndi zinc m'magazi zimachepetsedwa, ndikuyerekeza ndi anthu athanzi. Pali zolemba zambiri m'magazini a Chingerezi azachipatala omwe amatsimikizira kuti kusowa kwa magnesium ndi zinc ndi chimodzi mwazomwe zimayambitsa matenda ashuga a 2. Mkuwa wophatikiza ndi womwewo. Pazidziwitso zanu, ngati mumatenga zinc m'mapiritsi kapena makapisozi, imakhutitsa thupi ndi zinc ndipo nthawi yomweyo imachotsa mkuwa wowonjezera kuchokera pamenepo. Ndi anthu ochepa omwe amadziwa kuti zowonjezera zazitini zimakhala ndi zochita zowirizi. Koma simuyenera kunyamulidwa kwambiri kuti pasakhale kuperewera kwamkuwa. Tengani zinc mu maphunziro 2-4 kawiri pachaka.
Zotsatira zakuwonetsa kuti kutenga metformin sikukweza kuchepa kwa kufufuza zinthu ndi mchere m'thupi. Chifukwa chofufumitsa cha magnesium, zinc, mkuwa ndi calcium mumkodzo mwa odwala omwe ali ndi matenda a shuga a 2 sizinawonjezeke pambuyo pa miyezi itatu. Potengera momwe mankhwalawo amathandizira ndi mapiritsi a Siofor, odwala matenda ashuga adakweza michere mthupi. Olemba kafukufukuyu akuti izi zikuchitika ndi Siofor. Ndikukhulupirira kuti mapiritsi a shuga alibe chochita ndi izi, koma kuti omwe amaphunzira nawo adadya zakudya zopatsa thanzi pomwe madotolo amawayang'anira.
Panali mkuwa wambiri m'magazi a anthu odwala matenda ashuga kuposa anthu athanzi, koma kusiyana ndi gulu lolamuliraku sikunali kopanda tanthauzo. Komabe, madotolo aku Romania adawona kuti mkuwa wambiri m'magazi, umakhala wolimba kwambiri. Kumbukirani kuti phunziroli lidakhudza odwala 30 omwe ali ndi matenda ashuga a 2. Pambuyo pa chithandizo cha miyezi itatu, adaganiza zosiya 22 mwa Siofor, ndipo mapiritsi ena 8 adawonjezeredwa - sulfonylurea. Chifukwa Siofor sanatsitse shuga wawo mokwanira. Omwe anapitiliza kuthandizidwa ndi Siofor anali ndi 103.85 ± 12.43 mg / dl yamkuwa m'magazi am'magazi, ndipo omwe amafunikira kupereka zochokera ku sulfonylurea anali ndi 127.22 ± 22.64 mg / dl.
- Kutenga Siofor pa 1000 mg patsiku sikukuonjezera kuchuluka kwa calcium, magnesium, zinki ndi mkuwa kuchokera mthupi.
- Kuchuluka kwa magnesium m'magazi, kumawerengera bwino shuga.
- Kuchuluka kwa magnesium m'maselo am'magazi, kumapangitsa shuga ndi glycated hemoglobin bwino.
- Mkuwa wambiri, umayipanso kwambiri shuga, glycated hemoglobin, cholesterol ndi triglycerides.
- Mukakhala ndi hemoglobin wokwera kwambiri, ndiye kuti nthaka yambiri imathira mkodzo.
- Kuchuluka kwa calcium m'magazi sikusiyana mwa odwala omwe ali ndi matenda ashuga a 2 komanso anthu athanzi.
Ndikuwonetsa chidwi chanu chakuti kuyezetsa magazi kwa plasma magnesium sikodalirika, sikuwonetsa kuchepa kwa mcherewu. Onetsetsani kuti mukuwunika zomwe zili m'magazi ofiira a m'magazi. Ngati izi sizingatheke, ndipo mukumva zofooka za magnesium m'thupi, ndiye ingotengani mapiritsi a magnesium okhala ndi vitamini B6. Ndiotetezeka pokhapokha mutakhala ndi matenda a impso. Nthawi yomweyo, calcium sikhala ndi vuto lililonse la matenda ashuga. Kutenga mapiritsi a magnesium okhala ndi mavitamini a B6 ndi zinc ndizofunikira kwambiri kuposa calcium.
Zotsatira za pharmacological
Siofor - mapiritsi ochepetsa shuga wamagazi kuchokera pagulu la Biguanide. Mankhwala amapereka kuchepa kwa kuchuluka kwa shuga m'magazi onse pamimba yopanda kanthu ndikatha kudya. Sichimayambitsa hypoglycemia, chifukwa sichimalimbikitsa kuteteza kwa insulin. Machitidwe a metformin mwina amatengera njira zotsatirazi:
- kuponderezedwa kwa kuchuluka kwa shuga mu chiwindi mwa kupondereza gluconeogeneis ndi glycogenolysis, ndiko kuti, siofor imalepheretsa kaphatikizidwe ka shuga kuchokera ku amino acid ndi zina "zopangira", komanso kupewa kutulutsa kwake m'misika yama glycogen,
- kusintha kwa glucose kutengera zotumphukira minofu ndikugwiritsa ntchito kumeneko pochepetsa insulin kukana maselo, ndiye kuti, minyewa yathupi limazindikira kwambiri zomwe zimapangitsa insulini, motero maselo "amayamwa" glucose mwa iwo eni,
- Kuchepetsa mayamwidwe a shuga m'matumbo.
Mosasamala kanthu za kukhudzidwa kwa glucose m'magazi, siofor ndi mankhwala ake othandizira metformin amasintha kagayidwe ka lipid, kutsika kwa triglycerides m'mwazi, kumawonjezera zomwe zili ndi cholesterol "yabwino" (kachulukidwe kakang'ono) ndikuchepetsa kuchuluka kwa cholesterol "yoyipa" yotsika m'magazi.
