Metformin yochepetsa thupi: ndemanga za iwo omwe ataya thupi, forum

Iwo adayamba kukambirana za chinthu cha Metformin mu 1922, adafotokoza zomwe adachita makamaka mu 1929, ndipo adayamba kutchuka pambuyo pa 1950. Kuyambira pamenepo, asayansi adayamba kuwonetsa chidwi ndi metformin monga othandizira kuchepetsa shuga zomwe sizikhudza mtima ndi mitsempha yamagazi.

Pambuyo pophunzira mosamala ndikufananiza ndi mankhwala ena a gululi, adayamba kulembedwa mokhazikika ku Canada mu 70s ndi mtundu wa 2 shuga, ndipo ku America idaloledwa kokha mu 1994, pomwe idavomerezedwa ndi FDA.

Kodi Metformin ndi chiyani?

Mwa kapangidwe ka mankhwala, metformin ndiye woimira wamkulu wa Biguanides. Ndi mankhwala a mzere woyamba kuchitira matenda amishuga amtundu wa 2, amadziwika kuti ndiwotchuka kwambiri padziko lonse lapansi. Mosiyana ndi magulu ena a othandizira pakamwa, ndibwino kuti azikhala ndi mphamvu m'malo mwake kapena zimathandizira kuchepetsa. Komanso metformin nthawi zina imagwiritsidwa ntchito ngati munthu amachepetsa thupi (kuchiza kunenepa) mwa anthu opanda matenda a shuga, ngakhale sanapangidwe pachifukwa ichi.

Zokhudza kuchepa kwa thupi zimachitika pamachitidwe angapo:

• mulingo wa cholesterol "yoyipa" yafupika,
• kuyamwa kwa zosavuta zam'matumbo m'mimba zimachepetsedwa,
• mapangidwe a glycogen ndi olepheretsa,
• glucose processing imathandizira kwambiri.

Mankhwala

Mankhwalawa ndi mndandanda wamitundu yayikulu. Kupadera kwake ndikuti samakulitsa kapangidwe ka insulin yake. Kuphatikiza apo, sizikhudza kuchuluka kwa glucose mwa anthu athanzi. Metformin imatha kukulitsa chidwi cha insulini ya ma receptors apadera, imalepheretsa kuyamwa kwa glucose m'matumbo am'mimba ndikuchepetsa kuchuluka kwake m'magazi poletsa kutembenuka kwa chiwindi.

Kuphatikiza apo, metformin imakhudzanso kagayidwe kamafuta: imatsitsa cholesterol, otsika osalimba lipoprotein ndi triglycerides, ndipo nthawi yomweyo imawonjezera zomwe zili pazachulukitsa lipoproteins. Panthawi yamankhwala, kulemera kwa thupi kumakhalabe kosasinthika (komwe kumakhalanso zotsatira zabwino), kapena kuchepa pang'onopang'ono.

Kuphatikiza kwakukulu kwazinthu kumatheka pafupifupi maola 2.5 mutatha kugwiritsa ntchito. Hafu ya moyo ndi pafupifupi maola 7. Ngati aimpso ntchito, chiwopsezo cha kudzikundikira m'thupi zimachulukanso, zomwe zimadzaza ndi zovuta.

Zizindikiro ndi contraindication

Metformin imalembedwa mtundu wa odwala matenda ashuga a 2 omwe amayamba kunenepa kwambiri pomwe kusintha kwa zakudya komanso kukhalapo kwa masewera sizinabweretse zotsatira zomwe zikuyembekezeka. Itha kugwiritsidwa ntchito ngati mankhwala okhawo osagwirizana ndi matenda a shuga kwa ana azaka 10 ndi akulu, kapena monga mankhwala osokoneza bongo. Akuluakulu amathanso kuphatikiza ndi mapiritsi ena a hypoglycemic.

Mankhwala ali ndi zotsutsana zambiri:

• Thupi lawo ndi chinthu china chilichonse.
• Simungathe kuidya panthawi yokhwima ngati chakudya chochepa kuposa 1000 kcal chimadyedwa patsiku.
• Mimba
• Kulephera kwamtima kwambiri, kuphwanya kwam'mimba kovuta, kupuma pamavuto.
• Matenda aimpso. Izi zimaphatikizanso kusokonezeka kwa kuchuluka kwa madzi, kugwedezeka, matenda opatsirana omwe angayambitse kulephera kwa impso.
• Zowonjezera zazikulu za opaleshoni ndikuvulala.
• Matenda a shuga ketoacidosis, precoma ndi chikomokere.
• Kuphwanya chiwindi, uchidakwa, poyizoni wazakumwa ndi zakumwa zoledzeretsa.
• Kudzikundikira kwa lactic acid mu chigoba minofu, khungu ndi ubongo, zomwe zimatchedwa lactic acidosis.

Metformin sayenera kumwedwa ndi anthu okalamba omwe amakhala ndi zolemera zolimbitsa thupi - izi zimachitika chifukwa cha kupezeka kwa lactic acidosis. Amayi omwe akuyamwitsa amayeneranso kusamala ndikumwa mankhwalawo pokhapokha ngati adagwirizana ndi adokotala, koma nthawi zambiri amamaliza kuyamwa kuti asavulaze mwana.

Momwe mungatenge metformin

Nthawi zambiri zimayambitsa zotsatira zosakhudzidwa kuchokera m'matumbo am'mimba, kusintha kulolerana, tikulimbikitsidwa kuti mukulitse mlingo pang'onopang'ono ndikuwaphwanya.

Malamulo olandila kwa achikulire ngati mankhwala okhawo ochizira kapena osakaniza ndi mapiritsi ena ochepetsa shuga:

1. Mankhwalawa amamwetsa kapena kudya. Nthawi zambiri, koyamba mlingo ndi 500-850 mg patsiku, logawidwa zingapo. Kukula kwake kumakhudzana mwachindunji ndi kuchuluka kwa shuga m'magazi.
2. Mlingo wokonza ndi 1500-2000 mg patsiku, umagawidwa pawiri Mlingo umodzi kuti usanthedwe ndi zomwe zimachitika m'matumbo.
3. Mlingo wambiri watsiku ndi tsiku sayenera kupitirira 3000 mg.

Kuphatikiza ndi insulin:

• Mlingo woyambirira wa metformin ulinso 500-850 mg katatu patsiku, kuchuluka kwa insulin kumasankhidwa payekhapayekha kwa shuga m'magazi.

Kwa ana a zaka zoyambira 10, metformin imayikidwa 500-850 mg kamodzi patsiku chakudya. Kusintha kwa Mlingo ndikotheka pambuyo pakugwiritsa ntchito kwa milungu iwiri. Mlingo woyenera kwambiri sayenera kupitirira 2000 mg patsiku, umagawidwa pawiri.

Pali mitundu yotalikilapo ya mapiritsi omwe mungamwe kamodzi patsiku. Mlingo amasankhidwa ndikuwonjezeka payekhapayekha, mankhwalawa amagwiritsidwa ntchito pamenepa, nthawi zambiri mukatha kudya chakudya chamadzulo.

Metformin pa mimba ndi mkaka wa m`mawere

Panalibe maphunziro okwanira maimelo. Zowonera zochepa zikuwonetsa kuti palibe zolakwika zomwe zimapezeka mwa ana osabadwa, pomwe mayi woyembekezera amatenga mankhwalawo. Koma chilangizocho chikuyankha kuti mayi wam'tsogolo azidziwitse adokotala za momwe aliri, kenako akuwona ngati asintha kukonzekera insulini, ngati pakufunika kutero.

Zimatsimikiziridwa kuti chinthucho chimapukutidwa limodzi ndi mkaka wa m'mawere, koma zovuta za ana sizinawonebe. Ngakhale izi, sizingatengere mkaka wa m`mawere, ndikofunikira kuti muzitsirize kuti zisayambitse zovuta zosayembekezereka mwa mwana.

Zotsatira zoyipa ndi bongo

Nthawi zambiri, mukamamwa mankhwalawa, kugaya kwam'mimba kumakhala ndi vuto: zimbudzi zam'mimba, mseru, kusanza kumawonekera, kusintha kwa zakudya, komanso kusowa kudya kungawonongeke. Nthawi zambiri, zizindikirozi zimasinthika - zimachitika kumayambiriro kwa chithandizo ndipo zimazimiririka zokha monga zimawonekera.

Zovuta zina:

1. Khungu: kuyabwa, zotupa, malo ofiira.
2. Metabolism: osowa kwambiri lactic acidosis. Pogwiritsa ntchito mankhwalawa kwa nthawi yayitali, kumatheka B nthawi zina.₁₂.
3. Chiwindi: kuphwanya magawo a labotale, hepatitis. Zosintha zimasinthidwa ndikudutsa pambuyo pakuchotsedwa.

Ngati zotsatira zoyipa sizisokoneza thanzi lathunthu, mankhwalawa amapitilizidwa popanda kusintha. Zotsatira zikachitika zomwe sizikufotokozeredwa m'malamulo ovomerezeka, muyenera kudziwitsa dokotala za iwo ndikutsatira malangizo ake.

Mankhwala osokoneza bongo a metformin amapezeka pokhapokha ngati mankhwalawo amatengedwa kwambiri kuposa kangapo tsiku lililonse. Nthawi zambiri imadziwoneka yokha ndi lactic acidosis - dongosolo lamkati lamanjenje limakhala lopsinjika, kupuma, zamtima komanso zovuta zowonekera m'machitidwe zimachitika. Pankhaniyi, kugonekedwa kuchipatala ndikofunikira!

Malangizo apadera

Opaleshoni. Metformin iyenera kuchotsedwa masiku awiri asanafike opaleshoni yomwe idakonzedwa ndipo osasankhidwa pasanadutse masiku awiri itatha.

Lactic acidosis. Ndi zovuta kwambiri, ndipo pali zinthu zina zomwe zikuwonetsa kuwopsa kwake. Izi zikuphatikiza:

• kulephera kwambiri kwaimpso
• nthawi yomwe sizingatheke kuwongolera kuchuluka kwa shuga m'magazi,
• kupeza kuchuluka kwa matupi a ketone mthupi,
• njala idagwa
• mavuto akulu a chiwindi
• uchidakwa wosatha.

