Matenda a shuga ndi chilichonse chokhudza izi

Zatsimikizidwanso kuti Actovegin imathandizira kuchira. Tiyenera kudziwa kuti chithandizo cha Actovegin chimavomerezedwa bwino ndi odwala ndipo sichimapereka mavuto (kupatula zomwe zimachitika kawirikawiri) : mwa anthu osalolera mankhwala).

Asanakhazikitsidwe kwa Actovegin, ndikofunikira kuti mupange kuyesa kwa kulekerera kwa mankhwala!

Poyerekeza ndi matenda ashuga, osati polyneuropathy (PN) okha, komanso angiopathy. Komabe, funso la angiopathies oyambilira komanso apamwamba okhudzana ndi matenda a shuga amakhalabe lotseguka.

Lero ziwerengero motere:matenda a mtima ndi omwe amachititsa kuti anthu opitilira theka a odwala matenda ashuga aphedwe.
Awa ndi matenda a mtima, stroko komanso matenda a shuga.

Zomwe zimayambitsa kukhazikika kwa zovuta pamwambazi, zomwe nthawi zambiri zimatha ndi imfa, ndi matenda oopsa, hyperglycemia, hyperinsulinemia, insulin kukana.

Za udindo wa Actovegin mu chithandizoubongo ischemia ndi stroko Utha kuwerengera mu nkhani ya "Actovegin ndi stroko", komanso zamankhwala zovomerezeka zomwe ambiri amavomereza matenda ashuga polyneuropathy ndi zovuta zina - mu nkhani ya "Actovegin jakisoni" . Mutha kuwerengenso ndemanga za omwe agwiritsa ntchito Actovegin, ndi mtengo wa mankhwalawo.

Kugwiritsa ntchito kukonzekera kwa enzyme sikusokoneza shuga Chiboni (musanagwiritse ntchito, funsani dokotala wanu), yemwe amathandiza kapamba. Odwala omwe ali ndi matenda ashuga, matenda a shuga a m'magazi amayamba, pomwe kuthamangitsidwa kwa chakudya m'mimba kumachepa.
Ambiri mwa odwala ali ndi kuchepa kooneka osati mu endocrine, komanso exocrine pancreatic ntchito (Chilolezo chokhalamo). Woyamba kutsimikizira izi mu zaka khumi ndi zisanu ndi zinayi ndi zitatu ndi H.Pollard. Kukhala kwokhazikika ndi matenda ashuga nthawi zambiri kumakhala kofatsa kapena kwapakati, koopsa (kokhala ndi steatorrhea) sikofala kwambiri. Ndi matenda ofanana ndi kapamba, mankhwala a Creon amathandiza. Tikukulimbikitsani kuti muzidziwitsa za kukonzekera kwa enzymeyi ndi mitundu yake (komanso apa ndi apa).

Chifukwa chake, kukhathamira kwa Actovegin, zosowa zina za mankhwalawa, kuopsa kwa matenda onga matenda a shuga, amalankhula m'malo mwake kugwiritsa ntchito kwake kupewa mavuto.

Mudzalandira zambiri pazamankhwala azovuta za shuga monga matenda ashuga encephalopathy ngati muwerenga nkhaniyi pamankhwala ophatikizira Actovegin ndi Instenon monga gawo la zovuta mankhwala.

Ndipo apa mutha kuwona kanema wamomwe mungapangire bwino intramuscular uk ol.

Kupanga ndi mawonekedwe a kumasulidwa

Actovegin ya mankhwala imapezeka m'mitundu iyi: gel, mafuta ndi zonona, njira yothetsera kulowetsedwa, yankho la jakisoni, mapiritsi. Kuphatikizidwa kwa mitundu yonse yomasulidwa kumakhala ndi zinthu zomwe zimachotsedwapo. Kuphatikizidwa kwa gel kumakhala kuwonjezeredwa 20 ml ya chigawo, mafuta ndi zonona - 5 ml, mu njira yothetsera kulowetsedwa - 25 ml, yankho la jakisoni - 40 mg, pamapiritsi ogwiritsira ntchito pakamwa - 200 mg.

Zizindikiro zogwiritsidwa ntchito

Mankhwala Actovegin amagwiritsidwa ntchito polimbana ndi matenda a shuga 2, pamene wodwala ali ndi izi:

• cholakwika m'magazi a magazi, magazi okwanira akangolowa mu ubongo,
• Zotsatira za stroko,
• zilonda zam'mutu,
• kuphwanya umphumphu wa khungu,
• zilonda zam'mimba
• amayaka.

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Malangizo ogwiritsira ntchito

Mankhwala Actovegin a 2 shuga, malingana ndi mawonekedwe ake amasulidwe, amagwiritsidwa ntchito pakamwa, kunja, jekeseni kapena kulowetsedwa.Malangizo ogwiritsira ntchito akuwonetsa kuti njira yolowerera kapena kulowetsedwa ndiyabwino kwambiri komanso yothandiza. Pa kulowetsedwa kwa mankhwalawa, amapaka shuga ndi mchere wochepa. Njira yochizira pamilandu iyi ndi pafupifupi njira 20. Ngati tikulankhula za mapiritsi "Actovegin", amaikidwa makamaka pazidutswa 2 katatu patsiku. Pankhaniyi, malonda sayenera kutafunidwa, ayenera kutsukidwa ndi madzi ambiri.

Mafuta onunkhira ndi Actovegin amagwiritsidwa ntchito kwanuko. Mankhwalawa amagwiritsidwa ntchito pofuna kuchiza khungu kapena kuvulala. Kuti muchotse zilonda zomwe zimapangidwa posiyana ndi mtundu wa matenda ashuga amtundu wa 2, tengani thandizo la mafuta, omwe amayenera kupaka pakhungu. Kenako bandeji yakuda imayikidwa pamwamba, yomwe siyiyenera kuchotsedwa masiku awiri. Ngati khungu lomwe lakhudzidwalo ndi lonyowa, kuvala kumayenera kusinthidwa tsiku lililonse.

Contraindication

Osati mankhwala Actovegin a shuga, pomwe wodwala ali ndi izi:

• ana osakwana zaka 3,
• thupi lawo siligwirizana ndi zigawo zikuluzikulu za mankhwala,
• nthawi yapakati
• yoyamwitsa
• nkhawa za mtima,
• kusayenda bwino kwamapapu
• kusokonezeka kwamadzi kuchotsedwa m'thupi.

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Zizindikiro zoyipa

Malangizo ogwiritsira ntchito "Actovegin" akuti nthawi zambiri mankhwalawa amaloledwa ndi odwala ndipo samayambitsa zovuta. Komabe, milandu ya chitukuko cha zizindikiro zoyipa idawonedwa ndikuwonetsedwa mu mawonekedwe a:

• maonekedwe a kudzikuza,
• kuchuluka kwa thupi kutentha
• thupi lawo siligwirizana.

Madokotala amati makamaka, mankhwalawa amakhudza kwambiri ntchito ya mtima. Pankhaniyi, wodwalayo amadandaula kuti akupuma mwachangu, kuwonjezeka kwa magazi, kuwonongeka kwa thanzi, mutu, komanso kukomoka. Ngati "Actovegin" watengedwa pakamwa, ndipo Mlingo wofotokozedwa ndi adotolo wasokonezeka, nthawi zina pamakhala kugunda kwa mseru, kusanza komanso kupweteka m'mimba.

Ngati wodwalayo ali ndi vuto laumoyo komanso kukula kwa zizindikiro zam'mbali, ndikofunikira kulumikizana ndi achipatala msanga, komwe dokotala amapita kukayesa ndikupereka mayeso ofunika. Pakadali pano, kumwa "Actovegin" kuyimitsidwa ndipo wodwala wina amapatsidwa kwa wodwala, yemwe ali wofanana mu kapangidwe ka zinthu ndikupanga mankhwala omwe afotokozedwawo.

Kugwiritsa ntchito Actovegin kwa matenda ashuga komanso zovuta

Actovegin nthawi zambiri amatchulidwa ndi madokotala kwa odwala matenda ashuga. Njira zoterezi zimatsimikiziridwa kwathunthu, chifukwa mankhwalawa amakulolani kusintha momwe thupi limachitikira ndi shuga, kuchepetsa neuropathy. Mankhwalawa akulimbana ndi ululu m'miyendo, pomwe odwala amatha kuchita masewera olimbitsa thupi kwambiri. Mankhwalawa ali ndi phindu pa metabolism, amathandizira kuchiritsa mabala mwachangu. Chidachi chimabwezeretsa shuga.

Ngati shuga sakwanira mthupi, mankhwalawo amathandizira wodwalayo.

Type 2 shuga mellitus nthawi zambiri imayambitsa zovuta zingapo zomwe zimasokoneza magwiridwe antchito amunthu. Mankhwala Actovegin amathandizira kubwezeretsanso zochitika za ziwalo zomwe zakhudzidwa, kuchepetsa mwayi wokhala ndi stroke. Mankhwalawa amachepetsa magazi, amachepetsa maselo ndi mpweya, komanso amathandizira kufalikira kwa zotupa.

Chidziwitsocho chimaperekedwa kuti chizidziwitso chokha chokha ndipo sichingagwiritsidwe ntchito pakudzipangira nokha mankhwala. Osadzinyengerera, zitha kukhala zowopsa. Nthawi zonse funsani dokotala.Pofuna kukopera mwatsatanetsatane kapena mwatsatanetsatane zinthu zomwe zili pamalowo, kulumikizana kwofunikira kukufunika.

Mankhwala a antihypoxic Actovegin ndi zovuta zake zogwiritsidwa ntchito mu shuga

Ngakhale chitukuko cha matekinoloje azachipatala, kupezeka kwa mankhwala atsopano, matenda ashuga sanachiritsidwe kwathunthu ndipo amakhalabe vuto lofunika kwambiri kwa anthu.

Ziwerengero zikuwonetsa kuti anthu opitilira 2 biliyoni ali ndi matendawa, 90% ya iwo amadwala matenda a shuga a mtundu wachiwiri.

Kuphwanya kwa endocrine kotereku kumawonjezera chiopsezo cha mikwingwirima, mtima, komanso kufupikitsa moyo. Kuti azimva bwino, odwala amayenera kumwa mapiritsi a antihypertensive kapena kubayidwa insulin.

Actovegin yatsimikizira bwino matenda ashuga. Kodi chida ichi ndi chiyani komanso momwe chimagwirira ntchito, malamulo oyambira kugwiritsa ntchito - zonsezi tidzakambirana m'nkhaniyi.

Kodi Actovegin ndi chiyani?

Actovegin ndi kuchotsera komwe kumapezeka m'magazi a ng'ombe ndikudziyeretsa mapuloteni. Zimathandizira kukonza minofu: imachiritsa mabala pakhungu ndi kuwonongeka kwa nembanemba.

Zimakhudzanso kagayidwe ka ma cell. Zimathandizira kukonza kayendedwe ka okosijeni ndi glucose kumaselo.

Mitundu ya mankhwala Actovegin

Chifukwa cha izi, mphamvu zama cell zimachuluka, kuopsa kwa hypoxia kumachepa. Njira zoterezi ndizofunikira pakugwira ntchito kwamanjenje. Mankhwala amathandizanso poteteza magazi. Nthawi zambiri amalembera odwala matenda ashuga.

Mankhwalawa ali ndi ma nucleosides, amino acid, zinthu za phosphorous, magnesium, sodium, calcium, zopangidwa ndi lipid ndi carbohydrate metabolism. Izi zimathandizira kugwira ntchito yamtima, ubongo. Muzochita zachipatala Actovegin wagwiritsidwa ntchito kwa zaka zoposa 50 ndipo nthawi zonse amapereka zotsatira zabwino.

Kutulutsa Fomu

Pali mitundu yosiyanasiyana yotulutsira Actovegin:

• Mafuta 5%,
• mapiritsi
• 20% gel osakaniza akunja,
• jakisoni yankho
• 20% khungu lamaso
• 5% kirimu
• 0.9% yankho la kulowetsedwa.

Njira zothetsera mavuto ndi mapiritsi zimagwiritsidwa ntchito pochiza matenda ashuga. Yogwira pophika imatha hemoderivative.

Mapiritsi, imakhalapo pakukumana kwa 200 mg. Makapisozi amaikidwa m'matumba ndikuwakhazikitsa m'mabokosi amakhadi 10, 30, kapena 50. Zokomera ndi povidone K90, selulosi, magnesium yanthaka komanso talc.

Ampoules a jakisoni yankho la voliyumu ya 2, 5 kapena 10 ml ali ndi 40, 100 kapena 200 mg yogwira ntchito, motsatana. Zina mwa zinthu ndi sodium chloride, madzi osungunuka. Ampoules amagulitsidwa m'matumba a 5 kapena 25 zidutswa.

Mafuta onunkhira ndi mafuta ali ndi 2 mg ya hemoderivative, ndipo mu gel - 8 mg. Ma keloni, mafuta opangira mafuta ndi miyala yamtengo wapatali amadzaza mu chubu cha aluminiyumu chomwe chimakhala ndi 2030, 50 kapena 100 g.

Zokhudza matenda a shuga

Actovegin amachita ngati insulin pa munthu amene wapezeka ndi matenda a shuga a 2.

Izi zimatheka chifukwa cha kukhalapo kwa oligosaccharides. Zinthu izi zimayambiranso ntchito ya omwe amayendetsa shuga, omwe pali mitundu isanu. Mtundu uliwonse umafunikira njira inayake, yomwe mankhwalawa amapereka.