Molecule ya metformin imaphatikizidwa mosavuta mu lipid bilayer ya nembanemba maselo. Siofor imakhudza ma cell a cell, kuphatikiza:
- kuponderezedwa kwa kupukutira kwa mitochondrial,
- kuchuluka kwa ntchito ya tyrosine kinase ya insulin receptor,
- kukondoweza kwa kusintha kwa glucose transporter GLUT-4 kupita ku membrane wa plasma,
- kutsegula kwa AMP-activated protein kinase.
Kuchita kwachilengedwe kwa nembanemba ya khungu kumadalira kuthekera kwa magawo a mapuloteni kuyenda mozungulira mu lipid bilayer. Kuwonjezeka kwa kusakhazikika kwa membrane ndizodziwika bwino m'matenda a shuga, omwe angayambitse zovuta za matendawa.
Kafukufuku wasonyeza kuti metformin imachulukitsa kuchuluka kwa madzi am'magazi a anthu. Chofunika kwambiri ndi mphamvu ya mankhwalawa pa mitochondrial membrane.
Siofor ndi Glucofage zimakulitsa chidwi cha insulin makamaka maselo a minofu yolimba, komanso pang'ono - adipose minofu. Malangizo a boma amati mankhwalawa amachepetsa mayamwidwe a shuga m'matumbo ndi 12%. Odwala mamiliyoni ambiri awona kuti mankhwalawa amachepetsa chilimbikitso. Potengera maziko akumamwa mapiritsiwo, magazi sakhala wandiweyani, mwayi wopanga mapangidwe owopsa amachepetsa.
Glucophage kapena Siofor: kusankha?
Glucophage kutalika ndi mtundu watsopano wa metformin. Amasiyana ndi siofor chifukwa imakhala ndi nthawi yayitali. Mankhwala kuchokera piritsi samamwa nthawi yomweyo, koma pang'onopang'ono. Mwa Siofor wamba, 90% ya metformin imatulutsidwa piritsi mkati mwa mphindi 30, ndipo mu glucophage yayitali - pang'onopang'ono, maola opitilira 10.
Ngati wodwala satenga siofor, koma glucophage nthawi yayitali, ndiye kuti kufalikira kwa metformin m'magazi a magazi kumayamba pang'onopang'ono.
Ubwino wa glucophage wautali kuposa momwe zimakhalira
- ndikokwanira kumwa kamodzi patsiku,
- Zotsatira zoyipa za m'mimba thirakiti yomweyo
- Ndi bwino kuwongolera shuga m'magazi komanso m'mawa pamimba yopanda kanthu
- Kuchepetsa misempha ya m'magazi kulibe vuto poyerekezera ndi kupuma "wamba".
Zomwe muyenera kusankha - siofor kapena glucophage yayitali? Yankho: ngati simulekerera siofor chifukwa cha kutulutsa, kufinya kapena kutsegula m'mimba, yesani glucophage. Ngati zonse zili bwino ndi Siofor, pitilizani kumwa, chifukwa mapiritsi amtundu wa glucophage ndi okwera mtengo kwambiri. Madokotala othandizira odwala matenda a shuga Dr. Bernstein amakhulupirira kuti glucophage ndiwothandiza kwambiri kuposa mapiritsi ofulumira a metformin. Koma mazana a odwala ambiri anali otsimikiza kuti siofor wamba amachita mwamphamvu. Chifukwa chake, kulipira zowonjezera kwa glucophage kumveka, kupatula kuchepetsa kukhumudwa.
Mlingo wa mapiritsi a Siofor
Mlingo wa mankhwalawa umakhazikitsidwa nthawi iliyonse payokha, kutengera kuchuluka kwa shuga m'magazi ndi momwe wodwalayo amalolera kulandira chithandizo. Odwala ambiri amasiya chithandizo cha Siofor chifukwa cha kusefukira, kutsegula m'mimba, komanso kupweteka kwam'mimba. Nthawi zambiri zotsatira zoyipa izi zimachitika chifukwa cha kusankha kwa mlingo woyenera.
Njira yabwino yotsatirira Siofor ndi kuchuluka pang'onopang'ono kwa mlingo. Muyenera kuyamba ndi mlingo wotsika - osaposa 0,5-1 g patsiku. Awa ndi mapiritsi 1-2 a mankhwala a 500 mg kapena piritsi limodzi la Siofor 850. Ngati palibe zotsatirapo zoyipa kuchokera m'matumbo am'mimba, ndiye kuti pambuyo pa masiku 4-7 mutha kuwonjezera mlingo kuchokera pa 500 mpaka 1000 mg kapena kuchokera ku 850 mg mpaka 1700 mg patsiku, i.e. kuchokera pa piritsi limodzi patsiku mpaka awiri.
Ngati pansipa pali zovuta kuchokera pamimba, ndiye kuti muyenera "kubwezeranso" mankhwalawo kwa omwe anali m'mbuyomu, kenako ndikuyesetsa kuti muwonjezere. Kuchokera pamalangizo a Siofor, mutha kudziwa kuti mlingo wake wothandiza ndi 2 pa tsiku, 1000 mg iliyonse. Koma nthawi zambiri zimakhala zokwanira kutenga 850 mg 2 kawiri pa tsiku. Kwa odwala akulu m'thupi, mulingo woyenera kwambiri ungakhale 2500 mg / tsiku.
Mlingo wapamwamba tsiku lililonse wa Siofor 500 ndi 3 g (mapiritsi 6), Siofor 850 ndi 2.55 g (mapiritsi atatu). Avereji ya tsiku ndi tsiku ya Siofor® 1000 ndi 2 g (mapiritsi 2). Mlingo wake waukulu tsiku lililonse ndi 3 g (mapiritsi atatu).
Mapiritsi a Metformin mulingo uliwonse amayenera kumwa ndi chakudya, osafuna kutafuna, wokhala ndi madzi ambiri. Ngati mlingo wa tsiku ndi tsiku woposa piritsi limodzi, gawani pawiri. Ngati mwaphonya mapiritsi, simuyenera kulipirira izi pomwa mapiritsi ambiri nthawi ina.
Kutenga nthawi yayitali motani ya Siofor - izi zimatsimikiziridwa ndi adokotala.
