HUMALOG 100ME

Ngakhale kuti asayansi adakwanitsa kubwereza molekyulu yonse ya insulin, yomwe imapangidwa m'thupi la munthu, zochita za mahomoniwo zidasinthiratu chifukwa nthawi yomwe amafunika kunyamula magazi. Mankhwala oyamba osinthika anali insulin Humalog. Imayamba kugwira ntchito patangodutsa mphindi 15 jakisoni, choncho shuga yochokera m'mwaziyo imasamutsidwira minofu yake munthawi yake, ndipo ngakhale hyperglycemia yochepa siyimachitika.

Poyerekeza ndi ma insulins omwe adapangidwa kale, Humalog ikuwonetsa zotsatira zabwino: mwa odwala, kusinthasintha kwa shuga tsiku ndi tsiku kumachepetsedwa ndi 22%, mawonekedwe a glycemic amayenda bwino, makamaka masana, ndipo mwayi wa kuchepa kwambiri kwa hypoglycemia umachepa. Chifukwa chachangu, koma chokhazikika, insulin iyi imagwiritsidwa ntchito kwambiri mu shuga.

Malangizo achidule

Malangizo ogwiritsira ntchito insulin Humalog ndiwosakhazikika, ndipo magawo omwe amafotokoza zoyipa ndi mayendedwe akugwiritsidwa ntchito amakhala ndi zigawo zingapo. Kufotokozera kwakutali komwe kumayendera limodzi ndimankhwala ena kumadziwika ndi odwala ngati chenjezo lokhuza kuwopsa kwawo. M'malo mwake, zonse ndizofanana: langizo lalikulu, latsatanetsatane - umboni wa mayesero ambirikuti mankhwalawa adapirira.

Humalogue wavomerezedwa kuti agwiritse ntchito zaka 20 zapitazo, ndipo tsopano sizabwino kunena kuti insuliniyi ndi yotetezeka pa mlingo woyenera. Imavomerezedwa kuti agwiritsidwe ntchito ndi onse akulu ndi ana; itha kugwiritsidwa ntchito pazochitika zonse zomwe zimaphatikizidwa ndi kuperewera kwamahomoni akulu: mtundu 1 ndi matenda ashuga a 2, shuga ya gestational, ndi opaleshoni ya pancreatic.

Zambiri pa Humalogue:

Zina mwazotsatira zoyipa, hypoglycemia ndi thupi lawo siligwirizana nthawi zambiri zimawonedwa (1-10% ya odwala matenda ashuga). Osakwana 1% odwala amakhala ndi lipodystrophy pamalo opangira jekeseni. Makulidwe azinthu zina zoyipa amakhala ochepera 0.1%.

Chofunika Kwambiri Zokhudza Humalog

Kunyumba, Humalog imayendetsedwa pang'onopang'ono pogwiritsa ntchito cholembera kapena pampu ya insulin. Ngati matenda oopsa a hyperglycemia atachotsedwa, mankhwala osokoneza bongo amathandizanso kuchipatala. Pankhaniyi, kuthana ndi shuga pafupipafupi ndikofunikira kupewa bongo.

Chithandizo chogwira ntchito cha mankhwala ndi insulin lispro. Amasiyana ndi mahomoni amunthu pakupanga ma amino acid mu molekyulu. Kusintha koteroko sikulepheretsa ma cell receptors kuzindikira mahomoni, chifukwa chake amapatsira shuga mwa iwo okha. Chiwonetserochi chimakhala ndi ma insulin monomers okha - mamolekyulu osalumikizana. Chifukwa cha izi, imakamizidwa mwachangu komanso moyenera, imayamba kuchepetsa shuga mwachangu kuposa insulin yachilendo.

Humalog ndi mankhwala ofupikitsika kuposa, mwachitsanzo, Humulin kapena Actrapid. Malinga ndi gulu, amatchulidwa ndi ma insulin omwe ali ndi ultrashort action. Kuyamba kwa ntchito yake kumachitika mwachangu, pafupifupi mphindi 15, kotero odwala matenda ashuga sayenera kudikirira mpaka mankhwalawo atagwira, koma mutha kukonzekera chakudya mukangobaya jakisoni. Chifukwa cha kufupika kwakanthawi, kumakhala kosavuta kukonza zakudya, ndipo chiopsezo cha kuiwala chakudya jakisoni itachepa.

Kuti muthane ndi vuto labwino la glycemic, insulin yothamanga iyenera kuphatikizidwa ndi kuvomerezedwa kwa insulin yayitali. Chokha chosiyana ndi kugwiritsa ntchito pampu ya insulin nthawi zonse.

Sankhani

Mlingo wa Humalog umatengera zinthu zambiri ndipo umatsimikiziridwa payekhapayekha kwa aliyense wodwala matenda ashuga. Kugwiritsa ntchito njira zoyenera sikulimbikitsidwa, popeza zimakulitsa kubwezeretsanso shuga. Ngati wodwala amatsatira zakudya zamafuta ochepa, mlingo wa Humalog umakhala wocheperako kuposa momwe oyang'anira angapangire. Pankhaniyi, tikulimbikitsidwa kugwiritsa ntchito insulin yofulumira.

Hormashort ya Ultrashort imapereka mphamvu kwambiri. Mukasinthira ku Humalog, mlingo wake woyambirira amawerengedwa ngati 40% ya insulin yayifupi. Malinga ndi zotsatira za glycemia, mlingo umasinthidwa. Chofunikira pakukonzekera mkate uliwonse ndimagawo 1-1,5.

