Momwe insulin imakhudzira kunenepa kwambiri

Madzi a insulin amatulutsa kapamba poyankha pachakudya. Zimathandizira thupi kugwiritsa ntchito mphamvu kuchokera kuzakudya powongolera michere m'maselo. Mitsempha yakam'mimba ikaphwanya chakudya chamagulugigisi ku glucose, insulin imatsogolera glucose kumalo osungira - minofu glycogen, glycogen m'chiwindi ndi minofu ya adipose.

Vomerezani, zingakhale bwino ngati minofu yathu imadya michere, koma insulini sasamala komwe ingawatsogolere. Anthu ocheperako amatha kupindula ndi izi - kuti apangitse mapangidwe ake ataphunzitsidwa kuti apange minofu, koma anthu onenepa kwambiri ayenera kuthera nthawi yayitali kuti akhalebe osasinthasintha.

Ntchito za insulin m'thupi

Osawopa insulini, chifukwa kuwonjezera pa ntchito zake za anabolic (kupanga minofu ndi mafupa am'magazi), imalepheretsa kuwonongeka kwa mapuloteni am'mimba, imathandizira kapangidwe ka glycogen, ndikutsimikizira kuperekera kwa amino acid ku minofu. Ntchito yake yayikulu ndikusunga shuga wabwino m'magazi.

Mavuto amayamba pamene chidwi cha insulin chikuchepa. Mwachitsanzo, munthu amadya maswiti komanso kunenepa. Samatenga mafuta chifukwa cha insulini, koma chifukwa cha kuchuluka kwa zopatsa mphamvu, koma m'thupi mwake insulin imakhala yolimba kwambiri - amapitilira shuga m'magazi, kuyesera kuti itsike pang'ono. Kunenepa kwambiri pakokha kumapangitsa kulemera kwa thupi ndikusintha kapangidwe kazinthu ka m'magazi, koma kuchuluka kwa insulini kumapangitsa kuti kapamba azitha kuzimitsa khungu. Umu ndi momwe mtundu wachiwiri wa shuga umakhalira. Inde, izi sizichitika sabata limodzi kapena awiri, koma ngati mukunenepa kwambiri komanso ngati mumagwiritsa ntchito maswiti, muli pachiwopsezo.

Kuchulukitsa kwa insulin kotchinga kumalepheretsa kuwonongeka kwa malo ogulitsa mafuta mkati. Ngakhale ilipo yambiri - simudzachepa. Amachepetsa kugwiritsa ntchito mafuta ngati gwero lamphamvu, kupatutsa thupi kuma chakudya. Kodi izi zikugwirizana bwanji ndi zakudya? Tiyeni tiwone.

Milingo ya insulin ndi zakudya

Thupi limatulutsa insulini poyankha chakudya. Pali malingaliro atatu omwe amathandizira kuwongolera mulingo wake - iyi ndi glycemic index (GI), glycemic mzigo (GN) ndi insulin index (AI).

Mlozera wa glycemic umatsimikizira momwe shuga yanu yamagazi imakhalira mutatha kudya chakudya chamafuta. Mkulu akachuluka m'ndendemo, shuga amawonjezeka mofulumira ndipo thupi limatulutsa kwambiri insulin. Zakudya zokhala ndi GI yotsika ndizodziwika ndi mawonekedwe apamwamba amtundu (mbewu zonse, amadyera ndi masamba osakhazikika), ndipo zinthu zomwe zimakhala ndi GI yayitali zimadziwika ndi zoperewera zama fiber (mapira osenda, mbatata, maswiti). Chifukwa chake, mu mpunga oyera, GI ndi 90, ndipo yofiirira - 45. Panthawi yamatenda othandizira, CHIKWANGWANI chamafuta chimawonongeka, chomwe chimakulitsa GI ya malonda. Mwachitsanzo, GI ya karoti yaiwisi ndi 35, ndipo yophika - 85.

Katundu wa glycemic amakupatsani mwayi wodziwa momwe gawo linalake lazakudya zopatsa mphamvu zimakhudzira thupi. Asayansi aku Harvard adapeza kuti kuchuluka kwa chakudya chamagulu, kumakhala kokwanira kuchuluka kwa insulini. Chifukwa chake, mukakonza chakudya, muyenera kuwongolera magawo.

Kuti muwerenge katundu, njira iyi imagwiritsidwa ntchito:

(Zogulitsa GI / 100) x zamafuta azakudya pamakonzedwe.

GN Yotsika - mpaka 11, sing'anga - kuchokera 11 mpaka 19, okwera - kuchokera 20.

Mwachitsanzo, muyezo wa oatmeal 50 g umakhala ndi 32,7 chakudya. GI oatmeal ndi 40.

(40/100) x 32.7 = 13.08 - pafupifupi GN.

Momwemonso, timawerengera gawo la ayisikilimu wazirimu 65 g. Mndandanda wa glycemic wa ayisikilimu 60, gawo 65 g, zakudya pa ntchito 13.5.

(60/100) x 13.5 = 8.1 - GN yotsika.

Ndipo ngati pakuwerengera tikatenga magawo awiri a 130 g, ndiye kuti timapeza 17.5 - pafupi ndi GN yapamwamba.

Mndandanda wa insulin ukuwonetsa momwe timadzi timeneti timadzuka poyankha kudya zakudya zama protein. AI yapamwamba kwambiri ya mazira, tchizi, ng'ombe, nsomba, ndi nyemba. Koma mukukumbukira kuti timadzi timtunduwu timakhudzidwa ndi kayendedwe kazinthu zamagalimoto komanso kayendedwe ka amino acid. Chifukwa chake, izi ziyenera kukumbukiridwa ndi anthu omwe ali ndi matenda ashuga. Kwa ena onse, ndizosafunika kwenikweni.

Kodi tinganene chiyani pamenepa?

Zogulitsa zomwe zili ndi index yotsika ya glycemic sizingochepetsa kuteteza insulini, komanso zimapereka malingaliro osakhalitsa chifukwa chokhutira chifukwa cha kuchuluka kwa fiber. Zakudya zotere ziyenera kukhala maziko azakudya zochepetsa thupi.

Kuyeretsa ulusi ndi chithandizo cha kutentha kumachulukitsa chakudya GI pamene fiber mu chakudya komanso kukhalapo kwamafuta kumachepetsa kuyamwa kwa zakudya. Kuchepetsa pang'ono, kumachepetsa kuchuluka kwa shuga m'magazi komanso kuchepera kwa insulini. Yesani kudya mapuloteni ndi chakudya chamagulu limodzi, osapewa masamba ndipo musawope mafuta.

Ndikofunikira kuyendetsa magawo. Kuchuluka kwake, kumakhala kofunika kwambiri chifukwa cha kapamba komanso insulin kwambiri. Pankhaniyi, zakudya zazing'ono zingathandize. Kudya pang'ono, mudzapewa kuchuluka kwa glycemic komanso kuphulika kwa mahomoni.

Chakudya chochulukirapo chimabweretsa kunenepa kwambiri, ndipo kunenepa kwambiri nthawi zambiri kumayambitsa matenda ashuga. Muyenera kupanga zoperewera zama calorie m'zakudya zanu, musamadye zakudya zanu komanso muziwongolera kuchuluka kwa chakudya chamagulu omaliramo. Anthu omwe ali ndi vuto losakwanira la insulin ayenera kudya michere yambiri, koma mapuloteni ochulukirapo ndi mafuta monga gawo la zomwe amapeza kolori.

Mutha kudziwa kukhudzika kwanu motsimikiza. Ngati gawo lalikulu la chakudya likuyenda bwino komanso kumva kuti muli ndi mphamvu, ndiye kuti thupi lanu limatulutsa insulini. Ngati mukumva kutopa komanso kumva njala pambuyo pa ola limodzi, ndiye kuti chinsinsi chanu chikuwonjezeka - muyenera kulabadira kwambiri zomwe mumadya.

Kuperewera kwa kalori, zakudya zopanda pake, kusankha zakudya zamagetsi ochepa, kuwongolera magawo ndi chakudya kumathandizira kukhala ndi insulin yolimba komanso kuchepetsa thupi mwachangu. Komabe, ngati pali kukayikira kulikonse kwa matenda ashuga, muyenera kufunsa dokotala.

Kodi tikudziwa chiyani za insulin

M'mawu asayansi okhwima, insulin imatchulidwa ngati mahomoni a peptide (protein). Amapangidwa ndi kapamba kuti thupi lizitha kuwongolera shuga (makamaka, glucose) m'madzi a m'magazi. Ichi ndiye chowerengera kwambiri pamahomoni onse, ngakhale mpaka kumapeto kwake momwe zochita zake zimakhudzira minofu ndi maselo a thupi lonse sanaphunzire. Malingaliro ambiri omwe adalipo kale adasinthidwa mpaka pano; mikangano yokhudza udindo wake kudwala komanso kusowa kwa kulemera sikuchepera.

Ngati tirikunena za mphamvu yake, imagwira ntchito ngati gawo la glucose m'maselo: popanda insulini, glucose, zivute zitani m'magazi, sangadutse mu ma cell. Popanda glucose, maselo amakhala ndi njala, ndipo izi zimawonekera kwambiri mu shuga, pamene, motsutsana ndi maziko a kusowa kwa mahomoni, munthu amalemera kwambiri.

Kutengera izi, asayansi adaganiza kuti: ngati, kutengera zakusowa kwa insulini, anthu amachepetsa thupi, ndiye kuti ndizomveka kuganiza kuti kutengera zakumbuyo yake, mutha kuchira kwambiri

Insulin ndi mahomoni anzeru, kuphatikiza kwake kumawonjezeka molingana ndi kuchuluka kwa shuga m'magazi. Ndipo mwakutero, sizimalola kuti shuga azikundana ndi madzi am'madzi, nthawi yomweyo kutumiza shuga m'maselo. Kuphatikiza apo, adzachita izi ngakhale nthawi yomwe maselo sakhala ndi njala.Kenako glucose wambiri amayamba kudzikundikira m'mitsempha, ndikusintha kukhala glycogen ya chiwindi ndi minofu (mawonekedwe amtundu wa glucose, womwe umakhala mafuta ochulukitsa ngati mukumva njala), glycogen imatha pafupifupi maola 24. Pamene "masitolo" a glycogen adzaza mphamvu, zomwe zili mkati zimayambira m'mafuta.

Ngati pali insulini yambiri

Mu thupi lathanzi, zonse ndizolondola, insulini imachotsedweratu chifukwa chofunikira mukamadya maswiti kudyetsa maselo onse amthupi ndi maswiti. Koma nthawi zina pamakhala mavuto pamene insulin yochuluka imapangidwa. Madokotala amatcha izi "hyperinsulinism." Kusinthasintha kwakuthwa kwa shuga m'magazi ndikupanga hypoglycemia (shuga wochepa kwambiri) ndizovuta zake. Nthawi yomweyo, odwala amamva kufooka ndi kugona, chidwi sichikhala mozama, kulibe ntchito. Potengera komwe magawo a shuga achepa, kuthamanga kwa magazi kumatha kudumphira kwambiri, kufalikira kwa magazi muubongo kumavutika, kumakhala ndi njala ndipo sikuyenda bwino. Anthu omwe ali ndi glucose wotsika kwambiri amakhala osakwiya komanso amtopola, amatha kukhala amanjenje.

Ngati insulini imakwezedwa kwa nthawi yayitali, mtima wamatenda am'mimba umayamba kupita patsogolo, ndipo mawonekedwe a "mafuta" pamitsempha. Khungu limakhala lamafuta, ziphuphu zimachitika pafupipafupi, zimakhala zonenepa pamutu, kenako kunenepa kwambiri zimapezekanso, zomwe zimayambitsa kunenepa kwambiri, ngati njira sizinatenge nthawi. Pamakhala ngozi yowopsa mthupi - insulin kukana, komwe ma cell amakhala "ogontha" kuma signulin a insulin. Kenako chimbudzi chimapanga insulin yochulukirapo, yomwe imawonjezera kulemera.

Kodi kunenepa kwambiri kumachokera kuti?

Asayansi amakhulupirira kuti insulin yowonjezera komanso kulemera kwambiri ndizokhudzana. Hormone yowonjezera imabweretsa kuti glucose, yomwe ili m'madzi a m'magazi, imakankhidwa ndi insulin m'maselo mwa mphamvu, ndipo mphamvu zowonjezera zomwe zimapangidwa ndikuwonjezera shuga, maselo amasinthidwa kukhala mafuta. Mafuta ochulukirapo awa amawonjezeredwa ku adipocytes (ili ndi dzina lasayansi lama cell mafuta pansi pa khungu ndi ziwalo zamkati). Selo iliyonse yamafuta kumaso amadzaza ndi mafuta, ndipo imatha kutambasula mpaka kakhumi kapena kupitilira apo.

Choyambitsa chachikulu pamkhalidwewu chimawonedwa kuti ndizochulukirapo zamafuta m'zakudya ndi kukonda maswiti. Ngati mukuganiza kulinganiza kulemera ndi kuchuluka kwa insulin, zikuwoneka motere:

Kudya maswiti ndi zakudya zamakina -> thupi limatulutsa zambiri za insulin -> insulin imayendetsa maswiti m'maselo a thupi, pomwe mashupi amasintha kukhala mafuta -> mafuta ochulukirapo amadzaza m'maselo amafuta akadzaza, maselo atsopano amafuta amapangika -> kulemera kwakukulu kumafika kumbali, kumbuyo, nkhope ndi madera ena ovuta

Ngati mumatsatira mfundo, kuchepetsa kudya zakudya zosavuta zamafuta (shuga ndi maswiti), kuchepetsa kuchuluka kwa zopatsa mphamvu zamagulu m'zakudya kumachepetsa insulin ndi kaphatikizidwe wamafuta, zomwe zimathandiza kuti pakhale mgwirizano. Koma ndikofunikira kutsindika kuti zakudya zamafuta zimafunika kuchepetsedwa, koma osasiyidwa kwathunthu!

