Glucophage 1000 mg: kuwunika kwa shuga ndi mtengo wamapiritsi

Matenda a shuga ndi matenda osachiritsika omwe amadziwika chifukwa chophwanya chithokomiro cha chithokomiro komanso zochita za metabolic m'thupi. Zotsatira zake, pali kuwonjezeka kwa shuga m'magazi. Matenda a shuga koyambirira amayendetsedwa ndi kadyedwe ndikuwonjezera zochitika zolimbitsa thupi, ndipo m'magawo owopsa a matendawa, mapiritsi ochepetsa shuga, monga Glucofage 1000 a shuga mellitus, amawonjezeredwa pamankhwala.

Zofunika! Ndi matenda a shuga, mankhwala, muyezo ndi nthawi ya chithandizo zimayikidwa ndi adokotala okha. Kudzichiritsa nokha kungavulaze thanzi komanso kuyambitsa zovuta zowopsa.

Glucophage - chisamaliro cha shuga

Musanapitirize chithandizo cha matenda aliwonse, ndikofunikira kuti muphunzire zonse zokhudza mankhwalawa kuti mupewe bongo, thupi lanu siligwirizana komanso osagwirizana ndi mankhwala ena.

Odwala masiku ano, matenda a shuga 2, kunenepa kwambiri, kuthamanga kwa magazi kumaonekera mwa anthu chifukwa cha metabolic syndrome. Monga lamulo, okhala m'maiko olemera akuvutika ndi izi, monga lamulo. Ndipo zifukwa zazikulu za mawonekedwe ake ndi izi: moyo wokakamiza, ntchito yokhalitsa, kukana masewera. Zotsatira zake, munthu amapeza mapaundi owonjezera ndi shuga wamagazi ambiri. Mankhwala Glucofage athandizira kukonza zinthu, amachepetsa shuga ndikuchepetsa kwambiri kunenepa.

Asayansi amati kumwa mankhwalawa kumachepetsa kufa kwa matenda otere:

• shuga - mwa 41%,
• myocardial infarction - 38%,
• stroke - mwa 40%.

Kapangidwe ka mankhwala ndi mawonekedwe a kumasulidwa

Glucophage imapezeka kokha mwa mapiritsi oyera, omwe cholinga chake ndi pakamwa. Mapiritsiwo ndi elliptical, convex kumbali zonse ziwiri. Maphokoso amakonzedwa mbali, ndikuwonetsa kuchuluka kwake. Mapiritsi amapezeka mu kipimo cha 500, 850 ndi 1000 mg. Mankhwala omwe akhala akuchita kwa nthawi yayitali amapezekanso - Glucofage Long, yokhala ndi Mlingo wa 500 ndi 750 mg.

Mapiritsi amayikidwa m'matumba a zidutswa 10, 15 kapena 20 chilichonse.

Chofunikira chachikulu cha glucophage kuchokera ku shuga ndi metformin. Mankhwalawa amakhalanso ndi povidone ndi magnesium stearate. Chipolopolocho chimakhala ndi macrogol ndi hypromellose.

Opanga mapiritsi ndi kampani yaku France ya mankhwala MerckSante.

Kodi mankhwalawa amakhudza bwanji thupi

Glucophage, yemwe ali mgulu la Biguanide, amapangidwa makamaka kuti achepetse shuga. Mankhwala amagwira ntchito mwanjira yoti achepetse shuga, munthu sathamanga kuti apeze vuto la hypoglycemia, ndipo mwa anthu omwe alibe shuga, kuchuluka kwa glucose kumakhalabe kwachilendo ndipo sikugwera pansi. Mphamvu ya mankhwalawa imachitika chifukwa chakuti glucophage mu shuga amawonjezera chidwi cha maselo kuti apange insulin. Zotsatira zake, shuga amapakidwa kwambiri, shuga siziwunjikana kwambiri m'chiwindi, ndipo mafuta ochulukirapo amaphatikizidwa bwino ndi ziwalo zam'mimba. Mankhwala amasintha pokonza mafuta, amachepetsa cholesterol, triglycerides ndi otsika kachulukidwe lipoproteins.

Glucophage ndiyabwino ndipo imatengedwa mwachangu ndi thupi kudzera m'makoma am'mimba, ndipo pafupifupi maola awiri atamwa, kuyang'anitsitsa kwake m'magazi kumawonedwa. Metformin imagawa mwachangu m'maselo onse amthupi ndipo sizikhudza kugwira ntchito kwa mapuloteni m'magazi. Mankhwalawa amachotsedwa mu mkodzo osakhudza chiwindi. Koma mwa anthu omwe ali ndi mavuto a impso, kuletsa kwa zinthu za Glucophage mu minofu ndikotheka.

Glucophage kunenepa kwambiri

Glucophage amaperekedwa kwa odwala onenepa.Kuchita kwa mankhwalawa kumadalira kuphatikiza oxidation wamafuta acids ndikuchepetsa kuyamwa kwa mafuta omwe amalowa mthupi ndi chakudya. Komanso, mothandizidwa ndi mapiritsi, maselo amathanso kukhala ndi insulin, yomwe imalepheretsa kuti chithokomiro chizitulutsa timadzi tambiri tambiri. Ndipo izi zimapangitsa kuchepetsa thupi, chifukwa amadziwika kuti insulin imasanduliza zakudya zomwe zimadyedwa ndi chakudya kukhala mafuta. Komanso, kuphatikiza kwa insulini m'thupi kumayambitsa kumva kukoma kwa njala, ndipo metformin imapangitsa kuti izikhala yochepa.

Mukamamwa Glucofage, madokotala amalimbikitsa zakudya zamafuta ochepa. Izi zimathandizira kuchepetsa kwambiri shuga ndi kuwonda.

Momwe mungatenge Glucophage kunenepa kwambiri:

• ngati cholinga chachikulu chamankhwala ndikuchotsa mapaundi owonjezera, ndiye kuti kuli bwino kumwa mapiritsi 3 katatu patsiku musanadye mu Mlingo wa 500 mg,
• kanani kapena muchepetse kugwiritsa ntchito zakudya zamafuta azakudya nthawi ya mankhwalawa (shuga, maswiti, makeke, mkate Woyera, zakudya zamafuta, ndi zina zambiri),
• kutsekula m'mimba pamene mukumwa mapiritsi kungasonyeze kuti kuchuluka kwa chakudya chamagulu ochulukirapo kumapezeka m'zakudya,
• ndi mseru, mulingo wa Glucofage ukhoza kuchepera,
• nthawi ndi nthawi kuti muthe kuchita bwino kwambiri pamafunika kuchita aerobics kapena maphunziro akuthupi,
• Njira yothetsera kunenepa kwambiri ndi Glucofage iyenera kukhala milungu itatu, ndiye kuti muyenera kupuma kwa miyezi iwiri yokhala ndi carb yotsika kenako kumwa mapiritsiwo kuyambiranso.

Momwe mungatenge Glucophage

Pambuyo pofufuza wodwalayo, motsogozedwa ndi zotsatira za mayeso, dokotalayo amapereka mankhwala omwe angathandize kwambiri. Kuchita nokha sikulimbikitsidwa.

Choyamba, adotolo amakupatsani mankhwala ochepetsa msambo (500 mg kapena 850 mg) katatu patsiku. Kenako, pakatha milungu ingapo, mlingo umachulukitsidwa kutengera momwe mankhwalawo amakhudzira wodwala. Malangizo a mankhwalawa amafotokozedwa chifukwa chakuti zomwe zimagwiritsidwa ntchito ndi mankhwalawa zimatha kusokoneza komanso zovuta zina m'matumbo am'mimba kumayambiriro kwa chithandizo. Nthawi zambiri, pakatha milungu iwiri, izi zimachitika. Kuti achepetse mkhalidwe wa wodwalayo panthawi ya kusintha kwa mapiritsi, adokotala amatha kuyambitsa ma antacid ndi antispasmodics. Popewa kupezeka kwa zoyipa, mankhwalawa amalimbikitsidwa kuti amwe ngakhale mukudya chakudya, kapena mutangomaliza kumene. Ngati vuto la m'mimba silili bwino, ndiye kuti mankhwalawo ayenera kuyimitsidwa.

1500-2000 mg - ndi mlingo wokonza. Mlingo wapamwamba tsiku lililonse ndi 3000 mg. Chifukwa chake, ngati mumwa mankhwalawa mu Mlingo waukulu, tikulimbikitsidwa kusinthira ku Glucofage 1000.

Ngati munthu watenga mankhwala ena ochepetsa shuga ndikuganiza zosinthira ku Glucofage, muyenera kaye kusiya kugwiritsa ntchito mapiritsi akale.

Ana amatha kumwa mankhwalawa kuchokera zaka 10 zakubadwa. Komanso, ana ndi achinyamata amathandizidwa ndi Glucofage limodzi ndi jakisoni wa insulin. Kumayambiriro kwa mankhwalawa, dokotala nthawi zambiri amapereka mankhwala osachepera 500-850 mg, ndiye, ngati kuli koyenera, mlingowo umakulitsidwa mpaka 2000 mg - iyi ndiye mlingo waukulu wa tsiku lililonse wa mankhwalawa. Ana ayenera kumwa Glucofage katatu patsiku.

Ponena za okalamba, ndikofunikira kuthandizidwa ndi mankhwalawa moyang'aniridwa ndi dokotala, chifukwa mankhwalawa angakhudze kugwira ntchito kwa impso.

M'pofunika kudziwitsa adokotala za kutha kwa mankhwalawa ndi glucophage

Odwala omwe amadalira insulin ayenera kuyamba kulandira chithandizo ndi Glucofage komanso osachepera Mlingo wa 500-850 mg. Kulandila kuyenera kugawidwa katatu. Kuchuluka kwa insulin pankhaniyi kuyenera kufanana ndi kuchuluka kwa shuga m'magazi.

Glucophage Kutalika. Mawonekedwe a phwando

Glucophage Long - mankhwala ochepetsa shuga a nthawi yayitali.

• Glucophage Kutalika 500 mg. Muyenera kumwa mankhwala ndi chakudya, makamaka madzulo.Mlingowo umaperekedwa ndi adokotala kutengera shuga la wodwala. Kumayambiriro kwa mankhwalawa, yambani ndi kuchuluka kwa mankhwalawa (500 mg patsiku). Pakatha masiku 14, kutengera zotsatira za mayeso, adotolo amatha kuwonjezera mlingo. Kufikira 2000 mg wa mankhwalawa amatha kumwa patsiku. Mumamwa mapiritsi, simuyenera kusintha mulingo wa insulin. Ngati wodwalayo adaphonya kumwa Glucofage, ndiye kuti ndizosatheka kuwonjezera kuchuluka kwa insulin.
• Glucophage Kutalika 750 mg. Muyenera kuyamba kumwa mapiritsiwo ndi mulingo wa 750 mg. Pambuyo masiku 14, adokotala amawunika ndi kusintha njira yochizira. Kudya komwe kumathandizira tsiku ndi tsiku ndi 1,500 mg, ndipo mlingo waukulu watsiku ndi tsiku ndi 2,250 mg.
• Ngati wodwala sangathe kusintha kuchuluka kwa shuga m'magazi mothandizidwa ndi mankhwala Glucofage Long, ndiye kuti asinthana ndi mankhwalawa Glucofage.
• Odwala omwe akutenga waukulu Mlingo wa Glucofage (oposa 2000 mg patsiku), osavomerezeka amasinthidwa kukhala mankhwala omwe amakhala nthawi yayitali.
• Mapiritsi amayenera kumezedwa lonse, simungathe kutafuna ndikuwapaka kukhala ufa.

Kodi ndingathe kumwa mankhwalawa amayi apakati kapena oyembekezera

Maganizo a asayansi pankhani yogwiritsa ntchito metformin ndi amayi apakati adagawidwa. Ofufuzawo ambiri amati ndiwosakanizidwa kuti azichizidwa ndi Glucophage panthawi yobala mwana, popeza mankhwalawa angakhudze kukula kwabwinobwino kwa mwana wosabadwayo. Ena amati kutenga metformin ndikotetezeka kwa thanzi la mayi ndi mwana wosabadwa.

Mulimonse momwe zingakhalire, ngakhale mayi atamwa mankhwalawa asanachitike, asanayambe mankhwala pa nthawi yomwe ali ndi pakati, ayenera kukambilana ndi dotolo ngati angathe kumwa Glucofage. Ndi dokotala yekhayo amene angasankhe ngati chithandizo ndi mankhwalawa ndi choyenera komanso ngati chitha kuvulaza mwana wosabadwayo.

Pa mkaka wa m`mawere, nkoletsedwa kumwa mankhwalawa, monga metformin ikudutsa mkaka wa m'mawere, ndipo palibe deta yokwanira pazomwe zimachitika chifukwa cha mankhwalawa kwa akhanda.

Katundu wa mankhwala

Matenda a shuga ndi matenda amtundu wa endocrine omwe amapangidwa motsogozedwa ndi zinthu zosiyanasiyana. Kuwonetsedwa kwakukulu kwa matendawa ndi kuchuluka kwa shuga m'magazi, mu mitundu ina ya matendawa - insulin chitetezo chokwanira cha maselo (insulin kukana) ndi kuchuluka kwa thupi chifukwa cha kuchuluka kwa chilakolako chofuna kudya. Glucofage 1000 mg imathandiza odwala kuthana ndi mawonetsedwe amtunduwu.

Zotsatira zotchuka kwambiri za mankhwalawa ndi hypoglycemic. Koma, mosiyana ndi mankhwala ena onse, izi sizimatheka chifukwa cholimbikitsa kupanga insulin mu kapamba. Pachifukwachi, kutenga Glucofage sikuyambitsa kuchuluka kwa shuga m'magazi (hypoglycemia), chifukwa chake sikuti kumayambitsa chifuwa cha hypoglycemic. Kuphatikiza apo, ngakhale anthu athanzi omwe amamwa mankhwalawa kuti awongolere kuchuluka kwa shuga kapena kuchepa thupi sangakhale ndi hypoglycemia.

Kutsitsa kwa shuga kumatheka chifukwa chogwiritsa ntchito zotumphukira zolandilira - amayamba kukonda insulin. Kuphatikiza apo, kugwiritsidwa ntchito kwa glucose ndi maselo kumakulitsidwa.

Kuphatikiza apo, mankhwalawa ali ndi katundu wina. Imachepetsa kuyamwa kwa glucose m'matumbo ndikulepheretsa mapangidwe a shuga m'chiwindi. Kuphatikiza pa hypoglycemic zotsatira, glucophage imasintha mafuta kagayidwe.

Gawo lalikulu la mankhwalawa, metformin, limalimbikitsa njira yopanga glycogen.

Kuphatikiza apo, mankhwalawa amathandizira odwala omwe ali ndi kunenepa kwambiri komanso onenepa kwambiri kuti achepetse kuchuluka kwa mafuta m'zinthu zopangidwira, zomwe zimathandizira mkhalidwe wa wodwalayo, zimayenda bwino. Kumwa mankhwalawa kumatha kuchepetsa kulakalaka, komwe kumathandizanso kuchepetsa kunenepa. Pazifukwa izi, nthawi zina, mapiritsi a glucophage amagwiritsidwanso ntchito ndi anthu athanzi ndi cholinga chochepetsa thupi.