Actovegin imathandizira kayendedwe ka mamolekyu a glucose, imakhutitsa maselo amthupi ndi mpweya, imakhala ndi phindu pa kugwira ntchito kwa ubongo komanso mtima wamagazi.

Mankhwalawa amabwezeretsa shuga. Ngati mankhwalawa akuperewera, ndiye kuti mankhwalawo amathandizira kuti munthu akhale ndi thanzi, amasintha njira zolimbitsa thupi.

Kuphatikiza pa zochita za insulin, pali umboni wazomwe zotsatira za Actovegin pakukana insulin.

Mu 1991, kuyesako kunachitika komwe mitundu 10 ya matenda ashuga II idatenga nawo gawo. Actovegin pa mlingo wa 2000 mg amaperekedwa kwa anthu kwa masiku 10.

Pamapeto pa kafukufukuyu, zidapezeka kuti odwala amawona akukweza glucose ndi 85%, komanso kuchuluka kwa shuga. Kusintha uku kunapitilira maola 44 atatha kulowetsedwa.

The achire zotsatira za Actovegin zimatheka chifukwa chotere:

• kuchuluka kwa ma phosphates okhala ndi mphamvu zambiri,
• imapangitsa kaphatikizidwe wama protein ndi zakudya,
• Ma enzyme omwe amakhudzidwa ndi phosphorylation amathandizira,
• kusokonekera kwa shuga kwachitika mwachangu,
• Ma enzyme omwe amatulutsa sucrose ndi glucose amapangidwa mwachangu
• zochitika zama cell zimayenda bwino.

Phindu lopindulitsa la Actovegin pa shuga limadziwika ndi pafupifupi odwala onse omwe amagwiritsa ntchito mankhwalawa mankhwalawa. Malankhulidwe olakwika amachitika chifukwa chogwiritsa ntchito molakwika, hypersensitivity, ndi bongo wambiri.

Mlingo ndi bongo

Matenda a shuga amawopa mankhwalawa, ngati moto!

Ndikofunikira kutsatira.

Mlingo wa Actovegin zimatengera mtundu wa kumasulidwa, mtundu wa matenda ndi kuuma kwa njira yake.

M'masiku oyambilira, tikulimbikitsidwa kuperekera ndalama za intravenly poml. Ndiye kuchepetsa mlingo mpaka 5 ml patsiku.

Ngati infusions amagwiritsidwa ntchito, ndiye ml. Kwa jakisoni wa mu mnofu, muyezo waukulu ndi 5 ml.

Mu pachimake ischemic sitiroko, 2000 mg tsiku limasonyezedwa kudzera m`mitsempha. Kenako wodwalayo amasamutsidwa ku fomu ya piritsi ndikupatsidwa katatu makapisozi katatu patsiku.

Mlingo watsiku ndi tsiku wokhala ndi dementia ndi 2000 mg. Ngati kufalikira kwazungulira kumalephera, ndikulimbikitsidwa kugwiritsa ntchito mg tsiku lililonse. Anthu odwala matenda ashuga polyneuropathy amathandizidwa ndi mankhwala osokoneza bongo a 2000 mg patsiku kapena mapiritsi (3 zidutswa katatu patsiku).

Ndikofunika kuti musapitirire mlingo womwe umawonetsedwa mu malangizo ndi adokotala. Kupanda kutero, pamakhala chiopsezo chachikulu chodzakhala ndi mavuto. Kuti muchepetse zovuta zosasangalatsa zomwe zimachitika chifukwa cha bongo, mankhwala othandizira amasonyezedwa. Kwa ziwengo, corticosteroids kapena antihistamines amagwiritsidwa ntchito.

Malangizo ogwiritsira ntchito mankhwalawa

Kuphatikiza pa kuchiza matenda ashuga, Actovegin amagwiritsidwa ntchito ngati ischemic stroke, ngozi ya cerebrovascular, mitsempha ya varicose, kuvulala pamutu, zipsinjo zam'mimba komanso kuwotcha, komanso kuvulala kwa corneal.

Mankhwalawa amatha kuperekedwa pakamwa, mwaubwino komanso makamaka.

Actovegin mu mawonekedwe a piritsi ayenera kumwedwa theka la ola musanadye kapena maola angapo mutatha. Chifukwa chake, mayamwidwe okwanira a chigawo chogwira ntchito amapezeka ndipo chithandizo chamankhwala chimachitika msanga.

Ndikofunikira kutsatira mlingo. Kwa munthu wamkulu, malangizowo amalimbikitsa kugwiritsa ntchito mapiritsi a 1-2 patsiku. Ngati ndi kotheka, dokotala angasinthe mlingo wake. Kutalika kwa chithandizo kuchokera pa 1 mpaka 1.5 miyezi.

Ngati njira yothetsera jakisoni kapena kulowetsedwa yagwiritsidwa ntchito, iyenera kuperekedwa pang'onopang'ono, popeza mankhwalawa ali ndi vuto lothetsa chidwi. Ndikofunikira kuti kukakamizidwa kusapondereze kwambiri. Kutalika kwa maphunzirowa kumatsimikiziridwa payekha kwa wodwala aliyense.

Chithandizo cha kupsa, mabala ndi zilonda zam'mimba zimachitika pogwiritsa ntchito 20% Actovegin gel. Chilondacho chimatsukidwa ndi antiseptic. Gelalo limayikidwa mu wochepa thupi.

Pomwe amachiritsa, chilonda nthawi zambiri chimayamba kupanga. Kuti zitheke, gwiritsani ntchito kirimu 5% kapena mafuta. Ikani katatu patsiku mpaka kuchira kwathunthu. Gwiritsani ntchito mankhwala okhala ndi alumali.

Simungagwiritse ntchito yankho lomwe mumakhala timalingaliro tating'ono, mitambo. Izi zikusonyeza kuti mankhwalawa adachepa chifukwa chosasungidwa mosayenera. Ndi chithandizo cha nthawi yayitali, odwala matenda ashuga amalangizidwa kuti azilamulira bwino. Mukatsegula, vial kapena ampoule saloledwa.

Kuyanjana kwa mankhwala kwa Actovegin ndi mankhwala ena sikunakhazikitsidwe. Koma kuti mupewe kusagwirizana, simuyenera kuwonjezera mankhwala ena kulowetsedwa kapena jakisoni.

Zotsatira zoyipa

Actovegin amalekeredwa bwino. Nthawi zina, odwala amawona mawonekedwe oyipa:

• thupi lawo siligwirizana (mu mawonekedwe a anaphylactic mantha, malungo),
• myalgia
• redness khungu pakhungu,
• mapangidwe edema pakhungu,
• lacure, redness ya ziwiya za sclera (zamankhwala amaso),
• malungo
• kuyabwa, kuyaka m'dera la zolemba (zamafuta, miyala),
• hyperthermia
• urticaria.

Madokotala amazindikira kuti nthawi zina Actovegin alibe phindu pakukhudzidwa kwa mtima. Pankhaniyi, wodwalayo ali ndi kuchuluka kwa kuthamanga kwa magazi, kupumira msanga, kukomoka, kupweteka mutu, kufooka komanso kuperewera. Kuphwanya Mlingo wa mapiritsi, nseru, kumalimbikitsa kusanza, kupweteka m'mimba, kupweteka pamimba nthawi zina.

Actovegin a mtundu 2 matenda a shuga: kugwiritsa ntchito, chithandizo, ndemanga

Kwazaka makumi zapitazi, kuchuluka kwa anthu odwala matenda ashuga, makamaka mtundu wawo wachiwiri, kwawonjezeka. Mkhalidwewo umalumikizidwa ndikuwonongeka kwa zochitika zachuma mdziko lapansi, kunyalanyaza malamulo okhudzana ndi zakudya komanso nkhawa zomwe anthu amakumana nazo.

Matenda a shuga amachepetsa mphamvu ya mitsempha ya magazi athupi lonse, chifukwa chake chiopsezo cha kupangika kwa ma pathologies amomwe minofu imachokera. Matenda owopsa kwambiri a etiology awa amadziwika kuti ndi stroko komanso mtima.

Pakufunika kuwongolera kwathunthu kwa thupi la munthu ndikupanga chithandizo, poganizira mawonekedwe a matendawa. Actovegin ndi mankhwala omwe amathandizira kuthamanga kwa kagayidwe kazakudya ndi mpweya m'thupi. Zinthu zopangira mankhwalawa ndi magazi a ana a ng'ombe osakwanitsa miyezi isanu ndi itatu. Actovegin iyenera kugwiritsidwa ntchito, kutsatira mosamalitsa malangizo.

Kodi Actovegin ndi chiyani

Actovegin adagwiritsidwa ntchito kalekale mu zovuta zochiritsira zotsutsana ndi matenda a shuga ndi matenda ena a shuga. Mankhwalawa ndi gawo la gulu la mankhwala omwe amasintha kagayidwe kazomwe zimakhala ndi ziwalo.

Metabolism imakopeka pamaselo a cellular chifukwa cha kuchuluka kwa glucose ndi oxygen m'misempha.

Actovegin ndi kufalitsa kotsukidwa komwe kumachokera ku magazi a ng'ombe. Chifukwa cha kusefedwa kwabwino, mankhwalawa amapangidwa popanda zigawo zosafunikira. Kuyimitsidwa kumeneku kulibe zinthu zomanga thupi.

Mankhwalawa ali ndi zinthu zingapo za kufufuza, amino acid ndi ma nucleoside. Ilinso ndi zapakatikati zopanga lipid ndi carbohydrate metabolism. Zinthu izi zimatulutsa mamolekyulu a ATP pakuchita.

Zofunikira zomwe mankhwalawa amapezeka ndi monga:

Zidazi zimakhudzidwa ndikuonetsetsa kuti ubongo ukugwira ntchito mwanzeru, komanso mtima. Mankhwalawa alibe zinthu zomwe zingayambitse thupi lawo.

Kugwiritsa ntchito Actovegin kwakhala kukuchitika kwa zaka zoposa 50, ndipo chida sichikutaya kutchuka kwake. Mankhwala amathandizira kagayidwe kazakudya mu zimakhala, zomwe zimatheka chifukwa:

1. kuchuluka kwa ma phosphates omwe ali ndi mphamvu zambiri,
2. activating michere nawo phosphorylation,
3. kuchuluka kwa maselo,
4. onjezani kupanga mapuloteni ndi chakudya chamafuta m'thupi,
5. kuwonjezera kuchuluka kwa shuga mkati mwa thupi,
6. zomwe zimayambitsa makina opanga ma enzyme omwe akuphwanya sucrose, shuga.

Chifukwa cha malo ake, Actovegin amadziwika kuti ndi amodzi mwa mankhwala osokoneza bongo abwino kwambiri amtundu wachiwiri wa matenda a shuga. Makamaka, ili ndi zabwino izi:

• amachepetsa neuropathy
• imapereka malingaliro abwinobwino pa shuga,
• amachotsa ululu m'miyendo ndi manja, zomwe zimapangitsa munthu kuti azichita momasuka,
• amachepetsa kugona,
• bwino minofu kusinthika,
• imayendetsa kusinthana kwa mphamvu zamagetsi ndi zina zofunikira.

Actovegin ndi zovuta za matenda ashuga

Mu shuga mellitus, anthu nthawi zambiri amakhala ndi zovuta zosiyanasiyana zomwe mankhwalawa amapirira. Kugwiritsidwa ntchito kwa Actovegin kudzera m'mitsempha kumapangitsa kuti njira zothamangira mabala azichiritse ndikubwezeretsa ntchito za ziwalo.

Chidacho chimathandizanso kuchepetsa vuto la stroke. Mothandizidwa ndi Actovegin, kuchuluka kwa kukhathamira kwa magazi kumachepa, maselo amakhala ndi mpweya, ndipo kupita patsogolo kwa zovuta kumakhala kochepa.

Actovegin amagwiritsidwanso ntchito ngati munthu akukumana ndi ziphuphu. Actovegin adayikidwa ndi dokotala wokhazikika atapima thupi mozama ndikuchita mayeso ofunikira.

Njira yakuchiritsira imayenera kuganizira mawonekedwe a thupi la wodwalayo.

Iyenera kuwunikiridwa makamaka kuti athe kulolera ku zinthu zina za chinthucho pofuna kupewa zovuta.

Malangizo ogwiritsira ntchito mankhwalawa

Mankhwala Actovegin akhoza kuperekedwa pakamwa, toply ndi kholo. Njira yotsiriza ya kayendetsedwe kake ndiyothandiza kwambiri. Komanso, mankhwalawa amatha kuperekedwa kudzera mu kukhuthala kwamitsempha. 10, 20 kapena 50 ml ya mankhwalawa ayenera kuchepetsedwa ndi shuga kapena mchere.

Njira ya mankhwalawa imaphatikizapo 20 infusions. Nthawi zina, mankhwalawa amatchulidwa mapiritsi atatu katatu patsiku. Actovegin amayenera kutsukidwa ndi madzi pang'ono oyera. Pomwepa, mankhwalawo amagwiritsidwa ntchito ngati mafuta kapena mafuta ngati gel.

Mafuta amagwiritsidwa ntchito ngati mankhwala ochiritsa kapena mabala. Pochiza zilonda zam'mimba m'matumbo a shuga, mafuta amtopowo amapaka pazidutswa. Dera lomwe lakhudzidwalo limakutidwa ndi bandeji kwa masiku angapo. Zilonda zonyowa, kuvala kumayenera kusinthidwa tsiku lililonse.

