Ma analogi otchuka komanso otsika mtengo a Roxer

Ma statin amakono akhala gawo limodzi la chithandizo chachikulu kapena chophatikiza cha matenda oopsa - hypercholesterolemia, i.e., okwera kwambiri a cholesterol m'magazi, omwe sangathe kuwongoleredwa ndi njira zosagwiritsa ntchito mankhwala kwa nthawi yayitali.

Chimodzi mwazina za mankhwalawa ndi Roxer: zimawerengedwa ndi akatswiri amtima ambiri kuti azichita bwino komanso chitetezo. Ngati wodwala alibe mwayi wogula, mutha kugula mankhwala omwe ali pafupi momwe angapangidwire kapangidwe kake kapena kagwiritsidwe kake ka thupi - analogues.

Zambiri pazamankhwala ndi malangizo ogwiritsira ntchito

Roxera (Roxera) - mankhwala ozikidwa pa rosuvastatin (IV m'badwo wama statins) kuchokera ku kampani yaku East Europe KPKA (KRKA), Slovenia.

Zisonyezero zogwiritsidwa ntchito zimaphatikizapo mitundu yosiyanasiyana ya dyslipidemia ndi hypercholesterolemia, komanso atherosulinosis ndi zina matenda a mtima.

Kuchita kwa ma statins kumakhazikitsidwa ndi cholepheretsa enzyme, yomwe imayang'anira kupanga cholesterol ndi chiwindi (gwero la pafupifupi 80% ya chinthucho).

Kuchulukitsa kwa lipid kumawonekera pakusintha kwa chiŵerengero cha "zoyipa" (LDL, LDL) ndi "chabwino" (VLDL, HDL) plasma lipoproteins. Ntchito ya pharmacological imatchulidwira m'chiwindi, pomwe rosuvastatin imalepheretsa HMG-KoA-Reductase, enzyme yomwe imathandizira kapangidwe ka cholesterol (Chol, XC).

Kuphatikiza apo, Roxer amathandizanso kutupa kosafunikira, chomwe ndi chimodzi mwazifukwa zazikulu zopangira cholesterol malo, ndikuwathandizanso kupanga nitric oxide, yomwe imathandizira kuti mitsempha ya magazi ikhale yopuma, zomwe zimapangitsa kuti antiatherosseloticotic ichitike.

Kutulutsa mawonekedwe - mapiritsi ozungulira (ozungulira kapena chowulungika) okhala ndi 5, 10, 15, 20, 30 kapena 40 mg wa rosuvastatin, wokutidwa ndi nembanimu yoyera.

Mankhwala amatengedwa pakamwa nthawi iliyonse ya tsiku. Mlingo woyambirira wa 5 mg patsiku, pakalibe mphamvu zazikulu, umakwera 10 mg.

Zotsatira zake zimadziwika pambuyo masiku 7- 9 mutatenga Roxer, koma zimatenga masabata 4-6 kuti mupeze zotsatira zabwino. Pafupifupi, kuchuluka kwa cholesterol yonse kumachepa ndi 47-55%, lipoproteins wotsika - mwa 42-65%, ndipo zomwe ma lipoproteins apamwamba akuwonjezeka ndi 8-14%.

Ma analogi odziwika kwambiri ndi oyimilira a Roxers

Zofananira ndi cholowa m'malo mwa ma Roxers amatchedwa "ma syonyms" kapena "ma generics" - mankhwala omwe amasinthika muzochita zawo potengera zomwe zikuchitika. Amasiyana ndi kakulidwe koyamba pakupanga tekinoloje, dzina lamalonda ndi kuchuluka kwa zina zowonjezera.

Popeza kutha kwa mankhwalawa, monga lamulo, sikotsika poyerekeza ndi koyambirira, wodwalayo ali ndi ufulu wosankha generic yovomerezeka, kuyang'ana kwambiri pa tsankho, bajeti kapena zina zomwe amakonda. Chachikulu ndikuyang'anira kuchuluka kwa mankhwala omwe adokotala adalandira ndi mawonekedwe ake a mankhwalawo.

Mertenil (Mertenil) - imodzi mwazifanizo za Roxers. Amasiyanitsidwa ndi muyeso wapamwamba kwambiri wa kuyeretsa komwe kumagwira ntchito, komwe kumathandizira kulolerana kwake kwabwino ngakhale ndikugwiritsa ntchito nthawi yayitali. Mwakutero, Mertenil nthawi zambiri amagwiritsidwa ntchito pochiza odwala okalamba komanso ochepa.

Zomwe zimapangidwira: Ndiwofanana mu chilichonse kuyambira pachiyambi, kupatula utoto.

Kampani, dziko loyambira: Gedeon Richter, Hungary.

Mtengo wongoyerekeza: kuchokera 487 RUB / 30 ma PC 5 mg mpaka 1436 rubles / 30 ma PC. 40 mg

Rosuvastatin-SZ

Rosuvastatin-C3 (Rosuvastatin-SZ) ndi analogue wotsika mtengo wa ma roxers opangidwa m'nyumba. Ili ndi gawo lofanana la rosuvastatin monga loyambirira, koma limasiyana pang'ono mu kuchuluka kwa zinthu zothandizira, zomwe zimapangitsa kukhala mankhwala osagwirizana mwachangu komanso mwachangu.

Zomwe zimapangidwira: ili ndi soya lecithin ndi aluminium varnish wamitundu itatu.

Kampani, dziko loyambira: FC Northern Star 3AO, Russia

Mtengo wongoyerekeza: kuyambira 162 p / 30 ma PC. 5 mg mpaka 679 p. / 30 ma PC. 40 mg

Crestor (Crestor) - mankhwala oyamba kuchokera ku rosuvastatin, omwe ndi okwera mtengo kwambiri kuposa ma analogues. Amapukusidwa pang'ono mu chiwindi (chochepera 10%), chomwe chimachepetsa kwambiri zovuta zamthupi - izi zimatsimikiziridwa ndi ndemanga zambiri za odwala.

Zomwe zimapangidwira: njira yoyambira patent.

Kampani, dziko loyambira: Astra Zeneca, England.

Mtengo wongoyerekeza: kuyambira 1685 mpaka 5162 rubles.

Rosart ndiye m'malo mwa Roxers. Mankhwala samayambitsa zotsatira zoyipa za thupi, chifukwa zonse zomwe zimagwira ntchito ndi zothandiza zimatsukidwa. Ndiye kuti, analogue ili ndi zabwino zonse za choyambirira ndipo nthawi yomweyo imakhala yotsika mtengo kuposa iyo.

Zomwe zimapangidwira: kapangidwe kamayenderana ndi choyambirira kupatula utoto.

Kampani, dziko loyambira: Gulu la Actavis, Iceland.

