Malangizo ogwiritsira ntchito mankhwala osokoneza bongo, analogi, ndemanga

Nambala ya Setifiketi Yamalembetsa: P N011270 / 01-171016
Dzina la malonda a mankhwalawa: Amoxicillin Sandoz®.
Dongosolo losavomerezeka: Amoxicillin.
Fomu ya Mlingo: Mapiritsi okhala ndi filimu.

Kufotokozera
Mapiritsi a Oblong (mulingo wa 0,5 g) kapena oil (mulingo wa 1.0 g) biconvex mapiritsi, okhala ndi utoto wokutidwa kuyambira kuyera mpaka pang'ono chikaso, utoto mbali zonse ziwiri.

Kupanga
Piritsi limodzi la 0,5 g ndi 1.0 g lili ndi:
Pakatikati
Zogwira pophika: amoxicillin (mu mawonekedwe a amoxicillin trihydrate) 500.0 mg (574.0 mg) ndi 1000.0 mg (1148.0 mg), motero.
Omwe amathandizira: magnesium stearate 5.0 mg / 10,0 mg, povidone 12,5 mg / 25.0 mg, sodium carboxymethyl wowuma (mtundu A) 20,0 mg / 40.0 mg, microcrystalline cellulose 60.5 mg / 121 mg
Filamu sheath: titanium dioxide 0,340 mg / 0.68 mg, talc 0.535 mg / 1.07 mg, hypromellose 2.125 mg / 4.25 mg.

Gulu la Pharmacotherapeutic
Antibiotic gulu la semisynthetic penicillin.

Code ya ATX: J01CA04

Pharmacodynamic kanthu

Mankhwala
Amoxicillin ndi penicillin wopanga wocheperako wokhala ndi bactericidal. Kupanga kwa bactericidal zochita za amoxicillin kumalumikizidwa ndikuwonongeka kwa cell membrane wa bakiteriya pakufalikira. Amoxicillin amalepheretsa ma enzymes a cell cell nembanemba (peptidoglycans), zomwe zimapangitsa kuti aziyamwa komanso kufa.
Yogwira:
Bakiteriya wabwino wa aerobic
Bacillus anthracis
Corynebacterium spp. (kupatula Corynebacterium jeikeium)
Enterococcus faecalis
Listeria monocytogene
Streptococcus spp. (kuphatikiza Streptococcus pneumoniae)
Staphylococcus spp. (kupatula penicillinase wotulutsa tinthu tosiyanasiyana).
Bakiteriya wa a grob-aerobic
Borrelia sp.
Escherichia coli
Haemophilus spp.
Helicobacter pylori
Leptospira spp.
Neisseria spp.
Proteus mirabilis
Salmonella spp.
Shigella spp.
Treponema spp.
Campylobacter
Zina
Chlamydia spp.
Mabakiteriya a Anaerobic
Bacteroides melaninogenicus
Clostridium spp.
Fusobacterium spp.
Peptostreptococcus spp.
Zosagwira pa:
Bakiteriya wabwino wa aerobic
Staphylococcus (β-lactamase yopangira)
Bakiteriya wa a grob-aerobic
Spinetobacter spp.
Citrobacter spp.
Enterobacter spp.
Klebsiella spp.
Moraxella catarrhalis
Proteus spp.
Providencia spp.
Pseudomonas spp.
Serratia spp.
Mabakiteriya a Anaerobic
Bacteroides spp.
Zina
Mycoplasma spp.
Ratchtsia spp.
Pharmacokinetics
Mtheradi bioavailability wa amoxicillin amadalira mlingo ndipo kuchokera 75 mpaka 90%. Kukhalapo kwa chakudya sikukhudza kuyamwa kwa mankhwalawa. Zotsatira zamkamwa makonzedwe a amoxicillin limodzi mlingo wa 500 mg, kuchuluka kwa mankhwalawa mu plasma ndi 6-11 mg / l. Pambuyo pakukonzekera pakamwa, kuchuluka kwambiri kwa plasma kumachitika pambuyo pa maola 1-2.
Pakati pa 15% ndi 25% ya amoxicillin imamangiriza mapuloteni a plasma. Mankhwalawa amalowerera mosavuta m'matumbo a m'mapapo, kupuma kwa bronchial, madzi apakati amkati, bile ndi mkodzo. Pakusatupa kwam'mimba, amoxicillin amalowa m'madzi amadzimadzi ochepa. Ndi kutupa kwa meninges, kuchuluka kwa mankhwalawa m'madzi am'magazi kungakhale 20% ya kukhazikika kwake m'madzi a m'magazi. Amoxicillin amawoloka chikhodzodzo ndipo amapezeka ochepa mkaka wa m'mawere.
Mpaka 25% ya mlingo womwe umayendetsedwa umapangidwa kuti apange penicilloic acid.
Pafupifupi 60-80% ya amoxicillin amachotsedwa osasinthika ndi impso mkati mwa maola 6-8 mutatha kumwa mankhwalawa. Pang'ono pake mankhwalawa amachotsedwa mu ndulu. Hafu ya moyo ndi maola 1-1,5. Odwala omwe ali ndi vuto loti aimpso amalephera, theka la moyo limasiyana kuchokera maola 5 mpaka 20. Mankhwala amachotsedwa ndi hemodialysis.

