Momwe mungagwiritsire Humulin: Malangizo ogwiritsira ntchito komanso analimbikitsa

Kufotokozera kogwirizana ndi 29.04.2015

• Dzina lachi Latin: Humulin pafupipafupi
• Code ya ATX: A10AB01
• Chithandizo: Mtundu wa insulin wopangidwa mwa mtundu wa insulin
• Wopanga: Eli Lilly East S.A. (Switzerland)

1 ml yankho limaphatikizapo 100 IU mobwerezabwereza insulin ya anthu - yogwira pophika.

Zosakaniza Zocheperako: Metacresol, Hydrochloric Acid, glycerol, madzi d / i, sodium hydroxide.

Pharmacodynamics ndi pharmacokinetics

Mankhwala Humulin Regular (Humulin P) ndi yochepa kuchita insulin. Zotsatira zazikulu zimawonetsedwa ndi kuchepa kwa plasma kuchuluka kwa shuga, mwa kulimbitsa intracellular transportkuchuluka kulowetsa minofu ndi kunyengererakukwera glycogenogenesis, lipojiaisreplication protein, yafupika kupanga shuga chiwindi (kuchepa kwa kuvunda glycogen), etc.

Ndi sc makonzedwe, kuyamba kwa ntchito insulin Humulin Yokhazikika imawonedwa pambuyo pa mphindi 20-30, imapeza bwino kwa maola 1-3 ndipo imagwira ntchito kwa maola 5-8. Kutalika kwa nthawi kumatsimikiziridwa ndi mlingo wa mankhwalawo, malo ndi njira yomwe kayendetsedwe kake kamasiyanasiyana ndipo zimasiyana mosiyanasiyana kutengera umunthu wake.

Kukwana kwa mayamwidwe alinso abwino ndipo zimatengera mlingo, njira jekeseni (v / m, s / c), dera loyang'anira (matako, ntchafu, pamimba, phewa), okhutira insulin mu mankhwala, etc. Insulin imagawidwa mosiyanasiyana mu minofu, samalowa chotchingandipo sichimasiyana ndi mkaka wa amayi. Amachotsa impso.

Zizindikiro zogwiritsidwa ntchito

Zisonyezo za ntchito za insulin Humulin matenda ashuga Mtundu woyamba, komanso mtundu wachiwiri ndi:

• wopanda tsankho kukana Hypoglycemic mankhwala akumwa pakamwa (zovuta mankhwala),
• payekha kukana Hypoglycemic mankhwala opaka pakamwa,
• matenda ashuga ketoacidosis,
• matenda ashugakupangika nthawi wa mimba (ngati alephera zakudya mankhwala),
• hyperosmolar ndi ketoacidotic chikomokere,
• matenda ndi malungo (ndi matenda ashuga pa ntchito zaposachedwa),
• kagayidwe kachakudya matenda
• kubadwakuvulala machitidwe (pokonzekera wodwalayo matenda ashuga),
• kusintha kwa kupitiliza mankhwala insulin kuposa kotalika.

Zotsatira zoyipa

• hypoglycemic chikomokere, hypoglycemia,
• matupi awo sagwirizanakupuma movutikira, urticaria, malungokutsitsa magazi, angioedema),
• matenda ashuga acidosis ndi hyperglycemia (motsutsana ndi kumbuyo kwa matenda ndi kutentha thupi, jakisoni wosaiwalika, milingo yochepa, kuphwanya zakudya),
• kuwonongeka kwamaso (kumachitika koyambirira kwamankhwala ndipo kumakhala kwakanthawi),
• chikumbumtima (ndi zotheka zabwino ndi comatose mkhalidwe)
• mtanda zochita ku insulin yamunthuzachikhalidwe
• lipodystrophykuyabwa Hyperemia m'mawu oyambitsa,
• kuchuluka kwachuma anti-insulin antibodies ndi mapangidwe ena glycemia.

Malangizo ogwiritsira ntchito (Njira ndi Mlingo)

Malangizo a Humulin pafupipafupi amaphatikizapo kusankha kwa payekha ndi mtundu wa makonzedwe malinga ndi plasma kuchuluka kwa shuga, madigiri a glucosuria ndi chikhalidwe cha matendawa.

Insulin jakisoni amalimbikitsidwa kwa mphindi 15-30 musanadye kapena maola awiri atatha.

Lolani kutumikiridwa kwa mankhwala s / c, i / m ndipo ngakhale i / v, nthawi zambiri amathandizira jekeseni wa s / c.

Pa opaleshoni, wodwala matenda ashuga ndi matenda ashuga ketoacidosis yambirani ku / m kapena / njira yoyendetsera.

Kuchulukitsa kwa kuyambitsa insulin Humulin Wokhazikika mukagwiritsidwa ntchito mu monotherapy, monga lamulo - katatu mu maola 24 (ngati kuli kotheka, makonzedwe a nthawi za 5-6 ndi otheka. Malowo lipodystrophysinthani nthawi iliyonse.

Mlingo wa anthu akuluakulu tsiku lililonse nthawi zambiri umakhala magawo 30-40. Ana, nthawi zambiri, amalimbikitsidwa kuti ayambe kulandira chithandizo cha mankhwalawa 8 m'maola 24, pambuyo pake amawasamutsira muyeso wa tsiku ndi tsiku wama 30-40 kapena 0,5-1 / kg. Zilonda zimachitika ndi pafupipafupi maulendo 1-3 (mwina nthawi 5-6).