Ndondomeko ya jekeseni

Chakudya chimayalidwa chakudya chilichonse chisanachitike. osachepera katatu patsiku. Pankhani ya shuga wambiri, mawonekedwe okhathamira pakati pa jakisoni wamkulu amaloledwa. Malangizo ogwiritsira ntchito akutsimikizira kuwerengera kuchuluka kwa insulini yochokera pamafuta omwe akukonzekera chakudya chotsatira. Pafupifupi mphindi 15 ayenera kuchokera jakisoni kupita chakudya.

Malinga ndi ndemanga, nthawi ino nthawi zambiri zimakhala zochepa, makamaka masana, pomwe insulin kukana imakhala yotsika. Mlingo wa mayamwidwe ndi munthu payekhapayekha, umatha kuwerengeka pogwiritsa ntchito kuchuluka kwa shuga m'magazi pambuyo pobayidwa. Ngati kutsitsa kwa shuga kumawonedwa mwachangu kuposa momwe malangizowo amafunikira, nthawi yomwe chakudya chisanachitike iyenera kuchepetsedwa.

Humalog ndi imodzi mwamankhwala omwe amafulumira kwambiri, motero ndikosavuta kugwiritsa ntchito ngati thandizo ladzidzidzi la matenda ashuga ngati wodwala akuwopseza kuti ali ndi vuto la hyperglycemic.

Nthawi yogwira (yochepa kapena yayitali)

Peak ya insulin ya ultrashort imawonedwa patatha mphindi 60 kuchokera pakukhazikitsa. Kutalika kwa zochita zimatengera mlingo; kukula kwake ndikutalika kwa shuga, pafupifupi maola pafupifupi anayi.

Kusakaniza kwa Humalog 25

Kuti muwone molondola momwe Humalog ikuyendera, glucose amayenera kuyesedwa pambuyo pa nthawi imeneyi, nthawi zambiri izi zimachitidwa chakudya chotsatira chisanachitike. Miyeso yoyambirira imafunikira ngati hypoglycemia ikukayikira.

Kutalika kwakanthawi kwa Humalog si koyipa, koma mwayi wa mankhwalawa. Tikuthokoza, odwala omwe ali ndi matenda osokoneza bongo sakhala ndi vuto la hypoglycemia, makamaka usiku.

Doctor of Medical Science, Mutu wa Institute of Diabetesology - Tatyana Yakovleva

Ndakhala ndikuphunzira matenda a shuga kwa zaka zambiri. Zimakhala zowopsa anthu ambiri akamwalira, ndipo makamaka amakhala olumala chifukwa cha matenda ashuga.

Ndithamangira kunena mbiri yabwino - Endocrinological Research Center ya Russian Academy of Medical Sayansi yakwanitsa kupanga mankhwala omwe amachiritsa odwala matenda ashuga mellitus. Pakadali pano, kugwiritsa ntchito bwino kwa mankhwalawa kuyandikira 98%.

Nkhani ina yabwino: Unduna wa Zaumoyo wateteza kukhazikitsidwa kwa pulogalamu yapadera yomwe imalipira mtengo wa mankhwalawo. Ku Russia, odwala matenda ashuga mpaka Meyi 18 (kuphatikiza) nditha kuipeza - Kwa ma ruble 147 okha!

Kusakaniza Kwa Humalog

Kuphatikiza pa Humalog, kampani yopanga zamankhwala Lilly France imatulutsa Humalog Remix. Ndiosakanikirana kwa lyspro insulin ndi protamine sulfate. Chifukwa cha kuphatikiza uku, nthawi yoyambira ya mahomoni imakhalabe mwachangu, ndipo nthawi yochitapo kanthu imawonjezeka kwambiri.

Kusintha kwa Humalog kumapezeka mu 2indi:

Ubwino wokhawo wa mankhwalawa ndi regimen yosavuta. Kulipira shuga kwa odwala matenda ashuga ndi kagwiritsidwe ntchito kwawo ndi koipa kuposa kukhala ndi mankhwalawa a insulin komanso kugwiritsa ntchito mtundu wina wa Humalog ana Humalog Mix sagwiritsidwa ntchito.

Insulin iyi imayikidwa:

1. Anthu odwala matenda ashuga omwe sangathe kuwerengera payekha payekha kapena kupanga jakisoni, mwachitsanzo, chifukwa cha kusawona bwino, ziwalo kapena kugwedezeka.
2. Odwala omwe ali ndi matenda amisala.
3. Okalamba okalamba omwe ali ndi zovuta zambiri za matenda a shuga komanso kuperewera koyipa kwa chithandizo ngati safuna kuphunzira malamulo owerengera insulin.
4. Anthu odwala matenda ashuga omwe ali ndi matenda amtundu wa 2, ngati mahomoni awo akupangidwabe.

Kuchiza matenda a shuga ndi Humalog Remix kumafuna kudya mosasangalatsa yunifolomu, zokhwasula-khwasula pakati pa chakudya. Amaloledwa kudya mpaka 3 XE pa chakudya cham'mawa, mpaka 4 XE pachakudya chamadzulo komanso chamadzulo, pafupifupi 2 XE pachakudya chamadzulo, ndi 4 XE asanagone.

Ma Analogi a Humalog

Lyspro insulin monga chinthu chogwira imangopezeka mu Humalog yoyambayo. Mankhwala osokoneza bongo ndi NovoRapid (kutengera aspart) ndi Apidra (glulisin). Zida izi ndizoperewera -fupi, choncho zilibe kanthu kuti muzisankha iti. Zonse zimalekeredwa bwino ndipo zimapereka shuga msanga. Monga lamulo, zokonda zimaperekedwa kwa mankhwalawa, omwe amatha kupezeka kwaulere kuchipatala.

Kusintha kuchokera ku Humalog kupita ku analogue yake kungakhale kofunikira pakakhala zovuta zina. Ngati wodwala matenda ashuga amatsatira zakudya zamafuta ochepa, kapena amakhala ndi hypoglycemia, ndizosavuta kugwiritsa ntchito anthu m'malo mwa insulin.