Amoxicillin amasonyezedwa matenda opatsirana komanso otupa oyambitsidwa ndi mabakiteriya osagwiritsa ntchito mankhwala:
• Matenda opatsirana a kumtunda komanso kwam'munsi kupuma kwamatumbo ndi ziwalo za ENT (tonsillitis, atitis otitis media, pharyngitis, bronchitis, chibayo, zotupa zam'mapapo,
• Matenda opatsirana a genitourinary system (urethritis, pyelonephritis, pyelitis, bacterialitisatitis, cyidymitis, cystitis, adnexitis, mimba ya septic, endometritis, etc.),
• matenda am'mimba: bacterial enteritis. Kuphatikiza mankhwala kungafunike pamatenda oyambitsidwa ndi anaerobic tizilombo,
• Matenda opatsirana komanso otupa a biliary thirakiti (cholangitis, cholecystitis),
• kuthetsa kwa Helicobacter pylori (kuphatikiza ndi proton pump inhibitors, clarithromycin kapena metronidazole),
• matenda a pakhungu ndi minofu yofewa,
• leptospirosis, listeriosis, matenda a Lyme (borreliosis),
• endocarditis (kuphatikizapo kupewa endocarditis munthawi ya mano).

Contraindication

• Hypersensitivity kuti amoxicillin, penicillin ndi zina za mankhwala,
• mwachangu kwambiri hypersensitivity reaction (mwachitsanzo, anaphylaxis) ku mankhwala ena a beta-lactam monga cephalosporins, carbapenems, monobactams (zotheka pakuyankha),
• msinkhu wa ana mpaka zaka zitatu (fomu iyi).

Ndi chisamaliro

• aimpso ntchito,
• Kukhazikika kwa kukokana,
• kupukusa kwambiri m'mimba, limodzi ndi kusanza kosalekeza komanso kutsegula m'mimba,
• matupi awo sagwirizana,
• mphumu,
• hay fever,
• matenda opatsirana ndi ma virus,
• pachimake lymphoblastic leukemia,
• matenda a mononucleosis (chifukwa cha chiwopsezo cha chotupa pakhungu),
• mwa ana opitirira zaka zitatu.

