Pancreatic enzyme akusowa: Zizindikiro ndi chithandizo
Kuchuluka kwa ziwalo zam'mimba zamagetsi zomwe zimakhala ndi endocrine ntchito secrete pancreatic madzi, omwe amakhala ndi ma enzymes. Zotsatira zazomwe zimayambitsa, enzymatic pancreatic insuffence grow. Kodi ndi ziti zomwe zimapangitsa kuti matenda azitsamba azikhala? Kodi chofunikira ndi chiyani kuti mubwezeretse zachilengedwe?
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Magulu a michere ndi zochita zawo
Chigoba chaching'ono chimapezeka pansipa ndi kumbuyo kwa mimba. Pancreas ili pafupi ndi msana pamlingo winawake - m'chigawo cha chapamwamba cha lumbar vertebrae. Mtundu wake wopingasa umafanana ndi chilembo "S". Itha kupukusa mpaka malita 4 a kapamba wa pancreatic patsiku. Mchitidwewo umayamba munthu akangodya chakudya. Ntchito ya chinsinsi imapitilira kwa maola angapo.
Madzi a pancreatic ndi 98% madzi. Gawo lotsalalo likugwera pa ma enzymes (ma enzymes). Zinthu zachilengedwe izi ndi mapuloteni m'chilengedwe. Amathandizira kusintha kwachilengedwe kwamphamvu mthupi. Zokha siziyenera kuwonongedwa ndikuwonongeka. Koma pali zifukwa zomwe zimayambitsa zotsatirapo - kusowa kwa ma enzymes kapena kusachita. Mwachitsanzo, asayansi azachipatala atsimikizira kuti ma enzyme amagwira ntchito pafupipafupi kwambiri ma hydrogen ion ndi zina mwa zinthu zina.
Imadziwika ndi michere ya ma enzymes ndi kusankha kwawo. Iliyonse ya zida zomwe zimagwira ntchito kwambiri zimangoyang'ana pagulu lazinthu zake:
- lipase limaphwanya mafuta,
- trypsin (chymotrypsin) - mapuloteni,
- amylase - chakudya.
Ma Enzymes amagwira ntchito pamankhwala osokoneza bongo omwe ali ndi kulemera kwakukulu kuti athe kuwapangitsa kupanga magawo osavuta: mapuloteni - amino acid, chakudya - ku monosaccharides.
Zomwe Zimayambitsa ndi Zizindikiro za Kukanika
Madzi a m'mimba amatuluka kudzera mu duodenum kupita m'matumbo. Ndi kuchepa kwa ma pancreatic enzymes, zakudya sizimamwa, khalani osaperewera. Matendawa amatha kubereka, kuchokera kwa makolo kupita kwa ana. Imapezedwa pa moyo, mwa mawonekedwe ake oyamba - chifukwa cha kusintha komwe kumakhudzana ndi chimbudzi (zokhudzana ndi zaka, atrophy, kuwonongeka kwa makina - miyala mu ma pancreatic ducts, zotupa, zipsera).
Matenda a enzymatic amatenga mawonekedwe achiwonetsero osakhudzidwa ndi ziwalo (atherosermosis, matenda a shuga, kunenepa kwambiri, kuperewera kwa zakudya m'thupi). Njira zakuzindikira zimakupatsani mwayi wodziwitsa kapena kuchepa kwathunthu kwa michere mthupi.
Nthawi zambiri, zizindikiro za kuchepa kwa enzymatic zimawonekera ngati zovuta za pachimake komanso chifuwa chachikulu cha kapamba.
Wodwalayo akhazikitsa kuphwanya kwa zamisala molingana ndi zizindikiro zotsatirazi:
- kuchepa thupi pang'onopang'ono
- kutulutsa pafupipafupi,
- vuto
- kutsegula m'mimba.
Dokotala wa gastroenterologist wogwiritsa ntchito njira zasayansi yophunzirira katulutsidwe wakunja wa kapamba (kuyezetsa kafukufuku, mapulogalamu, kudziwa mulingo wa michere), njira zothandizirira (ultrasound, MRI, CT, radiography) imatsimikiza kuchuluka kwa enzymatic pancreatic insuffence.