Kwa iwo omwe akuchira kuchokera ku insulin yochulukirapo, momwe chithandizo chimakhalira ndi zakudya zotsika kwambiri zamatumbo ndi masewera! Ndi zochitika zolimbitsa thupi zomwe zimatentha shuga wambiri ndikuletsa mafuta kuti asapangidwe.

Kafukufuku wokhudza gawo la insulin pakukula kwa thupi akupitilizabe, koma chenicheni chakuti vutoli lidakhudzidwa ndi kuperewera kwa zakudya bwino tsopano.

Mfundo Zofunika Kudziwa

Ambiri atha kukhala ndi lingaliro loti kugwiritsa ntchito zakudya zamagulu aliwonse kumawopseza kukhala onenepa kwambiri komanso wodwala kwambiri. Koma izi sizowona konse. Ngati uyu ndi munthu wathanzi yemwe amadya moyenera, ndipo samakonda kutafuna maswiti ndi maswiti, kuchuluka kwa insulini kumadzuka nthawi yoyamba kudya (kadzutsa, chakudya chamadzulo kapena chamasana), ndipo osakhalitsa. Izi ndizofunikira kuti pakhale shuga, insulini idyetsa maselo ndipo nthawi yomweyo amachotsedwa.

Potengera maziko a kuchuluka kwa insulini, mafuta amayambira kutikika, koma izi zimatha pafupifupi theka la ola, ndiye kuti mafuta amthupi amayamba kuchepa.Pakati pa chakudya, mafutawa amathyoledwa mthupi lanu, ndipo kulemera sikubwera. Ngati mungasunthire pakati pa chakudya, mafuta amatha kudya kwambiri. M'malo mwake, iyi ndi mfundo - kugwiritsa ntchito zopatsa mphamvu zambiri kuposa kungomaliza!

Ngati mumakonda kuluma ma cookie, idyani, imwani zinazake zokoma, kuchuluka kwa insulini kudzakulitsidwa, kenako kulemera kumayamba kufika

Ndikofunikanso kudziwa kuti sikuti insulini yokha yomwe imayambitsa mafuta. Kulemera kwambiri kumakhala kotheka ngakhale ndi gawo lotsika la mahomoni awa, ngati chakudya chimakhala chambiri m'mafuta. Chifukwa chake, ndikofunikira kuti chakudyacho sichinali chakudya chokha, komanso mafuta pang'ono.

Amakhulupiriranso kuti insulin yowonjezera imasowetsa chakudya, komanso iyi ndi malo osangalatsa. Pakatikati pa njala yomwe ili muubongo imakhudza kuchuluka kwa shuga. Ngati sikokwanira, tikufuna kudya, ngati tili ochulukirapo, timakana chakudya. Ngati pali insulini yambiri, mwachidziwikire tidzafuna kudya, chifukwa imachepetsa kuchuluka kwa shuga m'magazi. Ndipo ichi ndichinthu chinanso chomwe kuti kunenepa kwambiri kungabwere. Chakudya chimakwanira maselo, koma ubongo ndi "wanjala"!

Mapuloteni ndi othandiza, koma modekha!

Tanena kuti chakudya chamafuta chimapangitsa kuti insulin iwonjezeke, koma sizinthu zokhazo zomwe zimapangitsa kuti timadzi tambiri timene timapanga. Mapuloteni azakudya amathandizanso kapamba kuti apange insulin, koma kuwonjezeka kwakeko sikumatenga nthawi yayitali. Kufanana ndi insulin, glucagon nthawi yomweyo imayamba kugwira ntchito - mahomoni otsutsana, omwe amapanga shuga popanda kupangidwa kwa mafuta. Chifukwa chake, zakudya zama protein ambiri sizipatsa phindu, ngati kudya mafuta ochulukirapo.

Ndani ayenera kuda nkhawa?

Mavuto olemera omwe amadza ndi insulin yowonjezera amatha makamaka kwa anthu omwe ali ndi matenda ashuga m'mabanja awo. Ayenera kupimidwa ndi dokotala pafupipafupi, kuyang'ana kuchuluka kwa shuga m'magazi, kuyang'anira kudya kwawo, kutsatsa maswiti komanso zakudya zamafuta. Kusokonezeka kwa kapamba kumadzetsa kusuta ndi kumwa mowa, chifukwa chake anthu omwe ali ndi zizolowezi zoyipa ayenera kuyang'anitsitsa zakudya zawo mosamalitsa.

Pangozi ndi odwala omwe ali ndi vuto la chikhodzodzo ndi chikhodzodzo, chifukwa ziwalozi zimalumikizana ndi kapamba. Ngati atupa, amapitilira kapamba, ndipo kenako ntchito yake pa insulin.

Iwo omwe alibe ndondomeko yodyetsa thanzi amakhalanso pachiwopsezo, akumangodya mothawathawa, akumva njala kwa nthawi yayitali, komanso akuvutika ndi mavitamini. Komanso azimayi omwe amamwa njira zakulera pakamwa (mapiritsi oteteza kulera) ali pachiwopsezo chachikulu.

Zotsatira za chakudya pamankhwala

Sikuti aliyense wodwala matenda ashuga amatha kudziwa zomwe zimachitika mthupi mwake pakudya mkate wamphesa wa tirigu wabwino kwambiri. Poganizira nkhaniyi, ziyenera kudziwika kuti buledi ndiwopatsa mphamvu ndi wowuma pazomwe zimapangidwira.

Itha kugayidwa mwachangu ndikusinthidwa kukhala glucose, yomwe imakhala shuga wamagazi ndipo imagawidwa kumitundu yonse ndi machitidwe.

Pakadali pano, thupi limakumana ndi gawo limodzi la magawo a hyperglycemia (mkhalidwe wamagazi pomwe shuga m'magazi ikukwera kwambiri mpaka milingo yayikulu, ndipo insulin sangathe kuthana nayo).

Ndikofunikira kudziwa padera kuti pakadali pano ziphuphu za munthu wathanzi zimakhudzana ndi glucose komanso mwachangu momwe zimakhalira zimatulutsa insulini m'magazi, yomwe imatha kugwira ntchito zake zingapo nthawi imodzi:

• Amapanga nkhokwe yamphamvu, komabe, nthawi imeneyi ndiyifupi kwambiri,
• kwambiri amachepetsa kuchuluka kwa shuga m'magazi, kukakamiza kuti isalowe ziwalo zonse, koma okhawo omwe akufunika kwambiri.

Mu shuga mellitus, njirazi zimachitika moyenera.

Zakudya zomanga thupi ndi mafuta

Kupanga mutu wa mkate, ndikofunikira kuganizira momwe amagwiritsidwira ntchito ndi batala monga chitsanzo cha chakudya chamafuta ndi mafuta.Monga taonera kale, mkate ndi chakudya chomwe chimapangidwa ndikukhala shuga. Mafuta ndi lipid. Mukakonza chimbudzi, chimadzakhala mafuta acid, omwe, monga shuga, amalowa m'magazi. Mlingo wa shuga wamunthu umachulukanso nthawi yomweyo, ndipo zikondamoyo zimayimitsa izi posachedwa ndikupanga insulin.

Ngati chiwalochi chili bwino, ndiye kuti insulini idzapangidwa ndendende momwe mungafunikire kuti muchepetse shuga yambiri. Kupanda kutero (ngati pali zovuta ndi kapamba ndipo matenda a shuga apezeka), insulini ya mahomoni siyipangidwa mokwanira kuposa momwe iyenera.

Zotsatira zake, gawo la mphamvu yamafuta omwe amachokera ku chakudya limasungidwa m malo osungirako, mwanjira ina, m'mafuta amafuta. M'magawo otsatira, njirayi idzakhala chifukwa chachikulu choti kulemera kwambiri kuonekere.

Ndi kansa yodwala komanso yofooka yomwe imalongosola kukula kwa kunenepa kwambiri kapena kungowonjezera vuto losafunikira la shuga. Ngati munthu ali ndi thanzi labwino, ndiye kuti njira yodwalitsa imeneyi siyabwino kwa iye, chifukwa chakudya chamafuta ndi mafuta zimatha kukonzedwa popanda kuchititsa kunenepa kwambiri.

Hyperinsulism ndi chizolowezi cha munthu wina kuyamba kunenepa kwambiri.

Kudya mafuta padera ndi zakudya zina

Kupitilizabe zitsanzo za chakudya, muyenera kuganizira zogwiritsa ntchito lipids zokha, mwachitsanzo, tchizi cholimba. Mafuta amodzi akalowa m'thupi, sangakhudze kuchuluka kwa shuga ndi insulin. Zikondazo zokha sizitulutsa timadzi tokwanira komanso njira yosinthira zinthu kukhala mphamvu zowonjezera siziyamba.

Ngakhale izi, palibe amene anganene mwanjira iliyonse kuti lipid yodyedwa singakhudze thupi. Izi zitha kufotokozedwa bwino ndikuti pakupanga chimbudzi, thupi limachotsa zinthu zonse zomwe zingatheke muzakudya zomwe zidawonongeka, mwachitsanzo:

1. mavitamini
2. kufufuza zinthu
3. mchere wamchere.

Chifukwa cha njirayi, zinthu zofunika zofunikira za metabolism zokwanira zimapezeka.

Zomwe takambiranazi sitinganene kuti ndizolondola, chifukwa zimakhala zosavuta komanso zowoneka bwino. Komabe, tanthauzo la njirayi limafotokozedwa mokwanira. Ngati mukumvetsetsa tanthauzo la izi, ndiye kuti mutha kusintha momwe mumadyera. Izi zipangitsa kuti kupewetsa kulemera kwakukulu mu mtundu 2 wa shuga. Zakudya zokwanira ndi shuga wambiri ndizofunikanso pano.

Pomaliza, ziyenera kudziwidwa kuti pankhani ya kulemera, ndiye kapamba yemwe amachita gawo lalikulu. Ngati munthu ali ndi thanzi labwino, ndiye kuti amatha kuthana ndi vuto lake ndipo sizimamupweteketsa, kwinaku akumakhalabe wathanzi.

Kupanda kutero, pali zovuta zazikulu ndikupanga kwa insulin ya mahomoni kapena ngakhale kusakwanira kwake. Zikondazo zimatha kupangitsa kuti mafuta achilengedwe omwe amapezeka muzosungidwa kumalo osungira. Zotsatira zake, kuwonda pang'onopang'ono kumayamba ndipo kunenepa kwambiri kumayamba.

Ngati wodwala matenda ashuga samayang'anira zomwe amadya ndipo amadya zakudya zokhala ndi shuga, izi zimatha kukhala zofunikira pakukula kwa kusowa kwa kapamba. Pamapeto pake, izi zitha kutsogolera ku mfundo yoti insulini sipangapangidwe mwaokha.

Muyenera kukhala ndi chidwi chowerenga za zomwe zinakuchititsani kuti muchepetse kulemera kwa mmodzi wa owerenga athu.

Zomwe zimapangitsa kuti pakhale insulin kukana

Zomwe zimayambitsa kukana insulini sizikudziwika. Amakhulupirira kuti zimatha kuyambitsa zovuta zomwe zimachitika m'magawo angapo: kuchokera pakusintha kwa molekyulu ya insulin komanso kusowa kwa insulin receptors kupita pamavuto a kufalikira kwa chizindikiro.

Asayansi ambiri amavomereza kuti chifukwa chachikulu chowonekera cha kukana insulini komanso matenda ashuga ndi kusowa kwa chizindikiro kuchokera ku molekyulu ya insulin kupita ku maselo a minyewa yomwe glucose yochokera m'magazi amayenera kulowa.

Matenda a shuga ndi kupsinjika kudzakhala chinthu chakale

Matenda a shuga ndi omwe amayambitsa pafupifupi 80% yonse yamikwingwirima ndi kuduladula. Anthu 7 mwa anthu 10 amafa chifukwa cha mitsempha ya mtima kapena ubongo. Pafupifupi nthawi zonse, chifukwa chomaliza chomaliza ndi chimodzimodzi - shuga wamwazi.

Shuga akhoza ndipo amayenera kugwetsedwa, apo ayi. Koma izi sizichiritsa matendawa, koma zimangothandiza kulimbana ndi kufufuza, osati zomwe zimayambitsa matendawa.

Mankhwala okhawo omwe amalimbikitsidwa mwalamulo kwa odwala matenda ashuga komanso ogwiritsidwa ntchito ndi endocrinologists pantchito yawo ndi Ji Dao shuga patch.

Kugwiritsa ntchito bwino kwa mankhwalawa, kuwerengera malinga ndi njira yokhazikika (kuchuluka kwa odwala omwe achiwonjezere kuchuluka kwa odwala omwe ali pagulu la anthu 100 omwe adachitiridwa chithandizo):

• Matenda a shuga - 95%
• Kuthetsa kwa mitsempha thrombosis - 70%
• Kuthetsa kwa kugunda kwamtima kwamphamvu - 90%
• Kuthana ndi kuthamanga kwa magazi - 92%
• Kuwonjezeka kwa mphamvu masana, kukonza kugona usiku - 97%

Opanga Ji Dao si bungwe lazamalonda ndipo amalipiridwa ndi boma. Chifukwa chake, tsopano wokhala aliyense ali ndi mwayi wopeza mankhwalawo kuchotsera 50%.

