Fomu kapena metformin

Pali mitundu yambiri ya mankhwala Glucofage. Ku Russia, mwachitsanzo ndi Fomu la Metetin ndi Metformin. Ndi mphamvu ya zochita iwo ali chimodzimodzi.

Mankhwalawa ndi a anthu odwala matenda ashuga. Amakhala ndi mawonekedwe ofanana ndipo amagwirizana ndi mitundu yochepetsa shuga. Zitha kugulidwa kokha ndi mankhwala. Zomwe zili bwino kuchokera ku mankhwalawa, dokotala yemwe amapezekapo amawunikira, kuyang'ana momwe zinthu ziliri, zotsatira zoyesa ndikuwunika.

Ali ndi mawonekedwe apiritsi yotulutsidwa. Chofunikira chachikulu pakuphatikizidwapo ndi pawiri wa dzina lomweli. Amapezeka mu Mlingo wa 500 ndi 850 mg.

Metformin ili ndi chinthu chofunikira kwambiri cha dzina lomweli.

Mankhwala ndi a gulu la Biguanides. Kupanga kwamankhwala kumapangidwa ndikuwonetsa kulepheretsa kupanga kwa chiwindi mu chiwindi ndikuchepetsa mayamwidwe ake m'matumbo. Mankhwala samakhudzana ndi kupanga kwa insulin mu kapamba, motero palibe chiopsezo cha hypoglycemic reaction.

Mankhwalawa ali ndi phindu pamtima wamatumbo, amaletsa kukula kwa angiopathy mu shuga.

Mothandizidwa ndi pakamwa pakumwa mankhwala, muyezo waukulu wa yogwira pophika umapezeka m'magazi 2,5. Kuyamwa kwa piritsi kumayima maola 6 mutatha kumwa mapiritsi. Kuchotsa hafu ya moyo wa chinthucho ndi pafupifupi maola 7. Bioavailability wafika 60%. Amathira mkodzo.

Zizindikiro zogwiritsidwa ntchito Metformin - matenda osokoneza bongo a mitundu yoyamba komanso yachiwiri. Mankhwalawa amatchulidwa ngati njira yothandizira insulin mankhwala komanso kugwiritsa ntchito mankhwala ena, popeza kuyanjana kwa mankhwalawa kwawonetsa zotsatira zabwino. Metformin imalembedwanso monga chida chachikulu munthawi yamankhwala.

Mankhwalawa amagwiritsidwa ntchito ngati kunenepa kwambiri, ngati mukufuna kuwongolera kuchuluka kwa shuga m'magazi, bola ngati zakudya sizipereka zotsatira zabwino. Mankhwala ena amatha kuthandizira kuti apezeke ovomerezeka a polycystic, koma mu nkhani iyi, mankhwalawa amagwiritsidwa ntchito moyang'aniridwa ndi dokotala.

Mankhwala amapezeka mu mawonekedwe a mapiritsi oyera. Chofunikira chachikulu ndi metformin.

Piritsi 1 ili ndi 500, 850 ndi 1000 mg ya chinthu. Mankhwalawa adapangira pakamwa.

Mankhwalawa amaperekedwa kwa anthu odwala matenda a shuga a 2 pomwe zakudya sizithandiza. Mankhwalawa amagwiritsidwanso ntchito pakuchepetsa thupi. Mothandizidwa ndi insulin.

Kodi pali kusiyana kotani?

Kusiyana pakati pa Metformin ndi Formmetin kumangopezeka m'mapiritsi. Zogulitsa zonsezi zimakhala ndi povidone, magnesium stearate, croscarmellose sodium, madzi. Koma Metformin ilinso ndi gelatinized starch ndi microcrystalline cellulose.

Mapiritsiwo ali ndi chipolopolo, chomwe chimakhala ndi talc, sodium fumarate, utoto.

Pogula mankhwala, ndikofunikira kuyang'anira zomwe zili pazinthu zothandizira: akapanda kukhala, aposa.