Onetsetsani kuti mwaphunzira! Kodi mukuganiza kuti kuyamwa kwa mapiritsi ndi insulini kwa nthawi yonse yokhayo ndi njira yokhayo yothanirana ndi shuga? Sichowona! Mutha kutsimikizira izi nokha ndikuyamba kuzigwiritsa ntchito. werengani zambiri >>

Mlingo

Katemera, wowoneka bwino, wopanda utoto

insulin lispro 100 IU

Othandizira: glycerol (glycerin), zinc oxide (zinc oxide), sodium hydrogen phosphate (dibasic sodium phosphate), metacresol, madzi am'madzi, hydrochloric acid (10% yankho) ndi sodium hydroxide (10% yankho) (kukhazikitsa pH) .

Mlingo wa mankhwala

Mlingo weniweni wa mankhwalawa umatsimikiziridwa payekhapayekha ndi dokotala wopezekapo, chifukwa zimatengera momwe wodwalayo alili.

Nthawi zambiri amalimbikitsidwa kugwiritsa ntchito mankhwalawa musanadye, komabe, ngati kuli koyenera, angathe kumwedwa mutatha kudya.

Humalog 25 imayendetsedwa makamaka mosazindikira, koma nthawi zina njira yolowerera imatheka.

Kubweretsa yankho kuyenera kuchitika mosamala kwambiri, chifukwa mutha kulowa mosavuta m'mitsempha yamagazi. Pambuyo pakuchita bwino, sikuloledwa kutikita minofu pamalo a jekeseni.

Kutalika kwa chochita kumatengera zinthu zingapo. Kuchokera pa mlingo womwe wagwiritsidwa ntchito, komanso malo opaka jakisoni, kutentha kwa thupi la wodwalayo komanso zochitika zina zolimbitsa thupi.

Makulidwe a insulin ndi amodzi payekha.

Mlingo wa mankhwala a Humalog 50 umatsimikizidwanso payekha ndi adotolo, kutengera kuchuluka kwa shuga m'magazi.

Jakisoni amaperekedwa kokha m'mitsempha, m'chiuno, ntchafu, kapena pamimba.

Kugwiritsa ntchito mankhwalawa kwa jakisoni wovomerezeka sikovomerezeka.

Pambuyo pakuwona mlingo woyenera, tsamba la jakisoni liyenera kusinthidwa kuti linagwiritsidwe osatinso kamodzi masiku 30.

Mtengo mumafakitale aku Russia:

• Sakanizani kuyimitsidwa kwa 25 kwa jakisoni 100 IU / ml 5 zidutswa - kuchokera ku 1734 rubles,
• Sakanizani kuyimitsidwa kwa 50 kwa jakisoni 100 IU / ml 5 zidutswa - kuchokera ku ma ruble a 1853.

Matenda a shuga amawopa mankhwalawa, ngati moto!

Muyenera kungolemba ...

Chidziwitso chonse cha mankhwalawa Humalog mu kanema:

Humalog imagwiritsidwa ntchito ndi odwala matenda ashuga kusintha matenda a shuga. Ndizowonetsera mwachindunji cha insulin ya anthu. Zimapangidwa ku France monga njira yothetsera yankho ndi kuyimitsa jakisoni. Contraindicated ntchito ndi hypoglycemia ndi tsankho kwa zigawo zikuluzikulu za mankhwala.

Mankhwala

DNA imabweretsanso insulin. Amasiyana ndi omaliza mwanjira zotsatizana za amino acid pamalo 28 ndi 29 a insulin B.

Choyambitsa chachikulu cha mankhwalawa ndi kuyamwa kwa kagayidwe kazakudya. Kuphatikiza apo, ili ndi anabolic zotsatira. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogeneis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.

Odwala omwe ali ndi mtundu woyamba wa 2 ndi mtundu wa 2 shuga, akamagwiritsa ntchito insulin lyspro, hyperglycemia yomwe imachitika chakudya itatha amachepetsa kwambiri poyerekeza ndi insulin yaumunthu. Kwa odwala omwe amalandira ma insulin achidule komanso ofunika, amafunika kusankha kuchuluka kwa ma insulin onse kuti tsiku lililonse azikhala ndi shuga.

Monga momwe akukonzekera insulin yonse, kutalika kwa nthawi ya lyspro insulin kumatha kukhala kosiyanasiyana mwa odwala kapena nthawi zosiyanasiyana wodwala yemweyo ndipo zimatengera mlingo, malo a jakisoni, magazi, kutentha kwa thupi ndi zochitika zolimbitsa thupi.

Mankhwala a lyspro insulin mwa ana ndi achinyamata ali ofanana ndi omwe amawonekera mwa akulu.

Odwala omwe ali ndi matenda a shuga a mtundu wachiwiri amalandila Mlingo wambiri wa sulfonylurea, kuwonjezera kwa insulin kumapangitsa kuchepa kwa hemoglobin wa glycated.

Mankhwala a Lyspro insulin odwala omwe ali ndi vuto la mtundu woyamba 1 komanso 2 amaperekedwera limodzi ndi kuchepa kwa ziwopsezo za nocturnal hypoglycemia.

Kuyankha kwa glucodynamic ku isulin lispro sikudalira kugwira ntchito kwa impso kapena chiwindi.

Lyspro insulin yawonetsedwa kuti imakhala yofanana ndi insulin yaumunthu, koma zochita zake zimachitika mwachangu kwambiri ndikukhalitsa kwakanthawi.