Mtengo wongoyerekeza: kuchokera 422 rub. / 30 ma PC. 5 mg mpaka 1318 rubles / 30 ma PC. 40 mg

Suvardio ndi mankhwala ena a ku Slovenia. Ku Russia, imaperekedwa mu assortment yochepa - 10 ndi 20 mg yokha, zomwe zimapangitsa kuti ikhale njira yosayenera yoyambira, chifukwa, kuti mupewe Mlingo wolakwika, osavomerezeka kugawa mapiritsi okhala ndi rosuvastatin m'magawo.

Zomwe zimapangidwira: kutengera ndi wowuma chimanga.

Kampani, dziko loyambira: Sandoz, Slovenia.

Mtengo wongoyerekeza: kuchokera 382 mpaka 649 rubles.

Mankhwala omwewo malinga ndi chinthu china chogwira ntchito

Ngati ndi kotheka, mwachitsanzo, hypersensitivity to rosuvastatin, mutha kusintha m'malo mwa Roxer ndi mankhwala ofanana, koma motengera chinthu china - pitavastatin. Kusintha koteroko sikungachitike mwa iwo okha, chifukwa mankhwalawa komanso mlingo wake ndi wosiyana kwambiri.

Livazo (Livazo) - mankhwala oyamba ndi pitavastatin. Mankhwala atsopanowa amadziwika ndi bioavailability woposa 51% komanso omanga ma protein a plasma opitilira 99%, ndichifukwa chake amakhala ndi mphamvu ngakhale yolingana ndi Mlingo wochepa komanso chiwindi.

Zomwe zimapangidwiraili ndi lactose, monga ma statin ena ambiri.

Kampani, dziko loyambira: Recordati, Ireland

Mtengo wongoyerekeza: kuchokera 584 RUB / 28 ma PC 1 mg mpaka 1244 rubles / 28 ma PC. 4 mg

Mtengo Wophatikiza Mtengo

Kuti tiyerekeze mtengo wamankhwala, mndandanda womwe umapangidwira umaphatikizapo okhawo omwe ali nawo pafupi a Roxer mu kuchuluka kokwanira kuchititsa maphunziro ochepa (masiku 28-30) - panthawiyi, monga lamulo, ndikokwanira kuti azindikire mphamvu ya mayankhidwe othandizira.

Compfukom'maloizileiRoxerspafupifupitoimoSTI(tebulo):

Dzina ndi mlingo wa mankhwala	Chiwerengero cha mapiritsi	Mtengo pa paketi iliyonse, pakani.
Rosuvastatin - 10 mg
Roxera (Roxera)	30	438–465
Mertenil (Mertenil)	30	539–663
Rosuvastatin-C3 (Rosuvastatin-SZ)	30	347–411
Crestor	28	1845–2401
Rosart	30	527–596
Suvardio	28	539–663
Pitavastatin - 1 mg
Livazo	28	612–684

Analogue yotsika mtengo kwambiri ya Roxer ndi Russia Rosuvastatin-C3, yomwe imapezeka kwa ogula ambiri. Komabe, posankha mankhwala, ndikofunikira kuganizira osati mtengo wawo wokha, komanso dziko lopanga (makamaka Europe), komanso mbiri ya kampani yopanga mankhwala.

Atoris kapena Roxer: zili bwino ndi chiyani?

Atoris (Atoris) ndi genor wa atorvastatin, wa m'badwo wa III wa gulu la statins.

Pakugwiritsa ntchito bwino, imakhala yofanana ndi mankhwala a Roxer, koma yachiwiri imachita zinthu modekha, imakhala ndi zovuta zochepa ndipo kawirikawiri thupi limasavuta kuzolowera.

Kuphatikiza apo, mapiritsi a Roxer samaletsa chiwindi kugwira ntchito kwambiri monga mibadwo yam'mbuyo, koma kugwiritsa ntchito nthawi yayitali kumatha kukulitsa vuto la impso, makamaka ngati wodwalayo anali kale ndi vuto la kwamikodzo. Chifukwa chake, nthawi zina adokotala amakondabe Atoris.

Koti mugule ndi anzanu a Roxer?

Mutha kugula mankhwala a Roxer kapena kusinthanitsa ndi mankhwala ena aliwonse akuluakulu pa intaneti:

• https://apteka.ru - Roxera No. 30 kwa 10 mg 436 rubles., Rosuvastatin-C3 No. 30 kwa 10 mg 315 rubles., Atoris No. 30 kwa 10 mg 312 rubles., Livazo No. 28 kwa 1 mg 519 rubles.,
• https://piluli.ru - Roxer No. 30 kwa 10 mg 498 rubles, Rosuvastatin-C3 No. 30 kwa 10 mg 352 rubles, Atoris No. 30 kwa 10 mg 349 rubles, Livazo No. 28 kwa 1 mg 642 rubles.

Mukulikulu, Roxerra analogues amagulitsidwa m'mafakitala ambiri apafupi:

• Kukambirana, st. 6 Kozhukhovskaya, d. 13 kuyambira 08:00 mpaka 23:00, tel. +7 (495) 108-17–25,
• Rigla, St. B. Polyanka, d. 4-10 kuyambira 08:00 mpaka 22:00, tel. +7 (495) 231-16-97.

Ku St. Petersburg

Ku St. Petersburg, mankhwalawa amapezekanso ku malo ogulitsa maulendo atali:

• ZdravCity, st. Zvezdnaya, d 16 kuyambira 9:00 mpaka 21:00, tel. +7 (981) 800-41-32,
• Ozerki, St. Michurinskaya, d. 21 kuyambira 08:00 mpaka 22:00, tel. +7 (812) 603-00-00.

Pomaliza, ndikofunikira kudziwa kuti chithandizo ndi ma statins aliwonse, kuphatikiza mapiritsi a Roxer, amachitidwa motsutsana ndi maziko a kuchira kwathunthu kwa thupi: zakudya za cholesterol, masewera olimbitsa thupi, kugona mokwanira komanso, ngati zingatheke, kupewa mavuto osokoneza.

Kodi rosucard kapena roxer wabwinoko ndi chiani?

Mankhwala a Rosucard ndi njira yothanirana ndi nkhondo yolimbana ndi cholesterol yayikulu, yomwe ingasokoneze zochita za mtima. Rosucard imapezeka mu mawonekedwe am'mapiritsi a pakamwa. Zomwe zimagwirira ntchito ndi rosuvastatin. Mankhwalawa amaperekedwa kwa odwala omwe ali ndi:

• mitundu yosiyanasiyana ya hypertriglyceridemia,
• atherosulinosis,
• hypercholesterolemia.

Chifukwa cha kumwa mankhwalawa, njira yotsatsira imatheka:

• mtima ischemia
• myocardial infaration
• zovuta zina zamtima ntchito.

Rosucard imawonedwa kuti ndi chofanizira cha Roxer, ngakhale ili ndi zina zapadera. Malangizo ogwiritsira ntchito Rosucard amatsimikizira kuchepa kwa cholesterol m'thupi kwa masiku 5 kuyambira nthawi yoyang'anira. Mapiritsi a Roxer amawonetsa zotere pokhapokha patsiku la 10.