Izi zingachitike chifukwa chimodzi kapena zingapo:

1. Kunenepa kwambiri - Amaphatikizidwa ndi insulin kukana mu 75% ya milandu. Ziwerengero zikuwonetsa kuti kuwonjezeka kwa 40% kuchokera ku chizolowezi kumabweretsa kutsika komweko kwa kutsika kwa chidwi cha insulin. Chiwopsezo china cha kusowa kwa metabolic ndi kunenepa kwambiri kwam'mimba, i.e. pamimba. Chowonadi ndi chakuti minofu ya adipose, yomwe imapangidwa pakhoma lamkati lakumbuyo, imadziwika ndi zochita zapamwamba za metabolic, ndikuchokera kuti kuchuluka kwakukulu kwamafuta acid kumalowa m'magazi.
2. Mitundu - kufalitsa majini okonzeratu ku insulin kukana matenda a shuga ndi matenda a shuga. Ngati achibale apafupi amakhala ndi matenda ashuga, mwayi wokhala ndi zovuta za insulin sensitivity ndiwambiri kwambiri, makamaka ndi moyo womwe simungawutchule wathanzi. Amakhulupirira kuti kukana koyambirira kunapangidwira kuthandiza anthu. Munthawi yokhutitsidwa bwino, anthu amapulumutsa mafuta, mwa anjala - okhawo omwe anali ndi malo ochulukirapo, ndiye kuti, anthu omwe ali ndi insulin kukana, adapulumuka. Zakudya zambiri masiku ano zimabweretsa kunenepa kwambiri, matenda oopsa komanso matenda ashuga.
3. Kulephera kuchita masewera olimbitsa thupi - kumabweretsa chakuti minofu imafuna zakudya zochepa. Koma ndi minofu yam'mimba yomwe imadya 80% ya shuga kuchokera m'magazi. Ngati maselo am'mimba amafunikira mphamvu zambiri kuti athandizire ntchito zawo zofunika, amayamba kunyalanyaza insulin yomwe imanyamula shuga mwa iwo.
4. M'badwo - Pambuyo zaka 50, kuthekera kwa kukana insulini ndi matenda ashuga ndi 30% kuposa.
5. Chakudya chopatsa thanzi - kudya kwambiri zakudya zopatsa thanzi, kukonda shuga wowonjezera kumayambitsa shuga m'magazi, kupanga insulini mwachangu, chifukwa chake, kusafuna kwa maselo amthupi kuzizindikiritsa, zomwe zimayambitsa matenda a shuga.
6. Mankhwala - Mankhwala ena amatha kuyambitsa zovuta za insulin - corticosteroids (mankhwalawa rheumatism, mphumu, leukemia, hepatitis), beta-blockers (arrhythmia, myocardial infarction), thiazide diuretics (diuretics), vitamini B

Zizindikiro zake

Popanda kuyesa, ndizosatheka kudziwa kuti maselo amthupi adayamba kuwona bwino kwambiri insulini yomwe idalandiridwa m'magazi. Zizindikiro za kukana insulini zitha kupezeka chifukwa cha matenda ena, kugwira ntchito mopitirira muyeso, zotsatira za kuperewera kwa zakudya m'thupi:

• kulakalaka
• kuzindikira, kuvutika kukumbukira chidziwitso,
• kuchuluka kwa mpweya m'matumbo,
• ulesi ndi kugona tulo, makamaka pambuyo pambiri yodyera,
• kuchuluka kwa mafuta pamimba, mapangidwe a "lifebuoy",
• kukhumudwa, kukhumudwa,
• nthawi ndi nthawi mumatuluka magazi.

Kuphatikiza pazizindikirozi, dokotala amayesa chizindikiro cha kukana insulin asanapange matenda. Wodwala wodwala matendawa amatha kunenepa kwambiri, ali ndi makolo kapena abale ake omwe ali ndi matenda ashuga, azimayi amakhala ndi ovary ya polycystic kapena.

Chizindikiro chachikulu cha kupezeka kwa insulin kukokana ndi kuchuluka kwa m'mimba. Anthu onenepa kwambiri amawunika mtundu wa kunenepa kwambiri. Mtundu wa gynecoid (mafuta amadzaza pansi m'chiuno, kuchuluka kwakukulu m'chiuno ndi matako) ndikotetezeka, zovuta zama metabolic sizachilendo nawo. Mtundu wa Android (mafuta pamimba, mapewa, kumbuyo) umalumikizidwa ndi chiwopsezo chachikulu cha matenda ashuga.

Zolemba za kusokonekera kwa insulin kagayidwe kake ndi BMI ndi chiuno mwa chiuno (OT / V). Ndi BMI> 27, OT / OB> 1 mwaimuna ndi OT / AB> 0,8 mwa mkazi, ndizotheka kwambiri kuti wodwalayo ali ndi insulin kupinga syndrome.

Chizindikiro chachitatu, chomwe mwina ndi 90% chimaloleza kukhazikitsa kuphwanya - wakuda acanthosis. Awa ndi madera a khungu lokhala ndi pigmentation yowonjezereka, yomwe nthawi zambiri imakhala yolimba komanso yolimba. Zitha kukhala pamapewa ndi mawondo, kumbuyo kwa khosi, pansi pa chifuwa, pazolumikizana za zala, m'mphepete komanso m'miyendo.

Kuti atsimikizire matendawa, wodwala yemwe ali ndi zizindikiro ndi zolemba pamwambapa amayesedwa kuyesa kwa insulin, kutengera komwe matendawa adatsimikiza.

Kuyesa

Mu Laboratories, kusanthula komwe kumafunikira kuti kudziwa momwe maselo amafunira insulin nthawi zambiri kumatchedwa "Kuunika kwa Insulin Resistance."

Momwe mungaperekere magazi kuti mupeze zotsimikizika:

1. Mukalandira chithandizo kuchokera kwa dokotala yemwe wakupezekerani, kambiranani naye zamndandanda wazamankhwala, njira zakulera komanso mavitamini omwe atengedwa kuti asatenge omwe angakhudze magazi.
2. Tsiku loti lisanachitike, muyenera kuletsa maphunzirowo, yesetsani kupewa zovuta komanso zolimbitsa thupi, osamwa zakumwa zomwe zimakhala ndi mowa. Nthawi ya chakudya chamadzulo iyenera kuwerengedwa kuti isanatenge magazi Maola 8 mpaka 14 apita .
3. Yesetsani mayeso pamimba yopanda kanthu. Izi zikutanthauza kuti m'mawa ndizoletsedwa kutsuka mano, kutafuna chingamu chomwe mulibe shuga, kumwa zakumwa zilizonse, kuphatikizapo zosaphatikizidwa. Mutha kusuta kutatsala ola limodzi kuti ayendere labala .

Izi ndizofunikira pakukonzekera kuwunikiraku chifukwa chakuti kapu yoletsa khofi, itamwa nthawi yolakwika, imatha kusintha kwambiri zowonetsa shuga.

Pambuyo poti kusanthula kwafotokozedwa, ndalamayi yotsutsa insulini imawerengeredwa mu labotale potengera kuchuluka kwa shuga wamagazi ndi kuchuluka kwa insulini m'madzi a m'magazi.

• Dziwani zambiri: - bwanji kutenga malamulowo.

Mlozera wa insulin

Kuyambira kumapeto kwa zaka 70s zapitazo, kuyezetsa kwakukulu kwa hyperinsulinulin kunawonedwa ngati muyeso wa golide woyesa zochita za insulin. Ngakhale kuti zotsatira za kuwunikirako zinali zolondola kwambiri, kukhazikitsidwa kwake kunali kogwira ntchito kwambiri ndipo kunafunikira zida zabwino zaluso la labotale. Mu 1985, njira yosavuta idapangidwira, ndipo kudalirika kwa insulin kukana ndi data ya mayeso a clamp kudatsimikiziridwa. Njirayi imakhazikitsidwa pa mtundu wa masamu wa HOMA-IR (mtundu wa homeostatic) wodziwitsa kukana kwa insulin.

Mlozera wotsutsa wa insulini amawerengedwa malinga ndi njira yomwe idafunikira chidziwitso chochepa - basal (kusala) glucose yomwe ikuwonetsedwa mmol / l ndi insulin insulin mu μU / ml: HOMA-IR = shuga x insulin / 22.5.

Mlingo wa HOMA-IR, womwe umawonetsa kusowa kwa metabolic, umatsimikizika potengera zowerengera.Kafukufuku adatengedwa kuchokera pagulu lalikulu la anthu ndipo mndandanda wamawonekedwe amawerengedwa. Zomwe zidanenedwa ngati kuchuluka kwa magawo 75 a magawidwewo mwa anthuwa. Kwa magulu osiyanasiyana a anthu, zisonyezo zamkati ndizosiyana. Njira yodziwira insulin m'magazi imawakhudzanso.

Ma labotor ambiri amayika khomo kwa anthu azaka zapakati pa 20-60 zaka 2.7 zamisonkhano wamba. Izi zikutanthauza kuti kuwonjezeka kwa index ya kukhudzana ndi insulin pamwambapa 2.7 kukuwonetsa kuphwanyidwa kwa kumva kwa insulin ngati munthuyo sakudwala matenda ashuga.

Momwe insulin imayang'anira kagayidwe

Insulin m'thupi la munthu:

• imalimbikitsa kusamutsa shuga, amino acid, potaziyamu ndi magnesium mu minofu,
• kumawonjezera masitolo a glycogen mu minofu ndi chiwindi,
• amachepetsa mapangidwe a shuga m'magazi a chiwindi,
• zimathandizira kapangidwe ka mapuloteni ndikuchepetsa kutsika kwawo,
• imalimbikitsa mapangidwe wamafuta acid komanso kupewa kutsekeka kwamafuta.

Ntchito yayikulu ya insulini ya mahomoni m'thupi ndi kutulutsa shuga kuchokera m'magazi kupita kumaselo am'misempha ndi mafuta. Zoyambazo ndi zomwe zimapangitsa kupuma, kusuntha, kuthamanga kwa magazi, chakudya chomaliza chosunga zakudya. Kuti glucose alowe minofu, iyenera kudutsa nembanemba. Insulin imamuthandiza pamenepa, mophiphiritsa, amatsegula chipata cha khola.

Pa membrane wa khungu ndi puloteni yapadera, yopanga magawo awiri, yotchulidwa a ndi b. Imasewera gawo la receptor - zimathandiza kuzindikira insulin. Poyandikira membrane wa cell, molekyulu ya insulini imamangirira ku-subunit ya receptor, pambuyo pake imasintha malo ake molekyulu ya mapuloteni. Njirayi imayambitsa ntchito ya b-subunit, yomwe imayendetsa chizindikiro kuti iyambe kugwira ntchito kwa ma enzyme. Zomwezo, zimathandizira kuyenda kwa mapuloteni onyamula a GLUT-4, zimasunthira zimagwira ndi kuphatikiza nawo, zomwe zimapangitsa kuti glucose idutse kuchokera m'magazi kulowa mu cell.

Mwa anthu omwe ali ndi insulin kukana matenda komanso odwala ambiri omwe ali ndi matenda a shuga 2, izi zimayambira pachiyambi pomwe - ena mwa olandilira sazindikira insulin m'magazi.

Mimba ndi Insulin Resistance

Kukana kwa insulini kumabweretsa shuga wokwanira wamwazi, yemwe amapangitsa kuti ntchito ya pancreatic iwonjezeke, komanso matenda a shuga. Mlingo wa insulin m'magazi umachuluka, zomwe zimapangitsa kuti minofu ya adipose iwonjezeke. Mafuta ochulukirapo amachepetsa mphamvu ya insulin.

Chosangalatsa ndichakuti kukana insulini panthawi yovomerezeka ndizachilendo, kumakhala kwathupi lathupi. Izi zikufotokozedwa ndikuti glucose ndiye chakudya chachikulu cha mwana wakhanda m'mimba. Nthawi yayitali kwambiri, ndiye kuti pakufunika. Kuchokera lachitatu trimester ya glucose, mwana wosabadwayo amayamba kusowa, placenta imaphatikizidwa ndikuwongolera komwe ikuyenda. Imasunga mapuloteni a cytokine, omwe amapereka insulin kukana. Pambuyo pa kubala mwana, chilichonse chimabwerera kumalo ake ndipo zamphamvu za insulin zimabwezeretseka.

Mwa amayi omwe ali ndi zovuta zowonjezera thupi komanso zovuta zapakati, kukana insulini kumatha kupitirira kubereka, zomwe zimawonjezera chiwopsezo chawo cha matenda ashuga.

Doctor of Medical Science, Mutu wa Institute of Diabetesology - Tatyana Yakovleva

Ndakhala ndikuphunzira matenda a shuga kwa zaka zambiri. Zimakhala zowopsa anthu ambiri akamwalira, ndipo makamaka amakhala olumala chifukwa cha matenda ashuga.

Ndithamangira kunena mbiri yabwino - Endocrinological Research Center ya Russian Academy of Medical Sayansi yakwanitsa kupanga mankhwala omwe amachiritsa odwala matenda ashuga mellitus. Pakadali pano, kugwiritsa ntchito bwino kwa mankhwalawa kuyandikira 98%.

Nkhani ina yabwino: Unduna wa Zaumoyo wateteza kukhazikitsidwa kwa pulogalamu yapadera yomwe imalipira mtengo wapamwamba wa mankhwalawa. Ku Russia, odwala matenda ashuga mpaka Epulo 17 (kuphatikiza) nditha kuipeza - Kwa ma ruble 147 okha!

Zotsatira za kuchuluka kwa insulin

Insulin yayikulu pamunda wamankhwala imadziwika kuti hyperinsulinemia.Ndi iye yemwe amatsogolera kunenepa kwambiri, pakukula kwa minyewa ya mtima ndi mitsempha yamagazi, ndipo nthawi zina amapezeka ndi khansa. Kuchulukana kosasintha kwa mahomoni awa m'magazi kumapangitsa kuti maselo a thupi lathu athe kulimbana ndi mphamvu zake.

Mukakhazikika kukhazikika kotero, gland imayamba kupanga zochulukirapo za zinthuzi. Chifukwa chake, bwalo loipa lazakudya zoyipa mthupi limapangidwa, zomwe zimabweretsa zovuta zazikulu, kukulira kwakukulu. Ndiye, momwe mungapangire mofulumira komanso moyenera kuchepetsa kuchuluka kwa insulin kuti muchepetse kunenepa, mungakhale bwanji wathanzi?

Kuchepetsa insulini ndikuchotsa mapaundi owonjezera

Ngati munthu wonenepa kwambiri akulimbana ndi ma kilogalamu odedwa mwanjira iliyonse, ngati achita zonse zofunika kuti achepetse thupi, koma osakwanira, ayenera kulumikizana ndi akatswiri othandizira odwala ndikuwayeza mayeso kuti adziwe kuchuluka kwa insulin. Mwinanso mayeso amawonetsa kuti kuchuluka kwa mahomoniwo ndi okwera kwambiri.