Lyspro insulin imadziwika ndi kuyamba mwachangu (pafupifupi mphindi 15), monga Ili ndi mayamwidwe ambiri, ndipo izi zimakupatsani mwayi woti mulowe musanadye (0-15 mphindi musanadye), mosiyana ndi insulin yachilendo (mphindi 30-45 musanadye). Lyspro insulin imakhala ndi nthawi yofupikirako (maola 2 mpaka 5) poyerekeza ndi insulin yaumunthu wamba.

Gulu la Nosological (ICD-10)

Mlingo ndi makonzedwe

P / C mwanjira ya jakisoni kapena kulowetsedwa kwa sc ndi pampu ya insulin.

Mlingo wa Humalog ® umatsimikiziridwa ndi dokotala aliyense payekha, kutengera kuchuluka kwa shuga m'magazi. Ndondomeko ya insulin makonzedwe ali payekha. Humalog ® imatha kuperekedweratu chakudya chisanafike, ngati kuli koyenera, chitha kuperekedwera pambuyo chakudya. Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Ngati ndi kotheka (ketoacidosis, matenda owopsa, nthawi pakati pa ntchito kapena nthawi yothandizira), mankhwalawa Humalog ® amathanso kutumikiridwa iv.

SC iyenera kuperekedwa kwa phewa, ntchafu, matako, kapena pamimba. Masamba a jakisoni amayenera kusinthidwa kuti malo omwewo asagwiritsidwerenso kuposa nthawi 1 pamwezi.

Mukamayambitsa mankhwala a Humalog ® pakukhazikitsidwa, chisamaliro chiyenera kutengedwa kuti mupewe magazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Wodwala ayenera kuphunzitsidwa njira yolondola ya jakisoni.

Kukonzekera kukhazikitsa kwa Humalog ® m'makalata

Yankho la Humalog ® liyenera kukhala lomveka komanso lopanda utoto. Osagwiritsa ntchito yankho la kukonzekera kwa Humalog ® ngati kudzakhala mitambo, makulidwe, utoto wopanda mphamvu, kapena tinthu tating'onoting'ono tadziwika. Mukakhazikitsa cartridge mu syringe cholembera, ndikukhala ndi singano ndikulowetsa insulin, tsatirani malangizo a wopanga omwe akuphatikizidwa ndi cholembera chilichonse.

2. Sankhani tsamba la jakisoni.

3. Konzani khungu lanu jakisoni monga momwe adokotala akulimbikitsira.

4. Chotsani kapu yodzitchinjiriza kunja kwa singano.

5. Konzani khungu.

6. Ikani singano ya SC ndikuchita jakisoni molingana ndi malangizo ogwiritsira ntchito cholembera.

7. Chotsani singano ndikufinya pang'onopang'ono malo opaka jakisoni ndi swab ya thonje kwa masekondi angapo. Osatupa malo a jakisoni.

8. Pogwiritsa ntchito singano yodzitchinjiriza ya singano, iduleni ndikuitaya.

9. Ikani chipewa pa cholembera.

Mu / pakubweretsa insulin. Kubayidwa kwapakati pa Humalog ® kukonzekera kuyenera kuchitika molingana ndi chizolowezi chachipatala cha jakisoni wamkati, mwachitsanzo pakukonzekera kwa bolus kapena kugwiritsa ntchito kulowetsedwa. Poterepa, nthawi zambiri ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi. Makina a kulowetsedwa ndi zozungulira kuchokera ku 0,1 mpaka 1 IU / ml insulin lispro mu 0,9% sodium chloride solution kapena 5% dextrose yokhazikika ndi kutentha kwa chipinda kwa maola 48.

P / c insulin kulowetsedwa pogwiritsa ntchito insulin pump. Potengera kukonzekera kwa Humalog ®, mapampu angagwiritsidwe ntchito - makina opitilira sc insulin ya insulin yokhala ndi chizindikilo cha CE. Musanagwiritse inshuwaransi ya lyspro, onetsetsani kuti pampu ina ndiyabwino. Muyenera kutsatira mosamalitsa malangizo omwe abwera ndi pampu. Gwiritsani ntchito chosungira chokha ndi patheter pampu. The kulowetsedwa anayenera asinthidwe malinga ndi malangizo omwe amaperekedwa ndi kulowetsedwa. Ngati vuto la hypoglycemic litayamba, kulowetsaku kumayimitsidwa mpaka gawo litatsimikiza. Ngati shuga wambiri m'magazi adziwika, ndikofunikira kudziwitsa dokotala za izi ndikupereka kuchepa kapena kufooka kwa kulowetsedwa kwa insulin. Kuperewera bwino kwa pampu kapena kufalikira mu dongosolo la kulowetsedwa kungapangitse kukwera kwamphamvu kwa glucose. Ngati mukukayikira kuti ndikuphwanya kupereka kwa insulin, muyenera kutsatira malangizowo ndipo ngati kuli koyenera dziwitsani adokotala. Mukamagwiritsa ntchito pampu, kukonzekera kwa Humalog ® sikuyenera kusakanikirana ndi ma insulini ena.

Pokonzekera Humalog ® mu cholembera cha syPinge ya QuickPen, ndikofunikira kuti muzolowere cholembera cha QuickKen ™ musanapereke insulin.

QuickPen ™ Humalog® 100 IU / ml, 3 ml Syringe chole

Nthawi iliyonse mukalandira phukusi latsopano ndi zolembera za syPinge za QuickPen, muyenera kuwerenga malangizo kuti mugwiritsirenso, monga ikhoza kukhala ndi zidziwitso zosinthidwa. Zomwe zili m'malamulowa sizilowa m'malo ndi zokambirana ndi dokotala za matenda komanso chithandizo cha wodwala.