Osaphulika ma molekyulu opaka mafuta okhala mu manyowa. Anthu oyamba:
- kuchuluka kuchuluka
- osapangidwa, amadzimadzi,
- kukhala ndi fungo la fetid
- imvi chamafuta.
Chithandizo cha Zizindikiro cholinga chake ndikuchotsa mawonetseredwe a enzymatic kusalinganika. Izi zimafuna kuwonjezeka kwa 100% kwamadzi achinsinsi. Akatswiri amati odwala omwe ali ndi matenda a shuga, zotsatira za kuwongolera pamankhwala nthawi zambiri zimakhala zabodza. Kuyesa kwabwino kwa ziwalo zopanda ntchito.
Zoyambitsa ndi Zopezeka Zomwe Zimapangitsa Kuti Muli ndi Enzyme
Matenda omwe kapamba sangathe kutulutsa madzi am'mimba kuchokera masiku oyamba a moyo amatchedwa hypoplasia. Zikuwoneka nthawi yomweyo. Amayamba chifukwa chakukula kwa thupi. Mwanayo akuzunzidwa ndi chizindikiro chachikulu komanso chodziwikiratu - kutsegula m'mimba pafupipafupi. Kutsekula m'mimba kumachitika chifukwa cha kusapezeka kwa ma enzyme m'matumbo.
Nthawi zambiri kapamba wosakwanira samatulutsa mahomoni, ndiye kuti, samakwaniritsa gawo lachiwiri la zomwe amafunikira thupi. Poyerekeza ndi kusapezeka kapena kuchuluka kwa insulin, matenda a shuga amakula.
Odwala omwe amasowa mavitamini osungunuka ndi michere ina amakhala ofooka. Ntchito zoteteza thupi sizitha kuthana ndi matenda (chimfine, SARS, matenda apakhungu). Mankhwala othandizira pancreas osakhazikika amachitika ndi kukonzekera kwa enzymatic. Zinthu zina zofunika zimayambitsidwanso (insulin, mavitamini).
Matenda enanso omwe madzi ammimbamo samapitilira monga momwe amafunira ndi chifukwa chakuti sangathe kutuluka m'matumba ang'onoang'ono momwe amapangidwira. Theology ya cystic fibrosis ya kapamba imatha kubereka kapena kutenga. M'moyo wonse, izi zimachitika chifukwa mandimu amakhala wonenepa kwambiri. Sangadutse mu ndulu zopyapyala ndikuzipaka pamodzi.
Ennthesized Enzymes
Kutenga kwa enzyme kwenikweni ndikosiyana. Pa pachimake kapamba, wodwalayo amamulembera kudya kwambiri kwa masiku angapo, nthawi zina mpaka milungu iwiri. Pakadali pano, wodwalayo amapaka jakisoni wa michere njira yake. Ndikofunikira kuti muchepetse kutupa ndi kutupa kwa kapamba. Ikani mankhwala omwe amachepetsa zinsinsi za thupi (Mexicoidol, Pantripin, Sandostatin).
Mu chifuwa chachikulu, makonzedwe a enzymatic amagwiritsidwa ntchito omwe angapangitse kuchepa kwa othandizira amitundumitundu (mathamangitsidwe):
Mankhwala amagwiritsidwa ntchito motsutsana ndi maziko a kuphatikizidwa kwathunthu kwa mowa ndikutsatira kwambiri zakudya zomwe zili ndi mapuloteni okhala ndi zakudya zambiri. Mapulogalamu azapuloteni amafunikira ngati chida chomanga cha ziwopsezo za zikondamoyo, kuphatikizapo.
Mlingo woyenera wa mankhwalawa amasankhidwa ndi dokotala payekha, kutengera zotsatira za mayeso, zomwe wodwala akuonetsa. Chidziwitso chofunikira ndichakuti ma enzyme omwe amapezeka m'mabotolo kapena mapiritsi amapota. Zimateteza kwathunthu mankhwalawa kuti asawonongedwe m'mimba. Zovalazi sizingawonongeke, kutafuna kapisolo kapena piritsi. Chidachi chimafikira chilengedwe m'matumbo, chimagwira ntchito yake.