Bongo
Ndi bongo wa Siofor, lactate acidosis imatha kukhazikika. Zizindikiro zake: kufooka kwambiri, kupuma, kugona, kugona mseru, kusanza, kutsegula m'mimba, kupweteka kwam'mimba, kuzizira kwamphamvu, kutsika kwa magazi, Reflex bradyarrhythmia.
Pakhoza kukhala zodandaula za kupweteka kwa minofu, kusokonezeka ndi kuwonongeka, kupumira mofulumira. Chithandizo cha lactic acidosis ndichizindikiro. Izi ndizovuta zomwe zingayambitse imfa. Koma ngati simupitirira muyeso ndipo ndi impso zonse zili bwino ndi inu, ndiye kuti kuthekera kwake ndi zero.
Kuyanjana kwa mankhwala osokoneza bongo
Mankhwalawa ali ndi katundu wosiyana ndi ena onse. Uwu ndi mwayi wophatikiza ndi njira ina iliyonse yochepetsera kuchuluka kwa shuga m'magazi. Siofor ikhoza kutumikiridwa molumikizana ndi mtundu wina uliwonse wa mapiritsi a 2 a shuga kapena insulin.
Siofor itha kugwiritsidwa ntchito limodzi ndi mankhwala awa:
- makasitomala (zotumphukira zochokera ku sulfonylurea, meglitinides),
- thiazolinediones (glitazones),
- mankhwala a incretin (analogues / agonists a GLP-1, DPP-4 zoletsa),
- mankhwala omwe amachepetsa mayamwidwe wamafuta (acarbose),
- insulin ndi mawonekedwe ake.
Pali magulu a mankhwala omwe amatha kupititsa patsogolo zotsatira za metformin pakuchepetsa magazi, ngati agwiritsidwa ntchito nthawi imodzi. Izi ndi zotumphukira za sulfonylurea, acarbose, insulin, NSAIDs, Mao inhibitors, oxytetracycline, ACE inhibitors, clofibrate zotumphukira, cyclophosphamide, beta-blockers.
Malangizo a Siofor akuti magulu ena a mankhwala amatha kufooketsa mphamvu yake yochepetsa shuga ya magazi ngati mugwiritsa ntchito mankhwalawa nthawi yomweyo. Awa ndi GCS, njira zakulera za pakamwa, epinephrine, sympathomimetics, glucagon, mahomoni a chithokomiro, zotumphukira za phenothiazine, zotumphukira za nicotinic acid.
Siofor imatha kufooketsa zotsatira za anticoagulants. Cimetidine amachepetsa kuchotsedwa kwa metformin, yomwe imawonjezera chiopsezo cha lactic acidosis.
Osamamwa mowa pamene mukutenga Siofor! Kugwiritsa ntchito pamodzi ndi ethanol (mowa), chiopsezo chotenga zovuta zowopsa - lactic acidosis imachuluka.
Furosemide imachulukitsa kuchuluka kwa metformin m'madzi a m'magazi. Pankhaniyi, metformin imachepetsa kuchuluka kwakukulu kwa furosemide mu madzi am'magazi ndi theka la moyo wawo.
Nifedipine amalimbikitsa mayamwidwe ndi pazipita kuchuluka kwa metformin m'madzi am'magazi, amachedwa mayeso.
Mankhwala a Cationic (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, vancomycin), omwe amatulutsidwa m'matumba, kupikisana ndi machitidwe ogwiritsira ntchito ma tubular. Chifukwa chake, ngati atatenga nthawi yayitali, amatha kuonjezera kuchuluka kwa metformin m'madzi a m'magazi.
M'nkhaniyi, takambirana mwatsatanetsatane mitu yotsatirayi:
- Siofor pakuchepetsa thupi,
- Mapiritsi a Metformin popewa komanso kuchiza matenda a shuga 2,
- Ndiwofunika kuti muthe kumwa mankhwalawa mtundu 1 wa shuga.
- Momwe mungasankhire mlingo kuti musakhumudwitsidwe.
Kwa odwala matenda a shuga a 2, musadziikire malire pakumwa Siofor ndi mapiritsi ena, koma tsatirani pulogalamu yathu ya matenda ashuga a 2. Kufa msanga chifukwa cha vuto la mtima kapena sitiroko ndiye vuto. Ndipo kukhala munthu wodwala pakama chifukwa cha zovuta za matenda ashuga kumakhala kowopsa. Phunzirani kwa ife momwe mungathetsere matenda ashuga popanda zakudya "zanjala", maphunziro olimbitsa thupi komanso mu 90-95% ya milandu popanda jakisoni wa insulin.
Ngati muli ndi mafunso okhudzana ndi mankhwalawa Siofor (Glucofage), ndiye kuti atha kufunsidwa mu ndemanga, oyang'anira tsamba amayankha mwachangu.
Chifukwa chiyani mankhwalawa amawerengedwa?
Siofor anapangidwira kuti achepetse kuchuluka kwa shuga m'magazi musanadye kapena mukatha kudya. Mankhwalawa samalimbikitsa kuchepa kwamphamvu kwa shuga, chifukwa kubisala kwa kapamba pogwiritsa ntchito mankhwalawa sikuyambitsa. Mankhwalawa Siofor amaperekedwa kwa odwala matenda a shuga mellitus 2 kwa akulu ndi ana atatha zaka 10. Wothandiziratu matenda othandizira amathandizidwanso kwa anthu onenepa kwambiri ngati zolimbitsa thupi ndi zakudya zosagwira. Siofor ali ndi mtundu wina wa kumasulidwa kwa 500, 850 kapena 100 mg, ndipo mankhwalawa amagwiritsidwa ntchito onse mu monotherapy komanso kuphatikiza ndi mankhwala ena.