Pakati pa malingaliro monga insulin ndi kuchepa thupi, ubale wolunjika wakhazikitsidwa. Ngati munthu adya zakudya zambiri tsiku lililonse, ndikupangitsa kuchuluka kwa shuga ndi insulin, ndiye kuti amapeza mapaundi owonjezera. Kuphatikiza apo, njira yowonjezerayo izikhala yachangu.

Munthu akamadya zakudya zoyipa kapena kumwa mahomoni opanga, kuchuluka kwa glucose konse komwe kumapangidwa ndimwazi kumangowonjezereka. Ngati munthu adya dongosolo la kuchuluka kwakukulu kuposa momwe amafunikira pamoyo komanso kuchuluka kwa zochita za tsiku ndi tsiku, maselowo amalandira shuga wambiri kuposa kuchuluka kwake. Izi, zikagwiritsidwa ntchito mosakwanira, zimayamba kudziunjikira mwachangu mthupi, m'mbuyomu zomwe zidasinthidwa kukhala mafuta.

Mawonekedwe a insulin yowonjezereka

Kukaniza mahomoni ndi kuchuluka kwake sikumayambitsa zizindikiro zilizonse zapadera, makamaka m'magawo oyambira a pathological. Anthu ambiri amakhala ndi insulin yokwanira pazaka zambiri ndipo nthawi zambiri samadziwa kuchuluka kwa shuga mpaka atayesedwa.

Zizindikiro zimayamba kuonekera mwa munthu ngati chitukuko cha matenda ashuga chikuyambira pazakulephera kwa insulin. Mwa zina zazikulu za matenda titha kuzindikira:

• Kumva ludzu kosalekeza

• Njala yayikulu yomwe singathe mukangodya,
• Kukodza pafupipafupi
• Kuwona kukhudza m'mapazi ndi manja
• Kupirira kutopa, komwe kumadziwonetsa kwakanthawi komanso nthawi zambiri kuposa masiku.

Nthawi zina, pamaso pa kukana insulin inayake mwa munthu, khungu limayamba kuwoneka pakhosi, komanso kumiyendo.

Ngati muli ndi zizindikiro zotere, muyenera kulankhulana ndi katswiri wodziwa bwino kuti mumupime komanso kuti mutsimikizire kuti ali ndi vutoli. Ngati magazi akuwonetsa kuchuluka kwa insulini, ngati palibe chitukuko cha mtundu wina wa matenda osokoneza bongo omwe amafunikira chithandizo chamankhwala chokha, ndikofunikira kuchitapo kanthu. Ndiye, mungatani kuti muchepetse kuchuluka kwa mahomoni anu mwazotheka kunyumba? Pali zosankha zambiri ndipo chilichonse chikuyenera kuganiziridwa mwatsatanetsatane.

Zizindikiro za insulin kukaniza ndi kuzindikira

Mutha kukayikiridwa kuti mumakhala ndi insulin ngati zizindikiro ndi / kapena mayesero anu akuwonetsa kuti muli nacho. Mulinso:

• kunenepa kwambiri m'chiuno (pamimba),
• kuyezetsa magazi koyipa kwa cholesterol ndi triglycerides,
• kuzindikira kwa mapuloteni mumkodzo.

Kunenepa kwambiri pamimba ndicho chizindikiro chachikulu. Kachiwiri ndi ochepa matenda oopsa (kuthamanga kwa magazi). Pafupipafupi, munthu samakhala ndi kunenepa kwambiri komanso matenda oopsa, koma kuyezetsa magazi kwa cholesterol ndi mafuta kumakhala koyipa kale.

Kuzindikira kukana insulini pogwiritsa ntchito mayeso kumakhala kovuta. Chifukwa kuchuluka kwa insulin m'madzi a m'magazi kumatha kusiyanasiyana, ndipo izi sizachilendo.Mukamayang'ana insulin yotsalira ya plasma, mankhwalawa amachokera 3 mpaka 28 mcU / ml. Ngati insulini yachilendo kuposa kusala kudya kwa magazi, zikutanthauza kuti wodwalayo ali ndi hyperinsulinism.

Kuchulukana kwakukulu kwa insulini m'magazi kumachitika pamene kapamba amatulutsa owonjezera kuti athe kulipirira insulin kukana. Zotsatira zakuwonetseraku zikuwonetsa kuti wodwalayo ali ndi chiopsezo chachikulu cha matenda a shuga a 2 komanso / kapena mtima.

Njira yeniyeni yovomerezeka yodziwira matenda a insulin imatchedwa hyperinsulinulin insulin clamp. Zimaphatikizapo kulowetsedwa kosalekeza kwa insulin ndi shuga kwa maola 4-6. Iyi ndi njira yotopetsa, chifukwa chake sagwiritsidwa ntchito kwenikweni pochita. Amangolekezera kuyesa magazi magazi chifukwa cha plasma insulin.

Kafukufuku wasonyeza kuti kukana insulini kumapezeka:

• 10% ya anthu onse opanda zovuta zama metabolic,
• mu 58% ya odwala matenda oopsa (kuthamanga kwa magazi kuposa 160/95 mm Hg),
• mwa 63% ya anthu omwe ali ndi hyperuricemia (seramu uric acid imaposa 416 μmol / l mwa amuna ndipo oposa 387 μmol / l mwa akazi),
• mwa 84% ya anthu omwe ali ndi mafuta ambiri am'magazi (triglycerides opitilira 2.85 mmol / l),
• mwa 88% ya anthu okhala ndi cholesterol yabwino “yabwinobwino” (m'munsimu 0,9 mmol / l mwa amuna ndi otsika 1.0 mmol / l mwa azimayi),
• mu 84% ya odwala matenda a shuga a 2,
• 66% ya anthu omwe ali ndi vuto loleza shuga.

Mukakayezetsa magazi a cholesterol - osayang'ana cholesterol yathunthu, koma payokha "zabwino" ndi "zoyipa".

Mitundu imayambitsa kukana insulini

Kukana kwa insulin ndi vuto la kuchuluka kwakukulu kwa anthu onse. Amakhulupirira kuti amayamba chifukwa cha majini omwe adayamba kukhala ambiri panthawi ya chisinthiko. Mu 1962, zidadziwika kuti iyi ndi njira yopulumutsira chakudya nthawi yayitali. Chifukwa imathandizira kudzikundikira kwamafuta m'thupi munthawi yazakudya zambiri.

Asayansi akhala ndi njala kwa nthawi yayitali. Omaliza kupulumuka ndi omwe adapezeka kuti ali ndi chibadwa chokhala ndi insulin. Tsoka ilo, masiku ano, njira imodzimodziyo "imagwira ntchito" pakupanga kunenepa kwambiri, matenda oopsa, komanso matenda a shuga 2.

Kafukufuku akuwonetsa kuti odwala omwe ali ndi matenda amtundu wa 2 ali ndi vuto lakumtunduwu pakufalitsira chizindikiro atalumikiza insulin ndi receptor yawo. Izi zimatchedwa zolakwika za postreceptor. Choyamba, kusamutsidwa kwa glupose transporter GLUT-4 kumasokonezedwa.

Odwala omwe ali ndi matenda a shuga a mtundu wachiwiri, kufooka kwa mitundu ina yomwe imapereka kagayidwe kazakudya zam'mimba ndi lipids (mafuta) zinapezekanso. Awa ndi majini a glucose-6-phosphate dehydrogenase, glucokinase, lipoprotein lipase, mafuta acid synthase ndi ena.

Ngati munthu ali ndi chibadwa chokhala ndi matenda amtundu wa 2, ndiye kuti amatha kuzindikira kapena osayambitsa matenda ashuga. Zimatengera moyo. Zomwe zimayambitsa chiopsezo chachikulu ndimakudya ochulukirapo, makamaka kumwa mafuta osakanikirana (shuga ndi ufa), komanso masewera olimbitsa thupi ochepa.

Kodi chidwi chokhudza insulini m'matupi osiyanasiyana a thupi

Pazithandizo zamatenda, kumva kwa insulin kwa minofu ndi minyewa ya adipose, komanso maselo a chiwindi, ndikofunikira kwambiri. Koma kodi kuchuluka kwa insulin kukokana ndi izi zimakhala chimodzimodzi? Mu 1999, kuyesa kunawonetsa kuti ayi.

Nthawi zambiri, kupondereza 50% ya lipolysis (kuchepa kwamafuta) mu minofu ya adipose, kuchuluka kwa insulin m'magazi osaposa 10 mcED / ml ndikokwanira. Kuti 50% yoletsa kutulutsidwa kwa glucose m'mwazi ndi chiwindi, pafupifupi 30 mcED / ml ya insulin m'magazi ikufunika kale. Ndipo kuti muwonjezere kutuluka kwa glucose pogwiritsa ntchito minofu ya 50%, kufunikira kwa insulini m'magazi a 100 mcED / ml ndiwofunikira ndikofunikira.

Tikukumbutsani kuti lipolysis ndikuphwanya kwa adipose minofu. Kuchita kwa insulin kumalepheretsa, monga momwe amapangira shuga ndi chiwindi. Ndipo minofu ya glucose imatengedwa ndi insulin, m'malo mwake, imachulukitsidwa.Chonde dziwani kuti mu mtundu 2 wa matenda ashuga, malingaliro ofunikira a insulin m'magazi amasinthidwa kumanja, i.e., pakukulira kwa insulin. Njirayi imayamba kalekale shuga asanadziwike.

Kuzindikira kwa minofu ya thupi kupita ku insulin kumachepa chifukwa cha chibadwa chamtsogolo, ndipo koposa zonse - chifukwa cha moyo wopanda thanzi. Mapeto ake, patatha zaka zambiri, kapamba amasiya kulimbana ndi nkhawa zambiri. Kenako amazindikira matenda a shuga enieni. Ndikothandiza kwambiri kwa wodwala ngati chithandizo cha metabolic syndrome chayambika mofulumira.

Kodi pali kusiyana kotani pakati pa insulin kukana ndi metabolic syndrome

Muyenera kudziwa kuti insulin kukana imapezekanso mwa anthu omwe ali ndi mavuto ena azaumoyo omwe samaphatikizidwa ndi lingaliro la "metabolic syndrome". Izi ndi:

• polycystic ovary mwa akazi,
• aakulu aimpso kulephera
• matenda opatsirana
• glucocorticoid mankhwala.

Kukana kwa insulin nthawi zina kumachitika pakubala, ndipo kumadutsa pakubadwa kwa mwana. Amakhalanso amakula ndi zaka. Ndipo zimatengera mtundu wamakhalidwe omwe munthu wokalamba amatsogolera, ngakhale kuti zingayambitse matenda ashuga a 2 komanso / kapena mtima. M'nkhani "" "mupeza zambiri zothandiza.

Zomwe zimayambitsa matenda a shuga 2

Mtundu wachiwiri wa matenda a shuga, kutsutsana kwa insulin, minyewa, chiwindi ndi minyewa ya adipose ndikofunikira kwambiri pakuchipatala. Chifukwa cha kuchepa kwa chidwi ndi insulini, shuga wochepa amalowa ndikutentha mu maselo a minofu. Mu chiwindi, pachifukwa chomwecho, kuwonongeka kwa glycogen kupita ku glucose (glycogenolysis) kumayambitsa, komanso kaphatikizidwe ka glucose kuchokera ku amino acid ndi zina "zopangira" (gluconeogenesis).

Kukana kwa insulin kwa minofu ya adipose kumawonekera chifukwa chakuti kusakanikirana kwa insulin kumafooka. Poyamba, izi zimathetsedwa ndikuwonjezereka kwa pancreatic insulin. Mu magawo amtsogolo a matendawa, mafuta ochulukirapo amapezeka mu glycerin ndi mafuta achilengedwe aulere. Koma nthawi imeneyi, kuchepa thupi sikumabweretsa chisangalalo chochuluka.

Glycerin ndi mafuta aulere acids amalowa m'chiwindi, pomwe lipoproteins yotsika kwambiri imapangidwa kuchokera kwa iwo. Izi ndizinthu zoyipa zomwe zimayikidwa pamakoma amitsempha yamagazi, ndipo atherosclerosis ikupita patsogolo. Kuchuluka kwa glucose, komwe kumawoneka chifukwa cha glycogenolysis ndi gluconeogeneis, kumalowanso m'magazi kuchokera pachiwindi.

Zizindikiro za kagayidwe kachakudya mwa anthu zimatengera chitukuko cha matenda ashuga. Chifukwa kukana insulini kwazaka zambiri kwabwezedwa ndi kuchuluka kwa insulin ndi maselo a beta a kapamba. Zikatero, kuchuluka kwa insulin m'magazi kumawonedwa - hyperinsulinemia.

Hyperinsulinemia yokhala ndi shuga m'magazi ndi chizindikiro cha insulin komanso harbinger wa kukula kwa matenda a shuga a mtundu 2. Popita nthawi, maselo a beta a kapamba amasiya kulimbana ndi katundu, yemwe amakhala wokwera kangapo kuposa masiku onse. Amatulutsa insulini yocheperako komanso yocheperako, wodwala amakhala ndi shuga wambiri komanso matenda ashuga.

Choyamba, gawo loyamba la insulin secretion limavutika, i.e, kutulutsa kwa insulin mwachangu m'magazi poyankha katundu. Ndipo basal (maziko) obisika wa insulin amakhalanso ochulukirapo. Mwazi wa magazi ukakwera, umakulanso minofu ya insulin komanso umalepheretsa kugwira ntchito kwa maselo a beta mu secretion ya insulin. Njira imeneyi yopezera matenda a shuga imatchedwa "glucose toxicity."

Zoopsa pamtima

Amadziwika kuti odwala omwe ali ndi matenda a shuga a 2, kufa kwa mtima kumachulukanso katatu, poyerekeza ndi anthu omwe alibe zovuta za metabolic. Tsopano asayansi ndi akatswiri ochulukirachulukira akukhulupirira kuti kukana insulini ndipo palimodzi, hyperinsulinemia ndi chiopsezo chachikulu cha matenda a mtima ndi sitiroko.Komanso kuopsa kumeneku sikudalira kuti wodwalayo wayamba kudwala matenda a shuga kapena ayi.