Malinga ndi malangizo, Actovegin a shuga mellitus amtundu wachiwiri ndi omwe amaperekedwa ngati pali:

1. kuvulala kumutu kwakanthawi
2. zovuta chifukwa cha matenda a ischemic,
3. mawu amachepetsa,
4. kuphwanya zakudya ndi khungu.
5. zilonda zosiyanasiyana
6. khungu lakufa ndikuwotcha.

Chitetezo

Mankhwalawa amapangidwa ndi kampani ya Nycomed, yomwe imapereka chitsimikizo cha chitetezo cha mankhwalawa. Mankhwalawa sayambitsa zovuta zowopsa. Mankhwala amapangidwa kuchokera ku magazi a nyama omwe amachokera ku mayiko omwe ali otetezeka ku matenda ndi matenda a chiwewe.

Zida zowonongeka zimayang'aniridwa mosamala mogwirizana ndi malamulo apadziko lonse lapansi. Ng'ombe zimaperekedwa kuchokera ku Australia. WHO imazindikira kuti Australia ndi dziko lomwe mulibe mliri wa spongiform encephalopathy mwa nyama izi.

Tekinoloje yopanga mankhwalawa cholinga chake ndikuchotsa othandizira.

Kwazaka zambiri, mankhwala akhala akugwiritsa ntchito mankhwalawa;

Analogs ndi mtengo wa mankhwalawo

Actovegin amagulitsidwa mumitundu yokwana 109 mpaka 2150 rubles. Mtengo umatengera mtundu wa mankhwalawa amasulidwe. Chimodzi mwazodziwika za Actovegin ndi mankhwala a Solcoseryl. Mankhwalawa amapangidwa mu mawonekedwe a mafuta, mafuta ndi njira za jakisoni.

Ubwino wa chida ichi ndi pafupifupi kudziwa kwathunthu ndi Actovegin. Mankhwala ali ndi yogwira - dialysate, yoyeretsedwa kuchokera ku mapuloteni. Zinthu zimapezekanso ndi magazi a ana ang'onoang'ono.

Solcoseryl amagwiritsidwa ntchito pochiza matenda omwe amayamba chifukwa cha kusowa kwa oxygen m'maselo, komanso pochiritsa kupsa ndi mabala azosiyanasiyana. Kuvomerezedwa ndikosayenera panthawi ya kubereka ndi kuyamwitsa. Mtengo wa mankhwalawa umachokera ku ruble 250 mpaka 800.

Dipyridamole ndi Curantil zimathandizira magazi ndipo amatha kukhala analogue Actovegin pa matenda a zotumphukira zamitsempha. Mtengo wa mankhwalawa umayambira ma ruble 700.

Monga gawo la Curantil 25, chinthu chachikulu ndi dipyridamole. Mankhwalawa amapatsidwa mankhwala ochizira matenda osiyanasiyana a thrombosis, amathandizanso kukonzanso pambuyo poti myocardial infarction. Chidachi ndi choyenera pa analogi ya Actovegin.

Curantyl 25 imapezeka mu mawonekedwe a dragees, mapiritsi kapena jakisoni. Mankhwalawa amatsutsana kwambiri pamatenda owopsa a mtima, zilonda zam'mimba, matenda oopsa, matenda a impso ndi chiwindi, pakati komanso chidwi chachikulu cha chinthu chachikulu. Mtengo wapakati ndi ma ruble 700.

Mapiritsi a Vero-trimetazidine amagwiritsidwa ntchito pochiza matenda a ischemia. Ali ndi mtengo wotsika mtengo kwambiri, mtengo wake ndi ma ruble 50-70 okha.

Cerebrolysin ndi mankhwala osokoneza bongo omwe ndi mankhwalawa a nootropic ndipo amagwiritsidwa ntchito ngati analogue ya Actovegin pang'onopang'ono chifukwa cha kusokonekera kwa dongosolo lamkati lamanjenje. Mtengo wa cerebrolysin ndi wochokera ku 900 mpaka 1100 rubles. Mankhwala Cortexin amathandizira kukonza metabolism yaubongo, mtengo wake, pafupifupi, ndi ma ruble 750.

Mitundu yosiyanasiyana yofananira yopanga yaku Russia ndi yakunja imapangitsa kusankha analogi yoyenera komanso yapamwamba ku Actovegin.

Nootropil ndi mankhwala omwe amagwiritsidwa ntchito kwambiri ngati mankhwala. Chofunikira chake chachikulu ndi piracetam. Nootropil imawoneka ngati analogue yapamwamba kwambiri ya Actovegin. Amamasulidwa mu mawonekedwe a:

1. jakisoni njira
2. mapiritsi
3. madzi a ana.

Nootropil imayendetsa bwino ndikubwezeretsa kugwira ntchito kwathunthu kwa ubongo wa munthu. Mankhwalawa amagwiritsidwa ntchito pochiza matenda osiyanasiyana amanjenje, makamaka matenda amisala. Chida ichi chili ndi zotsutsana zotsatirazi:

• yoyamwitsa
• mimba
• kulephera kwa chiwindi
• magazi
• Hypersensitivity kuti piracetam.

Mtengo wapakati wa mankhwalawo uli pamtunda kuchokera ku 250 mpaka 350 rubles.

Zambiri zomaliza

Actovegin ndi mankhwala othandiza kuchiza matenda ashuga omwe ali m'magawo akulu matendawa. Pogwiritsa ntchito moyenera ndikutsatira malingaliro a dokotala, mankhwalawa ali otetezeka kwathunthu kwa thupi.

Chifukwa cha Actovegin, mayendedwe a glucose amayenda mwachangu. Gawo lililonse la thupi limatha kumaliza bwino zinthu zofunika. Zotsatira za kafukufuku wamankhwala zimati zotsatira zoyambirira zogwiritsa ntchito mankhwalawa zimabweranso sabata lachiwiri la mankhwala.

Actovegin pa matenda a minyewa mavuto a shuga

Wolemba mu magazine:

Ph.D. I.A. Ma Rows 1, K.I. Mizere 2, MD, prof. A.S. Ametov 2
1 Choyamba MGMU iwo. I.M.Sechenova
2 RMAPO

Kugonjetsedwa kwa zotumphukira ndi ma system amanjenje kumawonedwa, makamaka ndi kusokonezeka kwakutali kwa matenda a carbohydrate metabolism, mwa odwala ambiri omwe ali ndi matenda osokoneza bongo a mellitus (DM) 1, 2. Matenda a Metabolic omwe amayamba chifukwa cha kupsinjika kwa oxidative, komanso kuchepa kwa magazi m'magazi a microscirculation chifukwa cha endothelial kuwonongeka komwe kumayenderana ndi matenda a metabolic. ndi mtima khoma, kumabweretsa phenomena wa ischemia ndi hypoxia mu minyewa yamanjenje. Mavuto amachedwa a mitsempha am'mbuyo amakhala chifukwa chomawonjezera kuchepa kwamatenda, mavuto a kulumala komanso kusintha magwiridwe antchito kwa odwala matenda ashuga.

Wasayansi P. J. Dyck adawonetsa kuti pali kulumikizana pakati pa kuchuluka kwa minyewa yam'mitsempha ya m'mitsempha ya m'mitsempha ndi makulidwe a khoma la zotengera za kumapeto kwa shuga. Chifukwa chake, mbali ya mtima ndi imodzi yomwe imatsogolera pakupanga matenda ashuga a distal symmetric sensory-motor polyneuropathy (DPN). Njira za chitukuko cha matenda ashuga encephalopathy zimaphatikizidwanso ndi kusokonezeka kwa metabolic komanso yachiwiri ya mtima wam'magazi, ndipo pamenepa sikuti kuwonongeka kwa ma cellcirculattery ndizofunikira, komanso chitukuko chifukwa cha zotupa zoyambirira za atherosulinotic zamavuto amtsempha wamagazi m'mitsempha yayikulu ya chithokomiro 4, 5. Kulamulira bwino kwa glycemic mu odwala matenda ashuga ogwiritsira ntchito mankhwala a insulin othandizira pazifukwa izi angachepetse chiopsezo chotenga DPN kwa odwala omwe ali ndi matenda amtundu wa 1, koma samakhudza kwambiri chitukuko cha DPN mwa odwala omwe ali ndi matenda a shuga 2 lembani 6, 7.Pankhani imeneyi, sitikukayikira kufunikira kochizira matenda am'mbuyomu omwe ali ndi vuto la shuga kuti athe kusintha mkhalidwe wa odwala komanso kupewa kuthamanga kwa DPN ndi matenda ashuga a shuga. Mankhwala othandizira pathogenetic odwala omwe ali ndi zovuta za matenda a shuga, kukonzekera kwa antioxidant ndi thiamine kumagwiritsidwa ntchito, omwe, mwa kusintha kagayidwe kachakudya kagayidwe ka magazi, magazi amatuluka m'magazi a ma cellcirculation 8, 9, 10. Cholinga cha mankhwalawa ndichachikhalidwe cha mankhwala amakono ndipo amadziwa zambiri pakugwiritsa ntchito kwawo ndi DPN. Njira zothandizira odwala matenda ashuga a encephalopathy zakhala zikufufuzidwa pang'ono.

M'zaka zaposachedwa, kugwiritsa ntchito Actovegin pochiza matenda am'mbuyomu kwakhala ndichisangalalo kwambiri. Mankhwala amatha kusintha magwiridwe antchito ya zotumphukira ndi chapakati mantha, kuchepetsa zovuta oxidative nkhawa, ma cell ndi hypulin. Makina ochita Actovegin mwa odwala omwe ali ndi matenda amitsempha osiyanasiyana adawunikanso ndemanga zingapo 11, 12. Zimadziwika kuchokera ku kafukufuku woyeserera kuti zotsatira za Actovegin pa glucose metabolism zimayamba mphindi 5 pambuyo pakukonzekera kwamkati mwa mankhwalawa ndikuwonjezereka kwa kanthu atapezeka pambuyo pa mphindi 120. Poyeserera nyama, zimawonetsedwa kuti Actovegin ali ndi zochitika ngati insulin. Actovegin imathandizira kuonjezera kuchuluka kwa njira za redox mu hepatocytes, amachepetsa kuwonongeka kwa ma cell komanso ntchito kwa mitochondria ya cardiomyocyte, ndikuwonjezera kuchepa kwa glucose kagayidwe kosalekeza. Kupititsa patsogolo mphamvu ya ma cell a ziwalo zosiyanasiyana komanso ma minofu, kuphatikiza dongosolo lamanjenje, zimalumikizidwa ndi kuthekera kwa mankhwalawa kusintha shuga m'magazi potumiza otulutsa ake (GluT) ndi zochita za insulin monga zigawo zikuluzikulu za mankhwala - inositol phosphooligosaccharides. Chifukwa chakuti Actovegin modulates glucose intracellular glucose, lipolysis imayendetsedwa. Kuthekera kwa kugwiritsa ntchito Actovegin pochiza matenda ashuga ndi metabolic syndrome 15, 16. Kuyang'anira munthawi yomweyo kwa β-blocker (bisoprolol) ndi Actovegin kumabweretsa kuwonjezeka kwa matenda a ubongo m'magazi a metabolic syndrome. Mphamvu ya antihypoxic ya Actovegin imachitika chifukwa chakuti imalimbikitsa kuyamwa kwa okosijeni ndi zimakhala, zomwe zimawonjezera kukana kwa maselo ku hypoxemia. Kupereka kwa oksijeni ku minofu kumapangitsa kuti ma macroergic phosphates (ATP, ADP) amachepetsa mphamvu. Chifukwa chopeza bwino mpweya wabwino ndi mtima khoma ndi kukhazikitsidwa kwa Actovegin, endothelium-zimadalira zochita zimasintha ndi zotumphukira mtima kukana amachepetsa. Mphamvu ya antioxidant ya Actovegin imaperekedwa ndi kukhalapo kwa mkuwa, kuyambitsa superoxide dismutase, komanso ma magnesium ions popanga mankhwala, omwe amalimbikitsa ntchito ya glutathione synthetase, yomwe imamasulira glutathione kukhala glutamine. Posachedwa, Actovegin yatsimikiziridwa kuti itenga mlingo-wodalirika kuchepetsa oxidative nkhawa-inachititsa hydroxy-oxide mu neuronal cell chikhalidwe cha M. W. Elminger, posindikiza. Maphunziro ambiri adachitika kuti athe kuwunika momwe Actovegin a DPN 19, 20, 21, omwe amakonzedweratu ndi machitidwe amomwe amapangira mankhwala. Malinga ndi zomwe zikupezeka pakadali pano, kukula kwa DPN kumalumikizidwa ndi kupsinjika kwa glucose metabolism, komanso kufooka kwamankhwala enieni a antioxidant 3, 22. Munthu angavomerezenso malingaliro akuti "matenda ashuga amayamba, ngati matenda osinthana, ndipo amatha ngati matenda amitsempha yam'mimba" . Matenda a metabolism, omwe amachititsa kusintha kwa phosphate mphamvu yamagawo mu cytoplasm of cell, kumabweretsa kukula kwa chodabwitsa cha "pseudohypoxia".Kutsekeka kwa khoma lamitsempha yama chotupa cham'mimba ndikusintha kwa masinthidwe amtundu wamagazi m'magazi a shuga kumayambitsa kukula kwa hypoxia yoona. Lingaliro ili la metabolic ndi minyewa yomwe imayambitsa chitukuko cha DPN imapangitsa kukhala koyenera kugwiritsa ntchito Actovegin pochiza DPN, yomwe imatha kuwongolera njira za hypoxia ndi glucose metabolism.