Komabe, ochepa amawona kuchepa kwa chikondwerero, komanso mankhwalawa samakwaniritsa cholinga.

Mawonekedwe ndi mitundu yotulutsira mankhwala

Kuphatikizika kwa mankhwalawa kumaphatikiza mankhwala - metformin ndi zina zowonjezera.

Chodabwitsa cha mankhwalawa ndikuti pamene amamwa, gawo lofunikira la gawo lalikulu limaphatikizidwa. Kudya kumakupatsani mwayi kuti muchepetse njirayi, choncho muyenera kudya glucophage kokha ndi chakudya kapena mukangodya.

The bioavailability wa mankhwalawa ndi 50-60%. Chosakaniza chophatikizacho chimalowa mwachangu. Kuphatikiza kwa mapuloteni a plasma kumachitika, koma pang'ono. Zinthu zapamwamba kwambiri za m'magazi zimapezeka mu maola 2,5.

Metformin ndi yotsika kwambiri mu metabolism. Imafufutidwa msanga: theka la mankhwalawa limapukutidwa kudzera mu impso pambuyo pa maola 6.5.

Glucophage wa mankhwala amangogwira pakamwa.

Mapiritsi amasiyana amagwiritsidwa ntchito pophika:

Nthawi yomweyo, mapiritsi okhala ndi kuchepa kwa metformin (500 ndi 850 g) ndi ozungulira, a biconvex. Mapiritsi a 1000 mg ndi chowulungika, mbali imodzi pali zolemba "1000".

Glucophage imagulitsidwa m'mapaketi, omwe ali ndi maselo atatu. Selo iliyonse imakhala ndi miyala 20.

Zizindikiro ndi contraindication ntchito mankhwala

Chifukwa cha kutsika kwamphamvu kwa shuga, glucophage imayikidwa, choyambirira, kwa odwala matenda osagwirizana ndi insulin. Kwambiri, odwala matenda ashuga onenepa kwambiri omwe amafunikira chithandizo chamtundu wapamwamba, omwe sanathandizidwe ndi chithandizo chamankhwala komanso kuphunzitsidwa kuti achepetse thupi komanso shuga wambiri.

Glucophage imalengezedwanso kwa odwala omwe ali ndi prediabetes ngati pali zovuta zomwe zingachitike chifukwa cha kusintha kwa matenda ashuga kukhala mawonekedwe omveka.

Malangizowo akuwonetsa kuti mankhwalawa amatha kuthandizidwa ndi akulu ndi ana opitirira zaka 10. Nthawi yomweyo, kugwiritsa ntchito Glucophage monga mankhwala akuluakulu ndikuloledwa, komanso munthawi yomweyo ndimankhwala angapo, kuphatikizapo insulin. Kutenga Glucophage osakanikirana ndi insulin ndikulondola kwa odwala matenda ashuga.

Mankhwala ali ndi zotsutsana:

1. Matenda a shuga, kholo, ketoacidosis.
2. Kukhalapo kwa mawonekedwe a matenda mu pachimake kapena mawonekedwe osakhazikika, chifukwa mu nkhani iyi pamakhala chiopsezo cha minofu hypoxia.
3. Matenda a impso ndi chiwindi.
4. Posachedwa kuvulala kapena maopaleshoni ena, chithandizo chomwe chimaphatikizapo kugwiritsa ntchito insulin.
5. Lactic acidosis, kuphatikizapo mbiri ya.
6. Kusalolera payekha kwa metformin kapena zigawo zina za mankhwala.
7. Zakudya za Hypocaloric (tsiku lililonse kudya caloric zosakwana 1000 kcal).
8. Matenda opatsirana.
9. Hypoxia.
10. Mowa kapena uchidakwa.
11. X-ray wogwiritsa ntchito wothandizirana ndi ayodini.

Chowonongera cholakwika ndi zaka zamunthuyo - odwala omwe ali ndi zaka zopitilira 60 salimbikitsidwa kutenga Glucofage, chifukwa pamenepa mwayi wokhala ndi lactic acidosis ndiwokwera. Ndi chololedwa kugwiritsa ntchito mankhwalawa pokhapokha poonetsetsa momwe zinthu ziliri, makamaka kugwira ntchito kwa impso.

Kutenga Glucophage kumapangidwa pakati pa mimba ndi mkaka wa m`mawere. Ngati mimba yakonzekera kapena ikuchitika munthawi ya chithandizo, kugwiritsa ntchito mapiritsi kuyenera kuyimitsidwa. Kuphatikiza apo, ma analogu nawonso sangagwire ntchito - kumwa mankhwala m'malo mwake ndi jakisoni wa insulin. Zidziwitso zodalirika zakutha kwa zinthu za Glucophage kudutsa mkaka kulibe; panthawi yoyamwitsa, ndibwinanso kukana mankhwalawo. Ngati pakufunika kupitiliza chithandizo ndi glucophage, kuyamwitsa kuyenera kuyimitsidwa.

Malangizo owonjezereka mukamagwiritsa ntchito mankhwalawa

Lingaliro logwiritsira ntchito Glucofage pamankhwala limapangidwa ndi adokotala.

Asanaganize zogwiritsa ntchito mankhwala, dokotala amafunsira kuti apimidwe. Cholinga cha kuyesedwa kotero ndikukhazikitsa momwe thupi liliri.

Sankhani mlingo woyenera komanso kutsatira mosamala mukamalandira malangizo a Glucofage 1000, zotsatira zoyipa zimawonekera pang'onopang'ono, koma pali mwayi woti zimachitika.

Zina mwazotsatira zoyipa:

• Ziwengo - kuyabwa pakhungu, zotupa,
• mavuto ndi m'mimba thirakiti.
• kulawa kwazitsulo mkamwa
• kutsegula m'mimba
• kusanza
• nseru
• kupweteka kwam'mimba
• chisangalalo
• kusowa kwa chakudya.

Zovuta zam'mimba zimawonedwa kumayambiriro kwa kutenga glucophage. Nthawi zambiri pakapita kanthawi amadutsa popanda kuthandizidwa. Kuchepetsa kuopsa kwa zizindikiro zotereku kumatheka mwa kutenga antispasmodics kapena anthocin, komanso mwakutsata malamulo a kuvomerezedwa (pokhapokha kapena ndi chakudya).

Kuphwanya njira za metabolic - lactic acidosis - chikhalidwe chowopsa chomwe chikuwopseza imfa. Kukula kwa lactic acidosis kumayendera limodzi ndi zizindikiro za kugona (kugona, kuvuta kupuma, kusintha kwa mtima, kupweteka kwam'mimba), komanso kusowa kwa vitamini B12.

Ndi lactic acidosis, wodwala amafunikira kuthandizidwa kuchipatala mwachangu komanso mwaluso. Zotsatira zina zoyipa nthawi zambiri zimakhala zakanthawi, ndipo kugwiritsa ntchito mankhwalawa kwa nthawi yayitali kumakhala kokwanira. Komabe, ngati mawonekedwe osavutikawa ali ndi nkhawa kwambiri, ndizomveka kuyimitsa kugwiritsa ntchito Glucofage ndikuwonana ndi dokotala. Ithandizira kusintha regimen kapena kulangiza kufanana kwa mankhwalawo.

Mukamagwiritsa ntchito 85 g kapena kuposa mankhwala, bongo umachitika. Ngakhale ndi kuchuluka kumeneku, Glucofage siyipangitsa kuti shuga achepetse kwambiri, koma imayambitsa kukula kwa lactic acidosis. Vutoli limawonekera ndi zizindikiro monga kutentha thupi, kupweteka pamimba ndi minyewa, chizungulire, chikumbumtima, kupuma mwachangu, nseru, kutsegula m'mimba, kusanza, chikomokere. Ngati mukukayikira kuti mkaka acidosis, wodwalayo ayenera kuchipatala mofulumira. Chipatala chimazindikira kuchuluka kwa lactate, amapezeka.

Kuti muchotse lactate m'thupi, chithandizo chamankhwala ndi hemodialysis ndi mankhwala.

Malangizo ogwiritsira ntchito mankhwalawa

Musanagwiritse ntchito mankhwalawa, ndikofunikira kuphunzira malongosoledwe ndi malangizo atsatanetsatane kuti mugwiritse ntchito. Kutsatira malangizowa kumathandizira kupewa zoyipa ndi kulandira chithandizo mosakayikira.

Kwa wodwala aliyense, kuchuluka kwa mankhwalawa kuyenera kutsimikiziridwa payekhapayekha. Mlingo umatengera kuchuluka kwa shuga m'magazi. Kuchuluka kwa mankhwalawa ndi 500 mg, ndiye kuti, piritsi limodzi la Glucofage 500 kapena lu Glucofage 1000. Tengani Glucophage katatu patsiku. Popewa kuyamwa kwa chinthu chomwe chimagwira, mapiritsi amayenera kumwa ndi chakudya kapena mukangomaliza kudya, koma osati pamimba yopanda kanthu. Masabata 1-2 atayambika makonzedwe, mlingo umachulukidwa kutengera zotsatira za kuyeza kuchuluka kwa glucose komanso posakhala ndi zotsatira zoyipa. Kuwonjezeka kwapang'onopang'ono kwa mlingo kumachepetsa chiopsezo cha mavuto kuchokera m'mimba. Mlingo woyenera kwambiri ndi 3 g patsiku, wogawidwa pazigawo zitatu. Mlingo wokonza uyenera kutsikira - osapitirira 1.5-2 g patsiku.

Ndi mphamvu yochepa ya mankhwala a hypoglycemic, wodwalayo amatha kusamutsidwa kukalandira glucophage. Pankhaniyi, mankhwala oyamba ayenera kusiyidwa ndipo Glucophage amatengedwa ndi kuchuluka kololedwa.

Mu milandu yovuta ya matenda a shuga a 2, odwala amafunikira chithandizo chokwanira chomwe chimaphatikiza kuphatikiza mankhwala ochepetsa shuga komanso kuyang'anira insulin. Ndemanga zomwe zimasiyidwa ndi odwala zikusonyeza kuti Glucofage nthawi zambiri imalimbikitsidwa pazinthu zotere kuti muchepetse shuga. Mlingo woyambirira mwachangu ndi 500-850 mg 2-3 kawiri pa tsiku. Kuchuluka kwa insulin kumasankhidwa kwa wodwala aliyense payokhapokha, kutengera kuchuluka kwa shuga.

Kwa odwala omwe ali ndi zaka zopitilira 60, mlingo waukulu ndi 1000 mg patsiku.Pa chithandizo, mayeso pafupipafupi amafunikira kuyendetsa magwiridwe antchito a impso.

Zochizira matenda amtundu wa shuga wachiwiri kwa ana, mankhwalawa amagwiritsidwa ntchito ngati mankhwala onse, komanso kuphatikiza insulin. Muyenera kuyamba kulandira mankhwalawa osachepera 500 mg, kenako ndikuwonjezera pang'onopang'ono mpaka 2000 mg patsiku. Kuchuluka kwa mankhwalawa kumagawidwa pawiri.

Mapiritsi a Glucophage ayenera kumwedwa kokha, osafuna kutafuna. Mutha kumwa ndi kuchuluka kwa madzi.

Mtengo ndi fanizo la mankhwala

Mutha kugula mankhwalawa Glucofage mumasitolo wamba amzindawo, koma sagwiritsidwa ntchito ndi mankhwala pamsika waulere. Kuti mupeze mankhwalawa, muyenera kukhala ndi mankhwala kuchokera kwa dokotala.

Mtengo wogulitsa wa mankhwalawa umasiyanasiyana kutengera dera lomwe wagulitsidwa komanso mtundu wa mankhwalawo amasulidwe. Mapiritsi a Glucofage 500 adzawononga ndalama zochepa, mtengo wawo umakhala pakati pa ma ruble 120 (mapiritsi 30 pachikwama chilichonse) ndi ma ruble 170 (mapiritsi 60). Mtengo wa Glucofage 1000 umasiyana ndi ma ruble 190-200 (mapiritsi 30) ndi ma ruble 300 (mapiritsi 60).

Ngati Glucophage kulibe mankhwala ogulitsa mzindawo, kapena zimayambitsa zovuta zina, dokotala yemwe amapezekapo akhoza kumwa mankhwala osokoneza bongo. Mankhwalawa akuphatikizapo:

Muyenera kusungitsa mankhwalawo pamalo odera obiriwira - kutentha kwake osayenera kupitirira 25 digiri. Malowa sayenera kupezeka kwa ana. Kutalika kwakusungidwa ndi zaka zitatu za mapiritsi a Glucofage 1000 ndi zaka 5 kwa Glucofage 500 ndi 850. Pambuyo pa kumaliza kwake ntchito, ndizoletsedwa kumwa mankhwalawa. Moyo wa alumali umasonyezedwa phukusi.

About hypoglycemic mankhwala Glucophage akufotokozedwa mu kanema munkhaniyi.

Contraindication ndi zoyipa

Kumwa mankhwalawo ndizoletsedwa ngati wodwala ali ndi matenda kapena mavuto:

• Kuwonongeka kwa impso, kulephera kwaimpso. Amaletsedwanso kutenga metformin ngati wodwala ali ndi matenda amtunduwu komanso kuchepa kwa madzi m'thupi chifukwa cha m'mimba kapena kusanza.
• Matenda omwe amayambitsa kuperewera kwa mpweya m'matupi - kulowetsedwa kwak pachimake, kuperewera kwa mtima.
• Zowonongeka ndi ntchito.
• Matenda a chiwindi.
• Matenda a shuga a ketoacidosis, chikomokere kapena matenda ena.
• Kuledzera ndikuledzera.
• Lactic acidosis.
• Thupi lawo siligwirizana ndi zinthu mankhwala.
• Ndi zoletsedwa kumwa mankhwala aanthu pazakudya zochepa zama calories (mpaka 1000 kcal).
• Asanapimidwe X-ray, ngati pakufunika kumwa mankhwala okhala ndi ayodini, ndizoletsedwa kumwa Glucofage mkati mwa maola 48 isanachitike komanso pambuyo pa njirayi.

Wodwala yemwe akutenga Glucofage amatha kumva mseru, kupweteka m'mimba ndi matumbo, kusintha kwa kakomedwe, kusowa kwa chakudya, ndi kutsekula m'mimba kumatha kuchitika koyambirira kwamankhwala. Izi zimachitika kawirikawiri ndipo nthawi zambiri zimatha patatha masiku 10-14.

Pafupipafupi, mutatha kutenga metformin, zimachitika zovuta kwambiri kumachitika, zimaphatikizapo:

• kukula kwa chiwindi ndi chiwindi kukomoka,
• mawonekedwe a erythema,
• kusowa kwa vitamini B12,
• lactic acidosis yamtundu 2 shuga,
• zotupa pakhungu ndi kuyabwa.

Mankhwalawa samayambitsa kutsika msanga komanso kwamphamvu kwa shuga, komanso samayambitsa chizungulire komanso kuchepa kwa chidwi, chifukwa chake, kuyang'anira kwa zida zamagetsi ndi magalimoto sikuletsedwa pomwe mukumwa mapiritsi.