Kuyambira m'ma 1980s, kafukufuku wasonyeza kuti insulini imakhudza mwachindunji makoma a mitsempha yamagazi. Izi zikutanthauza kuti ma atherosselotic plaque ndi kuchepetsedwa kwa lumen ya ziwiya kumayenda mothandizidwa ndi insulin m'magazi omwe amayenda kudzera mwa iwo.

Insulin imayambitsa kuchuluka ndi kusunthika kwa maselo a minofu yosalala, kapangidwe ka lipids mkati mwake, kuchuluka kwa ma fibroblasts, kutseguka kwa dongosolo la magazi, komanso kuchepa kwa ntchito ya fibrinolysis. Chifukwa chake, hyperinsulinemia (kuchuluka kwa insulin m'magazi chifukwa cha kukana insulin) ndikofunikira kwambiri pakukula kwa atherosulinosis. Izi zimachitika kale nthawi isanayambike wodwala wachiwiri.

Kafukufuku akuwonetsa kulumikizana kowonekera bwino pakati pa insulin yowonjezera komanso zinthu zomwe zimayambitsa matenda a mtima. Kutsutsa kwa insulin kumabweretsa mfundo yoti:

• kunenepa kwambiri pamimba,
• mbiri ya cholesterol yamwazi imakulirakulira, ndi zolemba zochokera ku cholesterol “yoyipa” pamakoma amitsempha yamagazi,
• Kuchepa kwa magazi m'mitsempha kumawonjezeka,
• Khoma la chotupa cha carotid limakhala lokwera (kuunika kwa mitsempha)

Ubale wolimba uwu udatsimikizika onse mwa odwala matenda a shuga a 2 komanso mwa anthu ena popanda iwo.

Njira yothandiza pochizira matenda a shuga kuyambira magawo 2 a matenda ashuga a 2, komanso bwino asanayambe, ndi m'zakudya. Kunena zowona, iyi si njira yothandizira, koma kokha kuwongolera, kubwezeretsa bwino pang'onopang'ono ngati metabolism yovunda. Zakudya zamagalimoto ochepa omwe amakhala ndi insulin kukana - ziyenera kutsatira.

Pakatha masiku 3-4 kusintha kwa chakudya chatsopano, anthu ambiri amawona kusintha kwaumoyo wawo. Pambuyo pa masabata 6-8, mayeso amawonetsa kuti cholesterol "yabwino" m'magazi imakwera ndipo yoyipa "imagwa." Mlingo wa triglycerides m'magazi umatsika kukhala wabwinobwino. Komanso, izi zimachitika patatha masiku 3-4, ndipo mayeso a cholesterol amasintha pambuyo pake. Chifukwa chake, chiopsezo cha atherosulinosis chimachepetsedwa kangapo.

Maphikidwe a chakudya chamafuta ochepa motsutsana ndi insulin

Palibe njira zenizeni zochizira insulin. Akatswiri odziwa ntchito zamtundu wa majini ndi biology akugwiritsa ntchito izi. Mutha kuthana ndi vutoli mwakutsatira zakudya zamagulu ochepa. Choyamba, muyenera kusiya kudya zakudya zamafuta, ndiko kuti, shuga, maswiti ndi zinthu zoyera za ufa.

Mankhwalawa amapereka zotsatira zabwino. Gwiritsani ntchito kuwonjezera pakudya, osati m'malo mwake, ndipo lankhulanani ndi dokotala wanu kaye za mapiritsi. Tsiku lililonse timatsata nkhani pochiza insulin. Ma genetics amakono ndi microbiology zimagwira zozizwitsa zenizeni. Ndipo tikuyembekeza kuti m'zaka zikubwerazi azitha kuthetsa vutoli pamapeto pake. Ngati mukufuna kudziwa kaye, lembani zomwe timalemba, ndi zaulere.

Mu Seputembala, ndidapitanso ku China, ndipo zidali zosatheka kutsatira keto. Osatero chifukwa kupeza nyama yopanda shuga kungakhale kovuta. Keto ndi LCHF kwa ine ndi machitidwe azakudya, komwe thanzi limabwera koyamba, timayang'anira mtundu wa zogulitsa. Ng'ombe zodyetsedwa bwino, mafuta a azitona ndi ghee ndizopatsa zapamwamba kwambiri ku China. Malita okha a peanut, hardcore okha.

Ndidasiya kudya zokhazikika, ngakhale ndimalumikiza kusala kudya nthawi ndi nthawi ndimatsuka nkhuku yokazinga ku msuzi wokoma ndi wowawasa.

Kutopa kwanthawi zonse, kugona tulo, njala - Ndinaganiza kuti chinthucho chinali choti ndimayenera kuganizira zilankhulo zitatu ndikulankhula zinayi. Zachidziwikire, kuti ndine nyama yonenepa yopusa.

Mu Januware, ndidafika ku Kazan ndipo ndidayamba kufunafuna ntchito. Tsopano ndine katswiri mu nyuzipepala ya pa intaneti "Realnoe Vremya", ndikaweruka kuntchito ndithamangira kukawerenga, komwe kumakhalako mpaka eyiti madzulo. Zakudya zomwe zili mumtsuko, njala yausiku komanso kusowa tulo zimaphatikizidwa.

Posakhalitsa ndidazindikira kuti chakudya changa cham'mawa - mazira awiri omwe amakhala ndi masamba ndi tchizi / nyama yankhumba - amandikhalira ngati oatmeal pamadzi. Pambuyo pa nkhomaliro, ndimakhala ndi zhor chakuthengo, ngakhale gawo langa lokhazikika ndi: sauerkraut + masamba ena, osiyanasiyana momwe angathere, yophika ndi batala / ghee, ndi ng'ombe, osowa nkhumba. Njala "idachepetsedwa" ndi mchere - chokoleti chowawa, mtedza kapena apulo, koma sizinakhale bwino. Nthawi yomweyo, ndinayesetsa kuti ndisatope. Chakudya chamadzulo, chomwe ndimafuna kuthamanga pakati pa maanja, chimangolimbikitsa chidwi changa.

Mavuto osamba abwerera, adayamba kuchepa. Ndalumikiza izi ndi chakudya chamagulu pang'ono komanso katundu wolemera, kotero ndidayamba kuwonjezera chakudya changa masiku atatu kapena anayi aliwonse. Zinandithandiza, ngakhale sanandigwiritse ntchito. Nditafika pansi pamataya mtima, Katy Young @ wow.so.young adalandira positi yochepetsa chakudya. Ndizodabwitsa kuti sindinazengereze kumulembera.

Kutsiliza: Chizindikiro chogwira mtima kwambiri ndi chakudya mutatha kudya. Ingotsimikizirani kuti muli ndi magawo abwino omwe amakukwaniritsani m'mbuyomu. Ndingafotokoze motere: "Ndadya kwambiri, koma apa mphutsi yaying'ono yakhumudwitsa ikupempha maswiti, ipatseni, kenako ndidzakhuta."

Ndi insulin yayikulu, ndizovuta kwambiri kuchepetsa thupi, kotero ngati mumadya chakudya chokwanira ndipo kulemera kwake ndikoyenera, iyi ndi belu lodabwitsa.

Atsikana ayenera kuyang'anira zolephera pamazungulira.

Kukana kwa insulini kumathandizidwanso ndi mutu, kutopa ndi kuperewera, kugona pang'ono, mavuto okhala ndi nkhawa.

Mafuta a soya ndi mafuta ophikira masamba ndipo kutchuka kwake kukukula padziko lonse lapansi. Koma olemera mu mafuta osakwaniritsidwa, makamaka linoleic acid, mafuta a soya amayambitsa kunenepa kwambiri, matenda a shuga, insulin kukana, komanso matenda osokoneza bongo a mafuta aimpso mu mbewa.

Zipangizo ndi njira zakufufuzira

Ofufuza ku Yunivesite ya California ku Riverside anayesa mafuta a soya osintha ma genetically (GMO), omwe adatulutsidwa ndi DuPont mu 2014. Ili ndi mulingo wochepa wa linoleic acid, chifukwa chomwe mafuta, ofanana ndi mafuta a azitona, ndiye maziko azakudya za ku Mediterranean ndipo amawonedwa ngati athanzi. Ofufuzira anayerekezera mafuta amtundu wa soya ndi mafuta a kokonati okhala ndi mafuta achilengedwe ambiri ndi mafuta a soya a GMO.

Zotsatira za ntchito yasayansi

"Tapeza kuti mafuta onse atatu amakweza cholesterol m'chiwindi ndi magazi, ndikupereka nthano yotchuka yomwe mafuta a soya amatsitsa cholesterol yamagazi," adatero Frances Sladek.

"Poyesayesa kwathu, mafuta a azitona amayambitsa kunenepa kwambiri kuposa mafuta a kokonati, ngakhale ochepera pamafuta amkaka a soya, zomwe zinali zodabwitsa chifukwa mafuta a azitona amawona kuti ndi mafuta abwino kwambiri kuposa masamba onse," atero Poonamjot Deol. Zina mwa zoyipa zoyipa zamafuta amnyama zitha kupezeka chifukwa cha kuchuluka kwa asidi wa asidi, chifukwa nyama zambiri za pafamu zimadyetsedwa ufa wa soya. Ichi ndichifukwa chake zakudya zamafuta ambiri zomwe zimakhala ndi mafuta amkaka a soya zimafanana ndi chakudya chamafuta.

Ofufuzawo amakhulupirira kuti kuchuluka kwa mafuta a soya kungakhale gawo lomwe likuthandizira kunenepa kwambiri. Malinga ndi Centers for Disease Control and Prevention, 35% ya akuluakulu ndi onenepa kwambiri chifukwa cha matenda ashuga, matenda a mtima komanso khansa.

"Zomwe tapeza sizikhudzana ndi zinthu zina za soya, monga msuzi wa soya, tofu ndi mkaka wa soya," adatero Sladek. "Kafukufuku wambiri akufunika pa kuchuluka kwa mankhwala a linoleic acid pazinthu zina ndi zina."

Linoleic acid ndi mafuta acofunikira. Anthu onse ndi nyama ayenera kulandira kuchokera ku zakudya zawo. "Koma izi sizitanthauza kuti ndikofunikira kukhala ndi zochulukirapo m'zakudya zathu," adatero Deol."Thupi lathu limangofunika asidi wambiri 1-2%, koma anthu ena amapeza asidi 8-10%."

Ofufuzawo amalimbikitsa kudya mafuta ochepa a soya wamba. Sladek anati: “Ndinkangogwiritsa ntchito mafuta a maolivi okha, koma tsopano ndawaikamo mafuta a kokonati. Mwa mafuta onse omwe tayesa mpaka pano, mafuta a kokonati ali ndi zotsatira zoyipa zochepa za metabolic, ngakhale zimakhala ndi mafuta pafupifupi onse. Mafuta a kokonati amayambitsa mafuta m'thupi, koma ochulukirapo kuposa mafuta a soya wamba. ”

Deol, Poonamjot, et al. "Omega-6 ndi omega-3 oxylipin amathandizira kunenepa kwambiri kwa mafuta a soya mu mbewa." Sayansi inasimba 7.1 (2017): 12488.

Funso: Palibe mfundo yosadziwika bwino m'buku la UD2, Lyle amalankhula zochepetsa thupi komanso kuti kukana insulini kungakhale kothandiza pankhaniyi. Kodi mungandifotokozere malingaliro anu pankhaniyi, chifukwa ndimadokotala wazakudya ndipo ndakhala ndikuganiza ndikuwerenga kuti sizothandiza. Ndimachita chidwi ndi malingaliro atsopano.

Yankho: Izi ndizosemphana ndi malingaliro wamba ndipo sizimagwirizana ndi zomwe anthu ambiri amakhulupirira (ndizovuta kwambiri kuposa zomwe zalembedwa m'mabuku anga kapena pamwambapa). Monga mwachizolowezi, ndikufunika ndikuuzeni.

Momwe mahomoni amagwirira ntchito

Hormoni ndi chinthu chilichonse m'thupi chomwe chimayambitsa china kwina (kusainira mankhwala opangidwa ndi ma cell a thupi ndikukhudza maselo a mbali zina za thupi). Mwaukadaulo, mutha kusiyanitsa ma neurotransmitters (omwe amagwira ntchito kwanuko) ndi mahomoni (omwe amagwira ntchito kwina kapena m'thupi lonse), koma izi ndizambiri zopanda tanthauzo. Chifukwa chake mahomoni amamasulidwa kuchokera ku chiwalo chilichonse kapena minofu ya thupi (mwachitsanzo, chithokomiro kuchokera ku chithokomiro cha chithokomiro, insulini kuchokera ku kapamba), kwinakwake chimamangiriza ku receptor ndipo imakhala ndikuwongolera.

Loko ndi chifungulo ndi fanizo pafupifupi lonse kufotokozera momwe mahomoni amagwirira ntchito. Hormoni ndiye fungulo, ndipo cholandirira chake chokhoma ndicho loko. Chifukwa chake, kiyi imayikidwa mu loko ndi mphamvu yoyendetsera imayikidwa. Hormoni iliyonse imakhala ndi cholandilira chake (monga fungulo limakwanira kukiya), koma pakhoza kukhala china chake chotchedwa mtanda-reactivity, pomwe mtundu wina wa mahomoni umalowa mu mahomoni ena. Palibe chifukwa chodandaulira ndi izi.

Chifukwa chake, insulin ili ndi insulin receptor. Insulin ikamangirira ku cholandilira ichi, zowunikira zimachitika (zomwe zikufotokozedwa pano). Ndipo ma cell a insulin amenewa amapezeka mthupi lonse, muubongo, m'misempha yotupa, m'chiwindi, komanso m'maselo a mafuta. Zitatu zomaliza ndi mfundo zazikulu zomwe muyenera kuda nkhawa.