Mkuyu. 1. Njira za achire zochita za Actovegin

Pakufufuza kochokera kwa W. Jansen ndi E. Beck, odwala omwe ali mgulu lachipatala la Actovegin adachita bwino odwala ambiri masabata 8 atayamba chithandizo, ndipo zotsatira zoyenera zimatheka pambuyo pa milungu 16 ya chithandizo. Kusintha kwakukulu kunawonetsedwa pa chithandizo cha Actovegin poyerekeza ndi gulu la placebo pafupifupi zofunikira zonse zamankhwala: kuyenda mtunda wopanda ululu, tendon Reflex, chidwi kopitilira muyeso (p. Mu ntchito ya V.A. Yavorskaya et al., Actovegin adagwiritsidwa ntchito pochita kafukufuku wotseguka kuchitira DPN mu Odwala a 24 omwe ali ndi matenda amtundu wa 1 komanso a 2 mtundu wa infusions wa tsiku lililonse kwa masiku 20, ntchito zamankhwala, zofufuza zamitsempha yamagazi, ndi mayeso a EMG ndizo zinali zothandiza. kuwongolera kwakukulu mu kachipatala komwe odwala akudwala m'njira yochepetsera kupweteka, kuchuluka kwa chidwi ndi kupweteka kwa tendon, kuchuluka kwamphamvu kwa minofu.Reovasography ikuwonetsa kusintha kwa magazi m'miyendo, ndipo kufufuza kwa EMG kumawonjezera matalikidwe a M-yankho ndi SRV pa kukondoweza kwa mitsempha yamiyendo. ndi matenda amishuga am'magazi a kusiyanasiyana malinga ndi gulu la Wagner adawonetsa kuti kuwonjezeranso mankhwalawa ku mankhwala achikhalidwe kunathandizira kupweteka msanga Zokhudza matendawa komanso kuthamanga kwa njira za granulation ndi epithelization wa zilonda zam'mimba ndi machiritso awo. Mu kafukufuku omwe adafotokozedwa ndi F.E. Morgoeva et al, kuthandizira kwamankhwala ogwiritsidwa ntchito molimba ndi Actovegin mwa odwala omwe ali ndi matenda a shuga a 2 adaphunzira. Gulu la odwala 30 omwe adalandira Actovegin kamodzi patsiku kwa masabata atatu (infusions 15) mwanjira ya 400 mg, kuchepetsedwa mu 200.0 ml ya saline yanyama, kuphatikiza odwala omwe ali ndi matenda osokoneza bongo osachepera zaka 10 ali ndi zaka 58.94 Years Zaka 1.29 (amuna 9 ndi akazi 21). Kupezeka kwa DPN kudakhazikitsidwa pamaziko a kuyesa kwa mitsempha, zotsatira za EMG, kuchuluka kwa sensory komanso kudziyesa pawokha. Gululi lidaphatikizapo odwala omwe anali ndi magawo a 2a ndi 2b a DPN malinga ndi gulu la P. J. Dyck ndi HbA1 C osaposa 10%. Kuunika kwa zabwino za ma neuropathic zizindikiro (kusapeza bwino kwa wodwala) kunachitika pogwiritsa ntchito kuchuluka kwa TSS (Total Syndromeom Score), ndikusanthula kwakuthwa kwa kupweteka, kuwotcha, dzanzi komanso paresthesia. Zizindikiro zoyipa za neuropathic (kuchepa kwa mitsempha) zinayesedwa pamlingo wa NIS LL (Neuropathy Imiguement Score Limb Limb - alama ya kusokonezeka kwa mitsempha ya miyendo) poyesa mphamvu zam'mitsempha, kuwunikira komanso kumva zosiyanasiyana. Kafukufuku wokhudzana ndi magwiridwe antchito am'mapapo am'm miyendo anachitika ndi njira yolimbikitsira EMG poyeserera mitsempha ya motor (n.peroneus) ndi sensory (n.suralis). Kuwunika kambiri pamtunda ndi chidwi chachikulu, komanso kudziyang'anira ndi mtima wokha kunachitika pa chipangizo cha CASE-IV (Medical Electronics, USA) ndi kutsimikiza kwa kuzizira kwa kuzizira, kupweteka kwa kutentha ndi kugunda kwamphamvu. Mlingo wa oxidative nkhawa unaweruzidwa ndi zomwe malondialdehyde m'magazi seramu ndi erythrocyte hemolysate. Mkhalidwe wa ma microcirculation udawerengeredwa pa kama wamatumbo a chala chachiwiri pa kompyuta capillaroscope GY-0.04 kuchokera ku Center for the Analysis of Subinto (Russia). Kusanthula kwa zithunzi za digito kunapangitsa kuti azindikire kuthamanga kwa magazi, kuchuluka kwa "sludge phenomena", ndi kukula kwa edema yamkati.Kuyesedwa kwa odwala kunachitika isanachitike komanso atamaliza maphunziro ndi Actovegin. Asanalandire chithandizo, pagulu la odwala matenda a shuga omwe ali ndi DPN, kuwonjezeka kwakukulu kwa lipid peroxidation mu plasma ndi erythrocyte membranes kunadziwika poyerekeza ndi gulu la odzipereka 15 athanzi la m'badwo womwewo, omwe adawonetsa kuzunzika kwa oxidative nkhawa. Chithandizo cha Actovegin chinapangitsa kutsika kwa malondialdehyde mu plasma ndi erythrocyte nembanemba ndi mawonekedwe ake. Chifukwa chake, Actovegin anali ndi zokayikitsa za antioxidant, pogwiritsira ntchito njira za pathogenetic za kukula kwa DPN. Mkhalidwe wamagazi omwe amapezeka m'magazi amayesedwa ndi kompyuta capillaroscopy asanafike mankhwala ndi Actovegin. Pambuyo pochiza ndi Actovegin, kusintha kwakukulu mu mawonekedwe apamwamba a magazi a capillary kunadziwika, osangowonetsa zochitika za magazi, komanso mkhalidwe wololeza kwa khoma la capillary.

Kuopsa kwa zizindikiro za neuropathic musanalandire chithandizo pamankhwala a TSS kunali kofunikira (mfundo za 7.79). Pambuyo pa chithandizo, panali kuchepa kwakukulu pamiyezo yonse ya kuchuluka kwa TSS komanso kuchuluka kwa chimodzi mwazizindikiro zamalingaliro mosiyana (p Mu 2009, zotsatira za kafukufuku wamitundu yambiri, zokhala ndi khungu lachiwiri, zodziwidwa ndi placebo zothandizira odwala omwe ali ndi matenda amtundu wa 2 omwe ali ndi DPN zidafotokozedwa. mu phunziroli, panali zizindikiro zabwino za neuropathic, zomwe zimayesedwa pamlingo wa TSS, ndi gawo lanthete yolumikizira mphamvu, yomwe idayesedwa pamalo angapo pamiyendo ah (ankle, zala zam'manja) pogwiritsa ntchito biotensiometer. Njira zoyendetsera ntchito za sekondale zidasankhidwa kukhala ziwonetsero za kukula kwa TSS, kuchuluka kwa NIS-LL ndi mawonekedwe amitundu ya moyo (chidule zolembedwa mokhudzana ndi zabwino za ma neuropathic, komanso kuwongolera kunadziwika m'mbali zonse za zizindikiro zonse, komanso pokhudzana ndi chizindikiro chilichonse (tebulo. 1, mkuyu. 2). Kuchepa kwakukulu kwa kuchepa kwa mitsempha yam'maso kunawululidwa, mokhudzana ndi kusintha kwa Reflex ndi mphamvu ya minofu, panali malingaliro abwino otukuka, osafika pamlingo wina wodalirika. Mwinanso izi zimachitika chifukwa chakuti mawonekedwe am'mimba ndipo makamaka mphamvu zam'mimba adasinthidwa ochepa odwala. Zizindikiro zakutsogolo za dziko la ulusi wamitsempha yamagetsi zimayesedwa poyesa kudziwa kuzungulira kwa kugunda kwamphamvu. Kuchepa kwa mphindikati kwa kugunda kwa chidziwitso kunali kofunikira pakugwiritsa ntchito Actovegin poyerekeza ndi placebo. Phunziroli ponseponse, glucose yofulumira komanso chizindikiro chokwanira cha miyezi iwiri ya matenda ashuga (HbA1 c) adatsimikiza. Zotsatira zomwe zapezedwa zikuwonetsa kuti mphamvu ya Actovegin imagwirizanitsidwa ndi zomwe zimachitika ndi mankhwalawo, osati kusintha kosintha kwa matenda ashuga. Palibe zochitika zowopsa zomwe zidawoneka phunziroli.

Gome 1. Kusintha kwa zizindikiro zazikulu kumapeto kwa kafukufuku

Makanema okhudzana nawo

About limagwirira a ntchito mankhwala Actovegin mu kanema:

Chifukwa chake, Actovegin ndi mankhwala othandiza kuchiza matenda a shuga a mitundu yoyamba ndi yachiwiri, komanso zovuta za matendawa. Ngati mugwiritsa ntchito mankhwalawa molondola, kutsatira malangizo a dokotala-endocrinologist, kuganizira mawonekedwe a thupi, ndiye kuti Actovegin idzakhala bwino ndipo sichidzayambitsa mikwingwirima.

• Imakhazikika pamisempha ya shuga kwa nthawi yayitali
• Imabwezeretsa kapangidwe ka insulin

Actovegin a 2 mtundu wa mellitus wa shuga: zikuonetsa, malamulo ogwiritsira ntchito

Ngakhale chitukuko cha gawo lazachipatala, matenda ashuga akadali amodzi mwa zovuta zomwe anthu ambiri amakumana nazo.Malinga ndi kafukufuku, pafupifupi anthu mabiliyoni a 0.2 akudwala matendawa, 90% ya iwo omwe amakhudzidwa ndi matenda a shuga a 2.

Matendawa amawonjezera mwayi wokhala ndi vuto la mtima, mikwingwirima, chifukwa chake, madokotala akuwonetsa mankhwala othandizira odwala omwe ali ndi mankhwala apadera, omwe amafanana ndi machitidwe a ziwalo zamkati.

Actovegin a matenda ashuga a 2 adziwonetsa okha kumbali yabwino.

Zambiri

Actovegin amatanthauza mankhwala omwe ntchito yake yayikulu ndikulimbitsa metabolism. Maziko ndi kufalikira kwa magazi a ng'ombe ya ng'ombe. Thupi limayeretsedwa kwathunthu kuphatikizidwa kwama protein ambiri. Kuphatikizikako ndikuphatikiza kuchuluka kwa ma amino acid othandiza, kufufuza zinthu, ma nucleoside, chakudya, zida za lipid.

Njira yogawa zinthuzi imakupatsani mwayi wogawa mphamvu zambiri, ndizofunikira kwambiri kwa maselo a wodwala yemwe ali ndi matenda a mtundu 2.

Actovegin mulinso sodium, magnesium, calcium, phosphorous. Zinthu zam'mimba zimakupatsani mwayi wokhudzana ndi kayendedwe ka mtima, kugwira ntchito kwa ubongo. Kuphatikiza pa chilichonse, mankhwalawa alibe zinthu zomwe zingayambitse ziwengo.

Pharmacological ikufuna kukonza kufalikira kwa magazi m'matumbo amthupi, kupereka minofu ndi ziwalo ndi mphamvu yofunikira pamaselo, kubwezeretsa ntchito zogwiranso ntchito, kukonza mkhalidwe wamaganizidwe a wodwala yemwe ali ndi matenda a shuga a mtundu wachiwiri.

Mankhwalawa amapita limodzi ndi mankhwala ena a insulin. Ndi chithandizo chake, mphamvu ya chithandizo imachulukitsidwa kangapo, komwe amafotokozedwa ndi kuthekera kwa maselo kusinthana michere yambiri.

Mtundu wamankhwala

Monga lamulo, mankhwalawa amapezeka mwanjira zotsatirazi:

• ngati mapiritsi
• njira zothetsera zamkati,
• mayankho a otsikira,
• mafuta, gel, kirimu ndi ena othandiza kunja.

Malinga ndi malangizo, piritsi lililonse lili ndi pafupifupi 200 mg ya chinthu chomwazika m'magazi a ng'ombe. Ponena za mayankho a jakisoni, 1 mg ya mankhwalawa ili ndi 0,4 mg yogwira ntchito. Zinthu zocheperako zimakhala ndi mayankho omwe amagwiritsidwa ntchito pokoka madontho - pafupifupi 10-20% pa mg.

Mapindu ake

Chifukwa cha mawonekedwe achilengedwe, Actovegin imadziwika kuti ndi imodzi mwazithandizo zabwino kwambiri za matenda a shuga. Amakhala ndi zotsatirazi:

• Amapereka zimachitika kuti thupi limachita bwino ndi shuga,
• amachepetsa neuropathy
• Amachepetsa ululu m'mikono ndi m'miyendo, zomwe zimathandiza kuti odwala azikhala ndi nkhawa kwambiri miyendo,
• amachotsa kumverera kwadzuwa,
• bwino kagayidwe kazakudya, michere,
• imathandizira kuchiritsa.

Werengani komanso Kudzimbidwa komanso kugwiritsa ntchito mankhwala oletsa bongo m'matenda a 2 shuga.

Zokhudza matenda a shuga

Actovegin amachita munthu wodwala matenda ashuga a 2, ofanana ndi mphamvu ya insulin. Izi ndichifukwa cha kukhalapo kwa oligosaccharides. Amayambiranso magwiridwe antchito a shuga, omwe alipo mitundu isanu. Aliyense amafunikira njira yake, yomwe imatsimikiziridwa ndi mankhwalawa.