Wodwala ayenera kukumbukira kuti munthawi yomweyo Glucofage ndi mankhwala ena ochepetsa shuga, kuphatikiza jakisoni wa insulin, zitha kuyambitsa kukula kwa hypoglycemia

Mitengo ya Glucophage m'masitolo ogulitsa mankhwala ku Moscow

Madokotala amawunika za glucophage

Amachepetsa shuga m'magazi popanda kuchititsa hypoglycemia, kumenyana ndi insulin, kumakhudza metabolidi ya lipid, amachepetsa kuyamwa kwa m'matumbo ndikuthandizira kuchepetsa thupi, zomwe ndizofunikira kwambiri kwa odwala omwe ali ndi metabolic syndrome komanso kunenepa kwambiri.

Odwala amafotokoza zovuta za mseru, matenda am'mimba. Potengera maziko a kumwa mankhwalawa, chiwindi ndi impso zimafunikira.

Mulingo wa golide pochiza osati mtundu wachiwiri wa shuga, komanso prediabetes. Ndi kugwiritsa ntchito pafupipafupi kwa odwala, osati kuchuluka kwa shuga wamagazi kokha komwe kumachepetsedwa, komanso kulemera kwa thupi. Kuopsa kwa hypoglycemia kumakhala kotsika.

Nthawi zonse muziwerengera GFR musanapereke mankhwala. Ndi gawo 4 CKD, mankhwalawa sawonetsedwa.

Mankhwala enieni ndi othandizadi ndipo amakhala ndi zotsika zina zoyipa akapatsidwa mankhwala moyenera. Mitundu yambiri ya ntchito ndi yotakata, kuyambira kulemera kambiri, mtundu wachiwiri wa matenda ashuga, kutsutsana ndi insulin m'matenda ena, kumatha pokonzekera ma ART, odwala PCOS, muzochita za ana, komanso mankhwala othandizira odwala zaka. Amasankhidwa pokhapokha atakakumana ndi katswiri. Mtengo wololera.

Mankhwala abwino kwambiri. Ndimagwiritsa ntchito, moyenera, m'njira zina zochepetsera kubereka kwa amuna omwe ali ndi hyperglycemia komanso kunenepa kwambiri. Ubwino wake ndi kuti ukagwiritsidwa ntchito, sayambitsa hypoglycemia.

Zosagwirizana ndi mowa, zomwe zimakhala ndi ayodini. Chenjezo liyenera kugwiritsidwa ntchito ngati vuto laimpso likuwonekera.

Itha kufotokozedwa mu zovuta zovuta zothandizira kubereka kwa abambo ndi andrologist monga momwe amagwirizana ndi endocrinologist.

Ndimagwiritsa ntchito mankhwalawa mankhwalawa matenda a matenda ashuga a 2, onenepa kwambiri. Thandizani kuchepa thupi popanda kuwononga thanzi lanu, kuletsa kukalamba kwa thupi. Mphamvu yaukatswiri yamankhwala imatsimikiziridwa. Mtengo wotsika mtengo wa mankhwalawo.

Mankhwala ogwira ndi kutsimikiziridwa.

Mankhwala oyamba kwambiri pamtengo wotsika mtengo. Amakonda kuchepa thupi.

Matenda am'mimba.

Mankhwala osokoneza bongo. Mankhwala okhala ndi mbiri yayitali, ogulitsidwa m'maiko ambiri padziko lapansi. Pochita zachipatala, ndimagwiritsa ntchito mankhwalawa. Ntchito mankhwalawa onenepa kwambiri.

Nkhondo yolimbana ndi insulin, kusowa kwa hypoglycemia, mwayi wogwiritsa ntchito osati matenda ashuga okha. Sizimayambitsa kufooka kwa cell ya beta.

Odwala ena amati amamwa m'mimba akamamwa mankhwalawa.

Mankhwala apadera okhala ndi mbiri yayitali, zotsatira zabwino osati kokha pakuchepetsa shuga, komanso kulemera.

Muzochita zanga zamankhwala, ndimapereka mankhwala a Glucophage kwa odwala omwe ali ndi matenda osokoneza bongo, kuphatikizapo odwala omwe ali ndi kunenepa kwambiri. Amachepetsa kuchuluka kwa shuga wopangidwa ndi chiwindi, komanso amachepetsa kuyamwa ndi matumbo. Kuchulukitsa kagayidwe kachakudya kwa odwala, kumathandizira kuchepetsa kunenepa kwambiri. Zotsatira zoyipa ndizogwiritsidwa ntchito moyenera sizigwirizana.

Mankhwala oyamba kwambiri pamtengo wotsika mtengo. Amakonda kuchepa thupi.

Matenda am'mimba.

Mankhwala othandiza kwambiri, muyezo wa "golide" wa matenda a shuga a 2. Sichimayambitsa hypoglycemia. Kuphatikizidwa ndi chithandizo cha kunenepa kwambiri. Kuvomerezedwa kuti mugwiritse ntchito muubwana.

Kugwiritsa ntchito osati kwa matenda ashuga okha.

Zosagwirizana ndi mowa.Kudya zakudya zopatsa mphamvu kumapangitsa kuti pakhale chopondapo.

Mankhwala apadera amtsogolo. Kafukufuku wamakono awonetsa kuthekera kwakukulu kwa mankhwalawa kutalikitsa moyo wa munthu. Amachepetsa mwayi wokhala ndi matenda ambiri a oncological ndipo amagwiritsidwa ntchito pochotsa kunenepa kwambiri.

Maganizo a odwala a Glucophage

Ndinayamba kutenga Glucophage ndipo ndinamva bwino. Amachepetsa shuga ndipo kunenepa kwambiri kumandisiya pang'onopang'ono. Ingotengani muyenera kuwonjezera pang'onopang'ono mlingo. Poyamba, ndidatenga 250 mg kwa masiku 10, kenako ndikusinthidwa kukhala 500 mg, ndipo tsopano ndimatenga 1000 mg.

Chimodzi mwa mankhwala abwino kwambiri kwa ine pa metformin. Ndimakonda zotsika mtengo, zoyenera komanso zoyambirira. Atatengedwa, adachepetsa shuga. Panalibe zotsatirapo zoyipa, monga zimakhalira ndi ma genetic. Ndipo mtengo wake ndi wokwanira.

Ndimamwa Glucophage nditapezeka ndi mtundu wachiwiri wa matenda a shuga. Nditamwa mankhwala ena omwe amachokera pa metformin, panali kudzimbidwa, koma Glucofage sizinadzetse zotsatirapo zilizonse, motero ndidaganiza kuti ndizimwa pambuyo pake. Miyezi isanu ndi umodzi yadutsa - mayeso ndi abwinobwino, ndikumva bwino. Ndipo adatha kuchepetsa thupi moyenera panthawiyi: pafupifupi 15 kg. The endocrinologist adaonjezera maphunziro anga kwa miyezi ina iwiri. Panthawi imeneyi, ndidzataya kilogalamu yowonjezera yomaliza.

Pomwe, malinga ndi zotsatira za mayeso, adapeza kuchuluka kwa shuga m'magazi, adawopa kwambiri shuga. The endocrinologist adalamula kudya kwapadera ndi kusamala kwambiri shuga, kuphatikizapo Glucofage. Mlingo anali osachepera 500 mg. 2 kawiri pa tsiku, mwezi umodzi pambuyo pake idakwera mpaka 1000x2. Kwa miyezi itatu, shuga adatsikira kumalire otsika ndipo pamakala anali opanda 7 kg). Ndikumva bwino tsopano.

Tsiku labwino kwa onse owerenga ndemanga zanga! Ndi mankhwala "Glucophage" akudziwika posachedwa. Poyamba sindinkakhala ndi mavuto azaumoyo, koma posachedwa, katswiri wa endocrinologist wandipatsa shuga ndikuwuza Glucophage kuti achepetse shuga. Mayi anga ankadwala matenda ashuga moyo wawo wonse, motero kudziwa kumeneku sikunadabwe kwambiri. Matenda a shuga si shuga pano, koma pali zofunika kale, ndipo ngati simukugwirizana ndi thanzi lanu, ndiye kuti matenda a shuga sakhala patali. Ndinayamba kumwa piritsi limodzi la "Glucophage" 1 madzulo. Poyamba, ndinkaopa kuti mavuto aliwonse amtundu wa m'mimba angayambike, koma sizinachitike ngati izi. Glucophage adandilandira bwino komanso adandichitira zabwino. Kugona komanso kumangokhala wotopa kumatha, mphamvu zambiri zinayamba, ndipo ngakhale kusinthasintha kunasiya kudumpha, ngati kale. Pang'onopang'ono, kuchuluka kwa "Glucophage" ndi dokotala kunakulitsidwa. Kuyambira 500 mg, tinasinthira ku 1000 mg. Kenako mumayenera kumwa 2000 mg patsiku. Kuchulukitsa mlingo wa Glucofage sizinawononge thanzi langa. Dotolo adandiuza kuti ndilandire miyezi itatu. Tsopano ndikupitiliza kutenga Glucophage. Mapiritsiwo ndi akulu mokwanira ndipo nthawi zina zimakhala zovuta kumeza. Ayeneranso kutsukidwa ndi madzi ambiri. Koma chofunikira kwambiri ndikuti amenya shuga bwino. Ndipo pali chinthu chimodzi chofunikira cha Glucophage, makamaka kwa anthu onenepa kwambiri. Mankhwala othandizira a Glucophage, metformin, amathandizira kuchepetsa thupi. Ndimamva momwe zimandikhudzira. Panthawi yomwe ndimatenga Glucophage, ndidataya makilogalamu 12. Tsopano ndili bwino kwambiri ndipo sindimvekanso ngati mayi wamkulu wopanda mawonekedwe)) Kulemeraku sikunawonekere kwa ine, ndipo tsopano ndinasinthiratu zovala zanga. Tsopano kulemera kwayima, mwachionekere, zonse zomwe ndimafuna, ndidataya kale. Metformin imalepheretsa kupezeka kwa chakudya chamthupi ndipo imasintha kagayidwe m'thupi. Chifukwa cha katunduyu, mapaundi onse owonjezera amapita. Koma sindingalangize kutenga Glucophage kwa anthu onenepa kwambiri popanda kuyang'aniridwa ndi dokotala. Ndikuganiza kuti mankhwala aliwonse amafunika kuyang'anira akatswiri.

Amakakamizidwa kumwa mankhwalawa pa metformin chifukwa cha matenda a shuga a 2.Koma mankhwalawa ndiabwino: akagwiritsidwa ntchito moyenera, samapangitsa kuti pakhale zovuta, amalimbana bwino ndi ntchito yake yayikulu - kutsitsa shuga wamagazi, ndikuthandizira kutaya zochuluka zonse poyamba. Ndimatenga tsiku lililonse mlingo wa 850 mg.

Ndili ndi matenda a shuga a 2 omwe amandidalira, ndimakhala ndikumamwa Glucophage chaka chachisanu ndi chinayi kale. Poyamba ndidatenga Glucofage 500, mapiritsiwo adathandiza kwambiri, tsopano ndimatenga 1000 m'mawa ndi 2000 usiku. Glucose m'magazi idakalipobe kwambiri, koma ndikufuna kudziwa kuti kumwa insulin popanda mapiritsi sikutulutsa kanthu kofanana ndi Glucofage. Ndikuganiza kuti amandithandiza kwambiri. Koma kuchepa thupi kwa zaka zisanu ndi zinayi sikunawonedwe konse. Amapereka mankhwala ena kwaulere, koma ndimapiritsi a Glucofage omwe ndimamvanso bwino. Ndikudziwa kuti anthu ambiri amamwa mapiritsi awa, koma sagwira ntchito kwa ine, ndipo panalibe chowongolera. Zotsatira zoyipa sizinawonedwe. Wolekeredwa bwino.

Ndinayamba kumwa mankhwalawa mosamala, pa 250 mg. Pambuyo mwezi woyamba wa makonzedwe, shuga anali atayandikira pafupifupi (7-8 mayunitsi), ndipo kulemera kwake sikuima. Iyenso adadabwa ataona mamilimita atatu osapindulitsa pamiyezo ndipo ili ndi mwezi wokha.

Glucophage adandiuza ine endocrinologist wa kuwonda. Mlingo 850 mg, kawiri tsiku lililonse, piritsi limodzi. Amandidwalitsa. Ndinkadwalitsa chizungulire, ndinali ndimatumbo otayirira, ndipo nthawi zambiri ndimathamangira kuchimbudzi. Chifukwa chake, ndinayenera kusiya kumwa mapilitsiwa, patatha miyezi isanu ndi umodzi ndinasankha kuyesanso kumwa, koma tsoka, zotsatirazi ndizofanana, nseru kwambiri.

Adatenga "Glucophage 1000". Mimba yanga idayamba kupweteka kwambiri, ndipo sizinapite milungu iwiri. Adotolo adatanthauzira Glucophage Long - zonse zili m'dongosolo. Zowona, sindikutsimikiza kuti ndimafunikira mankhwalawa, ndilibe matenda ashuga, koma ndidapereka mankhwala a endocrinologist, ndiye ndimamwa. Kuthetsa matenda a insulin.

Type 2 shuga. Ndikuvomereza Glucophage Long. Imalekeredwa bwino. Ndimakonda kuti mungatenge kamodzi kokha patsiku.

Ndimamwa glucophage kwa zaka zitatu, 500 mg 2 kawiri pa tsiku. Kulemera kumachuluka tsiku lililonse. Musakonde mankhwalawo.

Mayi anga ali ndi matenda osokoneza bongo a digiri yachiwiri. Adalemba metformin, inde, amapatsa maulere zamagetsi, zotsika mtengo, zopanda ntchito. Koma tidaganiza kuti timugulira glucophage. Glucophage ndi mankhwala oyamba, makamaka France. Mtundu wabwino kwambiri komanso mtengo wokwanira. Adayesa mankhwala ena - otsika mtengo komanso okwera mtengo, koma amakhazikika pamenepo.

Pa mlingo wapamwamba 500, mutu wanga unayamba chizungulire. Ndinayeneranso kutsanso mlingo. Ngakhale kulolerana kuli bwino kuposa siofora.

Ndili ndi matenda ashuga 2: Ndili pachakudya, ndimachita masewera, ndikudzigaya ndekha ndi madzi ozizira. Glucose sapitirira 7, ndikulakalaka aliyense akhale ndi mwayi wokhala opanda mapiritsi.

Apongozi anga ali ndi matenda a shuga, amatenga Glucofage. Kalanga ine! M'mafakitala ambiri, ma dummies amagwiritsidwa ntchito m'malo mwa mankhwala. Mnzake wochokera ku Germany adabwera kwa apongozi anga (nawonso amatenga mankhwalawa), adagula mu mankhwala athu ndipo patsiku lachiwiri shuga wake udayambanso. Ndinatenga mapiritsi otsalawo kunyumba nane, ndinawupima kuti aunike, voila - mavitamini. Chifukwa chake, ndibwino kuti mugule mumasitolo odalirika kapena m'malo osungiramo katundu. Pali makampani ambiri ogulitsa ndi fake.

