Matekinoloje opangira chithandizo cha matenda a shuga

Type 2 matenda a shuga a mellitus (T2DM) ndi matenda achilengedwe omwe maselo amthupi amalephera kumva za insulin ndikusiya kuyamwa glucose, chifukwa chomwe chimayamba kukhazikika m'magazi.

Pofuna kupewa kuchuluka kwa shuga m'magazi, madokotala amalimbikitsa kuti odwala matenda ashuga azitsatira zakudya zochepa komanso masewera olimbitsa thupi.

Komabe, njirazi sizipereka zotsatira zabwino nthawi zonse, ndipo matendawa amayamba kupita patsogolo, omwe amakakamiza munthu kusintha machitidwe owonjezereka - kupita ku maphunziro achipatala. Koma pali china chatsopano pakuchiza matenda a shuga 2, omwe tikambirane tsopano.

Mawu ochepa onena za matendawa

Mosiyana ndi mtundu woyamba wa matenda ashuga, T2DM ndiyotheka kuchira, makamaka ngati mungayambitse m'nthawi yake. Ndi matendawa, ntchito ya kapamba imasungidwa, ndiye kuti, palibe kuchepa kwa insulin mthupi, monga momwe zimakhalira poyamba. Chifukwa chake, chithandizo chamankhwala sichofunikira pano.

Komabe, chifukwa cha kupangidwa kwa T2DM, kuchuluka kwa shuga mumwazi, kapamba "amakhulupirira" kuti sagwira ntchito mokwanira komanso kumathandizira kupanga insulin. Zotsatira zake, chiwalochi chimakakamizika kupsinjika kwambiri, zomwe zimapangitsa kuwonongeka pang'onopang'ono kwa maselo ake komanso kusintha kwa T2DM kupita ku T1DM.

Chifukwa chake, madokotala amalimbikitsa kuti odwala awo aziyang'anira kuchuluka kwa shuga m'magazi awo ndipo, akachuluka, nthawi yomweyo amachitapo kanthu kuti achepetse malire ake. Ndi T2DM, ndizokwanira kumangotsatira kadyedwe ndi masewera olimbitsa thupi. Ngati izi sizithandiza, mutha kuyang'ana ku thandizo la mankhwala ochepetsa shuga.

Koma chithandizo chonsechi cha shuga chimatha.

Ndipo poganizira kuti chiwerengero cha anthu omwe akudwala matendawa chikuwonjezeka chaka chilichonse, madokotala akuwonjezeranso njira yatsopano ya 2 yothandizira odwala matenda ashuga omwe amaperekedwa ndi asayansi komanso makampani osiyanasiyana opanga mankhwala. Kodi amalola kugonjetsa matendawa, kapena amalepheretsa kupitilira kwake? Izi ndi zina zambiri tidzazikambirana tsopano.

Njira zatsopano zamankhwala zopangira T2DM zimagwiritsa ntchito njira zamakono zamankhwala, zomwe zimaphatikizapo zomwe zimatchedwa glitazones. Amagawika m'magulu awiri - pioglitazones ndi rosiglitazones.

Zinthu zothandizazi zimathandizira kukondoweza kwa ma receptors omwe amapezeka mu nuclei ya adipose ndi minofu minofu.

Pamene maphikidwe awa adakonzedwa, pamakhala kusintha kwa zolembedwa zamtundu zomwe zimayambitsa kupezeka kwa glucose ndi lipid metabolism, chifukwa chomwe maselo amthupi amayamba kulumikizana ndi insulin, kuyamwa glucose ndikuletsa kuti asakhazikike m'magazi.

Limagwirira ntchito ya glitazones

Mankhwala otsatirawa ali m'gulu la pioglitazones:

Kudya kwa mankhwalawa kumachitika kamodzi kokha patsiku, mosasamala nthawi yakudya. Kumayambiriro kwenikweni kwa chithandizo, mlingo wawo ndi 15-30 mg.

Zikachitika kuti pioglitazone sichimapereka zotsatira zabwino motere, mlingo wake umachulukitsidwa kufika pa 45 mg.

Ngati mankhwalawa atengedwa limodzi ndi mankhwala ena othandizira T2DM, ndiye kuti mlingo wake woyenera sayenera kupitirira 30 mg patsiku.

Zokhudza rosiglitazones, mankhwala otsatirawa ndi a gulu lawo:

Mankhwalawa aposachedwa amatengedwa pakamwa kangapo patsiku, komanso mosasamala nthawi yakudya.

Pa magawo oyambirira a mankhwalawa, mlingo wa tsiku ndi tsiku wa rosinlitazone ndi 4 mg (2 mg imodzi). Ngati mavutowo sanawonedwe, amatha kuwonjezeka mpaka 8 mg.

Popanga mankhwala ophatikiza, mankhwalawa amatengedwa pamlingo wochepa - osapitirira 4 mg pa tsiku.

Mankhwala "Actos" amatanthauza gulu latsopano la mankhwala

Posachedwa, mankhwalawa amagwiritsidwa ntchito kwambiri ngati mankhwala pochiza matenda amtundu wa 2. Ma rosiglitizans onse ndi pioglitazones ali ndi zabwino zambiri. Kulandila kwawo kumapereka:

• utachepa insulin,
• kutsekereza lipolysis, komwe kumabweretsa kuchepa kwa kuchuluka kwamafuta acid m'magazi, zomwe zimakhudza kugawa kwamphamvu kwa minofu ya adipose,
• kuchepa kwa triglycerides,
• kuchuluka kwamagazi a HDL (high density lipoproteins).

Chifukwa cha zonse izi, mukamamwa mankhwalawa, chiphuphu chokhazikika cha matenda osokoneza bongo chimatheka - kuchuluka kwa shuga m'magazi kumakhala pafupifupi nthawi zonse komanso momwe wodwalayo amakhalira bwino.

Komabe, mankhwalawa amakhalanso ndi zovuta:

• glitazones ndi otsika pogwira ntchito kwa "abale" awo, omwe amagwirizana ndi magulu a sulfonylurea ndi metformins,
• rosiglitazones amaswa chifukwa cha vuto la mtima ndi mtima, chifukwa amatha kuyambitsa matenda a mtima kapena matenda a mtima (ndipo mtima wamatsenga umakhudzidwa makamaka ndi chitukuko cha matenda ashuga)
• glitazones imakulitsa chilakolako cha thupi ndikuwonjezera thupi, zomwe ndizosafunikira kwambiri pakupanga matenda a shuga a 2, chifukwa izi zimatha kudzetsa mavuto ena azaumoyo komanso kusintha kwa T2DM kupita ku T1DM.

Chifukwa cha kukhalapo kwa zotsatira zoyipa zambiri komanso ma contraindication mu mankhwalawa, ndizosatheka kuzitenga popanda kudziwa dokotala

Zizindikiro ndi contraindication

Pioglitazones ndi rosiglitazones angagwiritsidwe ntchito ngati mankhwala oyima pawekha pochiza T2DM, komanso kuphatikiza ndi sulfonylurea ndi metformin (kuphatikiza mankhwalawa kumangogwiritsidwa ntchito pa matenda oopsa). Monga lamulo, amawerengedwa pokhapokha ngati mankhwala othandizira pakudya ndi olimbitsa thupi atha kupereka zotsatira zabwino.

Choyimira chachikulu pakugwiritsira ntchito pioglitazones ndi rosiglitazones ndizotsatira zathupi lamoyo ndi zam'thupi:

• mimba ndi mkaka wa m`mawere
• wazaka 18
• lembani matenda ashuga 1 a shuga ndi zina momwe mumafunika mankhwala a insulin,
• kupitilira gawo la ALT nthawi zopitilira 2.5,
• matenda a chiwindi mu pachimake gawo.

Mankhwala "Avandia" ayenera kuyikidwa kokha ndi dokotala

Kuphatikiza pa chakuti mankhwala am'badwo watsopano awa ali ndi contraindication, amakhalanso ndi zovuta. Nthawi zambiri, akagwiritsidwa ntchito ngati odwala, zotsatirazi zimadziwika:

Mankhwala Atsopano a 2 A shuga

• Edema, mawonekedwe ake omwe amayamba chifukwa cha kuthekera kwa magwiridwe antchito a mankhwalawa kuti azitha kusunga madzi mthupi. Ndipo izi zitha kusokoneza ntchito ya mtima ndi mitsempha, kuonjezera zoopsa zomwe zingayambitse kulephera kwa mtima, kuchepa kwa mtima ndi zina zomwe zingawopseze wodwalayo.
• Kutsika kwa hemoglobin m'magazi (magazi m'thupi), omwe amadzala ndi zovuta zamkati mwaubongo, pomwe amayamba kufa ndi njala. Nthawi zambiri, chifukwa cha kuchepa kwa magazi, kumakhala kuphwanya kayendedwe kazisamba, kuchepa kwamphamvu kwa patency, kusangalala kwa CNS, ndi zina zambiri. Zinthu zonsezi zimasokoneza wodwalayo.
• Kuphwanya ntchito za michere ya chiwindi (ALT ndi AST), yomwe imakhala chifukwa chopanga chiwindi ndi kulephera kwina kwa zinthu zina.Chifukwa chake, mukamatenga pioglitazones ndi reseiglitazones, muyenera kupimidwa magazi pafupipafupi. Ndipo pamenepo

ngati kuchuluka kwa ma enzymes amenewa kumaposa kuchuluka kwa nthawi zopitilira 2.5, kuthetsedwako kwa mankhwalawa ndikofunikira.

Zofunika! Glitazones imakhudza dongosolo la kubereka, zomwe zimapangitsa kuti azimayi azisamba nthawi yayitali asanabadwe, zomwe zimawonjezera mwayi wokhala ndi pakati.

Ndipo popeza mankhwalawa amatha kupangitsa kuti pakhale zovuta zina zapakati pa mwana wosabadwayo, njira zodalirika zakulera ziyenera kugwiritsidwa ntchito nthawi zonse mukamalandira chithandizo chamankhwala.

Gulu lina latsopano la mankhwala omwe posachedwapa anayamba kugwiritsidwa ntchito pochiza matenda amtundu wa 2. Mwa izi, otchuka kwambiri ndi Exenatide ndi Sitagliptin. Monga lamulo, mankhwalawa amagwiritsidwa ntchito limodzi ndi Metformin.

• kuchuluka kwa insulin,
• malamulo apangidwe a madzi a m'mimba,
• kuchedwetsa njira za chimbudzi ndi kuperewera kwa chakudya, zomwe zimatsimikizira kuponderezedwa kwa njala ndi kuwonda.

Mukamamwa ingretinomimetics, mseru ndi m'mimba zimatha. Komabe, malinga ndi madotolo, izi zoyipa zimachitika pokhapokha pamankhwala. Thupi likangoyamba kuzolowera mankhwalawa, amazimiririka (zimatenga masiku 3-7).

Incretinomimetics ndi mankhwala amphamvu kwambiri, ndipo ngati atagwiritsidwa ntchito molakwika, amatha kuyambitsa mavuto akulu azaumoyo.

Mankhwalawa amapereka kuwonjezeka kwa insulin m'magazi ndikutchingira kapangidwe ka glucagon, chifukwa chomwe shuga mumagazi imakhazikika komanso mkhalidwe wa wodwalayo umakhala bwino. Ingretinomimetics imakhala ndi zotsatira zokhalitsa, chifukwa chake, kuti apeze zotsatira zosatha, kudya kwawo ndikokwanira kuchita nthawi imodzi yokha patsiku.

Choyipa cha mankhwalawa ndikuti samamvekanso bwino, amagwiritsidwa ntchito pazachipatala osati kale kwambiri ndipo amawononga ndalama zambiri kuposa "abale" awo.

Chithandizo cha cell cha tsinde la mtundu wachiwiri wa shuga ndi njira yodula koma yothandiza kwambiri. Amagwiritsidwa ntchito pokhapokha ngati mankhwala osokoneza bongo samapereka zotsatira.

Kugwiritsa ntchito maselo a tsinde pochiza matenda a shuga kungakwaniritse zotsatirazi:

• kubwezeretsa kwathunthu kwa ntchito za pancreatic ndi kuchuluka kwa insulin,
• kusintha kwa kagayidwe kachakudya njira,
• Kuchotsa kwa endocrine matenda.

Chifukwa chogwiritsa ntchito maselo a tsinde, zimatha kuchotsa matenda ashuga, omwe kale sanali kuzikwaniritsa. Komabe, chithandizo choterechi chili ndi zovuta. Kuphatikiza apo popeza njirayi ndi yodula kwambiri, siyimamvekanso bwino, ndipo kugwiritsa ntchito maselo am'mimba mwa wodwala kumatha kubweretsa kusintha kosayembekezereka kwa thupi.

Zomwe zimayambitsa kukula kwa matenda ashuga amtundu wa 2 ndizovuta zambiri zamafuta komanso kupsinjika, zomwe zimapangitsa kupangika kwa mahomoni m'thupi monga thyroxine ndi adrenaline. Kuti ma mahomoni awa atha kukonzedwa, thupi limafunikira mpweya wambiri, womwe mutha kupeza mulingo woyenera kudzera mukuchita zolimbitsa thupi kwambiri.

Magnetorepia imapereka kubwezeretsa kwa chapakati mantha dongosolo ndi kusintha kwa wodwalayo

Koma popeza anthu ambiri alibe nthawi yochita masewera, mahomoni awa amadziunjikira m'thupi, zomwe zimayambitsa njira zosiyanasiyana zamatumbo momwemo. Ndipo matenda a shuga a 2 ayamba kukulira.

