Malangizo ogwiritsira ntchito mankhwala osokoneza bongo, analogi, ndemanga

Amagwiritsidwa ntchito pochiza mitundu yonse ya matenda ashuga. Perekani kwa amayi apakati, ngati chithandizo cha zakudya sichinapereke zotsatira, komanso pambuyo pobala. Kubwezeretsanso insulin ya anthu kumathandizanso pakuchita opareshoni, kuvulala, matenda opatsirana, omwe amatsatiridwa ndi malungo.

Ndi dokotala yekhayo amene angatchule mlingo wa momwe mankhwalawo amathandizira, chifukwa muzochitika zonsezi zimatengera mawonekedwe amodzi a matendawa.

Nthawi zambiri, jakisoni amachitika mosadukiza, mphindi 15-30 asanadye. Mutha kuyambanso kudzera m'mitsempha yambiri. Chiwerengero chovomerezeka cha jakisoni ndi katatu pa tsiku. Nthawi yomweyo jakisoni isanachitike, muyenera kuwonetsetsa kuti botolo lomwe lili ndi mankhwalawo likuthiramo kutentha kwa m'chipindacho, ndipo madzi amene ali mkati mwake ndi osadetsedwa. Kugwiritsa ntchito mankhwalawa ndi mitundu yonse ya ma opacities sikovomerezeka.

Kusintha kwa mlingo wa insulin kumachitika ngati kuphwanya thupi la munthu, ngati wapezeka:

• matenda opatsirana
• mavuto a chithokomiro
• Matenda a Addison
• hypopituitarism,
• shuga mu anthu opitilira zaka 65.

Miyezi ya glucose imatha kutsika kwambiri pazifukwa zotsatirazi:

• kusintha kwa jakisoni,
• mankhwala osokoneza bongo
• zolimbitsa thupi
• mavuto ndi m'mimba;
• momwe mankhwalawa amaphatikizira,
• posamutsa wodwala ku insulin yaumunthu.

Bwererani ku tebulo la zamkati

Ndinkakonda (kuchokera ku Chilatini - insulin solution) ili ndi dzina lina. Zimatengera kutalika kwazinthu ndi kapangidwe kake. Kupeza insulin yaumunthu kumachitika mwangozi, pogwiritsa ntchito ma genetic engineering. Izi zimazindikira kutalika kwake. Palinso chinthu - ma insulin ya magawo awiri, yokhala ndi nthawi yosiyanasiyana yowonetsera. Magulu otsatirawa a mankhwala amadziwika:

Kutulutsa kwakanthawi Mbali zokhudzana ndi zinafotokozedwe za mankhwala osakhalitsa Zizindikiro zoyambirira zimawonekera patatha mphindi 30 kuchokera kukonzekera kwa Humulin, Rinsulin, kukhudzana kwa Gansulin kumayamba patangopita maola awiri ndi atatu, Insuran Bioinsulin Medium Zochita Zizindikiro zimayamba mkati mwa ola limodzi, mawonetseredwe atatha - maola 6.7 "Boisulin" "Protafan" Pambuyo maola 12, "Insuman" imachotsedwa kwathunthu kwa thupi. inshuwaransi yamagawo awiri. Kutha kusintha nthawi yayitali yogwira thupi la "Gansulin" "Gensulin" Kulandila kumagwirizana mwachindunji ndi chakudya "Mikstard" Ikani kawiri pa tsiku, mphindi 30 musanadye chakudya

Kuchepetsa shuga m'magazi, hypersensitivity ndi njira zokhazo zomwe zimagwiritsa ntchito insulin. Zotsatira zoyipa ndi chifuwa, mu mawonekedwe a urticaria, hypoglycemia. Mutha kuyang'ananso:

• hypoglycemic coma,
• zovuta zamanjenje ndi mtima dongosolo,
• mavuto ndi malankhulidwe ndi masomphenya,
• chisokonezo,
• hyperglycemia
• Kutupa pa malo a jekeseni.

Bwererani ku tebulo la zamkati

Insulin yaumunthu (genetic engineering) sigwirizana ndi mankhwala ena. Mankhwala a Sulfanilamide ndi steroid, komanso ma tetracyclines, theophylline, quinidine, quinine, ethanol, amachepetsa kuchuluka kwa shuga m'magazi. M'malo mwake, zomwe zili mkati zimachulukitsa: diuretics, mahomoni a chithokomiro, antidepressants, chamba, chikonga, epinephrine, kulera kwamlomo.

