Insulin Humulin NPH: malangizo, analogues, ndemanga

Kuyimitsidwa kwa jakisoni 100 IU / ml

Mlingo umodzi wa kuyimitsidwa uli ndi

ntchito yogwira - insulin ya anthu (DNA recombinant) 100 IU,

obwera : metasedresol ya distilled, glycerin, phenol, protamine sulfate, sodium hydrogen phosphate heptahydrate, zinc oxide (malinga ndi zinc Zn ++), hydrochloric acid 10% kusintha pH, sodium hydroxide 10% yothetsera kusintha pH, madzi a jakisoni.

Kuyimitsidwa koyera, komwe, kuyimilira, kumakhala exxpatant yowoneka bwino, yopanda utoto kapena mawonekedwe oyera. Mtengo umasinthidwa mosavuta ndikugwedezeka modekha.

Mankhwala

Humulin® NPH ndiakonzekereratu.

Kukhazikika kwa mankhwalawa ndi 1 mpaka 2 mawola atatha kugwira ntchito, mphamvu yayitali imakhala pakati pa maola 4 ndi 10, kutalika kwa nthawi ndi maola 18 mpaka 24. Chithunzi chojambulidwa (glucose uptake curve) pambuyo pa kayendetsedwe ka subcutaneous chikuwonetsedwa ngati mzere wolimba mtima pach chithunzi chomwe chili pansipa. Kusiyana kwamwini pantchito ya insulin kumadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi, ndi zina zambiri.

Humulin N NPH ndi insulin yomwe imadziwikiranso.

Chochita chachikulu cha insulin ndi kuphatikiza shuga kagayidwe. Kuphatikiza apo, ili ndi anabolic komanso anti-catabolic zotsatira. Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zosiyanasiyana zamthupi. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogeneis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.

Mlingo ndi makonzedwe

Mlingo wa Humulin® NPH amatsimikiza ndi dokotala payekha kutengera mlingo wa glycemia. Mankhwalawa amayenera kuperekedwa mosavuta. Intramuscular management ndiyotheka, koma osavomerezeka.

Jakisoni wotsekemera amayenera kuperekedwa kwa mapewa, m'chiuno, matako kapena pamimba. Malo omwe ali ndi jakisoni ayenera kusinthidwa kuti malo omwewo sawagwiritsanso ntchito mwina kamodzi pamwezi. Ndi subulinaneous ya insulin, chisamaliro chimayenera kumwedwa kuti musalowe m'mitsempha yamagazi pakubaya. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Odwala ayenera kuphunzitsidwa bwino kugwiritsa ntchito zida za insulin.

Humulin® NPH imatha kuperekedwa limodzi ndi Humulin® Regular (onani malangizo osakanikirana ndi insulin).

Ndondomeko ya insulin makonzedwe ndi munthu!

Malangizo ogwiritsira ntchito

Makatoni amtundu wa Humulin® NPH amafunika kuti azikulungika pakati pa kanjedza kangapo mpaka insulini itayambanso kupangika. Musanagwiritse ntchito, makatiriji a Humulin® NPH ayenera kugulitsidwa pakati pa manja khumi ndikugwedezeka, kutembenukira 180 komanso maulendo khumi, mpaka insulini ikhale yunifolomu ya turbid yamadzi kapena milky yoyera. Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera.

Makatoni amayenera kufufuzidwa mosamala. Musamagwiritse ntchito insulin ngati ili ndi ziphuphu mutasakaniza kapena ngati chinthu choyera chikatsalira pansi pa botolo. Osagwiritsa ntchito insulin ngati tinthu tating'ono tomwe timamatira pansi kapena makoma a vial, ndikupanga mawonekedwe a frosty.

Chipangizo cha ma cartridge sichimalola kusakanikirana ndi zomwe zili ndi insulini zina mwachindunji mu cartridge lokha. Makatoniwo sanapangidwe kuti adzazitsidwe.

Insulin yongokhala mwachidule iyenera kukokedwa mu syringe yoyamba kuti tipewe zinthu zazitali za insulini kuti zisadetse zomwe zili m'mbale. Ndikofunika kukhazikitsa osakaniza okonzeka mukangosakaniza. Kuti muwongolere kuchuluka kwa mtundu uliwonse wa insulin, mutha kugwiritsa ntchito syringe yapadera ya Humulin® Regular ndi Humulin® NPH.

Nthawi zonse gwiritsani ntchito syringe ya insulini yomwe imagwirizana ndi kuchuluka kwa insulin yomwe mukubayira.

Tsatirani malangizo a wopanga kuti muthetsanso katoni ndikuyika singano.

Sambani manja. Kuthira mafuta oyimitsira katiriji m'malo olumikizana ndi singano.

Konzani cholembera, kutsatira malangizo ogwiritsa ntchito. Ikani cartridge mu syringe cholembera.

Phatikizani singano mutachotsa filimu yoteteza.

Chotsani kapu yakunja kuchokera singano.

Chotsani mpweya kuchokera ku insulin cartridge. Muyenera kuyesa magawo 1-2 a muyezo. Tengani cholembera ndi singano ndikulowetsa nsonga ya cholembera pang'ono kuti mabulamu omwe ali mkatimo abwere pamwamba. Mukugwira cholembera ndi singano kumtunda, kanikizani jakisoni. Pitilizani mpaka dontho la Humulin® NPH lithe kumapeto kwa singano. Mafuta angapo amatha kukhalabe mu cholembera, alibe vuto. Komabe, ngati kukula kwa mabulusi ndikokwanira kwambiri, mulingo wa jakisoni wanu sudzakhala wolondola. Chongani chikuyenera kuchitika musanabaye jekeseni aliyense.

Sankhani malo pobayira.

Pukutani khungu ndi thonje la thonje lomwe litamizidwa mu mowa. Yembekezerani kuti khungu liume.

Sinthani khungu ndikupanga khola. Onetsetsani kuti malo omwe jakisoni ili pafupi 1 cm kuchokera pamalo omwe jekeseni wam'mbuyomu, ndikuwonetsetsa kuti malo osakanikirana ndi omwe analimbikitsidwa.

Fotokozerani kuchuluka kwa mankhwala a insulini mosiyanasiyana malinga ndi malangizo a dokotala komanso mogwirizana ndi malangizo a wopanga cholembera. Gwirani singano pansi pa khungu kwa masekondi 5 kuti muwonetsetse kuti mwalowa muyezo wathunthu.

Chotsani singano pakhungu mwachindunji ndikulimbikira pang'ono pa tsamba la jakisoni kwa masekondi angapo. Osatupa malo a jakisoni.

Pogwiritsa ntchito kapu yakunja ya singano, mutangoyikapo, tengani singano ndikuwononga bwinobwino. Kuchotsa singano yomweyo jakisoni itaonetsetsa kuti sisitere, imalepheretsa kutulutsa insulin ndi mpweya, komanso kutheka kwa singano.

Ikani chipewa pa cholembera.

Kuwonongeka kwa ma cartridge ndi singano.

Osamagwiritsanso ntchito singano. Chotsani masingano ogwiritsa ntchito moyenera. Osagawana cartridge yanu kapena singano ndi anthu ena. Chifukwa chake mumakhala pachiwopsezo chotenga kachiromboka kapena kutenga matenda oopsa kwa iwo. Masingano ndi zolembera ndizongogwiritsa ntchito nokha. Gwiritsani ntchito makatoni mpaka atakhala opanda kanthu, pambuyo pake azitha kuwataya moyenerera. Katundu wosagwiritsidwa ntchito kapena zogulitsa ziyenera kutayidwa malinga ndi malamulo apafupi.

Zotsatira zoyipa

Zotsatira zoyipa zomwe zimakhudzana ndi vutoli:

hypoglycemia ndizotsatira zoyipa zomwe zimachitika ndi makonzedwe a insulin, kuphatikiza Humulin® NPH.

Zizindikiro wofatsa kwa zolimbitsa hypoglycemia : kufooka, malaise, palpitations, kumva kugunda kwa manjenje m'manja, miyendo, milomo kapena lilime, kunjenjemera, kupweteka kwa mutu, thukuta lakuzizira, chizungulire, kusokonezeka kwa tulo, kugona, kugona tulo, nkhawa, kusakhazikika, kusawona bwino, kuyankhula mosavomerezeka, kusokonezeka maganizo, kusakhazikika, kulephera kukhazikika, zochitika zam'machitidwe, kusintha kwa umunthu, mayendedwe osagwedezeka, njala.

Zizindikiro kwambiri hypoglycemia: kukhumudwa, kusazindikira, kukhudzika. Mwapadera, hypoglycemia ikhoza kufa.

thupi lawo siligwirizana (pafupipafupi kuyambira pa 1/100 mpaka 1/10) ngati redness, kutupa, kapena kuyabwa pamalo opangira jakisoni nthawi zambiri amasiya pakadutsa masiku angapo mpaka milungu ingapo. Nthawi zina, izi zimachitika chifukwa cha zifukwa zosakhudzana ndi insulin, mwachitsanzo, mkwiyo pakhungu ndi wothandizira kuyeretsa kapena jakisoni wosayenera.

zokhudza zonse thupi lawo siligwirizana (pafupipafupi mankhwala

Achire zotsatira akuyamba ola limodzi jekeseni.
Kutsitsa kwa shuga kumatenga pafupifupi maola 18.
Zotsatira zazikulu zimakhala pambuyo pa maola awiri mpaka maola 8 kuchokera pakukonzekera.