Zomwe zimakhala zotsika mtengo

Mwa mankhwala onsewa, opanga ndi makampani monga Canon, Richter, Teva, ndi Ozone.

Mlingo wa mankhwala ophatikizira piritsi limodzi ndi 500, 850 ndi 1000 mg uliwonse. Pamtengo, onse a Metformin ndi Formmetin ali mgulu lofanana: woyamba ungagulidwe ku Russia pamtengo wa pafupifupi ruble 105 kwa phukusi la mapiritsi 60, ndipo chachiwiri, mtengo wake uzikhala pafupifupi ma ruble 95.

Kodi metformin kapena formin yabwino ndi chiani?

Mankhwala onse awiri, chinthu chachikulu chomwe chimagwiritsidwa ntchito ndi chinthu chimodzi - metformin. Pankhaniyi, mphamvu zamankhwala ndizofanana. Komanso ndalama izi zimasinthana.

Dokotala wokhayo ndi amene angadziwe mankhwala omwe ali abwino kwa wodwala aliyense, kutengera momwe alili.

Potere, m'badwo, momwe thupi limakhalira, momwe wodwalayo alili, mawonekedwe ndi kuuma kwa matendawo zimawerengedwa.

Ndi matenda ashuga

Mu matenda a shuga a mtundu woyamba, pakakhala kuphwanya kwathunthu kapena pang'ono pazomwe zimapangidwira insulin, Metformin ndi Formmetin amagwiritsidwa ntchito kuti achepetse kuchuluka kwa inshuwaransi, kuwonjezera mphamvu ya mankhwala, kusinthira ku mitundu yatsopano ya insulin (kukhala otetezeka panthawiyi), komanso kupewa kunenepa kwambiri.

Mu matenda a shuga amtundu wachiwiri, mankhwalawa amayenera kumwa pafupipafupi. Amathandizira wodwalayo atavulala kwambiri minyewa yomwe imayamba kutulutsira insulin. Chifukwa cha njirazi, mwayi wokhala ndi zovuta za matenda a shuga umachepa.

Ndemanga za Odwala

Sergey, wazaka 38, ku Moscow: “Matenda a shuga a 2 adapezeka. Ndakhala ndikutenga Metformin motsatana ndi jakisoni wa insulin kwa chaka chimodzi. Chidacho chimathandizira kuchepetsa shuga. Ndine wokhutira ndi mankhwalawa, sizinadzetse mavuto. ”

Irina, wazaka 40, Kaluga: "Forethine adapezeka monga adauzidwa ndi adokotala. Shuga ndi wabwinobwino, koma pali vuto la kunenepa kwambiri. Mofananamo, ndinasinthira ku chakudya chamafuta ochepa. Kuyambira pachiyambireni zovuta chonchi mankhwala atha kale kuchepa thupi ndi 11 kg. Khungu layamba kuyenda bwino. ”

Mtundu wachiwiri wa matenda ashuga, mankhwalawa amayenera kumwedwa nthawi zambiri.

Ndemanga za madotolo za Metformin ndi Formetin

Maxim, endocrinologist, wazaka 38, ku St. Petersburg: "Ndimaona Metformin ngati mankhwala othandiza kuchiritsa matenda a endocrine system (matenda a shuga, matenda a kagayidwe kazakudya). Koma nthawi yomweyo, ndimachenjeza odwala anga za zovuta zomwe zimachitika kawirikawiri. Mankhwalawa angagwiritsidwe ntchito pawokha komanso palimodzi popereka chithandizo. ”

Metformin ndi formin - kufotokoza ndi kuchitapo kanthu

Mankhwala Metformin ndi Formmetin ndi mankhwala am'mlomo a hypoglycemic (hypoglycemic), ndi amtundu wa Biguanides. Mankhwala onse omwe amapezeka ku Russia amapangidwa ku Russia ndipo amagwiritsidwa ntchito kwambiri kwa odwala matenda ashuga.