Pankhaniyi, kugwiritsa ntchito magnetotherapy ndikothandiza kwambiri, komwe kumayendetsa ntchito ya ziwalo zonse zamkati ndikulimbikitsa kugwira ntchito kwa thyroxine ndi adrenoline, potero kuletsa kupititsa patsogolo kwa matendawa komanso kuchepetsa matenda a shuga.

Komabe, kugwiritsa ntchito magnetotherapy sikutheka nthawi zonse. Ali ndi zolakwika zake, monga:

• chifuwa chachikulu
• mimba
• hypotension
• kutentha kwambiri
• matenda oncological.

Ngakhale njira zambiri zochizira matenda amtundu wa 2 zawonekeranso ngati mankhwala, ziyenera kumveka kuti onse samamveka bwino. Kugwiritsa ntchito kwawo kungayambitse zotsatira zosayembekezereka. Chifukwa chake, ngati mukuganiza kuyesa njira zamakono zochizira matendawa nokha, lingalirani mosamala ndikukambirana zovuta zonse ndi dokotala.

Zowonjezera pathandizira popewa matenda amtundu 1 komanso matenda ashuga 2: nkhani zaposachedwa ndi njira zamakono kwambiri

Odwala omwe amapezeka ndi matenda osokoneza bongo amachititsa mosiyanasiyana "nkhani" zoterezi.

Ena amakhala ndi mantha, ena amangochita zofuna zawo ndikuyesetsa kuzolowera moyo watsopano posachedwa.

Koma mulimonsemo, aliyense wodwala matenda ashuga amakonda kuchita zinthu zatsopano, zomwe ngati simungathe kuchotsetsa matenda, siyani njira za anthu odwala matenda ashuga kwa nthawi yayitali.

Tsoka ilo, palibe njira zochiritsiratu matenda ashuga. Komabe, ndizotheka kuti, mutayesa njira zina zamankhwala zatsopano, mudzamva bwino.

Nkhani Zapadziko Lonse Zokhudza Matenda a shuga a Type 1

Monga mukudziwa, mtundu wa matenda ashuga 1 umayamba chifukwa cha kutayika kwa maselo a kapamba omwe amatha kupanga insulini.

Matenda oterewa adanenapo zofunikira komanso kukula msanga.

Kuphatikiza pa cholowa chamtsogolo, zomwe zimayambitsa matenda ashuga zimatha kukhala matenda opatsirana, kusokonezeka kwa manjenje nthawi zonse, kusagwira bwino ntchito kwa chitetezo chathupi komanso ena .ads-mob-1

M'mbuyomu, kuukira kwa matenda a shuga a mtundu woyamba kunali kotheka ndi jakisoni wa insulin. Posachedwa, zopambana zachitika m'derali.

Tsopano matenda a shuga a Type 1 amatha kuthandizidwa pogwiritsa ntchito njira zatsopano, zomwe zimagwiritsidwa ntchito pakugwiritsa ntchito maselo a chiwindi osinthika ndikutha kwawo kutulutsa insulin pansi pazinthu zina.

Insulin Yopitilira - Kupambana Kwambiri Kwambiri

Monga mukudziwa, insulin yamakono, yomwe imagwiritsidwa ntchito ndi anthu odwala matenda ashuga, imatenga nthawi yayitali, ikuthandizira kuchepa kwapang'onopang'ono m'magawo a shuga, komanso kuthamanga.

Kuti khazikike bwino, odwala amagwiritsa ntchito mitundu yonse iwiri ya mankhwala. Komabe, ngakhale kuphatikiza mwaluso kwa mndandanda wa mankhwalawo sikuloledwa kupeza mphamvu yayitali.

Chifukwa chake, kwa zaka zambiri, insulin yopitilira idakhala loto kwa odwala matenda ashuga. Posachedwa, asayansi adakwanitsabe kusintha.

Zachidziwikire, sikuti insulini yokhazikika, zikutanthauza kuperekedwa kamodzi kwa mankhwalawo. Komabe, njira iyi ndi gawo lalikulu patsogolo. Tikukamba za insulin yochita zinthu kwa nthawi yayitali, yopangidwa ndi asayansi aku America.

Kupitiliza kwa nthawi yayitali kumatheka chifukwa cha kuphatikiza polymer pazomwe zimapangidwira, zomwe zimaloleza kupereka thupi ndi mahomoni GLP-1.ads-mob-2 ofunikira kuti akhale athanzi

Kuika mafuta kwamafuta

Kuyesaku kunachitika pa makoswe a labotale, ndipo kugwira ntchito kwake kunali kwodziwikiratu.

Pambuyo pochulukitsa, kuchuluka kwa glucose m'thupi kunachepa ndipo sikunawonjezeke pakapita nthawi.

Zotsatira zake, thupi silifunanso insulin yayikulu.

Ngakhale zili ndi zotulukapo zabwino, malinga ndi asayansi, njirayi imafunikira zowonjezera zowerengera ndi kuyesa, zomwe zimafuna ndalama zambiri.

Kusintha kwa maselo a tsinde kukhala maselo a beta

Madotolo adatha kutsimikizira kuti kuyambika kwa matenda ashuga kumachitika pamene chitetezo cha mthupi chimayamba kukana maselo a beta omwe amayambitsa kupanga insulin mu kapamba.

Komabe, posachedwa, asayansi adatha kuzindikira ma cell ena a beta mthupi, omwe, malinga ndi akatswiri, ngati atagwiritsidwa ntchito moyenera, atha kusintha kwathunthu mlengalenga womwe wakanidwa ndi chitetezo chamthupi.

Zinthu zina zatsopano

Palinso zinthu zina zatsopano zopangidwa polimbana ndi matenda a shuga.

Njira imodzi yotsogolera, yomwe akatswiri pakadali pano ali ndi chidwi chachikulu ndi kupeza maselo atsopano a pancreatic pogwiritsa ntchito 3D kusindikiza kwa zimakhala zatsopano.

Kuphatikiza pa njira yomwe tafotokozayi, chitukuko cha asayansi aku Australia chimafunikanso chisamaliro chapadera. Adapeza kupezeka kwa hormone GLP-1, yomwe imayang'anira kupanga insulin, poyizoni wa echidna ndi pulypus.

Malinga ndi asayansi, mu nyama, zochita za timadzi timeneti zimaposa zochita za anthu pankhani ya kukhazikika. Chifukwa cha izi, zinthu zomwe zimachotsedwa poizoni wa nyama zitha kugwiritsidwa ntchito bwino popanga mankhwala atsopano a antiidiabetes.

Zatsopano mu Type 2 Shuga

Ngati tikulankhula za matenda a shuga a mtundu wachiwiri, chifukwa cha kukhazikika kwa matendawa ndi kutaya mwayi wogwiritsa ntchito ma insulin ndi maselo, zomwe zimapangitsa kuti shuga wambiri komanso mahomoni omwewo athe kudziunjikira m'thupi.

Malinga ndi madotolo, chifukwa chachikulu cha kusamvetseka kwa thupi ku insulini ndikudzikundikira kwa lipids mu chiwindi ndi minofu ya minofu.

Poterepa, kuchuluka kwa shuga kumakhalabe m'magazi. Anthu odwala matenda ashuga omwe ali ndi matenda amtundu wachiwiri amagwiritsa ntchito jakisoni wa insulin kawirikawiri. Chifukwa chake, kwa iwo, asayansi akupanga njira zosiyana pang'ono kuti athetse zomwe zimayambitsa matenda.

Njira yopatukana ndi mitochondrial

Njirayi idakhazikitsidwa pachiweruziro kuti chifukwa chachikulu chakukhazikitsidwa kwa matenda am'mimba ndikuwunjikana kwa lipids mu minofu ndi maselo a chiwindi.

Pankhaniyi, asayansi adagwira ntchito yochotsa mafuta owonjezera mumthupi mu minofu pogwiritsa ntchito kukonzanso kosinthika (imodzi mwazinthu za FDA). Chifukwa cha kuchepa kwa lipid, khungu limabwezeretsanso kudziwa insulin.

Pakadali pano, mankhwalawa akuyesedwa bwino mwa zolengedwa zomwe zimayamwa. Komabe, ndizotheka kuti kwa munthu zitha kukhala zothandiza, zothandiza komanso zotetezeka.ads-mob-1

Incretins - gawo lofunikira kwambiri pamankhwala

Ma insretins ndi mahomoni omwe amalimbikitsa kupanga insulin. Kumwa mankhwala a gululi kumathandiza kuchepetsa kuchuluka kwa shuga m'magazi, kukhazikika pathupi, kusintha kwabwino mu mtima ndi m'mitsempha yamagazi.

Ma insretins samachotsa kukula kwa hyperglycemia.

Glitazones ndi mankhwala atsopano omwe amapangidwira kuti chiwonjezere mphamvu za maselo kuti apange insulin.

Mapiritsi amatengedwa panthawi ya chakudya ndikutsukidwa ndi madzi. Ngakhale kuti Glitazones imapereka zotsatira zabwino, ndizosatheka kuchiritsa matenda a shuga pogwiritsa ntchito mapiritsi ngati amenewo.

Komabe, kugwiritsa ntchito mankhwala mosalekeza kuchokera ku gululi kumapangitsa kuti pakhale zovuta: edema, fragility mafupa, kulemera.

Maselo a tsinde

Kuphatikiza pa kugwiritsa ntchito mankhwala ochepetsa shuga, mankhwalawa athetse matenda am'mimba sangakhale othandiza pakulimbana ndi matenda a shuga a mtundu wachiwiri.

Njirayi imaphatikizapo magawo awiri. Choyamba, wodwalayo amapita kuchipatala, komwe amakamwa kuchuluka kwa zinthu zachilengedwe (magazi kapena magazi a ubongo).

Kenako, maselo amatengedwa kuchokera ku gawo lomwe adatengedwa ndikufalikira, ndikuchulukitsa kuchuluka kwawo pafupifupi kanayi. Pambuyo pake, maselo omwe angobadwa kumene amalowetsedwa m'thupi, pomwe amayamba kudzaza malo owonongeka a zimakhala.

Magnetotherapy

Matenda a shuga a Type 2 amatha kuthandizidwa ndi magnetotherapy. Kuti muchite izi, gwiritsani ntchito chipangizo chapadera chomwe chimatumiza mafunde pamagetsi.

Magetsi amakhudzidwa amakhudza ntchito ya ziwalo zamkati ndi machitidwe ake (mu izi, mitsempha yamagazi ndi mtima).

Mothandizidwa ndi mafunde a maginito pali kuwonjezeka kwa kayendedwe ka magazi, komanso kuphatikizidwa ndi mpweya. Zotsatira zake, kuchuluka kwa shuga motsogozedwa ndi mafunde a zida zamagetsi kumachepa.

Mankhwala amakono kuti muchepetse shuga

Mankhwala amakono omwe amathandizira kuchepetsa shuga m'magazi amaphatikiza Metformin kapena Dimethyl Biguanide.

Mankhwalawa amathandizira kuchepetsa shuga m'magazi, kumapangitsa kuti maselo azikhala ndi insulini, komanso kuchepetsa kuyamwa kwa shuga m'mimba ndikuthandizira kuthana ndi oxidation wamafuta acids.

Kuphatikiza ndi wothandiziridwayo, Glitazone, insulin ndi sulfonylureas angagwiritsidwenso ntchito.

Kuphatikiza kwa mankhwalawa sikungangopeza zotsatira zabwino, komanso kuphatikiza zotsatira.

Zomwe zapezedwa posachedwa popewa matenda

Ngakhale pali njira zingapo zopangira nzeru, njira yothandiza kwambiri yopezera thanzi ndikutsatira zakudya.

Ndikofunikanso kuiwala za kusiya zizolowezi zoyipa komanso kuyezetsa magazi pafupipafupi kwa shuga kuti pakhale cholowa chotengera chitukuko cha matenda a shuga.ads-mob-2

About njira zatsopano zochizira matenda amtundu 1 ndi mtundu wachiwiri wa shuga mu kanema:

Ngati mwapezeka kuti muli ndi matenda a shuga, ndipo mukufuna kuyesa imodzi mwazomwe mungapangire chithandizo, dziwitsani dokotala kuti adziwe za matendawa. Ndizotheka kuti mitundu iyi ya mankhwalawa ithandizira kupeza zotsatira zomwe mukufuna ndikuchotsa matenda a hyperglycemia kwa nthawi yayitali.

Zizindikiro ndi zomwe zimayambitsa matenda ashuga

Pali mitundu iwiri yamatenda:

• mtundu woyamba (umabuka ngati pali chibadwa cha njira yolowera m'malo mwatsopano),
• mtundu wachiwiri (wokhala ndi chibadwa, mnjira yayikulu).

Kuphatikiza pa zolephera za cholowa, pali zinthu zina zomwe zikuyambitsa matenda a shuga a 2:

• antibodies a m'magazi,
• kagayidwe kachakudya matenda
• kunenepa
• atherosulinosis
• matenda a mtima
• ovary polycystic,
• ukalamba
• zopsinjika pafupipafupi
• moyo wamakhalidwe.

Zizindikiro za matendawa sizimawoneka nthawi yomweyo, ndipo nthawi zambiri vuto limatha kupezeka pokhapokha ngati magazi akuyeserera. Komabe, kukhalapo kwa zizindikiro zotsatirazi, ndikofunikira kuchita zonse zofunika. Izi zikuphatikiza:

Zosokoneza zowonekera ziyenera kumchenjeza munthuyo.

• kuwonongeka kwamawonekedwe
• njala yosatha ndi ludzu
• pafupipafupi matenda obeleka
• Fungo la acetone kuchokera mkamwa komanso mkodzo,
• kuwonongeka kwa zinthu,
• kuwonda mwadzidzidzi.