Poyerekeza ndi momwe mungatengere metformin, mowa uyenera kusiyidwa ndi kukonzekera komwe kumatha kukhala ndi ethanol (tinctures, solution, etc.)

Ntchito ya impso. Chenjezo makamaka liyenera kugwiritsidwa ntchito ndi anthu achikulire omwe amakonda kumwa mankhwala a antihypertensive, okodzetsa komanso osapatsa mankhwala a antiidal.

Mankhwala ena omwe angayambitse mavuto osafunikira nthawi yomweyo:

• danazol
• chlorpromazine
• β2-adrenomimetics mu mawonekedwe a jakisoni,
• nifedipine
• digoxin
• mathitidine
• vancomycin.

Zakugwiritsa ntchito kwawo, muyenera kuchenjeza adokotala pasadakhale.

Ana kuyambira zaka 10. Kuzindikiritsa kuyenera kukhazikitsidwa asanaikidwe ndi metformin. Kafukufuku watsimikizira kuti sizikhudza kutha ndi kukula. Koma kuwongolera magawo awa kuyenerabe kukhala koopsa, makamaka pazaka za 10-12.

Zina Kuti muchepetse kunenepa, tikulimbikitsidwa kuti muzitsatira zakudya kuti chakudya chamagulu azigwiritsa ntchito tsiku lonse. Tsiku lomwe muyenera kudya osachepera 1000 kcal. Njala yoletsedwa!

Zochita zamankhwala

Mankhwala ali ndi zovuta:

amachepetsa kutulutsidwa kwa glycogen ku chiwindi, amalepheretsa kuchuluka kwa shuga m'magazi, kutsekereza kupangika kwa shuga m'matumbo ndi mapuloteni, kumachepetsa kuyamwa kwa shuga m'matumbo, kukhazikitsa cholesterol, kusintha metabolism wamafuta, kumalimbikitsa kuyamwa kwa mafuta mu minofu.

Zinthu zonsezi zimathandizira kukhazikika, ndipo nthawi zambiri, zimachepetsa. Komabe, si aliyense amene zinthu zimamuyendera bwino. Nthawi zambiri izi zimachitika chifukwa chakuti odwala:

Mankhwala amagwiritsidwa ntchito muyezo wosakwanira, samatsatira mankhwalawo, samakhudzana ndi zakudya, mankhwalawa samadziwika ndi wodwala wina.

Njira yogwiritsira ntchito

Metformin imapezeka mu mitundu yosiyanasiyana: 500, 850 kapena 1000 mg. Ndikwabwino kuyamba ndi mlingo wocheperako wa 500 mg ndi kumwa nthawi. Zotsatira zakuzama kwambiri kwa thupi lopanda nthawi yosinthika zimatha kuyambitsa zovuta zina. Mwachitsanzo, mavuto ammimba: nseru, kusanza, kutsegula m'mimba, kusintha kukoma.

Sabata iliyonse, mlingo wa mankhwalawa uyenera kuchuluka ndi 500 mg. Kuchuluka kwa patsiku sikuyenera kupitirira 2000 mg, apo ayi zosasangalatsa zomveka zidzachuluka.

Mutha kuzitenga m'njira zitatu:

musanadye, ndikudya, musanagone.

Pa mankhwala zinthu zina ziyenera kusiyidwa, apo ayi kugwiritsa ntchito chinthucho sikudzakhala kwenikweni. Awa ndi “monga atanyamula” tirigu, mbale za mbatata, pasitala, nthochi ndi zipatso zouma. Palibe choletsa mchere.

Njira yovomerezedwayo ndikuigwiritsa ntchito masabata atatu, mutatha kupuma kwa mwezi umodzi, apo ayi thupi lidzazolowera chinthucho ndikusiya kuyankha mwachidwi.

Mankhwala otchuka mdziko la omanga thupi. Momwe mungatenge METGHIN YOTHANDIZA? Malangizo Chifukwa chiyani mukuopa? Kodi mungalembe makilogalamu angati? MALO OGANIZA BWANJI? Ndemanga za madotolo. Zotsatira za matenda ashuga.

Moni Lero powunika kwanga tikambirana za mankhwala a odwala matenda ashuga, omwe, chifukwa cha "mbali" yokhudzana ndi kuchepa thupi, kulumikizana ndi chidwi komanso maubwino angapo azaumoyo, omwe takambiranawa pansipa, akhala akukonda posachedwa ndi omanga thupi osiyanasiyana ndipo anthu ena osimidwa, makamaka azimayi - kuwonda. Metformin dzina lake. Iye ndi Glucophage ndi Siofor - awa ndi ochokera mayina odziwika bwino, ndi khutu.
Zofananira zina za Metformin zomwe zimagwira ntchito yomweyi:

Bagomet, Metfogamma, Glycon, Metospanin, Glformin, Glimfor, Sofamet, Formmetin, Langerin, Metadiene, Fomu Pliva, Novoformin, Diaformin

✔️ NJIRA YA ZIWANDA

Kwa nthawi yoyamba yomwe ndinamva za metformin kuchokera kwa wachibale wodwala matenda ashuga. Sindinamuwone pafupifupi miyezi isanu ndi umodzi kapena kuchepera pang'ono, ndipo pamsonkhano sindimazindikira kuti anali woonda bwanji. Mwambiri, mawonekedwe a matenda ashuga, ndimakonda kuwona china chake chopweteka: miyendo yotupa, nkhope yooneka ngati mwezi, kunenepa kwambiri. Ndipo apa, patsogolo panga, mkazi wathanzi labwino kwambiri anali atakhala, mooneka pang'ono. Mwachibadwa, ndinachita chidwi ndi chifukwa chomwe mitundu yotereyi imabereka modzidzimutsa. Zinapezeka kuti zonse zomwe zinali kuti mu pulogalamu imodzi yokhudza zaumoyo (Elena Malysheva, mwina) mankhwalawa adapakidwa poti wachibaleyo adachita chidwi kuti, malinga ndi iye, ngakhale osadwala, adzagula pambuyo poti wayang'ana. Pulogalamu iyi, kuwonjezera pa kutenga matenda a shuga, Metformin adalimbikitsidwa kuti achepetse thupi, pamavuto okhala ndi pakati, popewa khansa, ndipo adatchedwa machiritso okalamba.

✔️ NKHANI YOPHUNZITSIRA, KUDZICHEPETSA KWAMBIRI

Kachiwiri mwamuna wanga adandidziwitsa za chida ichi, ndipo, nayenso, anali munthu wochita masewera olimbitsa thupi. Anagula Metformin kuti ayesetse kuchepetsa "kunenepa" kolemera, komwe sikunayendetse mwanjira iliyonse. Kwa abwino, malingana ndi malingaliro ake, kunali kofunikira kutaya 2 kg m'malo osafikirika - pamimba ndi m'mbali. Njira zina zonse zovomerezeka zayesedwapo ndipo pazifukwa zina zakhumudwitsidwa. Ndinaganiza zothamangitsa njirayi. Ndinkayang'ana ndikumaliza

✔️ MUNGATANI KUTI METGHIN YOTHANDIZA, MALANGIZO OGULITSIRA

Mwamunayo sanayang'ane malangizo aboma, koma adavomera monga adalangizidwa ndi abwenzi ake:

1. Yambani musanadye, kapena nthawi yakudya.
2. Yoyambitsidwa ndi Mlingo wa Metformin 500 mg, kenako ndikupanganso mlingo - 850 mg, kotero kuti thupi limazolowera ndipo osayankha poyambira "zotsatira zoyipa" zoyambira: nseru kapena kutsegula m'mimba.
3. Adatenga 2 pa tsiku
4. Njira yovomerezeka inali pafupifupi masabata atatu. Palibe.
5. Nthawi yomweyo kulima mu masewera olimbitsa thupi kuti muthe kusintha. Ndikudziwa kuti m'mbuyomu mutatenga Metformin kuti muchepetse thupi, masewera olimbitsa thupi adayimitsidwa, chifukwa amakhulupirira kuti lactic acid yomwe idatulutsidwa panthawi yolimbitsa thupi idayamba kuchita zosayenera, koma pambuyo pake zidawoneka kuti zimatsutsidwa. Komabe, mapiritsi awa ochokera m'gulu la anthu oonda kwambiri, ndiye kuti, musangotanthauza kukwaniritsa zotsatira zolimbitsa thupi, monga Carnitine.

Zochitika:

• Kwa nthawi yonseyi amuna anga sanadandaule za zovuta zilizonse. Osasanza, kusanza kapena kutentha kwam'mimba

• Pali zochepa zodya. Ndinganene kuti sinditha kuwona chakudya. Koma chodabwitsa chakutenga Metformin, ngakhale kuwonda, ndikuti ngakhale zilibe kanthu momwe ungayesere kudya, ngakhale mutakhala osangalala bwanji ndi zotsatira zoyipa, simungathe kuchita izi - zakudya zochepa zopatsa mphamvu ndizoletsedwa ndi malangizo ogwiritsira ntchito, muyenera kudya osachepera 1000 kcal patsiku.

• Wotembereredwa kuti ndimakakamiza chakudya chochuluka. Ngakhale anagona mwachizolowezi, osati zochulukirapo. Zikuwoneka kuti, zotsatira za "kudana ndi chakudya" zimakhudzidwa.

• Kwa nthawi yochepera mwezi umodzi, adachepetsa thupi, kumwa metformin, pa "2" yovuta yomweyo
• Ndinkakhuta kwambiri, ndikupitilizabe kugwira ntchito m holo mu dzina la "zomangamanga minofu". Nthawi yochepetsa thupi yatha.

Nditawona amuna anga, ndidalimba mtima, osawona zoyipa. Ndipo ataona kuti wasiya mapulani ake, adaganiza kutsatira mapazi ake. Ndinasiyanso kutaya makilogalamu awiri, kenako ndimadziona kuti ndine wokondwa kwambiri.