Chikwangwani cha QuickPen ™ Syringe ndi cholembera choti chitha kutayika, chomwe chili ndi zigawo 300 za insulin. Ndi cholembera chimodzi, wodwala amatha kuperekera insulin zingapo. Pogwiritsa ntchito cholembera ichi, mutha kulowa muyezo ndi chidziwitso cha 1 unit. Mutha kulowa kuchokera pa 1 mpaka 60 mayunitsi paliponse. Ngati mlingo upambana 60 mayunitsi, jekeseni woposa mmodzi adzafunika. Ndi jakisoni aliyense, pisitoni imangoyenda pang'ono, ndipo wodwalayo sangathe kuwona kusintha kwake. Piston imafika pansi pa cartridge pokhapokha wodwala atamaliza kuyika mayunitsi onse 300 omwe ali mu cholembera.

Cholembera sichitha kugawidwa ndi anthu ena, ngakhale mutagwiritsa ntchito singano yatsopano. Osagwiritsanso ntchito singano. Osapatsira singano kwa anthu ena - matenda atha kupatsirana ndi singano, omwe angayambitse matenda.

Simalimbikitsidwa kwa odwala omwe ali ndi vuto losawona bwino kapena kuwonongeka kwathunthu popanda thandizo la anthu odziwa bwino omwe amaphunzitsidwa bwino kugwiritsa ntchito cholembera.

Cholembera cha syringe cha QuickPen ™ Humalog ® chimakhala ndi mtundu wamtambo wabuluu, batani la burgundy ndi cholembera choyera chokhala ndi bala la burgundy.

Kuti mugwiritse ntchito jakisoni, mumafunika cholembera cha QuickPen ™ ndi insulini, singano yolumikizana ndi cholembera cha syringe ya QuickPen ™ (tikulimbikitsidwa kugwiritsa ntchito zolembera za syringe Becton, Dickinson ndi Company (BD), ndi swab choviikidwa mu mowa.

Kukonzekera kwa insulin

- Sambani m'manja ndi sopo,

- Yang'anani cholembera kuti isakhale ndi mtundu wabwino wa insulini. Izi ndizofunikira kwambiri ngati wodwala agwiritsa ntchito mtundu umodzi wa insulin,

- osagwiritsa ntchito zolembera zomwe zatha pa labu,

- Pakhungu lililonse, gwiritsani ntchito singano yatsopano popewa matenda ndikupewera singano.

Gawo 1 Chotsani kapu ya cholembera (osachotsa cholembera) ndikupukutira disc ndi mphira womira mu mowa.

Gawo 2. Onani mawonekedwe a insulini. Humalog ® iyenera kukhala yowonekera komanso yopanda utoto. Osagwiritsa ntchito ngati ndi mitambo, ali ndi utoto, kapena tinthu tating'onoting'ono kapena mawonekedwe.

Gawo 3. Tengani singano yatsopano. Chotsani chomata papepala lakunja kwa singano.

Gawo 4. Ikani kapu ndi singano mwachindunji pa cholembera ndipo mutembenukire singano ndi kapu mpaka itagundika.

Gawo 5. Chotsani thumba lakunja la singano, koma osalitaya. Chotsani thumba lamkati la singano ndikuitaya.

Kuyang'ana cholembera kuti mugwiritse ntchito mankhwala osokoneza bongo

Kuyendera kotereku kuyenera kuchitika usanalowe jekeseni aliyense.

Kuyang'ana cholembera kuti mupeze mankhwala osokoneza bongo kumachitika kuti muchotse mpweya mu singano ndi cartridge, yomwe imatha kudziunjikira nthawi yayitali, ndikuonetsetsa kuti cholembera chikugwirira ntchito moyenera.

Ngati simupanga cheke chotere musanalowe jekeseni iliyonse, mutha kulowa insulin yotsika kwambiri kapena kwambiri.

Gawo 6. Kuti mupeze zolembera zama syringe pakumwa mankhwala, zigawo ziwiri ziyenera kukhazikitsidwa ndikusintha batani la mlingo.

Gawo 7. Gwirani cholembera ndi singano m'mwamba. Dinani mopepuka chokolembera kuti thovu la mlengalenga lithe pamwamba.

Gawo 8. Pitilizani kugwira cholembera ndi singano mmwamba. Kanikizani jakisoni wa jekeseni wa mankhwala mpaka atayima ndipo "0" awonekere pazenera. Mukugwira batani la mlingo, pang'onopang'ono muwerengereni 5. Insulini iyenera kuwonekera pamphumi ya singano.

- Ngati dontho la insulin silikupezeka kumapeto kwa singano, bwerezaninso zomwe mungachite kuti mupeze cholembera kuti mupeze mankhwala osokoneza bongo. Cheke chitha kuchitidwa osapitilira kanayi.

- Ngati insulini siyinatuluke, sinthani singano ndikubwereza cheke cholembera mankhwalawo.

Kukhalapo kwa thovu laling'ono labwinobwino nkwachibadwa ndipo sikukhudza mlingo womwe umaperekedwa.

Mutha kulowa kuchokera pa 1 mpaka 60 mayunitsi paliponse. Ngati mlingo upambana 60 mayunitsi, jekeseni woposa mmodzi adzafunika.

Ngati mukufuna thandizo la momwe mungagawere bwino mankhwalawa, muyenera kulankhulana ndi dokotala.

Pakupukusika kulikonse, singano yatsopano iyenera kugwiritsidwa ntchito ndipo njira yofufuzira cholembera kuti mupeze mankhwala osokoneza bongo iyenera kubwerezedwa.

Gawo 9. Kuti muziyimba kuchuluka kwa insulini, tembenuzani batani la mlingo. Chizindikiro cha mlingo uyenera kukhala pamzere womwewo ndi kuchuluka kwa zigawo zogwirizana ndi mlingo wofunikira.

Nthawi imodzi, batani la mlingo limasuntha 1 unit.

Kutembenukira kulikonse kwa batani la mlingo kumadina.