Asayansi atsimikizira kuti anthu amtundu wa Caucasus ndiwomwe angakhudzidwe padziko lonse lapansi.

Mankhwala opatsa chidwi

Njira zatsopano zothandizira odwala matenda ashuga ndi zina mwazinthu zachipatala zomwe zimapangidwa kwambiri. Zatsopano zomwe zimachitika kwa odwala matenda ashuga zimatha kukhala njira yabwino komanso njira yochotsera vutoli mwachangu popanda chofufuza. Osati maukadaulo onse awa omwe amawonedwa mozama, ndipo ena amawonedwa ngati osachita. Komabe, musasokoneze mankhwala aposachedwa kapena katemera, omwe angagwiritsidwe ntchito pochiza matenda amtundu wa 2, ndi mankhwala ena.

Mankhwala amakono

Chithandizo cha matenda ashuga sichingachitike popanda kugwiritsa ntchito mankhwala. Mankhwala amapereka mitundu yambiri ya mankhwala, koma si onse omwe amatha kuthetsa zomwe zimayambitsa matenda ashuga, ndipo mankhwalawo ndi othandiza, ndikofunikira kuthetsa zomwe zimayambitsa. Kufufuza zamankhwala aposachedwa kumadalira kuphatikiza kwa mankhwala omwe amadziwika kale. Njira yamakono yothandizira mankhwalawa pochiza matenda amtundu wa 1 kapena matenda a 2 amachitika m'magawo atatu:

• kugwiritsidwa ntchito kwa "Metformin" kapena "Dimethylbiguanide", komwe kumachepetsa shuga la magazi ndikuwonjezera chidwi cha minofu pazinthu,
• kugwiritsa ntchito mitundu yomweyo ya mankhwala ochepetsa shuga,
• ngati palibe kusintha komwe kumachitika, mankhwala a insulin amachitika.

Bweretsani ku zomwe zalembedwa

Kuthira mafuta omwe sichoncho?

Njira ina yosachiritsika yochizira “matenda otsekemera” ndi kufalikira kwa mafuta a bulauni. Ichi ndi chimodzi mwazomwe minofu yomwe nyama ndi ana akhanda amakhala nazo khosi la impso, masamba ndi kumbuyo. Kuika chinthu ichi kumatha kuchepetsa kufunika kwa insulini, kusintha kagayidwe ka chakudya chifukwa cha kuchuluka kwa mamolekyulu am'magazi a lipid maselo a bulauni a adipose minofu. Komabe, pakadali pano, njirazi zimawonedwa ngati zosafunikira ndipo zimafunikira kafukufuku wina.

Katemera wamavuto - kuchira ndikotheka

Zatsopano pothandizira matenda a shuga zimapereka ntchito jakisoni wapadera womwe ungalepheretse chitukuko cha matendawa. Njira yochitira mankhwalawa ndi "kuphunzitsa": mankhwalawa omwe adalowetsedwa amateteza mphamvu ya chitetezo cha mthupi kuwononga ma cell a B ndikusintha pang'ono pang'ono za DNA. Mamolekyulu osinthidwa amasiya njira zotupa, chifukwa chake, matenda ashuga amayamba kupita patsogolo.

Kuchiritsa bongo?

Chithandizo cha matenda ashuga, omwe cholinga chake ndi kukonza mkhalidwe wa wodwalayo, kusintha matenda a shuga komanso kuteteza maselo a B, amatchedwa orthomolecularapy pamankhwala. Njirayi imaphatikizapo kudya kwa mlingo waukulu wa zinthu zapadera, monga ma amino acid a shuga, mavitamini ndi michere yambiri. Zinthu zoterezi ndizofunikira kuti muchiritse bwino matenda ashuga. Amalowa mkati mwa thupi pogwiritsa ntchito mitundu yosiyanasiyana: ufa, kuyimitsidwa, mapiritsi.

Palibe maphunziro omwe akuwatsimikizira kuti njirayi ndiyothandiza.

Zida zachilendo zamankhwala

Njira ina yothandizira masiku ano anthu odwala matenda ashuga ndi kugwiritsa ntchito zida zapadera zomwe zimathandizira kukonza kagayidwe kazinthu komanso kuchepetsa matenda a shuga. Mutha kupeza zida zotere m'magulu ena azachipatala ndikugwiritsa ntchito pokhapokha mukaonana ndi dokotala. Katswiriyo amasankha chida chayekha ndi kudziwa mtundu wa momwe adzagwiritsidwire ntchito.

Magnetoturbotron

Pogwiritsa ntchito chipangizo chapadera, ndizotheka kusintha momwe wodwalayo alili: kusintha magwiridwe antchito a kagayidwe kachakudya pogwiritsa ntchito mphamvu ya maginito. Chipangacho chokha chimapangidwa mwa mawonekedwe a kapisozi, okhala ndi ma sensors apadera omwe amayikidwa mkati momwe omwe amatha kulowa mkati mwakuya kwamtundu uliwonse.

Tekinoloje yatsopano pothandiza odwala matenda ashuga

Pampu ya insulin ndi yaying'ono (kukula kwa foni) chida chamakompyuta chachipatala. Chifukwa cha kukula kwake kocheperako, chipangizocho chimakhala choti sichingawonongeke pansi pazovala, ndizosavuta kunyamula mthumba kapena lamba.

Ntchito yayikulu ya pampu ndikuwongolera mosalekeza kwa insulin yochepa-yochepa yochita kumafuta amkati. Mankhwalawa amawadyetsa kudzera mu chubu chapulasitiki chosinthika - catheter, yomwe imayikidwa pogwiritsa ntchito jakisoni wapadera ndikukhazikika m'malo mwake ndi gulu lothandizira.

Njira yoyendetsera insulin yogwiritsira ntchito pampu imafanana ndi ntchito ya kapamba wama thanzi. Kuti muzitsatira mwachizolowezi insulin yotsekera pakati pa chakudya ndi usiku, chipangizocho chimaperekabe mosamala mankhwalawa yaying'ono. Kuchuluka kwa mankhwalawa omwe amathandizira kumakonzedweratu ndi adokotala omwe amapita malinga ndi zosowa za wodwalayo. Asanadye, wodwalayo amadzivulaza payekha kuchuluka kwa insulin ndikanikizira batani pampu. Izi zimatchedwa bolus. Mapampu amakono ali ndi "mlangizi wa" wa bolus - pulogalamu yomanga yomwe imakuuzani mtundu wa insulin wabwino kubaya. Pogwiritsa ntchito pampu, insulini imatha kugawidwa bwino kwambiri kuposa syringe. Kuphatikiza apo, mapampu ambiri amakhala ndi chipangizo chowunikira mosamala kuchuluka kwa shuga mumagazi ndikuzimitsa pomwe glycemia ikucheperachepera. Catheter ya pampu imayenera kusinthidwa kamodzi masiku atatu - kotero palibe chifukwa chobayira zingapo.Chithandizo cha insulin ndi njira yofunika kwambiri yothandizira thupi mpaka pano. Chokhacho chingabweze njira iyi ndi mtengo wokwera wa chipangizocho ndikuwukonza.

Njira zowunikira mosamala kuchuluka kwa shuga m'magazi - CGMS (Njira zowunikira shuga)

Njira yokhazikika yowunikira kuchuluka kwa shuga m'magazi imakhala ndi magawo atatu:

1) Sensor yaching'ono yomwe imayikidwa pang'onopang'ono. Kugwiritsa ntchito, pafupifupi masekondi 10 aliwonse, kuchuluka kwa glucose m'madzi am'mimba kumatsimikiziridwa, pambuyo pake idatha imafalikira kwa polojekiti. Sensor imatha kukhala m'mafuta amkati kwa masiku 3-5, pambuyo pake iyenera kusintha.

2) Wowunikira ndi chipangizo chamakompyuta chomwe chimalemba ndi / kapena kuwonetsa munthawi yake kuchuluka kwa shuga m'magazi. Kuti akhazikitse polojekiti, muyenera kuyeza shuga nthawi 4-5 patsiku pogwiritsa ntchito glucometer ndikulowetsa chipangizocho.

3) Mawaya omwe amalumikiza sensor ndi polojekiti. Komabe, muma CGMS ena amakono deta imafalitsidwa pogwiritsa ntchito ma wayilesi.

Kuti mufufuze zomwe mwalandirazi pogwiritsa ntchito pulogalamu yapadera. Zotsatira za phunziroli zitha kuperekedwa, zonse mwa mawonekedwe a ma graph, komanso mawonekedwe a zithunzi zomwe zimawonetsa kusinthasintha kwa glucose m'magazi. Ndikofunikira kulemba mu diary zochitika zonse zomwe zimakhudza shuga wamagazi: nthawi ya kudya ndi kuchuluka kwa chakudya chomwe mumadya, kumwa mankhwala, kugona, chidziwitso chokhudza zochitika zolimbitsa thupi kuti muchepetse kusanthula kwa deta.

CGMS ndiyofunikira kwambiri kuti tipeze hypoglycemia yam'mbuyo komanso yamadzulo, "kusinthasintha kwa m'mawa", kusinthasintha kwa shuga chifukwa chakuphwanya zakudya kapena mapiritsi a insulin osankhidwa bwino.

Kukonzekera kwa insulini kuvomerezedwa kuvomerezedwa kwa zaka zingapo ku USA. Odwala amapaka ufa wowuma pogwiritsa ntchito chipangizo chapadera, pambuyo pake mankhwalawo amadziwidwa mwachindunji m'magazi. Makulidwe a insulini amapewa majakisoni ambiri. Kafukufuku wachipatala akuwonetsa kuti kugwiritsa ntchito njira iyi poperekera mankhwala kumakupatsani mwayi wokwaniritsa matenda a glycemia a mtundu 1 a shuga mu 80% ya milandu. Zowona, insulin yolowerera imakhala ndi zovuta zingapo: kulondola kochepa kwambiri, kulephera kugwiritsa ntchito kwa omwe amasuta komanso omwe ali ndi matenda apamwamba a thirakiti. Ngakhale kuti njirayi imafunikabe kusintha, ndiyabwino. Munthu akhoza kungoyembekezera pamene mankhwalawa avomerezedwa kuti azigwiritsidwa ntchito mdziko lathu.

Kukhazikitsa mankhwala atsopano ochepetsera shuga akuchitika kwambiri padziko lonse lapansi. Kupeza kwasayansi m'zaka khumi zapitazi kunali kupezeka kwa gulu latsopanolo la mankhwala - incretinomimetics.

Ma insretins ndi mahomoni achilengedwe omwe amasungidwa ndi maselo am'mimba poyankha zakudya zomwe zimakhala ndi zakudya. Izi zimaphatikizapo glucagon-like peptide-1 (GLP-1) ndi glucose-wodalira insulinotropic polypeptide (HIP). Kulowa m'magazi - zinthuzi zimakhudza gawo lakumapazi, kumalimbikitsa kupanga insulin. Kuphatikiza apo, amachepetsa kubisalira kwa glucagon, mahomoni omwe amalimbikitsa kutulutsa shuga m'magazi kuchokera pachiwindi, ndikuchepetsa kutsika kwam'mimba, zomwe zimapangitsa kuti akhale ndi chiyembekezo chokwanira.

Zimatsimikizika kuti odwala omwe ali ndi matenda a shuga a mtundu wachiwiri, amapanga mankhwala omwe amapanga okha. Izi zili choncho chifukwa chakuti ma insretin amawonongeka msanga motsogozedwa ndi enzyme DPP-4 (dipeptidyl peptidase-4). Pali magulu awiri a mankhwalawa: DPP-4 zoletsa zomwe zimapangitsa kuti nthawi yayitali zizungulire zomwe zimafunikira, komanso mawonekedwe a GLP-1 omwe sagwirizana ndi zomwe enzymeyi ikuchita.Kafukufuku akuwonetsa kuti mankhwalawa amtundu wa incretin amachepetsa HbA1c ndi 0.5% -1%, amathandizira kuchepetsa thupi ndipo samayambitsa hypoglycemia.

Pramlintide (syntyl amylin)

Pramlintide ndi analogue amylin, timadzi tamapuloteni timene timasungidwa m'magazi ndi ma pancreatic β-cell limodzi ndi insulini poyankha kudya. Odwala omwe ali ndi matenda amtundu wa shuga ndimelitus, katulutsidwe ka amylin pafupifupi sapezeka kwathunthu (komanso insulin). Kugwiritsa ntchito kupanga amylin kuphatikiza ndi mankhwala a insulin kumalumikizidwa ndi kuchepa kwa hemoglobin wa glycated ndi kuchepa thupi. Pramlintide imathandizira kuti pakhale nthawi yayitali kuti muzitha kumverera, imachepetsa kutsanulira kwam'mimba ndipo imalepheretsa chinsinsi cha shuga. Analogue yopanga ya amylin ivomerezedwanso ndipo yakhala ikugwiritsidwa ntchito bwino ku United States kuyambira 2009 pochiza matenda amtundu wa 1 komanso mtundu wa 2 wodwala mellitus osakanikirana ndi insulin.

Kuphatikiza apo, pali njira zambiri zosangalatsa zomwe, popanda kukokomeza, zitha kuikidwa pakati pa matekinoloje amtsogolo. Chifukwa, mwachitsanzo, kachilombo kamalengedwa pogwiritsa ntchito bioengineering, matenda atatha, maselo am'mimba amayamba kupanga insulin. Gulu lina la ofufuza adapanga magalasi amalumikizidwe omwe amayesa kuchuluka kwa shuga m'matumba a misozi ndikufalitsa chidziwitsochi pafoni yam'manja. Ntchito yayikulu ikuchitika kuti apange kapamba wochita kupanga. Mwina posachedwa ena mwaukadaulo awa adzakwaniritsidwa ndipo azithandiza anthu mamiliyoni ambiri omwe ali ndi matenda ashuga.