Kodi ndingathe kumwa mapiritsi a kunenepa
Siofor yochepetsa thupi imatengedwa ndi anthu omwe amadziwa mphamvu ya mankhwalawa. Poyerekeza ndi ndemanga, kwa mwezi umodzi ena amatsika mpaka 10 kg yolemera kwambiri osagwiritsa ntchito zakudya zolimbitsa thupi komanso zolimbitsa thupi zolimbitsa thupi. Ngakhale kumwa mapiritsi ochepetsa chidwi, munthu amadya zopatsa mphamvu zochepa, kusiya mafuta ochulukirapo. Anthu omwe adagwiritsa ntchito mapiritsi awa amadya kuti amalakalaka chilichonse chokoma, ufa, kusowa, komanso kukopeka ndi zipatso ndi ndiwo zamasamba.
Njira yamachitidwe
Siofor imagwiritsidwa ntchito kwambiri kunenepa kwambiri chifukwa cha mphamvu ya mankhwalawo pazomwe zimachitika mu thupi. Kupatula apo, chifukwa cha kusowa kwa insulini, glucose sangalowe mu maselo pawokha, chifukwa chomwe shuga amawonjezeka. Ndipo ngati kudya zamafuta sikulephera, pakufunika kusuntha kwawo, ndipo thupi limayamba kupanga minofu ya adipose. Mafuta kawirikawiri amalepheretsa kupanga insulini, chifukwa, munthu amayamba kunenepa kwambiri.
Zotsatira zamankhwala a Siofor ndikuti mphamvu yake yogwira ntchito Metformin imayendetsa njira yopanga shuga, ndikuwonjezera chidwi cha zolandilira, ndikuchepetsa mayamwidwe obwera a chakudya. Njira yowotcha mafuta imachitika ndikuwonjezera kuchuluka kwamafuta acids ndikuwonjezera kuchuluka kwa mafuta a glycerol m'madzi am'magazi, omwe amalowa m'matumbo a minofu kuti agwiritse ntchito mafuta m'thupi.
Momwe mungatengere Siofor 500/8/10000 kwa kuwonda
Mu phukusi lililonse la Siofor mumakhala malangizo omwe kapangidwe kake kamankhwala, momwe amagwiritsidwira ntchito, nthawi ya kayendetsedwe (nthawi yayitali), mlingo wa tsiku ndi tsiku komanso njira yamankhwala imasonyezedwa. Dziwani kuti ichi ndi mankhwala amphamvu, ndipo musanamwe kumwa kuti muchepetse thupi, muyenera kufunsa dokotala kuti mupewe kuyipa.
Mapiritsi amatengedwa popanda kutafuna, kutsukidwa ndi madzi ambiri. Mlingowo umaperekedwa ndi adokotala, potengera kupezeka kwake, kuchuluka kwa kunenepa kwambiri komanso kulolerana ndi mankhwalawo. Poyamba, Siofor 500 imayikidwa kuti muchepetse kunenepa (muphunzira momwe mungayang'anire ndi kuwunikira omwe ataya thupi kuchokera kwa dokotala wanu). Mlingo wocheperako ndi piritsi limodzi patsiku, ndipo lalikulupo - 6 zidutswa, zomwe zidagawidwa pawiri. Mankhwalawa amachotsedwa mthupi ndi mkodzo pambuyo pa maola 6-7.
Mapiritsi Siofor 850 ndi mapiritsi Siofor 1000, malinga ndi zosungidwazo, amatengedwa, kuyambira chidutswa chimodzi patsiku, pang'onopang'ono kuwonjezera mlingo mpaka zidutswa zitatu usiku kapena mutatha kudya. Mankhwalawa am'mimba mtundu wa kunenepa kwambiri (mafuta pamimba), kuchuluka kwa mankhwalawa ndikotheka. Ndingamwe mankhwalawa mpaka liti, akatswiri okhawo anganene. Popanda kuonana ndi dokotala, simungathe kuwonjezera payekha payekha.
Kuyenderana ndi mowa
Mankhwala a Siofor ndi othandiza kuti muchepetse thupi, koma siabwino kwa anthu omwe ali ndi chidakwa. Pali malingaliro akuti kumwa zakumwa zoledzeretsa zopanda mafuta kumakhala ngati hypoglycemic, koma izi sizowona. Mowa sichizindikiro chakuchipatala chothandizira matenda aliwonse. M'malo mwake, madokotala amalimbikitsa kusiya kumwa kwambiri kwa iwo omwe akufuna kuchepa thupi, chifukwa, kuwonjezera kuzolowera, kumwa mopitirira muyeso, pakumwa mowa, kumafunikira chakudya, chomwe sichimakhala kashiamu ochepa.
Ponena za kumwa kwa mowa ndi Siofor kapena Siofor motalika, zotsatirapo zake zingakhale zosasintha. Mukamagwiritsidwa ntchito limodzi, mowa ungalepheretse kupanga kwa glucose ndikuwapangitsa kwambiri. Ngati mukufuna kuchepetsa thupi ndi Siofor, koma nthawi yomweyo mukuganizira kuchuluka kwa mowa, ndiye kuti muyenera kukana chilimbikitso chimodzi kapena chimzake. Chitetezo ndikofunika kwambiri kuposa zovuta ndi chithunzi.
Mitu ya mankhwalawa
Ngakhale ambiri a Siofor amadziwika kuti ndi chida chabwino kwambiri chochepetsera kunenepa pakati pa mankhwala, koma si aliyense amene angagwiritse ntchito mankhwalawa. Pali mwayi wonenepa thupi mothandizidwa ndi mankhwala monga:
Izi zomwe zimafanana ndi zamankhwala zimafanana ndi Siofor, koma pali zosiyana. Glformin ndi Formetin ndi njira ina yabwino kwambiri, chifukwa imakhudzanso thupi potaya thupi.
Siofor, glucophage kapena metformin - ndibwino ndi kusiyana kwanji?
Metformin ndi Glucofage zimagulitsidwa m'malo mwa Siofor. Ngati simukupeza mmodzi wa iwo mufamu, samalani ndi wina. Kusakwanira kwa mankhwalawa kumafotokozeredwa ndi zolakwa zokha pazakudya, kudya ndi kumwa, komanso kufunikira kophatikizana ndi mankhwala ena omwe angathandizire machitidwe a mankhwala antidiabetes.