Mlingo suyenera kusankhidwa powerengetsa makina, popeza mulingo wolakwika umatha kupezeka mwanjira iyi.

Mlingowo ungasinthidwe ndikutembenuzira batani la mlingo m'malo ofunikira mpaka chithunzi chofanana ndi chofunikira chikuwonekera pawindo la chizindikiritso pamzera womwewo ndi chizindikiro cha mlingo.

Ngakhale manambala amawonetsedwa pamulingo. Manambala osavomerezeka, nambala 1 itatha, akuwonetsedwa ndi mizere yolimba.

Nthawi zonse muyenera kuwunika nambala yomwe ili pawindo la chizindikiritso cha mankhwalawo kuti muwonetsetse kuti mulondola.

Ngati insulin yotsalira mu cholembera sichingafunikire, wodwala sangapereke mlingo womwe ukufunidwa ndi cholembera ichi.

Ngati mayunitsi ambiri akufunika kuposa omwe atsalira m'khola, wodwalayo angathe:

- lowetsani voliyumu yotsalira mu cholembera, kenako gwiritsani ntchito cholembera chatsopano kuti mulowetse gawo lotsala,

- tengani cholembera chatsopano ndi kulowa muyezo wathunthu.

Katswiri wochepa wa insulin amatha kukhalabe m'khola, lomwe wodwalayo sangathe kupereka.

Ndikofunikira kupanga jakisoni wa insulin mosamalitsa monga momwe adokotala adasonyezera.

Pa jakisoni aliyense, sinthani (sinthani) malo omwe jekeseni.

Osayesa kusintha mlingo pakati pa jakisoni.

Gawo 10. Sankhani malo a jakisoni - insulin imalowetsedwa mkatikati mwa khoma lamkati, matako, m'chiuno kapena mapewa. Konzani khungu monga momwe adalimbikitsira ndi dokotala.

Gawo 11. Ikani singano pansi pa khungu. Kanikizani batani la mlingo mpaka litayima. Mukugwira batani la mlingo, pang'onopang'ono kuwerengera mpaka 5, kenako chotsani ndi singano pakhungu. Osayesa kupereka insulin potembenuza batani la mlingo. Mukazungulira batani la insulin, insulin siinaperekedwe.

Gawo 12. Chotsani singano pakhungu. Ndizovomerezeka ngati dontho la insulin likatsalira kumapeto kwa singano, izi sizikhudza kulondola kwa mlingo.

Chongani nambala yomwe ili pawindo la chizindikiro:

- ngati chizindikiro chikuonetsa "0" pazenera, ndiye kuti wodwalayo walowa muyezo kwathunthu,

- ngati wodwala saona "0" pawindo la chizindikiritso cha mlingo, mankhwalawo sayenera kuchiritsidwa. Ikani singano pansi pakhungu ndipo malizitsani jakisoni,

- Ngati wodwalayo akukhulupirirabe kuti mulingo womwe sanamwe nawo, musabwereze jakisoni. Onani kuchuluka kwa shuga m'magazi ndikuchita mogwirizana ndi malangizo a dokotala,

- ngati mukuyambitsa kumwa kwathunthu ndikofunikira kupanga jakisoni awiri, musaiwale kuyambitsa jekeseni wachiwiri.

Ndi jakisoni aliyense, pisitoni imangoyenda pang'ono, ndipo wodwalayo sangathe kuwona kusintha kwake.

Ngati, mutachotsa singano pakhungu, wodwalayo awona dontho la magazi, akanikizani mosamala nsalu yoyera kapena chakumwa chaukali kumalo operekera jakisoni. Osazipukusa malowa.

Pambuyo jekeseni

Gawo 13. Valani bwino pakavalidwe kakunja ka singano.

Gawo 14 Tulutsani singano ndi chipewa ndikuitaya monga tafotokozera pansipa Kutaya zolembera ndi singano) Osasunga cholembera ndi singano yomwe idasungidwa kuti muchepetse kutulutsa kwa insulin, kutsekeka kwa singano, ndi mpweya kulowa cholembera.

Gawo 15. Ikani chipewa pa syringe cholembera, chikugwirizana ndi cholumikizira cap ndi chizindikiritso cha mlingo ndikuchikanikiza.

Kutaya zolembera ndi singano

Ikani singano zogwiritsidwa ntchito mu chidebe cha sharps kapena chidebe cholimba cha pulasitiki chokhala ndi chivindikiro cholimba. Osataya singano m'malo osankhidwa zinyalala za m'nyumba.

Chingwe chomwe chagwiritsidwa ntchito chitha kutayidwa ndi zinyalala za m'nyumba mutachotsa singano.

Lumikizanani ndi adokotala za momwe mungatayire chida chanu cha ubweya.

Malangizo ogwiritsira ntchito masingano pakufotokozerawa samachotsa malamulo, malangizo kapena mfundo zoyambitsidwa ndi bungwe lililonse.

Zilemba Zosagwiritsidwa Ntchito Sungani zolembera zosagwiritsidwa ntchito mufiriji pamtunda wa 2 mpaka 8 ° C. Musamayimitse insulin ngati yauma, musagwiritse ntchito. Ma cholembera osagwiritsidwa ntchito amatha kusungidwa mpaka tsiku lotha ntchito likawonetsedwa, ngati atasungidwa mufiriji.

Chingwe cha syringe chikugwiritsidwa ntchito. Sungani cholembera chomwe chikugwiritsidwa ntchito kutentha tsopano mpaka 30 ° C pamalo otetezedwa ndi kutentha ndi kuwala. Tsiku lotha ntchito likatulutsidwa pamapaketi, cholembera chogwiritsidwa ntchito chimayenera kutayidwa, ngakhale insulin ikadaliramo.