Kusintha kwakanthawi kwamankhwala kumadalira malo omwe amayimitsidwa ndi kuyendetsa galimoto kwa wodwalayo. Izi zimayenera kuganiziridwanso popereka dongosolo komanso kuchuluka kwa makonzedwe. Popeza nthawi yayitali zotsatira zake, Humulin NPH imayikidwa pamodzi ndi insulin yochepa komanso ya ultrashort.

Kugawa ndi kutulutsa thupi:

Insulin Humulin NPH simalowa mu chotchinga cha hematoplacental ndipo samatuluka m'matumbo a mkaka ndi mkaka.
Inactivine mu chiwindi ndi impso kudzera enzyme insulinase.
Kuthetsa mankhwalawa makamaka kudzera impso.

Kufotokozera za mtundu wa kipimo

Kuyimitsidwa kwa ma s / c kukongoletsa kwamtundu woyera, womwe umatuluka, ndikupanga zoyera komanso zowoneka bwino, zopanda utoto kapena zowoneka bwino kwambiri, mpweya woterewu umatha kusunthika modekha. Kuyimitsidwa kwa ma s / c kukongoletsa kwamtundu woyera, womwe umatuluka, ndikupanga zoyera komanso zowoneka bwino, zopanda utoto kapena zowoneka bwino kwambiri, mpweya woterewu umatha kusunthika modekha. Kuyimitsidwa kwa ma s / c kukongoletsa kwamtundu woyera, womwe umatuluka, ndikupanga zoyera komanso zowoneka bwino, zopanda utoto kapena zowoneka bwino kwambiri, mpweya woterewu umatha kusunthika modekha.

Zosafunikira zoyipa zimaphatikizapo:

hypoglycemia ndimavuto owopsa komanso osakwanira kupanga. Kuwonetsedwa ndi kusazindikira, komwe kumatha kusokonezedwa ndi chikomokere cha hyperglycemic,
mawonetseredwe amatsitsi omwe amapezeka pamalo a jakisoni (redness, kuyabwa, kutupa),
kutsutsika
kupuma movutikira
hypotension
urticaria
tachycardia
lipodystrophy - mankhwala a kwawo a subcutaneous mafuta.

Zotsatira za pharmacological

1 ml ya insulin ya anthu 100 IU ndi kuyimitsidwa kwamitundu iwiri kapena kusakaniza: sungunuka wa insulin ya anthu 30% kuyimitsidwa kwa isophan insulin 70% Othandizira: distill m-cresol (1.6 mg / ml), glycerol, phenol (0.65 mg / ml), protamine sulfate , sodium phosphate dibasic, zinc oxide, madzi d / ndi, hydrochloric acid, sodium hydroxide. 1 ml ya insulin ya anthu 100 IU ndi kuyimitsidwa kwamitundu iwiri kapena kusakaniza kwa: soluble human insulin solution 30% isofanimitsa kuyimitsidwa kwa insulini 70% Excipients: metacresol, glycerol (glycerin), phenol, protamine sulfate, sodium hydrogen phosphate, zinc oxide, madzi d / ndi. , hydrochloric acid (10% yankho) ndi / kapena sodium hydroxide (10% yankho) kuti apange gawo lofunikira la pH. insulin ya anthu 100 IU ndi kuyimitsidwa kwamitundu iwiri kapena kusakaniza kwa: madzi osungunuka aanthu 30% kuyimitsidwa kwa isophane insulin 70% Othandizira: distill m-cresol (1.6 mg / ml), glycerol, phenol (0.65 mg / ml), protamine sulfate, sodium dibasic phosphate, zinc oxide, madzi d / ndi, hydrochloric acid, sodium hydroxide.

Malamulo ogwiritsira ntchito

Mankhwalawa amayenera kuperekedwa pansi pa khungu la mapewa, m'chiuno, matako kapena khoma lamkati, ndipo nthawi zina jakisoni wamkati imatheka.
Pambuyo pa jekeseni, simuyenera kukanikiza mwamphamvu ndikulimbira malo omwe akhudzidwa nawo.
Ndi zoletsedwa kugwiritsa ntchito mankhwalawa.
Mlingo umasankhidwa payekha ndi endocrinologist ndipo umatengera zotsatira za kuyezetsa magazi kwa shuga.

Algorithm yokhudza makulidwe a insulin Humulin NPH

Humulin mumbale mu mbale musanagwiritse ntchito uyenera kusakanizidwa ndikulowetsa vial pakati pa kanjedza mpaka khungu la mkaka litawonekera. Osagwedezeka, thovu, kapena kugwiritsa ntchito insulin yotsalira pamakoma a vial.
Humulin NPH m'matakatoni osangosuntha pakati pa manja, kubwereza kayendedwe ka 10, komanso kusakaniza, modekha ndikusintha cartridge. Onetsetsani kuti insulin ndi yoyenera kuyendetsedwa poyang'anira kusasinthasintha ndi mtundu. Payenera kukhala zofanana pamtundu wa mkaka. Komanso musagwedeze kapena kufumba mankhwala. Osagwiritsa ntchito yankho ndi phala kapena phala. Ma insulin ena sangayikiridwe katiriji ndipo sangathe kudzazidwanso.
Cholembera cha syringe chili ndi 3 ml ya insulin-isophan pa mlingo wa 100 IU / ml. Pa jakisoni 1, lowetsani osaposa 60 IU. Chipangizocho chimalola dosing ndi kulondola kwa 1 IU. Onetsetsani kuti singano ndiyomatirira pachidacho.

Sambani manja pogwiritsa ntchito sopo ndikuwachiza ndi antiseptic.

Sankhani malo a jakisoni ndikuchiza khungu ndi yankho la antiseptic.

Masamba obayira enanso kuti malo omwewo sawagwiritsanso ntchito kamodzi pamwezi.

Zomwe zimagwiritsidwa ntchito pa cholembera cha syringe

Chotsani kapu poikoka m'malo mozunguliza.
Onani insulin, moyo wa alumali, kapangidwe kake ndi mtundu wake.
Konzani singano ya syringe monga tafotokozera pamwambapa.
Pukuta singano mpaka itakhala yolimba.
Chotsani zisoti ziwiri ku singano. Kunja - osataya.
Onani kuchuluka kwa insulin.
Pindani khungu ndikubaya singano pansi pakhungu pakona kwama degree 45.
Yambitsani insulini pogwira batani ndi chala chanu mpaka chitayima, kuwerengetsa pang'onopang'ono m'maganizo mpaka 5.
Mukachotsa singano, ikani nyemba za mowa pamalo a jekeseni osapaka kapena kupwanya khungu. Nthawi zambiri, dontho la insulin limatha kukhalabe kumapeto kwa singano, koma osatayikira, zomwe zikutanthauza kuti mlingo wosakwanira.
Tsekani singano ndi kapu yakunja ndikuitaya.

Kuyanjana kwina ndi mankhwala ena

Mankhwala omwe amalimbikitsa Humulin:

mapiritsi ochepetsa shuga,
antidepressants - monoamine oxidase inhibitors,
Hypotonic mankhwala ochokera pagulu la ACE zoletsa ndi beta blockers,
kaboni anhydrase zoletsa,
imidazoles
tetracycline mankhwala opha tizilombo,
Kukonzekera kwa lifiyamu
Mavitamini B,
theofylline
mankhwala okhala ndi zakumwa zoledzeretsa.

Mankhwala osokoneza bongo omwe amalepheretsa insulin Humulin NPH:

mapiritsi olembera
glucocorticosteroids,
mahomoni a chithokomiro,
okodzetsa
mankhwala antidepressants,
othandizira omwe amachititsa kuti mitsempha ichite chisoni,
calcium blockers,
narcotic analgesics.

Malangizo apadera ogwiritsa ntchito

Mankhwala ayenera kuperekedwa ndi dokotala. Chokani ku pharmacies ndi mankhwala. Pochita mankhwala ndi Humulin NPH, kuwunika pafupipafupi kuchuluka kwa shuga kumafunika. Pamaso pa matenda ophatikizika - funsani dokotala kuti musinthe mlingo.

Dzina la malonda akukonzekera:
HUMULIN ® NPH

Dzinalo Losagwirizana Ndi Mayiko Onse (INN):
Isulin Insulin (Umisiri wa Majini a Anthu)

Mlingo
Kuyimitsidwa kwa makina oyang'anira

Kufotokozera:
Kuyimitsidwa koyera komwe kumachoka, ndikupanga koyera koyera komanso kowoneka bwino, kopanda mtundu kapena pafupifupi wopepuka. Mtengo umasinthidwa mosavuta ndikugwedezeka modekha.

Gulu la Pharmacotherapeutic
Hypoglycemic wothandizila - sing'anga-insulin.

Nambala ya ATX A10AC01.

Mankhwala
Mankhwala
Humulin ® NPH ndi insulin yothandizanso anthu. Chochita chachikulu cha insulin ndi kuphatikiza shuga kagayidwe. Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zake zosiyanasiyana zamthupi.Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogeneis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.
Humulin NPH ndi insulin yomwe ikukonzekera. Kukhazikika kwa mankhwala ndi ola limodzi pambuyo pa kukonzekera, mphamvu yayikulu imakhala pakati pa maola awiri ndi asanu ndi atatu, kutalika kwa nthawi ndi maola 18-20. Kusiyana kwamwini pantchito ya insulin kumadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi, ndi zina zambiri.