Kodi Siofor 500/80/100000000 mumapiritsi ogulitsa mankhwala?
Kutengera komwe kuli mzindawu, mtengo wa Siofor m'masitolo azosiyanasiyana. Monga lamulo, kukulitsa kukhazikikako malinga ndi kuchuluka kwa anthu, kukwera mtengo. Chifukwa chake, ku Moscow, mtengo wa mankhwalawa udzakhala wokwera kwambiri, ndipo ngati mungayang'anire Siofor mufesi ya pa intaneti, ndiye kuti pali mwayi wopanga zotsika mtengo. Ndiye ndizowononga ndalama zingati kulongedza mankhwala omwe amadziwika kuti amachepetsa thupi?
- Mtengo Siofor 500 mg - 250-500 rubles.
- Mtengo Siofor 850 mg - 350-400 rubles.
- Mtengo Siofor 1000 mg - 450-500 rubles.
Chifukwa chiyani mankhwala nthawi zambiri amafanizira?
Glucophage ndi Siofor ndi mankhwala awiri omwe amagwiritsidwa ntchito nthawi zambiri kuchiza kunenepa kwambiri mwa anthu. Poyamba, mankhwalawa amangogwiritsidwa ntchito pochiza matenda a shuga a 2, koma posachedwa, mankhwalawa agwiritsidwa ntchito kwambiri pochiza kunenepa kwambiri. Chowonadi ndi chakuti kupangidwa kwa mankhwalawa kumaphatikizapo zinthu zapadera zomwe zimatha kupondereza chilakolako, chifukwa chake kumwa mankhwalawa kungakhale kothandiza kwambiri pochiza kunenepa kwambiri.
Potengera kapangidwe kake ndi mankhwala othandizira, mankhwalawa ndi ofanana kwambiri. Komabe, pali zosiyana zina pakati pawo, kotero palibe chodabwitsa chifukwa chakuti mankhwalawa amawafananizidwa nthawi zonse. Pansipa tikambirana za chithandizo cha mankhwala chilichonse, kenako tiona kuti ndi iti mwa mankhwala omwe ali othandiza kwambiri.
Kodi Siofor ndi chiyani?
Siofor ndi mankhwala a zinthu zingapo. Nthawi zambiri amagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga. Mankhwalawa samachiritsa matendawa kwathunthu, koma amangobwezeretsa khungu kwakanthawi, choncho munthu wodwala matenda a shuga ayenera kutenga Siofor moyo wake wonse. Mukagwiritsidwa ntchito, chinthu chachikulu chomwe chimagwira chimatulutsidwa nthawi yomweyo, ndipo zomwe zimatchulidwapo zimakhalapo.
Komanso, mankhwalawa amatha kugwiritsidwa ntchito pochiza zovuta zina. Kafukufuku akuwonetsa kuti kugwiritsidwa ntchito kwa Siofor kwa nthawi yayitali kumachotsa cholesterol m'thupi, motero mankhwalawa amatha kugwiritsidwa ntchito pochiza matenda amtima omwe amaoneka kuti akuwonekera kumbuyo kwa kuchuluka kwa cholesterol. Komanso, mapiritsi amatha kugwiritsidwa ntchito pakuchepetsa thupi.
Mu thupi, kuzungulira kwa satiety mwachindunji kumatengera kuchuluka kwa shuga. Ngati pali zochuluka kwambiri za izi, ndiye kuti munthuyo amamva njala. Nthawi yomweyo, kagayidwe kazakudya m'thupi kamakonzedwa m'njira yoti panthawi ya chakudya munthu azitha kumva ludzu kwakanthawi, komwe nthawi zambiri kumabweretsa kudya kwambiri. Chifukwa chamadya ochulukirapo, thupi limalandila zopatsa mphamvu zochulukirapo, zomwe zidzasinthidwa kukhala mafuta, zomwe zidzatsogolera kukulemera. Pankhani yovomerezedwa, ndende ya shuga imangotsika, zomwe zimapangitsa kuti muzimva kukomoka. Chifukwa cha izi, zimakhala zosavuta kuti munthu athe kulamula chakudya, ndipo kuchuluka kwa chakudya kumachepetsedwa. Kuchepetsa chakudya chama calorie kumabweretsa kuchuluka kwa kagayidwe ndi kuwotcha kwamafuta am'madzi, zomwe zimabweretsa kuwonda.
Siofor imapezeka mu piritsi. Mlingo ndi njira yogwiritsira ntchito mankhwalawa zimatengera magawo ambiri, komabe, nthawi zambiri amamwa mankhwalawa mapiritsi atatu katatu patsiku musanadye. Njira ngati imeneyi ndiyofunikira kuti muchepetse chilakolako chisanafike. Nthawi yomweyo, Siofor nthawi zambiri imayikidwa limodzi ndi mankhwala ena ochepetsa shuga, popeza Siofor imaphatikizana bwino ndi zinthu zambiri.
Mankhwalawa alibe zotsatira zoyipa mukamatsatira malamulo oyendetsera, koma ngati mukupezeka mankhwalawa, kusokonezeka monga nseru, kusanza, chizungulire, kupweteka kwa mutu, kupweteka m'mimba ndi zina. Mukafuna kumwa mankhwala osokoneza bongo, muyenera kusiya kumwa mankhwalawo ndi kufunsa dokotala kuti akuthandizeni (vuto la poizoni wambiri, mutha kuyimbira ambulansi). Palinso matenda omwe amamwa
- Chiwindi ndi matenda a impso
- Osakwana zaka 16
- Mavuto osiyanasiyana omwe amapanga insulini ali ndi vuto lililonse kapena pang'ono (mwachitsanzo, matenda amtundu 1),
- Mimba komanso kuyamwa
- Chitetezo chokwanira komanso / kapena hemoglobin wochepa m'magazi,
- Mowa
- Kulephera kwa mtima.
Chofunikira chachikulu
Tawona kale kuti onse mankhwalawa amatengera chinthu chofanana. Ndi metformin.
