Angioflux - malangizo a boma ogwiritsira ntchito

Angioflux ndi angioprotector. Itha kuikidwa kokha ndi katswiri wazodziwitsa yemwe adazindikira kale, kutengera njira zakuzindikira.

Angioflux ndi angioprotector.

Kutulutsa mafomu ndi kapangidwe kake

Wodwala angagule mankhwalawa m'njira ziwiri zamasulidwe: yankho la kulowetsedwa ndi mtsempha wamkati ndi makapisozi amkamwa makonzedwe. Chosakaniza chophatikizacho ndi sulodexide. Monga zinthu zothandiza, lauryl sulfate ndi zinthu zina zimaphatikizidwa pakuphatikizidwa kwa sodium.

1 ml yankho lili ndi 300 LU (600 LU mu 2 ml) (lipoprotein lipase unit). Zoyikidwa mu ampoules. Pack of 10

Chigawo cha mankhwala omwe ali ndi 250 LU.

Zotsatira za pharmacological

Zomwe zimagwiritsidwa ntchito m'mankhwala ndizopangidwa mwachilengedwe. 80% ya kapangidwe kake ndi kachigawo kama heparin, 20% ndi dermatan sulfate. Mankhwala ali ndi antidrombotic ntchito ndi angioprotective kwenikweni. Chifukwa cha kugwiritsa ntchito mankhwalawa, kuchuluka kwa fibrinogen m'madzi a m'magazi kumachepetsedwa.

Chifukwa cha mankhwalawa, kukhulupirika kwa maselo a mtima kumatha kubwezeretsedwa. Mchitidwe wamagazi wamagazi umakhazikika.

Chosakaniza chophatikizacho ndi sulodexide.

Gulu la mankhwalawa lomwe wothandiziralo ndi mankhwala a antithrombotic.

Pharmacokinetics

Dongosolo la makolo limathandizira kulowetsa zinthu zomwe zimagwira mu gawo lalikulu la magazi. Kugawa kwamisonye ngakhale. Kuyamwa kwa yogwira pophika limapezeka m'matumbo aang'ono. Kusiyana kwa ma heparin osapindika ndikuti zomwe zimagwiritsidwa ntchito sizikuwonongeka. Izi zimabweretsa kuti mankhwalawa amachotsedwa mthupi la wodwalayo mwachangu.

Zizindikiro zogwiritsidwa ntchito

Mankhwalawa amalembera ma pathologies monga:

• shuga mellitus macroangiopathy,
• angiopathy, momwe chiopsezo cha thrombosis chikuwonjezeka,
• microangiopathy (retinopathy, neuropathy ndi nephropathy),
• odwala matenda ashuga phazi.

Mankhwalawa amalembera macroangiopathy omwe ali ndi matenda ashuga.
Ndi angiopathy, madokotala nthawi zambiri amapereka Angioflux.Nephropathy ndi chidziwitso pakugwiritsa ntchito mankhwalawa.

Contraindication

Mankhwalawa ali ndi zotsatira zoyipa komanso zotsutsana. Kuwonetsera kosafunikira kumatha kuchitika ngati wodwalayo atamwa mankhwalawo, ngakhale zina mwazovuta za thanzi lake komanso zotsutsana zomwe zilipo kale. Pokhapokha ngati izi, zosankha zoyipa zitha kukhala njira yowopsa.

Ngati wodwala ali ndi mavuto omwe alembedwa pansipa, sangathe kuthandizidwa ndi mankhwalawa:

• hemorrhagic diathesis ndi ma pathologies ena omwe hypocoagulation imalembedwa (kuchepa kwa magazi kuundana),
• kuchuluka kwa yogwira mankhwala.

Popeza sodium ilipo pakuphatikizika kwa mankhwalawa, sayenera kuperekedwa kwa iwo omwe amadya mchere wopanda mchere.

Mlingo ndi makonzedwe a Angioflux

Ndichizolowezi kuperekera mankhwalawa kudzera m'mitsempha komanso m'mitsempha, ngati atagwiritsidwa ntchito ngati yankho. Intravenous makonzedwe ikuchitika bolus kapena kukapanda kuleka (pogwiritsa ntchito dontho). Mlingo wofanana wa mankhwalawa komanso mtundu wa mankhwalawa ayenera kusankhidwa ndi adokotala okha, makamaka poganizira zamomwe akupangira, zotsatira za kufufuza ndi mawonekedwe a wodwala. Izi zikugwira ntchito pakukhazikitsa yankho ndi kuyendetsa makapisozi pakamwa.