Pharmacokinetics
Kukwanira kwathunthu ndi kuyambika kwa mphamvu ya insulin kumadalira malo a jakisoni (m'mimba, ntchafu, matako), mlingo (kuchuluka kwa insulin), kuchuluka kwa insulini mu mankhwalawa, ndi zina. Amawonongedwa ndi insulinase makamaka m'chiwindi ndi impso. Amachotsa impso (30-80%).

Zosiyanitsa

Zowoneka mosiyanasiyana zamitundu mitundu:

Humulin NPH . Ili m'gulu laopanga insulini zapakatikati. Mwa mankhwala omwe amapezeka nthawi yayitali monga othandizira odwala matenda a pancreatic hormone, mankhwalawa amaperekedwa kwa anthu odwala matenda ashuga. Monga lamulo, zochita zake zimayamba mphindi 60 pambuyo pa kutsata mwachindunji. Ndipo kuchuluka kwake kwakukulu kumawonedwa pambuyo pafupifupi maola 6. Kuphatikiza apo, zimatha pafupifupi maola 20 motsatana. Nthawi zambiri, odwala amagwiritsa ntchito jakisoni zingapo nthawi imodzi chifukwa chachedwa chifukwa cha mankhwala.
Humulin M3 . Ndiwosakanikirana kwapadera ndi ma insulin osakhalitsa. Ndalama zotere zimakhala ndi kuchuluka kwa NPH-insulin yayitali komanso pancreatic timadzi ta ultrashort komanso zochitika zazifupi,
Humulin Wokhazikika . Amagwiritsidwa ntchito poyambira kudziwa matenda. Monga mukudziwa, ikhoza kugwiritsidwa ntchito ndi azimayi oyembekezera. Mankhwalawa ndi m'gulu la mahomoni a ultrashort. Ndi gululi lomwe limatulutsa mwachangu kwambiri komanso nthawi yomweyo limachepetsa shuga la magazi. Gwiritsani ntchito mankhwala musanadye. Izi zimachitika kuti njira yogaya mafuta imathandizira kufulumiza kuyamwa kwa mankhwalawa munthawi yochepa kwambiri. Mahomoni ofulumira kuchitapo kanthu amatengedwa pakamwa. Zachidziwikire, ayenera kubweretsedwa kumalo amadzimadzi.

Ndikofunika kudziwa kuti insulini yokhala ndi nthawi yochepa ili ndi zotsatirazi:

ayenera kumwedwa pafupifupi mphindi 35 asanadye,
kuti musanayambike, muyenera kulowa ndi jakisoni,
Nthawi zambiri imayendetsedwa m'mimba m'mimba,
jakisoni wa mankhwala akuyenera kutsatiridwa ndi chakudya chotsatira kuti athetse zonse zomwe zingachitike.

Kodi pali kusiyana kotani pakati pa Humulin NPH insulin ndi Rinsulin NPH?

Humulin NPH ndi chithunzi cha insulin ya anthu. Rinsulin NPH imafanananso ndi mahomoni a pancreatic a anthu. Ndiye pali kusiyana kotani pakati pa awiriwa?

Ndikofunika kudziwa kuti onsewa ali m'gulu la mankhwala omwe amakhala ali nthawi yayitali kuchitidwe. Kusiyana kokhako pakati pa mankhwalawa ndikuti Humulin NPH ndi mankhwala achilendo, ndipo Rinsulin NPH amapangidwa ku Russia, motero mtengo wake umakhala wotsika kwambiri.

Wopanga

Humulin NPH imapangidwa ku Czech Republic, France, ndi UK. Humulin Wokhazikika wopangidwa ku USA. Humulin M3 amapangidwa ku France.

Monga tanena kale, Humulin NPH amatanthauza mankhwala omwe amakhala ali pakatikati pa zochita. Humulin Nthawi zonse amadziwika kuti ndi wowerengeka mwachidule. Koma Humulin M3 amadziwika kuti ndi insulin yokhala ndi yochepa.

Kuti musankhe ma analogue ofunikira a mahomoni a pancreatic ayenera kungokhala akatswiri a endocrinologist. Osadzisilira.

Humulin M3 mavuto

Zotsatira zoyipa zomwe zimakhudzana ndi zotsatira zazikulu za mankhwalawa: hypoglycemia. Hypoglycemia yamphamvu imatha kubweretsa kusokonezeka kwa chikumbumtima ndipo (makamaka zikachitika) kufa. Thupi lawo siligwirizana: zimachitika matupi awo sagwirizana - hyperemia, kutupa kapena kuyunkhira pamalo a jekeseni (nthawi zambiri amayima patadutsa masiku angapo mpaka masabata angapo), zotsatira zoyipa zamkati (zimachitika kangapo, koma zimakhala zowopsa) - kuyamwa pang'ono, kufupika, kupuma pang'ono , kuchepa kwa magazi, kuchuluka kwa mtima, kuchuluka thukuta. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo. Zina: mwayi wokhala ndi lipodystrophy ndizochepa.

Malo osungira

Sungani kuzizira (t 2 - 5)
osayandikira ana
sungani pamalo amdima

Zambiri zoperekedwa ndi State Register of Medicines.

Berlinsulin N, Insuman Comb, Humalog Mix, Humulin M1, Humulin M2.

Kufotokozera
Makhalidwe
Malangizo ogwiritsira ntchito
Zikalata
Funsani funso
Ndemanga
Kupereka
Za ife
Ma Analogi pazogwira ntchito

Contraindication

Hypersensitivity kupita ku insulin kapena chimodzi mwazinthu za mankhwala.

Momwe mungadziwire kuperewera kwa glucose komanso kupereka thandizo kwa omwe akukhudzidwayo

Anapulumutsa anthu masauzande ambiri ndipo anasintha mbiri

Mutha kufunsa funso lililonse lomwe muli nalo pazogulitsa kapena sitolo.

Akatswiri athu oyenerera angakuthandizeni.

Kutumiza kovomerezeka

Imachitika mkati mwa maola atatu kuyambira nthawi yoyitanitsa ndipo imawononga ma ruble 300.

Mutha kunyamula nokha oda yanu komanso kwaulere, mu pharmacy ku adilesi: 41 Mitinskaya Street, Moscow.

Malo osankha amakhala otseguka tsiku lililonse kuyambira 10:00 mpaka 21:00. Onetsetsani kuti mukugwirizana nthawi yanu yakubwera ndi wothandizira!

Ma oda omwe adalandilidwa pambuyo pa 20:00 amaperekedwa tsiku lotsatira,
Tikuyang'ana kuti ngati oda yanu idalandilidwa kuyambira 21:00 mpaka 9:00, imakonzedwa ndi ogwiritsa ntchito athu pokhapokha 9:00,
"Kutumiza" - sizitanthauza ntchito yoyendetsedwa ndi lamulo. Zogulitsa sizibweretsedwa ndi ogwira ntchito ku pharmacy. Malo ogulitsira ali pa intaneti sindiye omwe amachititsa. Ndalama yobweretsera si ndalama zolipirira, koma mawonekedwe othokoza kwa wothandizira amene wabweretsa kugula,
Pakuvomereza kuti kuperekedwa ndikololedwa kwa inu ndi lamulo la Russian Federation, mukutsimikizira kuti mwazolowera zomwe zalembedwa pagawo lokondera ndikukhala ndi chitsimikizo kuti mbiri yanu ikugwirizana ndi zomwe zafotokozedwa mu Article 2 ya Federal Law of Russian Federation ya 09.01.1997 No. 5-FZ ndi kwa onse oyenda pa Order of Labor Glory ”(monga momwe zidasinthidwira pa Julayi 2, 2013) ndi Article 1.1 ya Law of the Russian Federation yomwe idalembedwa pa 01.15.1993 No.

Takhazikitsa BoxkaRu kuti ikhale yabwino.

Kusankha ndi kugula mankhwala oyenera tsopano ndikosavuta. Lamula mankhwalawa ndipo tidzakupereka. Tili ndi gawo lalikulu komanso ntchito yabwino, yomwe sitikukayikira kuti mungayamikire. Tikutsimikizira zabwino zokhazokha kuchokera kwa ogulitsa wamkulu azamankhwala pamitengo yotsika kwambiri.

Zikomo chifukwa chokhala nafe!

Zambiri, TabletRu

1 ml ya kuyimitsidwa kuli ndi insulin biphasic genetic engineering 100 IU.

Malangizo apadera:

Kusamutsa wodwala kupita ku mtundu wina wa insulin kapena kukonzekera kwa insulini ndi dzina lina lamalonda kuyenera kuchitika moyang'aniridwa ndi achipatala. Zosintha mu zochitika za insulin, mtundu wake (mwachizolowezi, NPH), mitundu (porcine, insulin yaumunthu, analogue ya insulin) kapena njira yopangira (DNA recombinant insulin kapena insulini yachikhalidwe) ingafune kusintha kwa mlingo.

Kufunika kwa kusintha kwa mankhwalawa kungafunike kale pokhazikitsidwa ndi insulin yokonzekera pambuyo pokonzekera insulin ya nyama kapena pang'onopang'ono patadutsa milungu ingapo kapena miyezi ingapo mutasamutsidwa.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe ka kayendedwe: panthawi ya hypoglycemia, wodwala amatha kufooketsa chidwi cha chidwi ndikuchepetsa kuthamanga kwa zochitika zama psychomotor. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa ndi ofunika kwambiri.

Odwala ayenera kulangizidwa kuti azisamala kuti asamayendetse hypoglycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofatsa kapena zosapezekapo zizindikiro za hypoglycemia kapena kukula pafupipafupi kwa hypoglycemia. Zikatero, adotolo amayenera kuwunika momwe wodwala angayendetsere galimoto.