Mapiritsi omwe amafotokozedwawo amatha kuyambitsa zovuta mu mawonekedwe a shuga. Kukonzekera kwa Roxer sikupereka chithunzi chotere. Rosucard sizitsogolera kuti mawonekedwe azapuloteni apezeka mkati mwamthupi, mosiyana ndi wotsutsana naye.

Wopanga Rosucard amalimbikitsa kumwa mankhwalawa ndi zaka 15 moyang'aniridwa ndi dokotala wothandizira. Roxer iyenera kugwiritsidwa ntchito ndi anthu azaka zapakati pa 18, chifukwa mapiritsi awa amakhudza ntchito ya chiwindi. Mtengo wa Roxer m'masitolo ogulitsa mankhwala ndi 1676 rubles, ndipo mitengo ya Rosucard simaposa ma ruble 600.

Kodi kuposa Roxer kapena Crestor ndi chiyani?

Krestor ndi yemweyo m'malo mwa Roxer. Mphamvu zake zotsitsa lipid zimatha kuchepetsa kuchuluka kwa cholesterol kuti ikhale yabwino kwambiri kwa thupi. Pulogalamu yayikulu yogwira ndi rosuvastatin. Zowonjezera zothandizira pazomwe zafotokozedwazo zimawonekera pakatha sabata, ndipo phindu lalikulu - pakatha mwezi wa kalendala.

Analogue iyi ya Roxer imachotsedwa m'thupi ndi ndowe. Zisonyezo pakugwiritsa ntchito:

• kupitilira kwa atherosulinosis,
• pulayimale Fredrickson hypercholesterolemia,
• hypertriglyceridemia,
• mabanja homozygous hypercholesterolemia.

Pogwiritsa ntchito nthawi yomweyo Krestor ndi mankhwala ena, wodwalayo adamulamula kuti azidyetsa zakudya zochepa. Zoyipirana ndi Crestor ndi:

• kuchuluka kwa chidwi chomva thupi,
• kulimbitsa thupi kwa zinyenyeswazi,
• Nthawi yonyamula mkaka
• matenda a impso
• kuukira kwa myopathy.

Mutha kumwa mapiritsi ofotokozedwa nthawi ina iliyonse patsiku, mosasamala chakudya. Krestor amatha kupangitsa chitukuko cha matenda osokoneza bongo a mtundu wachiwiri, omwe siamtundu wa mapiritsi a Roxer. M'mafakitala, analog ya Roxer yomwe idafotokozedwa imagulitsidwa pa ruble 720 pakiti iliyonse. Kuunika kwamankhwala ambiri kumatsimikizira kuthandizira kwa mankhwalawa, motero kusankha mokomera aliyense kuyenera kuchitika mothandizidwa ndi dokotala.

Yotsimikizika

Mapiritsi a Atorvastatin amaphatikizidwa m'gulu la otchipa a Roxer analogues. Amapangidwa ndi ma molekyulu a atorvastatin-calcium trihydrate ophatikizika ndi zovuta zina. Mankhwalawa amadziwika kuti ndi hypolipidemic statin. Komanso, analogue yofotokozedwayo imakhudza bwino mkhalidwe wa atheroma ndi mtsempha wamagazi. Zomwe zimapangidwa nthawi zonse, zikagwiritsidwa pafupipafupi, zimawonetsa antiproliferative ndi antioxidant katundu, kukonza masinthidwe aminyewa yamagazi.

Tithokoze Atorvastatin, kuchuluka kwa cholesterol kumachepetsedwa mwa omwe ali mu gulu la "homozygous Famel hypercholesterolemia", omwe sangatheke ndi mankhwala ena a hypolipidemic. Zisonyezero zogwiritsidwa ntchito:

• endo native hypertriglyceridemia,
• hypercholesterolemia yoyamba,
• kuphatikiza "kophatikizidwa" hyperlipidemia.

Mapiritsi a Atorvastatin amatengedwa pakamwa pakamwa, limodzi ndi zakudya zapadera. Zotsatira zabwino za mankhwalawa zimatheka tsiku lakhumi ndi chisanu kuyambira nthawi yakuvomerezedwa. Sitikulimbikitsidwa kumwa analogue yomwe ili ndi anthu omwe:

• Matenda olimbitsa thupi komanso oopsa a hepatic,
• Hypersensitivity kuti atorvastatin,
• ana ochepera zaka 18
• azimayi oyembekezera
• pa siteji ya mkaka,
• osati njira yodalirika yolerera pakubala.

Anthu omwe ali ndi vuto losakwanira hepatic amalimbikitsidwa kumwa Atorvastatin mosamala kwambiri, kuwunika zisonyezo zoyenera. Ngati matenda atayamba kupita patsogolo, ndiye kuti mankhwalawo ndi mankhwala ayenera kusiyidwa. Kugwiritsa ntchito nthawi yomweyo ziletso, zomwe zikufotokozedwa ndi mowa ndizowononga thanzi!

Zotsatira zoyipa pamakonzedwe awa ndi:

• minofu kukokana
• myositis
• achina,
• hyperglycemia
• kapamba
• chiwindi
• kusabala.

Mtengo wapakati wamapiritsi ndi ma ruble 112.

Kutengera ndi zomwe tafotokozazi, zitha kutsimikizika za zabwino za kumwa mapiritsi a Atorvastatin ndi Roxer.

Atoris ndi imodzi mwazotchuka zotsika mtengo kwambiri. M'mafakitala, mtengo wa Roxer ndi osachepera 1650 rubles, ndi Atoris - 350 rubles.

Chofunikira chachikulu cha mankhwalawo ndi mamolekyulu a rosuvastatin. Mankhwalawa ndi piritsi yokhala ndi zokutira zowonekera.

Zotsatira zabwino za mankhwalawa zimadziwika kumapeto kwa sabata lachiwiri la mankhwala ndi analog. Nthawi yomweyo, chizolowezi chowoneka ngati zovuta za ischemic chimachepetsedwa kwambiri.

Mosiyana ndi mankhwala Roxer, Atoris amalembedwa kwa anthu omwe akudwala:

• Hyperlipidemia:
• hypercholesterolemia yoyamba,
• kuphatikiza (kusakaniza) hyperlipidemia,
• dysbetalipoproteinemia,
• mabanja amkati hypertriglyceridemia.

Atoris angagwiritsidwe ntchito ngati prophylactic mankhwala ena a mtima matenda. Kuti mupewe chiopsezo chokhala ndi zotulukapo zoyipa, ma analogue awa sayenera kuledzera ndi kupita patsogolo mthupi:

• hepatic matenda enaake,
• Hypersensitivity kapangidwe kazinthu,
• matenda a chiwindi
• kulephera kwa chiwindi
• matenda a minofu.

Pofuna kupewa kutulutsa zotsatira zoyipa ndi zotsatira zoyipa, Atoris sayenera kumwedwa panthawi ya gestation komanso poyamwitsa. Pofuna kuti musawononge maselo a chiwindi chaching'ono, analog sayenera kuperekedwa kwa ana osakwana zaka 18.