Zambiri pazotetezedwa ndikugwiritsa ntchito bwino cholembera

Sungani cholembera ndi singano kuchokera kwa ana.

Osagwiritsa ntchito cholembera ngati gawo lililonse lachiwoneka losweka kapena lowonongeka.

Nthawi zonse tengani cholembera chotsekereza ngati cholembera chachikulu sichitha kapena kusweka.

Zovuta

Ngati wodwalayo sangathe kuchotsa kapu ku cholembera, muzipotoza, kenako ndikukoka.

Ngati mlingo woyimba piritsi utakankhidwa mwamphamvu:

- Kanikizani batani loyimba pang'onopang'ono. Kukanikiza pang'onopang'ono batani la kuyimba pang'onopang'ono kumapangitsa kuti jakisoniyo akhale wosavuta

- singano ikhoza kukhala yotsekedwa. Ikani singano yatsopano ndikuyang'ana cholembera kuti mupeze mankhwala,

-Nkutheka kuti fumbi kapena tinthu tina talowa mu cholembera. Ponyani cholembera choterocho ndikutenga chatsopano.

Ngati wodwalayo ali ndi mafunso kapena mavuto okhudzana ndi kugwiritsa ntchito cholembera cha syringe ya QuickPen ™, lemberani ndi Eli Lilly kapena dokotala wanu.

Kutulutsa Fomu

Njira yothetsera kulowetsedwa kwamkati ndi makina, 100 IU / ml.

Makatoni 3 ml ya mankhwalawa katiriji. Makatiriji 5 pachimake. 1 bl. mu paketi okhala ndi makatoni. Kuphatikiza apo, pothira mankhwalawa ku kampani ya Russia JSC "ORTAT", chomata chimayikidwa kuti chithe kutsegulira koyamba.

QuickPen ™ Syringe Pens. 3 ml ya mankhwalawa katiriji wopangidwira cholembera QuickPen ™. 5RPPPPPRS yolembera mu cholembera. Kuphatikiza apo, pothira mankhwalawa ku kampani ya Russia JSC "ORTAT", chomata chimayikidwa kuti chithe kutsegulira koyamba.

Wopanga

Kupanga kwa fomu yomalizira ya Mlingo ndi kuyika koyambirira: Lilly France, France (cartridgeges, QuickPen ™ syringe pens). 2 Ru du Colonel Lilly, 67640 Fegersheim, France.

Katundu wachiwiri ndi kuwongolera kwapamwamba: Lilly France, France. 2 Ru du Colonel Lilly, 67640 Fegersheim, France.

Kapena Eli Lilly ndi Company, USA. Indianapolis, Indiana, 46285 (QuickPen ™ Syringe Pens).

Kapena JSC "ORTAT", Russia. 157092, dera la Kostroma, chigawo cha Susaninsky, ndi. Kumpoto, microdistrict. Kharitonovo.

Ofesi Yoyimira ku Russia / Adilesi Yakuyitanitsa: Ofesi Yoyimira ku Moscow ya Eli Lilly Vostok S.A. JSC, Switzerland. 123112, Moscow, Presnenskaya nab., 10.

Tele. ((495) 258-50-01, fakisi: (495) 258-50-05.

Lilly Pharma LLC ndiye mlendo yekha wa Humalog ® ku Russian Federation.

Pharmacokinetics

Zogulitsa ndi kugawa

Pambuyo pakuyang'anira sc, insulin Lyspro imatengedwa mwachangu ndikufika ku Cmax m'madzi a m'magazi pambuyo pa mphindi 30-70. Vd ya insulin lyspro ndi insulin wamba ya anthu ndi ofanana ndipo ali mgulu la 0.26-0.36 l / kg.

Ndi sc makonzedwe a T1 / 2 a insulin, lyspro ili pafupifupi ola 1. Odwala omwe ali ndi impso ndi hepatic insufficiency amakhala ndi kuchuluka kwa mayamwidwe a lyspro insulin poyerekeza ndi masiku onse a insulin.

Zotsatira zoyipa

Zotsatira zoyipa zomwe zimakhudzana ndi zotsatira zazikulu za mankhwalawa: hypoglycemia. Hypoglycemia yayikulu imatha kutha mphamvu ya chikumbumtima (hypoglycemic chikomokere), ndipo, mwatsatanetsatane, kufa.

Zotsatira zoyipa: zamkati zimatha kugundana - kufupika, kutupa kapena kuyunkhira pamalo a jakisoni (nthawi zambiri zimatha patadutsa masiku angapo kapena masabata), kayendedwe ka ziwonetsero zina (zimachitika kangapo, koma ndizowopsa) - kuyabwa, urticaria, angioedema, kutentha, kupuma movutikira, kutsika magazi, tachycardia, kuchuluka thukuta. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo.

Zomwe zimachitika mdera: lipodystrophy pamalo opangira jakisoni.

Mikhalidwe yapadera

Kusamutsa wodwala kupita ku mtundu wina kapena mtundu wa insulin kuyenera kuchitika moyang'aniridwa ndi achipatala. Kusintha kwa zochitika, mtundu (wopanga), mtundu (mwachitsanzo, Wokhazikika, NPH, Tepi), mitundu (nyama, anthu, ma insulin analogue) ndi / kapena njira yopanga (DNA recombinant insulin kapena insulini yachikhalidwe) ingafunike kusintha kwa mlingo.

Mikhalidwe yomwe zizindikiro zoyambirira za hypoglycemia zitha kukhala zosakhudzika komanso zochepa zomwe zimaphatikizidwa zimaphatikizapo kukhalapo kwa matenda a shuga, kulimbitsa kwambiri insulin, matenda amanjenje m'matenda a shuga, kapena mankhwala, monga beta-blockers.