Mitundu ndi mitundu yotulutsidwa kwa Humulin

Insulin Humulin ndi mahomoni omwe amabwerezeranso insulin yopanga thupi la munthu, kapangidwe ka amino acid ndi kulemera kwa maselo. Ndizobwerezanso, kutanthauza kuti, zimapangidwa molingana ndi njira zopangira ma genetic. Mlingo wowerengeka wa mankhwalawa ukhoza kubwezeretsa kagayidwe kazakudya mwa anthu omwe ali ndi matenda ashuga komanso kupewa mavuto.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

Matenda a shuga ndi omwe amayambitsa pafupifupi 80% yonse yamikwingwirima ndi kuduladula. Anthu 7 mwa anthu 10 amafa chifukwa cha mitsempha ya mtima kapena ubongo. Pafupifupi nthawi zonse, chifukwa chomaliza chomaliza ndi chimodzimodzi - shuga wamwazi.

Shuga akhoza ndipo ayenera kugwetsedwa; Koma izi sizichiritsa matendawa, koma zimangothandiza kulimbana ndi kufufuza, osati zomwe zimayambitsa matendawa.

Mankhwala okhawo omwe amalimbikitsidwa mwalamulo kwa odwala matenda ashuga komanso ogwiritsidwa ntchito ndi endocrinologists pantchito yawo ndi Ji Dao shuga patch.

Kugwiritsa ntchito bwino kwa mankhwalawa, kuwerengera malinga ndi njira yokhazikika (kuchuluka kwa odwala omwe achiwonjezere kuchuluka kwa odwala omwe ali mgulu la anthu 100 omwe adachitiridwa chithandizo):

Matenda a shuga - 95%
Kuthetsa kwa mitsempha thrombosis - 70%
Kuthetsa kwa kugunda kwamtima kwamphamvu - 90%
Kuthana ndi kuthamanga kwa magazi - 92%
Kulimbitsa tsiku, kukonza kugona usiku - 97%

Opanga Ji Dao si bungwe lazamalonda ndipo amalipiridwa ndi boma. Chifukwa chake, tsopano wokhala aliyense ali ndi mwayi wopeza mankhwalawo kuchotsera 50%.

Humulin Wokhazikika - Ili ndi yankho la insulin yoyera, amatanthauza mankhwala osakhalitsa. Cholinga chake ndikuthandizira shuga kuchokera m'magazi kuti alowe m'maselo, pomwe amagwiritsidwa ntchito ndi thupi mphamvu. Nthawi zambiri imagwiritsidwa ntchito molumikizana ndi insulin yapakatikati kapena yayitali. Zokha zimatha kuperekedwa ngati wodwala ali ndi matenda ashuga.
Humulin NPH - kuyimitsidwa komwe kumapangidwa kuchokera ku insulin yaumunthu ndi protamine sulfate. Chifukwa cha izi, mphamvu yotsitsa shuga imayamba pang'onopang'ono kuposa ya insulin yayifupi, ndipo imatenga nthawi yayitali. Makina awiri patsiku ndi okwanira kusintha glycemia pakati pa chakudya. Nthawi zambiri, Humulin NPH imayikidwa limodzi ndi insulin yocheperako, koma ndi mtundu wa 2 wodwala umatha kugwiritsidwa ntchito pawokha.
Kodi kukonzekera kw magawo awiri okhala ndi 30% insulin Nthawi zonse ndi 70% - NPH. Zochepa zomwe zimapezeka pamtundu wa Humulin M2, zimakhala ndi 20:80. Chifukwa chakuti gawo la mahomoni limayikidwa ndi wopanga ndipo siliganizira zofuna za wodwalayo, shuga yamagazi ndi chithandizo chake silingathe kuyendetsedwa bwino ngati mukugwiritsa ntchito insulin yayifupi komanso yapakati. Humulin M3 angagwiritsidwe ntchito ndi odwala matenda ashuga, omwe chikhalidwe chimalimbikitsidwa.

Kutalika kwa malangizo:

Ma humulin onse omwe amapangidwa ndi Humulin pano ali ndi U100, chifukwa chake ndioyenera kukhala masiku ano a insulin komanso ma syringe.

10 ml magalasi Mbale
makatoni azitsulo, okhala ndi 3 ml, phukusi la zidutswa 5.

Humulin insulin imayang'aniridwa pang'onopang'ono, mozama - intramuscularly. Kuwongolera kwa intravenous kumaloledwa kokha kwa Humulin Regular, imagwiritsidwa ntchito pochotsa ndipo iyenera kuchitidwa kokha moyang'aniridwa ndi achipatala .

Zizindikiro ndi contraindication

Malinga ndi malangizo, Humulin ikhoza kuperekedwa kwa odwala onse omwe ali ndi vuto lalikulu la insulin. Nthawi zambiri zimawonedwa mwa anthu omwe ali ndi matenda amtundu wa 1 kapena wopitilira 2 years. Kuchiza kwa insulin kwakanthawi kumakhala kotheka ngati muli ndi mwana, chifukwa mankhwala ochepetsa shuga amaletsedwa panthawiyi.

Humulin M3 amangolembera okhawo odwala achikulire, omwe kugwiritsa ntchito njira yolimbikitsira insulin kumakhala kovuta. Chifukwa cha chiwopsezo chowonjezeka cha zovuta za matenda osokoneza bongo mpaka azaka 18, Humulin M3 ali osavomerezeka.

Zotsatira zoyipa:

chifukwa cha mankhwala osokoneza bongo ambiri a insulin, osawerengeka zolimbitsa thupi, kusowa kwa chakudya mu chakudya.
Zizindikiro za chifuwa, monga zotupa, kutupa, kuyabwa, komanso redness kuzungulira malo a jekeseni. Amatha kuchitika chifukwa cha insulin yonse ya anthu komanso mankhwala othandizira a mankhwalawo. Ngati ziwengo zikupitilira mkati mwa sabata limodzi, Humulin adzasinthidwa ndi insulini ina.
Kupweteka kwapakhosi kapena kupsinjika, kuwonjezeka kwa mtima kumatha kuchitika pomwe wodwalayo akusowa kwambiri potaziyamu. Zizindikiro zimatha atachotsa kuchepa kwa macronutrient iyi.
Sinthani makulidwe amkhungu ndi minofu yolowera m'malo opaka jekeseni pafupipafupi.

Kuyimitsa kuphatikiza kwa insulini kumakhala koopsa, chifukwa chake, ngakhale pakachitika zosagwirizana, chithandizo cha insulini chikuyenera kupitilizidwa mpaka mukakumana ndi dokotala.

Odwala ambiri omwe amadziwika ndi Humulin samakumana ndi zovuta zina zina kupatula hypoglycemia.

Humulin - malangizo ogwiritsira ntchito

Kuwerengera Mlingo, kukonzekera jakisoni ndi makonzedwe a Humulin ndi ofanana ndi insulin ina yokonzekera nthawi yofanana. Kusiyanitsa kokha ndi nthawi musanadye . Mu Humulin pafupipafupi ndi mphindi 30. Ndikofunika kukonzekera kudziwongolera koyamba kwa mahomoni isanakwane, mutawerenga mosamala malangizo ogwiritsa ntchito.

Kukonzekera

Insulin iyenera kuchotsedwa mufiriji pasadakhale kuti kutentha kwa yankho atapeza chipinda . Makatoni kapena botolo la osakanikirana la mahomoni okhala ndi protamine (Humulin NPH, Humulin M3 ndi M2) amayenera kukukhidwira pakati pama manja kangapo ndikuwatembenukira mmwamba kuti kuyimitsidwa kumatha kusungunuka kwathunthu ndipo kuyimitsidwa kumapeza yunifolomu ya milky popanda kulowa. Gwedezani mwamphamvu kuti mupewe kuchuluka kwakanthawi koyimitsidwa ndi mpweya. Humulin Yokhazikika sikufuna kukonzekera kotere, imakhala yowonekera nthawi zonse.

Kutalika kwa singano kumasankhidwa mwanjira yoti muwonetsetse jakisoni wambiri komanso osalowetsa minofu. Mapensulo a syringe oyenera kukhala ndi insulin Humulin - Humapen, BD-pen ndi fanizo lawo.

Insulin imalowetsedwa m'malo omwe amapanga mafuta minofu: m'mimba, ntchafu, matako ndi mikono yakumtunda. Kulowetsedwa mwachangu komanso kwamayendedwe m'magazi kumayang'aniridwa ndi jakisoni m'mimba, kotero Humulin Regular imayalidwa pamenepo. Kuti machitidwe a mankhwalawa atsatire malangizo, ndizosatheka kuwonjezera magazi mwanjira ya jakisoni: kupukuta, kupukusa, ndikuviika m'madzi otentha.

Mukamayambitsa Humulin, ndikofunikira kuti musathamangire: sonkhanitsani pang'onopang'ono khungu popanda kumata minofu, pang'onopang'ono jekeseni mankhwalawo, kenako ndikuyika singano pakhungu kwa masekondi angapo kuti yankho lisayambike kutayikira. Kuti muchepetse chiopsezo cha lipodystrophy ndi kutupa, singano zimasinthidwa mutatha kugwiritsa ntchito iliyonse.

Machenjezo

Mlingo woyambirira wa Humulin uyenera kusankhidwa molumikizana ndi adokotala. Kuchita mopitirira muyeso kumatha kutsitsa shuga komanso. Chiyero chosakwanira cha mahormoni chimakhala chikuwonekera ndi ma angiopathies osiyanasiyana ndi neuropathy.