Chifukwa cha metformin, zinthu zotsatirazi zimachitika m'thupi la munthu:
- kuchuluka kwa khungu kumapangitsa insulini kumachepa
- mayamwidwe m'matumbo amachepetsa
- m'maselo a shuga amatha kukhala bwino.
Metformin, imangoyendetsa mayankho a maselo, siyimalimbikitsa kupanga yake insulin. Zotsatira zake, kusintha kwabwino kumachitika m'thupi la anthu odwala matenda ashuga. Carbohydrate metabolism imayamba kuyenda bwino.
Mlingo, nthawi ya ntchito ya mankhwala onse awiri imatsimikiziridwa ndi dokotala. Chifukwa chake, maziko a mankhwalawa amatha kukhala othandizira popanga nthawi yayitali. Zotsatira zochepetsera kuchuluka kwa shuga m'magazi pakatha nthawi yayitali zimatha.
Glucophage Wogwiritsa ntchito piritsi
Pankhaniyi, mawu oti "Kutalika" adzapezeka m'dzina lokonzekera. Mwachitsanzo: Mankhwala Glucophage Long amatenga kagayidwe kazakudya, ngakhale mlingo wa bilirubin m'magazi. Mankhwala oterowo adzafunika kumwedwa kamodzi patsiku.
Kusankha kwa mankhwala a shuga ndi vuto lalikulu. Magwiridwe ogwirira ntchito ndi zomwezi amagwira ntchito azofanana. Koma nthawi yomweyo tikuchita ndi mitundu iwiri yosiyanasiyana - Glucophage ndi Siofor.
Nthawi zina adotolo satchula dzina linalake, amangopereka mndandanda wazamankhwala. Anthu odwala matenda ashuga ayenera kusankha okha mankhwalawo pazokha. Kuti muchite izi, muyenera kumvetsetsa bwino kusiyana kulikonse pakati pa mankhwalawa.
Zotsatira zoyipa ndi contraindication
Zotsatira zoyipa za Siofor ndizocheperako, izi ndi monga:
- kutsegula m'mimba
- kusapeza bwino mwanjira yakung'ung'udza m'mimba,
- kutulutsa (zolimbitsa).
Zotsatira zingapo za matenda, momwe momwe Siofor imagwiritsidwira ntchito siikulimbikitsidwa. Izi zikuphatikiza:
- lembani matenda a shuga 1 mellitus (kunenepa kwambiri, mankhwalawo amaloledwa),
- ketoacidotic chikomokoma,
- Zomwe zili m'magazi ndi mkodzo wa mapuloteni a globulins, albin,
- matenda a chiwindi, kuchepa kwake kwa ntchito
- kusakwanira kwa mtima, mitsempha yamagazi,
- hemoglobin wochepa m'mwazi,
- chithandizo cha opaleshoni, kuvulala,
- Mimba, kuyamwa,
- kulephera kupuma
- uchidakwa
- wazaka 18
- kusowa kwa insulin, yomwe imapangidwa ndi kapamba (izi zitha kuchitika chifukwa cha matenda ashuga a 2),
- kugwiritsa ntchito njira zakulera zamkamwa, popeza kuphatikiza kwa mankhwalawa kumawonjezera mwayi wokhala ndi pakati osakonzekera,
- tsankho limodzi ndi zigawo zikuluzikulu za mankhwala.
Sikoyenera kugwiritsa ntchito mankhwalawa kwa anthu atatha zaka 60 ngati akuchita ntchito yayikulu.
Zotsatira zoyipa mukamagwiritsa ntchito Glucofage zimapezekanso. Izi zikuphatikiza:
- dyspepsia
- mutu
- chisangalalo
- malungo
- kutsegula m'mimba
- kufooka, kutopa.
Nthawi zambiri, zotsatirazi zimayamba chifukwa cha mankhwala osokoneza bongo omwe amakhalapo. Kuchokera pamimba, m'mimba mwake pamachitika zinthu zosafunikira ngati wodwalayo sakutsatira zakudya zamafuta ochepa.
Palinso ma contraindication angapo momwe kugwiritsa ntchito glucophage ndikosayenera kwambiri. Izi zikuphatikiza:
- mtundu 1 shuga
- Mimba, kuyamwa,
- kuchira pambuyo opaleshoni, kuvulala,
- matenda a mtima
- uchidakwa wambiri,
- matenda a impso
- kusalolera payekha mankhwala.
Glucophage kapena Siofor
Zotsatira za chithandizo cha matenda ashuga amtundu wachiwiri zimatengera mawonekedwe a thupi la wodwalayo.
Mndandanda wazotsatira zoyipa ku Glucofage ndizitali. Mwinanso pachifukwa ichi, ambiri odwala matenda ashuga amasankha Siofor wamba.
Koma chomaliza chimadziwika ndi kuchuluka kwakukulu kwa contraindication, motero odwala amakakamizidwa kutenga Glucofage.
Ponena za izi, ndikofunikira kusankha mankhwala omwe ali ndi dzina pomwe mawu oti "Long" alipo. Nthawi zambiri imakhazikitsidwa kamodzi patsiku, ndiye kuti sizowopsa m'matumbo.
Kodi Glucophage ndi chiyani?
Glucophage lilinso mankhwala opangidwa ndi metformin omwe amagwiritsidwanso ntchito pochiza matenda a shuga a 2. Mankhwalawa amathanso kugwiritsidwa ntchito pochiza zovuta zina, mwachitsanzo, kuchiza kunenepa kwambiri. Chomwe chimasiyanitsa Glucophage ndichakuti kapangidwe kake ka mankhwalawa kamaphatikizapo ambiri opeza. Chifukwa cha izi, zomwe zimadziwika kuti zimatenga nthawi yayitali zimatheka - pambuyo pa makonzedwe, metformin samamasulidwa nthawi yomweyo (monga momwe zimachitikira ndi Siofor yemweyo), koma pang'onopang'ono kupitirira maola 10-12.