Pambuyo pobadwa kwa mwana, adanenepa kwambiri. Zomwe sindinayese - zakudya zosiyanasiyana, tiyi ndi glucophage kuphatikiza. Malinga ndi zomwe ndapeza, ndimachepetsa thupi, koma osati zambiri. Thirani makilogalamu 7 m'miyezi iwiri. Zowona, khungu pamimba yanga yolimba ndikuwongola matumbo lidapita. Lamulo lofunika kwambiri ndikuwonetsetsa kuti muzidya zakudya zoyenera ndi zakudya. Kutsekemera ndi mafuta kunatheratu. Zakudya zake zinali zomanga thupi. Amayi anali atachita masewera olimbitsa thupi kunyumba, adathamanga m'mawa, mwamuna wake adayamba kudandaula kuti akudzuka, koma ine kulibe. Ndiye, mwachidziwikire, ndidakondwera kwambiri ndi zotsatira kuposa ine. Glucophage inandithandiza kuchepa thupi, chamoyo chilichonse chimakhala payekha ndipo zochita zake zimakhala zosiyanasiyana.Onetsetsani kuti mwayang'ana dokotala musanagwiritse ntchito, monga momwe ndidachitira.

Mayi anga akhala ndi matenda a shuga kwa zaka zambiri. Anayamba kugwiritsa ntchito insulin zaka zisanu zapitazo. Ndipo chaka chatha, adokotala adamuwuza Glucophage. Chifukwa chake ndi cholesterol yowonjezera komanso zovuta zama metabolic. Amayi anali bwino ndipo anali ndi vuto loti anali kupuma - sanadzuke mpaka pachipansi chachiwiri. Pambuyo pa miyezi isanu ndi umodzi ya kumwa glucophage, kuyesedwa kwa cholesterol, khungu la chidendene linasiya kuphulika ndipo mkhalidwe wamba unasintha. Amayi akupitilizabe kumwa mankhwalawa, koma amawunikira zakudya - izi ndizofunikira kuti ayike glucophage.

Kufotokozera kwapfupi

Masiku ano, ma endocrinologists ali ndi mitundu yambiri ya mankhwala omwe amachepetsa shuga omwe ali ndi umboni wokwanira wotetezeka komanso kuchita bwino kwawo. Ndizodziwika kale kuti mchaka choyamba chogwiritsira ntchito mankhwalawa pochiza matenda a shuga, kugwiritsa ntchito bwino kwamagulu osiyanasiyana a othandizira a hypoglycemic (biguanides, sulfonylamides), ngati akusiyana, sikofunika. Pankhani imeneyi, popanga mankhwala, munthu akuyenera kuwongoleredwa ndi zina zomwe zimagwiritsidwa ntchito ndi mankhwalawa, monga: momwe mtima ndi mitsempha yamagazi imalumikizana ndi kudya kwawo kwa zovuta zazikulu zam'magazi, chiopsezo cha kuyambuka ndi kuchuluka kwa atherogenic pathologies. Inde, ndi “nthomba” yoyambira yokha imeneyi yomwe imafunsa mwachangu funso loti "kodi pali moyo pambuyo pa matenda ashuga?" Kuyang'anira kwa nthawi yayitali kuchuluka kwa shuga m'magazi kumakhala kovuta kwambiri chifukwa cha kuwonongeka kwamphamvu kwa ntchito ya β-cell. Pachifukwa ichi, kufunikira kwa mankhwala oteteza maselo, mphamvu zawo ndi ntchito zake zikukula. Mwa mulu wazidziwitso zamayendedwe azachipatala ndi miyezo yothandizira matenda ashuga omwe adatengedwa m'maiko osiyanasiyana, mzere wofiira ndi dzina lomwelo: glucophage (INN - metformin). Chithandizo cha hypoglycemic ichi chakhala chikugwiritsidwa ntchito polimbana ndi matenda a shuga 2 kwazaka zoposa makumi anayi. Glucophage, ndiye, mankhwala okhawo odana ndi shuga omwe amathandizira kuchepetsa zovuta za matenda ashuga. Izi zidawonetsedwa bwino mu kafukufuku wamkulu yemwe adachitika ku Canada, pomwe odwala omwe amatenga glucophage anali ndi ziwengo zonse za 40% zamitima yakufa poyerekeza ndi omwe amamwa sulfonylureas.

Mosiyana ndi glibenclamide, glucophage simalimbikitsa kupanga kwa insulin komanso sikuti imapangitsa kuti zochita za hypoglycemic zisinthe. Makina akulu a zochita zake amakhala ndi cholinga chowonjezera mphamvu ya zotumphukira minofu yolandirira (makamaka minofu ndi chiwindi) ku insulin. Poyerekeza zakumbuyo ya insulin, glucophage imakulanso kugwiritsidwa ntchito kwa glucose pogwiritsa ntchito minofu ndi matumbo. Mankhwala amapititsa patsogolo kukhathamiritsa kwa glucose popanda mpweya ndipo amathandizira kupanga glycogen mu minofu. Kugwiritsa ntchito glucophage kwanthawi yayitali kumakhudzanso kagayidwe ka mafuta, komwe kumayambitsa kuchepa kwa kuchuluka kwa cholesterol (LDL) yathunthu m'magazi.

Glucophage imapezeka m'mapiritsi. Nthawi zambiri, kudya kumayamba ndi kumwa kwa 500 kapena 850 mg katatu patsiku pakudya kapena mutatha kudya. Nthawi yomweyo kuyang'anitsitsa shuga m'magazi kumachitika, malinga ndi zotsatira za kuchuluka kwakukulu kwa mlingo mpaka 3000 mg patsiku ndikotheka. Mukamamwa glucophage, odwala omwe amakhala ndi "zakudya" zawo zam'magazi amayenera kugawa chakudya chilichonse chomwe chimaperekedwa patsiku. Ndi kunenepa kwambiri, zakudya zama hypocaloric zimasonyezedwa. Glucofage monotherapy, monga lamulo, sagwirizana ndi hypoglycemia, komabe, mukamamwa mankhwalawo ndi othandizira ena a antihyperglycemic kapena insulin, muyenera kukhala osamala ndikuwonetsetsa magawo anu a biochemical.

Pharmacology

Oral hypoglycemic mankhwala ochokera pagulu la Biguanide.

Glucophage ® imachepetsa hyperglycemia, popanda kutsogola kukula kwa hypoglycemia. Mosiyana ndi zotumphukira za sulfonylurea, sizimalimbikitsa kutulutsa insulin ndipo sizikhala ndi vuto loti munthu azikhala wathanzi.

Zimawonjezera chidwi cha zotumphukira zolandilira ku insulin ndikugwiritsa ntchito shuga ndi maselo. Imachepetsa kupanga shuga kwa chiwindi poletsa gluconeogeneis ndi glycogenolysis. Kuchepetsa mayamwidwe m'matumbo.

Metformin imalimbikitsa kapangidwe ka glycogen pochita glycogen synthetase. Kuchulukitsa kuchuluka kwa mayendedwe amtundu uliwonse wa ma membrane glucose.

Kuphatikiza apo, ili ndi phindu pa metabolidi ya lipid: imatsitsa cholesterol yathunthu, LDL ndi TG.

Ngakhale mutamwa metformin, thupi la wodwalayo limakhalabe lolimba kapena limatsika pang'ono.

Pharmacokinetics

Mutatha kumwa mankhwalawo mkati, metformin imatenga gawo lonse la chakudya. Ndi kuyamwa kwa munthawi yomweyo, kuyamwa kwa metformin kumachepetsedwa ndikuchedwa. Mtheradi bioavailability ndi 50-60%. C_max mu plasma pafupifupi 2 μg / ml kapena 15 μmol ndipo zimatheka pambuyo maola 2,5.

Metformin imagawidwa mwachangu mu minofu ya thupi. Sizikugwirizana ndi mapuloteni a plasma.

Amachepetsa pang'ono ndi kupukusidwa ndi impso.

Kuvomerezeka kwa metformin mwa anthu athanzi ndi 400 ml / min (kanthawi kuposa KK), komwe kumawonetsa katulutsidwe ka tubular.

T_1/2 pafupifupi maola 6.5

Pharmacokinetics mu milandu yapadera yamankhwala

Odwala ndi aimpso kulephera T_1/2 ukuwonjezeka, pamakhala chiwopsezo cha kukopeka kwa metformin mthupi.

Kutulutsa Fomu

Mapiritsi, oyera-okutira oyera, ozungulira, biconvex, pamtanda - gulu loyera loyera.

Omwe amathandizira: povidone - 20 mg, magnesium stearate - 5.0 mg.

Zomwe zimapangidwa ndi nembanemba wa filimu: hypromellose - 4.0 mg.

Ma PC 10 - matuza (3) - mapaketi a makatoni.
Ma PC 10 - matuza (5) - mapaketi a makatoni.
15 ma PC. - matuza (2) - mapaketi a makatoni.
15 ma PC. - matuza (4) - mapaketi a makatoni.
20 ma PC. - matuza (3) - mapaketi a makatoni.
20 ma PC. - matuza (5) - mapaketi a makatoni.

Mankhwala amatengedwa pakamwa.

Monotherapy ndi kuphatikiza mankhwalawa ndi ena othandizira pakamwa

Mulingo woyambira woyamba ndi 500 mg kapena 850 mg 2-3 nthawi / tsiku mutadya kapena pakudya. Kuwonjezereka kwapang'onopang'ono kwa mlingo kumatha kutengera kuchuluka kwa shuga m'magazi.

Mankhwala okonza mankhwalawa nthawi zambiri amakhala 1500-2000 mg / tsiku. Kuti muchepetse mavuto kuchokera m'matumbo am'mimba, mlingo wa tsiku ndi tsiku uyenera kugawidwa mu Mlingo wa 2-3. Mlingo wapamwamba kwambiri ndi 3000 mg / tsiku, wogawidwa mu 3 waukulu.

Kuchepetsa pang'ono kwa mankhwalawa kungathandize kusintha kulolerana kwa m'mimba.

Odwala omwe amalandila metformin mu Mlingo wa 2000-3000 mg / tsiku amatha kusamutsidwa ku mankhwala Glucofage ® 1000 mg. Mlingo woyenera kwambiri ndi 3000 mg / tsiku, womwe umagawidwa pazigawo zitatu.

Ngati mukufuna kusintha kuti mumwe mankhwala ena a hypoglycemic, muyenera kusiya kumwa mankhwalawa ndikuyamba kumwa Glucofage ® mu mlingo womwe tafotokozawu.

Kuphatikiza kwa insulin

Kukwaniritsa bwino shuga wamagazi, metformin ndi insulin zitha kugwiritsidwa ntchito ngati mankhwala ophatikiza. Mlingo woyamba wa Glucofage ® ndi 500 mg kapena 850 mg kawiri / tsiku, pomwe mlingo wa insulin umasankhidwa potengera kuchuluka kwa shuga m'magazi.

Ana ndi achinyamata

Mwa ana azaka zapakati pa 10 ndi kupitirira, Glucofage ® ikhoza kugwiritsidwa ntchito ngati monotherapy komanso kuphatikiza insulin. Mulingo woyambira woyamba ndi 500 mg kapena 850 mg 1 nthawi / tsiku mukatha kudya kapena pakudya.Pambuyo masiku 10-15, mlingo uyenera kusinthidwa potengera kuchuluka kwa magazi. Mulingo wambiri watsiku ndi tsiku ndi 2000 mg, wogawidwa pamitundu iwiri.

Odwala okalamba

Chifukwa cha kuchepa kwa ntchito yaimpso, mlingo wa metformin uyenera kusankhidwa poyang'aniridwa kawirikawiri a impso function (kudziwa zomwe zili serum creatinine osachepera 2-4 pachaka).

Glucofage ® iyenera kumwedwa tsiku lililonse, osasokoneza. Ngati chithandizo chalekeka, wodwalayo ayenera kudziwitsa dokotala.

Bongo

Zizindikiro: mukamagwiritsa ntchito metformin pa mlingo wa 85 g (pafupipafupi 42,5 mlingo waukulu wa tsiku ndi tsiku), hypoglycemia siinawoneke, komabe, kukula kwa lactic acidosis kunadziwika.

Zofunikira kwambiri za bongo kapena zovuta zomwe zingagwirizane nazo zimatha kuyambitsa lactic acidosis.

Chithandizo: kuchoka kwa mankhwala Glucofage ®, kuchipatala mwachangu, kutsimikiza mtima kwa lactate m'magazi, ngati kuli koyenera, kuchitira mankhwala. Kuchotsa lactate ndi metformin m'thupi, hemodialysis imakhala yothandiza kwambiri.

Kuchita

Iodine-yokhala ndi radiopaque othandizira: motsutsana ndi kagwiritsidwe ntchito ka mphamvu yaimpso kwa odwala omwe ali ndi matenda osokoneza bongo, kafukufuku wama radiology ogwiritsa ntchito ayodini wokhala ndi radiopaque othandizira angayambitse kukula kwa lactic acidosis. Kuchiza ndi Glucofage ® kuyenera kuthetsedwa malinga ndi ntchito ya impso maola 48 asanafike kapena panthawi yomwe mayeso a X-ray amagwiritsa ntchito ayodini wokhala ndi ma radiopaque othandizira ndipo osayambiranso kale kuposa maola 48 atatha, pokhapokha ngati pakuwunika ntchito ya impso idadziwika kuti ndi yachilendo.

Ethanol - kuledzera kwadzaoneni, chiopsezo chokhala ndi lactic acidosis imachuluka, makamaka pankhani ya:

- kuperewera kwa zakudya m'thupi, zakudya zopatsa mphamvu zochepa,

Pogwiritsa ntchito mankhwalawa, mowa ndi mankhwala okhala ndi ethanol ayenera kupewedwa.

Kuphatikiza komwe kumafunikira kusamala

Kugwiritsa ntchito nthawi yomweyo danazol osavomerezeka kuti apewe hyperglycemic zotsatira za chomaliza. Ngati mankhwala a danazol akufunika ndipo atayimitsa koyamba, kusintha kwa mankhwala Glucofage ® kumafunikira motsogozedwa ndi kuchuluka kwa shuga m'magazi.

Chlorpromazine akamagwiritsa ntchito muyezo waukulu (100 mg / tsiku) amawonjezera kuchuluka kwa shuga m'magazi, kuchepetsa kutulutsa kwa insulin. Mankhwalawa antipsychotic ndipo atayimitsa chomaliza, kusintha kwa mankhwalawa kumafunikira motsogozedwa ndimagazi a shuga.

GCS yogwiritsira ntchito mwadongosolo komanso yakomweko kumachepetsa kulolera kwa glucose, kuonjezera kuchuluka kwa shuga m'magazi, nthawi zina kumapangitsa ketosis. Mankhwalawa corticosteroids ndipo atayimitsa kudya kwa chakumapeto, kusintha kwa mankhwala Glucofage ® kumafunika motsogozedwa ndi kuchuluka kwa shuga m'magazi.

Kugwiritsa ntchito munthawi yomweyo mankhwala a "loop" okodzetsa kungayambitse kukula kwa lactic acidosis chifukwa chakulephera kugwira ntchito kwaimpso. Glucofage ® sayenera kukhazikitsidwa ngati CC ili yochepera 60 ml / min.

Beta₂-adrenomimetics mu mawonekedwe a jakisoni amawonjezera kuchuluka kwa shuga m'magazi chifukwa chokondoweza kwa β₂-makampani. Poterepa, ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi. Ngati ndi kotheka, tikulimbikitsidwa kupereka insulin.