Mitundu yosiyanasiyana ya insulin imasiyana mu kuyenera, chifukwa chake muyenera kusintha kuchokera ku Humulin kupita ku mankhwala ena pokhapokha ngati muli ndi mavuto kapena musadzabwezeretse shuga. Kusintha kumafuna kutembenuka kwa mlingo komanso zowonjezera, pafupipafupi kuyang'anira glycemic.

Kufunika kwa insulin kumatha kuwonjezeka kusintha kwa mahomoni m'thupi, ndikumamwa mankhwala ena, matenda opatsirana, kupsinjika. Mahomoni ocheperako amafunikira kwa odwala omwe ali ndi hepatic ndipo, makamaka, kulephera kwa aimpso.

Doctor of Medical Science, Mutu wa Institute of Diabetesology - Tatyana Yakovleva

Ndakhala ndikuphunzira matenda a shuga kwa zaka zambiri. Zimakhala zowopsa anthu ambiri akamwalira, ndipo makamaka amakhala olumala chifukwa cha matenda ashuga.

Ndithamangira kunena mbiri yabwino - Endocrinological Research Center ya Russian Academy of Medical Sayansi yakwanitsa kupanga mankhwala omwe amachiritsa odwala matenda ashuga mellitus. Pakadali pano, kugwiritsa ntchito bwino kwa mankhwalawa kuyandikira 98%.

Nkhani ina yabwino: Unduna wa Zaumoyo wapanga kukhazikitsidwa komwe kumalipirira mtengo wokwera wa mankhwalawo. Ku Russia, odwala matenda ashuga mpaka Marichi 2 nditha kuipeza - Kwa ma ruble 147 okha!

Bongo

Ngati insulin yochulukirapo yagwiritsidwa ntchito kuposa momwe angafunikire kudya chakudya chamafuta, wodwala matenda ashuga adzakumana ndi hypoglycemia. Nthawi zambiri zimayendetsedwa ndi kugwedeza, kuzizira, kufooka, ludzu, thukuta, komanso thukuta lotukwana. Mwa odwala matenda ashuga, Zizindikiro zimachotsedwa, kuchepa kwa shuga kotereku ndizowopsa, chifukwa sizingalephereke pakapita nthawi. Pafupipafupi hypoglycemia ndipo imatha kuwongolera zizindikiro.

Atangoyamba kumene hypoglycemia, imaletseka mosavuta ndi chakudya champhamvu kwambiri - shuga, msuzi wa zipatso, mapiritsi a shuga . Mlingo wamphamvu kwambiri ungayambitse kwambiri hypoglycemia, mpaka isanayambike. Kunyumba, amatha kutha mwachangu ndi kuyambitsa kwa glucagon, pali zida zapadera zothandizira odwala omwe ali ndi matenda a shuga, mwachitsanzo, GlucaGen HypoKit. Ngati malo ogulitsira a shuga m'chiwindi ndi ochepa, mankhwalawa sangathandize. Njira yokhayo yothandiza pamenepa ndi kupaka shuga m'chipatala. Ndikofunikira kupulumutsa wodwalayo posachedwa, chifukwa chikomacho chimakulirakulira msanga ndipo chimavulaza thupi.

Malamulo osungira a Humulin

Mitundu yonse ya insulini imafunikira malo osungirako apadera. Mphamvu za mahomoni zimasintha kwambiri panthawi ya kuzizira, kuwonekera kwa ma radiation ya ultraviolet ndi kutentha pamwamba pa 35 ° C. Soko imasungidwa mufiriji, pakhomo kapena pashelufu kutali ndi khoma lakumbuyo. Moyo wa alumali molingana ndi malangizo ogwiritsira ntchito: zaka zitatu za Humulin NPH ndi M3, zaka 2 kwa Wokhazikika. Botolo lotseguka limatha kutentha kutentha kwa 15-25 ° C kwa masiku 28.

Zotsatira za mankhwala a humulin

Mankhwala amatha kusintha zotsatira za insulin ndikukulitsa chiopsezo cha mavuto. Chifukwa chake, popereka mahomoni, dokotala amayenera kupereka mndandanda wathunthu wa mankhwala omwe atengedwa, kuphatikizapo zitsamba, mavitamini, zowonjezera pazakudya, zowonjezera zamasewera ndi njira zakulera.

Zokhudza thupi	Mndandanda wamankhwala
Kuchuluka kwa shuga, kuwonjezeka kwa insulin Mlingo wofunikira.	Njira zakulera za pakamwa, glucocorticoids, androgens opanga, mahomoni a chithokomiro, kusankha β2-adrenergic agonists, kuphatikiza terbutaline wodziwika bwino ndi salbutamol. Zithandizo za chifuwa chachikulu, nikotini acid, kukonzekera kwa lifiyamu. Thiazide okodzetsa omwe amagwiritsidwa ntchito pochiza matenda oopsa.
Kuchepetsa shuga. Popewa hypoglycemia, mlingo wa Humulin uyenera kuchepetsedwa.	Tetracyclines, salicylates, sulfonamides, anabolics, beta-blockers, hypoglycemic othandizira pochizira matenda amtundu wa 2 shuga. ACE inhibitors (monga enalapril) ndi AT1 receptor blockers (losartan) nthawi zambiri amagwiritsidwa ntchito pochiza matenda oopsa.
Zotsatira zosayembekezereka zamagazi.	Mowa, pentacarinate, clonidine.
Kuchepetsa zizindikiro za hypoglycemia, chifukwa chake zimakhala zovuta kuzimitsa pakapita nthawi.	Beta blockers, mwachitsanzo, metoprolol, propranolol, diso limatsika pochiza glaucoma.

Zomwe zimagwiritsidwa ntchito pa nthawi yapakati

Pofuna kupewa pakati pa nthawi yomwe muli ndi pakati, ndikofunikira kuti muzikhala ndi glycemia wabwinobwino. Mankhwala a Hypoglycemic ndi oletsedwa pakadali pano, chifukwa amalepheretsa kupereka kwa mwana chakudya. Njira yokhayo yovomerezeka pakadali pano ndi ya insulin yayitali komanso yochepa, kuphatikiza Humulin NPH ndi Wokhazikika. Kukhazikitsidwa kwa Humulin M3 sikofunikira, chifukwa sikutha kulipirira bwino shuga.

Pa nthawi yobereka, kufunika kwa mahomoni kumasintha kangapo: kumachepa mu trimester yoyamba, kumawonjezeka kwambiri mu 2 ndi 3, ndipo kumatsika kwambiri pambuyo pobadwa mwana. Chifukwa chake, madokotala onse omwe amayendetsa pakati ndi kubereka ana ayenera kudziwitsidwa za kupezeka kwa matenda ashuga mwa akazi.

Insulin Humulin ingagwiritsidwe ntchito popanda choletsa panthawi yoyamwitsa, popeza sichilowa mkaka komanso sichikhudza shuga la magazi a mwana.

Chingalowe m'malo mwa Humulin insulin ngati zotsatira zoyipa:

Mankhwala	Mtengo wa 1 ml, pakani.		Macheza	Mtengo wa 1 ml, pakani.
	botolo	cholembera		botolo	katoni
Humulin NPH	17	23	Biosulin N	53	73
			Insuman Bazal GT	66	—
			Rinsulin NPH	44	103
			Protafan NM	41	60
Humulin Wokhazikika	17	24	Actrapid NM	39	53
			Rinsulin P	44	89
			Insuman Rapid GT	63	—
			Biosulin P	49	71
17	23	Mikstard 30 nm	Pakadali pano palibe
		Gensulin M30

Tebulo ili limangofanizira mndandanda wathunthu - mwanjira ya anthu opanga majini okhala ndi nthawi yayitali.

Onetsetsani kuti mwaphunzira! Kodi mukuganiza kuti kuyamwa kwa mapiritsi ndi insulini kwa nthawi yonse yokhayo ndi njira yokhayo yothanirana ndi shuga? Sichowona! Mutha kutsimikizira izi nokha ndikuyamba kuzigwiritsa ntchito.

1 ml yankho lili ndi 100 IU ya insulin ya anthu.

Zotsatira za pharmacological

: DNA yobwerezanso insulin yaumunthu. Ndikukonzekera mwachidule insulin.

Choyambitsa chachikulu cha mankhwalawa ndi kuyamwa kwa kagayidwe kazakudya. Kuphatikiza apo, ili ndi anabolic zotsatira. Mu minofu ndi minyewa ina (kupatula ubongo), insulin imayendetsa mofulumira intracellular ya glucose ndi amino acid, imathandizira protein anabolism. Insulin imalimbikitsa kutembenuka kwa glucose kukhala glycogen m'chiwindi, kumalepheretsa gluconeogeneis ndikuthandizira kusintha kwa glucose owonjezera kukhala mafuta.

Makanema okhudzana nawo

Zokhudza mitundu ya insulini yomwe imagwiritsidwa ntchito pochiza matenda a shuga mu kanema:

Kuchokera pazidziwitso zonse zomwe zawonetsedwa m'nkhaniyi, titha kunena kuti kusankha koyenera kwambiri kwa insulin, kuchuluka kwake ndi njira yodulira zimatengera zinthu zingapo. Kuti mudziwe njira yoyenera komanso yotetezeka, muyenera kufunsa katswiri wodziwa za matenda a endocrinologist.