Ndikayang'ana m'mbuyo, nditha kunena kuti uwu ndi wopenga komanso kutchova njuga kwa madzi oyera. Zomwe zili kumbali yanga, zomwe zili ndi mwamuna wanga: Muyenera kudziwa kuti ndinu athanzi, muyenera kukhala okonzekera zovuta zomwe zimakhala ndi ngolo ndi ngolo yaying'ono.

• Koma (1) panthawiyo ndinali wokonzeka "kukhala kamodzi kokha" ndikuwotcha zonse ndi moto "- chaka chodziwika bwino chodumphadumpha chidasiya chizindikiro.

• (2) Kulephera kudzikoka okha ndikupanga masewera

• Komabe (3) yesetsani kutaya makilogalamu 1-3 osachita chilichonse, kuchita mantha monga momwe ndimafunira

• Ndipo, pomaliza pake, (4), ndidawerenga zolemba zosiyanasiyana, mabuku, ndemanga zokhudzana ndi metformin, zomwe zimawoneka ngati wanga ngati mthenga wa kumwamba.

- kuti imatenga nthawi yayitali moyo ndikuchepetsa kukalamba kwa anthu, ngakhale atakhala ndi matenda ashuga kapena, m'malo mwake, ndi olimba, odzala ndi mphamvu komanso athanzi)))

Kafukufuku watsopano wa Cardiff University, UK, 2014, omwe adakhudza anthu 180,000, adawonetsa kuti Metformin imawonjezera chiyembekezo chokhala ndi moyo osati kokha kwa odwala omwe ali ndi matenda ashuga, komanso mwa anthu omwe alibe matendawa. Zambiri zidapezekanso pang'onopang'ono panjira yaukalamba pamankhwala.

✔️ METGHIN - MALANGIZO OGULITSIRA

Mankhwala Metformin, zikuwonetsa

Monga mukuwonera, Metformin imavomerezedwa mwalamulo kwa odwala matenda ashuga, ndizo zonse. Zosangalatsa zomwe zatsala zili pachiwopsezo chanu komanso pachiwopsezo chanu.

Ndi mndandanda wochepetsera wotere, pepala la zotsutsana likungodabwitsanso:

Momwe mungatenge metformin. Mlingo

Kugwirizana ndi mankhwala ena:

Ndikupatsani chidwi kuti zotsatira za kutenga Metformin zitha kukhala kuchepa kwa vitamini B12, komwe ndikofunikira kwambiri kuti mukhale ndi thanzi labwino. Chifukwa chake, muyenera kusamalira kumwa ma protein B12 mu kapangidwe kake.

Nkhani yakumalizira yatsirizika, ndikutembenukira ku gawo losasankhidwa.

Chifukwa chake, kamodzi m'mawa ndimauza amuna anga kuti: "Bwerani mundipatse tabletosiki yanga iyi, ndiyesa chiyani ndi momwe."
Mwa njira, pakumafunsa kwanga komanso momwe amamugwiritsira ntchito, ananena kuti andithandizenso.
Pakufunsira koyamba, adapereka ndikubisala patali. Zouziridwa, Ine Ndidapanga mphika wa khofi, ndidadya ndi nthochi, ndikupanga sangweji, ndikusangalala, ndikupita kokayenda ndikudziwa kuti ndikapanga chinthu changa, ndipo piritsi la chakudya likadakhala langa.

Nthawi yapita. Choyeretsedwa m'mimba mwake. Ndinali ochenjera ndipo ndimatembenuza madigiri 180, ndinapita kunyumba. Zingachitike - sizinali zofunika kwambiri, zinthu izi. Ndinakumbukira zabwino zoyambitsa ndi malangizo a Metformin.

Ndipo zili choncho. Osati mwachangu, koma kutsekula m'mimba kunayamba patangopita maola ochepa. Zabwino kwambiri, zapamwamba kwambiri) Zinkawoneka kwa ine kuti pamlingo wotere umatha kuchepa thupi kuposa 1 kg patsiku popanda kupindika.

Madzulo ndidadziwitsidwa kuti chifukwa cha ichi ndi chakudya changa cham'mawa, chodzaza ndi mafuta othamanga.

1. Zoyala "zoyera" (mkate, pizza, masikono),
2. Msuzi ndi uchi,
3. Confectionery ndi zakumwa zoziziritsa kukhosi,
4. Mavwende, nthochi, Persimmon ndi mphesa,
5. Mayonesi ndi ketchup,
6. Mowa (mowa - makamaka).

* Mndandanda wonsewo ukhoza kupezeka patsamba lodziwika bwino.

Banana ndi masangweji. Zimapezeka kuti sizipatula zoyipa mwanjira ya matenda am'mimba, izi ndi TABU. Kapena khalani okonzeka kukhala pachimbudzi, ndikulota za muyaya komanso zokongola.

Mwamuna wanga sanakhale ndi mavuto otere, popeza palibe zakudya zofananira)
Sindinafunse, koma sanachenjeze.

Koma amayi, bwanji? Kupatula masikono ndi maswiti, nditha kutaya 100% popanda thandizo la metformin ndi mankhwala ena onse. Kale anali ndi zoterezi. Ndipo pamenepo ndinachepetsa thupi mwachangu kwambiri.

Mapeto ake, ndidakhala milungu iwiri. Komabe, anapitabe.

• Metformin adagwiritsanso ntchito "chikwapu" ngati chida chothandizira: adadya cholakwika - pezani chilango. Khalani mchipinda chogwiritsira ntchito ndikuganizira za chikhalidwe chanu)))

• Zimathandiza, mukudziwa, kuganizira momwe mumagwiritsira ntchito zakudya. Tsopano ndidaphunzira "chakudya champhamvu". Pafupifupi phunzirani.

• Kuchokera pazotsatira zoyipa, adazindikira kuti ubongo wawachepa, ndiye kuti atatha masiku awiri adayamba kuchepa ndikuganiza molimba. Osati mpaka momwe zimafunira kuti discontinuation ya mankhwalawa, komabe muwone mbali iyi.

Malinga ndi madokotala, kuyambira 1 mpaka 4 kg.

Koma malinga ndi nkhani za mwamuna wake, chifukwa choti amalimbana ndi vuto la kudya, anthu amachepetsa thupi pazizindikiro zowoneka bwino.

Ndipo zotsatira zanga ndi motere: opanda 1.5 kg. Pakupita milungu iwiri.Nditha kupilira motalika - plumb ikhoza kukhala yofunika kwambiri, ndikutsimikiza. Popeza ndizowopsa kudya (a), mwadzidzidzi ndidzadya kena kake, chilakolako cha ndewu chimachita nkhondo. Sindikudziwa pamlingo uti, wamaganizidwe kapena thupi. Sindikumvetsa.

Izi ndi zomwe ndimafuna, koma. Pamtengo wake?
Mwina ayi inde.

Sichikondi kapena kuchita nawo ulendo wautali wopanda malingaliro ndi zovuta zochititsa manyazi. Ndipo kung'ung'udza m'mimba ndi zotsatira zabwino kwambiri kuchokera ku zomwe zingatheke. Mowa mukamamwa metformin, mwa njira, iyenera kuphatikizidwanso. Popanda "koma" ndi "pang'ono" sichowerengeka. Kuphatikiza kowopsa.

Komabe ndikufunabe kuti ndikhulupirire, ngati chitonthozo cha mavuto onse omwe anakumana nawo, kuti Metformin idzasewera gawo lina pochepetsa kuchepa. Ngakhale ndikudziwa kuti sizili choncho. Mlingo siofanana.

"Mlingo wogwira ntchito wa metformin ndi 1,500-22,000 mg; ndi mu Mlingo uwu pomwe prophylactic mphamvu ya metformin yolimbana ndi atherosclerosis ndi khansa imawonekera (nthawi zambiri amayamba ndi 500 mg ndikuwonjezeka pang'onopang'ono)."

✔️ NDIPONSO ZABWINO KWAMBIRI? PRICE

Imapezeka mu mitundu yosiyanasiyana (Metformin 1000, 850 ndi 500 mg) kuchokera kwa opanga osiyanasiyana:
Pali Metformin Canon, Teva, Ozone, ndi Gideon Richter.

Ambiri omwe amatsutsa Metformin "Ozone", akuti ena samva izi. Mwina ingokhalani m'madziwe oyaka.
Richter adalimbikitsidwa kwa mwamuna wake, ndipo adayimilira. Monga mukuwonera, pali zotsatira. Ngakhale dzina lachilendo, lopangidwa ku Russia.

PRICE YOKUTHENGA MALO MU PHARMACIES ndiyokwera mtengo. Kuyambira 100 mpaka 300 ma ruble, kutengera mlingo, kaya wopanga ndi ndani.

✔️ METGHIN, ZOCHITITSA ZA A DIPOTI

Monga momwe ndikudziwira, wolimbikitsa wofunikira kwambiri wa mankhwalawa ndi Dr. Myasnikov. Amamuwonjezera m'mabuku, amamuyamika pa wayilesi.

Pofuna kuti pasakhale zopanda maziko, zolemba m'mabuku (m'makope onse omwe ndili nawo, palibe pomwe pamatchulidwa za metformin mbuku limodzi lokha, m'njira zina zonse, koma malankhulidwe abwera.)

Metformin nthawi zambiri ndi mankhwala osangalatsa kwambiri. Amachepetsa kukana (kukana) kwamasempha kwa insulin. M'mabuku anga onse omwe ndimatchulawa ndikufotokozera izi - chifukwa kukana insulini ndiko maziko a matenda ambiri, osati matenda a shuga okha, komanso oncology, kunenepa kwambiri, atherosclerosis. Metformin ndi yothandiza kwambiri kotero kuti imaperekedwa kwa odwala onse omwe ali ndi matenda amtundu wa 2 ngati mankhwala a mzere woyamba. Nthawi yomweyo, Metformin imaphatikizidwa mwatsatanetsatane mndandanda wa mankhwala omwe amagwiritsidwa ntchito ngati khansa chemoprophylaxis. Kutsimikiziridwa - kumachepetsa chiopsezo cha matenda a mtima ndi stroko mu odwala matenda ashuga. Ndipo amalimbikitsanso ovulation, yomwe imafotokoza momwe amagwiritsidwira ntchito azimayi omwe ali ndi vuto losabala. Ndipo kudya kwake kumayendetsedwa ndi kunenepa. Avereji ya 2-4 kg. Omwe adatsimikiza kuti amagwiritsidwa ntchito mwa anthu onenepa kwambiri.