Nkhani ya m'modzi wa owerenga athu, Inga Eremina:

Kulemera kwanga kunali kovutitsa, ndimalemera ngati 3 sumo wrestler ophatikizidwa, omwe ndi 92kg.

Momwe mungachotsere kulemera kwathunthu? Kodi mungathane ndi kusintha kwa mahomoni ndi kunenepa kwambiri? Koma palibe chomwe chimasokoneza kapena chinyamata kwa munthu monga kuchuluka kwake.

Koma chochita kuti muchepetse kunenepa? Opaleshoni ya laser liposuction? Ndinazindikira - osachepera 5000 dollars. Njira zama Hardware - kutikita minofu ya LPG, cavitation, kukweza kwa RF, myostimulation? Zotsika mtengo zochepa - maphunzirowa amatenga ndalama zokwana ma ruble 80,000 ndi katswiri wazakudya zothandizira. Mutha kuyesa kuthamanga, mpaka kumisala.

Ndipo kupeza nthawi yonseyi? Inde komanso okwera mtengo kwambiri. Makamaka tsopano. Chifukwa chake, ndekha, ndidasankha njira ina.

Pakakhala mankhwala osokoneza bongo ambiri, munthu amamva njala, mutu, kugwedezeka, kuthamanga kwa magazi kumachepa. Wodwalayo amakhala ngati wagona. Poyamba matendawa, munthu amadzichotsera yekha izi. Ndikokwanira kudya zakudya zambiri zokhala ndi shuga, kumwa madzi okoma a kaboni. Ngati muli ndi mankhwalawa "Glucagon" m'manja, perekani jakisoni.

Kugwirizana kwa insulin sungunuka anthu chibadwa mankhwala zina zinthu

Ndi mankhwala osokoneza bongo, hypoglycemia imayamba (thukuta lozizira, kufooka, kufooka kwa khungu, kunjenjemera, malovu, mantha, kupweteka kwa miyendo, manja, lilime, milomo, njala, kupweteka mutu), kukokana, hypoglycemic chikomokere. Chithandizo: wodwalayo amatha kuthetsa vuto lokhala ndi matenda ofewa pogwiritsa ntchito chakudya kapena shuga. Glucagon imayendetsedwa mobwerezabwereza, kudzera m'mitsempha, kapena mu mnofu, kapena kuperewera kwa magazi, imaperekedwa kudzera m'mitsempha, ndi hypoglycemic coma, 20-40 ml (mpaka 100 ml) yankho la dextrose 40% limalowetsedwa kudzera m'mitsempha mpaka wodwalayo atasiya kukomoka.

Dzinalo Lopanda Malire (Zothandizira Zothandiza):

Jekeseni wa 3 ml - makatoni amtundu wamagalasi osavala (5) - ma CD a ma CD (1) - ma CD.

Mankhwala tikulimbikitsidwa kugwiritsa ntchito zotsatirazi:

- wodwala matenda a shuga ogwirizana ndi insulin (mtundu 1),

- osagwirizana ndi insulin - wodwala matenda a shuga (mtundu 2): gawo la kukana kwa othandizira am'magazi a hypoglycemic, kukana pang'ono kwa mankhwalawa (panthawi yophatikiza mankhwala), ndi matenda omwe amagwirizana, kugwira ntchito, komanso mimba.