Tsopano, zinthu zingapo zimazindikira momwe mahomoni amagwirira ntchito bwino (ndiko kuti, kukula kwamalamulo kumachitika). Zitatu zazikuluzo ndi kuchuluka kwa timadzi timeneti (mwanjira ina yambiri, izi zikutanthauza kuti kuthana kwakukulu kumakhudzidwa), momwe ma receptor alili (kuchuluka kwake komwe kumakhudzana ndi mahomoni), ndi zomwe zimatchedwa kuyanjana. Osadandaula ndi izi, ndikuphatikizanso gawo lachitatu lalikulu pakukwanira kwathunthu.

Chifukwa chake, ngati pali mahomoni ambiri m'thupi, ndiye kuti amatumiza mameseji ochulukirapo kuposa momwe amakhala ochepa, ndipo mosemphanitsa. Testosterone yochulukirapo, mwachitsanzo, imanga minofu yambiri kuposa zochepa. Koma izi sizowona nthawi zonse, ndipo ndi pomwe pomwe chidwi cha receptor (kapena kukana) chimayamba. Izi zikuwonetsa momwe wolandirayo amayankhira bwino kapena momwe timavomera. Chifukwa chake, ngati cholandiracho chiri chokhudzidwa, ndiye kuti si kuchuluka kwa mahomoni omwe ali ndi mphamvu yayikulu. Ngati receptor imalephera, ndiye kuti kuchuluka kwakukulu kwa mahomoni sikungakhale ndi vuto.

Chidziwitso: Mwaukadaulo, pakhoza kukhala china chake chotchedwa receptor dzanzi ndi kukana, zomwe ndi zinthu zosiyana pang'ono, koma, kwenikweni, zilibe kanthu apa. Umu ndi momwe mahomoni amagwirira ntchito. Mutu wotsatira.

Kodi insulin imatani?

Pali malingaliro opusa ambiri onena za insulin yoyandama mozungulira (likukhalira, kodi mahomoni amayandama?), Koma taganizirani za insulin kokha ngati kusokonekera kwa mahomoni.Anawonjezera poyankha pakudya zama protein ndi mapuloteni (koma osayankhira mafuta, omwe angayambitse kukana kwa insulin mwanjira zina), insulin imayika thupi m'njira yosungira mphamvu. Koma musaganize kuti izi zikutanthauza kuti mafuta azakudya sangakupatseni mafuta.

Mu minofu ya mafupa, insulini imalimbikitsa kusungirako ndi / kapena kuwotcha mafuta zamafuta. Mu chiwindi, imasiya kupanga shuga. M'maselo amafuta, amathandizira kudzikundikira kwa ma calorie ndipo amalepheretsa kumasulidwa kwa mafuta (amalepheretsa lipolysis). Apa ndipomwe insulin idakhala ndi mbiri yoyipa.

Eya, insulin ndilimodzi mwazizindikiro mu ubongo zomwe zimayenera kuchepetsa njala, ngakhale kuti sizikuyenda bwino. Palinso umboni kuti abambo amayankha kwambiri insulin kuposa azimayi (omwe amayankha kwambiri leptin). Nawonso azimayi amakhala ndi nkhawa kwambiri kuposa amuna.

Kodi kukana insulin ndi chiyani?

Kwenikweni, ndikutanthauza zotsatira za kukaniza kwa thupi. Kukokana kwa minofu ya mafupa kumatanthauza kuti insulini silingasungitse michere monga glycogen kapena kuyambitsa kuyaka kwa glucose. Mu chiwindi, kukana insulini kumatanthauza kuti kuchuluka kwa insulini sikungalepheretse oxidation wa chiwindi. Kukana kwa insulini muubongo kumatanthauza kuti insulin siyigwira ntchito yake yochepetsa njala.

Koma khungu la mafuta likakhala kuti limalephera kukhala ndi insulini, izi zikutanthauza kuti insulini sizingopeza kokha ma calorie, komanso sangathe kuletsa kumasulidwa kwamafuta acid. Werengani chiganizo ichi mpaka chitamveka bwino, ichi ndiye chifungulo cha funso.

Komanso, thupi likayamba kukhala losagwirizana ndi insulin, ndipo insulini imagwira ntchito kwambiri, thupi limafunafuna kuti litulutse insulin yambiri kuti ilipire. Ichi ndi truism (wodziwika bwino) m'thupi, ngati cholandirira sichitha, ndiye kuti thupi limatulutsa zochulukirapo, kuyesera kudzikakamiza yokha kuti igwire bwino ntchito. Koma izi sizigwira ntchito nthawi zonse. Kuphatikiza apo, kuchuluka kwambiri kwa mahomoni nthawi zambiri kumayambitsa kukana kwa receptor. Chifukwa chake, imakhala yoyenda mozungulira.

Kodi chimayambitsa kukana insulini ndi chiyani?

Zinthu zambiri. Zachidziwikire, genetics, ndizosewerera kwambiri, koma sitingathe kuzilamulira, motero timanyalanyaza. Kusagwiritsa ntchito kumachepetsa mphamvu ya insulin, ndipo kuchita pafupipafupi kumawonjezera (sindidzapita pazifukwa). Selo ikadzazidwa ndi michere, mwachitsanzo, minofu ikadzaza ndi glycogen kapena intramuscular triglyceride (IMTG ndiye mtundu wamafuta womwe umasungidwa m'misempha yamafupa) umayamba kugonjera insulini. Ganizirani ngati thanki yathunthu yamafuta, kuyesa kubayira mafuta ambiri mkati mwake kuyambitsa kusefukira, chifukwa kulibe malo.

Zakudya zimakhudza kukana, mwachitsanzo, kudya kwambiri zamafuta ndi mafuta, zimayambitsa kukana kwa insulin. Pakapita nthawi, kudya kwamafuta ambiri kungasinthe kapangidwe ka membala wa cell, komwe kumayambitsa mavuto. Fructose wambiri (mawu osakwanira) angayambitse kukana kwa insulin.

Ndanena pamwambapa kuti kuchuluka kwambiri kwa mahomoni kungapangitse kukana kwa receptor. Chifukwa chake, ngati wina alibe ntchito, adya chakudya chamafuta ambiri, mafuta, ndi ena, amakhala ndi insulini yambiri ndipo izi zimayambitsa kukana. Umu ndi momwe anthu ambiri amakono amakhalira.

Kunenepa kwambiri m'thupi kumakhudzanso insulin. Izi sizachilengedwe ayi, mungapeze anthu osakhazikika omwe ali ndi insulin yolephera komanso anthu ochulukirapo omwe amakonda chidwi ndi insulin. Koma pali kuphatikiza kwabwino kwambiri.

Muyeneranso kumvetsetsa chinthu china chofunikira kwambiri chomwe thupi limayamba kugonjetsedwa ndi insulin.Minofu yofupa (kapena mwina ndiye chiwindi, sindingakumbukire) imayamba kugonjetsedwa, ndiye kuti chiwindi (kapena minofu ya mafupa, ngati chiwindi ndi choyamba). Izi zimabweretsa kuti thupi silingaletse kupanga shuga m'chiwindi (chifukwa chake, zomwe zimakhala m'magazi zimangokhala zamphamvu nthawi zonse). Ndipo pamapeto pake, maselo amafuta amakhala insulin.

Izi zikachitika, zomwe mungawone ndizakuti magazi ali ndi mafuta ambiri acid (hypertriglyceridemia), cholesterol yambiri, glucose wambiri, ndi zina zambiri, zakudya zomwe zikubwera zilibe kumene zingapite. Sitha kusungidwa m'matumba, sangathe kusungidwa mu chiwindi, sungasungidwe mu maselo amafuta. Izi zimayambitsa gulu la mavuto ena.

Zotsatira za insulin kukaniza mafuta.

Zomwe, pamapeto, zimandibweretsa ku nkhani yayikulu. Anthu ambiri amakhulupirira kuti kukana insulini kumapangitsa kuti mafuta azikwana, pomwe ine ndimanena kuti zimathandiza pakuchepa kwamafuta. Zonsezi, ndi zina - chowonadi. Anthu ena makamaka amatulutsa insulin yokwanira chifukwa cha chakudya. Ngati muphatikiza izi ndi ma genulin kapena moyo wokhudzana ndi insulin, ndiye kuti zopatsa mphamvu sizingasungidwe mu minofu, koma zimapita m'maselo a mafuta (komwe insulin ikhoza kugwirabe ntchito). Inde, kukana insulini kumayambitsa kunenepa kwambiri.

Koma taganizirani zomwe zimachitika thupi likagonjetsedwa ndi insulin kwathunthu. Kapena zochitika za m'maganizo momwe mungapangire maselo amafuta osagwirizana ndi insulin. Tsopano insulin sangadziunjike ma calories m'magazi amafuta ndipo sangathe kupondereza kukhathamiritsa kwamafuta. Pankhani ya kuchepa kwamafuta, izi ziyenera kukhala zabwino. Ngati simungasunge mafuta m'maselo amafuta mukamadya ndipo ndikosavuta kupeza mafuta achilendo, zikutanthauza kuti mafuta amasavuta kutayika.

Zikuwoneka kuti thupi likuyesera kukankhira mafuta kutali ndi ma cell amafuta (omwe amakhalanso odzaza) kuti aletse kuchuluka kwamafuta amthupi. Ndipo ndizomwe amayesa kuchita. Pali matani ambiri osinthika pomwe anthu amayamba kunenepa, zomwe zimayenera kupewa mafuta ochulukirapo, ndipo kukana ndi chimodzi mwazomwezo. Kusintha kumeneku sikugwira ntchito bwino.

Ndipo onani ena mwa mfundo zotsatirazi. Pali kalasi ya mankhwala omwe amatchedwa thiazolidinedione kapena glitazones omwe nthawi zambiri amagwiritsidwa ntchito pokonza insulin sensitivity mu kunenepa kwambiri kapena metabolic syndrome. Mafuta okwera kwambiri omwe amapezeka m'magazi ndi mafuta achilengedwe amawononga thupi, ndipo madokotala amafuna kuwachotsa. Koma mankhwalawa amagwira ntchito mwakuwonjezera chidwi cha insulin m'maselo a mafuta. Ndipo mafuta ayamba kukula.

Palinso umboni wina (koma osati onse) kuti insulin sensitivity imalosera kulemera ndi kuchepa kwamafuta ndi insulin kukana. Izi zikufotokozanso chifukwa chake zosagwirizana ndi insulin, koma anthu owonda amakana kulemera, musangosunga ma calories m'maselo amafuta.

Ganizirani nthawi yosavuta yochepetsera kunenepa ndi kutha kwa zakudya zanu mukakhala kuti insulini ikukhudzidwa kwambiri. Ndipo nthawi yosavuta kwambiri yochepetsera mafuta ndi pamene wina ali ndi mafuta ambiri mthupi, ndipo nthawi zambiri amakhala osagwirizana ndi insulin. Ndikuganiza kuti mumvetsetsa.

Onani kuti mukayamba kuphunzitsidwa ndi kunenepa kwambiri, makamaka kuphunzitsa kuchepa thupi (komwe kumatsitsa minofu ya m'mimba ndikulimbikitsa minofu kumverera kwa insulin), makamaka ngati amachepetsa chakudya, amawoneka kuti amatha kuona zodabwitsazi kuchepa kwamafuta ndikupeza mphamvu.

Ganizirani zamitundu iwiri yamphamvu kwambiri yotsitsa mafuta, Clenbuterol ndi Kukula Hormone, yomwe imayambitsa kukana kwa insulin. Koma anthu akaphunzitsa zolimbitsa thupi, kuchepa mphamvu kwa insulin kumapitilira.Minofu imatenga ma calorie omwe sungasungidwe kwina m'thupi (nthawi yambiri).

Zili ngati kuti mu ma calories a thupi amasamutsidwa kuchokera ku maselo amafuta kupita ku minofu. Ndipo ndikuganiza izi ndizomwe zikuchitika. Ntchito, glycogen depletion imawonjezera mphamvu ya minofu yamatumbo kuti insulin. Malingana ngati maselo amafuta amakhalabe osagwirizana ndi insulin, ma calories amapita ku minofu ndikusiya mafuta.

Chowonadi ndi kukana insulini.

Tsoka ilo, kupatula vuto limodzi lokhala ndi kunenepa kwambiri (kapena mukamagwiritsa ntchito mankhwala osokoneza bongo), kukana insulini kumatha kusintha mbali inayo yomwe imayamba. Anthu akamataya mafuta, maselo amafuta amayamba kukhudzana kwambiri ndi insulin (ichi ndi gawo lina chifukwa chake zimakhala zovuta kwambiri kusamutsa mafuta ochulukirapo), ndiye kuti chiwindi (kapena minofu), kenako minofu (kapena chiwindi).

Zachidziwikire, maphunziro amatha kusintha izi. Izi, zowona, ndi chinthu chokhacho champhamvu kwambiri chomwe tingagwiritse ntchito kukonza mphamvu ya insulin. Ndipo mpaka maselo amafuta atayamba kukhala ndi insulin (kachiwiri, zomwe amachita, momwe mafuta m'thupi amayamba kuchepa), mutha kupeza mphamvu kuchokera kumaselo amafuta kupita ku minofu ya mafupa.

Ndipo, mwachiyembekezo, ili ndi yankho la zomwe zidanenedwa mu Ultimate Diet 2.0.

Tsiku labwino! Pamodzi ndi kupita patsogolo kwa zamankhwala, mawu ndi malingaliro atsopano amawonekera.

Lero ndilankhula za matenda a insulin kukana kapena kukana kwa maselo ndi minyewa pakuchitapo kanthu ka insulin, kuwerengera kwa homa ir index, ndizomwe zimayambitsa, zizindikiro ndi chithandizo.

Mawuwa amagwiritsidwa ntchito osati mu endocrinology, komanso mu zida zina zokhudzana, mwachitsanzo, gynecology ndi mtima.

Kodi insulin kukana (IR)

Mawu akuti insulin kukana (IR) ali ndi mawu awiri - insulin ndi kukana, i.e. insulin insensitivity. Kwa anthu ambiri sizikudziwika bwino kuti liwu loti "insulin kukana", komanso tanthauzo la mawuwa, kuopsa kwake ndi zomwe zikufunika kuchitidwa kuti apewe. Chifukwa chake, ndidaganiza zotsogolera pulogalamu yaying'ono ndikukuwuzani zala zanga zokhudzana ndi izi.