Pogwiritsa ntchito nthawi yomweyo mankhwala omwe ali pamwambawa, kuwunika pafupipafupi magazi a shuga kungafunike, makamaka kumayambiriro kwa chithandizo. Ngati ndi kotheka, mlingo wa metformin ungasinthidwe munthawi yamankhwala ndikatha.

Ma A inhibitors komanso mankhwala ena a antihypertensive amatha kuchepetsa magazi. Ngati ndi kotheka, mlingo wa metformin uyenera kusinthidwa.

Ndi munthawi yomweyo kugwiritsa ntchito mankhwala Glucofage ® ndi sulfonylurea zotumphukira, insulin, acarbose, salicylates, kukula kwa hypoglycemia ndikotheka.

Nifedipine imachulukitsa mayamwidwe ndi C_max metformin.

Mankhwala a Cationic (amiloride, digoxin, morphine, procainamide, quinidine, quinine, ranitidine, triamteren, trimethoprim ndi vancomycin) omwe amatulutsidwa mu renal tubules kupikisana ndi metformin kwa machitidwe oyendetsa ma tubular ndipo angayambitse kuchuluka kwa C_max.

Kodi ndingamwe mankhwalawo ndi mankhwala ena

Pochiza ndi metformin, wodwalayo ayenera kuuza adokotala za mavuto onse azaumoyo komanso kufunika kwa kumwa mankhwalawa. Izi zimapulumutsa pakukula kwamavuto pakamwa mankhwalawa omwe sangathe kumwa nthawi yomweyo.

Glucophage ndi yoletsedwa kumwa mankhwala ena ake. Izi zikuphatikiza:

• Osiyanasiyana omwe ali ndi ayodini
• ndizoletsedwa kumwa mowa kapena mankhwala okhala ndi mowa nthawi yomweyo ngati metformin. Kuphatikizika kumeneku kumatha kuyambitsa lactic acidosis.

Mankhwala omwe amachepetsa kuthamanga kwa glucophage:

• acarbose,
• insulin
• ACE zoletsa
• salicylates,
• zochokera sulfonylurea.

Njira zomwe zimachepetsa kutsitsa kwa shuga m'magazi a glucophage:

Glucophage analogues

Glucophage analogues ndi:

Kodi maubwino ndi chiyani poyerekeza ndi njira zina Glucofage:

• Pakakhala kusintha kwamwadzidzidzi m'magazi a shuga, mapiritsi a glucophage amatha kumwa 1 kamodzi patsiku,
• Poyerekeza ndi mankhwala ena okhala ndi Metformin, Glucofage imakhala ndi zotsatira zoyipa zochepa,
• misempha ya wodwala ndiyokhazikika,
• Mapiritsi satengedwa kuti muchepetse shuga, komanso kuti muchepetse thupi,
• pa mankhwala, kagayidwe kachakudya mthupi kamakhala bwino,
• mutamwa mankhwalawa, chiopsezo chokhala ndi matenda ashuga chimachepa.

Ndemanga za mankhwala

Malingaliro okhudza mapiritsi a Glucofage 1000 ndikuwunika kwa matenda ashuga komanso kunenepa kwambiri pakati pa odwala ndiosiyana - pali zabwino komanso zoipa. Makamaka kutsutsana za kugwiritsidwa ntchito bwino kwa mapiritsi kuli pakati pa odwala onenepa kwambiri. Gawo lina likuti mothandizidwa ndi mankhwalawa adakwanitsa kutsika mpaka 18 makilogalamu, ena akuti amakwanitsa kukhalabe ndi khola kwa nthawi yayitali. Pali malingaliro omwe Glucophage amathandizira ngakhale pakadakhala kuti chakudya chinalibe mphamvu.

Pali ndemanga yokhudza mavuto mutatha kumwa mapiritsi. Odwala akuti m'masiku oyamba amamva mseru komanso kupweteka m'mimba, ena anali ndi m'mimba. Koma patatha masiku ochepa, zizindikirazi zinazimiririka.

Pali ndemanga zingapo pa kusathandiza kwa mankhwalawa pochiza kunenepa. Koma anthu ambiri amati kuphunzitsidwa pafupipafupi mu masewera olimbitsa thupi ndi zakudya zamankhwala limodzi ndi kumwa Glyukofazh kunawonetsa zotsatira zabwino.

Komanso, odwala amawona mitengo yotsika mtengo yothetsera izi komanso kupezeka kwa magawo onse a anthu.

Umboni wa wodwala wazaka 51 wa Polina yemwe ali ndi matenda a shuga 2: “Dotolo adandiuza kuti ndilandire zaka 2 zapitazo, pomwe matenda ashuga adayamba kupita patsogolo. Pamenepo, ndinalibe nthawi yochita masewera, ngakhale panali mapaundi owonjezera. Ndinaona Glucofage yayitali mokwanira ndikuwona kuti kulemera kwanga kukuchepa. Ndinganene chimodzi - mankhwalawa ndi imodzi mwazinthu zabwino kwambiri zothandiza kuti shuga asinthe komanso kuti muchepetse thupi ”

Mankhwala Glucofage adziyambitsa yokha ngati chida chothandiza kuchepetsa shuga. Chitetezo panthawi ya chithandizo chotsimikizika ngati wodwalayo amatsatira zonse zomwe wapatsidwa ndikuchita ndi chilolezo cha dokotala. Glucofage imathandizira kukonza bwino kwa odwala komanso imathandizira kuchepa, ndipo mitengo yotsika mtengo m'mafakitoreya idzagwirizana ndi magulu onse a ogula.

Kanemayo pansipa amapereka zambiri mwatsatanetsatane pazinthu ndi mawonekedwe a metformin.

Glucophage wa matenda ashuga a 2

Chimodzi mwazomwe zimachepetsa shuga wamagazi ndikuthandizira kuchepetsa thupi ndi glucophage.Malinga ndi kafukufuku wofufuza, kumwa mankhwalawa kumachepetsa chiwerengero cha anthu omwalira ndi matenda ashuga ndi 53%, ndi 35% kuchokera kuphwanya myocardial komanso 39% kuchokera ku stroke.

Mawonekedwe ndi mawonekedwe a mankhwalawa

Metformin hydrochloride imawerengedwa kuti ndiyo chinthu chofunikira kwambiri pa mankhwalawa. Monga zina zowonjezera ndi:

• magnesium wakuba,
• povidone
• ulusi wa microcrystalline
• hypromellose (2820 ndi 2356).

Mankhwalawa amapezeka mu mawonekedwe a mapiritsi, mapiritsi okhala ndi Mlingo wa chinthu chachikulu chomwe amapezeka mu 500, 850 ndi 1000 mg. Mapiritsi a Lenticular a shuga a Glucophage ndi ofanana.

Adakutidwa ndi utoto wotetemera. Kumbali ziwiri, zoopsa zapadera zimayikidwa piritsi, pa imodzi mwa izo ndikuwonetsedwa.

Glucophage Kutalika kwa matenda ashuga

Glucophage Long ndi metformin yothandiza makamaka chifukwa cha zotsatira zake zanthawi yayitali.

Njira yapadera yothandizira mankhwalawa imapangitsa kuti zitheke kukwaniritsa zofananazo ngati mukugwiritsa ntchito metformin wamba, komabe, zotsatira zake zimapitiliza kwa nthawi yayitali, chifukwa chake, nthawi zambiri zimakhala zokwanira kugwiritsa ntchito Glucophage Long kamodzi patsiku.

Izi zimathandizira kwambiri kulolerana kwa mankhwalawo komanso moyo wa odwala.

Kukula kwapadera komwe kumagwiritsidwa ntchito popanga mapiritsi kumalola chinthu chogwira ntchito kuti chitha kulowa mu lumen yamtumbo motsatana komanso mofanananira, chifukwa chomwe glucose yolondola imasungidwa nthawi yonseyo, popanda kulumpha kapena madontho.

Kunja, piritsi imakutidwa ndi filimu yosungunula pang'onopang'ono, mkati mwake ndiye maziko okhala ndi zinthu za metformin. Pamene nembanemba imasungunuka pang'onopang'ono, chinthucho chimatuluka. Nthawi yomweyo, kupindika kwamatumbo ndi acidity sikumapangitsa zambiri pakumasulidwa kwa metformin; motere, zotsatira zabwino zimachitika mwa odwala osiyanasiyana.

Gwiritsani ntchito Glucofage Nthawi imodzi. Izi zimachotsa zosafunikira zimachitika m'matumbo am'mimba, zomwe zimachitika pakudya metformin, polumikizana ndi kuchuluka kwake kwakukhudzika m'magazi.

Njira yamachitidwe

Mankhwala ndi a gulu la Biguanides ndipo amapangidwa kuti achepetse magazi. Mfundo za glucophage ndikuti, pakuchepetsa kuchuluka kwa shuga, sizimabweretsa vuto la hypoglycemic.

Kuphatikiza apo, sizimakulitsa kupanga insulin ndipo sizikhudza kuchuluka kwa glucose mwa anthu athanzi. The peculiarity of the mechanism of glucophage based on the chakuti imathandizira chidwi cha zolandilira ku insulin ndikuyambitsa kukonzanso kwa shuga ndi minyewa ya minofu.

Amachepetsa njira yodzikundikira glucose m'chiwindi, komanso chimbudzi cha chakudya ndi chimbudzi. Imakhala ndi phindu lambiri pa metabolism yamafuta: imachepetsa kuchuluka kwa cholesterol, triglycerides ndi lipoproteins yotsika.

The bioavailability wa malonda si ochepera 60%. Imalowetsedwa mwachangu kudzera m'makoma am'mimba ndipo kuchuluka kwakukulu kwa zinthu zomwe zili m'magazi amalowa maola awiri ndi theka atatha kutsata pakamwa.

Chinthu chogwira ntchito sichikhudza mapuloteni am magazi ndipo chimafalikira mwachangu kuma cell a thupi. Simalinganizidwa ndi chiwindi ndipo amachotsa mkodzo. Pali chiopsezo chopinga cha mankhwala mu minyewa mwa anthu omwe ali ndi vuto laimpso.

Ndani amene sayenera kumwa mankhwalawa?

Odwala ena omwe amatenga glucophage amadwala matenda oopsa - lactic acidosis. Izi zimayamba chifukwa cha kuchuluka kwa lactic acid m'magazi ndipo nthawi zambiri zimachitika ndi anthu omwe ali ndi vuto la impso.

Anthu ambiri omwe ali ndi matenda amtunduwu, madokotala samapereka mankhwala.Kuphatikiza apo, pali zinthu zina zomwe zingakulitse mwayi wopeza lactic acidosis.

Izi zimagwira ntchito kwa odwala omwe:

• mavuto a chiwindi
• kulephera kwa mtima
• pali mankhwala osagwirizana,
• mimba kapena mkaka wa m'mimba,
• opaleshoni imakonzedwa posachedwa.

Zotsatira zoyipa Glucophage

Nthawi zina, glucophage imatha kubweretsa vuto lalikulu - lactic acidosis. Izi zimachitika kawirikawiri mwa anthu omwe ali ndi vuto la impso.

Malinga ndi ziwerengero, pafupifupi munthu m'modzi mwa odwala 33,000 omwe amatenga Glucofage kwa chaka chimodzi ali ndi vutoli. Izi sizachilendo, koma zitha kupha anthu 50% omwe ilimo.

Ngati mukuwona zizindikiro zilizonse za lactic acidosis, muyenera kusiya kumwa mankhwalawo ndi kufunsa dokotala.

Zizindikiro za lactic acidosis ndi:

• kufooka
• kupweteka kwa minofu
• mavuto kupuma
• kumva kuzizira
• chizungulire
• kusintha kwadzidzidzi kwamtima - tachycardia,
• kusasangalala m'mimba.

Zotsatira zoyipa za kumwa Glucophage:

Zotsatira zoyipa izi zimatha kutha ndikugwiritsidwa ntchito kwa nthawi yayitali. Pafupifupi 3% ya anthu omwe amamwa mankhwalawa amakhala ndi zipatso zachitsulo akamamwa mankhwalawo.

Ndi mankhwala ena ati omwe amakhudza mphamvu ya glucophage?

Lankhulani ndi dokotala wanu za kumwa mankhwalawa nthawi yomweyo monga glucophage.

Sizikulimbikitsidwa kuphatikiza mankhwalawa ndi digoxin kapena furosemide.

Kugwiritsira ntchito kwina kwa mankhwalawa ndi glucophage kungayambitse matenda a shuga (hypoglycemia), omwe ndi:

• phenytoin
• mapiritsi othandizira kubereka kapena mankhwala olowa m'mimba,
• zakudya zam'mapiritsi kapena mankhwala a mphumu, chimfine kapena chifuwa,
• mapiritsi a diuretic
• mtima kapena mankhwala oopsa,
• niacin (Advicor, Niaspan, Niacor, Simcor, Srb-niacin, etc.),
• phenothiazines (Compazin et al.),
• mankhwala a steroid (prednisone, dexamethasone ndi ena),
• mankhwala a mahomoni a chithokomiro cha chithokomiro (Synthroid ndi ena).

Mndandandawu suti wathunthu. Mankhwala ena amatha kuwonjezera kapena kuchepetsa mphamvu ya glucophage pakuchepetsa shuga.

Mafunso Ofunsidwa Kawirikawiri

• Chimachitika ndi chiani ndikaphonya mlingo?

Imwani mankhwala omwe mwasowa mukangokumbukira (onetsetsani kuti mumwa mankhwalawo ndi chakudya). Lumikizani mlingo womwe mwasowa ngati nthawi yotsiriza yomwe mwakonzekererayi ndiyifupi. Sikulimbikitsidwa kumwa mankhwala ena owonjezereka kuti mupange mlingo womwe mwasowa.

• Chimachitika ndi chiyani ngati mumagwiritsa ntchito bongo mopitirira malire?

Mankhwala osokoneza bongo a metformin angayambitse kukula kwa lactic acidosis, yomwe ikhoza kupha.

• Ndiyenera kupewa chiyani ndikamamwa glucophage?

Pewani kumwa mowa. Imachepetsa shuga m'magazi ndipo imatha kukulitsa chiopsezo cha lactic acidosis mukamatenga Glucofage.

Glucophage kuchokera ku matenda ashuga: ndemanga

Kupanga chithunzithunzi chazomwe chimayambira matenda a shuga motsogozedwa ndi glucophage, kafukufuku adachitika pakati pa odwala. Kuti muchepetse zotsatira, ndemanga zidagawika m'magulu atatu ndipo cholinga chachikulu chidasankhidwa:

Ndidapita kwa dotolo ndili ndi vuto loti ndizichedwa kulemera msanga ngakhale kuti ndimadya komanso ndimachita masewera olimbitsa thupi, nditapimidwa kuchipatala ndidapezeka kuti ndili ndi insulin kwambiri komanso hypothyroidism, yomwe idapangitsa vuto la kulemera. Dokotala wanga anandiuza kuti ndimwe manformin pa mlingo waukulu wa 850 mg katatu pa tsiku ndikuyamba kulandira mankhwala a chithokomiro. Pakupita miyezi itatu, kulemera kunapangitsa kuti insulin ipangidwe. Ndinkakonzekera kutenga Glucofage kwa moyo wanga wonse.