CS Medica, 1998-2019
Maumwini onse ndi otetezedwa.

Chithandizo chatsopano cha matenda ashuga: zatsopano ndi mankhwala amakono pazamankhwala

Masiku ano, mankhwala amakono apanga njira zingapo zochizira matenda ashuga. Chithandizo chamakono cha matenda ashuga chimaphatikizapo kugwiritsa ntchito njira zosiyanasiyana, zamankhwala komanso zolimbitsa thupi m'thupi la wodwala wokhala ndi matenda amtundu wa 2.

Akazindikiridwa m'thupi, atazindikira kuti ali ndi matenda ashuga, monotherapy imayikidwa koyamba, yomwe imakhala ndi kutsatira mosamalitsa zakudya. Zikachitika kuti njira zomwe wodwala yemwe ali ndi matenda a shuga azikwanira sizokwanira, ndiye kuti mankhwalawa amasankhidwa ndikusankhidwa kuti agwiritse ntchito, zomwe zimapangitsa kuchepetsa kuchuluka kwa shuga m'magazi.

Mankhwala ena amakono samachotsa kuthekera kwa kudya chakudya chamafuta. Kugwiritsa ntchito mankhwalawa kwa mtundu wachiwiri wa matenda a shuga kumathandizira kupewa kukula kwa chikhalidwe cha hypoglycemic mwa anthu.

Mankhwala amasankhidwa ndipo njira yolandirira odwala imapangidwa malinga ndi momwe munthu akuvutikira ndi matenda a shuga a 2 komanso deta yomwe imapezeka panthawi yoyeserera wodwalayo.

Kusankha kwamankhwala ndi cholinga chake

Njira zakuchiritsira zamakono za mtundu wachiwiri wa matenda ashuga zimaphatikizanso kugwiritsa ntchito njira zosiyanasiyana zowongolera shuga m'thupi la wodwalayo panthawi yamankhwala. Chofunikira kwambiri pazamankhwala ndi kusankha kwa mankhwala komanso mankhwala omwe amagwiritsidwa ntchito pochiza matenda amtundu wa 2 shuga.

Chithandizo chamakono cha matenda ashuga amtundu wa 2 mothandizidwa ndi mankhwala sichithetsa zofunikira pakukhazikitsa malangizo omwe akufuna kusintha moyo wawo wodwala.

Mfundo zamankhwala othandizira kudya ndi:

1. Kutsatira malamulo a zakudya zopatsa thanzi. Muyenera kudya katatu pa tsiku. Kudya kuyenera kuchitidwa m'magawo ang'onoang'ono, kutsatira dongosolo lomwelo la chakudya.
2. Ngati onenepa kwambiri, mumagwiritsa ntchito zakudya zamafuta ochepa.
3. Kuchulukitsa zakudya, zomwe zimakhala ndi fiber yambiri.
4. Kuchepetsa kudya zamafuta ambiri.
5. Kuchepetsa kudya zamchere tsiku lililonse.
6. Kusiyanitsa ndi zakumwa ndi zakumwa zoledzeretsa.
7. Kuchulukitsa zakudya zamafuta ambiri.

Kuphatikiza pa chithandizo chamankhwala pothana ndi matenda a shuga a 2, maphunziro a thupi amagwiritsidwa ntchito mwachangu. Zochita zolimbitsa thupi zimalimbikitsidwa kwa odwala omwe ali ndi matenda amtundu wa 2 mu mawonekedwe amtundu womwewo wa kuyenda, kusambira ndi kuyendetsa njinga.

Mtundu wa zochitika zolimbitsa thupi komanso kulimba kwake zimasankhidwa payekha kwa wodwala aliyense yemwe ali ndi matenda a shuga a mtundu wa 2. Ganizirani posankha katunduyu:

• zaka odwala
• zambiri za wodwala
• kukhalapo kwa zovuta ndi matenda owonjezera,
• zolimbitsa thupi zoyambira, etc.

Kugwiritsa ntchito zamankhwala pochiza matenda ashuga kumakupatsani mwayi wowonekera wa glycemia. Maphunziro azachipatala omwe amagwiritsa ntchito njira zamakono zochizira matenda osokoneza bongo amatilola kunena motsimikiza kuti zolimbitsa thupi zimathandizira kuti shuga agwiritsidwe ntchito ka plasma, kutsitsa chidwi chake, kumapangitsa kagayidwe ka lipid m'thupi, kuletsa kukula kwa matenda a shuga a shuga.

Chithandizo cha matenda ashuga

Musanaphunzire momwe njira zatsopano zakugwirira ntchito pochizira matenda a shuga 2 zimagwirira ntchito, muyenera kuphunzira momwe mtundu wa 2 wodwala amathandizidwira pogwiritsa ntchito njira yakale.

Lingaliro la chithandizo ndi njira yachikhalidwe limapangidwa poyang'anira mwamphamvu shuga wambiri m'thupi la wodwalayo, poganizira za momwe thupi limakhalira ndi machitidwe a matendawa.

Pogwiritsa ntchito njira yachikhalidwe, chithandizo cha matendawa chimachitika njira zonse zodziwira matenda zitachitika. Akalandira chidziwitso chazonse zokhudzana ndi thupi, adotolo amakupatsani chithandizo chamankhwala ndikusankha njira yoyenera kwambiri kwa wodwalayo.

Chithandizo cha matendawa pogwiritsa ntchito njira zachikhalidwe chimaphatikizira kugwiritsa ntchito nthawi imodzi mankhwalawa, mwachitsanzo, mtundu 1 wa shuga, zakudya zapadera zamagulu, masewera olimbitsa thupi, kuphatikiza apo, mankhwala apadera ayenera kumwedwa ngati gawo la mankhwala a insulin.

Cholinga chachikulu chomwe ndimagwiritsidwe ntchito a matenda a shuga ndikuchotsa chizindikiro chomwe chimawoneka pamene kuchuluka kwa shuga m'magazi kukwera kapena pamene kugwera kwambiri pansi pazomwe zimachitika. Mankhwala atsopano opangidwa ndi akatswiri opanga mankhwala amapangitsa kuti pakhale shuga wambiri m'thupi la wodwalayo akamagwiritsa ntchito mankhwala.

Njira zachikhalidwe zochizira matenda ashuga zimafuna kugwiritsa ntchito njira yachikhalidwe kwakanthawi yayitali, nthawi yamankhwala ingatenge zaka zingapo.

Mtundu wofala kwambiri wamatenda ndi matenda ashuga 2. Kuphatikiza mankhwala amtunduwu wa shuga kumafunikanso kugwiritsidwa ntchito kwa nthawi yayitali.

Kutalika kwakanthawi kothandizidwa ndi njira yachikhalidwe kumakakamiza madokotala kuyamba kufunafuna njira zatsopano zochizira matenda ashuga komanso mankhwala aposachedwa kwambiri pochiza matenda amtundu wa 2, omwe adzafupikitsa nthawi yayitali.

Pogwiritsa ntchito zomwe zapezeka mu kafukufuku wamakono, lingaliro latsopano lothandizira matenda a shuga lapangidwa.

Kupanga njira zamankhwala mukamagwiritsa ntchito njira zatsopano ndikusintha njira munthawi ya chithandizo.

Njira zamakono zochizira matenda amitundu iwiri

Kafukufuku wamakono akuonetsa kuti pochiza matenda amtundu wa 2 shuga, nthawi yakwana yoti asinthe lingaliro. Kusiyana kwakuthupi komwe matenda amakono amakuyerekeza ndi miyambo ndikuti, kugwiritsa ntchito mankhwala amakono ndi njira zamankhwala, mwachangu momwe zingatherere matenda a glycemia m'thupi la wodwalayo.

Israeli ndi dziko lomwe lili ndi mankhwala otsogola.Yoyamba yokhudza njira yatsopano yovomerezeka idakambidwa ndi Dr. Shmuel Levit, yemwe amagwira ntchito kuchipatala cha Asud ku Israel. Kuchita bwino kwa Israeli pakuchiza matenda a shuga ndi njira yatsopanoyo kudavomerezedwa ndi Komiti Yadziko Lonse Yazachipatala pakuzindikira matenda ndi matenda a shuga.

Kugwiritsira ntchito njira yachikhalidwe yochiritsira poyerekeza ndi yamakono kuli ndi zovuta zina, zomwe zimapangitsa kuti njira yogwiritsira ntchito njira yachikhalidwe ndiyosakhalitsa, nthawi zina ndikofunikira kubwereza maphunziro a chithandizo.

Akatswiri a endocrinology amasiyanitsa magawo atatu akuluakulu mankhwalawa mtundu wa 2 matenda a shuga, omwe amapereka njira yamakono yochizira matenda a kagayidwe kazakudya m'thupi.

Kugwiritsa ntchito metformin kapena dimethylbiguanide - mankhwala omwe amachepetsa shuga m'thupi.

Zochita za mankhwala ndi izi:

1. Chidacho chimapereka kuchepa kwa kuchuluka kwa shuga m'magazi a m'magazi.
2. Kuchulukitsa chidwi kwa maselo mu minofu yodalira insulini kupita ku insulin.
3. Kupereka kuthamanga kwa shuga kwa maselo pakufalikira kwa thupi.
4. Kuthamanga kwa mafuta acid oxidation njira.
5. Kuchepetsa shuga m'mimba.

Kuphatikiza ndi mankhwalawa, mutha kugwiritsa ntchito njira zamtunduwu monga:

• insulin
• glitazone
• Kukonzekera kwa sulfonylurea.

Kutheka kokwanira kumatheka pogwiritsa ntchito njira yatsopano yothandizira mankhwalawa pochulukitsa mulingo wa mankhwala pakapita nthawi pofika 50-100%

Protocol yamankhwala mogwirizana ndi njira yatsopano imalola mwayi wophatikiza mankhwala omwe ali ndi zotsatira zomwezo. Zipangizo zamankhwala zimakupatsani mwayi wothandizira panthawi yochepa kwambiri.

Zochita zomwe zimagwiritsidwa ntchito mankhwalawa zimapangidwa kuti zisinthe momwe mankhwalawo amachitikira, kuchuluka kwa insulin komwe kumapangidwa ndi kapamba, ndikumachepetsa insulin.

Mankhwala ochizira matenda a shuga a 2

Nthawi zambiri, kugwiritsa ntchito mankhwala osokoneza bongo molingana ndi njira yamakono imagwiritsidwa ntchito kumapeto kwa chitukuko cha matenda ashuga a mtundu 2.

Choyamba, pakupereka mankhwala, mankhwala amathandizidwa kuti achepetse kuthana ndi shuga kuchokera m'matumbo a lumen ndikukhazikika kwa glucose omwe amatengedwa ndi ma cell a chiwindi ndikusintha chidwi cha insulin yodalira insulin.

Mankhwala omwe amagwiritsidwa ntchito pochiza matenda a shuga akuphatikizanso mankhwala a magulu otsatirawa:

• khwawa
• khalimon
• mankhwala a sulfanilurea a m'badwo wachiwiri, etc.

Kuchiza ndi mankhwala kumaphatikiza kumwa monga:

• Bagomet.
• Metfogama.
• Fomu.
• Diaformin.
• Glformin.
• Avandia
• Aktos.
• Diabeteson MV.
• Ziphuphu.
• Maninil.
• Glimax
• Amaril.
• Glimepiride.
• Glybinosis achigonjetse.
• Novonorm.
• Starlix.
• Dziwani.

Woopsa matenda, alpha-glycosidase ndi fenofibrate inhibitors amagwiritsidwa ntchito pochiza. Mankhwala ochizira amasankhidwa ndi endocrinologist yemwe amadziwa mawonekedwe a matendawa mwa wodwala wina. Mankhwala aliwonse ayenera kuperekedwa kwa odwala pokhapokha ndi dokotala yemwe wapanga chithandizo chachikulu. Endocrinologists a ku Russia amadziwa bwino njira yatsopano yothandizira.

Mdziko lathu, odwala ayamba kuchitira odwala monga njira za madotolo aku Israeli, kusiya njira zachikhalidwe.

Kutchulidwa kwamagulu a mankhwala omwe amagwiritsidwa ntchito pa matenda ashuga

Mankhwala a gulu la Biguanide adayamba kugwiritsidwa ntchito zaka zoposa 50 zapitazo. Choipa cha mankhwalawa ndichotheka kwambiri mawonekedwe awo a lactic acidosis. Buformin ndi phenformin ali m'gulu la mankhwalawa.Kuperewera kwa mankhwala m'gululi kunapangitsa kuti asatengedwe m'maiko ambiri mndandanda wazololedwa. Chithandizo chokhacho chovomerezedwa kuti chigwiritsidwe ntchito mgululi ndi metformin.

Kuchita kwa mankhwalawa kumachitika chifukwa cha njira zingapo zomwe sizimagwirizana ndi njira ya insulin yotulutsidwa ndi beta cell ya kapamba. Metformin imatha kupondereza kupanga kwa glucose ndi ma cell a chiwindi pamaso pa insulin. Kuphatikiza apo, mankhwalawa amatha kuchepetsa kukonzekera kwa insulin.

Njira yayikulu yogwiritsira ntchito m'badwo watsopano wa sulfonylureas ndi kukondoweza kwa insulin. Anamwino a gululi amagwira ntchito pama cell apancreatic, kuwonjezera luso lawo lachinsinsi.