Mankhwala amakhala ndi chinthu chogwira - metformin (metformin hydrochloride).

Mtengo wamankhwala ulinso m'gulu lomweli - Formetin imawononga mapiritsi 95 / ma 60, mtengo wa Metformin ndi ma ruble 105 pa phukusi lomweli. Akatswiri amalimbikitsa kuti azisamalira omwe atenga mbali - akapanda kutero, zotsatira zake zimakhala zabwino, amachepetsa chiwopsezo cha mavuto. Zinthu zomwe zimakonda mitundu yonseyi ndi:

• magnesium wakuba,
• povidone
• madzi
• croscarmellose sodium.

Metformin kuwonjezera ilinso ndi cellcose ya microcrystalline, pregelatinized starch. Mankhwala amakampani ambiri ali ndi zokutira zamafilimu zozikidwa pa utoto, talc, sodium stearyl fumarate. Ndalama zonsezi zimaperekedwa ndi makampani monga Teva, Richter, Canon, Ozone ndi ena ambiri. Mlingo - 0,5, 0,85, 1 g.

Chifukwa cha zotsatira zomwezo, mankhwala amasinthana. Kulandila kumayambitsa kulepheretsa kwa gluconeogenesis m'maselo a chiwindi, omwe amachititsa kuchepa kwa shuga m'magazi. Komanso kuyamwa kwa shuga kuchokera m'mimba thirakiti kumachepa, kugwiritsidwa ntchito kwa glucose omalizidwa m'misempha yosiyanasiyana kumakulanso. Mankhwalawa alibe phindu lililonse pakuwonjezeka kwa insulin sensitivity mu minofu ya adipose, koma amathandizira kukonza chizindikiro ichi mu minofu minofu.

Chizindikiro chovomerezeka

Kusankha zomwe zili bwino - Formmetin kapena Metformin - malinga ndi kuwonetsa sizikumveka. Mankhwala onse awiriwa ali ndi cholinga chomwecho ndipo amatengedwa pamankhwala ofanana. Mtundu wa 1 wa matenda ashuga, womwe umachitika ndikuphwanya insulin kwathunthu, umafunika chifukwa cha izi:

• kuchepetsa insulin
• mankhwala a insulin,
• nthawi yosinthira ku mitundu yatsopano ya insulin (pazifukwa zachitetezo),
• kunenepa kwambiri kupewa.

Mtundu wachiwiri wa matenda ashuga, metformin ndi formin amafunikira pafupipafupi. Popeza chidwi cha maselo kupita ku insulin chimadwaladwala kwambiri matenda amtunduwu, mankhwalawa adzawongolera kwambiri. Zotsatira zake, mwayi wamavuto amachepa. Mankhwala amathandizidwa kuti azitha kudya, kuwonjezera pa zakudya, kuwonda. Mankhwala osokoneza bongo amasonyezedwa makamaka chifukwa cha kunenepa kwambiri.

Mankhwala ofanana limodzi amachepetsa kuchuluka kwa triglycerides ndi cholesterol m'magazi.

Kuphatikiza pa zotsatira zabwino za lipid metabolism, metformin imalepheretsanso magazi kuundana. Imachepetsa mapuloteni apadera omwe amathandizira magazi. Izi zimathandiza kuchepetsa chiopsezo cha stroke, kugunda kwa mtima.

Malangizo a mankhwala

Imwani mapiritsi osafuna kutafuna, osasamba, ndi madzi (okwanira). Kulandila ndi pambuyo pa chakudya, kapena panthawi ya chakudya. Kuchuluka kwa Mlingo kumatengera kuopsa kwa matenda ashuga. Mutha kugwiritsa ntchito mankhwala osokoneza bongo a monotherapy, kuphatikiza mankhwala ndi mankhwala ena amodzimodzi.