Mankhwala

Ma insulin okhala ndi chibadwa chaumunthu ndi kukonzekera kwanthaŵi yochepa. Kuchita ndi cholandilira chapadera chamkati mwa maselo, mankhwalawo amapanga zovuta za insulin. Mwa kuwonjezera kupanga kwa cAMP (m'maselo a chiwindi ndi maselo amafuta) kapena kulowa mwachindunji mu cell, izi zimapangitsa kuti machitidwewo akhale mkati mwa selo, kuphatikiza mapangidwe ena a ma enzymes ofunikira (pyruvate kinase, hexokinase, glycogen synthetase ndi ena). Kutsika kwa shuga m'magazi kumachitika chifukwa cha kuchuluka kwa mayamwidwe ndikumayamwa ndi zimakhala, kuwonjezeka kwa mayendedwe amkati, kukondoweza kwa glycogenogenesis, lipogenesis, kaphatikizidwe ka mapuloteni, kuchepa kwa kuchuluka kwa shuga ndi chiwindi ndi njira zina. Mothandizidwa ndi subcutaneally, mphamvu ya mankhwalawa imayamba pambuyo pa mphindi 20 mpaka 30, ndipo imakhala yotalikirapo patatha maola 1 mpaka 3 ndipo imatha maola 5 mpaka 8 (kutengera mlingo). Kutalika kwa mankhwalawa kumatengera malo ndi njira yoyendetsedwera, mlingo ndipo walankhula machitidwe ake. Kukwanira kwathunthu kwa mankhwalawa kumatengera mlingo, malo a jakisoni (ntchafu, pamimba, matako), njira yoyendetsera (subcutaneous, intramuscularly), mulingo wa insulin mu mankhwala, ndi zina. Mu minofu, mankhwalawa amagawidwa mosiyanasiyana. Simalowa mkaka wa m'mawere kudzera mu zotchinga. Makamaka impso ndi chiwindi, zimawonongedwa ndi insulinase. Kutha kwa theka-moyo kumapanga kuyambira mphindi zingapo mpaka 10. 30 - 80% imachotsa impso.

Type 2 shuga mellitus (gawo la kukana mankhwalawa am'kamwa hypoglycemic, mankhwala osakanikirana), mtundu 1 wa matenda ashuga, hyperosmolar ndi ketoacidotic chikomokere, matenda ashuga ketoacidosis, matenda osokoneza bongo omwe amapezeka panthawi yapakati (ngati zakudya sizothandiza) ntchito pang'onopang'ono kwa odwala omwe ali ndi matenda ashuga omwe ali ndi matenda oopsa, ovulala akubwera, njira zopangira opaleshoni, kubereka, ndi kagayidwe kachakudya matenda, musanafike mankhwala ndi kukonzekera insulin kukonzekera.

Njira yogwiritsira ntchito insulin sungunuka waumunthu wopanga ndi ma doys

Njira yoyendetsera ndi mtundu wa mankhwalawa imakhazikitsidwa payekhapayekha, munthawi iliyonse, malinga ndi kuchuluka kwa shuga m'magazi asanafike komanso 1 mpaka 2 maola atatha kudya, komanso kutengera mawonekedwe a pathology ndi kuchuluka kwa glucosuria. Mankhwalawa kutumikiridwa kwa mphindi 15-30 asanadye chakudya mosadukiza (njira yodziwika bwino yoyendetsera), kudzera m'mitsempha, kudzera m'mitsempha. Ndi matenda a shuga, matenda ashuga ketoacidosis, opaleshoni, mwamitsempha komanso m'mitsempha. Pafupipafupi makonzedwe a mankhwala pa monotherapy nthawi zambiri 3 pa tsiku (mwina mpaka 5-6 pa tsiku, ngati pangafunike). Popewa kukula kwa lipodystrophy (hypertrophy kapena atrophy yama subcutaneous mafuta), tsamba la jekeseni liyenera kusintha nthawi iliyonse. Piritsi tsiku lililonse ndi 30- 40 PISCES, kwa ana - 8 PISCES, ndiye kuti muyezo wa tsiku ndi tsiku - 0.5-1 PIERES / kg kapena 30- 40 PIECES katatu patsiku, mwina mpaka 5-6 pa tsiku. ngati kuli kotheka. Ngati mlingo wa tsiku ndi tsiku umaposa 0,6 U / kg, ndiye kuti insulini iyenera kutumikiridwa monga ma jakisoni a 2 kapena kuposeranso mbali zosiyanasiyana za thupi. Kuphatikiza komwe kumatheka ndi ma insulin omwe amakhala nthawi yayitali. Choyimira chopukutira chinapukutidwa ndi Mowa pambuyo pakuchotsa kapu ya aluminiyamu kutipyoza ndi singano yosalala ndipo njira ya insulin imatengedwa kuchokera ku vial.