M'nkhani yanga, ndidalankhula za zomwe zimayambitsa matenda ashuga, ndipo pakati pawo panali kukana insulini. Ndikupangira kuti muwerenge, ndizofotokozedwa kwambiri.

Monga momwe mumaganizira, insulini imakhudza pafupifupi minofu yonse ya mthupi, chifukwa glucose monga mafuta opangira mphamvu ndi yofunika mu khungu lililonse la thupi. Palinso, zotupa zina zomwe zimapanga shuga m'magazi popanda inulin, monga ma cell a ubongo ndi ma lens amaso. Koma kwenikweni ziwalo zonse zimafunikira insulin kuti izitenga shuga.

Mawu akuti kukana insulin amatanthauza kulephera kwa insulin kugwiritsa ntchito shuga, mwachitsanzo, kuchepa kwake kwa shuga kumachepetsedwa. Koma insulin ilinso ndi ntchito zina zomwe sizigwirizana ndi kagayidwe ka glucose, koma zimayang'anira zochita zina za metabolic. Izi ndi monga:

• mafuta ndi mapuloteni kagayidwe
• malamulo a kukula kwa minofu ndi njira yosiyanitsira mitundu
• kutenga nawo gawo kapangidwe ka mankhwala a DNA ndi majini

Ichi ndichifukwa chake lingaliro lamakono la IR silimachepetsedwa kukhala magawo okhala ndi metabolism, koma limaphatikizanso kusintha kwa kagayidwe ka mapuloteni, mafuta, ntchito ya maselo a endothelial, mafotokozedwe a jini, ndi zina zambiri.

Kodi insulin kukana matenda?

Pamodzi ndi lingaliro la "insulin kukana" pali lingaliro la "insulin kukana syndrome." Dzina lachiwiri ndi metabolic syndrome. Zimaphatikizana ndi kuphwanya mitundu yonse ya kagayidwe, kunenepa kwambiri, matenda ashuga, matenda oopsa, kuwonjezereka kwa chiwopsezo, chiopsezo chachikulu cha atherosulinosis ndi matenda a mtima).

Ndipo kukana insulini kumathandizira kwambiri pakukulitsa komanso kupitiriza kwa matendawa.Sindingangoganiza za metabolic syndrome, chifukwa ndikukonzekera nkhani pamutuwu. Chifukwa chake, ndikukulangizani kuti musaphonye.

Zimayambitsa minofu kukana insulin

Insulin insensitivity si nthawi zonse matenda. Mwachitsanzo, pakati pathupi, usiku, nthawi yakutha msambo, kukana kwa insulin kumawonekera ana. Mwa akazi, kukhudzana ndi thupi kwa insulin kumakhalapo gawo lachiwiri la msambo.

Matenda a metabolic metabolic amapezeka nthawi zambiri zotsatirazi:

• Type 2 shuga.
• Kubwezeredwa kwa matenda a shuga 1.
• Matenda a shuga ketoacidosis.
• Matenda operewera kwambiri.
• Mowa

Kukana kwa insulini kumatha kukhalanso mwa anthu opanda matenda a shuga. Ndizodabwitsa kuti insulin insensitivity imatha kuwonekera mwa munthu wopanda kunenepa kwambiri, izi zimachitika mwa 25% ya milandu. Kwenikweni, ndithudi, kunenepa kwambiri ndi mnzake wokhudzana ndi insulin.

Kuphatikiza pa matenda ashuga, matendawa amatenga matenda a endocrine monga:

1. Thirotooticosis.
2. Hypothyroidism
3. Itsenko-Cushing's syndrome.
4. Acromegaly.
5. Pheochromocytoma.
6. PCOS (polycystic ovary syndrome) ndi kusabereka.

Pafupipafupi IR

• Mu matenda a shuga - mu 83.9% ya milandu.
• Ndi kulolerana kwa glucose - mu 65.9% ya milandu.
• Ndi matenda oopsa - mu 58% ya milandu.
• Ndi kuwonjezeka kwa cholesterol, mu 53,5% ya milandu.
• Ndi kuwonjezeka kwa triglycerides, mu 84.2% ya milandu.
• Ndi kuchepa kwa milingo ya lipoproteins yapamwamba (HDL) - mu 88.1% ya milandu.
• Ndi kuwonjezeka kwa uric acid wambiri - mu 62,8% ya milandu.

Monga lamulo, kukana insulini kumakhala kosadziwika mpaka kusintha kwa metabolic m'thupi kumayamba. Chifukwa chiyani zotsatira za insulin m'thupi zimasokonezeka? Njirayi idaphunziridwabe. Izi ndi zomwe tsopano zikudziwika. Pali njira zingapo zomwe zimatulutsa dzanzi, zomwe zimagwira pamagulu osiyanasiyana a insulin.

1. Pakakhala insulin yachilendo, ndiye kuti kapamba imabisala kale ndi insulin, yomwe singathe kupereka tanthauzo labwino.
2. Pakakhala zachilendo kapena kuchepa kwa chiwerengero cha insulin zolandilira minofu yomwe.
3. Pakakhala zovuta zina zomwe zimachitika m'selo yomweyi pambuyo pakuphatikizana kwa insulin ndi receptor (vuto la postreceptor).

Ma Anomalies a insulin ndi ma receptor ndi osowa kwambiri, malinga ndi olemba, makamaka kukana kwa insulin kumachitika chifukwa cha zovuta za postreceptor za kufalitsa kwa insulin. Muyenera kuti mukudabwa zomwe zingakhudze pulogalamuyi, ndizinthu ziti zomwe zimawalimbikitsa.

Pansipa ndalemba zinthu zofunika kwambiri zomwe zingayambitse zovuta za pambuyo pa receptor:

• M'badwo.
• Kusuta.
• Zochita zolimbitsa thupi.
• Zakudya zopatsa thanzi
• Kunenepa kwambiri, makamaka m'mimba.
• Chithandizo cha corticosteroids, beta-blockers, nicotinic acid, etc.

Chifukwa chiyani kukana kwa matenda a shuga a 2

Malingaliro atsopano a insulin insensitivity development akupangidwa. Ogwira ntchito ku Tula State University, motsogozedwa ndi Myakisheva Raushan, amaika lingaliro molingana ndi momwe kukana insulini kumawerengedwa ngati njira yosinthira.

Mwanjira ina, thupi limateteza maselo ku insulin yochulukirapo, kuchepetsa kuchuluka kwa zolandirira. Zonsezi zimachitika chifukwa mkati mwakakhudzidwa ndi shuga ndi khungu mothandizidwa ndi insulin, zinthu zina zimathamangira mkati, zimasefukira. Zotsatira zake, khungu limafufuma ndikuphulika. Thupi silingalole kufa kwakukulu, chifukwa chake simalola kuti insulini ichite ntchito yake.

Chifukwa chake, chinthu choyamba mwa odwala chotere ndikuchepa kwa shuga chifukwa cha michere, zolimbitsa thupi ndi mankhwala omwe amachotsa kukana. Kukhazikitsa mankhwala osokoneza bongo ndi jakisoni wa insulin kumangowonjezera zomwe zikuchitika komanso kukulitsa kwa zovuta za hyperinsulinism.

Kodi chiwopsezo cha kusazindikira mtima kwa maselo ndi chiyani?

Insulin insensitivity mosakayika imabweretsa kuchuluka kwa insulin m'magazi - hyperinsulinism. Izi zimachitika kudzera mu mayankho osapindulitsa pomwe, chifukwa chosowa insulini, kapamba amayamba kutulutsa insulin yambiri, ndipo amatuluka m'magazi. Ngakhale pali zovuta za kutulutsa kwachilengedwe kwa glucose ndikulimbana ndi insulin, sipangakhale vuto ndi zotsatira zina za insulin.

Choyamba, zotsatira zoyipa za insulin yochulukirapo pa mtima, kapena m'malo mwake, pakukula kwa atherosclerosis, zatsimikiziridwa. Izi ndichifukwa cha machitidwe angapo. Choyamba, insulini imatha kukhala ndi vuto lililonse m'mitsempha yamagazi, ndikupangitsa kuti kukhazikika kwa makhoma awo ndikupangitse kuti ziphuphu za atherogenic zisalowe.

Kachiwiri, insulini imatha kuwonjezera vasospasm ndikuletsa kupuma kwawo, komwe ndikofunikira kwambiri pazida za mtima. Chachitatu, insulini yambiri imatha kukhudza kayendedwe ka coagulation, imathandizira kupindika komanso kuletsa dongosolo la anticoagulation, chifukwa, chiopsezo cha thrombosis chikuwonjezeka.

Chifukwa chake, hyperinsulinism imatha kuyambitsa chiwonetsero choyambirira cha matenda a mtima, kuchepa kwamitsempha, kukwapula, komanso kuwonongeka kwa ziwiya zam'munsi.

Inde, anthu omwe ali ndi insulin kukana ali pachiwopsezo chachikulu chotenga matenda a shuga. Izi ndi mtundu wamalingaliro amoyo a thupi. Poyamba thupi limapanga insulini yambiri kuti likhale ndi shuga athithithi, potero limagonjetsa kukana. Koma posachedwa mphamvuzi zikutha ndipo kapamba sangathe kutulutsa magazi okwanira kuti asungitse shuga m'magazi, chifukwa cha zomwe glucose imayamba kukula pang'onopang'ono.

Poyamba, izi zikuwonetsedwa ndikuphwanya kulekerera kwa glucose, komwe ndidalemba m'nkhani yanga, ndikukulangizani kuti muwerenge, kenako ndi zizindikiro zowoneka za matenda ashuga. Koma akanatha kupewa izi koyambirira.

Kukana kwa insulini ndi chimodzi mwazifukwa zambiri komanso zofunika kwambiri zakusokonekera kwa matenda oopsa a anthu. Chowonadi ndi chakuti insulini yambiri imatha kulimbikitsa chidwi chamanjenje, mwakutero kuwonjezera kuchuluka kwa norepinephrine m'mwazi (mkhalapakati wamphamvu kwambiri yemwe amachititsa kuphipha kwamitsempha). Chifukwa cha kuchuluka kwazinthu izi, mitsempha yamagazi imakhala yotupa ndipo kuthamanga kwa magazi kumakwera. Kuphatikiza apo, insulin imasokoneza njira yopuma ya mitsempha yamagazi.

Njira yina yowonjezera kukakamira ndiyo kusunga madzi ndi sodium yokhala ndi insulin yambiri m'magazi. Chifukwa chake, kuchuluka kwa magazi ozungulira kumawonjezeka, ndipo pambuyo pake pamafunika kuthamanga.

Musaiwale za zotsatira za hyperinsulinemia pamitsempha yamagazi. Kugwiritsa insulini kwambiri kumapangitsa kuchuluka kwa triglycerides, kuchepa kwa lipoproteins yapamwamba kwambiri (HDL - antiatherogenic lipids, i.e., kupewa atherosclerosis), kuwonjezeka pang'ono kwa otsika osalimba a lipoproteins (LDL). Njira zonsezi zimathandizira kupita patsogolo kwa mitsempha ya mitsempha, yomwe imabweretsa zotsatira zoyipa.

Mwa akazi, ndi chizolowezi kuyika chizindikiro chofanana pakati pa polycystic ovary syndrome ndi kukana insulin. Matendawa amayambitsa kuphwanya kwa ovulation, kuyambitsa kubereka, komanso kuwonjezeka kwa androgens ofooka, zomwe zimayambitsa zizindikiro za hyperandrogenism.

Zoyenera kuchita

Ngati mwawerengera nkhaniyi mpaka kumapeto, zikutanthauza kuti mukuyang'anizana ndi vutoli ndipo mukufuna kuphunzira momwe mungagonjetsere matenda amtunduwu ndikupezanso thanzi. Semina yanga yapaintaneti "Kukana insulini ndikuwopseza", yomwe idzachitike pa Seputembara 28 nthawi ya 10:00 nthawi ya Moscow, ikuthandizidwa pa nkhaniyi.

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Ndi chisangalalo ndi chisamaliro, endocrinologist Lebedeva Dilyara Ilgizovna

Zakudya zochepa za carb

Pazinthu zitatu zazikulu zomwe zikufunika kuti zitsimikizire kuti anthu ali ndi moyo, ndimagwiritsa ntchito michere omwe ali ndi udindo wonse wopanga mahomoni. Chifukwa chake, dongosolo lazakudya lomwe lili ndi chakudya chamagulu pang'ono limakhala imodzi mwanjira zothandiza zomwe sizothandiza kuti muchepetse thupi, komanso kuthana ndi matenda ashuga.

Masabata awiri azakudya zoterezi ndizokwanira kuchepetsa kuchuluka kwa mahomoni momwe mungathere ndikuwonjezera chidwi cha insulin.

Onetsetsani kuti mukuwerenga: Kodi mumakhala nthawi yayitali bwanji mukamamatira dongosolo la chikho 10 'Idyani ndi Kutaya Thupi'?

Ngati musamadya zakudya zamafuta ochepa, mudzatha kuchepetsa kuchuluka kwa thupi, kuchepetsa mafuta, kubwezeretsa gawo lanu. Kuphatikiza apo, zakudya zofananira zina zimapanganso kuti magazi a cholesterol akhale m'magazi ndipo zimadziwikitsa magazi. Zonsezi zimatsimikizira kuchuluka kwa kadyedwe koyenera mokhudzana ndi mahomoni.

Apple cider viniga

Quality apple cider viniga ndiye wowonjezera bwino pachakudya chilichonse kapena chophweka, chopatsa thanzi. Izi ndizofunikira ngati zikugwirizana mwachindunji ndi kuyeretsa kwamphamvu kwa thupi ndikuwonda msanga.

Malinga ndi ziwerengero, viniga cider viniga ndi chinthu chapadera m'njira zonse zomwe zimapangidwa kuti zisasinthe mwadzidzidzi kuchuluka kwa insulin ndi kuchuluka kwa shuga.