Zomwe zimachitika pakumwa mankhwala ndizoti zimagwiritsidwanso ntchito pakudya kapena, nthawi zina, zitatha. Amatsukidwa ndimadzimadzi ambiri, koma osati amchere (madzi wamba kapena timadziti ta zipatso). Contraind zingaphatikizire tsankho la munthu pa mankhwalawa, momwe thupi lawo siligwirizana. Odwala omwe ali ndi gastritis amamva kupweteka kwam'mimba panthawi ya chithandizo.
Kupewa kwamatenda ndiko kusiya kusuta, mitundu yake yonse (kungokhala, yogwira, panthawi yoyembekezera), mowa wamphamvu. Pathology imayamba chifukwa cha kufa kwa gawo lalikulu la maselo omwe amapanga madzi a pancreatic. Kuzindikiritsa kwakanthawi kumathandizira kumayambiriro kwa chitukuko cha kusakhazikika kwina kokwanira kuti kubwezeretsa kwathunthu kapena pang'ono pang'onopang'ono ntchito ya michere, anthu omwe ali ndi matenda obadwa nawo kuti akhale ndi thanzi labwino mthupi.
Mitundu ya Enzymatic Kukwanira
Pancreatic enzyme akusowa zingachitike pazifukwa zingapo.
Kutengera zifukwa zomwe zinayambitsa kukhazikitsa matenda, pali mitundu ingapo ya kulephera.
Mtundu uliwonse wamatenda umakhala ndi zomwe umayambitsa ndi zomwe zimayambitsa. Kudziwa zomwe zimayambitsa kuphwanyidwa ndikusankha njira yamankhwala.
Madokotala amasiyanitsa mitundu inayi ya kusowa kwa enzymatic:
- exocrine
- endocrine
- enzyme
- exocrine.
Zambiri zomwe zimapangitsa kukhazikika kwa matenda a m'matumbo ndi izi:
- Kuphwanya kukhulupirika kwa minyewa.
- Maonekedwe m'thupi la kuchepa kwama mavitamini ofunika.
- Kutsitsa mapuloteni m'mwazi seramu.
- Anachepetsa hemoglobin m'magazi.
- Kuledzera kwa zakudya zomwe sizilola kudzaza mokwanira zosowa za michere komanso kumwa kwambiri zonunkhira komanso mafuta.
- Kukhalapo kwa cholowa chamtsogolo ku chitukuko chamthupi la zovuta zomwe zimakhudzana ndi ntchito ya thupi.
Kutengera ndi momwe zinthu ziliri, zifukwa zingapo zimayambitsa zomwe zikuwoneka ngati vuto la matenda.
Zizindikiro zodziwika bwino zamitundu yonse ya kusakwanira ndizovuta m'matumbo am'mimba.
Zizindikiro, zoyambitsa ndi chithandizo cha kulephera kwa exocrine
Kuperewera kwa procrine ndikosakwanira kupanga timadziti timene timakhudzana ndi chimbudzi.
Nthawi zambiri, zomwe zimayambitsa kuphwanyidwa kotereku ndimavuto pogwira ntchito m'mimba. Mavuto m'mimba am'mimba amapangidwa ndi matenda am'mimba, matumbo, chikhodzodzo.
Kuphatikiza apo, kugwiritsa ntchito mankhwala osokoneza bongo osiyanasiyana kumabweretsa mavuto ngati amenewa, zomwe zimapangitsa kuti pakhale kusakhazikika kwa thupi ndi michere komanso kufunitsitsa kumwa zakumwa zoledzeretsa.
Kuperewera kwa enocrme ya pokerreatic pancreatic kumadziwika ndi zizindikiro zotsatirazi:
- ukufalikira
- phokoso mokhumudwa
- maonekedwe akumva kuwawa m'mimba,
- kumverera kwa nseru
- kuphwanya chimbudzi cha chakudya.