Onetsetsani kuti mwayang'anitsitsa vutoli musanatenge insulini kuchokera ku vial. Mankhwalawa sangathe kugwiritsidwa ntchito pakuwombera, kuwoneka kwa matupi akunja, kuchuluka kwa zinthu pagalasi ya botolo. Kutentha kwa mankhwala omwe amagwiritsidwa ntchito kuyenera kufanana ndi kutentha kwa chipinda. M'matenda opatsirana, matenda a chithokomiro operewera, hypopituitarism, matenda a Addison, matenda a shuga ndi anthu opitilira 65 komanso kulephera kwaimpso, ndikofunikira kusintha mlingo wa insulin. Zomwe zimayambitsa kukula kwa hypoglycemia zimatha kukhala: kuthana ndi mankhwala, kuchuluka kwa insulin, kudumpha chakudya, kutsekula m'mimba, kusanza, kupsinjika kwa malo, jakisoni, ntchafu, phewa, matenda omwe amachepetsa kufunika kwa insulin (matenda apamwamba a chiwindi ndi impso, ndipo komanso hypofunction ya pituitary gland, adrenal cortex kapena chithokomiro England, mogwirizana ndi mankhwala ena. Ndikotheka kuchepetsa kuchuluka kwa shuga m'magazi mukachotsa wodwala kuchokera ku insulin ya nyama kupita ku insulin ya anthu. Kusamutsa wodwala kupita ku insulin yaumunthu kuyenera kuchitika kokha moyang'aniridwa ndi dokotala ndipo nthawi zonse kumayenera kukhala kovomerezeka. Chizolowezi cha hypoglycemia chimatha kudodometsa kuthekera kwa odwala kuti azigwiritsa ntchito makina ndi makina, komanso kuchita nawo nawo magalimoto ambiri. Odwala omwe ali ndi matenda ashuga amatha kudzichiritsa okha hypoglycemia pakudya shuga kapena zakudya zopatsa thanzi (ndizabwino kukhala ndi shuga pafupifupi 20 g). Kuti athane ndi vuto la kukonza mankhwalawa, ndikofunikira kudziwitsa adotolo za hypoglycemia wakale. Mukamagwiritsa ntchito insulin yocheperako nthawi zina, kuwonjezereka kapena kuchepa kwa kuchuluka kwa minyewa ya adipose pamalo jakisoni ndikotheka. Mwa kusintha malo a jakisoni nthawi zonse, lipodystrophy imatha kupewedwa. Pa nthawi ya pakati, ndikofunikira kuganizira kuchepa (mu 1 trimester) kapena kuwonjezeka (mu 2nd ndi 3 trimesters) pazofunikira za insulin. Kufunika kwa insulini kumatha kuchepa kwambiri pakubadwa kwa mwana ndipo pambuyo pake. Ndi mkaka wa m`mawere, kuwunika tsiku ndi tsiku kumafunikira kwa miyezi ingapo (mpaka kufunika kwa insulin ndikukhazikika). Odwala omwe amalandira insulin yoposa 100 ya insulin patsiku amafuna kuchipatala posintha mankhwalawa.

Zotsatira zoyipa za insulin sungunuka waumunthu

Thupi lawo siligwirizana (angioedema, urticaria, kupuma movutikira, malungo, kutsitsa magazi),
hypoglycemia (kutuluka thukuta kwambiri, kufooka kwa khungu, thukuta, kunjenjemera, malovu, kugona, kuda nkhawa, kukhumudwa, kupweteka mkamwa, kugona, kupweteka mutu, kugona tulo, kukhumudwa, mantha, kusakwiya, kusayenda, kuchita zachilendo, kusokonekera kwa mawonekedwe mawu), hypoglycemic chikomokere, chikumbumtima chosavomerezeka (mpaka kukula kwa chikomokere ndi matenda okhudzana ndi matenda ashuga), matenda ashuga acidosis ndi hyperglycemia (amene ali ndi jakisoni, mankhwala ochepa, kudya pang'ono, matenda, oradicum): ludzu, kugona, Hyperemia ya nkhope, kuchepa kwa chakudya, kufupika kwakanthawi kowonekera (makamaka kumayambiriro kwa chithandizo), kuyabwa, hyperemia ndi lipodystrophy (hypertrophy kapena atrophy of subcutaneous adipose minofu) kumalo a jekeseni, kuchuluka kwa anti-insulin antibodies ndi kuwonjezereka kwa glyc immunological mtanda zimachitika ndi insulin ya anthu, kumayambiriro kwa chithandizo - kuphwanya Reflexion ndi edema (ndizakanthawi ndipo amachotsedwa ndi kupitiliza mankhwala).