Asanalandire chithandizo, wodwala aliyense ayenera kuphunzira malangizo kuti agwiritse ntchito.

Ndi hemorrhagic diathesis, kugwiritsa ntchito mankhwalawa ndizoletsedwa.

Pofuna kuyika dontho, muyenera kaye kuchepetsa mankhwalawa 0.9% sodium chloride - 150-200 mg.

Ndondomeko yovomerezeka yamankhwala imakhudza utsogoleri wa makolo kwa masiku 15-20. Pambuyo pake, wodwalayo amathandizidwa ndi makapisozi masiku 30-30.

Chithandizo chotere chimawonetsedwa kawiri pachaka. Mlingo ungasiyane kutengera momwe mkhalidwe wa wodwala umasinthira.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Mu trimester yoyamba, simungathe kupereka mankhwala. Mu trimesters yachiwiri ndi yachitatu, mutha kupereka mankhwala ngati njira yomaliza, ngati phindu lomwe mayi woyembekezera ali nalo lingakhale pachiwopsezo chotukuka kwa mwana wosabadwayo.

Pa nthawi yoyembekezera, kugwiritsa ntchito mankhwalawa ndikosayenera.

Kuchita ndi mankhwala ena

Mphamvu ya heparin ya heparin imalimbikitsidwa ndikumwa mankhwalawo. Zomwezi zimagwiranso ntchito kwa anticoagulant mankhwala osokoneza bongo ndi antiplatelet agents. Pachifukwa ichi, kugwiritsa ntchito mankhwalawa kuphatikiza kuyenera kupewedwa, chifukwa zimakhudza dongosolo la hemostatic. Kuchulukitsa kwa matenda a mtima kumatha kuchitika.

Ndemanga za Angioflux

N. N. Podgornaya, yemwe ndi dokotala wamkulu, Samara: “Nthawi zambiri ndimapereka mankhwala ngati jakisoni. Zotsatira zoyipa sizimachitika kawirikawiri, ndipo izi ndizokhutira chabe ndipo sizingasangalatse koma odwala. Ndikofunikira kuti nthawi yonse ya chithandizo chomwe wodwalayo akuyang'aniridwa ndi madotolo, chifukwa mankhwalawo amafunika kusintha ngati zikuwonekera. Ndipo nthawi zambiri iwo sanabwere. Chifukwa chake, ndimapeza mankhwalawa akugwira ntchito moyenera ndipo amayenda bwino mthupi. "

A. E. Nosova, katswiri wa zamtima, ku Moscow: “Mankhwalawa ndi abwino kwa macroangiopathy. Iyi ndi njira imodzi yothandiza kwambiri poyerekeza ndi ena. Tiyenera kumvetsetsa kuti popanda kuthandizidwa ndi dokotala, zotsatira zoyipa zaumoyo zimatha kupsa. Koma izi zikugwirizana kwambiri ndikumayambitsa yankho, m'malo motenga makapu. Amatha kutengedwera bwino kunyumba, zovuta zomwe zimawavuta sizivutitsa wodwala. Koma ngati matendawa ndi oopsa, nthawi zambiri amafunika kukhazikitsa yankho ndi chithandizo kuchipatala. Koma pali malamulo okhawo omwe amakhazikitsidwa. ”

Amamasulidwa ku pharmacies ndi mankhwala kuchokera kwa katswiri.

Mikhail, wazaka 58, ku Moscow: “Anandiliza kuchipatala. Dotolo adalankhula mwatsatanetsatane pazomwe ndimankhwala omwe amagwiritsidwa ntchito pochiritsa ndipo ndikukumbukira ndendende kuti mankhwalawa adatchulidwa. Ndinali wokondwa kuti lidafotokozedwa mwatsatanetsatane njira zamankhwala zomwe zimagwiritsidwa ntchito komanso chifukwa chake ndizofunikira. Izi zidandipangitsa kumva kuti ndine wotetezeka. Munthawi yonse ya zamankhwala, njira zofufuzira zimachitika, zinali zofunika kuchita mayeso kuti ndidziwe momwe zinthu zikusinthira komanso ngati pali mphamvu zina. Chidacho chimathandiza thupi, ndimaipereka kwa aliyense. ”