Odwala omwe ali ndi vuto la hypoglycemic atasamutsidwa kuchokera ku insulin yochokera ku nyama kupita ku insulin yaumunthu, zizindikiro zoyambirira za hypoglycemia zitha kutchulidwa pang'ono kapena zosiyana ndi zomwe adakumana nazo kale ndi insulin. Hypoglycemic yosasinthika kapena ma hyperglycemic zomwe zimachitika zimatha kuyambitsa chikumbumtima, chikomokere, kapena kufa.

Mlingo wosakwanira kapena kutha kwa mankhwalawo, makamaka ndi matenda a shuga a shuga, amatha kutsegula ndi hyperglycemia ndi matenda ashuga a ketoacidosis, mikhalidwe yomwe ikhoza kukhala pangozi kwa wodwalayo.

Kufunika kwa insulini kumatha kuchepa kwa odwala omwe amalephera kupweteka kwa impso, komanso kwa odwala omwe ali ndi vuto la chiwindi chifukwa cha kuchepa kwa njira ya gluconeogeneis ndi insulin metabolism. Komabe, mwa odwala omwe ali ndi vuto losatha la chiwindi, kuchuluka kwa insulin kungayambitse kuchuluka kwa insulin.

Kufunika kwa insulin kumatha kuwonjezeka ndi matenda opatsirana, kupsinjika kwamalingaliro, ndikuwonjezereka kwa kuchuluka kwa chakudya chamagulu muzakudya.

Kusintha kwa mlingo kumafunikanso ngati wodwala akuchulukitsa kapena kusintha kwachilendo kwa zakudya. Kuchita masewera olimbitsa thupi mukangomaliza kudya kumawonjezera chiopsezo cha hypoglycemia. Zotsatira za pharmacodynamics za insulin analogi zomwe zimagwira mwachangu ndikuti ngati hypoglycemia imayamba, ndiye kuti imatha kupanga jekeseni m'mbuyomu kuposa kubayidwa insulin yamunthu.

Wodwalayo ayenera kuchenjezedwa kuti ngati dokotala atayambitsa kukonzekera kwa insulin ndi kuchuluka kwa 40 IU / ml mu vial, ndiye kuti insulini sayenera kutengedwa kuchokera ku cartridge ndi insulin ya 100 IU / ml ndi syringe ya jekeseni wa insulin wochita ndi 40 IU / ml.

Ngati pakufunika kumwa mankhwala ena nthawi imodzi ndi Humalog®, wodwalayo ayenera kufunsa dokotala.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

- shuga mellitus mwa akulu ndi ana, omwe amafunikira chithandizo cha insulin kuti akhalebe ndi shuga.

Kuyanjana kwa mankhwala osokoneza bongo

Mphamvu ya Humalog's hypoglycemic imachepetsedwa ndi kulera kwapakamwa, corticosteroids, kukonzekera kwa mahomoni a chithokomiro, danazol, beta2-adrenergic agonists (kuphatikizapo rhytodrin, salbutamol, terbutaline), tricyclic antidepressants, thiazide diuretics, chlorprotixen, diazitumum zotumphukira za phenothiazine.

Zotsatira za hypoglycemic za Humalog zimapangidwira ndi ophatikiza ndi beta, ma ethanol ndi mankhwala okhala ndi ethanol, anabolic steroids, fenfluramine, guanethidine, tetracyclines, mankhwala apakamwa a hypoglycemic, salicylates (mwachitsanzo, acetylsalicylic acid, aniloprilactyl antagonists, MAP inhibitors, angiotensin II zolandila.

Humalog® sayenera kusakanikirana ndi kukonzekera kwa insulin ya nyama.

Humalog ® ikhoza kugwiritsidwa ntchito (kuyang'aniridwa ndi achipatala) kuphatikiza ndi insulin yaumunthu yayitali kapena kuphatikiza ndi hypoglycemic agents sulfonylureas.

• Mutha kugula ma Humalog 100me / ml 3ml n5 ma cartridge agrr / mu St. Petersburg mu malo ogulitsa mankhwala omwe mungakonde nawo mukayika oda pa Apteka.RU.
• Mtengo wa Humalog 100me / ml 3ml n5 cartridgeges rr d / mu St. Petersburg - 1777.10 rubles.

Mutha kupeza malo opezako pafupi kwambiri ku St.

Mitengo ya Humalog m'mizinda inanso

Dokotala amawerengera aliyense payekha, kutengera zosowa za wodwalayo. Humalog® imatha kuperekedweratu chakudya chisanafike, ngati kuli kofunikira mukangomaliza kudya.

Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Humalog® imayendetsedwa s / c ngati jakisoni kapena ngati kulowetsedwa kwa s / c pogwiritsa ntchito pampu ya insulin. Ngati ndi kotheka (ketoacidosis, matenda owopsa, nthawi pakati pa ntchito kapena nthawi ya postoperative) Humalog® ikhoza kutumikiridwa iv.

SC iyenera kuperekedwa kwa phewa, ntchafu, matako, kapena pamimba. Masamba a jakisoni ayenera kusinthidwa kuti malo omwewo asagwiritsidwerenso nthawi 1 pamwezi. Mukamayambitsa mankhwala a Humalog®, mankhwalawa ayenera kuthandizidwa kuti mankhwalawo asatenge magazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Wodwala ayenera kuphunzitsidwa njira yolondola ya jakisoni.

Bongo

Zizindikiro: hypoglycemia, limodzi ndi zizindikiro zotsatirazi: ulesi, kuchuluka thukuta, tachycardia, kupweteka mutu, kusanza, chisokonezo.

Chithandizo: Matenda ofooketsa a hypoglycemia nthawi zambiri amayimitsidwa ndikuwonjezera shuga kapena shuga wina, kapena zinthu zokhala ndi shuga.