Chifukwa chake, matenda ashuga, oncology, kunenepa kwambiri, atherosulinosis, kupewa matenda a mtima ndi sitiroko, kubereka. Ngati izi zikukuvutitsani, dokotala amalimbikitsa kuti muphunzire Metformin ngati mankhwala omwe mungamwe.

Komanso, kuchokera ku buku lina:

"1) Kafukufuku wazinthu zazikuluzikulu zawonetsa motsimikiza kuti metformin, monga palibe mankhwala ena aliwonse, amateteza mitsempha yathu ya magazi ku matenda a atherosclerosis ndikuletsa kukula kwa matenda a mtima ndi stroko (vuto lalikulu kwa odwala matenda ashuga!).
2) Kafukufuku wina adawulula kuti metformin imateteza anthu odwala matenda ashuga ku tsoka linanso - oncology! Lero Metformin yaphatikizidwa mwatsatanetsatane mndandanda wa mankhwala a khansa chemoprophylaxis!
3) Awa ndi amodzi mwa mankhwala ochepetsa nkhawa kwambiri omwe samangowonjezera phindu, koma, m'malo mwake, amathandizira kutaya ma kilogalamu a 3-4. (Madokotala nthawi zina amagwiritsa ntchito izi popereka mankhwala a metformin kwa anthu omwe ali ndi shuga koma onenepa kwambiri.)
4) Amagwiritsidwa ntchito pokhapokha pothana ndi matenda ashuga, komanso mankhwalawa osabereka - amathandizira kuvunda kwa mazira! Imathandiza pa matenda potengera insulin: metabolic syndrome, kuchepa kwamafuta kwa chiwindi, kunenepa kwambiri, ma ovary a polycystic.

Zomwe muyenera kukumbukira musanayambe

"Zotsutsana? Inde, ali! Chiwerengero chochepa kwambiri cha odwala chidalembetsedwa, pomwe amatenga Metformin, zovuta zowoneka bwino - kuphwanya kwakukulu kwa acid-base balance. Chifukwa cha kupha kumene kwa vuto ili, kusankha odwala omwe metformin idakonzedwa imatengedwa kwambiri. Ngati pali vuto la impso kapena osokoneza, mwina sangapatsidwe.
Onetsetsani kuti mwayang'ana kuchuluka kwa mankhwala a creatinine musanapange mankhwala. Omwe atatenga metformin sayenera kupitirira 130 mmol / l mwa azimayi ndi 150 mmol / l mwa amuna. ”

“Chinanso chomwe chimayambitsa mikangano ndi kulephera kwa mtima, uchidakwa, komanso kulephera kwa chiwindi. Kafukufuku akuwonetsa kuti ngati metformin ikaperekedwa mosamala, chiopsezo cha acidosis chachikulu chimakhala chochepa. ”

"Koma chomwe chimachitika kwenikweni ndimavuto am'mimba: kupindika, kutsukidwa, kulemera, kulawa kwazitsulo mkamwa. Munthawi zochulukirapo, muyenera kukhala opirira: pakatha sabata kapena awiri, kawirikawiri zonse zimatha. Chidule: Timakonda kupereka khola ndi zomwe tafotokozazi za dyspepsia. Sizingaperekedwe limodzi ndi metformin: amachepetsa kuchuluka kwa zotulukazo ndikuwonjezera kuchuluka kwake m'magazi. ”

Kuchokera kwa ine kuti ndifotokoze mwachidule:

• Palibe mowa

• Muyenera kukhala athanzi kwathunthu.

• Kumbukirani kuti kutenga Metformin kuli ndi zotsatira zoyipa za vitamini B - B12.

• Osatengera limodzi ndi mankhwala othandizira kapena othandizira mankhwala osokoneza bongo omwe ali ndi zomwe ali nazo kuti afulumizitse ntchitoyi

• Ngati mutadya china chake cholakwika, zikhala zovuta.

- Ndikakhala ndekha (malinga ndi maubale), ndipo ndili ndi cholinga chotaya makilogalamu pang'ono pofika tsiku linalake, ndimakhala ndi mphamvu zokwanira kusiya maswiti m'dzina la cholinga chachikulu ndikusiya mowa kwa nthawi yonse yodya.
- Ndili tchuthi, kapena zowoneka bwino za ntchitoyi ndikuti kuthamangira mwadzidzidzi kulowa munyumbamo sikungadziwike.

Ngakhale malingaliro osakanikirana mutatenga Metformin kuti muchepetse thupi, ndilibe ufulu womupatsa mtengo wotsika. Mukamagwiritsidwa ntchito mongaalangizidwa (kwa matenda ashuga) - Zotsatira zake zimakhala zabwino.
Kuphatikiza apo, nthawi yoikidwayo iyenera kuvomerezedwa ndi dokotala. Mwakutero, malangizo, akuwonetsa kuti awa ndi mankhwala omwe mumalandira. Ngakhale amazigulitsa mwaulere komanso.

--------- ZOTHANDIZA ZANGA ZA KUPEMBEDZA ---------

Kufotokozera za mankhwalawa

Metformin imapangidwa ndi makampani ambiri azamankhwala pansi pa mayina osiyanasiyana ogulitsa. Ili ndi fomu ya piritsi. Kuphatikiza pazomwe zimagwira ntchito (metformin hydrochloride), kukonzekera kumakhala ndi zinthu zina, makamaka, wowuma, microcrystalline cellulose, magnesium stearate, povidone.

Zochita zamankhwala zimapangidwa kuti:

• Kuchepetsa gluconeogenesis m'chiwindi (kapangidwe ka glucose kuchokera ku mankhwala osagwiritsa ntchito carbohydrate),
• kuchepa kwamatumbo a glucose,
• kukulitsa mphamvu zake zotumphukira,
• kuchuluka kwa chidwi cha insulin,
• utachepa triglycerides ndi LDL,
• kukhazikika kwa thupi.

Kuchepetsa thupi pamene kunenepa kwambiri kumachitika chifukwa cha kuthamanga kwa makutidwe ndi michere yamafuta, kuchepa kwa adsorption ya chakudya kuchokera kuzakudya, komanso kuchuluka kwa shuga ndi minofu. Chifukwa cha kuchuluka kwa insulin yosakanikirana, kuchepa kwamatenda kumachitika, komwe kumalepheretsa kudya kwambiri.

Ndikofunikira kukumbukira kuti kagayidwe kachakudya ka michere kamatha kubwezeretsedwanso kudzera m'njira yophatikizidwa.

Mutatha kumwa mapiritsiwo, kuchuluka kwa metformin kumadziwika pambuyo pa maola 2,5. Kuchotsa chinthu kumachitika ndi impso osasinthika.

Zizindikiro zogwiritsidwa ntchito

Metformin imaphatikizidwa pamndandanda wa mankhwala omwe amaperekedwa kwa odwala omwe ali ndi BMI pamwambapa 27 ndi World Gastroenterological Organisation (GGO).

Ndiye kuti, mankhwalawa amagwiritsidwa ntchito pamaso pa kunenepa kwambiri:

• matenda ashuga
• polycystic ovary.

Komanso, kutumikiridwa kwa Metformin kudzakhala koyenera pamene odwala omwe ali ndi kunenepa kwambiri atenga mankhwala a antipsychotic, omwe amachepetsa chidwi cha maselo kuti apange insulin.

Zochizira kunenepa kwambiri mu odwala matenda ashuga, onse a Metformin monotherapy komanso kuphatikiza kwake ndi mankhwala ena ochepetsa shuga kapena insulin amachitidwa.

Momwe mungagwiritsire ntchito?

Mlingo woyambirira wa chinthu ndi 500-850 mg. Ndikofunika kumwa mankhwalawa katatu patsiku (mutadya kapena mutatha kudya). Piritsi imamezedwa popanda kutafuna ndikutsukidwa ndi madzi.

Pambuyo masiku 10-15, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga, komwe kumakupatsani kusintha kwa regimen.

Ngati Metformin adalandira mwana wazaka zopitilira 10, chithandizo ndi motere:

• piritsi limodzi - 500 kapena 850 mg,
• Kamodzi patsiku chakudya chamadzulo,
• pambuyo masiku 10-15, mlingo kumawonjezeka mpaka 2000 mg, omwe amatengedwa katatu patsiku.

Contraindication

Ngakhale mankhwalawa amatha kuchotsa kunenepa kwambiri ndikugwiritsa ntchito, sikuti amagwiritsidwa ntchito kwa wodwala aliyense yemwe ali ndi kunenepa kwambiri.

Mndandanda wazopondera waperekedwa:

• ketoacidosis, matenda a shuga kapena chikomokere,
• aakulu aimpso / chiwindi kulephera,
• Matenda omwe minofu ya hypoxia (mtima / kupuma imalephera, vuto la mtima) imayamba
• lactic acidosis, kuphatikizapo mbiri ya
• Kutsatira zakudya zamafuta ochepa,
• uchidakwa
• chidwi chachikulu ndi gawo lalikulu la mankhwalawo.
• mimba ndi mkaka wa m`mawere
• ana ochepera zaka 10 (akatswiri ena amati ndibwino kugwiritsa ntchito mankhwalawa kuyambira azaka 18).

Metformin sinafotokozeredwe kwa odwala okulirapo kuposa 65, komanso masiku awiri chisanachitike mayeso a X-ray pogwiritsa ntchito zosiyana ndi masiku awiri atatha.

Mlingo wa mankhwalawa muubwana umakula pokhapokha kudziwa kuchuluka kwa shuga m'magazi.