Polina, wazaka 24, Irkutsk: “Ndinkatenga makapisozi okhala ndi dzina lopatsidwa. Matenda ochititsa chidwi anali matenda a shuga. Ndinkada nkhawa ndi vuto langali, chifukwa ma pathologies owopsa 2 adathandizidwa. Lingaliro lopita kuchipatala silinapangidwe ndi adotolo, ngakhale iye mwini adaganizapo za izi. Koma adakhulupirira lingaliro la adotolo, omwe adayambitsa matenda ndi kupereka mayeso. Kutalika kwa mankhwalawa kunali miyezi ingapo, koma osati mankhwala okhawo omwe amagwiritsidwa ntchito, komanso mankhwala ena. Zotsatira zake zidakondweretsa, ndikulimbikitsa. Mtengo ndi wotsika. "

2. Kuchulukitsa komanso kuyenera

ANGIOFLUX 600 LU * / 2 ml, yankho la mtsempha wa magazi ndi mtsempha.
Mphemvu imodzi imakhala ndi: yogwira ntchito - sulodexide 600 LU, ANGIOFLUX 250 LU, makapisozi ofewa.
Mmodzi kapisozi muli: yogwira - sulodexide 250 LU, zotuluka: onani ndime 6.1. * - lipoprotein lipase mayunitsi.

4.2. Mlingo ndi makonzedwe.

Mothandizidwa (bolus kapena drip) kapena mu mnofu: 2 ml (1 ampoule) patsiku. Kwa mtsempha wa intravenous, mankhwalawa amathandizira kale mu 150-200 ml ya 0,9% sodium kolorayidi.
Pakamlomo: makapisozi awiri katatu patsiku pakati pa chakudya.
Chithandizo tikulimbikitsidwa kuti muthane ndi makolo kupaka mankhwalawa kwa masiku 15 mpaka 20, atatha kutenga makapisozi kwa masiku 30 mpaka 40. Njira yonse ya mankhwala imachitika 2 pachaka.
Kutalika kwa maphunziridwe ake ndi kumwa kwa mankhwalawa zimatha kusiyanasiyana malinga ndi zotsatira za kuchipatala.

5.1. Mankhwala

Angioflux ali ndi vasoprotective, antithrombotic, profibrinolytic, anticoagulant, lipid-kuchepetsa.
Kupanga kwa antithrombotic kanthu kumalumikizidwa ndi kuponderezana kwa factor Xa ndi IIa. Mphamvu ya profibrinolytic ya mankhwalawa imatheka chifukwa chokhoza kuwonjezera kuchuluka kwa minofu ya plasminogen activator (TAP) m'magazi ndikuchepetsa zomwe zimakhala ndi plasminogen activator inhibitor (ITAP) m'magazi.
Limagwirira vasoprotective kanthu limagwirizana ndi kubwezeretsa kapangidwe ndi magwiridwe mtima a maselo endothelial maselo, kubwezeretsa kwachilendo mphamvu osagwirizana magetsi pores wa zotumphukira chapansi.
Mankhwalawa amatithandizanso kukhathamiritsa kwamagazi m'magazi pochepetsa kuchuluka kwa triglycerides, chifukwa amathandizira lipolytic enzyme lipoprotein lipase, hydrolyzing triglycerides.
Mphamvu ya angioflux mu diabetesic nephropathy imatsimikizika ndi mphamvu yake yochepetsetsa makulidwe apansi ndi kupanga matrix a extracellular pochepetsa kuchuluka kwa maseloum mesangium.

6.3. Kutulutsa Fomu

Njira yothetsera kulowetsedwa kudzera m'mitsempha ndi mafupa, 600 LU / 2ml.
2 ml magalasi akuda am'maso ndi mphete yopumira.
Ma ampoules asanu mumatumba. Matuza awiri okhala ndi malangizo ogwiritsira ntchito amaikidwa pakatoni.
Makapisozi, 250 LE.
25 ma kapisozi m'matumba a chithuza. Matuza awiri okhala ndi malangizo ogwiritsira ntchito amaikidwa pakatoni.