Chifukwa chake, Glucofage imatha kuledzera pafupipafupi. Glucophage nthawi zambiri amalembera zochizira matenda amitundu iwiri, koma mankhwalawa amathanso kugwiritsidwa ntchito pochiza kunenepa kwambiri. Kafukufuku akuwonetsa kuti mothandizidwa ndi Glucofage, muthanso kutaya pafupifupi 1-3 kg pa sabata. Popeza Glucofage imakhala ndi mphamvu yayitali, mutha kumwa piritsi limodzi kawiri pa tsiku, mosasamala nthawi yakudya. Komabe, muyenera kumwa mankhwalawa maola aliwonse 12, popeza nthawi yayitali imatha ndi nthawi, chifukwa chake, ngati kuphwanya malamulo ovomerezeka, kuchuluka kwa shuga mwa munthu kumatha kuchuluka, zomwe zimapangitsa kuti mukhale ndi chidwi chambiri.
Kupanda kutero, Glucofage ndi yofanana kwambiri ndi mankhwala ena onse okhala ndi metformin. Kuthana ndi kunenepa kwambiri, simuyenera kungomwa Glucofage, komanso kutsatira moyo wathanzi, chifukwa mwinanso magwiridwe antchito azamankhwala amakhala otsika kwambiri. Glucofage ilibe zotsatira zoyipa ngati malamulo a muyeso amatsatiridwa ndikuyenda bwino ndi mankhwala ena kuti muchepetse shuga. Komabe, mankhwalawa amaphatikizidwa pazochitika zotsatirazi:
- Mtundu woyamba wa matenda ashuga ndi matenda ena onse omwe mumaphwanya insulin,
- Impso ndi chiwindi
- Matenda a mtima
- Mowa
- Mimba komanso kuyamwa
- Zaka mpaka 16.
Ndi mankhwala ati omwe ali bwino?
Monga mukuwonera, mankhwalawa ndi ofanana kwambiri wina ndi mnzake pakapangidwe kake ndikuchiritsira thupi. Mankhwalawa amagwiritsidwa ntchito pochiza matenda amishuga amtundu wa 2, koma chifukwa chochepetsera kuchuluka kwa shuga m'magazi, mankhwalawa atha kugwiritsidwa ntchito ngati chilakolako chofuna kudya, chomwe chingakhale chothandiza pochotsa kunenepa kwambiri. Kugwiritsa ntchito bwino kwa mankhwalawa ndi chimodzimodzi - ndi thandizo lawo mutha kutaya 1-3 kg pa sabata, ngati mumadya moyenera, masewera olimbitsa thupi komanso osakhala ndi zizolowezi zoyipa. Mankhwala onse awiriwa ali ndi zotsutsana, zotsatira zoyipa, komanso zimagwirizana ndi mankhwala ena.
Komabe pochita, madokotala nthawi zambiri amakonda Glucophage. Ndipo chifukwa chake:
- Pochiza kunenepa, ndikofunikira kwambiri kuti muchepetse chidwi cha munthu, chifukwa anthu ambiri amasiya kudya zakudya zamagulu chifukwa amakhala ndi njala atatha kudya chakudya.
- Kuti athane ndi vuto la kudya, dokotala atha kukupatsirani mankhwala kuti muchepetse shuga, chifukwa amatha kuletsa nkhawa, yomwe imalola munthu kuti azilamulira zakudya.
- Ndikofunika kumvetsetsa kuti glucophage chifukwa cha zowonjezera zimakhudza nthawi yayitali, ndipo kulakalaka kumachepa ndi maola 10-12 mutatha kumwa mankhwalawo.
- Siofor amalandidwa mwayiwu, womwe umachepetsa chilimbikitso pokhapokha pambuyo pa makonzedwe, ndipo patatha mphindi 20-30 mphamvu yoleketsa chilala imatha.
- Chifukwa chake, ndikosavuta kwa munthu kumwa Glucofage kawiri pa tsiku, mosasamala nthawi yakudya, kuposa kumwa Siofor kangapo musanadye.
- Ichi ndichifukwa chake Glyukofazh pa avareji amapatsidwa mankhwala ochulukirapo kuposa Siofor. Komabe, ziyenera kumvetsedwa kuti Siofor ndiwonso mankhwala abwino kwambiri opondaponda - siwotsekanso kumwa, koma mukamatsatira malamulo oyendetsera, zotsatirapo zochizira ndizofanana.
Siofor kapena Glucophage - madokotala ndi odwala akuganiza chiyani?
Tiyeni tsopano tidziwe zomwe odwala wamba komanso madokotala odziwa amaganiza pakugwiritsa ntchito Siofor ndi Glucofage.
Anton Verbitsky, wothandizira zakudya
“Ngati munthu adya kwambiri, kenako nkudya mwadzidzidzi, ndiye kuti zimamuvuta. Nthawi yomweyo, zimamuvuta, ngakhale pakudya zomwe zikusonyeza kuti nthawi yasintha, munthu akatha kudya zakudya zomwe sakudziwa. Vuto lalikulu silikhala mu chakudya (pambuyo pa zonse, nthawi zambiri sizovuta kwenikweni kupanga mapulani azakudya), koma vuto la kulakalaka kwambiri, chifukwa ndizovuta kwambiri kuti munthu athe kupeza chakudya chokwanira. Mwamwayi, masiku ano pali kuchuluka kwa mankhwalawa kuti muchepetse kulakalaka. Nthawi zambiri ndimapereka mankhwala a Glucophage kwa odwala anga, chifukwa ndi othandiza kwa maola 12, motero ndikokwanira kuti munthu azitha kudya piritsi limodzi m'mawa komanso piritsi limodzi madzulo kuti athane ndi vuto lakelo. Komabe, pankhani ya kunenepa kwambiri, nditha kukupatsani mankhwala ena owonjezera a piritsi limodzi la Siofor, lomwe silikhala ndi nthawi yayitali, koma lomwe limachepetsa kuchuluka kwa shuga mthupi, zomwe zimapangitsa kuti munthu amene ali ndi kunenepa kwambiri apirire.