Zotsatira zoyipa ndi bongo

Chimodzi mwazinthu zomwe zimasiyanitsa ndi Metformin ndi chiopsezo chowonjezeka cha thupi pamapiritsi, makamaka ngati mankhwalawa sanawonedwe.

Mukamamwa mankhwalawa, odwala akhoza kudwala:

• mseru ndi kulimbikitsa kusanza, kusowa kwa chakudya, kulawa kwazitsulo mkamwa, kusefukira, kukhumudwa, kupweteka m'mimba,
• kuchuluka kwa magazi a lactic acid (lactic acidosis),
• Vitamini B12 akusowa
• kuchepa magazi
• achina,
• zotupa pakhungu.

Zizindikiro za Dyspeptic nthawi zambiri zimasokoneza gawo loyambira ndipo nthawi zambiri zimachoka popanda kusokonezedwa kunja. Kuti muchepetse vutoli, antispasmodics ikhoza kutumizidwa.

Zizindikiro mu mawonekedwe a kupweteka kwa minofu, nseru, kusanza, kutsegula m'mimba, kupuma mwachangu, kukhudzika kwa chikumbumtima kumapereka umboni wa kuchuluka kwa lactic acid.

Kuchita ndi mankhwala ena

Amaphatikizika kuphatikiza Metformin ndi mankhwala okhala ndi ayodini omwe amakhala ndi iodini, ndi mowa ndi mankhwala, momwe ethanol ilipo. Mukamagwiritsa ntchito pamodzi ndi zotchedwa loop diuretics, chisamaliro chapadera chimafunikira.

Machitidwe a Metformin amalimbikitsidwa ngati agwiritsidwa ntchito limodzi ndi:

• angiotensin kutembenuza ma enzyme (ACE) zoletsa,
• zochokera sulfonylurea,
• insulin
• acarbose,
• cyclophosphamide
• salicylates.

Mankhwala a Glucocorticosteroid, mahomoni a chithokomiro, nicotinic acid, thiazide diuretics, m'malo mwake, amachepetsa kugwiritsa ntchito mapiritsi.

Metformin ndi zakudya

Ndikofunika kumvetsetsa kuti mankhwalawo sangathe kuwotcha mafuta m'thupi. Ndi zakudya zopangidwa ndi zakudya zophatikizidwa bwino, zimathandiza kugwiritsa ntchito mafuta omwe amapezeka, omwe pambuyo pake amachititsa kulemera.

Chifukwa chake, muyenera kutsatira zakudya zomwe zimaperekedwa kukanidwa kwa zakudya zamafuta kwambiri. Kumbali inayi, simungasinthe kupita ku chakudya chamafuta ochepa, chomwe Metformin ndi yoletsedwa.

Zochita zolimbitsa thupi

Ngati munthu ali ndi mavuto ndi mapaundi owonjezera, ayenera kusamalira mokwanira zolimbitsa thupi. Kuphatikiza iwo ndi mankhwala othandizira, muthamangitsa kuchepa thupi, ndikuwonjezera mphamvu ya thupi.Ndi moyo wokhala chete, simuyenera kudalira zotsatira zabwino.

Zotsatira zake zitha kuwoneka ndi njira yolumikizidwa.

Kuphunzitsa, komanso kugwiritsa ntchito Metformin, kuyenera kuvomerezana ndi adokotala. Masewera ena amatsutsana m'matenda ena.

Gwiritsani ntchito mafuta a chiwindi hepatosis

Zinatsimikiziridwa kuti poyerekeza ndi mtundu wa matenda ashuga amtundu wa 2 ndi kunenepa kwambiri, chiopsezo chotenga magazi m'chiwindi (mafuta a hepatosis) komanso osamwa mowa kwambiri chikuwonjezeka. Makamaka, kuchepa kwamafuta kumachitika pafupifupi 60% ya odwala omwe alibe shuga.

Imodzi mwa mankhwalawa ndi Metformin, yomwe imathandizira kuchepa kwakukulu kwa hyperinsulinemia komanso kutsika kwa insulin.

Mlingo wa mankhwala amakhazikitsidwa ndi adokotala. Kusintha kwa mlingo wokhala ndi mafuta a chiwindi hepatosis m'mwamba kapena pansi kumachitika pambuyo pakupereka mayeso oyenera.

Mtengo wa mankhwalawa umatengera zomwe zili mu metformin piritsi limodzi komanso kuchokera kwa wopanga.

Mitengo yotsika mtengo:

• 500 mg - kuchokera ku 90 ma ruble. (Ma PC 30.) Ndipo kuchokera ku ma ruble 110. (Ma 60 ma PC.),
• 850 mg - kuchokera ku 95 ma ruble. (Ma 30 ma PC.) Ndipo kuchokera ku ma ruble 150. (Ma 60 ma PC.),
• 1000 mg - kuchokera ku ma ruble 120. (Ma 30 ma PC.) Ndipo kuchokera ku ma ruble 200. (Ma 60 ma PC.).

Mankhwala ogulitsa pa intaneti nthawi zambiri amapereka Metformin pamitengo yotsika mtengo. Chachikulu ndikutsimikiza kuti ndi zoona.

Pali mndandanda waukulu wamankhwala, womwe ndiwothandiza womwe umayimiriridwa ndi metformin.

Zina mwa izo ndi:

Ngati Metformin ndi yoletsedwa pa chifukwa chilichonse, m'malo mwa mankhwalawa omwe atchulidwa pamwambapa, atha kuyikidwa m'malo mwake:

1. Glucovans. Kuphatikiza pa metformin, glibenclamide ilipo, yomwe kuchitapo chake ndikulimbikitsa kukonzanso katemera wa insulin. Komabe, zonse pamodzi zimathandizana. Glucovans imalembedwa mtundu wachiwiri wa matenda ashuga, pomwe glycemia imayendetsedwa bwino.
2. Gluconorm. Zomwe zimapangidwazo zimakhala ndi zinthu zomwezo monga zida zapita. Chizindikiro chakugwiritsira ntchito kwake ndi kusakwanira kwa chakudya, zolimbitsa thupi ndi monotherapy ndi metformin kapena glibenclamide. Mankhwalawa amangopangidwira odwala okalamba. Kusagwirizana ndi kumwa kungayambitse zovuta zina.
3. Janumet. Wothandizira wophatikiza wa hypoglycemic yemwe phindu lake limachitika chifukwa cha kukhalapo kwa metformin ndi sitagliptin. Amapezeka mu piritsi. Kugwiritsidwa ntchito nokha kapena kuphatikiza ndi mankhwala ena. Amalembera mtundu wachiwiri wa matenda ashuga, koma kuyambira azaka 18 zokha.
4. Amaryl M. Mapiritsi okhala ndi metformin ndi glimepiride. Amawonetsedwa kwa odwala omwe ali ndi matenda ashuga komanso onenepa kwambiri, ngati zoletsa za chakudya sizibweretsa kusintha komwe mukufuna mu thanzi. Kuvomerezedwa kuti mugwiritse ntchito mwa ana ochepera zaka 10.

Asanapange mankhwala, wodwalayo amayenera kukayezetsa, komwe kumapangira molondola njira ya chithandizo.

Ndemanga yakuchepetsa thupi ndi Metformin

Pamabungwe osiyanasiyana azachipatala, mutha kuwerengera ndemanga za anthu omwe asintha kugwiritsa ntchito mankhwalawa kuti athane ndi kunenepa kwambiri. Sitinganene motsimikiza kuti mankhwala a Metformin amathandizanso kubwerera kunenepa kwenikweni.

Ambiri adalephera kuchepetsa thupi mothandizidwa ndi mapiritsi, pomwe odwala nthawi zambiri amawonetsa mawonekedwe oyipa:

Kukumana ndi zizindikiro zosasangalatsa nthawi zambiri kumakwiyitsa odwala, kuwakakamiza kuti ayang'ane njira ina yabwino kwambiri. Koma ziyenera kunenedwa kuti kusowa kwa zotsatira zoyenera chifukwa chogwiritsa ntchito Metformin, nthawi zambiri, kumachitika chifukwa cha kusaphunzira kwa odwala omwe.

Mankhwala a Hypoglycemic Metformin amathandizira kuthana ndi kuchuluka kwamafuta ochulukirapo, makamaka ndi matenda a shuga. Zotsatira zake zimatheka chifukwa cha kuchepa kwa insulin kukana komanso kuchuluka kwa shuga.

Metformin yodziyimira kulemera

Poyamba, mankhwalawa ankangogwiritsidwa ntchito ngati mankhwala antidiabetes. Pambuyo pake, popanga kafukufuku pakati pa akatswiri othamanga komanso omanga thupi, zinaonekeratu kuti Metformin imathandizira kuchepetsa thupi.

Kutsika kowoneka bwino kwamafuta a thupi mukatenga Metformin ndi chifukwa cha zifukwa zingapo. Kudwala kwambiri mosavutikira kumayambitsa kutsika kwa chidwi cha minyewa kupita ku insulin - mahomoni a kapamba, omwe amalimbikitsa kupezeka kwa shuga ndi maselo. Ngati maselo amenewa amayamba kugonjetsedwa, ndiye kuti, insulin, ndiye kuti sangalandire shuga kuchokera m'magazi. Kuti athandize kufooka kwa shuga, kapamba amayamba kupanga insulini yambiri, chifukwa chake, kuphatikiza kwake m'magazi kumakwera.

Zotsatira zake, kuchuluka kwa insulin kumayambitsa kuphwanya njira zonse za thupi. Zomwe zimakhala zosasangalatsa kwambiri kwa anthu omwe amakonda kuzala, metabolid metabolism amasokonezeka, zomwe zikutanthauza kuti mafuta amayamba kuyikiridwa mosavuta, ndipo mapaundi owonjezera amawonekera mofulumira.