Mapiritsi okhala ndi mafilimu amaikidwa pachilime ndikusambitsidwa pansi ndi madzi pang'ono. Mutha kuchita izi musanadye kapena pambuyo pake.

Rosuvastatin

Mtengo wapakati wa Rosuvastatin ndi ma ruble 138. Piritsi lililonse limakhala ndi calcium rosuvastatin, ndende yozama kwambiri. Pofuna kupewa kuchuluka kwa madzi a m'magazi a munthu m'magazi, mankhwalawo akuyenera kutengedwa ndi:

• mabanja homozygous hypercholesterolemia,
• hypercholesterolemia (mtundu IIa).

Contraindicated odwala ndi aimpso kulephera.Rosuvastatin sayenera kuledzera ndi:

• Hypersensitivity thupi mawonekedwe ake,
• matenda a chiwindi
• myopathies
• yoyamwitsa
• mimba iliyonse trimester,
• osafika zaka 18.

Rosuvastatin sayenera kutengedwa kwa azimayi amsinkhu wobereka pogwiritsa ntchito njira zodalirika zakulera. Pafupipafupi pa kayendetsedwe ndi mlingo wake amatsimikiziridwa ndi dokotala aliyense payekhapayekha kapena amalimbikitsa kuti azitsatira zomwe zaperekedwa.

Mankhwalawa amatha kupezeka pamsika pamtengo wa ma ruble 420. pa paketi iliyonse. Zomwe zimagwiritsidwa ntchito ndi mankhwalawa ndi mamolekyulu a calcium rosuvastatin. Amapangidwa m'mapiritsi ku Slovenia.

Suvardio amatsitsa cholesterol ndi zinthu zomwe amapanga m'magazi. Amachotsedwa m'thupi ndi chiwindi, ndipo ndimatenda ake, mankhwalawo amayenera kumwa mosamala kwambiri. Wolemba:

• Hypersensitivity zimachitikira
• mimba
• kuyamwa.

Zitha kutsogolera kukula kwa matenda ashuga amtundu wa 2 m'thupi. Chifukwa chake, anthu omwe amakonda matenda ngati amenewo sayenera kugwiritsa ntchito Suvardio kutsitsa cholesterol yamagazi.

Rosucard idalembedwa kuti:

• hypercholesterolemia yoyamba,
• heterozygous cholowa hypercholesterolemia,
• zakudya zowonjezera
• cholowa chapabwinobwino,
• kupitilira kwa atherosulinosis.

Itha kugwiritsidwa ntchito ngati prophylactic motsutsana ndi zovuta zazikulu zamtima:

• kusintha kwamphamvu,
• vuto la mtima
• sitiroko
• matenda a mtima (CHD).

Amapatsidwa kwa anthu odwala:

• Hypersensitivity to rosuvastatin,
• kupita patsogolo kwa matenda a chiwindi
• kulephera kwa chiwindi
• cholowa chamalo
• kulephera kwa aimpso
• myopathy.

Simungatenge Rosucard ndi kuchepa kwa creatine, amayi oyembekezera komanso ana osakwana zaka 18. Amayi oyamwitsa ayeneranso kumwa mankhwalawa, chifukwa palibe chodalirika chokhudza mphamvu ya mankhwalawa kwa ana kudzera mkaka wa m'mawere. Kuzindikira mwangozi - kutenga pakati kumayimira kuchotsedwa kwa mankhwalawa.

Zimakhudza kuthekera koyendetsa magalimoto. Chifukwa chake, munthawi yoyang'anira, ndikofunikira kuyendetsa magalimoto mosamala kwambiri ndikuchita zinthu zomwe zimafunikira kuti anthu aziganiza mwachangu. Mtengo wamba wa mankhwala ndi ma ruble 400.

Gawo lalikulu la Rosart ndi ndende ina ya calcium ya rosuvastatin:

Mankhwalawa amalembedwa kwa anthu azaka zopitilira 18 kuti athandizire matenda otsatirawa:

• Hypercholesterolemia yamitundu yosiyanasiyana,
• kupewa kulephera kwamtima,
• atherosulinosis.

Contraindication kuti agwiritse ntchito ndi:

• kudya mafupa amodzimodzi nthawi yomweyo,
• kuchuluka kwa chidwi chopanga,
• a a Mongol,
• matenda a chiwindi
• kulephera kwa impso
• myopathic
• matenda obadwa nawo a minofu.

Mtengo wapakati wa mankhwalawo ndi ma ruble 411.

Kuchita bwino kwa mapiritsi a Roxer kwatsimikiziridwa ndi ndemanga zambiri zabwino kuchokera kwa odwala ndi madokotala. Ngati ndi kotheka, sinthani mankhwala ndi analogue, muyenera kufunsa dokotala.

Zotheka m'malo mwa Roxer mapiritsi

Analogue ndiotsika mtengo kuchokera ku ma ruble 306.

Chinthu china cha gulu la statin, atorvastatin, chimapangidwa pansi pa mayina Atoris, Torvakard, restator, Amvastan. Mapiritsiwo alibe lactose, chifukwa ndioyenera kwa anthu omwe ali ndi vuto lactase. Atorvastatin ndi yotsika mtengo - kuchokera ku ma ruble 120 pa phukusi lililonse.

Analogue ndiotsika mtengo kuchokera ku ma ruble 217.

Mphamvu yogwira ya Vasilip ndi simvastatin. Vasilip amaloledwa kuphatikizidwa ndi mankhwala ena (cholestyramine, colestipol, okonda mawilo) kuti athandizire kuchepetsa kutsika kwa cholesterol. Nthawi zina, chithandizo chimafuna kuchuluka kwa simvastatin (mpaka 80 mg / tsiku).

Rosistark (mapiritsi) Kutalika: 31 Pamwamba

Analogue ndiotsika mtengo kuchokera ku ma ruble 148.

Rosuvastatin, yomwe imapangidwa ndi Belupo ku Croatia, imatchedwa Rosistark. Mapaketi ang'onoang'ono a mapiritsi 14 amapezeka. Mankhwalawa amagwira ntchito chimodzimodzi monga Roxer, ndipo amagulitsidwa pamtengo wofanana.

Analogue ndiyotsika mtengo kuchokera ku ma ruble 82.

Wothandizira wina wa Roxery, Rosulip, amapangidwa ndi kampani yopanga zamankhwala ku Hungary Egis. Kwa okalamba opitilira 65, mlingo woyambayo umalimbikitsidwa kuti ukhale wotsika 10 mpaka 5 mg patsiku. Wopanga akufufuza kugwiritsa ntchito Rosulip mpaka zaka 18, koma pakadali pano mankhwalawa saloledwa kwa ana.

Analogue ndiotsika mtengo kuchokera ku ma ruble 41.

Mapiritsi a Suvardio, omwe amagulitsidwa ku Slovenia ndi Sandoz, ali ndi zinthu zomwezo. Mankhwalawa amagulitsidwa mu Mlingo wa 10 ndi 20 mg. Mankhwala Suvardio ndi otsika mtengo, phukusi limodzi limadya pafupifupi ma ruble 350.