Gwiritsani ntchito pa nthawi yoyembekezera komanso nthawi yoyamwitsa

Kafukufuku wazinyama awonetsa kuti amoxicillin alibe embryotoxic, teratogenic ndi mutagenic kwambiri pa mwana wosabadwayo. Komabe, kafukufuku wokwanira komanso wowongolera moyenera kugwiritsa ntchito amoxicillin mwa amayi apakati sanachitike, chifukwa chake, kugwiritsa ntchito amoxicillin pa nthawi yomwe ali ndi pakati kumatheka pokhapokha ngati phindu lomwe limayembekezera kwa mayi likupereka chiwopsezo kwa mwana wosabadwayo.
Mankhwala ochepa amawachotsa mkaka wa m'mawere, kotero pochiza ndi amoxicillin mukamayamwa, ndikofunikira kuthana ndi vuto la kuyimitsa kuyamwitsa, chifukwa kutsekula m'mimba ndi / kapena candidiasis ya mucosa yamlomo imatha kukulira, komanso chidwi ndi mankhwala a beta-lactam mwa khanda yemwe ali yoyamwitsa.

Mlingo ndi makonzedwe

Mkati.
Chithandizo cha matenda:
Monga lamulo, chithandizo chamankhwala chikulimbikitsidwa kupitiliza kwa masiku awiri atatha kutha kwa zizindikiro za matendawa. Pankhani ya matenda obwera chifukwa cha β-hemolytic streptococcus, kuthetseratu kwathunthu kwa pathogen kumafunikira chithandizo kwa masiku osachepera 10.
Paresteral chithandizo akuwonetsedwa chifukwa cha kuthekera kwa makonzedwe apakamwa komanso kuchiza matenda oopsa.
Mlingo wa akulu (kuphatikizapo odwala okalamba):
Mulingo wamba:
Mulingo wamba umachokera pa 750 mg mpaka 3 ga amoxicillin patsiku kangapo. Nthawi zina, tikulimbikitsidwa kuti muchepetse mlingo wa 1500 mg wa tsiku patsiku zingapo.
Njira yochepa yothandizira:
Osavuta kwamikodzo thirakiti matenda: kumwa 2 ga mankhwalawa kawiri pa jekeseni iliyonse ndi gawo pakati pakati Mlingo wa maola 10-12.
Mlingo wa ana (mpaka zaka 12):
Mlingo wa tsiku ndi tsiku wa ana ndi 25-50 mg / kg / tsiku pamadontho angapo (pazipita 60 mg / kg / tsiku), kutengera ndi kuwonetsa kwa matendawa.
Ana osaposa 40 makilogalamu ayenera kulandira munthu wamkulu.
Mlingo wa kulephera kwa impso:
Odwala omwe ali ndi vuto lalikulu la impso, mlingo uyenera kuchepetsedwa. Ndi chilolezo chokhala ndi impso zosakwana 30 ml / min, kuwonjezeka kwakanthawi pakati pa Mlingo kapena kuchepa kwa Mlingo wotsatira tikulimbikitsidwa. Mu kulephera kwa aimpso, maphunziro ochepa a 3 g amatsutsana.

Akuluakulu (kuphatikiza odwala okalamba):
Creatinine chilolezo ml / mphindi Mlingo pakati Mlingo
> Kusintha kwa 30 kosafunika
10-30 500 mg 12 h

Ndi hemodialysis: 500 mg ayenera kuperekedwa pambuyo pa njirayi.

Aimpso kuwonongeka kwa ana masekeli zosakwana 40 makilogalamu
Creatinine chilolezo ml / mphindi Mlingo pakati Mlingo
> Kusintha kwa 30 kosafunika
10-30 15 mg / kg 12 h

Kuteteza kwa Endocarditis

Pofuna kupewa endocarditis odwala osagwiritsa ntchito opareshoni, 3 g ya amoxicillin ayenera kutumikiridwa 1 ora asanachitidwe opaleshoni, ndipo ngati n`koyenera, 3 ga pambuyo 6 maola.
Ana akulimbikitsidwa kuti apereke mankhwala amoxillin pa 50 mg / kg.
Kuti mumve zambiri komanso mafotokozedwe amitundu yamagulu omwe ali pachiwopsezo cha endocarditis, werengani malangizo omwe akuperekedwa.