Sizingatheke kuzindikira bwino lomwe pazizindikiro zomwe zadziwika. Kuti mumvetse bwino mtundu wa kusakwanira ndikuwona momwe mankhwalawo amathandizira, mapangidwe athunthu a maphunziro a labotale amafunikira.
Kuti mudziwe bwino mtundu wa matenda, mayeso otsatirawa ayenera kuchitika:
- kuyezetsa magazi konse.
- Kuyesa kwa magazi pazomwe zili ndi shuga.
Kuchita mayeso amwazi wa shuga ndizovomerezeka, chifukwa kupezeka kwamtundu wanthawi zambiri kumeneku kumakhudzana kwambiri ndi kukula kwa matenda osokoneza bongo m'thupi la wodwala.
Chithandizo cha kuperewera kwa procrine chimachitika powona chakudya chapadera, kupatula mowa ku chakudya, kupatsa thanzi zakudya zamagulu omwe ali ndi mavitamini A, C, E.
Kuphatikiza apo, chithandizo chimafunika pomwa mankhwala apadera omwe amathandizira kupanga ma enzyme.
Zizindikiro, zoyambitsa ndi chithandizo cha exocrine kusakwanira
Kuperewera kwa chinsinsi chakunja kumadziwika ndi kusowa kwa ma enzyme chifukwa chogwira ntchito moyenera m'matumbo ndi kuchepa kwazomwe zimachitika m'zigawo za chakudya.
Izi zimachitika chifukwa chotukuka kwa ma pathologies pomwe kuchuluka kwa maselo am'mimba mwa ziwalo zomwe zimayambitsa kupendekera kumachepa.
Chizindikiro chachikulu cha kuphwanya koteroko ndi ndewu za mushy zomwe zimakhala ndizambiri zamafuta ndi mawonekedwe a mafuta a sheen.
Kuphatikiza apo, chisokonezo chotere mu zikondamoyo za munthu wamkulu chimayendera limodzi ndi mawonekedwe a zotsatirazi:
- chisangalalo
- colic
- kupuma movutikira
- agwiritse
- pamakhala kumva kuwawa m'mimba,
- njira zophatikizana zasokonekera
- khungu louma limawoneka
- pali kukana kwamafuta ndi zonunkhira,
- tachycardia kumakula,
- kupweteka kwa mafupa kumachitika.
Zomwe zimayambitsa kuphwanya izi zitha kukhala kuchepa kwa chiwerengero cha maselo otuluka komanso kuchepa kwa ma enzymes opangidwa ndi chitsulo pakugaya.
Njira zochiritsira pamene zotere zimachitika ndikuwongolera zakudya. Ndikulimbikitsidwa kugwiritsa ntchito njira yokhotakhota pazakudya, zakudya zimayenera kumwa pafupipafupi, koma m'magawo ang'onoang'ono. Kuletsedwa kwamafuta ndi zakudya za zonunkhira kumayambitsidwa, kudya nyama ndi nsomba ndizochepa .Zinthu zanyama zomwe zimagwiritsidwa ntchito muzakudya ziyenera kukhala ndi mafuta ochepa, mkaka womwe umagwiritsidwa ntchito pazakudya uyenera kukhala ndi mafuta ochepa.
Chilolezo chimakhazikitsidwa pakudya chakudya chamadzulo ndi usiku, munthawi imeneyi, dongosolo la kugaya chakudya liyenera kupuma kwathunthu. Mowa ndi mtundu uwu wa matenda ayenera kupatula kwathunthu kuchokera kuzakudya.
Ndikulimbikitsidwa kudya zakudya zam'mera zambiri, zipatso ndi ndiwo zamasamba. Ndi vuto lamtunduwu, chisamaliro chapadera chimayenera kulipidwa pazochuluka zamafuta omwe amwedwa. Kuti muchepetse kuchuluka kwa kupanga kwa mpweya, ndikofunikira kuti mugwiritse ntchito mankhwala monga Mezim ndi Creon.
Kuchita bwino kwa mankhwalawa kumapangitsa kuti chakudya chikhale ndi mphamvu, monga momwe zimapangidwira pakupanga ndowe zabwino komanso kugwira ntchito bwino kwa pulogalamu.