Mothandizidwa ndi mankhwala, mankhwalawa sulfonylureas amayamba ndi otsika kwambiri Mlingo, ndipo Mlingo umawonjezereka ndi mankhwala ena pokhapokha ngati pakufunika.

Zotsatira zoyipa zogwiritsidwa ntchito ndi mankhwalawa ndizotheka kwakukulu kwakatukuka kwa vuto la hypoglycemia m'thupi la wodwalayo, kuchuluka kwa thupi, kuwoneka ngati zotupa pakhungu, kuyabwa, matenda am'mimba, matenda ammimba, ndi ena.

Thiazolidinediones ndi mankhwala omwe ali m'gulu latsopano la mankhwala omwe amachepetsa kuchuluka kwa shuga mthupi. Mankhwala osokoneza bongo omwe ali mgululi amachita pamulingo wa receptor. Ma receptor omwe amawona izi amachokera pamaselo amafuta ndi minofu.

Kuchita kwa mankhwala ndi ma receptors kungakulitse chidwi cha maselo kuti apange insulin. Thiazolidinediones imapereka kuchepa kwa insulin kukana, komwe kumakulitsa kwambiri kugwiritsidwa ntchito kwa shuga. Mankhwalawa amaphatikizidwa kwa odwala omwe ali ndi vuto lalikulu la mtima. Kanemayo munkhaniyi apitiliza mutu wa chithandizo cha matenda ashuga.

Zatsopano pa matenda a shuga: matekinoloje, njira, mankhwala

Chaka chilichonse, asayansi padziko lonse lapansi amachita kafukufuku wambiri ndi njira zatsopano zochizira matenda ashuga. Kugwiritsa ntchito mankhwalawa kumangowongolera kuwongolera kwa glucose komanso kupewa zovuta. Komabe, asayansi amapanga njira zatsopano zomwe zimathandizira kuchira.

Choyamba, ndikofunikira kukambirana za zomwe zachitika posachedwa komanso momwe zinthu zasinthira pochiza matenda amtundu woyamba 1:

1. Osati kale kwambiri, sensor yatsopano idawoneka yomwe imayeza glycemia pogwiritsa ntchito laser system. Idapangidwa ndi kampani yotchuka "Net Science". Chipangizocho chimakhazikitsidwa ndi chizindikiro cha fluorescent, chifukwa chomwe chimatha kudziwa kuchuluka kwa shuga mumphindi zochepa zokha. Palibenso chifukwa chobayira chala ndi kutolera magazi kuti aunike.
2. Ndi hypoglycemia, ndichizolowezi kugwiritsa ntchito "Glucagon" yamafuta, yomwe imasungunuka ndi yankho lapadera ndikupaka intramuscularly. Matekinolo amakono akonzanso mankhwalawa omwe amagwira ntchito mwachangu, kuti achepetse kugwiritsa ntchito.
   Izi ndizofunikira kwambiri kwa ana ndi achinyamata, chifukwa "Glucagon" yatsopanoyo ikhoza kugwiritsidwa ntchito kulikonse, ngakhale atakhala pa tebulo. Ili ndiye Glucagon Nasal Powder Nasal Spray, lomwe linapangidwa ndi Locemia Solutions. Horimoni Glucagon imayendetsedwa kudzera m'mphuno, pambuyo pake imalowa mu mucous nembanemba. Mtengo wa chipangizocho siwokwera kwambiri, choncho mankhwalawa amapezeka kwa anthu onse.
3. Medtronic yapanga insulin pampu yatsopano yokhala ndi zabwino zambiri pamitundu yapitayi. Awa ndi ma pump ochokera pa Medtronic Minimed Paradigm mndandanda. Pompo amatha kuyikika m'malo 8 osiyanasiyana, omwe amapereka chitonthozo chapadera kwa wodwala.Imakhala ndi kachitidwe koletsa kutsekeka kwa machubu ndi kudzikongoletsa ndi singano yodziyimira pawokha. Kuphatikiza apo, kuchuluka kwa shuga kumayang'aniridwa mphindi zisanu zilizonse. Pakusintha pang'ono, woipa adzamva chizindikiro. Ngati mugwiritsa ntchito pampu ya Veo, wodwalayo sadzafunika kuyendetsa kayendedwe ka insulin, monga momwe makina ake azichitira izi payekha.

Ntchito yokhala ndi tsinde

Maselo owuma mthupi la munthu amapangidwa kuti azikonza ziwalo zowonongeka ndikupanga matenda a carbohydrate metabolism. Mu shuga mellitus, kuchuluka kwa maselo otere kumatsika kwambiri, chifukwa chomwe zovuta zimayamba, ndikupanga insulin yachilengedwe.

Kuphatikiza apo, chitetezo cha mthupi chimafooka. Chifukwa chake, ndikofunikira kwambiri kulipirira kuchuluka komwe kulibe maselo a tsinde.

Asayansi a Harvard aphunzira kukula maselo olimbitsa thupi a ma cell B mu labotale, chifukwa chomwe insulin imapangidwa moyenera, minofu yowonongeka imabwezeretseka ndipo chitetezo chimalimba.

Kafukufuku wachitika pa mbewa zomwe zimayambitsa matenda ashuga. Chifukwa cha kuyesaku, makoswe adachiritsidwa kwathunthu ku matenda oopsawa. Pakadali pano, chithandizo choterechi chimagwiritsidwa ntchito ku Germany, Israel ndi United States of America.

Chomwe chimapangidwira ndi kupangika kwa maselo a stem ndikuwayambitsanso thupi la odwala matenda ashuga. Maselo amalumikizana ndi minyewa ya kapamba, yomwe imayang'anira insulin, pambuyo pake timadzi timene timapanga.

Chifukwa chake, mlingo ndi kukhazikitsidwa kwa mankhwala a insulin amachepetsa, ndipo mtsogolo nthawi zambiri amathetsedwa.

Kugwiritsa ntchito ma cell a tsinde kumakhala ndi zotsatira zabwino machitidwe onse amthupi. Izi ndizofunikira kwambiri ku zotupa mu impso, ziwalo zoberekera ndi ubongo.

Njira ya Thirani ya Fat Fat

Kafukufuku waposachedwa wa chithandizo chatsopano cha matenda ashuga ndikuwonjezera mafuta kwamafuta. Njirayi imachepetsa kufunika kwa insulini ndikuthandizira kagayidwe kazakudya.

Izi ndichifukwa choti mamolekyulu a glucose adzatengedwa kwambiri ndi ma lipid maselo a mafuta a bulauni. Mafuta awa amapezeka mu nyama zochuluka kwambiri zomwe zimabisala, komanso makanda.

Pazaka zambiri, mafuta amatsika m'magulu ambiri, motero ndikofunikira kuti abwezenso. Zofunikira zimaphatikizira kuchuluka kwa shuga m'magazi ndikuwonjezera njira ya metabolic.

Kuyesera koyamba pothira mafuta minofu ya bulauni kunachitika ku University of Vanderbilt mu mbewa. Zotsatira zake, zidapezeka kuti zoposa theka la zoyeserera zomwe adazipeza zidachotsa matenda ashuga. Pakadali pano, palibe amene adalandira chithandizo ichi.

Katemera wochizira matenda ashuga

Kupanga kwa insulin kumatengera momwe maselo a B alili. Pofuna kupewa kutupika ndi kuletsa kupititsa patsogolo kwa matendawa, ndikofunikira kusintha molekyu ya DNA.

Wasayansi ya Stanford Steinman Lawrence adagwira ntchito imeneyi. Adapanga katemera wobwezeretsanso wotchedwa lawrence steinman.

Imachepetsa chitetezo cha mthupi pamlingo wa DNA, chifukwa chake insulin yokwanira imapangidwa.

Chinsinsi cha katemera ndicholetsa yankho la chitetezo chamthupi. Chifukwa cha zoyesa zaka 2, zidawululidwa kuti ma cell omwe amawononga insulin adachepetsa ntchito yawo. Katemera, palibe zoyipa zomwe zimachitika ndi zovuta zomwe zidadziwika. Katemera sanapangidwire kupewa, koma chithandizo.

Njira yosinthira

Masiku ano, madokotala padziko lonse lapansi akupereka njira yosinthira, chifukwa chake ndizotheka kuchiritsa matenda a shuga 1. Mutha kuyika zinthu izi:

• kapamba, kwathunthu kapena pang'ono,
• maselo a beta
• zilumba za Langerhans,
• gawo la impso
• maselo a tsinde.

Ngakhale zikuwoneka bwino, njirayi ndiyowopsa, ndipo zotsatira zake sizotalika. Chifukwa chake, pambuyo pakuchita opaleshoni, pamakhala ngozi ya zovuta. Anthu odwala matenda ashuga pambuyo pakuchita opaleshoni amatha kuchita popanda insulini kokha kwa zaka 1-2.

Ngati wodwalayo atsimikiza kuchitidwa opaleshoni, ndikofunikira kutsatira zonse zomwe dokotala wamupatsa. Ndikofunikira kwambiri kuti dokotala azikhala ndi chidziwitso chambiri komanso chidziwitso chambiri, popeza chithandizo chosasankhidwa bwino cha postoperative (kotero kuti kulumikizana sikungachotse) kungayambitse zotsatira zoyipa.

Mtundu wachiwiri wa matenda ashuga osadalira insulin, anthu ambiri samayang'ana kwambiri matendawa. Komabe, izi ndizofunikira, popeza mtundu wachiwiri umayamba kukhala woyamba. Ndipo njira zakuchira zimasankhidwa mopitilira muyeso. Masiku ano, pali njira zatsopano zochizira matenda amitundu iwiri.

Kugwiritsa ntchito zida zamagetsi

Chida 1. Zipangizo zatsopano Magnetoturbotron zimaphatikizapo chithandizo kudzera pakukhudzidwa ndi maginito. Mankhwala osokoneza bongo sawachotsa.

Amagwiritsidwa ntchito pa matenda a shuga a 2. Pogwiritsa ntchito chipangizochi, mutha kuchiritsa osati matenda a shuga okha, komanso kuthana ndi mavuto ena ambiri.

Mwachitsanzo, kulimbitsa dongosolo lozungulira, lomwe ndilofunika kwambiri kwa matenda ashuga.

Mkati mwa kukhazikitsa, maginito amapangidwa, omwe amangotuluka nthawi zonse. Izi zimasinthasintha pafupipafupi, liwiro komanso kayendedwe kazungulira. Izi zimapangitsa kuti athe kusintha momwe amayendera kupita ku matenda enaake.

Kuchita izi kumadalira pakupanga minda ya vortex mthupi, yomwe imalowa mkati mwa minofu yakuya kwambiri. Njirayi imatenga mphindi zosachepera 5 pasiti yoyamba. Nthawi yowonjezereka imawonjezeka ndimphindi zochepa. Ingodutsani magawo 15.

Zotsatira zimatha kuchitika pakumwa komanso pambuyo pake kwa mwezi umodzi.

Chida chachiwiri. Kalelo mu 2009, kafukufuku adayamba pa njira yothetsera matenda a shuga. Mpaka pano, zoyesa zambiri zachitika zomwe zapereka zotsatira zabwino. Chifukwa chake, cryosauna imagwiritsidwa ntchito kale ngati mankhwala.

Njirayi imatengera kukhudzana ndi mpweya wa cryogenic wokhala ndi kutentha kochepa. Panthawi yonseyi, wodwalayo amaikidwa mu cryosauna yapadera, pomwe mpweya ndi nayitrogeni zimaperekedwa. Kutentha kumachepa pang'onopang'ono ndipo kumangokhala ndi mphindi ndi theka. Kutalika kwa njirayi ndi 3 maminiti okwanira.

Kuwonetsedwa kotere kuzizira kumayambitsa kuchepetsedwa ndi kukulitsa kwamitsempha yamagazi ndikuwonjezera kugwira ntchito kwa mathero amitsempha, ziwalo zamkati. Izi zimalimbikitsa kukonzanso kwamaselo ndikusinthanso kwa maselo owonongeka.

Pambuyo pa cryotherapy, maselo amthupi amazindikira insulin ngati munthu wathanzi. Izi zimatheka chifukwa chofulumira komanso kukonza njira zonse za metabolic - chakudya, mafuta, michere ndi zina zotero.

Chida chachitatu. Chithandizo cha laser tsopano chikugwiritsidwa ntchito pafupifupi konsekonse. Mankhwalawa amtundu wa matenda a shuga a mtundu wachiwiri, zida zama cellum zimagwiritsidwa ntchito, chifukwa chomwe laser imatumizidwa kumalo osokoneza bongo a kapamba.

Amagwiritsa ntchito ma radiation ya pulsed, infrared, maginito ndi kukoka ndi kuwala kofiira. Kutulutsa kumalowerera mkati mwa zigawo zazing'ono zam'mimba ndi maselo, ndikuwakakamiza kuti azigwira ntchito mwamphamvu. Zotsatira zake, kuchuluka kwa insulin kumachulukanso. Zotsatira zake, mankhwala ochepetsa shuga amachepetsa.

Monotherapy

Posachedwa, asayansi akukonda kwambiri malingaliro akuti kugwiritsa ntchito fiber mu shuga ndikofunikira. Makamaka ngati matendawa akuphatikizidwa ndi kunenepa kwambiri.

Monotherapy nthawi zonse imasonyezedwa kwa kupatsa mphamvu kwa metabolism. Chifukwa chakuti mbewu cellulose imachepetsa kuchuluka kwa glucose omwe amalowetsa m'matumbo, shuga yamagazi imachepetsedwa.