Kutsiliza: kugwiritsa ntchito glucophage pafupipafupi kumapereka zotsatira zabwino ndi kuchepa kwakukulu.

Glucophage amatengedwa kawiri patsiku ndi mkazi wake. Ndasowa kangapo.Ndinachepetsa magazi anga pang'ono, koma mavuto ake anali oopsa. Chepetsani mlingo wa metformin. Pamodzi ndi zakudya komanso masewera olimbitsa thupi, mankhwalawa adachepetsa shuga m'magazi, ndinganene, 20%.

Kutsiliza: kuthyola mankhwala kumayambitsa mavuto.

Woikidwa pafupi mwezi wapitawu, wapezeka posachedwapa ndi matenda a shuga 2. Adatenga milungu itatu. Zotsatira zoyipa sizinali zofooka poyamba, koma zidakulirakulira mpaka ndidakafika kuchipatala. Inayimitsidwa kutenga masiku awiri apitawa ndikupezanso mphamvu.

Kutsiliza: tsankho la munthu payekha lomwe limagwira

Zotsatira zoyipa

Kutsimikiza kwamafupipafupi a mavuto: pafupipafupi (≥1 / 10), nthawi zambiri (1001/100, ® angagwiritsidwe ntchito ngati monotherapy komanso kuphatikiza ndi insulin. Nthawi zonse mlingo wa 500 mg kapena 850 mg 1 nthawi / tsiku pambuyo Pakadutsa masiku 10-15, mlingo uyenera kusinthidwa molingana ndi kuchuluka kwa shuga m'magazi. Mlingo wambiri watsiku ndi tsiku ndi 2000 mg, wogawidwa mu Mlingo wa 2-3.

Malangizo apadera

Lactic acidosis ndizosowa koma zowopsa (kuchuluka kwaimfa pakalibe chithandizo chamankhwala mwadzidzidzi) zomwe zingachitike chifukwa cha kuphatikizika kwa metformin. Milandu ya lactic acidosis mutatenga metformin imapezeka makamaka mwa odwala omwe ali ndi matenda osokoneza bongo omwe amalephera kwambiri aimpso.

Zina zokhudzana ndi chiopsezo ziyenera kuganiziridwanso, monga matenda a shuga oopsa, ketosis, kusala kudya kwa nthawi yayitali, uchidakwa, kulephera kwa chiwindi, komanso vuto lililonse lomwe lingakhale ndi hypoxia. Izi zitha kuthandiza kuchepetsa zochitika za lactic acidosis.

Kuopsa kwa lactic acidosis kuyenera kuganiziridwanso ngati zizindikiro zosadziwika, monga kupsinjika kwa minofu, limodzi ndi zizindikiro za dyspeptic, kupweteka kwam'mimba komanso asthenia yayikulu. Lactic acidosis imadziwika ndi kufupika kwa acidotic, kupweteka kwam'mimba komanso hypothermia, kenako kutsekeka.

Diagnostic labotale magawo ndi kuchepa kwa magazi pH (® sikuyambitsa hypoglycemia, chifukwa chake, sizikhudza kuthekera kuyendetsa magalimoto ndi machitidwe. Komabe, odwala ayenera kuchenjezedwa za kuopsa kwa hypoglycemia mukamagwiritsa metformin kuphatikiza mankhwala ena a hypoglycemic (kuphatikiza mankhwala ena a hypoglycemic) zotumphukira sulfonylurea, insulin, repaglinide).

Glucophage 1000 - momwe angatengere kuti muchepetse kunenepa, panthawi yomwe muli ndi pakati komanso matenda a shuga, Mlingo, malingaliro ndi mtengo

Kuti achulukitse kagayidwe mu mtundu wachiwiri wa matenda ashuga, endocrinologists amalamula Glucofage 1000, yomwe iyenera kuphatikizidwa ndi chakudya, kwa odwala awo. Ena amati mankhwalawa amatha kugwiritsidwa ntchito pochepetsa chidwi cha anthu komanso kuwonda, koma izi ndizowopsa chifukwa cha zovuta zina zamthupi zambiri. Phunzirani momwe mungagwiritsire ntchito Glucophage, kapangidwe kake ndi zotsutsana ndi ziti.

Mankhwala Glucophage mu shuga amapatsidwa kwa odwala omwe amapezeka ndi matenda a shuga a mtundu woyamba kapena wachiwiri. Glucofage 1000 yadzikhazikitsa yokha ngati njira yothandiza yomwe wodwala angakwaniritsire kuchepa kwa shuga m'magazi, osatsogolera ku hypoglycemia.

Mankhwalawa ndi otchuka pochiza kunenepa, chifukwa amathandizira kuchepetsa kunenepa kwambiri. Katunduyu ndi chifukwa chogwiritsa ntchito mankhwalawa ngati njira yochepetsera thupi, othamanga kuti "awume" thupi. Kugwiritsa ntchito molakwika mankhwalawa kumatha kuvulaza kwambiri.

Mankhwala amapezeka piritsi. Piritsi looneka ngati mawonekedwe limakulungidwa ndi chipolopolo chomwe chimakhala ndi utoto woyera. Kapangidwe kake ndi biconvex, pamakhala chiopsezo mbali zonse ziwiri. The mankhwala:

Pharmacodynamics ndi pharmacokinetics

Zomwe zimagwiritsidwa ntchito ndi mankhwala - metformin imakhala ndi hypoglycemic, yomwe imawonetsedwa mu kuchepa kwa hyperglycemia.Mankhwalawa amatha kutsitsa shuga m'magazi onse masanawa ndipo atatha kudya.

Limagwirira zake chifukwa cha mphamvu ya mankhwalawo kuletsa gluconeogeneis, glycogenolysis, kuwonjezera insulin kumva ndi kuchepetsa mayamwidwe a shuga ndi m'mimba thirakiti. Izi zimabweretsa kuchiritsa.

Kuphatikizika kwa izi kumabweretsa kutsika kwa glucose m'chiwindi ndi kukondoweza kwa kukonza kwake ndi minofu.

The bioavailability pamene amatengedwa ndi pafupifupi 50-60%. mankhwalawa amatha kutsika kumapuloteni a plasma, omwe amalowa m'maselo ofiira a m'magazi. Mankhwala omwe amalandiridwa samapukusidwa, amatsitsidwa ndi impso komanso pang'ono m'matumbo. Kuchotsa theka moyo ndi pafupifupi 6.5 maola. Odwala omwe ali ndi vuto losakhazikika la impso, kuchepa kwa mayamwidwe a metformin kumawonedwa.

Glucophage imakhala ndi chizindikiro chimodzi chogwiritsidwa ntchito, chovomerezedwa ndi mankhwala ovomerezeka. Kugwiritsa ntchito mankhwalawa pofuna kuchepetsa thupi kuli pachiwopsezo chanu. Mankhwalawa amagwiritsidwa ntchito pochiza matenda a shuga a mtundu wachiwiri.

Makamaka kugwiritsidwa ntchito kumalimbikitsidwa kwa anthu omwe ali ndi kunenepa kwambiri, bola palibe zotsatira zamankhwala olimbitsa thupi komanso maphunziro olimbitsa thupi.

Akuluakulu ndi ana atatha zaka khumi amagwiritsa ntchito mankhwalawa ngati monotherapy kapena pamodzi ndi insulin malinga ndi dongosolo lomwe adokotala adapereka.

Glucophage iyenera kumwedwa pakamwa popanda kutafuna, kutsukidwa ndi madzi. Ndi bwino kudya ndi chakudya kapena mukatha kudya. Mlingo woyamba wa metformin wa akulu ndi 500 mg kawiri kapena katatu / tsiku.

Mukasinthira kukonza mankhwala, mankhwalawa amayamba 1500 mg mpaka 2000 mg / tsiku. Vutoli limagawidwa mu Mlingo wambiri kapena itatu kuti lipange boma lolimba pamimba. Mlingo wapamwamba ndi 3000 mg.

Kusintha kuti muthandizike ndi mankhwala ena a hypoglycemic kumapangitsa kuti pakhale chachiwiri.

Kuphatikiza mankhwala ndi insulini kumaphatikizira kuchuluka kwa insulini m'magazi. Kuvomerezedwa kwa mankhwalawa ndi ana, kuyambira zaka 10, kumachitika malinga ndi dongosolo la 500 mg kawiri kapena katatu / tsiku.

Pambuyo masiku 10-15, mlingo umasinthidwa malinga ndi kusintha kwa shuga m'magazi. Mlingo wovomerezeka wopezeka ndi 2000 mg / tsiku.

Kwa anthu okalamba, mankhwalawa amalembedwa ndi dokotala, poganizira momwe impso zilili.

Glucophage pa nthawi yapakati

Zowona za mimba ziyenera kudziwa kuthetsedwera kwa mankhwalawa Glucofage 1000. Ngati kutenga pakati kumangokonzekera, ndikofunikira kupereka kuthetseratu kwa mankhwalawa. Njira ina ya metformin ndiyo mankhwala a insulin oyang'aniridwa ndi dokotala. Mpaka pano, palibe chidziwitso cha momwe mankhwalawa amakhudzirana ndi mkaka wa m'mawere, chifukwa chake, kugwiritsa ntchito Glucofage ndizoletsedwa mukamayamwitsa.

Mankhwala Glucofage 1000 ndi ma biguanides ena amapangidwa kuti athandize odwala matenda ashuga, mankhwala awo omwe amapanga metformin amachepetsa shuga la magazi, pomwepo amachepetsa mafuta m'thupi. Katunduyu ndi wofunikira kwambiri kwa odwala matenda ashuga, chifukwa nthawi zambiri amakhala ndi vuto lolemera. Anthu athanzi safuna kumwa mankhwala popanda kufunsa dokotala, malinga ndi ndemanga iyi ili ndi zovuta zambiri.

Ntchito za metformin pakuchepetsa thupi ndizo: kubwezeretsa kagayidwe ka lipid, kuchepetsa kuchepa kwa chakudya ndi njira yosinthira metabolites awo kukhala mafuta, kutsata kwa cholesterol "yoyipa", kuponderezedwa kwachilengedwe chifukwa cha kuphatikizidwa kwa kupanga insulin. Ngati dokotala wakulolezani kudya Glucofage chifukwa cha kunenepa, ndiye kuti muyenera kutsatira malamulo osavuta ovomerezeka:

• kupatula pa zakudya zotsekemera ndi zomwe zimapangitsa shuga.
• kuphatikiza chakudya ndi fiber, nyemba, ufa wongokhala, masamba,
• tsatirani zakudya zamafuta ochepa (osapitirira 1800 kcal / tsiku), kusiya mowa ndi kusuta,
• kuchita zolimbitsa thupi
• kumwa Glucofage 1000 pa mlingo wa 1500 mg / tsiku zakudya zitatu ola limodzi musanadye chakudya kwa masiku 18-20, mutatha miyezi iwiri yopuma.

Kuyanjana kwa mankhwala osokoneza bongo

Si mankhwala onse omwe angaphatikizidwe ndi Glucophage. Pali mitundu yoletsedwa komanso yosavomerezeka:

• poyizoni woledzera umadzetsa lactic acidosis, ngati munthu sakudya mokwanira, amakhala ndi vuto la chiwindi.
• sikulimbikitsidwa kuphatikiza chithandizo cha Danazol ndi Glucophage chifukwa cha zotsatira za hyperglycemic,
• Mlingo waukulu wa chlorpromazine umachulukitsa kuchuluka kwa shuga, kusintha kwa mankhwala kumafunikira, komanso ma antipsychotic,
• loop diuretics imabweretsa lactic acidosis, beta-adrenergic agonists amalimbikitsa shuga, insulin ndiyofunikira,
• antihypertgency othandizira amachepetsa hyperglycemia,
• zotumphukira za sulfonylurea, insulin, acarbose ndi salicylates zimayambitsa hypoglycemia,
• Nifedipine imawonjezera mayamwidwe a metformin, kuyendetsa shuga ndikofunikira,
• mankhwala a cationic (Digoxin, Morphine, Quinidine, Vancomycin) amonjezera nthawi ya mayamwidwe a metformin.

Migwirizano yogulitsa ndikusunga

Mankhwala amaperekedwa ndi mankhwala, osungidwa m'malo osagwiritsidwa ntchito ndi ana kwa kutentha kosaposa 25 digiri. Moyo wa alumali ndi zaka zitatu.

Mutha kusintha mankhwalawo ndi othandizira omwe ali ndi chinthu chomwecho, kapena ndi mankhwala omwe ali ndi mphamvu yomweyo mthupi. Glucophage analogues ingagulidwe muma drug mu mapiritsi kapena makapisozi a pakamwa makonzedwe:

• Metformin
• Glucophage Long 1000,
• Glucophage 850 ndi 500,
• Siofor 1000,
• Metformin teva
• Bagomet,
• Glycometer
• Dianormet
• Diaformin.

Glucofage mtengo 1000

Mutha kugula Glucophage kokha m'masitolo, chifukwa mankhwala ochokera kwa dokotala amafunikira kuti mugule. Mtengo wake udzasiyana malinga ndi kuchuluka kwa mapiritsi okhala m'mpaketi. M'madipatimenti opanga mankhwala ku Moscow ndi St. Petersburg, mtengo wa mankhwalawo udzakhala:

Ndili ndi matenda ashuga a 2, motero ndimafunikira ndalama kuti ndikhalanso ndimagazi. Mwana wanga wamkazi adandigulira mapiritsi a Glucofage omwe adadza kwa ine. Amayenera kuledzera kawiri pa tsiku kuti shuga ikhale yachilendo. Mankhwalawa aledzera bwino, samayambitsa mavuto. Ndakhutira, ndimakonzekera kumwa iwo mopitilira.

Potsatira mayeso omaliza a zamankhwala, adawonetsa gawo loyamba la matenda ashuga a 2. Ndibwino kuti sioyambayo, koma zikadakhala zofunika kupaka insulin mpaka kumapeto kwa moyo. Madokotala amandiuza mapiritsi a glucophage. Adandiuza kuti ndimwe kwa miyezi isanu ndi umodzi, ndiye kuti ndikayezetsa, ndipo ngati pali chilichonse, andipititsa ku mankhwala ena - Kutalika, omwe muyenera kumwa kamodzi patsiku. Ndikumwa, ndimakonda momwe zimakhalira.

Ndakhala ndikudwala matenda ashuga kwa chaka chachiwiri tsopano. Ndili ndi mtundu wachiwiri - wosadalira insulini, chifukwa chake ndimatha kugwiritsa ntchito mankhwala a glycemic. Ndimamwa Glucophage Long - Ndimakonda kuti angagwiritsidwe ntchito kamodzi patsiku, zotsatira zake ndizokwanira kwa tsiku. Nthawi zina ndimayamba kusanza ndikamwa mankhwalawa, koma zimadutsa mwachangu. Kupanda kutero, amandiyenera.

Kuchokera kwa mzanga, ndinamva kuti amachepetsa Glyukofage. Ndinaganiza zoyang'ana ndemanga zambiri za chida ichi, ndipo ndinadabwitsidwa ndi momwe zimagwirira ntchito. Zinali zovuta kupeza - mapiritsi amagulitsidwa ndimankhwala, koma ndinatha kuwagula. Anatenga ndendende milungu itatu, koma sanawone momwe zimachitikira. Sindinali wokondwa, kuphatikiza apo panali kufooka wamba, ndikhulupilira kuti palibe vuto.