Bongo

Ndi mankhwala osokoneza bongo, hypoglycemia imayamba (thukuta lozizira, kufooka, kufooka kwa khungu, kunjenjemera, malovu, mantha, kupweteka kwa miyendo, manja, lilime, milomo, njala, kupweteka mutu), kukokana, hypoglycemic chikomokere. Chithandizo: wodwalayo amatha kuthetsa vuto lokhala ndi matenda ofewa pogwiritsa ntchito chakudya kapena shuga. Glucagon imayang'aniridwa subcutaneous, intrausly, intramuscularly, kapena hypertonic dextrose solution imayendetsedwa pamitsempha, ndi hypoglycemic coma, 20-40 ml (mpaka 100 ml) ya 40% dextrose yothetsera jakisoni imalowetsedwa kudzera m'mitsempha mpaka wodwalayo atasiya kukomoka.

Kuchita ndi mankhwala ena

Zomwe zili patsamba lino zinatsimikiziridwa ndi katswiri wazachipatala Vasilieva E.I.

Momwe mungasankhire analog yoyenera
Mu pharmacology, mankhwala nthawi zambiri amagawidwa m'magulumagulu ndi ma analogi. Kapangidwe kazofananira kameneka kamaphatikizira amodzi kapena angapo amomwe omwewo omwe ali ndi mphamvu yothandizira thupi. Ndi ma analogi amatanthauza mankhwala okhala ndi zinthu zosiyanasiyana zogwira ntchito, koma zochizira matenda omwewo.

Kusiyana pakati pa matenda a ma virus ndi bakiteriya
Matenda opatsirana amayambitsidwa ndi ma virus, mabakiteriya, bowa ndi protozoa. Njira ya matenda oyambitsidwa ndi ma virus ndi ma bacteria nthawi zambiri imakhala yofanana. Komabe, kusiyanitsa chomwe chimayambitsa matendawa kumatanthauza kusankha njira yoyenera yomwe ingathandize kuthana ndi vuto losachedwa kudwala ndipo sizivulaza mwana.

Chifuwa ndi chomwe chimayambitsa chimfine pafupipafupi
Anthu ena amadziwa vuto lomwe mwana nthawi zambiri amakhala nalo kwa chimfine. Makolo amamutengera kwa madotolo, kukamuyeza mayeso, kugwiritsa ntchito mankhwala osokoneza bongo, ndipo monga chotulukapo chake, mwana amalembetsa kale ndi dotolo wa ana monga nthawi zambiri amadwala. Zoyambitsa zenizeni za kupuma pafupipafupi sizidziwika.

Urology: mankhwalawa a chlamydial urethritis
Chlamydial urethritis nthawi zambiri imapezeka pochita urologist. Amayamba chifukwa cha majeremusi a Chlamidia trachomatis, omwe ali ndi mphamvu ya mabakiteriya komanso mavairasi, omwe nthawi zambiri amafunikira njira yothandizira antibacterial. Imatha kuyambitsa kutupa kosakhudzana ndi urethra mwa amuna ndi akazi.

Soluble human genetic engineering insulin: malangizo ogwiritsira ntchito

Insulin engineering insulin idapangidwa kuti ikhale ndi insulin.

• Lembani I, lembani matenda ashuga II: mukakhala kotheka kuwongolera mankhwala a hypoglycemic kapena kusakhazikika kwawo
• Matenda a shuga ketoacidosis
• Coma
• Matenda a shuga pa nthawi yomwe ali ndi pakati (ngati chithandizo cha zakudya sichithandiza)
• Kugwiritsira ntchito kwakanthawi odwala matenda ashuga motsutsana ndi matenda opatsirana omwe ali ndi matendawa, pokonzekera opareshoni, kuvulala, kuvulala, matenda a metabolic, komanso kusinthana ndi ma insulin omwe amakhala nthawi yayitali.

Mankhwala a insulin aanthu ndi gawo la mankhwala ochokera kwaopanga osiyanasiyana, motero zida zothandizira ndizosiyana.