Mankhwalawa amathandizira kuyenda kwa mamolekyulu a shuga, amalimbitsa maselo ndi mpweya, amathandizanso pakugwira ntchito kwa ubongo, komanso pakuyenda kwa magazi m'mitsempha yamagazi. Mankhwala amakulolani kubwezeretsanso glucose, ndipo ngati sikokwanira, kumathandizira kukhalanso ndi thanzi la munthu, zochitika zamagulu olimbitsa thupi pamlingo woyenera.

Zotsatira pa Mavuto

Mu matenda a shuga, odwala nthawi zambiri amakhala ndi zovuta zambiri, zomwe mankhwalawa amathana nawo bwino. Kugwiritsira ntchito mankhwalawa kumakulolani kuti mufulumize kuchira, kubwezeretsa ntchito za ziwalo.Actovegin amachepetsa chiopsezo cha stroke. Amachepetsa kuchuluka kwa magazi, ndikukonzekeretsa maselo amthupi ndi okosijeni, ndikuchepetsa kufalikira kwa chilondacho.

Malinga ndi malangizo, Actovegin yochizira matenda amishuga 2 amadziwika ngati pali:

• kusakwanira kwa magazi kuubongo, zovuta zamagazi,
• mavuto pambuyo pa ischemic sitiroko,
• kuvulala kumutu kwapita
• mavuto ndi mtima kamvekedwe,
• kuphwanya mkhalidwe ndi zakudya za pakhungu,
• Zilonda zamtundu uliwonse
• necrosis yamadera osiyanasiyana khungu, amayaka.

Mankhwalawa amagwiritsidwa ntchito pamavuto amaso, makamaka, ndi ziphuphu. Komabe, musamadziderere.

Actovegin ndi okhawo omwe amapezeka pambuyo poti adayeza thupi lonse, ndikuwunikira koyenera. Pulogalamu yamachiritso ya mankhwala osokoneza bongo iyenera kuganizira mawonekedwe a munthu.

Mwapadera amalipirira kusalolera thupi la munthu zigawo zikuluzikulu za mankhwala, kupewa mavuto.

Zotsatira zoyipa ndi zotsatira za ntchito

Kutengera ndi malangizo, pulogalamu ya chithandizo yochotseredwa ndi dokotala wokhala ndi matenda amtundu wa 2, Actovegin sikuti imakhudza thupi, samayambitsa zosayembekezereka.

Werengani komanso momwe Mungapewere kukula kwa matenda ashuga

Kuphatikiza apo, chithandizo chamankhwala chimaganizira kuchuluka kwa kuzindikira kwa mankhwala, chifukwa chake, ndi tsankho la munthu payekha pazinthu zomwe zimakhala maziko, dokotala woyenerera sangaphatikizidwe ndi mankhwalawa mu pulogalamu ya chithandizo.

Ngakhale izi, zitsanzo zimadziwika mchitidwewu kugwiritsa ntchito mankhwalawa chifukwa cha chifuwa, edema, kutentha thupi, komanso kutentha thupi.

Actovegin nthawi zambiri samatha kuyipitsa chikhalidwe cha mtima. Izi zikuwonetsedwa ndi kuthamanga kwa magazi, kupumira msanga, kupweteka pamtima, thanzi lofooka, chizungulire.

Ndizothekanso kupezeka kwa ululu m'mutu kapena kuwonongeka.

Ndi ntchito yamkati, ngati Mlingo wasokonezeka, kupweteka kwam'mimba, mseru ndi kusanza zitha kuoneka.

Mwambiri, mankhwalawa ndi chida chothandiza polimbana ndi matenda ashuga. Izi zikufotokozera momwe madokotala ambiri amagwiritsira ntchito. Zotsatira zakuchokera kunja kwa mankhwalawa zimadziwulula mwachangu kwambiri - pafupifupi patangotha ​​nthawi yochepa.

Ngati nthawi ya chithandizo, wodwalayo akumva kupweteka m'malo osiyanasiyana a thupi, pali kuwonongeka m'moyo wabwino, ndikulimbikitsidwa kuti mupitirize kuonana ndi dokotala. Ithandizanso kudziwa zomwe zimayambitsa izi mthupi, kusintha mankhwala omwe amagwiritsidwa ntchito ndi mankhwala ofananawo.

Kuphwanya kwakukulu

Mankhwalawa amaletsedwa kotheratu kwa ana osaposa zaka zitatu ndi anthu omwe ali ndi chidwi chachikulu ndi zigawo za Actovegin.

Osagwiritsa ntchito azimayi omwe ali ndi matenda ashuga panthawi yokhala ndi pakati. Kugwiritsa ntchito mankhwalawo ndizoletsedwa kwa amayi achichepere omwe m'mbuyomu anali ndi vuto lokhala ndi pakati (zolakwika, kusakhazikika kwa mwana wosabadwayo), kusakwanira kwa placental.

Ndikulimbikitsidwa kuti musagwiritsidwe ntchito kwa anthu omwe ali ndi vuto la m'mapapo omwe ali ndi vuto la kusowa kwa mpweya, odwala omwe ali ndi vuto la mtima. Kuphatikiza apo, mankhwala sayenera kugwiritsidwa ntchito mwa odwala omwe ali ndi mavuto amadzimadzi.

Pomaliza

Mwachidule, ziyenera kunenedwa kuti mankhwalawa ndi mankhwala othandiza odwala matenda ashuga kwambiri. Kugwiritsa ntchito moyenera, kutsatira malingaliro a dokotala, poganizira zomwe muli ndi thupi, mankhwalawo ndiotetezeka kwathunthu kwa anthu.

Chifukwa cha izo, kayendedwe ka glucose ndi okosijeni pazinthu zama cellular zimathandizira. Chifukwa chake, gawo lililonse la thupi limadya kwathunthu zomwe limafunikira.

Malinga ndi zotsatira za kafukufuku wa zamankhwala, zotsatira zoyambirira za mankhwalawa zimatha kubwera sabata yachiwiri yogwiritsira ntchito mankhwalawa.

Mphamvu ya Actovegin pothandizira matenda a shuga. Katundu ndi mawonekedwe a mankhwalawa

Ngati mumagwiritsa ntchito Actovegin chifukwa cha matenda ashuga, mutha kufulumizitsa kagayidwe kazinthu zonse, komwe ndikofunikira pakuthandizira matenda. Kuchokera munkhaniyi muphunzira zomwe mankhwalawa ali, momwe odwala matenda ashuga amathandizira thupi komanso momwe angagwiritsire ntchito moyenera.

Kukonzekera kumakhazikitsidwa ndi kufalikira kwa magazi kwa ana ang'onoang'ono, komwe kumatsukidwa kwathunthu ndi zinthu zosafunikira zama protein.

Kuphatikiza apo, Actovegin mumakhala zinthu zotsatsa ndi amino acid, chakudya ndi lipids, ma nucleosides.

Makina ochitapo kanthu amatengera njira yogawa mankhwalawa, chifukwa mphamvu zambiri zimatulutsidwa m'maselo a odwala matenda ashuga. Izi ndizowona makamaka kwa matenda ashuga a 2.

Komanso pokonzekera ndimaphatikizidwe wa sodium, calcium, magnesium ndi phosphorous, chifukwa chomwe magwiridwe antchito a mtima ndi kayendedwe kazinthu, mphamvu ya ubongo imakonzedwa.

Mukamamwa mankhwalawa mthupi lonse, magazi amayenda mofulumira, amakhutitsa maselo ndi minofu ndi michere, mpweya. Izi zimatsogolera ku mfundo yoti magwiridwe antchito obwezeretsanso pama cellular, mabala amachira mofulumira.

Ndizofunikanso kudziwa kuti mankhwalawa amapereka mphamvu kwa minofu ndi minyewa, komwe kumawonjezera kugwira ntchito kwa thupi ndikufotokozera momwe odwala matenda ashuga amakhalira.

Actovegin amapangidwa m'njira zosiyanasiyana:

• Piritsi imagwiritsidwa ntchito pakamwa (mkati),
• madzi njira yothetsera kukapanda kuleka
• jekeseni wamkati
• zonona, mafuta ndi mawonekedwe a gel - zimagwiritsidwa ntchito kunja.

Zizindikiro zambiri pakugwiritsa ntchito Actovegin

Zizindikiro zazikulu za kumwa mankhwalawa:

• magazi osokoneza bongo kupita ku ubongo,
• magazi kulephera mthupi,
• kuvulala kwamtundu wamatumbo
• mamvekedwe osavomerezeka a mtima,
• mawonetseredwe azilonda amitundu yonse,
• mawonekedwe osokoneza khungu,
• mkhalidwe wovuta wa wodwala pambuyo pakupweteka,
• zilonda, mabala ndi necrosis amalo a khungu,
• matenda amisala mu cornea ya maso.

Actovegin zotsatira mu shuga

Pafupifupi nthawi zonse, Actovegin amaphatikizidwa ndi zovuta kuchiza matenda a shuga, chifukwa zimakhudza thupi la odwala matenda ashuga motere:

• mitsempha yomwe imayendera limodzi ndi matendawa imachepetsedwa,
• thupi limayamba kuyankha mwachizolowezi pakubwera kwa glucose,
• kupweteka kumalekezero sikutenga mbali, kotero zolimbitsa thupi sizimamveka kwambiri (zowonjezereka za kupweteka kwa mwendo mu shuga - werengani apa),
• kutsekeka kwa minofu kumachotsedwa,
• minofu yowonongeka, maselo ndi ma khungu zimapangidwanso,
• metabolism imathandizira (metabolism),
• thupi lipatsidwa mphamvu zokwanira, chifukwa chomwe kutopa, kugona ndi kutopa kumatha.
• kuphatikizika kwa magazi kumakhala bwino, komwe ndikofunikira kwambiri kwa odwala matenda ashuga,
• chifukwa cha kuthamanga kwa kayendedwe ka magazi, kusintha kwa atherosulinosis, thrombosis, stroke, kugunda kwa mtima ndi matenda ena amtima wamitsempha.

Ngati tirikunena za momwe mankhwala amodzi angakhalire ndi kuchuluka kwa mankhwala, ndiye kuti tifunika kunena kuti imagwiranso ntchito chifukwa cha insulin. Chowonadi ndi chakuti Actovegin muli ma oligosaccharides, omwe amabwezeretsa magwiridwe antchito a ziwalo zomwe zimayendetsa shuga.

Ndikofunikira kulabadira kuti mankhwalawa amathandizira kuthamanga kwa mamolekyulu a shuga ndi machulukitsidwe amaselo okhala ndi mpweya.

Ichi ndichifukwa chake mankhwalawa ali ndi phindu pa ziwalo zonse, makamaka ubongo.

Ngati mulibe glucose wokwanira mthupi, machitidwe a Actovegin amalimbikitsidwa kukhalabe ndi thanzi la odwala matenda ashuga, koma ngati pali shuga wambiri, limaponderezedwa.

Mankhwala monga mapiritsi amalembedwera maphunziro a miyezi 1 mpaka 1.5. Tsiku lililonse muyenera kumwa mapiritsi 1 kapena 2 katatu patsiku, musanadye, ndi madzi. Machitidwe a yogwira zinthu akuyamba theka la ora itatha, mphamvu yake imadziwika pambuyo pa maola atatu.

Njira yothandizira jekeseni

Njira iyi imatha kuperekedwa ndi makolo, kutanthauza, m'mitsempha, m'mitsempha ndi m'misempha. Migwirizano:

• Pa magawo oyambirira a mankhwalawa, 10 mpaka 20 ml amathandizidwa pa nthawi, ndiye kuti mlingo umachepetsedwa mpaka 5 ml,
• ngati wodwala yemwe ali ndi zilonda zam'mimba komanso zilonda zosachiritsa, yankho limayendetsedwa mu 5 kapena 10 ml tsiku lililonse,
• ndi polyneuropathies motsutsana ndi matenda osokoneza bongo a shuga patsiku, 50 ml ya yankho ndi mankhwala,
• jekeseni wamitsempha imachitika pang'onopang'ono,
• Kutalika kwa maphunzirowa kumatsimikiziridwa ndi adokotala okha.

Drop solution (kulowetsedwa)

Njira yothetsera kukapanda kuleka imapezeka m'magawo osiyanasiyana: 10 ndi 20% ya zomwe zili zofunikira. Amayikidwa makamaka ndi shuga. Migwirizano:

• poyamba 10% yothetsera imaperekedwa mu 250 ml / tsiku, nthawi zina mlingo umachulukitsidwa kawiri,
• kuchuluka kwa jakisoni sikuyenera kuchepera 2 ml pa mphindi,
• Ngati mankhwalawa amaperekedwa kwa nthawi yayitali, ndikofunikira kuwongolera madzi ndi electrolyte bwino mu plasma ya magazi,
• nthawi ya maphunzirayi imatsimikiziridwa ndi dokotala, koma kuchuluka kochepa kwa infusions ndi nthawi 18-20.

Njira zakugwiritsira ntchito kunja

• kwa matenda ashuga, mafuta amatsimikiziridwa kuti amangoyikidwa kokha mu wosanjikiza, makamaka ngati pali zotupa zam'mimba, nthawi zina, mafuta amawayika ngati wosanjikiza.
• mukatha kugwiritsa ntchito, onetsetsani kuti mwaphimba bala ndi kuvala kotayirira ndi kukonza,
• muyenera kusintha bandeji tsiku ndi tsiku,
• kutalika kwa maphunzirawa kumatengera kuchuluka kwa zowonongeka, koma nthawi yochepa ndi mwezi.