Feature - fiber iyenera kudyedwa pamodzi ndi zovuta zamafuta.

Pazithandizo zina zamatenda a 2 shuga, werengani apa.

Mankhwala atsopano a matenda a shuga 1

1. Lantus SoloStar amatanthauza insulin. Imakamizidwa pang'onopang'ono, zotsatira zake zimatha maola 24. Amapangidwa ndi kampani ya Sanofi-Aventis.

"Humulin NPH" ndi m'badwo watsopano wa insulin. Imalola kuwongolera kwakukulu kwa shuga.

Mankhwala atsopano a matenda a shuga a 2

1. DPP-4 inhibitor (dipeptidyl peptidase-4). Chosakaniza chachikulu chogwira ntchito ndi sitagliptin. Amatsitsa shuga m'magazi pokhapokha pamimba yopanda kanthu, ndiye kuti m'mimba muli ndi njala. Woimira wotchuka ndiye mankhwalawo Januvia. Zotsatira zimatha tsiku. Amaloledwa kugwiritsa ntchito kunenepa kwambiri nthawi iliyonse.

Chowonjezerapo ndikuchepetsa hemoglobin wa glycated ndipo mkhalidwe ndi magwiridwe antchito amaselo amapezeka bwino. GLP-1 inhibitor (glucagon-polypeptide). Kuchita izi kumadalira pakupanga insulini, yomwe imachepetsa shuga ya magazi ndikuletsa kukula kwa glucagon, komwe kumalepheretsa insulini kuti isungunuke shuga.

Chachilendo cha gululi ndikuti hypoglycemia siinayambike, popeza pambuyo pokhazikika pakukhazikika kwa magazi m'magazi, mankhwalawa amaleka kuchitapo kanthu (kuchepetsa kwambiri shuga). Itha kumwa mankhwala onenepa kwambiri komanso mankhwala ena. Zotsalira zake ndi jakisoni wa GLP-1 receptor agonists ndi insulin. Mwa mankhwala odziwika amatha kudziwika Galvus ndi Onglizu.

GLP-1 receptor agonists zimakhudzana ndi mahomoni omwe amawonetsa ma cell a pancreatic okhudza kufunika kopanga insulin. Kukonzekera kumapangitsanso maselo owonongeka a B ndikuchepetsa kumverera kwanjala, chifukwa chake amalimbikitsidwa kuti azinenepa kwambiri.

Kuti mankhwalawa azikhala nthawi yayitali, ndikosayenera kudya chakudya kwa maola angapo, chifukwa chakudya chimawononga zinthu zomwe zimagwira. M'malo agonists m'malo mwamankhwala.: "Baeta" ndi Victoza.Alpha Glucosidase Inhibitorss. Chochitikacho chikufuna kupewa kutembenuka kwa chakudya kukhala shuga.

Pachifukwa ichi, mankhwala amatengedwa mukatha kudya. Ndi zoletsedwa kugwiritsa ntchito limodzi ndi mankhwala "Metformin". Mankhwala otchuka: Diastabol ndi Glucobay.

Anthu ambiri amakayikira njira zatsopano zoperekera matenda ashuga ndi mankhwala obwera kumene.

Komabe, lingaliroli ndi lolakwika, chifukwa asayansi padziko lonse lapansi akuyesera kupeza njira yabwino komanso yothandiza kwambiri yothetsera matenda ashuga. Kuphatikiza apo, njira zonse ndi mankhwalawa zimayendetsedwa kubwezeretsa maselo a beta ndikupanga insulin yawo yomwe.

Chithandizo chatsopano cha matenda a shuga a 2

Mellitus wosadalira shuga wa insulin ndimatenda a autoimmune omwe amadziwika chifukwa chopezeka m'matumbo a glucose, ndikudziunjikira kwake m'magazi.

Njira zatsopano zochizira matenda amisala otchedwa II mellitus sizingangokulitsa vuto la wodwalayo, komanso kuti zithetse zomwe zimayambitsa matendawa.

Momwe shuga imathandizidwira

Matenda a shuga amayesedwa ndi mitundu iwiri ya njira ya pathological:

• Mtundu 1 - wodalira insulini: chomwe chimayambitsa matendawa ndikuphwanya kupanga kwa insulini (izi zimakonda kuphatikizidwa ndi kutengera kwa chibadwa komanso mantha akulu).
• Mtundu 2 ndi insulin-Independent: chifukwa chachikulu sichinakhazikitsidwe, koma pali zinthu zingapo zomwe zimayambitsa chitukuko cha matendawa (kunenepa kwambiri, moyo wamunthu, matenda oopsa).

Chizindikiro chachikulu cha matenda ashuga ndi hyperglycemia (kuchuluka kwa ndende yamagazi). Chifukwa cha kuchepa kwa insulin kapena kuthekera kwake "kuchepetsa" shuga omwe adalandira kuchokera ku chakudya, glucose samagawidwa m'thupi lonse, koma amakhazikika m'mitsempha yamagazi.

Matenda a shuga amayambitsa matenda ambiri:

• kulephera kwa mtima
• mafuta amchiwindi,
• kuphwanya kwamikodzo,
• encephalopathy
• kutayika kwamaso
• kapamba,
• zigawenga.

Popewa matenda oterewa, mankhwala ovuta anapangidwa.

Chithandizo kapena chizolowezi cha matenda ashuga chimagwiritsidwa ntchito ndimankhwala omwe amachepetsa shuga, magazi ndi zakudya zochepa (tebulo No. 5) komanso masewera olimbitsa thupi.

Mtundu woyamba wa shuga, chithandizo chachikulu ndicho insulinane insulin. Uwu ndi mtundu wothandizira kwa kapamba kuti apange mahomoni ofanana ndi insulin. Kuchiza kumatenga zaka zambiri, nthawi zakhululukidwa zamitundu ina yosagwiritsa ntchito insulin zimayenderana ndi kutsatira kwambiri zakudya zamagulu ochepa.

Matenda a Type 1, pankhani ya 2, sakhala wamba, koma chithandizo chambiri ndizovuta kwambiri.

Chiwerengero cha anthu omwe ali ndi hyperglycemia chikuwonjezeka chaka chilichonse, zomwe zimapangitsa madokotala ndi asayansi kuyang'ana njira zabwino zopewera matenda am'mimba. Njira zatsopano zikupangika zomwe zimalepheretsa chitukuko cha matendawa.

Hyperglycemia chigamba

Njira iyi yolamulira glucose wamkulu ndiyodziwika pakati pa ogwiritsa ntchito intaneti. Chigamba chodzaza ndi njira yapadera ya mahomoni ndipo si njira yolimbana ndi matenda ashuga, koma njira yodzitetezera.

Malinga ndi ndemanga, chigambachi chimalimbikitsa kutentha kwa minofu ya subcutaneous adipose, yomwe imasokoneza kapamba. Lingaliroli ndi la otukula achi China.

Mankhwala

Zochitika zaposachedwa zamankhwala zapangitsa kuti zitheke kupeza mankhwala osagwirizana ndi glucose yowonjezereka komanso kugawa kwake mokakamizidwa. Mankhwalawa amaphatikiza pioglitazones ndi rosiglitazones. Zotsatira zazikulu zamankhwala: kuyamwa kwa insulin receptors kuti magazi a shuga asakhazikika.

Njira zodziwika bwino zotere ndi:

Mlingo wambiri patsiku soposa 45 mg, ndipo wamba ndi 30 mg. Kulandila kumachitika kamodzi.

Zoyipa zotsutsana ndi:

• mimba
• njira yodalira matenda a insulin,
• pachimake chiwindi kulephera
• zaka zosakwana 18.

Mankhwala samatengera insulin, amangoyambitsa kapangidwe kake. Zotsatira zoyipa sizimalamulidwa motsutsana ndi maziko a mankhwala antidiabetesic masiku ano.

Kudzipatula

Chinsinsi cha mankhwalawa: kuwonongedwa kwamafuta acid ndi shuga mwakukulitsa mphamvu za mitochondrial. Pofuna kuwotcha zowonjezera, kukonzekera komwe kumapangidwa kovomerezedwa ndi All-Russian Health Organisation kumagwiritsidwa ntchito. Kuchepa mafuta kumachitika mwachangu.

Kumwa mankhwala osinthika kumakupatsani mwayi wowotcha ma calorie, onetsetsani kuti akuwonda, omwe amayamba kupanga popanga mahomoni achifrenchi.

Cell mankhwala

Njira yatsopano ya endocrinology. Ku Russia, kuvomerezedwa kwa chithandizo ngati ichi cha matenda ashuga sikunalandiridwe, koma njirayi yakhala ikuchitika kwa nthawi yayitali kunja. Njira yolimbana ndi tsinde sikuti ikungolimbikitsa kukonzekera kwa insulin, komanso kuti athetse ma pathologies mu kapamba.

Pochiza matenda a shuga kunyumba, akatswiri akulangizani DiaLife. Ichi ndi chida chapadera:

• Amasinthasintha shuga
• Amayang'anira ntchito ya pancreatic
• Chotsani puffness, limayendetsa madzi kagayidwe
• Amawongolera masomphenya
• Zoyenera akulu ndi ana.
• Alibe zotsutsana

Opanga alandila ziphaso zonse zofunika ndi ziphaso za mbiri ku Russia komanso m'maiko oyandikana.

Timapereka kuchotsera kwa owerenga tsamba lathu!

Gulani pa tsamba lovomerezeka

Maselo a stem ndi othandizira padziko lonse lapansi pobwezeretsa chiwalo kapena kachitidwe komwe kanataya ntchito zake zofunika. Therapy ikuchitika mu magawo angapo:

1. Kufunafuna chithandizo chamankhwala ndi kutolera zakuthupi.
2. Kukonzekera kwa zinthu zomwe zatulutsidwa: kafukufuku wa zasayansi, kubereka.
3. Kuphatikizika kwa cell (chobadwa, koma ndi genome yoyambitsa, ndi maselo atsopano a tsinde kuti tisinthike).

Njirayi imayendetsedwa ndi chiwopsezo chochepa, izi zimagwirizanitsidwa ndi mawonekedwe a thupi la wodwalayo

Kugwiritsa ntchito ulusi si njira yatsopano yolimbana ndi matenda ashuga, monga chithandizo chothandizira. Kugwiritsa ntchito CHIKWANGWANI kumakhudza kukwezedwa kwa kagayidwe kazakudya, pomwe glucose amatengeka, zinthu zowola ndi poizoni zimachotsedwa m'matumbo, kulemera kumakhala kwachilendo ndipo kuthamanga kwamadzi kumachitika. Cellulose ilipo mu CHIKWANGWANI.

Chithandizo chachikhalidwe kapena njira zatsopano?

Kusankha kwa chithandizo kuyenera kuperekedwa kwa katswiri. Endocrinologists amalangiza musanagwiritse ntchito njira zamakedzana komanso zamakono zamankhwala - kukayezetsa mokwanira, kuzindikira chomwe chimayambitsa matenda, kenako kuthana nawo.

Chithandizo chamankhwala a mtundu wa shuga wachiwiri ndi motere:

• kusintha kwa zakudya ndi kuyambitsa zochitika zolimbitsa thupi,
• mankhwala hypoglycemic mankhwala,
• mankhwala a insulin.

Kuchiza ndi njira zachikhalidwe kumagwiritsidwa ntchito kwanthawi yayitali. Kuphatikizidwa kwa mankhwala kumaphatikizapo metformin mu mawonekedwe a hydrochloride. Zotsatira zakuchizira zimachitika chifukwa chakuchepa kwa kuchuluka kwa shuga mu seramu ndi plasma, pomwe metformin sikukhudza insulini.

Cholinga chachikulu cha othandizira a hypoglycemic ndikukhazikitsa shuga yovomerezeka. Kupititsa patsogolo mkhalidwe wa kapamba, ma decoctions ochokera ku mankhwala azamankhwala amatengedwa, komanso mankhwala a enzyme.

Poyerekeza ndi matekinoloje atsopano ndi mankhwala osokoneza bongo, njira zachikhalidwe sizothandiza chifukwa zimafunanso kubwereza kwakanthawi pochiza matenda ashuga. Komabe, nthawi zambiri, chithandizo chamankhwala amagwiritsidwabe ntchito.

Ubwino wa njira zatsopano ndikuchotsa matendawa kwa nthawi yayitali. Odwala ena omwe amalandila chithandizo cha tsinde adazindikira kuti akusowa shuga kwa zaka zingapo, komabe, amatsatira zakudya zomwe amalimbikitsidwa ndipo nthawi zonse amakhala akuchita masewera olimbitsa thupi.

Sikuti njira zamakono zonse zomwe zimagwiritsidwa ntchito ku Russian Federation, zina mwazomwezi, monga chithandizo cha ma cell, sizikuchitika mdzikolo. Njira zina zitha kukhala zopanda phindu pakukhazikitsa njira yodalira matenda a shuga. Zoyipa zake ndizochulukirachulukira, zosafikirika nzika wamba.

Kupewa ndi malingaliro

Njira zodzitetezera zimaphatikizapo kudya komanso kuthandiza zolimbitsa thupi zofunika. Type 2 shuga mellitus amapezeka mwa anthu apakati komanso achikulire. Gulu la nzika zolimbitsa thupi ndi zakudya zapadera zomwe zimakhala ndi chakudya chochepa kwambiri zimapangidwira gulu ili la nzika.

Komanso, pofuna kupewa, kugwiritsa ntchito mankhwala osokoneza bongo ndi mankhwala a zitsamba.