Zotsatira zoyipa

Malinga ndi World Health Organisation (WHO), zotsatira zosafunikira zimagawidwa malinga ndi kuchuluka kwa chitukuko motere: pafupipafupi (≥1 / 10), nthawi zambiri (kuyambira ≥1 / 100 pakusokonekera kwa mtima ndi mitsempha yamagazi
Nthawi zambiri: tachycardia, phlebitis,
osachepera: kutsitsa magazi,
zosowa kwambiri: kutalika kwa nthawi ya QT.
Kusokonezeka kwa magazi ndi dongosolo la lymphatic
chosowa kwambiri: leukopenia yosinthika (kuphatikiza kwambiri neutropenia ndi agranulocytosis), kusintha kosinthika kwa thrombocytopenia, hemolytic anemia, kuchuluka kwa nthawi ya magazi, kuchuluka kwa prothrombin nthawi,
pafupipafupi osadziwika: eosinophilia.
Kusokonezeka Kwa Magazi
kawirikawiri: zotengera zofanana ndi matenda a seramu,
chosowa kwambiri: thupi lawo siligwirizana, kuphatikizapo angioedema, anaphylactic mantha, matenda a seramu ndi ziwengo za vasculitis,
pafupipafupi osadziwika: Jarisch-Herksheimer reaction (onani "Maupangiri Apadera").
Kusokonezeka kwamanjenje
Nthawi zambiri: kugona, kupweteka mutu,
kawirikawiri: mantha, kukwiya, nkhawa, ataxia, kusintha kwa machitidwe, zotumphukira za m'mitsempha, kuda nkhawa, kugona tulo, kukhumudwa, kupsinjika, kugwedezeka, chisokonezo,
osowa kwambiri: hyperkinesia, chizungulire, kupsinjika, kuchepa kwa thupi, masoka operewera, kununkhiza ndi chidwi chamanyazi, kuyerekezera zinthu.
Kuphwanya impso ndi kwamikodzo thirakiti
kawirikawiri: kuchuluka kwa serum creatinine ndende,
osowa kwambiri: interstitial nephritis, crystalluria.
Matenda Am'mimba
Nthawi zambiri: nseru, kutsegula m'mimba,
pafupipafupi: kusanza,
kawirikawiri: dyspepsia, kupweteka m'dera la epigastric,
kawirikawiri kwambiri: anti-bacterial colitis * (kuphatikizapo pseudomembranous ndi hemorrhagic colitis), kutsegula m'mimba ndi kuphatikizika kwa magazi, mawonekedwe a lilime lakuda (lilime la "tsitsi"),
pafupipafupi osadziwika: kusintha kwa kukoma, stomatitis, glossitis.
Kuphwanya chiwindi ndi njira ziwiri
Nthawi zambiri: kuchuluka kwa serum bilirubin,
kawirikawiri: hepatitis, cholestatic jaundice, kuchuluka kwa "chiwindi" transaminases (alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, γ-glutamyl transferase, pachimake chiwindi.
Kusokonezeka kwa minofu ndi mafupa
kawirikawiri: arthralgia, myalgia, matenda a tendon, kuphatikizapo tendonitis,
kawirikawiri kwambiri: kupindika kwa tendon (kuthekera kwa pakati komanso maola 48 atatha chithandizo), kufooka kwa minofu, rhabdomyolysis.
Kusokonezeka kwa khungu ndi minofu yolowerera
Nthawi zambiri: zidzolo
kawirikawiri: urticaria, kuyabwa,
kawirikawiri kwambiri: photosensitivity, kutupa kwa khungu ndi mucous nembanemba, poyizoni epermosis necrolysis * (matenda a Lyell), Stevens-Johnson syndrome *, erythema multiforme *, oxous exfoliative dermatitis *, pachimake kwambiri pantulosis *.
Kusokonezeka kwa dongosolo la endocrine
osowa: anorexia,
chosowa kwambiri: hypoglycemia, makamaka kwa odwala matenda a shuga.
Matenda opatsirana
kawirikawiri: bronchospasm, kupuma movutikira,
osowa kwambiri: matumbo a chifuwa.
Matenda opatsirana komanso parasitic
osati kawirikawiri: kupambana kwakukulu (makamaka kwa odwala omwe ali ndi matenda osachiritsika kapena kutsika kwamthupi),
osowa kwambiri: candidiasis a pakhungu ndi mucous nembanemba.
Zovuta ndi zovuta zina pamalo opangira jakisoni:
kawirikawiri: kufooka wamba,
chosowa kwambiri: malungo.
* - Zotsatira zoyipa zomwe zalembedwa m'nthawi ya malonda.