Mtengo: 10 amp. 1 ml iliyonse - kuchokera 177 ma rub., Makatiriji ma 5 ma PC. 3 ml -

1 ml ya jakisoni muli:

• Zogwira ntchito: 100 IU
• Zowonjezera: zinc chloride, glycerol, sodium hydroxide (kapena hydrochloric acid), madzi.

Mankhwala osokoneza bongo monga mawonekedwe amadzimadzi omveka bwino osagwiritsidwa ntchito ndi makolo. Atakulungidwa mu ma ampoules, ma syringe, mabotolo.

Wopangidwira pompopompo kuti mugwiritse ntchito matenda a shuga 1 kapena mtundu 2. Pambuyo kolowera, imakhudzana ndi ma receptor enieni pamimba ya cell, zomwe zimapangitsa kuti pakhale kupangika kwa insulin-receptor, komwe kumayambitsa kaphatikizidwe ka cAMP, kayendedwe ka mkati mwa cell, kuphatikizapo kapangidwe ka michere yofunika.

Kuchepa kwa glycemia kumachitika chifukwa cha kuchuluka kwa mayendedwe, kugwiritsa ntchito kwambiri, kuphatikiza mapuloteni othamanga, komanso kupanga shuga pang'onopang'ono ndi chiwindi.

Kukula kwa vuto la hypoglycemic pambuyo poti jekeseni akuwonekera pambuyo pa mphindi 15-30, kufikira pazofunikira pambuyo pa maola 1-3 ndikutsalira, kutengera kukula kwa mlingo womwe waperekedwa. Kutalika kwa chinthu chopangidwa ndi majini kumatsimikiziridwa ndi mlingo, malo ndi mtundu wa kayendetsedwe, komanso mawonekedwe a thupi la wodwalayo.

Thupi limabalalika mosiyanasiyana munsiyo, silidutsa pamkati ndi mkaka. Imaphwanya makamaka m'chiwindi, impso mothandizidwa ndi insulinase. Mitsuko imachotsedwa m'thupi.

Jekeseni wa chibadwa cha insulin yaumunthu amalumikizidwa pansi pa khungu kapena mu lumen ya mitsempha. Mlingo umasankhidwa payekha malinga ndi glycemic level. Kufunika kwa tsiku lililonse kwa mankhwalawa ndi 0.3-1 IU. Odwala omwe ali ndi insulin, amatha kukhala apamwamba, ndipo mwa anthu omwe ali ndi chinsinsi cha chinthucho, amatha kutsika.

Jakisoni amapangidwa theka la ola musanadye kapena kumwa zakudya zamatumbo. Kuti mupeze jakisoni wotsekemera, sankhani khomalo lakutsogolo la m'mimba, komanso kumtunda kwa ntchafu, matako kapena minofu yapamwamba kwambiri. Kwa milandu yachangu, pakakhala zofunika kusintha msanga glycemia, ndibwino kumeza m'mimba, chifukwa insulin pamenepa imalowetsedwa mwachangu.

Ngati mankhwalawa adayambitsidwa pakhungu, ndiye kuti chiwopsezo chofika minofu ndi chochepa. Pofuna kupewa kutuluka kwa mankhwalawa, ndikofunikira kuti musatulutse singano kwa masekondi 6 mpaka 10. Kuti mupeze jakisoni, muyenera kugwiritsa ntchito malo atsopano nthawi zonse kuti mupewe kuwonongeka kwa dermis ndi minofu yocheperako.

Kulowetsa mtsempha kumafunika chidziwitso chapadera komanso chidziwitso chochuluka, chifukwa chake, njirazi zimaloledwa kokha kwa akatswiri oyenerera azachipatala.

Musanayeze mulingo wa insulin yomwe unapangidwa kuchokera kumtundu kapena mkokomo, muyenera kuonetsetsa kuwonekera kwa yankho la jakisoni. Ngati pali chilichonse cholowa mkati mwake, choyimitsidwa kapena chidebe chokhala ndi mankhwalawo chikakanda, kuswedwa kapena kuyatsidwa, ndiye kuti mankhwalawo amawoneka kuti ndi osayenera kuyambitsa. Iyenera kutayidwa malinga ndi malamulo ovomerezeka.

Pamaso jakisoni, muyenera kutentha mankhwalawo mwanjira yachilengedwe kuti kutentha kwake kuli kofanana ndi kutentha kwa chipinda.