Malangizo a mtundu wa regimen ndi awa:

• kumayambiriro kwa mankhwalawa - 1-1,5 g / tsiku, pogawa nambala ya Mlingo wofunika (nthawi zambiri 3),
• Pakatha sabata kapena masabata awiri, mutha kuwonjezera kuchuluka kwa momwe mungafunikire kuti musinthe shuga,
• mukachulukitsa mlingo pang'onopang'ono, zidzakulitsa kulolerana, zimayambitsa zovuta zochepa ndi m'mimba,

Mankhwala amatha kuledzera ndi insulin. Panthawi imeneyi, muyeso woyambira umakhala wotsika - 500-850 mg / tsiku, womwe umagawidwa pazigawo zitatu. Mlingo wa insulin amasankhidwa ndi katswiri potengera magazi. Mankhwala onsewa amatha kuperekedwa kwa ana kuyambira zaka 10. Mlingo woyambirira ndi 0,5 g / tsiku kamodzi madzulo, ndi chakudya. Pambuyo pa masabata awiri, mlingo umasinthidwa molondola, kuchuluka kwakukulu / tsiku ndi 2 g.

Contraindication ndi zoyipa

Pali zotsutsana zambiri pamankhwala awa, pakati pawo pali tsankho, thupi lawo siligwirizana, komanso pali zovuta zingapo za odwala matenda ashuga:

• ketoacidosis
• precoma chikomokere
• kulephera kwa impso,
• kusowa kwamadzi,
• matenda oopsa
• zinthu zadzidzidzi

Mankhwala amaletsedwa kumwa pambuyo povulala, pakapita nthawi opareshoni yayikulu. Poterepa, ndi mtundu wina uliwonse wa matenda ashuga, amasintha kupita ku insulin. Mankhwala sakhazikitsidwa pa nthawi yoyembekezera, musanayambe maphunziro a radiopaque (masiku awiri).

Amalandira mosamala mu ana azaka 10, odwala oposa 65 zaka, pamene mkaka wa m`mawere.

Kugwiritsa ntchito mankhwala kwa nthawi yayitali ndi metformin popanda zosokoneza kungasokoneze mayankho a B. Pakati pazotsatira zake ndizovuta zam'maso, kupweteka kwam'mimba, nseru, kusanza, ndi m'mimba.

Kulakalaka kutha kuchepa. Nthawi zambiri, zotsatirazi zonse zimatha pambuyo pa masiku 14 achithandizo. Ngati zizindikiro za m'mimba zikuwoneka, mapiritsi amayenera kumwa ndi zakudya. Mwapadera, chiwindi (chosinthika), khungu lawo siligwirizana.

Analogi ndi zina ziti zomwe muyenera kudziwa?

Pakati pa analogues pali mankhwala angapo - ochokera kunja ndi omwe amachokera kumayiko ena, omwe amaphatikizidwa ndi metformin kapena chinthu china chogwira ntchito ndi hypoglycemic. Mankhwala ena ndi mahomoni (mwachitsanzo, pamaziko a gliclazide):

Mankhwalawa, ndikofunikira kuti mumayese magazi ndi mkodzo komanso magazi kuti muone ntchito ya impso. Popeza lactic acidosis imapangidwa mwa odwala ambiri pomwe akumamwa mankhwala, ndikofunikanso kuyang'ana kupezeka kwa lactate m'magazi 1-2 nthawi / chaka (chinthu chomwecho chikuyenera kuchitika kupweteka kwa minofu). Ndi kuphatikiza kwa insulin, kuyang'anira shuga ndikofunikira kwambiri, kuyenera kuchitidwa tsiku ndi tsiku. Kulandila ndi othandizira ena a hypoglycemic kumatha kukhala koopsa ndikaponya shuga. Ngati mukumva kufooka, kunjenjemera, kukomoka, ndi zizindikiro zina za hypoglycemia, muyenera kuchitapo kanthu mwachangu kunyumba kapena kukaonana ndi dokotala.