Pankhaniyi, kutenga Metformin kuti muchepetse thupi kumawoneka ngati kotheka. Mankhwala amakhudza insulitivity insulin, zomwe zikutanthauza kuti amatha kuichepetsa. Zotsatira zake, kumwa kwa glucose m'maselo kumapangidwira, ndipo kuphatikiza kwakukulu kwa insulin kumakhala kotsekedwa. Zotsatira zake, zimapezeka kuti zimataya mapaundi owonjezera omwe amadanidwa - kulemera kumabwereranso kwakhalidwe labwino.

Kuphatikiza apo, mankhwalawa ali ndi anorexigenic - amathandiza kuchepetsa kulakalaka. Koma ndikofunikira kudziwa kuti si odwala onse omwe amamwa Metformin omwe amadziwa izi, chifukwa amadziwoneka wofooka kwambiri. Chifukwa chake, kutenga Metformin kokha ndikuyembekezera kupondereza chilakolako sichabwino.

Muzochita zamankhwala, Metformin ya mankhwala yochizira kunenepa sikugwiritsidwa ntchito chifukwa cha mwayi wotsika wopeza zotsatira chifukwa cha kuphatikiza kwakukulu.

Kodi Metformin imathandizira kuchepetsa thupi?

Funso lodziwika kwa iwo omwe akufuna kuchepa makilogalamu ndiwotheka ngati zingatheke kuti muchepetse thupi potenga Metformin.

Ngakhale kutchulidwa kochepetsa shuga, Metformin sikuti nthawi zonse amathandizira kuchepetsa thupi. Musaiwale kuti cholinga chake ndi kuchiza matenda a shuga, ndipo ndi matendawa okha omwe ndi othandiza kwambiri. Chifukwa chake, kuchepa thupi kumawonedwa kwambiri odwala matenda ashuga kapena onenepa kwambiri. Chifukwa chake, kutenga Metformin kwa osauka nthawi zambiri sikubweretsa zotsatira zomwe mukufuna.

Kuphatikiza apo, simuyenera kusintha mankhwalawo kukhala mapiritsi amatsenga omwe amachiritsa matendawa popanda kuyesetsa kwa iye mwini. Ngati mukuyang'ana ndemanga za iwo omwe achepetsa thupi, zimapezeka kuti ambiri a iwo adalandira mankhwalawo moyenera ngati mankhwala a shuga, ndipo mapaundi owonjezera omwe atayika anali amodzi mwa zinthu zomwe zidawongolera.

Kuti mankhwalawa adziwike, kudya kwapadera ndikusinthanso kwa moyo wanu wonse ndikofunikira. Ndiye kuti, kuchepa thupi kumatheka popanda Metformin, ndipo mankhwalawa amatha kuchita zinthu zothandizira komanso kusangalatsa kwa njirayo. Zachidziwikire, kupatula milandu pamene kulemera kwambiri kumatsagana ndi matenda a shuga.

Komabe, ngati ndikwabwino m'maganizo kuti muchepetse thupi mukamamwa mapiritsi, pomwe pali kuchuluka kwambiri kwa thupi osowa shuga, muyenera kudziwa momwe mungatenge Metformin molondola kuti musavulaze thanzi lanu.

Malangizo a kumwa mankhwalawa

Patsamba lamasitolo ogulitsa mankhwala mutha kupeza mankhwala ochokera ku Metformin, operekedwa ndi makampani osiyanasiyana, omwe ali ndi ufulu kupereka dzina lawo ku mankhwalawo. Mwachitsanzo, Metformin Teva, Metformin Richter, Metformin Canon, etc. Popeza chinthu chachikulu pazopangidwazo ndi chimodzimodzi, mutha kusankha chilichonse, kapena analogues.

Mukamasankha, mutha kuyendayenda ndi mtengo wa mankhwalawo, ndikusankha yoyenera kwambiri pamtengo. Ndikofunika kulingalira momwe mankhwalawo amapangidwira, chifukwa zomwe zimapangidwira ndizosiyana, ndipo zimatha kuyambitsa zovuta kapena kuyambitsa ziwengo.

Kenako ndikofunikira kudziwa kuchuluka kwa Metformin yomwe imayenera kutengedwa. Mankhwala amapezeka m'mitundu itatu: 500, 850 kapena 1000 mg ya mankhwala othandizira. Ndikulimbikitsidwa kuti ndiyambe ndi mlingo yaying'ono wa 500 mg. Osayesa zolimba kwambiri ndipo nthawi yomweyo yambani kulandira chithandizo ndi Metformin 1000, chifukwa izi zingayambitse zotsatira zoyipa.

Mlingo wa Metformin umakwera pang'onopang'ono, masiku asanu ndi awiri aliwonse pa 500 mg. Mlingo woyenera wovomerezeka ndi 3000 mg patsiku, koma nthawi zambiri amalimbikitsidwa kuti achedwetse mpaka 2000 mg. Kuchulukitsa kuchuluka kwa mankhwalawa kungakhale koopsa, chifukwa kuyambitsa chiwonetsero champhamvu.

Mutha kutenga Metformin nthawi kapena mukatha kudya.

Palinso njira yakumwa mankhwalawa musanagone - ndilolondola, ndipo njirayi ikhoza kutsatira.

Ndemanga za madotolo zamankhwala

Ngati mukuyang'ana kuwunika kwa madotolo, amakayikira kwambiri pakugwiritsa ntchito Metformin pakuchepetsa thupi. Kutsitsa kwa shuga kwa mankhwalawa kumawonekera bwino ndipo amawona onse odwala. Kuphatikiza apo, Metformin imapondaponda ghrelin - mahomoni am'malo a njala, chifukwa chomwe mutha kuyang'anira kudya kwanu komanso kupewa kudya kwambiri. Koma izi sizitanthauza kuti ndizotheka kuchepetsa thupi kokha mothandizidwa ndi mankhwalawa.

Kuphatikiza apo, madokotala amawona kuti mphamvu ya mankhwalawa imasiyanasiyana kutengera wopanga, chifukwa chake sizingakhale chifukwa ichi.

Nthawi zina, madokotala samatsutsa kwenikweni kugwiritsa ntchito Metformin kuti achepetse thupi, koma panthawi imodzimodzi, malangizo amalimbikitsidwa kwa iwo omwe amalemera, kutsatira zomwe zingathandize kupititsa nthawi yochepa kwambiri.

Zingawonekere kuti mumadya zomwe mukufuna mukamachepetsa thupi. M'malo mwake, izi siziri choncho. Mukamatenga Metformin, tikulimbikitsidwa kuti tisinthe kwambiri m'moyo:

1. Masewera olimbitsa thupi amafunikira, chifukwa amathandizira kutumiza kwa glucose m'maselo a minofu.
2. Zakudya zina zimayenera kukhala zopanda zakudya. Choyamba, zonse zotsekemera kwambiri zapamwamba kwambiri, zakudya za ufa zimaletsedwa. Muyenera kuchepetsa kugwiritsa ntchito mafuta ochulukirapo (supuni yamafuta am'madzi siziwerengera). Magawo amafunikanso kuyang'aniridwa.
3. Imwani madzi ambiri, chifukwa amathandizira kuchotsa zinthu zovulaza m'thupi zomwe zimatulutsidwa "pakuwotcha" mafuta owonjezera, motero kupewa kuledzera.
4. Nthawi yakumwa mankhwala ochepetsa thupi pa Metformin sayenera kupitirira masiku 20.

Zoyenera, muyenera kugwiritsa ntchito moyenera kumwa mankhwala ochepetsa thupi. Chithandizo chiyenera kuyang'aniridwa ndi dokotala. Adzakuthandizani kusankha njira yabwino kwambiri komanso mulingo woyenera. Mwachitsanzo, iwo omwe ali onenepa kwambiri amafuna mlingo waukulu kuposa munthu woonda amene amangokhala ndi vuto lotha kunenepa kwambiri komanso amakhala ndi shuga wambiri.

Mwambiri, akatswiri amakhala owopa kwambiri chidwi cha odwala ena omwe alibe matenda ashuga kugwiritsa ntchito Metformin kuti achepetse thupi. Kutsatsa kwina konse komwe mankhwalawa amathandizira kuti achepetse thupi popanda kudya mankhwala a shuga, sikuti ndi njira yotsatsira.

Sizotheka kuti muchepetse thupi mwa kumwa mankhwala okha a Metformin, ndipo nthawi yomweyo muzidya zinthu zovulaza. Kuti mankhwalawa apereke zomwe akufunazo, njira yovuta ndiyofunikira: kuphatikiza zakudya, kudya zolimbitsa thupi ndi kugwiritsa ntchito madzi ambiri.

Koma, kutsatira malangizowa, mutha kupeza zotsatira zabwino popanda kumwa mankhwalawa, omwe, kuwonjezera apo, angayambitse mavuto.

Ndemanga Zamakasitomala a Metformin

Mwa ogula omwe amamwa mapiritsi a Metformin, nawonso ndemanga za 2017 ndizosiyanasiyana. Pakati pawo, pali zabwino.

Kwanthawi yayitali tsopano ndamwa Metformin monga adanenera dokotala. Zotsatira zake zinali zodabwitsa. Amamva bwino, ndipo koposa zonse, iyenso sanazindikire momwe adapopera 5 kg.

Metformin anamwa mankhwala atachira kuchipatala. Kulemera kwatsika mpaka 8 kg! Sindinamvetsetse nthawi yomweyo chifukwa chake, kenako ndidawerenga malangizo a mankhwalawo - zidapezeka kuti Metformin imathandizira kuchepetsa thupi. Kuphatikiza apo, ndinayamba kudya kwambiri, chifukwa chake, mwina zoterezi.

Iwo omwe adachepetsa thupi mothandizidwa ndi Metformin adazindikira kuti mankhwalawa amathandizanso kuchepa mapaundi owonjezera, koma kuti mupeze zotsatira, muyenera kuyesetsa kwambiri ndikukhala ndi chidwi ndi thanzi lanu, makamaka ngati mankhwalawo adagulidwa popanda mankhwala. Kuchepetsa thupi pamaphunziro onse, masiku 20, ndi 10 makilogalamu, koma kuti muchepetse kulemera, zolimbitsa thupi ndikusintha menyu ndikofunikira.