Dzina lachi Latin: humulin nph
Code ya ATX: A10AC01
Chithandizo: insulin yamunthu
Wopanga: Ellie Lilly East, Switzerland
Matchuthi ku pharmacy: mwa mankhwala
Malo osungira: 2-8 madigiri kutentha
Tsiku lotha ntchito: Zaka 2 kuchepetsedwa katoni
- osapitilira milungu 4.

Mankhwala okhala ndi insulin amagwiritsidwa ntchito mu matenda ashuga kuthana ndi vuto la kufooka kwa mahomoni.

Kupanga ndi mafomu omasulira

Mu 1 ml ya chinthu muli magawo 100 a yogwira pophika - insulin ya anthu. Kuphatikiza apo, mankhwalawa akuphatikizapo: phenol, glycerol, zinc oxide, sodium hydrogen phosphate, madzi osalala.

Humulin npc imapezeka ngati kuyimitsidwa, komwe kumayendetsedwa mosakakamiza. Mu phukusi limodzi, 4 kapena 10 ml amagulitsidwa, ndipo makilogalamu 500 ndi ma 3 ml ma cartridge amathandizidwanso m'khitchini, lomwe limagwiritsidwa ntchito mu zolembera.

Kuchiritsa katundu

NPH humulin ali ndi hypoglycemic amatha nthawi yayitali pakanthawi. Izi zimapangidwanso komanso zimapangidwa kuchokera ku DNA ya munthu. The achire zotsatira ndi malamulo a shuga kagayidwe. Mankhwalawa adanenanso katundu wa anabolic. Ili ndi katundu woyendera pokhudzana ndi amino acid m'magulu a minofu, komanso imathandizira mapuloteni anabolism. Mu chiwindi, insulin imasungidwa ndipo glycogen kuchokera ku glucose amasungidwa. Mafuta ochulukirapo amapita m'mafuta amthupi, ndipo kuletsa kwa gluconeogeneis kumachitika.

Pambuyo pa jakisoni wa humulin, mphamvu yogwira mankhwalawa imachitika pambuyo pa ola limodzi ndipo chiwonetsero cha zochita chikugwera panthaka pakati pa maola 2-8. Kutalika kokwanira kwa mankhwalawa kumatha maola 20. Kuchita bwino kwa insulin kumadalira wodwala, kuchuluka kwake kwakuthupi, mlingo ndi malo ena a jakisoni.

Zotsatira zoyipa ndi bongo

Izi zikuphatikiza:

Mawonekedwe amtundu wakhungu (zipsera, zotupa, khungu rede)
Hypoglycemia
Lipodystrophy
Kuyenda thupi lonse
Kupuma pang'ono
Tachycardia
Hyperhidrosis
Kutsika magazi
Kulemera kwa kupuma.

Zizindikiro za mankhwala osokoneza bongo zimaphatikizapo kuwonetsa kuchepa kwa magazi m'magazi: kutsekeka kwa khungu, kumva kwambiri kwa njala, kufooka m'thupi, kunjenjemera, kusokonezeka, kusanza, kuchuluka kwa mtima, ulesi, ndi kuperewera kwa magazi. Digiri yosavuta imayimitsidwa basi - muyenera kudya china chake chokoma kapena jakisoni wa shuga / dextrose. Yapakatikati - jakisoni wa glucagon subcutaneous kapena intramuscularly + chakudya. Wodwala - wodwalayo ali pachiwopsezo chachikulu, atha kudwala matenda ashuga, ndiye muyenera kuyimbira timu ya ambulansi.

Pharmstandard-Ufavita, Russia

Mtengo wapakati - 392 ma ruble pa paketi iliyonse.

Biosulin - analogue yathunthu ya humulin npx, imakhala ndi nthawi yayitali yochita. Palinso biosulin P yogulitsa - mawonekedwe anthawi yochepa a mankhwalawa.

Yotsika mtengo
Chosavuta kugwiritsa ntchito.

Zotsatira zoyipa
Pali mitundu yofanana yopanga yachilendo.

Eli Lilly East, Switzerland

Mtengo wapakati ku Russia - ma ruble 170 phukusi lililonse.

Humulin M3 - amatanthauza ma analogu a magawo awiri, amakhala ndi nthawi yayitali yochitapo kanthu, yomwe imapangitsa kuti ikhale yotetezeka kuposa fanizo lalifupi.

Yotsika mtengo
Kugwiritsa ntchito mosavuta.

Imafunika kugwiritsa ntchito mosamala
Siwothandiza aliyense.

Malangizo omaliza opanga 14.09.2016

Kuyanjana ndi mankhwala ena ndi mitundu ina yoyanjana

Mankhwala ena amakhudza kagayidwe kazakudwala. Dotolo ayenera kudziwitsidwa za chithandizo chirizonse chothandizidwa pamodzi ndi kugwiritsa ntchito insulin ya anthu.

Ngati mukufuna kugwiritsa ntchito mankhwala ena, muyenera kufunsa dokotala.

Kufunika kwa insulin kumatha kuwonjezeka ndikugwiritsa ntchito mankhwala omwe ali ndi zochitika za hyperglycemic, monga njira zakulera zam'mlomo, glucocorticoids, mahomoni a chithokomiro komanso mahomoni okula, danazole, β2-sympathomimetics (mwachitsanzo ritodrin, salbutamol, terbutaline), thiazides.

Kufunika kwa insulin kumatha kuchepa komanso kugwiritsa ntchito mankhwala omwe ali ndi vuto la hypoglycemic, monga mankhwala amkamwa a hypoglycemic, salicylates (mwachitsanzo acetylsalicylic acid), sulfaantibiotic, ma antidepressants (mao inhibitors), ma blocker ena a ACE (Captopril, enalaprilin receptors), blockers , osasankha β-blockers kapena mowa.

Somatostatin analogues (octreotide, lanreotide) atha kuwonjezera komanso kufooketsa kufunika kwa insulin.

Kutulutsa mawonekedwe, kapangidwe kake ndi ma CD

Ikupezeka onse ngati mtundu wa kuyimitsidwa kwa kayendetsedwe ka ma subcutaneous mu mbale ("Humulin" NPH ndi MZ), komanso mawonekedwe a makatoni okhala ndi cholembera (“Humulin Regular”). Kuyimitsidwa kwa oyang'anira sc kumamasulidwa mu 10 ml. Mtundu wa kuyimitsidwa ndi mitambo kapena milky, voliyumu ya 100 IU / ml mu cholembera cha 1.5 kapena 3 ml. M'katoni, masipikendi 5 a pulasitiki.

Kuphatikizikako kumaphatikizapo insulin (yaumunthu kapena ya biphasic, 100 IU / ml), zotuluka: metacresol, glycerol, protamine sulfate, phenol, zinc oxide, sodium hydrogen phosphate, madzi a jakisoni.

Opanga INN

Dzinalo lapadziko lonse lapansi ndi insulin-isophan (umisiri wa chibadwa cha anthu).

Imapangidwa makamaka ndi Lilly France SAAS, France.

Zoyimira ku Russia: "Eli Lilly Vostok S.A."

"Humulin" imasiyana pamtengo malinga ndi mtundu wa kumasulidwa: mabotolo kuchokera ku ma ruble 300-500, makatoni kuchokera ku ruble 800-1000. Mtengo ungasiyane m'mizinda yosiyanasiyana.

Pharmacokinetics

Mlingo wa mawonetseredwe amathandizidwe umadalira malo a jakisoni, mlingo womwe umayendetsedwa ndi mankhwala osankhidwa. Imagawidwa mosiyanasiyana munsiyo, simalowerera mkaka wa m'mawere ndi placenta. Imawonongeka makamaka mu impso ndi chiwindi ndi enzyme insulinase, yomwe imatsitsidwa ndi impso.

Mtundu wodwala matenda a shuga.
Mimba mwa odwala omwe ali ndi matenda ashuga oopsa (okhala ndi vuto la kudya).

Malangizo ogwiritsira ntchito (mlingo)

Dokotala amakhazikitsa mlingo, kutengera mtundu wa glycemia malinga ndi zotsatira za mayeso. Amathandizidwa mosavuta kapena m'njira zamitsempha 1-2 patsiku. Masamba obayira ndi am'mimba, matako, mapewa, kapena m'chiuno. Popewa lipodystrophy, muyenera kusintha malowa nthawi zonse kuti asabwerezenso kangapo pamwezi.

Sizoletsedwa kupatsa Humulin m'mitsempha!

Pambuyo pa jekeseni, khungu silingasunthe. Pewani kulowa m'mitsempha yamagazi kuti hematoma isapangidwe. Wodwala aliyense ayenera kuphunzitsidwa ndi dokotala kapena namwino pakayendetsedwe koyenera ka mankhwala ndi chitetezo.

Humulin ndi chiyani?

Masiku ano, mawu akuti Humulin amatha kuwoneka mu mayina a mankhwala angapo omwe amapangidwa kuti achepetse shuga ya magazi - Humulin NPH, MoH, pafupipafupi komanso Ultralent.

Kusiyana kwa njira zopangira mankhwalawa kumapereka mawonekedwe aliwonse ochepetsa shuga ndi zomwe ali nazo. Izi zimazindikiridwa popereka mankhwala kwa anthu odwala matenda ashuga. Mankhwala, kuphatikiza insulin (gawo lalikulu, loyesedwa mu IU), zinthu zothandizira zilipo, izi zitha kukhala zosalimba zamadzimadzi, ma protein, carbolic acid, metacresol, zinc oxide, sodium hydroxide, etc.