Mlingo wake ufunika kusinthidwa ngati wodwala ali ndi matenda opatsirana kapena matenda a chithokomiro. Kuwongolera kumafunikiranso pankhani ya matenda a Addison, ukalamba, kusowa kwa pituitary, kulephera kwa aimpso.

Hypoglycemia sayenera kuloledwa. Kukula kwake kumayendetsedwa ndi kuyambitsa insulin yochulukirapo, kusintha kosayenera kwa mankhwala, kudumpha chakudya, kusanza, kutsegula m'mimba, kuchuluka kwambiri, chiwindi ndi / kapena matenda a impso, kusowa kwa adrenal, kuphatikiza ndi mankhwala ena. Kuphatikiza apo, mulingo wa glycemia ukhoza kuchepa pambuyo posintha jekeseni, posamutsa kuchokera ku insulin ya nyama. Potsirizira pake, kusintha kwa zinthu zaumunthu kuyenera kuchitikira kuchipatala. Ndi zoletsedwa kubwezera mankhwalawo.

Isulin insulin

MALANGIZO: kukonzekera kwa maholide a pancreatic, ma insulin apakati, umisiri wamtundu wa anthu

Rp. Insulini isophani 5ml (100ME)

S:: 20 INI modekha kawiri pa tsiku.

MCHITO: amapanga insulin receptor zovuta pa nembanemba, imawonjezera cAMP, imalimbikitsa kaphatikizidwe ka michere (hexokinase, etc.). Kuchepa kwa kuchuluka kwa shuga m'magazi chifukwa chakuwonjezeka kwa mayendedwe ake amkati (mayamwidwe ndi zimakhala), kukondoweza kwa lipogenesis, glycogenogeneis, ndi kuchepa kwa kupanga kwa chiwindi ndi chiwindi (kuchepa kwa kuwonongeka kwa glycogen).

Dongosolo: T1DM, T2DM: siteji yotsutsana ndi matenda apakamwa, oyanjana, T2DM mwa amayi apakati.

MALANGIZO: HS, hypoglycemia.

KID:Zotsatira pakusinthana kwa U: hypoglycemia (pallor of the khungu, thukuta lochulukirapo, kugwedezeka, kugwedezeka, njala, kukwiya, paresthesia mkamwa, gb, hypoglycemic coma).Zotsatira zoyipa: zotupa pakhungu, edema ya Quincke. Zina: kutupa, zolakwika zosakhalitsa. Zomwe zimachitika: Hyperemia, kutupa ndi kuyabwa pamalowo jekeseni, ndikugwiritsa ntchito nthawi yayitali - lipodystrophy pamalo opangira jekeseni.

MALANGIZO: pakamwa antidiabetesic othandizira, minofu insulin kukana kuchepetsa othandizira, biguanides

Rp.: Tabl. Metformini 0,5

S: 1 piritsi 2 (kapena 1) kangapo patsiku (madzulo) mukatha kudya.

MCHITO: kumawonjezera chidwi cha insulin, kumapangitsa chidwi cha kugwidwa kwa glucose ndi minyewa yam'magazi, kumalimbitsa anaerobic glycolysis, kumachepetsa kutulutsa shuga m'matumbo ndi kupanga kwake mu chiwindi, kutsitsa glucagon m'magazi ndi LDL, cholesterol, ndi triglycerides, ndikuchepetsa chilimbikitso ndi kulemera kwa thupi.

Dongosolo: T2DM (makamaka kunenepa kwambiri) ndi kulephera kudya.

MALANGIZO: HF, aimpso / chiwindi / kupuma / mtima, kugunda kwa mtima, kuchepa magazi, kuchepa kwa magazi, matenda opatsirana, uchidakwa, metabolic acidosis, pakati, kuyamwa.

KID: GIT: pa chiyambi - matenda a anorexia, kutsekula m'mimba, kusanza, kusanza, kupweteka kwam'mimba, kulawa kwazitsulo mkamwa. CCC: megaloblastic anemia. Metabolism: hypoglycemia, kawirikawiri lactic acidosis (kufooka, kugona, hypotension, bradyarrhythmia, kupuma kwamatenda, kupweteka kwam'mimba, myalgia, hypothermia. Khungu: zotupa, khungu.