Akatswiri amalimbikitsa kuti asadzipangire okha, koma kupatsa thanzi lawo akatswiri odziwa bwino ntchito za endocrinology. Amathandizira chithandizo chothandiza kwambiri.

Matenda a shuga nthawi zonse amayambitsa zovuta zakupha. Mwazi wamagazi ochulukirapo ndi woopsa kwambiri.

Lyudmila Antonova mu Disembala 2018 adafotokoza mwatsatanetsatane za chithandizo cha matenda ashuga. Werengani kwathunthu

Zatsopano komanso zothandiza mankhwalawa amtundu wa shuga

Matenda a shuga ndivuto lalikulu kwa onse azachipatala ndi m'chitaganya. Chiwerengero cha milandu chikukula, china chatsopano chikufunika pochiza matenda a shuga 2 mellitus (pano - T2DM), othandiza kwambiri. Matenda amtunduwu amagwirizanitsidwa ndi kuwonongeka kwa insulin receptors, yomwe imayambitsa kusokonekera kwa mapangidwe a pancreatic b ndipo ndiye chizindikiro chachikulu cha matendawa. Koma akatswiri akukhulupirira kuti kusokonekera kwa ma islet b cell amenewa kumatha kusintha.

Ngakhale kuti chithandizo cha matendawa chimasankhidwa payekhapayekha kwa wodwala aliyense, chifukwa cha njira zachipatala ndikudya komanso zolimbitsa thupi, zotheka. Chimodzi mwazinthu zofunikira zomwe zikuyang'aniridwa ndi chithandizo cha T2DM ndikuchepetsa zowopsa za mawonekedwe ndi chitukuko cha matenda amtima, kuti muchepetse zotsatira za kuwonongeka kwa insulin receptors.

Chikhalidwe chokhazikitsidwa pothandizidwa ndi matendawa ndikufuna kuthana ndi zomwe zikubwera. Nthawi zambiri, wodwala amayamba kuthandizidwa ndimankhwala othandizira. Ngati sizikuyenda bwino, ndiye kuti amapereka mankhwala amodzi omwe amachepetsa shuga ndikupitiliza kuwunikira, akuyembekeza kuti akwaniritse chipepeso chokhazikika cha kagayidwe kazachilengedwe. Ngati izi sizingachitike, ndiye kuti pali njira ziwiri: kuchuluka kwa mankhwala omwe amachepetsa shuga omwe wodwala akutenga kale, kapena kuphatikiza mitundu ingapo ya mankhwalawa. Chithandizo chotere chimakhala kwa miyezi ingapo mpaka zaka zingapo.

Koma kuchedwetsa chithandizo pakanthawi kochepa kumadzichitira zokha. Chifukwa chake, makampani apadziko lonse lapansi adapanga osati mankhwala atsopano omwe awonetsedwa kuti ndi othandiza, komanso njira zamakono zochizira T2DM, ndi njira zina zakwaniritsire zolinga za shuga zamagazi, zomwe zimathandiza bwino odwala omwe ali kumapeto kwa matendawa. Kuvomerezedwa kunafikiridwa pa chithandizo cha hyperglycemia mu T2DM.

Njira yotsogola yogwiritsira ntchito shuga yotsitsa shuga sikuti ndiyophweka chabe, kugwiritsa ntchito sikuti kumayendetsedwa ndi kugwiritsa ntchito mankhwala amakono, amakono. Makhalidwe enieni adapezeka a glycated hemoglobin, omwe ndi ochepera 7%. Kuisunga pakadali pano kumathandizira kupewa kupewa mavuto a mtima komanso zamitsempha.

Otsutsa amakhulupirira kuti njira imeneyi sichinthu chatsopano, chifukwa mankhwalawa njira, njira ndi njira zotchuka, ndi kuphatikiza kwake kumagwiritsidwa ntchito. Koma izi ndi zoyambira, chifukwa njira yothandizira odwala pakokha ndiyatsopano. Zimakhazikitsidwa poti nthawi yomweyo atazindikira kuti T2DM yakhazikitsidwa, posachedwa, mulingo wabwinobwino wamagazi umafikiridwa, ndipo glycemia imakhazikitsidwa ngati ili yabwinobwino kapena kuwonetsa zizindikiro zomwe zili pafupi nayo. Malinga ndi maphunziro atsopano azachipatala, shuga amathandizidwa m'magawo atatu.

Gawo loyamba - Sinthani miyoyo ndikugwiritsa ntchito metformin

Pakadali pano, kufanana kwa njira yatsopano yothandizirana ndi njira zamakhwala kumadabwitsa. Koma chowonadi ndichakuti madotolo omwe amalimbikitsa kudya, kusintha kwa moyo, masinthidwe azolimbitsa thupi tsiku ndi tsiku amanyalanyaza kuti ndizovuta kwambiri kuchita izi. Kusintha zizolowezi zakale, zakudya, zomwe wodwalayo adazitsatira kwazaka zambiri, kuyang'ana kwambiri kudziletsa kwa ambiri ndizoposa mphamvu. Izi zimatsogolera ku chidziwitso kuti machiritso mwina samachitika, kapena amapita patsogolo pang'onopang'ono.

Nthawi zambiri, madokotala amangokhulupirira kuti wodwalayo akufuna kutsatira malingaliro onse omwe aperekedwa. Komanso ndizowona kuti chakudya chomwe wodwala amayenera kusiya chimamupangitsa kukhala wodalira "narcotic". Ichi ndi chifukwa chachikulu choganizira kuti odwala sakutsatira malangizo a chipatala.

Ndi njira yatsopanoyi, izi zimayang'aniridwa. Chifukwa chake, wodwalayo akangopeza ndi T2DM, amamuika mankhwala monga metformin, poganizira zongowonongera.

Kuti athetse zotsatirapo zake zoyipa, njira yogwiritsira ntchito mankhwalawa imagwiritsidwa ntchito, momwe wodwalayo amawonjezera pang'onopang'ono mlingo wa mankhwalawa pakapita miyezi ingapo, ndikubweretsa gawo labwino kwambiri. Mlingo wotsika wa mankhwala omwe mankhwalawa amayambitsidwa ndi 500 mg.Amatengedwa nthawi 1-2 tsiku lonse ndi chakudya, nthawi zambiri pa kadzutsa ndi chakudya chamadzulo.

Wodwala amatha kudwala matenda am'mimba mkati mwa sabata limodzi. Ngati sichoncho, ndiye kuti kuchuluka kwa mankhwalawo omwe amwedwa kumawonjezereka ndi 50-100%, ndipo kudya kumapangidwa nthawi ya chakudya.

Koma mu vuto ili, pakhoza kukhala zovuta ndi chiwindi ndi kapamba. Kenako, kumwa mankhwalawo kumachepetsedwa ku mlingo wapitayo ndikuwonjezera pambuyo pake.

Kukhazikika kuti, kutenga 850 mg ya mankhwalawa kawiri pa tsiku, wodwalayo amalandira chithandizo chambiri.

Gawo lachiwiri la chithandizo ndikugwiritsa ntchito mankhwala ochepetsa shuga

Pachigawo choyamba, magazi a wodwalayo amatha kukhala bwinobwino. Koma ngati izi sizikuthandizani, pitani gawo lachiwiri, momwe mumagwiritsidwa ntchito mankhwala ochepetsa shuga, kuphatikiza. Izi zimachitika kuti zithandizire insulini komanso kuchepetsa insulin. Palibe malingaliro aliwonse kwa odwala onse pankhaniyi; mankhwalawa amasankhidwa ndikuphatikizidwa mosiyanasiyana kwa wodwala aliyense.

Chowonadi ndi chakuti mankhwalawa amaphatikizidwa poganizira kuti aliyense wa iwo ali ndi njira yosiyana yogwiritsira ntchito thupi. Mankhwala monga insulin, glitazone, sulfonylureas amaphatikizidwa ndi metformin, omwe amagwira ntchito mokwanira kuti awonjezere mphamvu ya insulin, koma zotsatira zake zimayendetsedwa kumankhwala osiyanasiyana amkati.

Ngati pazigawo ziwiri zoyambirira sizinatheke kukwaniritsa glycemia wabwinobwino, ndiye kuti amayamba kuwonjezera kapena kuwonjezera insulin, kapena kuwonjezera wina, mankhwala ochepetsa shuga wachitatu. Dokotala amayenera kupaka kugwiritsa ntchito mita, ndikufotokozera, nthawi ndi kangati momwe angagwiritsire ntchito kuyeza. Mankhwala wachitatu amawonetsedwa ngati mendulo ya glycated hemoglobin ili pansipa 8%.

Mankhwala a insulini, nthawi yayitali insulin imagwiritsidwa ntchito, yomwe imaperekedwa kwa wodwala asanagone. Mlingo wa mankhwalawa umachulukitsidwa pafupipafupi mpaka shuga m'magazi akafika pamwambo. Glycated hemoglobin imayesedwa pakatha miyezi ingapo. Matenda a wodwalayo angafunikire kuti adokotala awonjezere insulin.

Mwa mankhwala omwe ali ndi vuto la hypoglycemic ndipo amatha kuwonjezeredwa ngati lachitatu, pakhoza kukhala izi:

• alpha glycosidase zoletsa - amakhala ndi kuchepetsa shuga wotsika,
• ma glinids ndiokwera mtengo kwambiri
• pramlintide ndi exenatide - zochitika zazing'ono zamankhwala pakugwiritsa ntchito kwawo.

Chifukwa chake, njira yatsopano yoperekera chithandizo cha T2DM ili ndi zosiyana zingapo. Choyamba, pamayambiriro a mankhwalawa, matendawo akangopezeka, mankhwalawa amagwiritsidwa ntchito, omwe amagwiritsidwa ntchito limodzi ndi zakudya zoyenera komanso zolimbitsa thupi zolimbitsa thupi.

Kachiwiri, zizindikiro zenizeni za hemoglobin ya glycated, zomwe ndizochepera 7%, zimawerengedwa. Chachitatu, gawo lirilonse la chithandizo limakwaniritsa zolinga zenizeni, zomwe zikufotokozedwa zenizeni. Ngati sizikwaniritsidwa, pitani patsogolo.

Kuphatikiza apo, njira yatsopanoyi imapereka chida chofulumira kwambiri komanso kuwonjezera kwa mankhwala omwe amachepetsa shuga. Ngati palibe zoyembekezeredwa zochizira, chithandizo cha insulin kwambiri chimagwiritsidwa ntchito nthawi yomweyo. Kwa chithandizo chachikhalidwe, kugwiritsa ntchito kwake pamlingowu kumawerengedwa mwachangu. Kugwiritsa ntchito kudziyang'anira pawokha ndi gawo la njira yatsopano.

Mankhwala a T2DM, kugwiritsa ntchito bwino kumatengera njira yophatikizika yomwe imakhudzanso matendawa.

Kuchiza kumayikidwa kokha ndi dokotala yemwe amayang'ana wodwalayo panthawi yonse yochira.

Mankhwala amtundu uliwonse wa matenda ovuta ngati amenewo samaperekedwa.

Njira zatsopano zochizira matenda amishuga 2 zimaphatikizira magnetotherapy, chithandizo ndi glitazones ndi incretinomimetics, komanso kugwiritsa ntchito maselo amtsinde. Mankhwalawa sakhala ndi poizoni komanso amachepetsa thupi.

Nthawi zambiri mtundu wachiwiri wa shuga umadziwika ndi anthu achikulire. Nthawi zambiri, zimachitika motsutsana ndi maziko a kupsinjika kosalekeza. Ziwalo zam'mimba zimasilira kwambiri insulin, yomwe imanyamula shuga ndipo imathandizira kulowa kwake m'magazi. Thupi limachulukitsa kupangika kwa timadzi timeneti, koma kuchuluka kwa shuga m'magazi kumakulirabe, ndipo chifukwa chake, kubayidwa kwa insulin ndikofunikira.

Tsoka ilo, masiku ano, achinyamata ochulukirachulukira ali ndi matenda amtunduwu. Mwinanso, izi zimatheka ndi kufulumira kwa moyo, kupsinjika kwamphamvu kwamaganizidwe, kugwira ntchito mopitirira muyeso. Anthu samakhala achimwemwe kuchokera ku moyo kapena kuntchito, zomwe zimapangitsa kukhala ndi zofunikira kwambiri pakukula kwa matendawa.

Zomwe zimayambitsa matenda a shuga a 2 ndi:

• nkhawa, kuda nkhawa,
• kunenepa
• zizolowezi zoipa
• chakudya cholakwika
• matenda amtima.

Mosiyana ndi matenda amtundu wa 1 shuga, omwe amadziwika kwambiri mwa ana ndi achinyamata, matenda a shuga a 2 samadalira insulin.

Matendawa amawonekera mu zotsatirazi zosasangalatsa:

• ludzu losalekeza komanso pakamwa louma
• dzanzi pang'ono miyendo ndi mikono, m'malo osasamala, zilonda zam'mimba ndizotheka,
• kuwonongeka kwamawonekedwe
• Kuuma ndi kuwonongeka kwa khungu,
• kutopa ndi kufooka kosalekeza,
• mavuto ndi kusowa kwa chakudya ndi chimbudzi.

Ngati zizindikiro zingapo zapezeka, iyi ndi nthawi yoyenera kuchezera dokotala. Mukangoyamba chithandizo cha matenda, nthawi zambiri zimakhala zofooketsa zotsatira zake zoipa m'thupi kapena kuchira.

Matenda a shuga ndi matenda osachiritsika, koma njira yake imatha kutha ndipo mavuto obwera chifukwa cha matenda ashuga amachotsedwa. Njira zakuchira zitha kugawidwa m'magulu awiri akuluakulu.