• Gel-ngati mafuta imagwiritsidwa ntchito mpaka 6 pa tsiku,
• wosanjikiza ayenera kukhala woonda
• Mtsitsi umapakidwa pakhungu mpaka kulowa bwino,
• itha kugwiritsidwa ntchito ngati pulogalamu,
• Kutalika kwa maphunzirowa ndi masiku 60-60.

Ngati wodwala matenda ashuga amakhudza ziwalo zooneka bwino, madzi am'maso ofunikira amaso ndi ofunikira. Amagwiritsidwa ntchito katatu patsiku 2 akutsikira kwambiri.

• kirimu amapaka katatu patsiku,
• pamaso pa kuwonongeka kwakhungu khungu, wosanjikiza ayenera kukhala wakuda, kenako woonda;
• kirimu wogwiritsidwa ntchitoyo umakhuthulidwa pachilonda,
• ngati kuli kotheka, mutha kuphimba ndi wosanjikiza umodzi wa bandeji.

Contraindication, zotheka zovuta

Ngati mumagwiritsa ntchito Actovegin molingana ndi chiwembu chomwe dokotala wakupatsani, zimachitikira sizimachitika. Kupanda kutero, pakhoza kuwonetsedwa izi:

• kutupa
• redness khungu ndi kuyabwa,
• malungo ndi malungo,
• kuthamanga kwa magazi
• palpitations (tachycardia),
• kupweteka mumtima,
• chizungulire
• kupweteka m'mutu,
• kusanza, kusanza,
• kulephera kudziwa.

• ana osakwana zaka 3,
• mimba ndi mkaka wa m`mawere
• ziwengo kwa mankhwala.

Ndiosafunika kugwiritsa ntchito Actovegin chifukwa cha kulephera kwa mtima, mavuto omwe amapezeka ndi kupuma kwamkodzo.

Mankhwala ofanana ndi Actovegin:

• "Solcoseryl" sapezeka m'mapiritsi okha, ndi analogue yeniyeni,
• "Curantil" imakhazikitsidwa ndi dipyridamole, koma imakhudza kwambiri njira yoyendayenda, ndichifukwa chake imatengedwa ngati analogue ya Actovegin, imapezeka mu mapiritsi ndi zothetsera, koma mtengo wake ndi wokwera kwambiri,
• "Cerebrolysin" amapangidwa pokhapokha povulaza jakisoni, amadziwika kuti ndi nootropic,
• Vero-Trimetazidine ndi waubongo,
• Cortexin imathandizira kagayidwe kachakudya, imakhudza ubongo,
• "Nootropil" imakhazikika piracetam, imakhudza dongosolo lamanjenje ndi ubongo, m'njira zambiri mankhwalawa ndi ofanana ndi Actovegin, ali ndi mtengo wotsika.

Actovegin ndi mankhwala othandiza kwambiri omwe amagwiritsidwa ntchito ndi anthu odwala matenda ashuga. Mankhwalawa alibe maulalo apamwamba kwambiri, chifukwa amagwira thupi kwambiri mokwanira. Ngati mumagwiritsa ntchito mogwirizana ndi cholinga, mudzatha kubwezeretsa ntchito m'makina ambiri amkati.

Actovegin kapena Mexicoidol (jakisoni: ndibwino ndi kusiyana kwanji (kusiyana pamaapangidwe, malingaliro a madokotala)

Jekeseni Actovegin ndi Mexicoidol amathandizira zochizira matenda osiyanasiyana amanjenje ndi mtima, kusokonezeka kwa kagayidwe kachakudya ndi kagayidwe kachakudya ka thupi, kuti apititse patsogolo njira zochizira ubongo. Ngakhale mphamvu ya mankhwalawa ikufuna kuthana ndi matenda omwewo, makina a ntchito zawo ndiosiyana. Zinthu zoterezi zimakupatsani mwayi wopeza zotsatira zabwino zamankhwala.

Makhalidwe Actovegin

Chofunikira chachikulu pa jekeseni ndi gawo lachilengedwe la protein. Chotsitsa chotsikirachi chimasefedwa bwino, kuchotsa zinthu zambiri zosafunikira zomwe zingayambitse zoyipa.

Jekeseni Actovegin ndi Mexicoidol amathandizira zochizira matenda osiyanasiyana amanjenje ndi mtima.

Mu 1 ml ya Actovegin yankho, 40 mg youma yazinthu zomwe zimagwira ntchito zimaphatikizidwa, komanso zowonjezera zina:

Mankhwala amamasulidwa mu galasi ampoules ya 2, 5 ndi 10 ml (pali mitundu yotulutsidwa monga mapiritsi, dragees, mafuta odzola). Poyamba, malonda adapangidwira monga othandizira kusinthika kwa minofu, chifukwa amathandizira kuchiritsa kwamatenda a pakhungu. Koma lero mtundu wa kugwiritsa ntchito kwake wakula. Jakisoni adalowetsedwa kuti abwezeretse thupi ndi zovuta zamtundu wosiyanasiyana:

• sitiroko
• Zotsatira zakuvulala kwam'mutu,
• kukumbukira kusokonezeka, nzeru,
• kusokonekera kwa magazi komwe kumachitika chifukwa chopendekera mitsempha yamagazi (makamaka m'miyendo),
• matenda ashuga polyneuropathy,
• kuwonongeka kwamkati, pakhungu ndi mucous nembanemba.

Zoyipa:

• kukanika kwa impso
• matenda a mtima
• pulmonary edema,
• mavuto ndi kutuluka kwamadzi,
• Hypersensitivity pazigawo,
• zaka mpaka 18 (chifukwa chosadziwa zambiri zokhudza momwe mwanayo alili).

Chikhalidwe cha Mexicoidol

Ubwino wowonjezera wa jakisoni umaperekedwa ndi njira yayikulu yogwira - ethyl methyl hydroxypyridineced (succinic acid mchere). Thupi limakhala ndi antioxidant komanso antihypoxic kwenikweni, likuletsa kuwoneka ngati ma radicals omasuka (zinthu za poizoni zomwe zimakhudza ma cell aubongo).

50 mg yogwira mankhwala ndi zina zowonjezera zimaphatikizidwa 1 ml yankho:

• sodium metabisulfite
• madzi oyeretsedwa.

Ampoules okhala ndi mawonekedwe a parenteral ndi 2 ndi 5 ml (mankhwalawa amapangidwa mwanjira ya mapiritsi). Zifukwa zosankhidwa ndi izi:

• sitiroko
• kuvulala kumutu
• ischemia
• arrhasmia,
• glaucoma
• zotupa zotupa za puritoneum,
• kupsinjika kumatsika
• michere-misempha dystonia,
• encephalopathy
• njira zamantha
• asthenia
• mavuto
• Kuchepetsa kukumbukira ndi kulingalira ntchito,
• vuto la mowa
• kapamba
• zotsatira za kuchuluka thupi.

• matenda a chiwindi
• kulephera kwa aimpso
• Mimba ndi kuyamwa
• Hypersensitivity pazigawo,
• wazaka 18.

Kuyerekeza jakisoni Actovegin ndi Mexicoidol

Zingathe kuchitika:

• kudzera m'mitsempha
• kudzera m'mitsempha
• kudzera mu mtsempha wa magazi.

Zingwe nthawi zambiri zimaperekedwa pamodzi (mu ma syringe osiyanasiyana), chifukwa zimakhala ndi zofananira pakugwiritsa ntchito ndipo zimagwirizana.Ndipo kusiyana m'malingaliro amachitidwe kumangowonjezera mphamvu zawo zochizira.

Jekeseni angathe kuchitidwa intramuscularly.

Mankhwala onse awiriwa amalekerera komanso samayambitsa mavuto, komanso:

• Sinthani kuchuluka kwa mpweya wama cell,
• bwezeretsani magazi m'matumba ang'onoang'ono,
• sinthani magazi kulowa mu ubongo,
• kuteteza neurons
• limbitsa makhoma amitsempha yamagazi
• amathandizira kuyeretsa thupi pakuledzera (kuphatikizapo mowa),
• gawani magawidwe amaselo
• khalani ndi zotsimikizika pamayendedwe a metabolic,
• khazikitsani mapangidwe amitsempha yatsopano m'magazi ofunikira (kuphatikizapo placenta).

Kuphatikiza uku ndikothandiza kwa:

• diabetesic encephalopathy (matenda osokoneza bongo omwe amawonongeka munthawi yomweyo ku GM),
• polyneuropathy (kuwonongeka kwa mitsempha yotumphukira),
• VVD, yowonetsedwa ndi mantha,
• kuphatikiza kwa mtima ischemia ndikuchepetsa magazi kupita ku GM.

Ndizololedwa kumwa mankhwala nthawi imodzi ndi njira zambiri:

• ma pinkiller
• zoziziritsa kukhosi
• antimicrobial
• anticonvulsants.

Actovegin, yokonzedwa ndi magazi a ng'ombe, imakhala ndi zinthu zolimbitsa thupi, zomwe mu Mlingo wina mumapezeka munthu aliyense.

Kodi pali kusiyana kotani?

Kusiyana kwakukulu kumagwera mu kachitidwe kachitidwe. Actovegin, yokonzedwa kuchokera ku magazi a ng'ombe, imakhala ndi zolimbitsa thupi zomwe zimapezeka mu Mlingo wina mwa munthu aliyense. Mavuto owonjezereka omwe amalowa m'matumbo a chofooka:

• yambitsa kagayidwe kazinthu,
• kuchuluka kwa mpweya ndi shuga,
• onjezerani kukhudzika kwa chidwi chawo.

Actovegin, kulowa mthupi, kumalimbikitsa ntchito za omwe amayendetsa glucose, ma glutamines Glut 1 ndi Glut 4, omwe amatsogolera pakupitilira kwa glucose mayendedwe onse amisempha, kuphatikiza kudutsa mu zotchinga zamagazi mu ubongo.

Kuchita bwino kwa njirayi kunatsimikiziridwa mwa kuyeserera mu 2009 popereka mankhwala kwa odwala omwe ali ndi polyneuropathy motsutsana ndi mtundu II shuga mellitus (atatha jekeseni, kuchepa kwa hemoglobin HbA1C kunadziwika).

Zochita za Mexicoidol zimakhazikitsidwa ndi zoletsa zomwe zimapangitsa kuti ma free radicals ndi lipid peroxidation. Njira izi ndi:

• yambitsani antioxidant enzyme superoxide dismutase,
• phatikizani ndi zida zopanga ma mitochondria,
• sinthani mphamvu yama cellular,
• zimakhudza mphamvu yamankhwala am'mimba a nembanemba,
• onjezani zomwe zidutswa za polar lipid (phosphotidylserine ndi phosphotidylinositol) mu nembanemba,
• kuchepetsa kuchuluka kwa cholesterol kukhala phospholipids, kuchepetsa mamasukidwe akayendedwe a lipid ndikuwonjezera kuthamanga kwa membrane.

Zochita za Mexicoidol zimakhazikitsidwa ndi zoletsa zomwe zimapangitsa kuti ma free radicals ndi lipid peroxidation.

Ntchito yachilengedwe ya nembanemba yomwe imachitika chifukwa cha ethyl methyl hydroxypyridine exrate imakhudza ntchito ya michere yomwe imathandizira kugwira ntchito kwa ma neurotransmitters. Maloidol amatsitsa cholesterol ndikuwonjezera kuchuluka kwa lipoproteins yapamwamba.

Mphamvu za antioxidant yankho zimatheka chifukwa chokhoza kusanthula ntchito ya ma receptors ndi ma ion ma phokoso, kukonza ma signaptito a synaptic pakati pa kapangidwe ka ubongo. Chifukwa cha izi, Mexicoidol imakhudza maulalo ofunikira mu pathogenesis yamatenda ambiri, imagwira mawonekedwe osiyanasiyana ochitika ndi zovuta zazing'ono komanso kawopsedwe ochepa.

Contraindication kutenga Mexicoidol ndi mimba ndi mkaka wa m`mawere. Actovegin akuwonetsedwa pa gestation pachiwopsezo cha hypoxia. Koma mankhwalawa, chifukwa cha mawonekedwe a mapuloteni omwe amagwira ntchito, nthawi zambiri amakhumudwitsa ziwengo, zomwe zimayambitsa edema ya Quincke.

Wopanga Mexicoidol - kampani yakunyumba PC Pharmasoft. Actovegin imaperekedwa ku msika wogulitsa mankhwala ndi onse Russia (Sotex) ndi Austria (Takeda Austria GmbH).

Zomwe zimakhala zotsika mtengo

Mitengo 4% ya Actovegin mu ampoules:

• 2 ml No. 10 - 560 rub.,
• 5 ml No. 5 - 620 rub.,
• 10 ml No. 5 - 1020 rubles.

Mitengo ya 5% r. Mexicoidol:

• 2 ml No. 10 - 439 rub.,
• 5 ml No. 5 - 437 rub.,
• 5 ml No. 20 - 1654 rub.

Zomwe zili bwino kuposa jakisoni Actovegin kapena Mexicoidol

Mukamasankha mankhwala, dokotala aliyense amatengera matenda, matendawa ndi kulolerana kwake. Kutengera ndi magwiritsidwe a ntchito ya chinthu, Actovegin ndi yoyenera kwa ma pathologies a zotumphukira ziwiya. Gawo lalikulu la Mexicoidol limathandizira kutaya magazi m'magazi, kuchititsa mankhwala pang'onopang'ono, koma modalirika.