Rustor (mapiritsi) Kutalika: 20 Pamwamba

Analogue ndiotsika mtengo kuchokera ku ma ruble 41.

Mankhwala osokoneza bongo Rustor akupezeka mu 10 mg. Kuyambira 2014, mankhwalawa adapangidwa ndi kampani ya zamankhwala ku Obolensk m'dera la Moscow. Ngakhale a Russian akupanga, Rustor samawononga ndalama zochepa kuposa mankhwala akunja omwe ali ndi mawonekedwe ofanana.

Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 62.

Mankhwala ena aku Russia, rosuvastatin, Akorta, amapangidwa ndi kampani yayikulu kwambiri yamakampani yotchedwa Pharmstandard. Mankhwalawa adzagulira wogula mtengo - pafupifupi ma ruble 550 a mapiritsi 30. Zina mwa zotsatira zoyipa za Acorta zinaonetsa mphumo, bronchitis, chibayo.

Zizindikiro pakugwiritsa ntchito chida ichi ndi fanizo

Monga tanena kale, chinthu chachikulu chomwe chimagwira mwachangu kuthetsa mavuto azaumoyo ndi rosuvastatin. Kuphatikiza pa kaphatikizidwe komwe kamapangidwa, kapangidwe kake ka mankhwalawo kamaphatikizidwa ndi ena omwe amapezeka:

• magnesium wakuba,
• crospovidone
• lactose.

Mankhwalawa sangagwire ntchito popanda cellcrystalline cellulose.

Komanso, monga Roxer, ma analogu amachita makamaka pachiwindi, popeza chiwalochi ndichopanga cholesterol m'mwazi ndi ziwalo zina zakunja. Mapiritsi kwambiri bwino ndipo mwachangu kuwonjezera kuchuluka kwa chiwindi zolandila. Chifukwa cha izi, kuchuluka kwa cholesterol ndi lipoprotein ena kumachepetsedwa kwambiri masiku.

Mankhwalawa amatchulidwa kuti apatsidwe matenda ambiri. Monga lamulo, mankhwalawa ndimafananidwe ake nthawi zambiri amaperekedwa kwa mitundu yosiyanasiyana ya hypercholesterolemia:

Sizopweteka kutenga ndalama pazinthu zovuta kwambiri.

Nthawi zambiri, analogues amaperekedwa kwa atherosulinosis. Mankhwalawa amagwira ntchito bwino kwa onse odwala omwe ali ndi matenda a mtima. Madokotala amalimbikitsa kugwiritsa ntchito Roxer atalandira zovuta zosavomerezeka ndi matenda oopsa amitsempha yamagazi.

Ndi analogue iti yomwe imawonedwa kuti ndi yofunika kwambiri?

M'malo mwake, Roxer amaonedwa kuti ndi mankhwala abwino, koma siabwino kwa odwala onse omwe amadandaula ndi cholesterol ndi matenda omwe amagwirizana ndi zovulaza izi. Poterepa, akatswiri amalangizidwa kuti asankhe mankhwala apakhomo.

Akatswiri azamankhwala atha kupanga mankhwala ambiri omwe amatha kusintha mankhwalawo. Chimodzi mwazodziwika kwambiri komanso chofunidwa ndi cholesterol ndi fanizo la Roxer monga Atoris ndi Krestor. Mfundo yodziwikiratu mankhwalawa imakhala yofanana. Zotsatira zake nthawi zambiri sizibwera kwa nthawi yayitali; pakatha masiku angapo atadwala, wodwalayo amakhala akusintha. Kusiyana kwakukulu pakati pa mankhwalawa ndi kapangidwe kake.

Zomwe zimagwiritsidwa ntchito ponse pawiri mu njira ya Krestor ndi Roxer ndi rosuvastatin. Titha kunena kuti mankhwalawa ndi ofanana ndendende. Kusiyana pakati pa mankhwalawa ndi wopanga yekha. Ngati Roxeru idapangidwa ndi katswiri wazamankhwala waku Russia, ndiye kuti Krestor ndiye zotsatira za ntchito yopanga akatswiri ochokera kunja, chida chake sichotsika mtengo kwambiri.

Odwala ambiri amati pali kusiyana pakati pa mankhwalawa. Malinga ndi iwo, Krestor amakhudza thupi nthawi zambiri mwachangu, pomwe Roxer wokhala ndi cholesterol amayamba kugwira ntchito kokha atalandira ma phwando angapo. Komabe, kuthamanga kumadaliranso pazinthu zina: mawonekedwe amunthu, thupi, komanso kusasamala kwa matendawa.

Analogue yachiwiri, yomwe ikufunikira kwambiri pamsika wamankhwala otere, ili ndi atorvastatin. Ndi gawo ili lomwe lili chofunikira mu chida. Mtengo wa Atoris sikuti umasiyana ndi mankhwala akale. Ndi cholesterol, tikulimbikitsidwa kuti muigwiritse ntchito ngati prophylactic. Cholesterol imachokanso magawo oyambawo a matendawa. Nthawi zambiri, mankhwala amathandizidwa ngati wodwala wapezeka kuti sakugwirizana ndi Roxer.

Inde, pali mankhwala ena ambiri omwe amathandizanso anthu kuti athetse matenda ena. Pakati pawo, wina amatha kusiyanitsa Rosucard, Rosistark, Tevastor, Emstat, Rosulip ndi ena. Ndiomwe angatchulidwe kuti ndi othandiza kwambiri, ndizosatheka kunena motsimikiza, chifukwa zimatengera munthu ndi thupi lake. Pankhaniyi, wodwala aliyense amafunikira njira yakeyake.

Ngati cholesterol ikulepheretsani kukhala ndi moyo wonse, yambani kumwa mankhwala a Roxer kapena ma analogu ake, koma pokhapokha mutakambirana ndi akatswiri odalirika.

Mndandanda wa mankhwala Roxer

Analogue ndiotsika mtengo kuchokera ku ma ruble 306.

Wopanga: Biocom (Russia)
Kutulutsa Mafomu:

• Mapiritsi 10 mg, 30 ma PC., Mtengo kuchokera ku ma ruble 110
• Mapiritsi 20 mg, 30 ma PC., Mtengo kuchokera ku 186 rubles

Mitengo ya Atorvastatin m'masitolo ogulitsa pa intaneti
Malangizo ogwiritsira ntchito

Atorvastatin ndi piritsi-mawonekedwe kumasulidwa kukonzekera anafuna kuchiza ndi kupewa matenda a mtima. Contraindified pa mimba, mkaka wa m`mawere ndi ana osaposa zaka 18.

Analogue ndiokwera mtengo kwambiri kuchokera ku ma ruble 62.