Odwala ena omwe amachepetsa thupi ndi Metformin sanazindikire kusiyana kwakukulu pakutenga Metformin ndi mankhwala ena kuti achepetse thupi. Ubwino wake unali mtengo wa mankhwalawo poyerekeza ndi mtengo wa zakudya zina zothandizira pakudya.

Gulu la odwala omwe adaganiza zochepetsa thupi pogwiritsa ntchito Metformin adalephera kukwaniritsa zotsatira zomwe amafunazo, koma palibe zotsatira zoyipa zomwe zidawonedwa.

Amayi akhala akumwa Metformin Zentiva wa matenda ashuga kwa zaka zingapo. Ndipo china chake kuchepa thupi sichimawonedwa.

Ndemanga zoyipa sizachilendo. Choyamba, iwo omwe adachepetsa thupi sawona kusintha kulikonse pa kulemera. Koma mavuto enanso adawonekera. Odwala ambiri adadandaula za kukhumudwa m'mimba. Nthawi zambiri munthu wonenepa amamutsatira ndi mavuto ena, monga mseru, kufooka, ulesi, alopecia (kutaya kwambiri tsitsi).

Zotsatira zake, titha kunena kuti Metformin, monga mankhwala ena "othandiza kwambiri" kapena zakudya zaposachedwa kwambiri, sizipereka mphamvu, koma zitha kuyambitsa mavuto osiyanasiyana azaumoyo. Simuyenera kugwiritsa ntchito mankhwalawa kukonza vuto lomwe silinakumane nalo.

Momwe Metformin adzafotokozera akatswiri mu kanema munkhaniyi.

Kugwiritsa ntchito metformin pakuchepetsa thupi

Zachidziwikire, metformin ikhoza kugwiritsidwa ntchito pakuchepetsa thupi, koma palibe amene amatsimikizira zotsatirapo zabwino. Mwachitsanzo, Kumbukirani za mzimayi yemwe adayamba kulemera panthawi yomwe amasamba, Pambuyo pake adayamba kumwa metformin kuti achepetse thupi:

“Kukhala mkazi nthawi ya kusamba, ndidachira kwambiri chaka chonse, ndikugwira ntchito kuofesi ya UN ku Afghanistan. Nditamwa metformin mu Mlingo wa 1650 mpaka 2000 mg tsiku lililonse, ndinataya pafupifupi 10 kg m'miyezi isanu ndi umodzi. Ndinadya metformin ndikutsatira zakudya zamagulu ochepa (chifukwa chofunikira). Ndimamwa mankhwalawa ndipo kulemera kwanga kumakhazikika. Kuphatikiza apo, magazi anga atachepa chaka chilichonse kuchokera pa 150/85 mpaka 130/80 popanda mankhwala. Metformin imathandizanso kupewetsa khansa ya m'mawere, chifukwa chake ichi ndi chifukwa chomveka chopitilira. ”

Ndemanga iyi ya mayi yemwe wachepetsa thupi mothandizidwa ndi metformin akhoza kufunsidwa, monga ndemanga zambiri pa intaneti, chifukwa zotheka kuchepa thupi zikadatheka chifukwa chamadyedwe ochepa wama carb, osati chifukwa chogwiritsa ntchito metformin.

Metformin ndi mankhwala osankha zochizira odwala matenda amishuga a 2imagwiritsidwanso ntchito popewa kukula kwa shuga kwa odwala omwe ali ndi prediabetes, omwe amapezeka ndi glycosylated hemoglobin kuyambira 5.7 mpaka 6.4%.

Metformin ndiwofunika kwambiri kwa odwala ambiri omwe ali ndi matenda a shuga a 2 chifukwa chogwira ntchito kwambiri, amatha kukhala ndi vuto la hypoglycemia, zotsatira zoyipa zochepa, kugwiritsa ntchito mosavuta komanso mtengo wotsika. Kuphatikiza apo, metformin imakhala ndi phindu pa kuchepa kwa thupi ndi matenda a shuga a 2, komanso mwina ndi polycystic ovary syndrome (PCOS), komanso kunenepa kwambiri popanda matenda ashuga.

Chizindikiro chachikulu cha kudya metformin ndi mtundu wachiwiri wa matenda ashuga. Chifukwa chake, kumvetsetsa kwazomwe zimachitika ndi metformin pa kuchepa thupi zachitika chifukwa cha kafukufuku wa odwala matenda a shuga 2, m'malo mwa anthu athanzi.

Makina a metformin ndi apadera poyerekeza ndi mankhwala ena ochepetsa shuga.Metformin imachepetsa kupanga kwa shuga m'chiwindi, amachepetsa mayamwidwe m'matumbo, ndikuwongolera kuzindikira kwa insulini pakukulitsa kudya kwa minyewa. Mapiritsi a Metformin amathandizira kuchepetsa kuchepa kwa thupi chifukwa cha kutayika kwa minofu ya adipose, osati chifukwa chogwiritsa ntchito mphamvu zochulukirapo, monga momwe zimakhalira pakuchita zolimbitsa thupi kwambiri.

Metformin imathandizira kuchepetsa kuwonda kwa odwala omwe ali ndi matenda a shuga a 2 komanso polycystic ovary syndrome.

Ngakhale izi, metformin amakhalabe mankhwala osamveka bwino. Maganizo pa sayansi yazachipatala, kuwunika kwa kunenepa pa metformin kumasiyanasiyana, komwe kumafotokozedwera ndi mankhwala omwe amaphunziridwa bwino komanso kusadziwika kwazomwe amachita. Werengani zambiri pa nkhaniyi. Kodi metformin imakhudza bwanji thupi la munthu? Zotsatira zake zoyipa ndi zotsutsana

Mwachitsanzo, mu phunziroli "Potential biomarkers of metformin in activation" (PMCID:PMC4038674) adalemba izi: "Metformin ndiye woyamba kusankha mankhwala osokoneza bongo komanso odwala antidiabetes omwe pano amatengedwa ndi anthu 150 miliyoni padziko lapansi. Zotsatira zazikulu za metformin ndikupewa kupangira shuga mu chiwindi. Komabe palibe wodalirika biomarker adadziwika kuti ayese kuyesa kwa metformin».

Kuyesa kowonjezera kwa sayansi ndikofunikira, makamaka mayeso olamulidwa mosasamala, omwe amafunikira kuti azindikire kutalika ndi kuchuluka kwa metformin ndikuzindikira zotsatira zoyipa zazitali kwa anthu omwe amawalandira popanda matenda a shuga.

Ndemanga pa kutenga metformin kuti muchepetse kunenepa

Nayi mfundo ina kuchokera pa zoyipa kwambiri za kutenga metformin, koma osati yosangalatsa:

"Kumbukirani kuti metformin ikhoza kuyambitsa khosi komanso tsitsi (iyi ndi imodzi mwamavuto azidwala a mankhwalawa), musadabwe tsitsi lanu litayamba kugwa. Kuphatikiza apo, mukamamwa metformin, mutha kuthana ndi zovuta zina ... sindinachepetse thupi ndipo sindimva mphamvu zambiri ndikamamwa metformin. Nditasiya kumwa, Ndinavutika kupuma kwa masiku angapo, chifukwa metformin imachulukitsa mamolekyulu a oxygen omwe amatulutsidwa m'maselo. "

Saar Avr, mkulu wa gulu lankhondo la Israeli (kuwunika koyambirira).

Ndemanga za madokotala zakugwiritsa ntchito metformin pakuchepetsa thupi

Ndemanga zosangalatsa Dr. Bernstein pa Metformin, amakhulupirira kuti metformin imachepetsa njala ndipo sikuti ma fanizo onse a metformin amachitanso chimodzimodzi:

"Kudya kwa Metformin kuli ndi zinthu zina - kumachepetsa matenda a khansa komanso amalepheretsa njala ma ghrelin, potero kuthetsa chizolowezi chakudya kwambiri. Komabe, m'zochitika zanga, si onse mayendedwe of metformin omwe amagwiranso ntchito chimodzimodzi. Nthawi zonse ndimalemba Glucophage, ngakhale kuti ndiokwera mtengo kuposa anzanga ”(Diabetes Soluton, kope 4. P. 249).

Ndipo izi ndi zomwe Elena Malysheva akunena ponena za kugwiritsa ntchito metformin:

Momwe mungatengere metformin mosamala kuti muchepetse thupi? Buku lamalangizo

Ngati mukufunabe kuyesa kutenga Metformin kuti muchepetse kunenepa, zichitike molondola komanso motetezeka.

• Choyamba, khalani okonzekera kuti metformin singayambitse kuchepa kwambiri ndipo mwina singagwire ntchito konse osasintha njira yamoyo yomwe idapangitsa kuti munthu azikhala wonenepa.
• Kachiwiri, pakalandilidwa ndikofunikira kuwunika ntchito ya impso ndi shuga. Kuti muchite izi, muyenera kugula glucometer mu pharmacy ndikuphunzira momwe mungadziyimire nokha shuga. Mutha kutenga miyezo 1-2 kawiri pa sabata. Mungaone kuti nkhaniyi ndi yothandiza: Momwe mungadziyimire nokha popanda magazi ndi glucometer - malangizo. Ntchito ya impso imatha kuwongoleredwa ndi urinalysis, yomwe imayenera kutengedwa nthawi imodzi m'miyezi 3-4.

Kafukufuku wa sayansi pazotsatira za metformin pa kuwonda

Kenako, tikambirana zotsatira za kafukufuku atatu wasayansi wokhudzana ndi kuchepa kwa thupi., Lofalitsidwa pa mbiri yabwino yazachipatala ya PubMed komanso m'magazini yapadera "Nthawi Zamasewera a Bariatric ».

Phunziro 1: "Kugwira ntchito kwa metformin pakuchepetsa thupi mwa anthu onenepa osakhudzana ndi matenda ashuga" (PubMed, PMID: 23147210):

Kuchita kwa metformin pochizira kunenepa kwawunikiridwa m'mayesero osiyanasiyana azachipatala omwe asonyeza zotsatira zosakanikirana. Komanso, kugwiritsa ntchito bwino kwa mankhwalawo pa malo osagulika komanso m'moyo weniweni sichinatsimikizidwebe mpaka pano.