Actovegin ndi othandiza kwambiri kwa:

• kusokonekera kwamphamvu kwazidziwitso,
• dementia
• Matenda a Parkinson
• matenda ashuga polyneuropathy.

Mexidol iyenera kulembedwa ngati:

• mtima ischemia
• kusokonekera kwa dongosolo la ziwonetsero zamagetsi,
• vuto la mowa
• nkhawa zochulukirapo.

Pankhani yamavuto am'msana, Actovegin amalembedwa kuti asayankhe zovuta zamitsempha zomwe zimayambitsidwa ndi kupindika kwa mitsempha yotupa ndi ma intervertebral discs kapena zida zoyandikana.

Yogwira ntchito pophatikizira imadyetsa mizu ya mitsempha, imagwira ntchito pazitsulo zamtunduwu zomwe zimayambitsa magazi kupita kumusana.

Mexicoidol sachita pa zotumphukira zamanjenje, koma chapakati.

Irina, wazaka 41, Nizhnevartovsk

Ndimagwiritsa ntchito mankhwalawa pobwezeretsa zovuta zamagazi ndikulimbitsa mitsempha yamagazi. Ndidachita kutero. Ndimayenera kupita kuchipatala m'mawa kwambiri. Ndidafunsa adotolo kuti andithandizire kuyendetsa matenda a mu mnofu, chifukwa ndimatha kutero kunyumba. Zololedwa. Koma mapangidwe ake amkati anali ocheperako, ma ampoules asanu okha, ndipo intramuscularly amafikira jakisoni 10.

Olga, wazaka 57, mzinda wa Tambov

Dokotala wamitsempha anapangira mayendedwe ophatikizana a mwamunayo kwa mtima wake wam'mimba. Dokotalayo adanena kuti Mexicoidol imathandiza aliyense kawiri pachaka kwa jakisoni 10, makamaka munthawi yopuma, thupi likafooka.

Kira, wazaka 60, Chekhov

Odwala VVD. Kamodzi pachaka ndimakumba mapangidwe awa, kuphatikizapo mavitamini. Maloidol amalekeredwa bwino, koma zotsatira zake zimachedwa. Actovegin imagwira mwachangu, koma mtengo wokwera komanso mawonekedwe owoneka osiyanasiyana.

Cholepheretsa kutenga Mexicoidol ndi mimba. Actovegin akuwonetsedwa pa gestation pachiwopsezo cha hypoxia.

Ndemanga za madotolo zokhudza jakisoni Actovegin ndi Mexicoidol

V.V. Purysheva, othandizira, Perm

Ndimapereka jakisoni 2 pachaka kwa masiku 10, nthawi zina ndimachulukitsa mpaka mwezi, koma kale ndimankhwala olimba. Ndimawonjezera mavitamini ku chiwembu (mwachitsanzo, Milgamm). Koma kusankhidwa kulikonse kuyenera kuchitika pokhapokha malinga ndi dokotala.

T.S. Degtyar, wamisala, Moscow

Ndimawonjezera Mildronate kuphatikiza ndikupanga ischemia, pambuyo pa stroko, kuvulala pamutu, ndi matenda ena oopsa. Mu mtundu wa matope, mankhwalawa amamwa bwino, ndipo mpumulo umabwera mwachangu. Mildronate imapangidwanso bwino kudzera m'mitseko. Koma pakakhala kukonzekera kwamankhwala ambiri mu chiwembu, ndikofunikira kuti mupewe mlingo.

M.I. Kruglov, osteopath, Kursk

Kuphatikizika uku kukuwonetsedwa chifukwa cha zovuta za osteochondrosis, ndikuwonjezera Milgamm, yomwe imasintha bwino njira zochizira. Yambani ndi jakisoni 10. Zonsezi ndi zina zimatha kudindidwa mu / mu kapena / (Milgammu mu / m).

Pambuyo jakisoni, amasinthana ndi mapiritsi ndikuwamwa kwa miyezi itatu. Kugwirizana kumeneku ndi kowopsa chifukwa cha ziwopsezo, popeza mapuloteni a Actovegin, komanso mavitamini B, omwe ali ku Milgamma, amadzetsa mavuto.

Kodi mapiritsi kapena jakisoni actove bwino ndi chiti?

Anthu angapo amadziwa za kuchiritsa kwa Actovegin. Ndemanga zikuwonetsa kuti zimapangitsa kagayidwe kazakudya zam'mimba ndikuthandizira magazi. Komabe, akadali ndi chidwi ndi funso lazomwe zili bwino kuposa mapiritsi kapena jakisoni a Actovegin. Izi ndi zomwe tiyesera kudziwa m'nkhaniyi.

Zizindikiro zogwiritsidwa ntchito

Actovegin amapangidwa pamaziko a kunyongedwa kwa hemoderivative ku magazi a ng'ombe. Monga tawonera kale, zimapangitsa kagayidwe kachakudya pama cellular level, kamene kamatsimikizira kuti mpweya wabwino umapezeka kuzinthu zowoneka bwino komanso kuwonjezera magazi. Patsamba lamayikidwe a mankhwala mumatha kuwona mafuta, mafuta, mapiritsi ndi jakisoni.

Chipangizocho chikuyenera kuperekedwa ndi adokotala okha. Tsitsi ndi mafuta, amathandiza ndi zotupa pakhungu, zilonda zamkati ndi zopsinjika.

Malangizo ogwiritsira ntchito akuwonetsa kuti mapiritsi a Actovegin ndi omwe amaperekedwa chifukwa cha matenda monga:

• sitiroko
• kusokonezeka kwa magazi muubongo,
• TBI,
• dementia
• matenda ashuga polyneuropathy,
• kuvulala kwamitsempha
• ulcerative process of trophic chikhalidwe,
• angiopathy.

Pogwiritsa ntchito jakisoni a Actovegin, zikuwonetsa zomwezo. Kusankhidwa kwa mawonekedwe a kumasulidwa kwa mankhwalawa kudzatengera kuopsa kwa matenda.

Malangizo omwera mankhwalawa

Jakisoni amagwiritsidwa ntchito jakisoni wamkati ndi mu mnofu, amathanso kukhala dontho.

Pa magawo oyamba a mankhwala othandizira, mlingo umakhala wokwera, pakapita nthawi umakhala wocheperako. Pakutha kwa chithandizo, amaloledwa kulowetsa jakisoni wa Actovegin ndi mapiritsi. Mwambiri, nthawi yayitali imakhala masiku 30-45.

Ponena za piritsi la mankhwalawa, ayenera kumwedwa. Nthawi zambiri, madokotala amalimbikitsa kuti odwala awo amwe mapiritsi atatu katatu patsiku. Pambuyo pothandizidwa ndi chithandizo, mlingo wa tsiku ndi tsiku umachepetsedwa.

Muubwana, mankhwalawa amatha kumwa ngati mwana wafika zaka zitatu, mlingo wa tsiku ndi tsiku ndi piritsi limodzi.

Contraindication ndi zoyipa zimachitika

Monga mankhwala aliwonse Actovegin ali ndi ma contraindication angapo, amaphatikiza

• oligouria,
• pulmonary edema,
• Anuria
• kulephera kwa mtima
• tsankho
• mimba mu trimester yoyamba.

Zotsatira zake zoyipa, kugwiritsa ntchito mankhwalawa kungayambitse:

• thupi lawo siligwirizana mu urticaria,
• hyperhidrosis
• kuchuluka kwa kutentha kwa thupi,
• maonekedwe a kuyabwa
• lacure
• Hyperemia wa sclera.

Madontho a shuga

Matenda a shuga ndi endocrine matenda omwe amachititsa kuti thupi lonse lisinthe.

Madontho a matenda ashuga amagwiritsidwa ntchito yonse kukonza thanzi la wodwalayo komanso kupewa zovuta, komanso kumuchotsa pamkhalidwe wowopsa.

Monga lamulo, odwala matenda ashuga amtundu wa 1 amafunikira omwe akutsikira, chifukwa chowonjezera chowopsa cha kuwonongeka kwadzidzidzi ndikukhala bwino.

Komabe, omwe amathira matenda ashuga amtundu 2 nawonso samasiyanitsidwa. Mothandizidwa ndi kulowetsedwa kwa intravenous, ndizotheka kukhazikitsa mkhalidwe waumoyo wa anthu ndikupatuka kwina kwazomwe zikuchitika.

Madontho a thanzi labwino

Kufunika kwa otsika kwa odwala matenda ashuga komanso kapangidwe kawo kumatsimikiziridwa ndi katswiri wozikidwa pa:

• kuchuluka kwa shuga m'thupi,
• kupatuka pachizindikiro cha kuthamanga kwa magazi,
• owonjezera lipid wambiri.

Ndi zizindikiro zabwinobwino za kuthamanga kwa magazi, komanso kuchuluka kwa shuga ndi ma lipids m'thupi, kugwiritsa ntchito ma dontho sikungathandize, koma kungayambitse kuwonetsa kosayenera

Pankhaniyi, simuyenera kudzimvera chisoni ndipo ngati mukumva kuwawa, muyenera kufunsa dokotala yemwe angakuthandizeni kusankha kusankha mankhwala oyenera.

Mankhwalawa amathandizidwa ndi shuga kapena saline ndikuthira m'mitsempha ndi dontho la 250 ml mpaka 500 ml. Njira ya mankhwala pafupifupi njira 20.

"Actovegin" imapezeka mu mawonekedwe a mapiritsi, gel, mafuta, zonona, njira zothetsera jakisoni ndi kulowetsedwa. Ndi kulowetsedwa kwa mankhwalawa komwe kumakupatsani mwayi wopeza zotsatira zabwino

Actovegin ali ndi zotsatirazi m'thupi la odwala matenda ashuga:

Timalimbikitsanso kuwerengera: Mpumulo yodzidzimutsa yothandizira odwala matenda ashuga

zimathandizira kusintha kulolera kwa glucose chifukwa cha insulin-like, i.e.

ali ndi vuto la antiidiabetes, kafukufuku adazindikira kuti mankhwalawa amachotsa kapena kuchepetsa mawonekedwe a matenda a shuga: kuchepetsa ululu ndi dzanzi la madera omwe akukhudzidwawo, kusintha kukhudzika kwawo.

Izi sikuti zimangowongolera mkhalidwe wamaganizidwe a odwala, komanso zimakupatsani mwayi wolimbitsa thupi,

Pambuyo kulowetsedwa mankhwala ndi mankhwala, m`kamwa makonzedwe n`zotheka.

Nthawi zina, kugwiritsa ntchito mankhwalawa kumabweretsa: kufooka, thupi lanu siligwirizana komanso kuwonjezeka kwa kutentha kwa thupi.

Komanso Actovegin ndi yosavomerezeka kuti igwiritsidwe ntchito:

• musanafike zaka zitatu,
• ndimomwe thupi limagwirira ntchito pazigawo za mankhwala,
• ndi kuphwanya ntchito ya mtima ndi mapapu,
• pa mimba ndi kuchitapo.

Monga lamulo, mankhwalawa amavomerezedwa bwino ndi odwala, mavuto omwe samachitika kawirikawiri.

Mankhwala amathandizira:

• Kuthanso kwamitsempha yamagazi, kukonza ma cellcirculation, omwe amachepetsa chiopsezo cha thrombosis,
• kuchuluka kwawonekera m'zotengera chifukwa cha kuchuluka kwa adenic acid pamakoma awo,
• kuchuluka kwamankhwala olimbitsa mtima chifukwa choletsa ntchito ya enzyme phosphodiesterase,
• kumasuka kwa minofu yosalala yamitsempha yamagazi, kukulitsa pang'ono makoma awo, pomwe kwenikweni sikusintha kugunda kwa mtima,
• matenda a kupuma kwam'manja mu zimakhala zamkati zamanjenje, impso, mikono ndi miyendo,
• Sinthani kagayidwe kachakudya mu chapakati mantha dongosolo ndi magetsi magwiridwe ake,
• kuthamanga kwa magazi kumadera otumphukira miyendo.

Yogwira ntchito ya Trental ndi pentoxifylline, yomwe imapatsa mankhwalawa vasodilating

Kwa odwala matenda ashuga, mankhwalawa amalembera zotumphukira zamagazi zomwe zimayambitsa ma atherosulinotic pathologies (diabetesic angiopathy), trophic zilonda zam'mimba, ischemic mamiriro, kusokonezeka kwa magazi m'maso, ndi zina zambiri.

Katswiriyo amawona kuchuluka kwa mankhwalawa omwe amayenera kugwiritsidwa ntchito kwa wodwala, kutengera thanzi la wodwalayo komanso momwe akufunira.

Trental imakhala ndi zoyipa zambiri komanso zotsutsana, zomwe zimapangitsa kugwiritsidwa ntchito kwake kukhala kosatheka popanda mankhwala a dokotala.

Mankhwala a shuga samangoteteza nembelera komanso kumenya zopitilira muyeso, komanso amatsogolera ku:

• kuchuluka kwa okosijeni wamagazi,
• kusintha kayendedwe ka magazi, komanso mphamvu zake za rheological (mamasukidwe akayendedwe ndi madzi),
• kuchepetsa cholesterol mthupi,
• kutsegula kwa mphamvu ya maselo,
• kupewa kusintha kwa pathological ndi kukonzanso kwa kusintha kwa atherosulinotic m'makoma amitsempha yamagazi.