Izi ndi njira zoyeserera nthawi yomwe zatsimikiza kugwira ntchito kwawo.

Iyi ndi imodzi mwanjira zabwino kwambiri zochiritsira, zomwe, mwatsoka, odwala ambiri omwe ali ndi matenda ashuga sangathe kupirira chopitilira chaka. Njirayi imaphatikizapo:

• kudya kangapo patsiku ndi pang'ono pang'onopang'ono,
• Zakudya za tsiku ndi tsiku siziyenera kupitirira 1500-1800 kcal patsiku,
• sinthani zopangidwa ndi shuga ndi shuga zomwe zimakhala ndi zotsika pang'ono za carb,
• chepetsa mchere wambiri mpaka 4 g patsiku,
• phatikizani masamba ndi zipatso zambiri pazakudya zanu,
• kupatula kumwa mowa.

Nthawi zambiri matenda amtundu wa 2 amakhudza anthu omwe amalemera kwambiri. Gawo losankhidwa mwamankhwala olimbitsa thupi limachepetsa kwambiri kunenepa, limadzaza thupi ndi mpweya. Ndi matenda awa, kuthamanga, kusambira, ndi masewera olimbitsa thupi adzapindula (yogwira bwino ntchito pamenepa).

Dziwani kuti panthawi ya chithandizo, zovuta za masewera olimbitsa thupi ziyenera kusankhidwa malinga ndi zaka, thanzi komanso kuthekera kwa wodwala. Kupanda kutero, mutha kungokulitsa zinthu.

Mosakayikira, matenda onse amachokera ku mitsempha. Thupi lathu silitha kukhala bwino bwino, ndipo tsiku lina limayamba kugwira ntchito molakwika ndi matenda ena ake. Chifukwa chake, muyenera kuyesetsa kuti musakhale amantha kwambiri osatinso kugwira ntchito mopambanitsa. Tiyenera kukumbukira kuti palibe chinthu china chofunikira kuposa thanzi. Zikatero, ma decoctions ochokera ku zitsamba zoziziritsa kukhosi, kuchotsa kwa valerian kungathandize.

Muyeneranso kuyesetsa kuti musalumikizane ndi anthu omwe amachititsa kuti musamayanjane. Ngati izi sizingatheke, ndiye kuti simuyenera kuzimvetsa kwambiri. Maphunziro apadera a auto, omwe amakukhazikitsani munjira yabwino komanso amakulolani kuti muchotse mphamvu zoyipa, atha kukhala othandiza.

Mankhwala omwe amadziwika kwambiri pochiza matenda a shuga ndi otere.

Zimawoneka bwino mankhwalawa matenda a shuga a 2, kuphatikizapo mankhwala othandizira pakudya ndi zolimbitsa thupi. Popeza pa gawo loyamba, njira ya kagayidwe kachakudya mthupi imapang'onopang'ono.

Metformin imachepetsa kuyamwa kwa shuga m'magazi. Mankhwalawa asanafike, Biguanide adagwiritsidwa ntchito kumayambiriro kwa zaka za zana la 20, koma osati kale kwambiri komwe adasiyidwa chifukwa anali ndi zotsatira zolimba pamatumbo. Odwala adadandaula za mseru, kusanza, kutsegula m'mimba, kufooka, komanso kuchepa kwa chakudya.

Metmorphine amatsitsa shuga, pafupifupi osavulaza panthawi ya chithandizo. Pa gawo loyambirira la kuyang'anira, mseru pang'ono ndi chizungulire zitha kuchitika, koma posakhalitsa zimadutsa. Iyenera kutengedwa, ndikuwonjezera pang'onopang'ono mlingo, malingana ndi chiwembu chopangidwa ndi adokotala.

Zina mwazotsatira zabwino za Metformin ndi:

• Kuchepetsa chiopsezo cha magazi m'chiwiya,
• amachepetsa magazi m'thupi,
• siziyambitsa kulemera,
• sizoyambitsa hypoglycemia.

Imalimbikitsa kupanga insulin ndi kapamba. Chimapangitsa cell membrane kukhala tcheru kwambiri poyankha insulin. Tengani, monga Metformin, ayenera kuonjezera mlingo. Ndikakhala ndi shuga wambiri magazi, mutha kuyamba kumwa mankhwala akuluakulu. Mankhwalawa ndiwotsika mtengo ndipo amathandizira pochiza matendawa kuti achotse msanga msanga.

Ili ndi zovuta zambiri:

• Khungu
• poizoni ku chiwindi ndi impso
• achina,
• zovuta zam'mimba
• kunenepa

Awa ndimankhwala omwe amapangidwira kuti akalimbikitse kwambiri kupanga insulin ndikuwonjezera chidwi cha maselo ku timadzi timeneti. Amathandizira kutsika kwamphamvu kwa glucose wamagazi, koma amayambitsa mavuto pakupanga madzi am'mimba, njira yogaya, amalimbikitsa hypoglycemia ndipo ndi okwera mtengo.

Chimodzi mwazachipatala chodziwika bwino cha matenda a shuga a 2. Ndiotsika mtengo, imasintha kagayidwe ka lipid m'thupi.

Zina zoyipa zochizira matenda a shuga ndizofunikira kuwunika pafupipafupi kuchuluka kwa shuga, jakisoni. Insulin ingayambitsenso kulemera kwakukulu ndi hypoglycemia.

Kusokonezeka kwa mitsempha ndi kupsinjika ndiye gwero lalikulu la matenda ashuga a 2. Tikakhala ndi mantha, mahomoni monga thyroxine ndi adrenaline amapangidwa mthupi lalikulu. Amakonzedwa ndikuwotchedwa mothandizidwa ndi okosijeni, chifukwa chake, ndalama zake zazikulu ndizofunikira, zimaperekedwa ndi masewera.

Koma nthawi zonse pamakhala mwayi komanso nthawi yopuma yochitira masewera olimbitsa thupi. Poterepa, chipangizo chapadera chomwe chimagwiritsa ntchito maginito ndikuyambitsa ntchito ya ziwalo zonse zamthupi zithandizira.

Mankhwala a Laser ndi cryosauna amagwiranso ntchito mfundo zomwezi. Physiotherapy yamtunduwu pochiza matenda a shuga sangathe kugwiritsidwa ntchito:

• matenda oncological
• kutentha kwambiri
• chifuwa chachikulu
• hypotension
• kutopa
• mimba.

Glitazones ndi mankhwala apadera omwe amalimbikitsa chidwi cha minofu ya thupi kuti ipangire insulin. Ayenera kukhala oledzera ndi chakudya.

Zotsatira zoyipa ndi:

• kutupa
• kunenepa
• mafupa olimba akuwonjezeka
• amachita pang'onopang'ono.

• matenda a chiwindi ndi impso,
• singagwiritsidwe ntchito ndi insulin,
• mimba ndi mkaka wa m`mawere.

Exenatide, Sitagliptin ndi mankhwala a gululi amagwira ntchito bwino limodzi ndi njira zina zochizira matenda amitundu 2 matenda a shuga, mwachitsanzo, zimaphatikizidwa bwino ndi Metformin.

Mfundo za zochita za Exenatide zimayenderana ndi kukondoweza kwa kupanga insulin ndi kapamba. Komanso, mankhwalawa amathandizira kuyang'anira kapangidwe ka madzi am'mimba komanso amachepetsa chimbudzi ndi chakudya, chomwe chimayambitsa kuwonda.

Pa gawo loyamba kumwa mankhwalawa, kunyansidwa pang'ono ndi m'mimba ndizotheka.Zotsatira zoyipa zimaphatikizapo zovuta pa dongosolo logaya chakudya, kufunika kwa jakisoni, ndi chidziwitso chochepa.

Sitagliptin imachita chimodzimodzi ndi Exenatide, ikuthandizira kupanga insulini ndikupereka mphamvu kwambiri pakupanga kwa glucagon. Ili ndi mphamvu yayitali, imachepetsa shuga. Ndikokwanira kumwa kamodzi kokha patsiku. Mankhwalawa ndi okwera mtengo komanso osaphunzira pang'ono. Sizimayambitsa kulemera.

Iyi ndi njira yokwera mtengo kwambiri komanso yodalirika. Koma zimabweretsa zotsatira zodabwitsa, zimapangitsa kuti insulin ipangidwe ndi thupi palokha. Imasinthasintha kagayidwe ndipo imagwira pafupifupi matenda aliwonse a endocrine. Ili ndi njira yatsopano kwambiri yachipatala. Chobweretsera chachikulu ndi kudziwa kwawo kotsika komanso kuthekera kwakukulu kwa zotsatira zoyipa.

Ngati mukunenepa kwambiri, pali abale omwe akudwala matenda amtundu wa 2, ndiye izi zikuwonetsa chiwopsezo chowonjezereka. Popewa matenda, muyenera kuyang'anira thanzi lanu. Nthawi zonse tengani mayeso a shuga, sinthani zakudya ndipo musanyalanyaze zolimbitsa thupi. Pazakudya, ndibwino kuti muzikonda zakudya zakubzala, kupatula lokoma, ufa, mbatata.

Muyenera kumwa madzi ambiri, chifukwa ndi matenda ashuga, ma acid amapangidwa ndikudziunjikira m'thupi, omwe amayamba kukhala ndi vuto lililonse mthupi.

Mellitus wosadalira shuga wa insulin ndimatenda a autoimmune omwe amadziwika chifukwa chopezeka m'matumbo a glucose, ndikudziunjikira kwake m'magazi.

Njira zatsopano zochizira matenda amisala otchedwa II mellitus sizingangokulitsa vuto la wodwalayo, komanso kuti zithetse zomwe zimayambitsa matendawa.

Matenda a shuga amayesedwa ndi mitundu iwiri ya njira ya pathological:

• Mtundu 1 - wodalira insulini: chomwe chimayambitsa matendawa ndikuphwanya kupanga kwa insulini (izi zimakonda kuphatikizidwa ndi kutengera kwa chibadwa komanso mantha akulu).
• Mtundu 2 ndi insulin-Independent: chifukwa chachikulu sichinakhazikitsidwe, koma pali zinthu zingapo zomwe zimayambitsa chitukuko cha matendawa (kunenepa kwambiri, moyo wamunthu, matenda oopsa).

Chizindikiro chachikulu cha matenda ashuga ndi hyperglycemia (kuchuluka kwa ndende yamagazi). Chifukwa cha kuchepa kwa insulin kapena kuthekera kwake "kuchepetsa" shuga omwe adalandira kuchokera ku chakudya, glucose samagawidwa m'thupi lonse, koma amakhazikika m'mitsempha yamagazi.

Matenda a shuga amayambitsa matenda ambiri:

• kulephera kwa mtima
• mafuta amchiwindi,
• kuphwanya kwamikodzo,
• encephalopathy
• kutayika kwamaso
• kapamba,
• zigawenga.

Popewa matenda oterewa, mankhwala ovuta anapangidwa.

Chithandizo kapena chizolowezi cha matenda ashuga chimagwiritsidwa ntchito ndimankhwala omwe amachepetsa shuga, magazi ndi zakudya zochepa (tebulo No. 5) komanso masewera olimbitsa thupi.

Mtundu woyamba wa shuga, chithandizo chachikulu ndicho insulinane insulin. Uwu ndi mtundu wothandizira kwa kapamba kuti apange mahomoni ofanana ndi insulin. Kuchiza kumatenga zaka zambiri, nthawi zakhululukidwa zamitundu ina yosagwiritsa ntchito insulin zimayenderana ndi kutsatira kwambiri zakudya zamagulu ochepa.

Matenda a Type 1, pankhani ya 2, sakhala wamba, koma chithandizo chambiri ndizovuta kwambiri.

Chiwerengero cha anthu omwe ali ndi hyperglycemia chikuwonjezeka chaka chilichonse, zomwe zimapangitsa madokotala ndi asayansi kuyang'ana njira zabwino zopewera matenda am'mimba. Njira zatsopano zikupangika zomwe zimalepheretsa chitukuko cha matendawa.

1. 
   Rosa, Volkova Diabetes mu ma chart ndi magome. Zakudya ndipo osati / Volkova Rosa. - M: AST, 2013 .-- 665 p.
2. 
   Davidenkova E.F., Liberman I.S. Genetics ya matenda a shuga a mellitus, Mankhwala - M., 2012. - 160 p.
3. 
   P.A. Lodewick, D. Biermann, B. Tuchey "Munthu ndi matenda a shuga." M. - St. Petersburg, "Binom", "Nevsky Dialect", 2001
4. Akhmanov M. Matenda a shuga muukalamba.St. Petersburg, yosindikiza nyumba "Nevsky Prospect", 2000-2002, masamba 179, kufalitsidwa konsekonse kwa makope 77,000.
5. N.A.Dolzhenkova “Matenda A shuga. Buku la odwala ndi okondedwa awo. " St. Petersburg, yosindikiza nyumba "Peter", 2000

Ndiloleni ndidziwitse. Dzina langa ndi Elena. Ndakhala ndikugwira ntchito ya endocrinologist kwa zaka zoposa 10. Ndikukhulupirira kuti pakadali pano ndili katswiri pantchito yanga ndipo ndikufuna kuthandiza alendo onse omwe amapezeka patsamba lino kuti athetse zovuta koma osati ntchito. Zinthu zonse za tsambalo amazisonkhanitsa ndikuzikonza mosamala kuti athe kufotokoza zambiri zofunikira. Musanagwiritse ntchito zomwe zikufotokozedwa pa webusaitiyi, kufunsana ndi akatswiri ndizofunikira nthawi zonse.