Zaka zingapo zapitazo, asayansi adatsimikizira kuti kumverera kwodzaza kumakhudzanso mwachindunji ndi kuchuluka kwa asipiki acid. Zatsimikiziridwa kuti masamba osankhidwa ndi zakudya zowotchera zamitundu yosiyanasiyana ndizabwino kuti mukhale ndi thanzi komanso chopatsa thanzi, motero, kuti muchepetse kunenepa.

Malamulo a zopatsa thanzi

Zikondamoyo zimatha kutulutsa ma insulin osiyanasiyana. Zonse sizimangotengera mtundu wa zakudya zomwe zimagwiritsidwa ntchito, komanso kuchuluka kwa zakudya zomwe mumadya. Mwa kudya zopatsa mphamvu zochepa panthawi imodzi komanso pafupipafupi kuposa momwe mumakhalira, mutha kukulitsa chidwi champhamvu chazinthu zonse zamathupi ndikuchepetsa kuchuluka kwake. Njira iyi ndi yabwino kwa anthu onenepa kwambiri.

Zilibe kanthu kuti munthu amatsata zakudya ziti, ndikofunikira kudya magawo ochepa komanso mosamala pambuyo maola awiri ndi atatu.

Kukana kwathunthu shuga

Zakhala zikudziwika kuti shuga ndi imodzi mwazinthu zoyipa kwambiri pa thanzi la munthu. Ndikofunika kupewera kwa aliyense amene akufuna kutsitsa mahomoni m'magazi ndipo akufuna kuchotsa masentimita owonjezera. Kuphatikiza apo, mankhalawo ayenera kutayidwa kwa iwo omwe akufuna kukonza thupi ndikuyesetsa kukhala ndi moyo wathanzi komanso wathanzi.

Ngati kuchuluka kwa shuga m'magazi kumakwezedwa kwambiri mpaka pamlingo wovuta, mudzafunika musangosiya zofunikira zokha, maswiti ndi chokoleti, komanso kuchepetsa kuchuluka kwa zipatso. Zogulitsazi zimakhala ndi fructose, zomwe, ngakhale pang'ono, komabe zimakulitsa insulin ndipo zimakhudza zakudya zilizonse.

Masewera olimbitsa thupi komanso masewera olimbitsa thupi

Maphunziro olimbitsa thupi pafupipafupi amathandizira kuchepetsa insulini, kuthandizira, potero, munthu kuchepa thupi msanga momwe angathere ndikuchotsa mavoliyumu. Monga tawerengera maphunziro ambiri, masewera olimbitsa thupi opangidwira bwino komanso njira yoyenera ndi njira yabwino yowonjezera kukhudzidwa kwathunthu ndi insulin.

Zochita zolimbitsa thupi ndizofunikira kwambiri kwa odwala omwe akhala akudwala matenda ashuga a 2 kwambiri. Anthu awa amalimbikitsidwa kuphatikiza mitundu yosiyanasiyana yophunzitsira kulemera kwamphamvu ndi masewera olimbitsa thupi aerobic. Chifukwa chake mutha kuchepetsa kuchuluka kwathunthu kwa insulin ndikuyamba kuwonda.

Cinnamon

Kuti muchepetse kuchuluka kwa insulini, muyenera kuwonjezera sinamoni ku zakumwa ndi mbale zanu tsiku lililonse. Izi ndizosangalatsa, zonunkhira, komanso zothandiza. Pali ma antioxidants ambiri a sinamoni omwe amachiritsa thupi bwino komanso amateteza ku ngozi ya khansa. Ndikokwanira kudya magalamu awiri okometsera tsiku lililonse ndipo mutha kupeza zabwino zambiri zopindulitsa thupi.

Kukana kwa chakudya chamafuta kwambiri

Zakudya zatsopano zomwe zimakonzedwa, zodzazidwa mwachangu, zopanda mafuta, ndi gawo lalikulu la zakudya zabwino kwa anthu ambiri. Zinthu zoyipa zotere ziyenera kutayidwa.

Kugwiritsa ntchito chakudya chamafuta othamanga kumatha kupangitsa munthu kuthana ndi vuto lalikulu mthupi.

Onetsetsani kuti mukuwerenga: Zimayambitsa kutsika kwa kuchuluka kwa mabere panthawi ya kunenepa kwambiri. Njira zogwira mtima zopulumutsa

Ndi kugwiritsa ntchito kwawo, kuchuluka kwakukulu ndi insulinititity yoopsa sikungapeweke. Nthawi imodzimodzi, zinthu zamafuta oyengereza zimadziwikanso ndi chisonyezo chokwera kwambiri cha glycemic.

GI ndi gawo lapadera lomwe limayesa kuthekera kwazinthu zilizonse kuti zikhudze mwachindunji pamagulu onse a shuga ndi shuga. Kuti mupewe izi, muyenera kuchotsa pamasamba onse zotsekemera, makeke opangira tokha. Izi zitha kusintha bwino zipatso zosavuta.

Kukhala moyo wongokhala ndi njira yachidule yowonjezera shuga

Zakhala zikunenedwa pamwambapa kuti kuti muchepetse insulini yonse mwachangu, ndikofunikira kubweretsa katundu wambiri, wokhazikika ku regimen yatsiku ndi tsiku. Ngati izi sizingatheke, ngati wodwala agwira ntchito, ndikofunikira kuyambitsa ntchito zochepa. Ndikosankha kukaona malo olimbitsa thupi, ndikokwanira kuyenda pang'ono ndikuchita zolimbitsa thupi zazing'ono nthawi ndi nthawi.

Kusala komanso Kusala Kukhazikika

Ngati mungayambitse kudya kwanu pafupipafupi, mutha kulimbitsa thupi kwambiri komanso kuthamanga kwambiri komanso kuchepetsa kuchepa kwa mahomoni. Nkhani yakusala kudya ikuyenera kukambirana ndi dokotala. Amamuyeza mayeso kuchipatala kuti adziwe zolemba ndi nthawi yayitali kuti athe kuchiritsa thupi. Kumbukirani kuti kudziletsa kwa nthawi yayitali komanso njira zochepa zopatsa thanzi zimatha kuchepetsa thanzi la munthu. Chifukwa chake, kufunsa kwa dokotala ndikofunikira kwambiri.

Powona nsanamira ndikofunikira kuti zizisungidwa molondola, komanso bwino kutuluka pazoletsa, makamaka m'malo omwe kudziletsa kunali kokwanira.

CHIKWANGWANI mu chakudya

CHIKWANGWANI ndi chinthu chomwe nthawi zambiri chimasowa mthupi la munthu. Kuyambanso kugwiritsa ntchito zakudya zomwe zimadzazidwa ndi CHIKWANGWANI, zidzakhala zopanda ntchito zambiri kuti muchepetse kunenepa.Kodi fiber imagwira ntchito bwanji? Phindu lalikulu la chinthuchi limatengera kuthekera kwake kotenga madzi ndi kuthekera kwa kusinthika kukhala mtundu wa ma gel mukalowetsedwa. Imachepetsa kuyenda kwa chakudya kudzera m'mimba ndi matumbo. Izi zimachepetsa kumverera kwa kuchuluka kwa njala ndikusunga mokwanira gawo la insulin. Ngati mukufuna kudzaza zakudya zanu ndi CHIKWANGWANI, muyenera kuyika mndandanda wazinthu zofunikira monga:

• Ma smoothies obiriwira okhala ndi mitundu yonse ya zipatso ndi zipatso zina,
• Mapulani osiyanasiyana ogulitsa tirigu. Ayenera kulocha m'malo opukutidwa ndikutsuka,
• Mitundu yosiyanasiyana yamasamba

• Malemu omwe amapanga thupi labwino, mtedza ndi mbewu za fulakesi.

Zakudya zamafuta ambiri zimatha kuchepetsa kuchuluka kwa insulin m'magazi, kulimbitsa mwachangu ndikubwezeretsa ntchito ya mtima ndi mitsempha yamagazi ndikuwongolera magwiridwe antchito.

Kumwa tiyi wobiriwira

Chakumwa chatsopanochi ndichothandiza kwambiri kwa munthu aliyense. Tiyi imakhala ndi antioxidant wapadera yemwe amadziwika kuti catechin. Malinga ndi kafukufuku, izi zimapereka thandizo lofunikira polimbana ndi insulin.

Nsomba ndi mafuta athanzi

Pali zifukwa zambiri zodya zakudya zamafuta. Izi sizokhudzana ndi zakudya yokazinga, koma nsomba zomwe zili ndi thanzi potengera zamafuta ndi zakudya zina. Munthu yemwe ali ndi insulini yokwera kwambiri amafunika kuphatikiza zakudya zotsatirazi tsiku lililonse:

1. Hell, mafuta onenepa, mackerel osowa, sardines,
2. Avocado
3. Mbewu ndi mtedza,
4. Mafuta A Azitona Osasankhidwa,
5. Yogati yachi Greek.

Zogulitsa zoterezi zimakhala ndi Omega-3 komanso mapuloteni apamwamba kwambiri. Adzakhala ndi phindu lofunikira mthupi.

Onetsetsani kuti mukuwerenga: Zosankha zogwiritsira ntchito ma cloves ngati mukufuna kuchepetsa thupi

Malinga ndi kafukufuku wambiri, anthu omwe ali ndi vuto la insulin komanso kudya mafuta athanzi mwachangu amachepetsa kukana kwawo konse. Zakudya zamafuta zimakhala ndi zotsatira zabwino mthupi.

Kudya Mapuloteni Oyenera

Kudya kwa mapuloteni amtundu wa tsiku ndi tsiku kumathandizira kuti asamangoyang'anira bwino kulemera ndi magawo a thupi, komanso kuchuluka kwa insulin. Mapulogalamu ofanana atha kupezeka pazinthu zomwe zatchulidwa pamwambapa, komanso kuchokera ku nkhuku yazakudya ndi nyama ya Turkey. Amalangizidwanso kudya nyama yanyama yokhazikika.

Ndikofunika kukumbukira kuti sizinthu zonse zomwe zimapanga mapuloteni komanso osagwiritsidwa ntchito mwanjira iliyonse ndizothandiza kwa anthu.

Ngati mumagwiritsa ntchito mapuloteni ambiri, amatha kuyambitsa zotsatirapo zake. Zotsatira zofananazo zimatheka ndi kumwa kwambiri whey ndi casein wamba, omwe amapezeka mkaka, komanso ng'ombe. Ngati mumagwiritsa ntchito mankhwala ochulukirapo, mutha kupeza kulumpha kwakamafuta, komwe kumawonedwa mwa munthu wathanzi mukatha kudya mkate. Izi zikusonyeza kuti muyenera kusamala ndi mapuloteni.

Malangizo Onse & Machenjezo

Pamodzi ndi malangizo onse omwe aperekedwa pamwambapa, madokotala amakulangizani kuti mugone kwambiri. Ngati palibe njira yowonjezerera kwambiri nthawi yonse komanso nthawi yayitali yogona, ndiye kuti zonse ziyenera kuchitidwa kuti zizikhazikika. Kugona kopumula komanso kupumula kopezeka m'moyo wa munthu, kumakhala kokhazikika kwambiri monga kuchuluka kwa mahomoni m'thupi lake. Mukamayang'anira mahandiredi anu nthawi zonse, mudzatha kuugwira bwino.

Ngati mukufuna kupeza zotsatira zabwino zochepetsera thupi, njirayi ikhale yothandiza kwambiri.

Kuphatikiza pokhazikitsa kugona kwanu, kupumula komanso kudya bwino, muyenera kulabadira maupangiri ena owonjezera:

• Ndikofunikira kuyang'ana pa chipambano ndikulemba zomwe wakwaniritsa.
• Ndikofunika kuti mupange mndandanda wazolamulira tsiku lililonse. Ndikofunikira kulemba malamulo ndi mawonekedwe azakudya momwemo, komanso kukonza chakudyacho.
• Ndikofunika kumalemba nthawi zonse za inu, komanso za zinthu zomwe muyenera kuzigwiritsa ntchito tsiku ndi tsiku, kusintha ndi kuchiritsa thupi lanu.
• Ngati kuli kudzikayikira pang'ono, ndibwino kufunsa m'modzi wa abalewa kuti asayang'ane njira yopewera zakudya zopatsa thanzi komanso kukhala ndi moyo wathanzi.

Nthawi yomweyo, chisamaliro chapadera chiyenera kulipidwa panthawi yonse ya chithandizo. Palibenso chifukwa choyesera kuti musinthe masinthidwe anu, muyenera kuchita pang'onopang'ono kuti musayambitse thupi kupsinjika. Kusintha kulikonse kumatenga nthawi, zomwe ndizofunikira kwambiri thanzi lanu.

Musasinthe zakudya zanu mwachangu kwambiri, pofuna kuchepetsa kulemera kwakukulu komanso kuchuluka kwa mahomoni, pang'onopang'ono ndikofunikira. Muyenera kuyamba ndi kupatula zakudya zina pamenyu, kenako pang'onopang'ono kuyambitsa zakudya zamafuta ndi zakudya zamafuta m'zakudya.

Mukuchira, simukuyenera kulola kuchuluka kwa fiber ndi zakudya zopatsa thanzi. Izi zimayenera kugawidwa m'magawo ndipo zimadyedwa m'malo osiyanasiyana tsiku lonse. Komanso musaiwale za kusiyanasiyana. Ndikofunikira kugawa zakudya zama protein, mafuta ndi masamba osatha, osayang'ana pa chinthu chilichonse.

Pomaliza

Kutengera ndi zomwe tafotokozazi, titha kunena kuti ndi insulin yowonjezereka yomwe nthawi zambiri imapangitsa kufooka kwa zoyesayesa zonse zokhudzana ndi kuchepa thupi. Ndikofunikira kuganizira kafukufuku wamasiku ano ndikudya zakudya zopatsa thanzi zomwe zimathandizira kuchepetsa insulin. Izi zimachotsa chiopsezo chotenga matenda owopsa a shuga ndikuwongolera kwambiri thupi.