Glucophage - malangizo, mtengo, ndemanga ndi analogi wa mankhwala

Glucophage - mankhwala omwe amachepetsa shuga pamlomo, ali m'gulu la Biguanides.

Imachepetsa kukana kwa insulini pakukulitsa mphamvu ya insulini ya zotumphukira zolimbitsa thupi, imathandizira kukoka kwa minofu, kuletsa gluconeogeneis, ndikuchepetsa kuyamwa kwa matumbo.

Limasinthasintha kagayidwe ka lipid, kuchepetsa kuchuluka kwa cholesterol, LDL ndi triglycerides m'magazi.

Zochizira

"Glucophage" ndi mankhwala ochepetsera shuga pakuchita pakamwa, gawo lomwe limatchedwa metformin (lomwe limachokera ku biguanides).

Mankhwalawa ali ndi vuto la hypoglycemic, amalimbikitsa kugwiritsidwa ntchito kwa glucose ndi minofu minofu, kumawonjezera chidwi cha zotumphukira kuti insulin, chifukwa chomwe amachepetsa kukana insulini.

Imalepheretsa mayamwidwe am'matumbo m'matumbo, imalepheretsa gluconeogeneis wa hepatic, imagrate metabolid, kuchepetsa zomwe zimakhala ndi triglycerides, cholesterol ndi LDL m'magazi. Sichikukhudzana ndi katemera wa pancreatic wa insulin ndipo sikuti kumabweretsa hypoglycemia.

Glucophage ndi mankhwala othandizira odwala matenda a shuga 2 omwe amawonjezera shuga (makamaka osagwirizana ndi insulin) makamaka kwa odwala omwe ali ndi kunenepa kwambiri, chifukwa chosowa chotsatira cha kuphatikiza kwa mankhwala othandizira pakudya ndi zolimbitsa thupi. Itha kuperekedwa kwa odwala omwe ali ndi vuto la matenda a shuga 1 kuti achepetse Mlingo wa insulin (makamaka kunenepa kwambiri ndi kukula kwa insulin kukana).

Njira yogwiritsira ntchito

Mlingo, regimen ndi nthawi yayitali yamankhwala zimadalira kuchuluka kwa kubwezeretsa kwa kagayidwe kazakudya ndipo amatsimikiza ndi dokotala. Glucophage imatengedwa pamlomo, pakudya kapena pambuyo pake.

Nthawi zambiri, chithandizo chimayamba ndi 500-1000 mg patsiku, pakatha milungu iwiri, mankhwalawa amawonjezeka pang'onopang'ono mpaka kubwezeretsa kwokhazikika kwa hyperglycemia kumatheka.

Mulingo wambiri watsiku ndi tsiku sayenera kupitirira 3000 mg ya metformin patsiku la akulu ndi 1000 mg ya metformin patsiku la okalamba.

Zotsatira zoyipa

Mukamamwa Glucophage, zizindikiro za dyspepsia (flatulence, nseru, kukoma kwazitsulo mkamwa, kusanza, kutsekula m'mimba, kusowa kwa chakudya) nthawi zina kumawonekera.

Kuti muchepetse zizindikiro zotere, antispasmodics, kukonzekera kwa atropine ndi mankhwala, tsiku lililonse mankhwalawa amatha kumwa mu Mlingo wa 2-3, pakudya. Thupi lawo siligwirizana, lactic acidosis (chizindikiro chosiya kugwiritsa ntchito mankhwalawa) ndizotheka.

Ndi chithandizo cha nthawi yayitali ndi Glucofage, odwala ena amayamba kuchepa magazi m'thupi.

Mu nkhani ya bongo, pali kuthekera kwakukulu kwa kukhala lactic acidosis, omwe amayamba kupweteka minofu, nseru, kufooka, kusanza, kupweteka m'mimba, kutsegula m'mimba, matenda oopsa. Pankhaniyi, mankhwalawa ayenera kusiyidwa pomwepo, wodwalayo akuwonetsedwa kuchipatala komanso kukomoka (hemodialysis).

CHOKONZEDWA MALO OGULITSA

Kodi Glucophage ndi Glucophage Kutalika Kabwino: Kuunika Mwazotheka ndi Malangizo Ogwiritsira Ntchito

Nthawi zina zimakhala zovuta kuti akatswiri asankhe njira yoyenera yodwala matenda ashuga. Pofuna kuti asakhale osokoneza, amachita zinthu modekha pazizindikiro zamagazi ndipo alibe zotsatirapo zake.

Glucophage ndi amodzi mwa mankhwala otere. Ndilo gulu la Biguanides.

Chimodzi mwamaubwino apakati a mankhwalawa ndi kuchepetsa hyperglycemia popanda chitukuko cha hypoglycemia. Muthanso kuwerengera kusowa kwa kukondoweza kwa insulin katulutsidwe. Kenako, Glucophage ndi Glucophage Long, kuwunikira ndi malangizo awo zithandizidwanso mwatsatanetsatane.

Glucofage kuti muchepetse shuga

Mankhwalawa amatha kugwiritsidwa ntchito pokhapokha ngati akuwuzani dokotala.

Amagwiritsidwa ntchito makamaka pochiza matenda a shuga 2. Amadziwikanso nthawi zina kwa odwala omwe ali ndi kunenepa kwambiri komanso osagwiritsa ntchito bwino mankhwala othandizira kudya komanso kuchita masewera olimbitsa thupi.

Mankhwalawa amagwiritsidwa ntchito ndi akuluakulu monga monotherapy, kapena kuphatikiza ena othandizira pakamwa.

Dziwani kuti ngati zili ndi shuga m'magazi, mankhwalawa sawachepetsa.

Glucophage imakhala yofatsa kwambiri ya hypoglycemic, imapangitsa kuti shuga azikhala ndi shuga pamlingo woyenera.ads-mob-1

Kugwiritsa ntchito moyenera

Kwa wodwala aliyense, muyezo ndi momwe amamugwiritsira ntchito amasankhidwa payekha, kutengera mawonekedwe a thupi, zaka komanso mapikidwe ake.

Odwala omwe ali m'gululi amalamula kuti apatsidwe mankhwala onse a monotherapy komanso zovuta.

Mlingo woyambirira wa Glucophage nthawi zambiri umakhala 500, kapena mamiliyoni 850, wogwiritsa ntchito pafupipafupi katatu patsiku musanadye kapena mutatha kudya.

Glucophage mapiritsi 1000 mg

Ngati ndi kotheka, kuchuluka kwake kungasinthidwe pang'onopang'ono, ndikuwonjezera malinga ndi kuchuluka kwa shuga m'magazi a wodwala. Mlingo wokonzanso wa Glucofage nthawi zambiri amakhala mamililita 1,500-2,000 patsiku.

Pofuna kuchepetsa zoyipa zilizonse zomwe zingachitike kuchokera m'matumbo am'mimba, kuchuluka kwa tsiku ndi tsiku kumagawidwa ma Mlingo angapo. Mafuta okwanira mamililita 3000 angagwiritsidwe ntchito.

Mlingo umalimbikitsidwa kuti uzisinthidwa pang'onopang'ono kuti mankhwalawa athe kusintha.

Odwala omwe amalandila metformin mu mlingo wa 2-3 magalamu patsiku, ngati kuli kotheka, amatha kusamutsidwa kugwiritsa ntchito mankhwala a Glyukofazh 1000 milligrams. Pankhaniyi, kuchuluka kwakukulu ndi mamiligalamu 3000 patsiku, omwe amayenera kugawidwa m'magawo atatu .ads-mob-2

Kuphatikiza kwa insulin

Kuti tikwaniritse kuwongolera kwa glucose, metformin ndi insulin amagwiritsidwa ntchito ngati gawo limodzi la mankhwala.

Mlingo woyambirira ndi 500, kapena mamiligalamu 850, wogawidwa ndi 2-3 patsiku, ndipo kuchuluka kwa insulini kuyenera kusankhidwa potengera kuchuluka kwa shuga m'magazi.ads-mob-1

Ana ndi achinyamata

Kwa odwala omwe msinkhu wawo umaposa zaka 10, kugwiritsa ntchito Glucophage mwanjira ya monotherapy nthawi zambiri kumadziwika.

Mlingo woyambirira wa mankhwalawa umachokera ku 500 mpaka 850 mamililita 1 nthawi patsiku, kapena pakudya.

Pakatha masiku 10 kapena 15, kuchuluka kwake kuyenera kusinthidwa kutengera mphamvu za shuga m'magazi.

Mlingo woyenera wa tsiku ndi tsiku wa mankhwalawa ndi ma milligram 2000, omwe ayenera kugawidwa mu Mlingo wa 2-3.

Odwala okalamba

Pankhaniyi, chifukwa cha kuchepa kwa impso, Mlingo wa Glucophage uyenera kusankhidwa payekhapayekha.

Pambuyo popanga ndi kutsimikizira njira yothandizira, mankhwalawa amayenera kumwa tsiku lililonse osasokoneza.

Akamaliza kugwiritsa ntchito mankhwalawa, wodwalayo ayenera kudziwitsa adotolo za.ads-mob-2

Kodi ndizoyenera kuyesa?

Glucophage ndi mankhwala omwe ali ndi zovuta zoyipa zomwe zimagwiritsidwa ntchito molakwika.

Osamagwiritsa ntchito mankhwala anu mosadwala. Nthawi zambiri mankhwalawa amadziwika kuti ndi "ochepa", koma amaiwala kumveketsa "shuga". Ndikofunika kudziwa izi musanayambe mankhwala a Glucofage.

Zoyeserera ziyenera kusiyidwa, chifukwa kupatuka kulikonse kuchokera pazomwe zingatsimikizidwe kungakhudze kwambiri thanzi.

Mtengo wa Glucophage m'masitolo aku Russia ndi:

• mapiritsi a milligram 500, zidutswa 60 - ma ruble 139,
• mapiritsi a mamililita 850, zidutswa 60 - ruble 185,
• mapiritsi a mamililita 1000, zidutswa 60 - ma ruble 269,
• mapiritsi a milligram 500, zidutswa 30 - ma ruble 127,
• mapiritsi a mamililita 1000, zidutswa 30 - ma ruble 187.

Ndemanga za odwala ndi madokotala za mankhwala Glucofage:

• Alexandra, dokotala wazamankhwala: "Cholinga chachikulu cha Glucophage ndikuchepetsa kwambiri magazi. Koma posachedwa, chizolowezi chogwiritsa ntchito chida chocheperako chikukula kwambiri. Ndizosatheka kuchitira chithandizo chodziyimira palokha ndi Glucophage, ziyenera kuchitika pokhapokha ngati akuwuzani katswiri."Mankhwalawa ali ndi zotsutsana zambiri, ndipo zingayambenso kusokoneza ntchito za kapamba."
• Pavel, endocrinologist: “Pochita izi, nthawi zambiri ndimalamula kuti glucophage akhale ndi odwala. Awa anali odwala matenda ashuga, omwe nthawi zina amakhala owonda kwambiri onenepa kwambiri. Mankhwalawa ali ndi zovuta zoyipa, chifukwa chake, popanda kuyang'aniridwa ndi dokotala, ndithudi sizingatheke. Kulandila kungayambitse ngakhale kupweteka, koma malinga ndi zomwe ndawonapo, kufunitsitsa kuchepetsa thupi, ngakhale zoopsa zotere, tsoka, sikuletsa anthu. Ngakhale izi, ndimaona kuti chithandizo cha Glucophage ndi chothandiza kwambiri. Chofunikira ndikulifikira moyenera ndikuganizira momwe thupi la wodwalayo lilili, ndiye kuti lingathandize kuti magazi asungunuke ndikuchotsa mapaundi owonjezera. ”
• malonda-pc-4Maria, woleza mtima: “Chaka chapitacho, ndinapezeka ndi matenda a shuga 2. Ndidakwanitsa kuyesa mitundu yambiri ya mankhwala omwe adokotala adandipangira, kuphatikizapo Glucofage. Mosiyana ndi mankhwalawa ofanana, atagwiritsidwa ntchito nthawi yayitali, mankhwalawa sanali oledzera ndipo amagwirabe ntchito bwino. Ndipo zomwe adadzipangira zidamveka kale pa tsiku loyamba. Kusunga kuchuluka kwa shuga pakati pa mulingo woyenera kumakhala kofatsa, popanda kudumpha mwadzidzidzi. Kuchokera pa zomwe ndakumana nazo, nditha kunena kuti sanandibweretsere zovuta zilizonse, kupatula nthawi yovuta kusanza pang'ono. Chikhumbo ndi kulakalaka kwa maswiti zachepa kwambiri. Kuphatikiza apo, ndikufuna kudziwa zotsika mtengo, ngakhale mankhwalawa amapangidwa ndi France. Mwa mfundo zoyipa, ndikufuna kunena za kukhalapo kwa zotsutsana zambiri ndi zoyipa zina. Ndili wokondwa kuti sanandigwire, koma ndimalangiza kuti asagwiritse ntchito Glucofage popanda nthawi. ”
• Nikita, wodwala: "Kuyambira ndili mwana" ndinali wokhathamira ", ndipo ziribe kanthu momwe ndimadyera, kunenepa kumatsalira, koma nthawi zonse kumabweranso, nthawi zina ngakhale kangapo. Atakula, pamapeto pake adaganiza zotengera endocrinologist ndi vuto lake. Adandifotokozera kuti popanda kugwiritsa ntchito mankhwala osokoneza bongo zingakhale zovuta kupeza zotsatira zokhazikika komanso zabwino. Kenako anzanga a Glucophage adachitika. ” Mankhwalawa ali ndi zovuta zambiri, mwachitsanzo, contraindication ndi zovuta, koma zonse zidayenda bwino moyang'aniridwa ndi dokotala. Mapiritsi, mwachidziwikire, ndi osasangalatsa pakumveka komanso osamasuka kugwiritsa ntchito, nthawi ndi nthawi mseru komanso kupweteka m'mimba. Koma mankhwalawa adandithandizira bwino pakuchepetsa thupi. Kuphatikiza apo, zidapezeka kuti shuga yanga yamagazi idachulukitsidwa pang'ono, ndipo mankhwalawo adachita ntchito yayikulu kuiphatikiza. Mtengo wotsika mtengo nakondweretsanso. Zotsatira zake, nditatha chithandizo cha mwezi umodzi, ndidataya makilogalamu 6, ndipo zotsatira zabwino za mankhwalawa zidakhazikika kwa nthawi yayitali "
• Marina, wodwala: "Ndili ndi matenda ashuga, adotolo andipangira mankhwala a Glucofage. Nditawerenga ndemanga, ndidadabwa kwambiri kuti anthu ambiri amagwiritsa ntchito mankhwalawa pofuna kuchepetsa thupi. Amapangidwira zochizira matenda oopsa monga matenda ashuga, ndipo sangathe kuwagwiritsa ntchito mwanjira imeneyi. Kuphatikiza apo, palibe amene amachita manyazi poona kuti mankhwalawo atha kukhala ndi zotsatirapo zoopsa monga kukomoka. Pazinthu zanga zoyambira kugwiritsa ntchito (ndikumwa chithandizo masiku 4). Mapiritsiwo ndi osavuta kumeza, ndi akulu, muyenera kumwa madzi owonjezera, palinso kukoma kosasangalatsa. Zotsatira zoyipa sizinachitikebe, ndikukhulupirira, ndipo sizidzakhalako. Zotsatira zake, pakadali pano ndangoona kuchepa kwa chikhumbo. Ndidakondwera ndi mtengo wake. "

Kodi Glucophage amathandiziradi kuchepa thupi? Wopatsa thanzi amayankha:

Glucophage ndi mankhwala osokoneza bongo a hypoglycemic omwe amaperekedwa kwa matenda amitundu iwiri. Amagwiritsidwanso ntchito ngati kunenepa kwambiri kuti muchepetse kunenepa. Sikoyenera kugwiritsa ntchito mankhwalawa nokha, izi zimatha kuyambitsa zotsatirapo zoyipa.