Kuchita ndi mankhwala ena

Ndikotheka kuwonjezera mayamwidwe a digoxin pa nthawi ya mankhwala ndi Amoxicillin Sandoz®. Kusintha kwa mlingo wa Digoxin kungafunike.
Kugwiritsa ntchito pamodzi kwa amoxicillin ndi phenenecid, komwe kumachepetsa kuchuluka kwa impso ndi impso ndikuchulukitsa kuchuluka kwa amoxicillin mu bile ndi magazi, osavomerezeka.
Kugwiritsa ntchito pamodzi kwa amoxicillin ndi mankhwala ena a bacteriostatic (macrolides, tetracyclines, sulfanilamides, chloramphenicol) kuyenera kupewedwa chifukwa cha kuthekera kwa kukhazikika kwa zotsatira zoyipa. Ndi munthawi yomweyo kugwiritsa ntchito aminoglycosides ndi amoxicillin, mgwirizano wothandizirana umatheka.
Kugwiritsira ntchito nthawi yomweyo ya amoxicillin ndi disulfiram sikulimbikitsidwa.
Ndi munthawi yomweyo kugwiritsa ntchito methotrexate ndi amoxicillin, kuwonjezereka kwa poizoni wa m'mbuyomu ndizotheka, mwina chifukwa cha mpikisano wa tubular renal secretion wa methotrexate ndi amoxicillin.
Maantacid, glucosamine, mankhwala othandizira, aminoglycosides amachepetsa ndikuchepetsa mayamwidwe, ascorbic acid imawonjezera kuyamwa kwa amoxicillin.
Amoxicillin imawonjezera kugwira ntchito kwa anticoagulants osalunjika (kupondereza microflora yamatumbo, kumachepetsa kaphatikizidwe ka vitamini K ndi index ya prothrombin).
Kugwiritsa ntchito mosalekeza ndi njira yolerera yokhala ndi estrogen kungapangitse kuchepa kwa mphamvu yawo ndikuwonjezera pachiwopsezo cha kutuluka kwa magazi.
Mabukuwa amafotokoza milandu ya kuchuluka kwa anthu wamba padziko lonse lapansi (INR) ndi kuphatikiza kwa acenocoumarol kapena warfarin ndi amoxicillin. Ngati ndi kotheka, kugwiritsa ntchito mankhwalawa munthawi yomweyo anticoagulants, prothrombin nthawi kapena INR iyenera kuyang'aniridwa mosamala pakumwa kapena ngati mankhwala atachotsedwa, kusintha kwa mankhwalawa kosagwirizana ndi anticoagulants kungafunike.
Ma diuretics, allopurinol, oxyphenbutazone, mankhwala osokoneza bongo omwe amaletsa kutupa komanso mankhwala ena omwe amalepheretsa katulutsidwe ka tubular kumakulitsa kuchuluka kwa amoxicillin m'magazi.
Allopurinol imawonjezera chiopsezo chotenga khungu. Kugwiritsa ntchito pamodzi kwa amoxicillin ndi allopurinol sikulimbikitsidwa.