Phunziroli, tinayesa kuwunika momwe metformin imathandizira kukana kwa insulin kwa odwala onenepa komanso onenepa kwambiri.

Tidawachiritsa odwala 154 omwe ali ndi index ya thupi (BMI) ya ≥27 pamiyezi isanu ndi umodzi. Mlingo wa metformin anali 2,500 mg patsiku. Kuphatikiza apo, kuyesako kunakhudza odwala 45 omwe sanamwe mankhwalawa. Kulemera kwa odwala kunayang'aniridwa kwa miyezi 6. Asanayambe chithandizo ndi metformin, zamtundu wa insulin zimayesedwa mwa odwala onse.

Kuchepetsa thupi kwa miyezi isanu ndi umodzi m'magulu a metformin kuchokera pa 5.8 mpaka 7.0 kg. (mwa 5.6-6.5%). Pa gulu osatenga metformin, kulemera kumachepera, pafupifupi, kuyambira 0,8 mpaka 3.5 kg. (0.8-3.7%) Odwala omwe ali ndi insulin kwambiri amakana kutaya kwambiri poyerekeza ndi odwala omwe amalabadira kwambiri insulin. Chiwerengero cha kuchepa thupi sichimadalira zaka, jenda kapena BMI.

Metformin ndi mankhwala othandiza kuti muchepetse kunenepa kwakanthawi kochepa kwa anthu omwe ali ndi vuto la insulin, komanso odwala omwe ali ndi insulin, onenepa kwambiri komanso onenepa kwambiri.

Phunziro 2: "Rosiglitazone ndiyothandiza kwambiri kuposa metformin pakukonza kagayidwe kazakudya kagayidwe kachakudya kwa anthu osaneneka kwambiri odwala matenda ashuga." (PubMed, PMID: 17394563):

Pa phunziroli, odwala omwe alibe odwala matenda ashuga azaka za 18-65 komanso mndandanda wazovuta kwambiri wazaka 35-50 adasankhidwa. Zotsatira zamankhwala omwe amachitika pakadutsa miyezi 6 ndi metformin (850 mg., Kawiri pa tsiku) kapena rosiglitazone (4 mg., Kawiri pa tsiku) pakusintha kotheka kulemera kwa thupi, mafuta m'thupi, shuga wamagazi ndi lipid metabolism adaphunzira.

Kuchepetsa kwakukulu ndi kuchepa kwamafuta amthupi adapezeka atatenga metformin (-9.7 +/- 1.8 kg ndi -6.6 +/- 1.1 kg), komanso rosiglitazone (-11.0 +/- 1.9 kg ndi -7.2 +/- 1.8 kg) pagulu lililonse la maphunziro.

Odwala omwe amatenga mapiritsi a rosiglitazone, kuchepa kwakukulu kwa shuga m'magazi ndi insulin kunawonedwa, komanso kuwonjezeka kwa insulin sensitivity. Mosiyana ndi izi, metformin inalibe gawo lalikulu pamagetsi a shuga, magazi, insulin, ndi index ya kukana insulin. Panalibe zotsatila mutamwa mankhwalawa.

Kafukufuku wathu akuwonetsa kuti kwa odwala omwe ali ndi kunenepa kwambiri, omwe alibe shuga, komanso hyperinsulinism, rosiglitazone imakhala yothandiza kwambiri kuposa metformin, yomwe imatsimikiziridwa ndikusintha koyenera malinga ndi zizindikiro za metabolism, kuchepa kwa insulin kukokana ndi hyperinsulinemia. Ngakhale maphunziro am'mbuyomu omwe adanenedwa kuti adawonjezera kulemera atatha kutenga Rosiglitazone, pakuphunzira kwathu kuphatikiza chithandizo ndi zakudya ndipo Rosiglitazone idatsatana ndi kuchepa kwa thupi komanso kuchepa kwamafuta m'maphunziro ambiri.

Kafukufuku 3. “Kukana kwa insulini komanso kugwiritsa ntchito metformin: kuthana ndi thupi” (lofalitsidwa mu magazini yamankhwala Nthawi za Bariatric. 2011, 8(1):10–12).

Anazindikira kuti metformin ndi mankhwala ogwiritsidwa ntchito kwambiri pochiza matenda ashuga komanso prediabetes, metabolic syndrome ndi insulin. Nthawi yomweyo, kupewa matenda ashuga Kudya kwa Metformin sikunali kothandiza monga mtundu wanthawi zonse - moyo ukusintha.

Metformin imakhaladi mwala wofunika kwambiri wa mankhwala a shuga ndipo nthawi zambiri imagwiritsidwa ntchito ngati kusankha koyamba. Mwambiri, metformin ndi mankhwala osagwirizana nawo pazokhudza kulemera kwa thupi, ndikuwonetsa umboni wina wakuchepetsa thupi. Metformin imawoneka kuti imachepetsa kulemera, zomwe zimayambitsidwa ndi othandizira ena omwe amagwiritsidwa ntchito pochiza matenda a shuga.

Nthawi yomweyo Kugwiritsa ntchito metformin monga gawo lalikulu pakuchepetsa thupi kwa anthu opanda matenda ashuga kumawoneka osayenera kwa anthu ambiri. Kupatula pa lamuloli kungakhale azimayi omwe ali ndi polycystic ovary syndrome (PCOS).

Chidule:

1. Metformin si malo opepuka kuwonda. Mwina mankhwalawa siabwino kwa inu, koma kudya komanso kuchita masewera olimbitsa thupi ndizopatsa zipatso zambiri.
2. Kafukufuku akuwonetsa kuti mapiritsi a metformin amatha kugwiritsidwa ntchito pakuchepetsa thupi, ngakhale kuti zotsatira zake ndizosafunikira kapena mwina sizingakhalepo chifukwa cha zinthu zina zomwe zimakhudza kuchepa kwa thupi.
3. Kuchepetsa thupi ndi metformin ndikofunikira mwanzeru. Ndikulimbikitsidwa kuti muyeze miyezo ya shuga ya kunyumba kunyumba kawiri pa sabata, komanso mumayesere mkodzo pafupipafupi ndi miyezi 2-4 kuti muwone momwe ntchito ya impso ikuyendera.

Zotsatira Zosavuta

Chiyeso china chofunikira chachipatala chotchedwa British Prospective Diabetes Study (UKPDS) chidachitika mwa anthu odwala matenda ashuga a 2 omwe anali onenepa kwambiri komanso omwe ankamwa metformin. Zotsatira:

• kufa kwa matenda ashuga a 2 amachepetsa ndi 42%,
• wochepetsedwa chiopsezo cha zotumphukira - 32%,
• chiopsezo cha myocardial infarction chimachepetsedwa ndi 39%, stroke - 41%,
• kufa kwathunthu kumachepetsedwa ndi 36%.

Kafukufuku waposachedwa, Dongosolo la Chitetezo cha Matenda a shuga, adachitidwa pa mankhwala oyamba aku France, Glucofage. Pambuyo pake, mawu otsatirawa adatinso:

• kuchepa kapena kuletsa kukula kwa matenda ashuga mwa anthu omwe ali ndi vuto la chakudya m'thupi ndi 31% adadziwika.

Zambiri za mankhwala ochepetsa thupi komanso mankhwalawa a matenda a shuga 2

Zodziwika kwambiri komanso zabwino kwambiri ndi izi: Glucophage (mankhwala oyambirira achi French), Metformin yopangidwa ndi Gideon Richter ndi Siofor. Kusiyana pakati pawo sikokulira, zinthu zomwe zimagwiritsidwa ntchito ndizofanana, zokhazokha zothandizirana zimatha kukhala zosiyana zomwe zimakhudza kumasulidwa ndi kuperewera kwa mankhwalawo pawokha m'thupi.

Mankhwala otchuka omwe ali ndi "metformin" yogwira ntchito, mtengo wake umatengera mlingo:

GlucophageMerck Sante, FranceKuyambira 163 mpaka 310 Metformin RichterGideon Richter-Rus, RussiaKuyambira 207 mpaka 270 SioforBerlin Chemie, Germany258 mpaka 467

Ma analogi a Metformin

Mankhwala ena ochepetsa thupi komanso mankhwalawa a matenda a shuga 2:

Ndemanga yakuchepetsa thupi komanso odwala matenda ashuga

Inna, wazaka 39: Ndili ndi mapaundi owonjezera komanso matenda ashuga a 2. Dotolo adatchulira metformin ndikuti amathandizanso kuonda. Poyamba sindinazikhulupirire, chifukwa ngakhale kudya komanso kuchita masewera olimbitsa thupi sizinathandize. Koma popeza mankhwalawo anali oyamba a matenda ashuga, ndidaganiza zondiyamwa choncho, kutsatira zomwe adandipatsa poyambira zakudya. Ndinadabwa kwambiri mwezi umodzi pambuyo pake nditawona pamiyeso yochepera kuposa masiku onse.

Ivan, wazaka 28: M'moyo wanga wonse ndakhala wonenepa: shuga ndi wabwinobwino, masewera alipo, ndimangodya chakudya - palibe chomwe chimagwira. Ndinayesa mankhwala osiyanasiyana ochepetsa thupi, kuphatikizapo metformin. Kuphatikiza pa kudzimbidwa, sindinalandire chilichonse, kulemera kwake kunakulanso chimodzimodzi ngati wopanda iye. Zingakhale kuti adatenga popanda mankhwala a dokotala ndikusankha mulingo woyenera.

Metformin ndi chida chapadera chochepetsera kunenepa komanso kuthana ndi matenda a shuga a 2, musadzitengere nokha. Kuphatikiza apo, amamugawa ndi mankhwala, omwe amapereka kuchuluka kwa kuchuluka ndi kuvomerezeka. Kudzipatsa nokha mankhwala kukhala koopsa ku thanzi!