Kuphatikizika ndi zisonyezo zakugwiritsira ntchito mankhwala a glucophage ndi mtengo wake

Kunenepa kwambiri ndi vuto lomwe likufunika kuthana ndi mavuto kuti athane ndi mavuto azaumoyo ndipo silikhudzanso atsikana okha omwe amafuna kuchepetsa thupi, komanso odwala matenda ashuga.

Mapiritsi a Glucophage (500, 850, 1000) kapena Glucophage kutalika (500, 750) amatha kuthana ndi mavutowa, popeza amalimbitsa shuga, amamugulitsa m'masitolo pamitengo yotsika mtengo ndipo ambiri amangowunika zabwino za mankhwalawa.

Kuphatikiza apo, mankhwalawa amangogwira kuchuluka kwa glucose kwambiri (hyperglycemia) ndipo samachepetsa pazomwe zili bwino, zomwe zingakhale zothandiza kwa onse matenda a shuga mellitus (DM) komanso kungowotcha mapaundi owonjezera.

Ndemanga pa kugwiritsa ntchito mankhwalawa

Pankhani yogwiritsa ntchito Glucofage pa intaneti, palinso ndemanga zambiri ndipo poyambira ndibwino kuyamba ndi miyala momwe mulingo wa metformin uli 500 (katatu patsiku) kapena 850 (kawiri pa tsiku). Amalangizidwa kuti azimwa chakudya chisanafike kapena atangomaliza kudya.

Pakatha sabata, endocrinologist amayang'ana momwe mankhwalawo amathandizira komanso ngati palibe zotsatira zake, mudzasinthana ndi metformin 1000, ndipo ngati ndende inali 500, ndiye kuti dokotala adzalembera 850.

Nthawi yomweyo, odwala omwe amawonjezera kukhathamira kwa mankhwalawa amalankhula za nseru zomwe zidasowa pambuyo pa masabata 1-2.

Anthu ambiri akamalandira mankhwalawa patsiku amayenera kukhala 1000 mpaka 2000 mg, koma osapitirira 3000 mg, chifukwa pakhala pali milandu yambiri ya bongo. Pazifukwa izi, dokotala nthawi zambiri amalemba mankhwala mapiritsi a 850 katatu patsiku kapena chikwi chimodzi, koma kawiri, chifukwa cha zovuta za matendawa.

Ndikofunikira kudziwa malingaliro a anthu pazomwe angagwiritse ntchito, chifukwa mutha kuphatikiza insulini ndi Glucofage 1000 kapena 850 ndipo ndikokwanira kumwa piritsi limodzi kamodzi patsiku. Kuphatikiza apo, anthu omwe ali ndi matenda ashuga salangiza kukweza kapena kusiya mankhwala paiwo, chifukwa izi zingakhudze shuga.

Makolo a ana omwe adapezeka ndi matenda amtundu woyamba nawonso anena malingaliro awo. Malinga ndi mawu awo, ngati vutoli limakhudza mwana, ndiye kuti dokotala amatha kumuuza mlingo wokhawokha wa 1000 mg, koma pokhapokha pazochitika komanso pambuyo pa zaka 10, chifukwa palibe zotsatira zonse zofufuza.

Glucofage ndi mizimu

Anthu ambiri akhala ndi chidwi ndi funso ngati Glucophage (500, 850 ndi 1000) kapena Glucophage kutalika (500, 750) amagwirizana ndi mowa kapena ngati mowa uyenera kusiyidwa kwathunthu.

Pazonse, iwo omwe amafuna kuti ataye mapaundi owonjezera kapena odwala matenda ashuga sakanatha kuganiza za ntchito yotere, chifukwa zinali zokwanira kuwerenga malangizo oti agwiritse ntchito.

Amati Glucophage ndi mowa siziphatikizana ndipo sizingagwiritsidwe ntchito palimodzi.

Mowa womwe umatengedwa posachedwa kapena mutamwa piritsi la Glucofage umakhudza kwambiri chiwindi ndipo anthu omwe ali ndi matenda a chiwindi amalemba zambiri za izi.. Kuphatikiza apo, panali milandu yokhudza kukonzekera kwa lactic acidosis (lactic acid chikomokere) ndipo pamankhwala ake kunali kofunikira kufunsa dokotala nthawi yomweyo.

Matendawa amadziwika ndi kutulutsidwa kwakukulu kwa lactic acid, chifukwa zomwe zimakhala zake zimaphatikizidwa ndipo matendawa amakula kwambiri. Kuphatikiza apo, madokotala amachenjeza kuti lactic acidosis ikhoza kufa ngati chithandizo sichikonzedwa mwachangu.

Choyipa chachikulu pamenepa ndichakuti simungathe kusankha njira yochiritsira pomwe munthu waledzera.

Ndikofunika kudziwa kuti mowa, kuphatikiza mowa, sugwirizana osati ndi Glucophage, komanso matenda a shuga, kotero ngati simukufuna kupeza zotsatira zosakonzeka, ndikulimbikitsidwa kuti musagwiritse ntchito limodzi. Anthu omwe amakonda kumwa amalangizidwa kuti asayambe kumwa mowa mkati mwa masiku atatu atamaliza maphunziro.

Ndemanga zazitali za Glucophage

Mankhwala omwe ali ndi nthawi yayitali Glucofage amakhala ndi zofananira komanso ma contraindication monga mtundu wake wokhazikika, koma ayenera kugwiritsidwa ntchito pafupipafupi.

Phindu ili silinkayamikiridwa kokha ndi odwala omwe ali ndi matenda amtundu wa 2, komanso anthu omwe amakonda kuiwala kumwa mankhwala.

Mankhwalawa amapezeka mu Mlingo wa 500 ndi 750 ndipo, motero, ali ndi mtengo wokwera kwambiri chifukwa chakuti zotsatira zake zimakhala motalikirapo.

Ogwiritsa ntchito apanga mndandanda wazikhalidwe zapadera za Glucophage yayitali:

• Ndikokwanira kumwa mankhwalawa kamodzi patsiku chakudya chamadzulo,
• Metformin ku Glucofage imakhala ndi nthawi yayitali ngati momwe zimakhalira nthawi zonse, koma imagwira ntchito motalika,
• Kumwa mankhwalawa sikungayambitse zotsatira zoyipa, makamaka m'mimba ndi ziwalo zam'mimba.

Akatswiri pakuwunika kwawo saiwala kukumbutsa anthu wamba za malangizo ogwiritsira ntchito, chifukwa ndikofunikira kudziwa kuti kuchuluka kwa mankhwala patsiku sikuyenera kupitirira 2000 mg.

Kuphatikiza apo, ngati gawo limodzi la Glucofage Long silikwanira tsiku lonse, ndiye kuti ndi zolondola kumwa mankhwalawa 2 pa tsiku, chifukwa ndikofunikira kuti mankhwalawa akwaniritse ntchito yake popanda kusokoneza.

Mtengo wamankhwala malinga ndi kuwunika kwa ogwiritsa ntchito

Anthu ambiri omwe adagula chida champhamvu chotentha mapaundi owonjezera ndikuwongolera shuga adazindikira kupezeka kwake muzipatala zonse komanso pamtengo wokwanira. Mtengo wapakati wa glucophage umatengera mlingo wa metformin ndipo ndi:

• 500 - 115-145 ma ruble.,
• 850 - 150-200 rubles.,
• 1000 - 200-250 rub.

Glucophage yayitali mumafakitale ndiokwera mtengo kwambiri, koma muyenera kuitenga pang'ono:

Ndikofunika kudziwa kuti mtengo womwe unanenedwa wa mankhwalawa umaphatikizanso mapiritsi 30 ndipo mitengo yonse inatengedwa makamaka kuchokera ku ndemanga ya anthu omwe adagula Glucofage m'masitolo apamwamba a metropolitan.

Momwe mungachiritsire matenda a shuga ndikuchepetsa thupi ndi Glucofage

Glucophage ndi mankhwala omwe amalembedwa kuti awonjezere shuga komanso mtundu wa 2 shuga. Itha kuthandizanso ndi matenda a shuga a mtundu woyamba, koma si mankhwala akuluakulu a mankhwalawo. Glucophage imatha ndipo iyenera kutengedwa mosadukiza, osapumira pakati pa maphunziro. Odwala ena amagwiritsa ntchito mankhwalawa kuti achepetse zizindikiro zaukalamba.

Zomwe zimagwiritsa ntchito mankhwalawa ndi Metformin (hydrochloride). Ichi ndiye maziko a mankhwala ambiri a 2 ashuga. Othandizira:

• Cellulose
• Magnesium wakuba,
• Hypromellose,
• Carlone sodium.

Mndandanda weniweni wa omwe amadzimva amasiyana kutengera mtundu wa mankhwalawo amasulidwe. Pali mankhwala ocheperako komanso mtundu wake wautali - Glucophage Long.

Metformin ndi chinthu chosagwirizana. Chifukwa cha kupezeka kwake, mankhwalawa amayamba kugwiritsidwa ntchito pang'onopang'ono kuti muchepetse zovuta zomwe zimachitika.

Zochita zamankhwala

Mankhwalawa amatithandizanso kukhala ndi anthu omwe ali ndi shuga wambiri. Chimakupatsani mwayi wolepheretsa kuyamwa kwa chakudya chamagulu nthawi yotsekemera chakudya, zomwe zimathandizanso kuti shuga akhale ndi matenda.

Mankhwalawa amagwira thupi pang'onopang'ono, osapangitsa kuti magazi achepe. Chifukwa chogwiritsa ntchito mankhwalawa nthawi zonse, kupanga shuga mu chiwindi kumachepetsedwa, index ya insulin imakhazikika.

Pakapita kanthawi mankhwala atayamba, zizindikirazi zimaleka kugwa msanga ngati mankhwala atangoyamba kumene.

Zotsatira zoyipa za mankhwalawa ndi kuchepa thupi. Zimathandizira kuwotcha kwamafuta, chifukwa zimachotsa insulin yochulukirapo, zomwe zimayambitsa kudziunjikira kwa lipids. Minofu imayamba kukonda insulini, yomwe imakuthandizani kuti muchepetse thupi.

Akatswiri ena amatsindika za kuthana ndi kukalamba kwa mankhwalawa. Zimalepheretsa mapangidwe a mafuta, omwe amayamba kudziunjikira nthawi yapakati, amasintha kayendedwe ka magazi, mkhalidwe wamagazi. Chifukwa cha izi, odwala okalamba amamva bwino komanso amawoneka ochepera.

Pakapita kanthawi mankhwala atayamba, wodwalayo ayenera kuyamba kumwa mankhwalawa, popeza kudya kwambiri zomwe zimagwira kumakupatsani mwayi wambiri wolimbana ndi shuga. Mlingo wapamwamba ndi 2550 mg wa Glucofage ndi 2000 mg wa Glucofage Long.

Mapiritsi a 500 mg amatengedwa kamodzi tsiku lililonse. Ndipo, pakapita masiku onse a 5-7, piritsi lina la 500-850 mg limawonjezera pa tsiku. Ngati mavuto ali ndi mphamvu kwambiri, katswiri angalangize kuwonjezera kuchuluka kwake pang'onopang'ono: theka la piritsi tsiku lililonse la 5-7.

Glucophage wa matenda ashuga amtundu woyamba

Glucophage sangathandize ndi mtundu woyamba wa shuga ngati agwiritsidwa ntchito ngati mankhwala akuluakulu. Kuti wodwalayo apitilize kuchita zinthu zina, ndikofunikira kubaya insulini. Mankhwalawa akhoza kuphatikizidwa ndi iwo, koma pali zinthu zina zomwe zimachitika mogwirizana.

Kugwiritsa ntchito insulin ndi glucophage kophatikizana kumatha kuyambitsa hypoglycemia. Kuti zisachitike, ndikofunikira kuchepetsa kuchuluka kwa Glucofage ndi jakisoni.

Ndikulimbikitsidwa kukaonana ndi dokotala za kuchuluka kwa mankhwalawa.

Akatswiri nthawi zambiri samapereka mankhwala othandizira insulin, popeza palimodzi ndi jakisoni amatha kutsegula hypoglycemia ndipo satha ntchito. Nthawi zambiri zotchulidwa mofananamo bwino.

Mukamachepetsa thupi

Nthawi zambiri, glucophage amagwiritsidwa ntchito ndi anthu omwe amafuna kuchepetsa thupi mosavuta komanso mopweteka.

Mankhwalawa amachepetsa shuga m'magazi, amalepheretsa mayamwidwe pang'ono, amathandizira kagayidwe ndipo amakulolani kutentha mafuta, omwe amaphatikizidwa chifukwa chosakwanira kumva insulini. Kuchepetsa thupi, mankhwalawa amatha kugwiritsidwa ntchito ndi onse odwala komanso odwala matenda ashuga.

Mlingo wa Glucofage umakhalabe chimodzimodzi ndi matenda ashuga. Popeza siikofunikira kuti muchepetse kwambiri shuga, tikulimbikitsidwa kuti mupereke mankhwalawa modekha, pang'onopang'ono kuposa matenda ashuga. Ngati anthu odwala matenda ashuga akulimbikitsidwa sabata iliyonse kuti awonjezere mlingo wa mankhwala ndi 500-850 mg patsiku, ndiye akamagwiritsa ntchito mafuta oyaka, tikulimbikitsidwa kuti muwonjezere mlingo uliwonse pakatha masiku 10 kapena 14.

Mankhwalawa amakulolani kuwotcha mafuta ochulukirapo ngakhale osachita zinthu zolimbitsa thupi komanso kutsatira zakudya zapadera. Komabe, ndikulimbikitsidwa kuti muzichita masewera olimbitsa thupi ndikutsatira zakudya zapadera kuti muwonjezere mphamvu ya pulogalamuyi.

Musanalembe kuchepa thupi, ndikofunikira kuti muziyang'ana ziwengo. Chifukwa chaichi, mlingo wochepa wa mankhwalawa umatengedwa. Muyenera kuwunikira momwe zinthu ziliri kwa maola 24.

Ngati zotupa sizikuwoneka, zovuta zina za matendawa sizinachitike, kutsekula m'mimba sikunayambike, mankhwalawa akhoza kupitilizidwa kugwiritsidwa ntchito.

Ndi zovuta zoyipa zomwe mumachita, mutha kuzikana mosavuta, popeza akatswiri azamankhwala amapereka ambiri mankhwalawa kuti achepetse thupi.