Zizindikiro, zoyambitsa ndi chithandizo cha kuperewera kwa pancreatic enzyme
Ma Enzymes ophatikizidwa ndi maselo a organ ndiyo amachititsa kuti chakudya chizilowa m'thupi. Zikachitika kuti chiwerengero chawo chichepe, kufooka kwa pancreatic kumayamba. Pali zifukwa zingapo zowonekera kwa matenda amtunduwu.
Zomwe zimayambitsa matenda a pathological ndi awa:
- Zotsatira zoyipa za gland ya mankhwala omwe amagwiritsidwa ntchito pochiza matenda ena m'thupi.
- Kukula kwa matenda opatsirana mthupi.
- Pathology mu kapangidwe ndi kapangidwe ka duct.
- Kubadwa kwatsopano kwa chiwalo.
- Kukula kwa dysbiosis m'thupi la wodwalayo.
Mukazindikira matenda amtunduwu, zizindikiro zotsatirazi zimawululidwa:
- munthu ali ndi zofooka komanso ulesi,
- mapangidwe achilendo amadzimadzi okhala ndi fungo losasangalatsa,
- kuchepa kwa chakudya,
- Kupanga kwamphamvu kwa mpweya kumachitika
- wodwala amachepetsa thupi
- kumakhala kupweteka kokhazikika,
- munthu amakhala ndi mawonekedwe opweteka m'mimba.
Njira zotsatirazi zoyezetsera zimagwiritsidwa ntchito pofufuza mtundu wamtunduwu mu kapamba:
- Kuyesa kwa magazi.
- Kusanthula kwamaganizidwe.
- Urinalysis
- Yogwirizana tomography ya limba.
- Ultrasound kuwunika kwam'mimba ziwalo.
Popanga matenda a pathology, mankhwala apadera amagwiritsidwa ntchito omwe angapangitse kuti chimbudzi chikhale. Ndi matenda oterewa, timalimbikitsidwanso kuti tizitsatira zakudya zapamwamba zopatsa mphamvu.
Zizindikiro, zoyambitsa ndi chithandizo cha endocrine pancreatic insuffence
Kukwaniritsidwa kwa Endocrine nthawi zambiri kumachitika chifukwa cha kuvulala kwakumunthu komwe kumakhudza kapamba, komanso kupezeka kwa zotumphukira zotulutsa ziwalo.
Vuto la kuwonongeka kwa minofu ya minyewa yomwe imayambitsa kupezeka kwa lipocaine, insulin ndi glucagon, kuthekera kwakukulu kokhala mtundu woyamba wa matenda a shuga m'thupi kumawonekera.
Pali zisonyezo zingapo zamtunduwu wamatenda.
Zomwe zikuluzikulu ndi:
- Maonekedwe akusanza
- kupezeka kwa mpweya wokhumudwitsa komanso kutsegula m'mimba,
- kusowa kwamadzi
- kukula kwa matenda otsegula m'mimba,
- kuchuluka kwamatumbo
- mawonekedwe a kutupa.
Mukamayesa magazi, kupatuka kowala kuchokera ku chizolowezi kumapezeka. Kuphatikiza pa kugwiritsira ntchito kuyezetsa wamagazi ndi ambiri, kuwunikira kumapangidwa kwa mahomoni apanchipisidi ndi zomwe zili ndi shuga mu plasma.
Njira zoyeserera zovomerezeka kuti zizindikire izi ndi za ultrasound, zowerengera za m'maganizo, kuwunika kwa pulogalamu yolemba ndi urinalysis.
Chithandizo cha vutoli ndikuwongolera mwamphamvu kuchuluka kwa shuga mthupi pogwiritsa ntchito zakudya zapadera. Ngati ndi kotheka, ngati kudya zakudya sikokwanira kusunga shuga m'magazi, chikhalidwe chimagwiritsa ntchito mankhwala apadera a hypoglycemic ndi insulin.
Kuperewera kwa kapamba kukufotokozedwa mu kanema munkhaniyi.