Horoni ya pancreatic imayikidwa m'makalata, mbale, ndi zolembera. Malangizo omwe aphatikizidwa amadziwitsa za zomwe amagwiritsidwa ntchito ngati mankhwala a anthu. Musanagwiritse ntchito, makatoni ndi mbale siziyenera kugwedezeka mwamphamvu; Choyenera kwambiri chogwiritsidwa ntchito ndi odwala matenda ashuga ndi cholembera.

Kugwiritsa ntchito mankhwala omwe atchulidwa kumathandizira kuti zitheke kupeza chithandizo chokwanira kwa odwala omwe ali ndi matenda ashuga, chifukwa amathandizira kuti pakhale kuperewera kwathunthu komanso kuperewera kwa mphamvu ya amkati amkati. Fotokozerani Himulin (mlingo, regimen) ayenera kukhala wa endocrinologist. M'tsogolo, ngati pakufunika kutero, dokotala yemwe akukonzekera akhoza kuwongolera njira yochizira.

Mu matenda a shuga a mtundu woyamba, insulin imaperekedwa kwa munthu moyo wonse. Ndi zovuta za mtundu wa 2 shuga, zomwe zimayendera limodzi ndi matenda amtundu wa concomitant, mankhwalawa amapangidwa kuchokera ku maphunziro osiyanasiyana. Ndikofunika kukumbukira kuti ndi matenda omwe amafunikira kukhazikitsa mahomoni opanga thupi m'thupi, simungakane mankhwala a insulini, apo ayi mavuto akulu sangathe kupewedwa.

Mtengo wa mankhwalawa gulu lama pharmacological zimatengera nthawi yochitapo ndi mtundu wa ma CD. Mtengo wowerengeka m'mabotolo umayambira ku ma ruble 500., mtengo wake m'matotolo - kuchokera ku ma ruble 1000., M'mapensulo a syringe ndi osachepera 1500 rubles.

Kuti mudziwe mlingo ndi nthawi ya kumwa mankhwalawa, muyenera kulumikizana ndi endocrinologist

Kuyanjana kwa mankhwala osokoneza bongo

Zochita za Humulin zimalimbikitsa:

mapiritsi ochepetsa shuga,
zoletsa za MAO, ACE, kaboni anhydrase,
imidazoles
anabolic steroids
antidepressants - monoamine oxidase inhibitors,
tetracycline mankhwala opha tizilombo,
Mavitamini B,
Kukonzekera kwa lifiyamu
Hypotonic mankhwala ochokera pagulu la ACE zoletsa ndi beta blockers,
theofylline.

Mankhwala omwe molumikizana nawo osavomerezeka:

mapiritsi olembera
ma analcics
calcium blockers,
mahomoni a chithokomiro,
glucocorticosteroids,
okodzetsa
mankhwala antidepressants,
yambitsa zochitika zachisoni zamanjenje.

Zonsezi zimalepheretsa zotsatira za "Humulin", zimafooketsa mphamvu zake. Amaletsedwanso kugwiritsa ntchito mitundu ina ya mankhwala.

Mimba komanso kuyamwa

Ndikofunikira kudziwitsa adokotala za kukonzekera kukhala ndi pakati kapena kutha kwake. Izi zikufunika kukonza mankhwalawo. Kufunika kwa insulin kwa odwala matendawa omwe ali ndi matenda ashuga nthawi zambiri kumachepetsedwa mu trimester yoyamba, koma kumawonjezeka kwachiwiri komanso kwachitatu. Pa mkaka wa m`mawere, chithandizo ndi kusintha zakudya zimafunikanso. Pazonse, Humulin sanawonetse mutagenic mu mayeso onse, choncho chithandizo cha amayi ndi chothandiza kwa mwana.

Biosulin kapena mwachangu: chabwino ndi chiti?

Izi ndi zinthu zomwe zimapezeka panjira ya biosynthetic (DNA recombinant) chifukwa cha kusintha kwa enzymatic kwa porcine insulin. Ali pafupi kwambiri ndi insulin yaumunthu. Onse ali ndi zotsatira zakanthawi kochepa, chifukwa chake nkovuta kunena kuti wabwino ndi uti. Chisankho pazakusankhidwa chimachitika ndi katswiri.

Fananizani ndi fanizo

Kuti mumve mankhwala omwe ndi oyenera kugwiritsa ntchito, lingalirani za analogues.

Kupanga: Novo Nordisk A / S Novo-Alle, DK-2880 Baggswerd, Denmark.

Mtengo: yankho kuchokera ku ma ruble 370, ma cartridge kuchokera ku 800 rubles.

Zochita: hypoglycemic wothandizira wa nthawi yayitali.

Ubwino: zochepa zotsutsana ndi zoyipa zochepa, zoyenera kwa amayi apakati komanso oyamwitsa.

Sangagwiritsidwe ntchito molumikizana ndi thiazolidinediones, popeza pali chiopsezo cholephera kwamtima, komanso choperekedwa ndi intramuscularly, pokhapokha.

. Chithandizo chogwira ntchito: insulin yaumunthu.

Wopanga: "Novo Nordisk A / S Novo-Alle, DK-2880" Baggswerd, Denmark.

Mtengo: yankho kuchokera ku ma ruble 390, makatoni - kuchokera ku ruble 800.

Zochita: hypoglycemic chinthu chaifupi.

Ubwino: Woyenera kwa ana ndi achinyamata, amayi oyembekezera komanso oyembekezera, amatha kuperekedwako mosadukiza kapena mwaubongo, wosavuta kugwiritsa ntchito kunja kwa nyumba.

Zitha kugwiritsidwa ntchito ndi zinthu zogwirizana, sizingagwiritsidwe ntchito limodzi ndi thiazolidatediones.

Cholinga chilichonse cha analogue chikuyenera kuvomerezedwa ndi katswiri. Dokotala wokhawo amene akupezekapo, potengera zotsatira za mayeso, ndi omwe amasankha kuti asinthe mankhwalawo kukhala wodwala. Kugwiritsa ntchito palokha insulin zina ndizoletsedwa!

Mikhalidwe yapadera

1 ml ya insulin ya anthu 100 IU Othandizira: metacresol, glycerol (glycerin), madzi phenol, protamine sulfate, sodium hydrogen phosphate, zinc oxide, madzi d / a, hydrochloric acid (10% yankho) ndi / kapena sodium hydroxide (10% yankho) kupanga pH yofunikira. human insulin 100 IU Excipients: metacresol, glycerol (glycerin), madzi phenol, protamine sulfate, sodium hydrogen phosphate, zinc oxide, madzi d / i, hydrochloric acid (10% yankho) ndi / kapena sodium hydroxide (10% yankho) kuti apange kuchuluka kwa pH. insulin-isophan (umisiri wa chibadwa cha anthu) 100 IU Othandizira: metacresol - 1.6 mg, glycerol - 16 mg, phenol - 0,65 mg, protamine sulfate - 0,348 mg, sodium hydrogen phosphate heptahydrate - 3,78 mg, zinc oxide - q.s. kuti mupeze Zn2 + osaposa 0,04 mg, madzi d / i - mpaka 1 ml, hydrochloric acid solution 10% - q.s. kuti pH 6.9-7.8, sodium hydroxide solution 10% - q.s. mpaka p 6.9-7.8.

Humulin NPH mavuto

Zotsatira zoyipa zomwe zimakhudzana ndi zotsatira zazikulu za mankhwalawa: hypoglycemia. Hypoglycemia yamphamvu imatha kubweretsa kusokonezeka kwa chikumbumtima ndipo (makamaka zikachitika) kufa. Thupi lawo siligwirizana: zimachitika matupi awo sagwirizana - hyperemia, kutupa kapena kuyunkhira pamalo a jekeseni (nthawi zambiri amayima patadutsa masiku angapo mpaka masabata angapo), zotsatira zoyipa zamkati (zimachitika kangapo, koma zimakhala zowopsa) - kuyamwa pang'ono, kufupika, kupuma pang'ono , kuchepa kwa magazi, kuchuluka kwa mtima, kuchuluka thukuta. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo. Zina: mwayi wokhala ndi lipodystrophy ndizochepa.

Zizindikiro zamagwiritsidwe ntchito ndi zoyipa

Shuga mellitus, momwe insulin tikulimbikitsidwa.
(matenda ashuga).

Kukhazikika hypoglycemia.
Hypersensitivity.

Nthawi zambiri pa mankhwala akukonzekera insulin, kuphatikiza Humulin M3, kukula kwa hypoglycemia kumawonedwa. Ngati ili ndi mawonekedwe owopsa, imatha kudzutsa chikumbumtima cha hypoglycemic (kuponderezana ndi kusazindikira) ngakhale kupangitsa kuti wodwalayo afe.

Mwa odwala ena, thupi lawo siligwirizana, kuwoneka pakuluma pakhungu, kutupa ndi kufupika kwa malo a jakisoni. Nthawi zambiri, matendawa amadzidzidzikira okha patatha masiku kapena milungu yochepa atayamba chithandizo.

Nthawi zina izi sizimalumikizana ndi kugwiritsa ntchito mankhwalawo pawokha, koma ndi chifukwa cha mphamvu ya zinthu zakunja kapena jakisoni wolakwika.

Pali ziwonetsero zomwe sizigwirizana ndi zachilengedwe. Amachitika kawirikawiri, koma zowopsa. Ndi malingaliro otere, zotsatirazi zimachitika:

kuvutika kupuma
kuyamwa kofananira
kugunda kwa mtima
dontho mu kuthamanga kwa magazi
kupuma movutikira
thukuta kwambiri.