Malangizo apadera

Musanayambe kugwiritsa ntchito amoxicillin, muyenera kusanja tsatanetsatane wa zochita za hypersensitivity ku penicillin, cephalosporins, kapena mankhwala ena a beta-lactam. Zowopsa, nthawi zina zakupha, hypersensitivity reaction (anaphylactic reaction) ku penicillins amafotokozedwa. Chiwopsezo chotere chimakhala chokwanira kwambiri kwa odwala omwe ali ndi mbiri ya hypersensitivity reaction ku penicillins. Ngati thupi lanu siligwirizana, ndikofunikira kusiya mankhwalawa ndikuyamba njira zina zoyenera.
Musanalembe mankhwala Amoxicillin Sandoz ®, muyenera kuonetsetsa kuti tizilombo tosiyanasiyana tomwe timayambitsa matenda opatsirana timayang'anitsitsa mankhwala.Pankhani ya mononucleosis wopatsirana yemwe akuganiziridwa, mankhwalawa sayenera kugwiritsidwa ntchito, chifukwa mwa odwala omwe ali ndi matendawa, amoxicillin imatha kuyambitsa kuwoneka ngati zotupa pakhungu.
Ndikotheka kukhala ndi superinitness chifukwa cha kukula kwa microflora sazindikira izi, zomwe zimafunikira kusintha kofananirana ndi mankhwala opha maantibayotiki.
Ndi njira ya chithandizo, ndikofunikira kuwunika momwe ntchito ya magazi, chiwindi ndi impso.
Mwa matenda opatsirana otupa komanso otupa m'matumbo am'mimba, omwe amaphatikizidwa ndi kutsekula kwa m'mimba kwa nthawi yayitali kapena osokoneza bongo, sikuti amalimbikitsidwa kumwa Amoxicillin Sandoz ® mkatikati chifukwa amatha kuyamwa.
Pochiza matenda am'mimba opatsirana pogwiritsa ntchito mankhwalawa, mankhwala othandizira omwe amachepetsa matumbo amayenera kupewedwa, ndipo kaolin kapena mankhwala okhala ndi antidiarrheal angagwiritsidwe ntchito. Kwa matenda otsegula m'mimba, funsani dokotala.
Ndi kukula kwa kutsekula kwambiri kwa m'mimba, kukulitsa kwa pseudomembranous colitis (chifukwa cha Clostridium Hardile) sikuyenera kuyikidwa pambali. Pankhaniyi, Amoxicillin Sandoz® iyenera kusiyidwa ndikuyenera kulandira chithandizo chamankhwala.
Kuchiza kumapitirirabe kwa maola ena 48-72 atatha kutha kwa zizindikiro za matenda.
Pogwiritsa ntchito nthawi imodzimodziyo mankhwala okhala ndi pakamwa okhala ndi estrogen komanso amoxicillin, njira zina kapena zowonjezera zakulera ziyenera kugwiritsidwa ntchito ngati kuli kotheka.
Amoxicillin Sandoz ® sayenera kuvomerezeka pochizira matenda opatsirana oyambitsidwa ndi ma virus chifukwa chosakwanira ma virus.
Pa mankhwala, Mowa samalimbikitsa.
Mwina chitukuko cha kukomoka m'magulu otsatirawa a odwala: ndi vuto laimpso, kulandira mlingo waukulu wa mankhwalawa, ndikulakalaka kukomoka (mbiri: khunyu, khunyu, matenda amisala).
Maonekedwe kumayambiriro kwa chithandizo cha mankhwala okhala ndi amoxicillin monga erythema yodziwika bwino, yothandizidwa ndi malungo ndi ma pustule, ikhoza kukhala chizindikiro cha pustulosis yamphamvu kwambiri. Kuchita kotereku kumafuna kusiya kwa mankhwala a amoxicillin ndipo ndikolepheretsa kugwiritsa ntchito mankhwalawa mtsogolo.
Popereka mankhwala kwa odwala omwe ali ndi vuto la impso, kusintha kwa mankhwalawa ndikofunikira malinga ndi kuchuluka kwa kuphwanya (onani gawo "Mlingo ndi Administration").
Mankhwalawa matenda a Lyme ndi amoxicillin, kukula kwa Yarish-Herxheimer anachita, zomwe zimachitika chifukwa cha bactericidal zotsatira za mankhwala pa causative wothandizila matendawa - spirochete Borrelia burgdorferi. Ndikofunikira kudziwitsa odwala kuti vutoli ndiwofala kwambiri chifukwa cha mankhwala opha maantibayotiki ndipo, monga lamulo, limadutsa lokha.
Nthawi zina, kuchuluka kwa prothrombin nthawi kumanenedwa kwa odwala omwe amalandila amoxicillin. Odwala omwe akuwonetsedwa nthawi yomweyo yophatikiza anticoagulants ayenera kuwonedwa ndi katswiri. Kusintha kwa mlingo wa anticoagulants osavomerezeka kungakhale kofunikira.
Mukamamwa Amoxicillin Sandoz®, tikulimbikitsidwa kuti mumagwiritsa ntchito madzi ambiri kuti muchepetse mapangidwe a makhwala a amoxicillin mkodzo.
A kuchuluka kwa amoxicillin mu magazi seramu ndi mkodzo kungasokoneze mayeso a zasayansi. Mwachitsanzo, kugwiritsa ntchito Amoxicillin Sandoz® kungayambitse urinalosis wabwinobwino wopanga shuga. Kuti mudziwe izi, ndikofunikira kugwiritsa ntchito njira ya glucose oxidase.
Pogwiritsa ntchito amoxicillin, zolakwika zosankha kuchuluka kwa estriol (estrogen) mwa amayi apakati zimatha kupezeka.