Wopanga: Dzuwa (Russia)
Kutulutsa Mafomu:

• Mapiritsi 10 mg, 30 ma PC., Mtengo kuchokera 478 ma ruble
• Mapiritsi 20 mg, ma PC 30, Mtengo kuchokera ku ma ruble 790

Mitengo ya acorta m'mafakitale opezeka pa intaneti
Malangizo ogwiritsira ntchito

Akorta ndi mankhwala opangidwa ku Russia omwe amapezeka mwanjira ya mapiritsi ndipo adapangidwira zochizira matenda amtima. Contraindified mu mimba ndi mkaka wa m`mawere. Pali zovuta zina.

Analogue ndiotsika mtengo kuchokera ku ma ruble 41.

Wopanga: Lek dd (Slovenia)
Kutulutsa Mafomu:

• Mapiritsi 10 mg 28 ma PC, mtengo kuchokera 375 ma ruble
• Mapiritsi 20 mg, ma PC 30, Mtengo kuchokera ku ma ruble 790

Mitengo ya Suvardio muma pharmacistine apamtaneti
Malangizo ogwiritsira ntchito

Suvardio ndi mankhwala a ku Slovenia otengera rosuvastatin mu mlingo wa 5 mg. Zizindikiro zazikulu zogwiritsidwa ntchito: hypercholesterolemia yoyambira malinga ndi gulu la Fredrickson, homozygous hypercholesterolemia, hypertriglyceridemia, kupewa kwakukulu kwa mtima wamavuto. Suvardio sanakhazikitsidwe asanafike zaka 18, panthawi yoyembekezera komanso mkaka wa m'mawere. Mndandanda wathunthu wa contraindication ndi zoletsa ukhoza kupezeka mu malangizo ogwiritsa ntchito.

Analogue ndiotsika mtengo kuchokera ku ma ruble 217.

Wopanga: Krka (Slovenia)
Kutulutsa Mafomu:

• Mapiritsi 20 mg, 14 ma PC., Mtengo kuchokera ku ma ruble 199
• Mapiritsi 10 mg, 28 ma PC., Mtengo kuchokera 289 rubles

Mitengo ya Vasilip pamafakitale opezeka pa intaneti
Malangizo ogwiritsira ntchito

Cholowa chopindulitsa kwambiri ku Slovenia ndi mtundu womwewo wamasulidwe ndikugulitsa zinthu. Zizindikiro zazikulu zogwiritsidwa ntchito: chachikulu hypercholesterolemia kapena dyslipidemia, kuchepa kwa kufa kwa mtima ndi kuchepa kwa odwala omwe ali ndi chiwonetsero cha matenda a atherosranceotic mtima kapena matenda a shuga. Pali zotsutsana.

Analogue ndiotsika mtengo kuchokera ku ma ruble 148.

Wopanga: Belupo (Croatia)
Kutulutsa Mafomu:

• Mapiritsi 10 mg 14 ma PC., Mtengo kuchokera ku ma ruble 268
• Mapiritsi 10 mg, 28 ma PC., Mtengo kuchokera 289 rubles

Mitengo ya Rosistark pamafakitale opezeka pa intaneti
Malangizo ogwiritsira ntchito

Rosistark ndi mankhwala a hypolipidemic a group la statins. Kuphatikiza molekyu ya rosuvastatin. Imachepetsa cholesterol ndi tizigawo ting'onoting'ono, amathetsa kusokonekera kwa endothelial. Ili ndi antiproliferative ndi antioxidant katundu. Amalembera hypercholesterolemia, kuchuluka kwa triglycerides m'magazi, kuti athetse kupitirira kwa atherosulinosis ndikuchepetsa ngozi ya mtima. Zinthu zonse zomwe zimakhala ndi rosuvastatin zimagwiritsidwa ntchito nthawi iliyonse masana, mosasamala kanthu za kudya. Mtheradi contraindication ntchito kwambiri matenda a impso ndi chiwindi, myopathy, akazi a mibadwo yobala popanda kulera. Zotsatira zoyipa zoyipa kwambiri, kudzimbidwa, kupweteka mutu, ndi kuwawa kwa minofu.

Analogue ndiyotsika mtengo kuchokera ku ma ruble 82.

Wopanga: Aegis (Hungary)
Kutulutsa Mafomu:

• Tab. tsa / obol. 5 mg, 28 ma PC., Mtengo kuchokera pa ma ruble 334
• Tab. tsa / obol. 10 mg, 28 ma PC., Mtengo kuchokera ku ma ruble 450

Mitengo ya Rosulip pamafakitale opezeka pa intaneti
Malangizo ogwiritsira ntchito

Rosulip ndi rosuvastatin wina wa gulu la statin. Zimapangidwa, monga Rosart, komanso ma rosuvastatins onse omwe alipo, momwe amapangira mapiritsi. Ikatengedwa, imatsitsa kuchuluka kwa cholesterol, otsika komanso otsika kwambiri a lipoproteins (LDL, VLDL), triglycerides, ndikuchulukitsa lipoproteins yapamwamba kwambiri, yomwe imateteza thupi laumunthu ku zovuta zamavuto am'kati ndi ubongo. Amasintha magazi, amateteza mapangidwe a atherosulinotic plaques. Zizindikiro zothandizira, Mlingo ndi makina othandizira, zotsutsana ndi zotsatira zoyipa ndizofanana ndendende ndi Rosartark, popeza mankhwalawa ali ndi rosuvastatin.

Analogue ndiotsika mtengo kuchokera ku ma ruble 41.

Wopanga: Ikufotokozedwa
Kutulutsa Mafomu:

• Tab. tsa / obol. 10 mg, 28 ma PC., Mtengo kuchokera 375 ma ruble
• Tab. tsa / obol. 10 mg, 28 ma PC., Mtengo kuchokera ku ma ruble 450

Mitengo ya rustor muma pharmacistine opezeka pa intaneti
Malangizo ogwiritsira ntchito

Mankhwala osokoneza bongo Rustor akupezeka mu 10 mg. Kuyambira 2014, mankhwalawa adapangidwa ndi kampani ya zamankhwala ku Obolensk m'dera la Moscow. Ngakhale a Russian akupanga, Rustor samawononga ndalama zochepa kuposa mankhwala akunja omwe ali ndi mawonekedwe ofanana.