Antonina Petrova, wopuma pantchito
“Ndili ndi zaka 70, ndinayamba kukhala ndi vuto la shuga. Chifukwa cha shuga wambiri, ndinakhalanso wonenepa kwambiri. Dotolo adayamba kupangira Siofor, kuti ndimwera piritsi limodzi musanadye. Kwa masabata awiri ndidataya pafupifupi 5 kg kwinakwake. Komabe, sindinkakhala bwino ndimamwa mankhwalawa musanadye chilichonse - ndipo ndinamuuza dotolo za izi. Adotolo, ndikuganiza, adandipatsa mankhwala otchedwa Glucofage m'malo mwa Siofor. Ndinkamwanso kwa masabata awiri m'mawa nditadzuka komanso madzulo ndisanadye. Ndipo nthawi imeneyi ndidatayanso 5 kg. Zikuwoneka kuti chithandizo cha mankhwalawa ndichofanana, koma Glucophage akadali yosavuta kumwa. ”
Peter Alekseev, wogwira ntchito
“Nditasamukira ku malo ena ochitira masewera olimbitsa thupi, thupi langa linachepa. Chifukwa cha izi, ndinayamba kuwoneka wonenepa kwambiri. Poyamba ndinayesera kusintha ndekha chakudya, koma palibe chabwino chomwe chidabwera. Kenako ndinapita kwa katswiri wazakudya. Anandipangira dongosolo lazakudya, zomwe ndimayenera kuzichepera pafupifupi 8-9 kg pamwezi. Komabe, zoletsa pazakudya zinali zazikulu kwambiri kotero sindinathe kukhala pachakudya ichi kwakanthawi. Adotolo atazindikira kuti ndasiya kudya, adandiuza kuti Glucofage ndiyenera kudya. Ndipo mukudziwa, zinathandiza. Kumwa mankhwalawa ndikosavuta, ndipo zotsatira zake zimangowonekera maola awiri atatha Tithokoza kwambiri adotolo. ”
Pomaliza
Mwachidule. Glucophage ndi Siofor ali ndi mawonekedwe ofanana, kotero mankhwalawa ali ndi njira yofanana yochizira. Komabe, Glucophage imakhala ndi mphamvu yayitali, pomwe Siofor amakanidwa izi, chifukwa chake Glucophage imayikidwa pafupipafupi. Tiyenera kumvetsetsa kuti m'njira zina zonse mankhwalawa ndi ofanana kwambiri. Amachepetsa kulakalaka bwino, motero amagwiritsidwanso ntchito pochiritsa kunenepa kwambiri.
Mothandizidwa ndi mapiritsi, mutha kutaya 1-3 makilogalamu pa sabata ngati mutsatira malamulo a mlingo. Mankhwalawa amaphatikizidwa bwino, komabe, amatsutsana mu matenda ena komanso panthawi yomwe ali ndi pakati.
Malingaliro a akatswiri azakudya pazovuta zamankhwala
Malingaliro a akatswiri azakudya zokhudzana ndi kugwiritsa ntchito Siofor pakuchepetsa thupi ndi mawonekedwe ake adagawika m'magulu awiri. Ena amati kuyerekezera pang'ono kumapereka zakudya zoyenera mwachangu, ndipo mankhwalawo amayenera kugwiritsidwa ntchito pokhapokha ngati kunenepa kwambiri. Ena samatsutsana ndi kugwiritsa ntchito mankhwala ochepetsa mphamvu ya shuga ngati chotseketsa, koma pokhapokha atatha kuwunika mwazomwe amachita.
Kuonda Kwambiri Kunenepa ndi Zotsatira
Unikani Na. 1
Zaka zitatu zapitazo, ndidakhala bwino kwambiri kuti sinditha kuwona zithunzi za nthawi imeneyo. Ndinawerenga ndemanga pa intaneti, ndikukonzekera kumwa Siofor 500. Poyamba sindinasangalale ndi zomwe zimachitika mthupi: nseru idawoneka, koma tsiku lachitatu idapita. Ndataya makilogalamu 12 pa maphunziro onse.
Unikani Na. 2
Siofor adayesedwa kuti achepetse magazi a shuga, chifukwa ndili ndi matenda ashuga. Sindinadziwe kuti mankhwalawo anali otani komanso momwe amagwirira ntchito, koma zomwe zidandidabwitsa pomwe kulemera kunayamba kuchepa koma mosachedwa kutsika. Ndataya makilogalamu 5 pamwezi "
Unikani Na. 3
Nditasiya kusuta, ndinayamba bwino, motero ndinasankha kuchepetsa thupithandizo la Siofor. Zowona, ndidali kudya zakudya zopatsa mphamvu kwa miyezi isanu ndi umodzi, chifukwa zotsatira zake sizinatenge nthawi - minus 10 kg ”
Siofor kapena Metformin
Mankhwala onse awiriwa ali ndi chinthu chimodzi chogwira ntchito. Zomwe mungakonde zili kwa wodwala. Apanso, Siofor ali ndi mndandanda wautali wa zotsutsana.
Metformin ili ndi mndandanda wachidule wa zotsutsana:
- matenda a m'mapapo,
- Matenda a chiwindi, impso,
- myocardial infaration
- kuphwanya zakudya kagayidwe kachakudya chifukwa cha kusowa kwa insulin,
- zaka mpaka 15
- zigawenga
- matenda oopsa
- malungo
- poyizoni
- kugwedeza.
Makanema okhudzana nawo
Kuwunika mwachidule kukonzekera kwa Siofor ndi Glucofage mu kanemayo:
Pofuna kuti musalakwitsa posankha mankhwala ochizira matenda amtundu wa 2, ndikofunikira kuphunzira mosamala zotsutsana, zoyipa. Liwu lomaliza liyenera kukhala la adokotala. Koma ngati dokotala akuwonetsa kusankha, mutengere mozama.
- Imakhazikika pamisempha ya shuga kwa nthawi yayitali
- Imabwezeretsa kapangidwe ka insulin
Phunzirani zambiri. Osati mankhwala. ->