Milandu yoopsa kwambiri, chifuwa chimatha kusokoneza moyo wa wodwalayo ndipo imafunikira chithandizo chamankhwala mwadzidzidzi. Nthawi zina insulin m'malo kapena desensitization chofunika.

Mukamagwiritsa ntchito insulin ya nyama, kukana, hypersensitivity kwa mankhwala, kapena lipodystrophy imayamba. Mukamapereka insulin Humulin M3, kuthekera kwa zotulukazi ndi pafupifupi zero.

Makulidwe a insulin

Kuti mupeze jakisoni moyenera mankhwalawo, muyenera kuchita njira zina zoyambirira. Choyamba muyenera kudziwa malo omwe jakisoniyo, sambani manja anu ndikupukuta malowa ndi nsalu yothinidwa ndimowa.

Kenako muyenera kuchotsa kapu yoteteza ku singano ya syringe, kukonza khungu (kutambasula kapena kutsina), ikani singano ndikupanga jakisoni. Kenako singano iyenera kuchotsedwa ndipo masekondi angapo, osafunikira, kanikizani tsamba la jekeseni ndi chopukutira. Pambuyo pake, mothandizidwa ndi kapu yakunja yoteteza, muyenera kumasula singano, kuichotsa ndikubwezeranso chipewa pa syringe.

Simungagwiritse ntchito singano yemweyo ya syringe kawiri. Vial kapena cartridge imagwiritsidwa ntchito mpaka itapanda kanthu, ndiye kuti imatayidwa. Ma cholembera a syringe adapangira kuti azigwiritsa ntchito payekha.

Migwirizano yogulitsa, yosungirako

Humulin M3 NPH imapezeka pa pharmacy pokhapokha ngati mwalandira mankhwala.

Mankhwalawa amayenera kusungidwa pamtunda wa madigiri 2 mpaka 8, sangathe kuwundana ndikuwonetsa kuwala kwa dzuwa ndi kutentha.

Vial yotsegulidwa ya NPH imatha kusungidwa pamtunda wa 15 mpaka 25 digiri masiku 28.

Kutengera ndi kutentha kofunikira, kukonzekera kwa NPH kumasungidwa zaka 3.

Mimba komanso kuyamwa

Ngati mayi woyembekezera ali ndi matenda ashuga, ndiye kuti ndikofunikira kwambiri kuti azilamulira glycemia. Pakadali pano, zofuna za insulin nthawi zambiri zimasintha nthawi zosiyanasiyana. Mu trimester yoyamba, imagwera, ndipo chachiwiri ndi chachitatu chikuwonjezeka, kotero kusintha kwa mankhwalawa kungakhale kofunikira.

Kwa odwala matenda ashuga ambiri, mankhwala okhala ndi insulin ndiwo maziko a mankhwalawa komanso chitsimikizo cha thanzi labwino.

Mankhwalawa akuphatikizapo Humulin NPH. Muyenera kudziwa zazikulu za chida ichi kuti mupewe zolakwika pakugwiritsa ntchito kwake. Wopanga izi amapezeka ku Switzerland.

Odwala Apadera ndi Mayendedwe

Popereka Humulin, adokotala ayenera kuganizira kuti odwala ena amafunikira chithandizo chapadera. Thupi lawo, mankhwalawa amatha kuthana ndi vuto ngati simukuwonetsa kuchenjera.

Izi zikugwiranso ntchito kwa odwala monga:

Amayi oyembekezera. Mankhwala awo ndi mankhwalawa amaloledwa, chifukwa insulini siyivulaza kukula kwa mwana wosabadwayo ndipo sikuti kuphwanya njira yoyembekezera. Koma pakadali pano, azimayi amadziwika ndi kusintha kwakuthwa kwa zizindikiro za shuga, ndichifukwa chake kusinthika kwakukulu pamlingo wofuna thupi la insulin ndikotheka. Kulephera kuyendetsa bwino kungayambitse bongo ndipo, zomwe zimakhala zowopsa kwa mayi woyembekezera komanso mwana. Chifukwa chake, ndikofunikira kuyang'ana kuchuluka kwa shuga m'mimba yonse.
Amayi adayamwitsidwa. Amaloledwa kugwiritsa ntchito Humulin. Zomwe zimagwiritsidwa ntchito sizikhudza mtundu wa mkaka wa m'mawere ndipo sizowopseza khanda. Koma muyenera kuwonetsetsa kuti mzimayi amatsata chakudya.
Ana. Ngati muli ndi matenda ashuga ali ana, mutha kugwiritsa ntchito mankhwala okhala ndi insulin. Koma muyenera kuganizira za zomwe zimachitika mthupi, chifukwa chake muyenera kusankha mlingo wa mankhwalawa.
Anthu okalamba. Amakhalanso ndi zochitika zokhudzana ndi zaka zomwe zimadaliridwira kuti musamalire mukamapereka Humulin ndikusankha dongosolo la mankhwalawa. Koma ndi njira yoyenera, mankhwalawa samavulaza odwala.

Izi zikutanthauza kuti kuti muthandizidwe ndi insulini muyenera kuyang'aniridwa ndi dokotala nthawi zonse ndikuzindikira zinthu zonse zomwe zingakhudze thanzi.

Chofunikira popereka mankhwala ndikuti mupeze matenda omwe amadziwika ndi odwala kuwonjezera pa matenda a shuga. Chifukwa cha iwo, kusintha kwa dongosolo la mankhwala ndi kusintha kwa mankhwala kungafunike.

Izi zikugwiranso ntchito pa milandu yotsatirayi:

Kukhalapo kwa kulephera kwa impso. Chifukwa cha ichi, kufunikira kwa insulini kumakhala kotsika kuposa zovuta zotere. Izi zikutanthauza kuti odwala matenda ashuga omwe ali ndi vuto la impso amakhala ndi mankhwala ochepetsera.
Kulephera kwa chiwindi. Ndi matenda awa, kuthekera kwa Humulin pamthupi kungakhale. Mwakutero, madokotala amayesetsa kuchepetsa kuchuluka kwa mankhwalawa.

Chifukwa cha Humulin, palibe mavuto okhudzana ndi chidwi ndi chidwi, motero zochitika zilizonse zimaloledwa pa chithandizo cha mankhwalawa. Chenjezo liyenera kuchitika pamene hypoglycemia ichitika, chifukwa chovuta m'derali. Izi zimatha kutenga chiwopsezo chovulala mukamachita zoopsa ndikupanga ngozi zoyendetsa.

Mndandanda wazofananira

Tcherani khutu! Mndandandandawu umakhala ndi mawu ofanana a Humulin Regular, omwe ali ndi mawonekedwe ofanana, kotero mutha kusankha nokha m'malo mwake, mukuganizira mawonekedwe ndi mankhwalawa a mankhwalawa omwe adokotala adawauza. Perekani zokonda kwa opanga ku USA, Japan, Western Europe, komanso makampani odziwika bwino ochokera ku Eastern Europe: Krka, Gideon Richter, Actavis, Aegis, Lek, Hexal, Teva, Zentiva.

Kutulutsa Fomu (mwa kutchuka)	Mtengo, pakani.
Humulin Wokhazikika
Mbale za 100 IU / ml, 10 ml (Eli Lilly, USA)	157
Cartridges 100 IU / ml, 3 ml, ma PC 5. (Eli Lilly, USA)	345
Khalid
Actrapid NM, Mbale za 100 IU / ml, 10 ml	405
NM penfill, makatoni 100 IU / ml, 3 ml, ma PC 5.	823
Actrapid HM
Actrapid HM Penfill
Biosulin P
Kuyimitsidwa kwa theka-chikopa int. 100 IU / ml botolo 10 ml 1 pc., Pack. (Pharmstandard - Ufavita, Russia)	442
Kuyimitsidwa kwa nusu-chikopa int. 100 IU / ml cartridge 3 ml 5 ma PC., Pack. (Pharmstandard - Ufavita, Russia)	958
Kuyimitsidwa kwa theka la chikopa. 100 IU / ml cartridge + syringe - cholembera cha Biomatic Pen2 3 ml 5 ma PC., Pack. (Pharmstandard - Ufavita, Russia)	1276
Vozulim R
Gansulin r
Gensulin r
Ma genulin amene amapanga ma * insulin *
Insulin yamunthu
Insulin yamunthu
Majini amapanga insulin
Kuphatikizanso insulin yaumunthu
Insuman Rapid GT
100ME / ml 3ml No. 1 syringe - cholembera cha SoloStar (Sanofi - Aventis Vostok ZAO (Russia)	1343.30
Insuran P
Monoinsulin CR
Kubwezeretsanso Insulin ya Anthu
Rinsulin P
Njira yothetsera jakisoni 100 IU / ml 10 ml - botolo (paketi ya makatoni) (GEROPHARM - Bio LLC (Russia)	420
Njira yothetsera jakisoni 100 IU / ml (katoni) 3 ml No. 5 (paketi ya makatoni) (GEROPHARM - Bio LLC (Russia)	980
ROSINSULIN
Rosinsulin P
Humodar R 100 Mitsinje
Humulin ™ Wokhazikika

Alendo asanu ndi anayi adapereka lipoti la kudya tsiku lililonse

Kodi ndiyenera kumwa Humulin pafupipafupi kangati?
Ambiri omwe amayankhidwa nthawi zambiri amamwa mankhwalawa katatu patsiku. Ripotilo likuwonetsa kuti anthu ena omwe amayankha mankhwalawa amamwa mankhwalawa kangati.