Analogs popanga ndi chisonyezo chogwiritsidwa ntchito

Mutu	Mtengo ku Russia	Mtengo ku Ukraine
Crestor rosuvastatin	29 rub	60 UAH
Mertenil rosuvastatin	179 rub	77 UAH
Klivas rosuvastatin	--	2 UAH
Sinkhaninso rosuvastatin	--	143 UAH
Rosart Rosuvastatin	47 ma rub	29 UAH
Rosuvastatin Rosator	--	79 UAH
Rosuvastatin Krka rosuvastatin	--	--
Rosuvastatin Sandoz Rosuvastatin	--	76 UAH
Rosuvastatin-Teva Rosuvastatin	--	30 UAH
Rosucard Rosuvastatin	20 rub	54 UAH
Rosulip Rosuvastatin	13 rub	42 UAH
Rosusta Rosuvastatin	--	137 UAH
Romazik rosuvastatin	--	93 UAH
Romestine rosuvastatin	--	89 UAH
Rosucor rosuvastatin	--	--
Fastrong rosuvastatin	--	--
Acorta Rosuvastatin Kalcium	249 rub	480 UAH
Tevastor-Teva	383 rub	--
Rosistark rosuvastatin	13 rub	--
Suvardio rosuvastatin	19 rub	--
Redistatin Rosuvastatin	--	88 UAH
Rustor rosuvastatin	--	--

Mndandanda womwe uli pamwambapa wa analogies ya mankhwala, omwe akuwonetsa cholowa m'malo, ndizabwino kwambiri chifukwa zimakhala ndi zinthu zomwe zimagwirizana ndipo zimagwirana molingana ndi chisonyezo chogwiritsidwa ntchito

Analogs mwa chisonyezo ndi njira yogwiritsira ntchito

Mutu	Mtengo ku Russia	Mtengo ku Ukraine
Vabadin 10 mg simvastatin	--	--
Vabadin 20 mg simvastatin	--	--
Vabadin 40 mg simvastatin	--	--
Vasilip simvastatin	31 rub	32 UAH
Zokor simvastatin	106 rub	4 UAH
Zokor Forte simvastatin	206 rub	15 UAH
Simvatin simvastatin	--	73 UAH
Vabadin	--	30 UAH
Simvastatin	7 rub	35 UAH
Vasostat-Health simvastatin	--	17 UAH
Vasta simvastatin	--	--
Kardak simvastatin	--	77 UAH
Simvakor-Darnitsa simvastatin	--	--
Simvastatin-zentiva simvastatin	229 rub	84 UAH
Simstat simvastatin	--	--
Alleste	--	38 UAH
Zosta	--	--
Lovastatin lovastatin	52 rub	33 UAH
Ufulu wa anthu pravastatin	--	--
Leskol	2586 rub	400 UAH
Leskol Forte	2673 rub	2144 UAH
Leskol XL fluvastatin	--	400 UAH
Amvastan	--	56 UAH
Atorvacor	--	31 UAH
Atoris	34 rub	7 UAH
Vasocline	--	57 UAH
Livostor atorvastatin	--	26 UAH
Liprimar atorvastatin	54 rub	57 UAH
Thorvacard	26 rub	45 UAH
Tulip Atorvastatin	21 rub	119 UAH
Atorvastatin	12 rub	21 UAH
Limistin Atorvastatin	--	82 UAH
Lipodemin Atorvastatin	--	76 UAH
Litorva atorvastatin	--	--
Pleostin atorvastatin	--	--
Tolevas atorvastatin	--	106 UAH
Torvazin Atorvastatin	--	--
Torzax atorvastatin	--	60 UAH
Etset atorvastatin	--	61 UAH
Aztor	--	--
Astin Atorvastatin	89 rub	89 UAH
Atocor	--	43 UAH
Atorvasterol	--	55 UAH
Atotex	--	128 UAH
Novostat	222 rub	--
Atorvastatin-Teva Atorvastatin	15 rub	24 UAH
Atorvastatin Alsi Atorvastatin	--	--
Lipromak-LF atorvastatin	--	--
Vazator atorvastatin	23 rub	--
Atorem atorvastatin	--	61 UAH
Vasoclin-Darnitsa atorvastatin	--	56 UAH
Livazo pitavastatin	173 rub	34 UAH

Kuphatikizika kosiyanasiyana, kungagwirizane mukuwonetsa komanso momwe mungagwiritsire ntchito

Mutu	Mtengo ku Russia	Mtengo ku Ukraine
Lopid Gemfibrozil	--	780 UAH
Lipofen cf fenofibrate	--	129 UAH
Tricor 145 mg fenofibrate	942 rub	--
Trilipix Fenofibrate	--	--
Pms-cholestyramine lalanje lokhazikika waolembera colestyramine	--	674 UAH
Dzungu Mafuta Mbewu	109 rub	14 UAH
Ravisol Periwinkle wocheperako, Hawthorn, Clover dambo, Horse chestnut, White mistletoe, Japan Sofora, Horsetail	--	29 UAH
Mafuta a nsomba a Sisode	--	--
Kuphatikizika kwa Vitrum Cardio kwa zinthu zambiri zogwira ntchito	1137 rub	74 UAH
Kuphatikizika kwa Omacor pazinthu zambiri zogwira ntchito	1320 rub	528 UAH
Mafuta a nsomba yamafuta	25 rub	4 UAH
Kuphatikiza kwa Epadol-Neo pazinthu zambiri zogwira ntchito	--	125 UAH
Ezetrol ezetimibe	1208 rub	1250 UAH
Repata Evolokumab	14 500 rub	UAH 26381
Alirocoumab wamtengo wapatali	--	28415 UAH

Kodi mungapeze bwanji analogue yotsika mtengo ya mankhwala okwera mtengo?

Kuti mupeze chiwonetsero chotsika mtengo cha mankhwala, chofananira kapena chofanana, choyambirira timalimbikitsa kulabadira kapangidwe kake, zomwe ndi zinthu zomwezo zomwe zikugwiritsidwa ntchito ndikuwonetsa. Zomwe zimagwiritsidwanso mosiyanasiyana ndi mankhwalawa zimawonetsa kuti mankhwalawo ndi ofanana ndi mankhwalawo, monga mankhwala ena kapena mitundu ina. Komabe, musaiwale za zovuta zomwe zimagwiritsidwa ntchito ndi mankhwala ofanana, omwe angakhudze chitetezo ndi kugwiranso ntchito. Musaiwale za malangizo a madotolo, kudzipereka nokha kungawononge thanzi lanu, chifukwa chake onani dokotala wanu musanagwiritse ntchito mankhwala.

Malangizo a Roxer

MALANGIZO
pa kugwiritsa ntchito ndalama
ROXER

Kupanga
Mapiritsi okhala ndi filimu 1 tabu.
Pakatikati
Zogwira pophika: rosuvastatin calcium 5.21 mg, 10,2 mg, 15,2 mg, 20,8 mg, 31.25 mg, 41.66 mg.
(ofanana ndi 5, 10, 15, 20 mg wa rosuvastatin, motero)
Othandizira: MCC, lactose, crospovidone, colloidal silicon dioxide, magnesium stearate
Filimu sheath: butyl methacrylate, dimethylaminoethyl methacrylate ndi methyl methacrylate Copolymer (1: 2: 1), macrogol 6000, titanium dioxide, lactose monohydrate

Kufotokozera za mtundu wa kipimo
Mapiritsi, 5 mg: kuzungulira, biconvex, wokutidwa ndi filimu yoyera wokutira, wokhala ndi bevel, wolemba "5" mbali imodzi, woponderezedwa *.
Mapiritsi, 10 mg: kuzungulira, biconvex, wokutidwa ndi filimu yoyera, yokutidwa ndi bevel, wolemba "10", wopindika kumbali imodzi *.
Mapiritsi a 15 mg: ozungulira, biconvex, wokutidwa ndi filimu yoyera, wokhala ndi bevel, wolemba "15", wopindika kumbali imodzi *.
Mapiritsi, 20 mg: ozungulira, biconvex, wokutidwa ndi filimu yoyera yokutira, ndi bevel *.
* Magawo awiri amawoneka pamtanda, pakati ndi loyera.