Chofunikira chachikulu cha Mexicoidol ndi ethyl methylhydroxypyridine desine, yomwe imatsimikiza mawonekedwe ake a antihypoxic ndi antioxidant

Mexicoidol ndiyofunika makamaka mu matenda am'mimba a m'mimba, chifukwa chakutha kuthetsa kusokonekera kwa metabolic ndi mtima muubongo, komanso kubwezeretsa kuyankhula, kukumbukira, chidwi, luntha ndi mawonekedwe ena a matendawa.

Mankhwalawa sagwiritsidwa ntchito kwa hypersensitivity ku zigawo zake, komanso kusintha kwamatenda a chiwindi ndi impso, ndi zina zambiri.

Monga lamulo, otsikira ndi Mexicoidol amapatsidwa tsiku lililonse kuyambira 2 mpaka 4 pa mlingo wa 200-500 mg kwa masiku 10-14 ndi kuchepa kwinanso.

Reopoliglyukin

Mu shuga, mankhwalawa amagwiritsidwa ntchito:

• Pewani magazi
• sinthani magazi osasinthika amitsempha,
• sinthani zinthu zapoizoni m'thupi,
• pewani kuphatikiza kwa magazi.

"Reopoliglyukin" limasinthasintha mamasukidwe amwazi ndi kuthamanga kwa magazi mthupi

Reopoliglyukin ali ndi zotsutsana ndi zoyipa, kuphatikiza: kudumpha mu kuthamanga kwa magazi, chizungulire, kutentha thupi ndi mawonekedwe ena olakwika mpaka anaphylactic.

Komanso, omwe amathira shuga "Reopoliglukina" sagwiritsidwa ntchito pamodzi ndi yankho la shuga (5%).

Kugwiritsa ntchito mankhwalawa mwa kulowetsedwa kuyenera kuchitika moyang'aniridwa ndi dokotala mpaka katatu m'masiku 7, muyeso wa 400 ml. Njira ya mankhwalawa imayambira 6 mpaka 8.

Zowoneka za dropers zimawonetsedwa mu chikomokere, kupezeka kwake komwe kumatheka ndi matenda a shuga ndipo wodwala amafunikira chithandizo chamankhwala mwachangu. Tiyenera kudziwa kuti mankhwalawa amathandizika malinga ndi momwe wodwalayo alili komanso mawonekedwe a matendawa.

Ketoacidotic chikomokere

Kuti muchotse wodwalayo chikomokere ndi chithandizo chotsatira, akatswiri mu zovuta zomwe amagwiritsa ntchito:

• kulowetsa insulin m'mitsempha kapena intramuscularly kuchokera ku 10 mpaka 20 mayunitsi. Kenako, dontho lokhala ndi insulin limagwiritsidwa ntchito (mayunitsi 0,1 pa kilogalamu imodzi ya kulemera kwa wodwalayo kapena kuchokera ku magawo 5 mpaka 10 pamphindi 60),
• Dzazani thupi ndi madzi pogwiritsa ntchito saline ya thupi kuchokera pa 5 mpaka 10 ml pa 1 makilogalamu amalemu 1 mpaka 3 maola,
• ikani dontho ndi glucose (5%) ndi sodium chloride (0,45% yankho) pomwe kuchuluka kwa shuga mthupi kumatsikira mpaka 16 mmol / l.

Hyperosmolar chikomokere

Njira zoyambirira zochotsera wodwalayo kukomoka zimatsatiridwa ndi kulowetsedwa kwa mankhwala otsatirawa:

• Mukamachepetsa kuthamanga kwa magazi: sodium chloride (0.9% yankho) ndi shuga (5% yankho) pamlingo kuchokera 100 mpaka 2000 ml,
• ndi ochepa matenda oopsa, iwo amagwiritsa ntchito dontho lokhala ndi magnesium sulfate kapena kapena ku intravenous management,
• kusowa kwamadzi kumatha ndi kukhuthala kwa 0,9% sodium chloride mu voliyumu kuchokera ku 1000 mpaka 1500 ml ola loyamba. Maola awiri otsatira, kuchuluka kwa mankhwalawa kumachepa ndikuchokera ku 500 mpaka 1000 ml, mtsogolo - kuchokera 300 mpaka 500 ml,
• pa mphindi 60 zoyambirira 5% yankho la glucose imayambitsidwa motsika kuchokera ku 1000 mpaka 1500 ml, kenako kutsika kwa maola awiri kuchokera 500 mpaka 1000 ml, ndiye kuchokera 300 mpaka 500 ml.

Cholinga chachikulu cha njira zochizira, pomwe wodwala amachotsedwa pa hyperosmolar coma, ndikuti: kubwezeretsa magazi pH, kuchotsa kutulutsa madzi m'thupi ndi kuphatikizira kuchuluka kwa shuga m'thupi

Mofananamo, mankhwala a insulin omwe ali ndi ma dontho amachitika.

Wodwalayo amayesedwa pafupipafupi, kutengera zotsatira zake, Mlingo wa mankhwala omwe amagwiritsidwa ntchito umasiyana.

Momwe mungachepetse msanga magazi kwa odwala matenda ashuga?

Ziwerengero za anthu odwala matenda ashuga zikuwonjezeka chaka chilichonse! Russian Diabetes Association imati munthu m'modzi mwa anthu 10 m'dziko lathu ali ndi matenda a shuga. Koma chowonadi ndichakuti si matenda omwewo omwe amawopsa, koma zovuta zake ndi moyo womwe umawatsogolera.

Actovegin a 2 shuga

Zaka makumi angapo zapitazi, kuchuluka kwa anthu odwala matenda ashuga kwachuluka, makamaka chifukwa cha matenda a mtundu 2. Izi nthawi zambiri zimakhudzana ndi kuwonjezeka kwachuma padziko lonse lapansi, kuphwanya kwamakhalidwe a anthu ndi zakudya, komanso kupsinjika kwakanthawi. Popeza ziwiya za thupi lonse zimavutika ndi matendawa, chiopsezo chokhala ndi zotumphukira za mtima zimayamba. Matenda akuluakulu kwambiri a etiology iyi ndi kugunda kwamtima ndi stroko. Pankhaniyi, pakufunika kuwongolera kwathunthu kwa thupi ndi chitukuko cha chithandizo, poganizira mawonekedwe a matendawa.

Limagwirira mankhwala

Actovegin imayambitsa kusintha kwa mphamvu zama metabolism mu zimakhala, zomwe zimatheka pogwiritsa ntchito njira zingapo:

• Chifukwa cha kuchuluka kwa ma phosphates okhala ndi mphamvu zambiri.
• Mwa activating michere nawo oxidative phosphorylation.
• Powonjezera zochita za maselo.
• Chifukwa chowonjezeka chomanga thupi ndi mapuloteni m'thupi.
• Kuwonjezeka kwa chiwopsezo cha glucose m'thupi.
• Kuyambitsa magwiridwe antchito a ma enzyme omwe amawononga shuga, sucrose.

Zochita za Actovegin za anthu osafuna shuga omwe amadalira insulin

Pazakuyesa zamankhwala, mankhwala ake a insulin anawululidwa. Mukuwerenga izi, zidawululidwa kuti oligosaccharides ndi gawo limodzi la hemodialysis. Popeza zikuwululidwa kuti choyambitsa matenda a shuga a 2 ndikukula kwa insulin, kukhazikitsidwa kwa zinthu monga insulin mthupi kumatha kuchepetsa milingo ya shuga:

• Ma oligosaccharides omwe ali mu kukonzekera kwa Actovegin kwa matenda amtunduwu amayambitsa zochitika za onyamula shuga, zomwe ndizofunikira kwambiri kuti zitheke. Pali mitundu isanu yaonyamula, iliyonse yomwe imafunikira gawo lake. Nthawi yomweyo, kutsegula kumachitika popanda kugwiritsa ntchito insulin receptors.

Actovegin imachulukitsa mayendedwe a glucose ndi kuchuluka kwa mpweya m'maselo, momwe mtundu wa 2 shuga umatanthawuza kukhazikika kwa misempha ya glucose pamlingo wosalekeza.

Phunziro la insulin-like Actovegin

Maphunziro a mankhwalawa adachitika mu zikhalidwe za khungu ndi nyama. Kuti atsimikizire ntchito yake motsutsana ndi ziwalo za 2 za matenda a shuga, odwala 20 omwe ali ndi matenda am'mimba komanso anthu angapo athanzi adatengedwa. Magulu onsewa adapemphedwa kumwa mankhwalawa mkati mwa masiku 14. Kusintha kwa kulolerana kwa mafuta m'gulu loyambalo kunakhazikitsidwa ndi kuchuluka kwa insulin. Nthawi yomweyo, mankhwalawa analibe mphamvu yathanzi lathanzi.

Pali maphunziro omwe akuwonetsa kuchepa kwa insulin. Chifukwa cha izi, odwala matenda amtundu wa 2, odwala 10 adalandira Actovegin kwa masiku 10. Pambuyo pa mankhwala, kukana kunachepa ndi 85%, zomwe zikuwonetsa kuwonjezeka kwa shuga. Phunziroli limatsimikizira kugwiritsidwa ntchito kwa mankhwalawa, ngakhale ndi njira yochepa yoyendetsera.

Chiyeso chotsatira chinawonetsa mwayi wochepetsera chiopsezo chokhala ndi zovuta za matenda ashuga pamene mankhwala adalowetsedwa. Mwa izi, anthu 70 omwe ali ndi matenda ashuga polyneuropathy adagwiritsidwa ntchito. Njira ya chithandizo inali masabata 24. Kuchepetsa kwa zizindikiro za matendawa kumawonedwa kale pa masabata a 16 atamwa mankhwalawa, zomwe zimaloleza kuchepetsa mlingo womwe waperekedwa.

Zotsatira za Actovegin pa polyneuropathy

Zotsatira za kafukufukuyu, zotsatira zingapo zidadziwika:

• Actovegin imasintha bwino.
• Mankhwala amawonjezera kuthamanga kwa kukhumudwa kwa mitsempha, kutsimikiza mtima kugwiritsa ntchito ma Hardware.
• Imachepetsa kugunda kwamphamvu, kupweteka, chilengedwe.
• Amachepetsa ululu.
• Kuchulukitsa mtunda womwe wodwala amatha kuphimba.

Kuchita mayeso okometsera pakamwa kumatsimikizira kuchepa kwa kuchuluka kwa glucose ndikusintha kwa insulin pambuyo pa actovegin mankhwala okhala ndi katundu wa carbohydrate. Nthawi yomweyo, anthu athanzi adakhalabe osasinthika.

Kugwiritsa ntchito mitundu ya Actovegin a shuga

Kupweteka kwamankhwala kwamankhwala kumadziwika. Katunduyu ndiwofunika kwambiri kwa odwala omwe amakonda kukumana ndi zilonda pakhungu lanu.

Actovegin ali ndi zochitika zotsutsana ndi zotupa zapakhungu zotsatirazi:

• zilonda zam'mimba
• kutentha kwa madigiri 1-2,
• kuwoneka kwa zilonda za kupsinjika,
• kupezeka kwa kuwonongeka kwa ma radiation.

Kulimbana ndi mankhwalawa ndi zovuta

Odwala a 2 odwala matenda a shuga nthawi zambiri amakumana ndi zovuta: phazi la shuga, retinopathy, polyneuropathy, angiopathy:

1. Poyerekeza ndi phazi la odwala matenda ashuga, makonzedwe amkati amathandizira kuchiritsa kwa phazi ndikupangitsanso ntchito yake. Kupititsa patsogolo vutoli, mitundu yamankhwala imagwiritsidwa ntchito - ngale, mafuta. Poyamba, pokhapokha chilonda chitapangidwa, ndikofunikira kupha tizilombo toyambitsa matenda ndikuwabwezeretsanso. Pa gawo la granulation, Actovegin amagwiritsidwa ntchito ngati gel. Pa siteji ya mapangidwe apangidwe, kirimu ndi mafuta angagwiritsidwe ntchito.
2. Zotsatira za polyneuropathy zafotokozedwa pamwambapa.
3. Angiopathies nthawi zambiri amadziwonetsera pofufuza zamkati mwa odwala matenda ashuga. Panthawi ya kulekerera glucose, pali zovuta mu fibrinolysis mu zotupa, kuchuluka mtima kupindika ndi kusokonezeka mgwirizano wa minofu yamtima. Actovegin mukamamwa ndi shuga yemwe samadalira insulini amalola kuchepa kwa njala yam'mimba komanso minyewa yamagazi. Izi zimazindikira malo a vuto la mtima ndipo zimapangitsa kuti ziwonjezeke.
4. Angiopathies a zombo zazing'onoting'ono zimaphatikizapo kuwonongeka kwa retinal chifukwa cha kuperewera kwa matenda a retinal arterioles.

Chifukwa chake, matenda amtundu wa 2 ndi matenda ovuta kwambiri omwe sangathe kuwongolera kuchuluka kwa shuga. Nthawi zambiri imayendera limodzi ndi mawonekedwe a zovuta, zomwe zimafuna njira yolumikizirana yothandizira. Actovegin wagwiritsidwa ntchito kwazaka zoposa 50, komabe, ndi matenda amtunduwu amagwiritsidwa ntchito posachedwapa. Mphamvu za mankhwalawa zimathandizira kuyendetsa shuga m'magazi, kuwonjezera trophism ya maselo ndi zimakhala, kuchiritsa mabala komanso kuchepetsa insulin. Zonsezi zimakuthandizani kuti mukwaniritse kukhululukidwa kwa wodwala yemwe ali ndi matenda a shuga a insulin. Mankhwalawa ndi otetezeka komanso othandiza, angagwiritsidwe ntchito ndi amayi apakati omwe ali ndi zovuta zovuta za matendawa.