Kukopa pa kuyendetsa magalimoto, machitidwe

Kafukufuku wokhudzana ndi amoxicillin pakutha kuyendetsa magalimoto, njira sizinachitike. Odwala ayenera kuchenjezedwa za kuthekera kwa chizungulire ndi kugwidwa. Pakachitika zovuta zomwe tafotokozazi tiyenera kupewa kuchita izi.

Kutulutsa Fomu
Mapiritsi okhala ndi mafilimu, 0,5 g ndi 1 g.
Mlingo 0,5 g
Katundu woyamba
Mapiritsi 10 kapena 12 pa blister ya PVC / PVDC / aluminium.
Kukhazikitsa kwachiwiri
Kulongedza payekha
Chithuza chimodzi (chokhala ndi mapiritsi 12) pabokosi lamakadi okhala ndi malangizo ogwiritsa ntchito.
Katemera wa zipatala
Matuza 100 (okhala ndi mapiritsi 10) okhala ndi malangizo ofanana kuti agwiritse ntchito pabokosi lamakhadi.
Mlingo 1.0 g
Katundu woyamba
Mapiritsi 6 kapena 10 mu chithuza cha PVC / PVDC / aluminium.
Kukhazikitsa kwachiwiri
Kulongedza payekha
2 matuza (okhala ndi mapiritsi 6) pabokosi lamakadi okhala ndi malangizo ogwiritsira ntchito.
Katemera wa zipatala
Matuza 100 (okhala ndi mapiritsi 10) okhala ndi malangizo ofanana kuti agwiritse ntchito pabokosi lamakhadi.

Malo osungira
Sungani ku kutentha kosaposa 25 ° C.
Pewani kufikira ana.

Njira zopewera kusamala pochotsa chinthu chosagwiritsidwa ntchito
Palibe chifukwa chofunikira kusamala mwapadera mukataya mankhwala osagwiritsidwa ntchito.

Tsiku lotha ntchito
Zaka 4
Osagwiritsa ntchito tsiku lotha ntchito likusonyezedwa pa phukusi.

Migwirizano ya Tchuthi
Ndi mankhwala.

Wopanga
Sandoz GmbH, Biohemistrasse 10, A-6250 Kundl, Austria.

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Foni: (495) 660-75-09,
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