Zotsatira za pharmacological
Pharmacological kanthu - lipid-kutsitsa, zoletsa HMG-CoA reductase.

Mankhwala
Njira yamachitidwe
Rosuvastatin ndi chosankha, chopewera chopikisana ndi HMG-CoA reductase, enzyme yomwe imatembenuza methylglutaryl coenzyme A mpaka mevalonic acid, kalambulabwalo wa Xc. Cholinga chachikulu cha ntchito ya rosuvastatin ndi chiwindi, komwe kapangidwe ka cholesterol (Chs) ndi LDL catabolism kumachitika.
Rosuvastatin imachulukitsa zolandilira za hepatic LDL pafoni, ndikuwonjezera kukhudzika ndi kutsutsana kwa LDL, komwe kumapangitsa kuti ziletso za VLDL zisinthe, potero kuchepetsa kuchuluka kwa LDL ndi VLDL.

Mankhwala
Rosuvastatin amachepetsa kukhathamiritsa kwa plasma koleji ya LDL cholesterol (Xs-LDL), cholesterol yathunthu, triglycerides (TG), imakulitsa kuchuluka kwa seramu ya HDL cholesterol (Xs-HDL), komanso kumachepetsa kuchuluka kwa apolipoprotein B (ApoV), non-HDL cholesterol, Xs-LD TG-VLDLP ndikuwonjezera kuchuluka kwa apolipoprotein AI (ApoA-I) (onani matebulo 1 ndi 2). Kuchepetsa kuchuluka kwa ma Xs-LDL / Xs-HDL, ma Xs / Xs-HDL okwanira ndi Xs-non-HDL / Xs-HDL, ndi chiyezo XaV / ApoA-I.
The achire zotsatira amakula mkati mwa sabata limodzi atayamba chithandizo, pambuyo 2 milungu chithandizo ukufika 90% ya pazotheka kwambiri. Achire achire kwambiri nthawi zambiri amakwaniritsidwa ndi sabata la 4 ndikuchiritsira ndikugwiritsidwa ntchito pafupipafupi.
Gome 1
Mphamvu yodalira Mlingo wa odwala omwe ali ndi hypercholesterolemia (Friedrichson mtundu IIa ndi IIb) (amatanthauza kusintha kosinthika poyerekeza ndi poyambira)
Mlingo, mg Chiwerengero cha odwala Chs-LDL Chiwerengero Ch Ch-HDL TG Chs-non-HDL Apo B Apo A-I
Placebo 13 -7 -5 3 -3 -7 -3 0
5 mg 17 -45 -33 13 -35 -44 -38 4
10 mg 17 -52 -36 14 -10 -48 -42 4
20 mg 17 -55 -40 8 -23 -51 -46 5
40 mg 18 -63 -46 10 -28 -60 -54 0
Gawo 2
Mlingo wothandizidwa ndi odwala omwe ali ndi mtundu wa IIb ndi IV hypertriglyceridemia malinga ndi Fredrickson)
Dose, mg Chiwerengero cha odwala omwe ali ndi TG Xs-LDL Total Xs Xs-HDL Xs-non-HDL X-non-HDL TG-VLDL
Placebo 26 1 5 1 -3 2 2 6
5 mg 25 -21 -28 -24 3 -29 -25 -24
10 mg 23 -37 -45 -40 8 -49 -48 -39
20 mg 27 -37 -31 -34 22 -43 -49 -40
40 mg 25 -43 -43 -40 17 -51 -56 -48
Mphamvu zamankhwala. Rosuvastatin imagwira ntchito mwa odwala akuluakulu omwe ali ndi hypercholesterolemia yokhala kapena wopanda hypertriglyceridemia, mosaganizira mtundu, jenda kapena msinkhu, incl. Odwala matenda a shuga ndi matenda am'magazi.
Mu 80% ya odwala omwe ali ndi mtundu wa IIa ndi IIb hypercholesterolemia malinga ndi Fredrickson (pafupifupi koyamba seramu ya LDL-C ndi pafupifupi 4.8 mmol / L) mukamamwa mankhwalawa pa 10 mg, kuchuluka kwa LDL-C kumafika ochepera 3 mmol / L.
Odwala omwe ali ndi heterozygous Famer hypercholesterolemia akulandira mlingo wa 20-80 mg wa rosuvastatin, chidwi cha lipid mbiri chidawonetsedwa (kafukufuku wokhudza odwala 435). Pambuyo posankha mlingo wa tsiku ndi tsiku wa 40 mg (masabata 12 a mankhwala), kuchepa kwa seramu ndende ya LDL-C ndi 53% kumadziwika. Mu 33% ya odwala, kuchuluka kwa ma seramu a LDL-C ndi ochepera 3 mmol / L.
Odwala omwe ali ndi homozygous Famer hypercholesterolemia akutenga rosuvastatin pa 20 ndi 40 mg, kutsika kwapakati pa seramu ndende ya LDL-C inali 22%.
Odwala omwe ali ndi hypertriglyceridemia ndi seramu yoyamba ya TG ndende ya 273 mpaka 817 mg / dl, kulandira rosuvastatin pa mlingo wa 5 mpaka 40 mg kamodzi patsiku kwa masabata a 6, kuchuluka kwa TG m'madzi a m'magazi kunachepetsedwa kwambiri (onani tebulo 2).
Mphamvu yowonjezera imawonedwa limodzi ndi fenofibrate molingana ndi zomwe zimapangidwa ndi triglycerides komanso nicotinic acid mu lipid kutsitsa Mlingo pokhudzana ndi kuchuluka kwa HDL-C (onaninso "Maupangiri Apadera").
Pakufufuza kwa METEOR mwa odwala 984 azaka zapakati pa 45-70 okhala ndi chiopsezo chochepa chotenga matenda am'mitsempha yamagazi (chiwopsezo cha zaka 10 pamlingo wa Framingham osakwana 10%), ndi kuchuluka kwa serum kwa LDL-C wa 4 mmol / l (154,5 mg / dl) ndi Subclinical atherosulinosis (yomwe imayesedwa ndi makulidwe a carotid intima-media tata (TCIM)) idaphunzira zotsatira za rosuvastatin pa TCIM. Odwala adalandira rosuvastatin pa mlingo wa 40 mg / tsiku kapena placebo kwa zaka 2. chithandizo cha Rosuvastatin chachedwa kwambiri zaluso Rhee poyerekeza placebo ndi kusiyana kwa -0,0145 mamilimita / chaka (95% CI -0,0196 kuti -0,0093, p mudziwe onse anapereka zolinga pazankhani ndipo si chifukwa chololera mankhwala kapena m'malo kopita