Pofuna kupitirira mlingo wa tsiku lililonse wa 0,6 PESCES / kg, jakisoni ndi ofunika insulin kawiri kapena kangapo konse m'malo osiyanasiyana mthupi.

Kuphatikiza kwa Humulin Wokhazikika ndi insulin kuposakukhudzika nthawi yayitali.

Kupeza yankho insulin Chotsani kapu ya aluminiyamu pamalopo, pukuta chopukutira ndi mowa ndikupukutira, pogwiritsa ntchito singano yosalala yomata pa syringe, kuboola poyimitsa ndikudzaza mulingo woyenera insulin.

Mukamagwiritsa ntchito makatoniji, kuti mupeze jakisoni woyenera, ndikofunikira kutsatira malangizo a omwe amapanga zolembera.

Bongo

Zizindikiro za bongo zimawerengedwa hypoglycemiazimawonedwa kufookakukopa kwa pakhungu thukuta lozizirakugunda kwa mtima mantha, kunjenjemera, njala, mutu, paresthesia mu miyendo, lilime, milomo. Zothekanso kukokana ndi hypoglycemic chikomokere.

M'malo mwa wofatsa hypoglycemia, wodwalayo, pakudzipatula kwake, ayenera kumwedwa shuga kapena zakudya zomwe zili ndi zopatsa mphamvu mosavuta chakudya.

Pakakhala zizindikiro zowopsa, i / m kapena i / v kasamalidwe akuwonetsedwa glucagon kapena iv jakisoni wa yankho dextrose. At hypoglycemic chikomokere vomereza jekeseni wa iv 20-100 ml 40% dextrosempaka wodwalayo atachoka chikomokere.

Kuchita

Mankhwala osagwirizana ndi mayankho a mankhwala ena.

Somatropinglucagon kulera kwamlomoglucocorticoids, estrogens, BMKK, loop ndi thiazide okodzetsa, Heparinmahomoni a chithokomiro Sulfinpyrazone, sympathomimetics, mankhwala antidepressants, Danazol, Clonidine, Diazoxideodana ndi calcium Morphinechikonga chamba, phenytoinblockers a H1-histamine receptors, Epinephrine muchepetse kugwira ntchito kwa hypoglycemic insulin.

Pentamidine, Reserpinebeta blockers, Octreotide itha kufooketsa kapena kuwonjezera zotsatira za hypoglycemic za mankhwalawa.

Malangizo apadera

Panthawi yofikira yankho, kuoneka ngati matope kapena matupi achilendo, kugwiritsa ntchito mankhwalawa sikuloledwa.

Dziwitsani insulin zotheka pamene yankho lafika kuchipinda kutentha.

Kufunika kwa kusintha kwa mankhwalawa kumachitika zopatsirana matenda Matenda a Addisonmatenda chithokomiro, hypopituitarism, kulepheraimpso Ndi zaka zopitilira 65 (ndi matenda ashuga).

Zinthu zachitukuko hypoglycemia mkhalapakati: bongo wa insulin, zosiyidwa mu mankhwala, mankhwala, kusanzakupsinjika kwakuthupi kutsegula m'mimbamatenda amachepetsa insulin kufuna (kuthamanga matenda a chiwindi ndi impsomwachidule zodabwisakhungwa gren adrenal, chithokomiro England, kulumikizana ndi mankhwala, kusintha kwa jekeseni.

Kutsika kudadziwika glucose wa plasma posintha nyama insulin pa munthu insulin Kusintha koteroko kuyenera kukhala koyenera nthawi zonse kumayang'aniridwa ndi adokotala.

Kukonzekera kwamtsogolo kwa hypoglycemia zitha kuwononga mphamvu yake yoyendetsa galimoto ndikugwira ntchito yoyipa kapena yolondola.

Hypoglycemia Ofatsa atha kuyimitsidwa pawokha, omwe odwala amalimbikitsidwa kuti azinyamula nthawi zonse shuga (osachepera 20 g) ndi chizindikiro choyambirira cha hypoglycemia, tengani pakamwa. Pazomwe zidachitika hypoglycemia Onetsetsani kuti mwamuwuza dokotala kuti athetse kusintha kwa mlingo.

Pa mankhwala insulin ndi zochitika zazifupi nthawi zochepa zomwe zalembedwa lipodystrophy (kuchuluka kapena kuchepa kwa minofu ya adipose) m'dera la jakisoni. Izi zitha kupewedwa ndi masamba omwe amasinthidwa pafupipafupi.

Odwala omwe amagwiritsa ntchito mankhwala opitilira 100 a IU m'maola 24, pakumuchotsa insulin ayenera kuchipatala.

• Actrapid MS,
• Insulin MK,
• Apidra,
• Monosuinsulin (MK, MP),
• Pensulin (SR, Czech Republic),
• NovoRapid,
• Chichewa,
• Humodar R.

• Actrapid NM,
• Vozulim-R,
• Biosulin P,
• Gansulin r,
• Rinsulin P,
• Insuran P,
• Rosinsulin P,
• Humodar R 100 Mitsinje,
• Monoinsulin CR.

Humulin Wokhazikika amaperekedwa kwa ana, poyerekeza ndi milingo yolimbikitsidwa.

Mimba (ndi mkaka wa m'mawere)

At wa mimba ndikofunikira kuganizira kuchepa (I trimester) kapena kuwonjezeka (II-III trimesters) mu insulin. Pambuyo pake kubala mwanamonga nthawi yawo, panali kuchepa kwakukulu kwa zofunikira za insulin.

Poyamba yoyamwitsa, kwa miyezi ingapo, kuyang'anira mkhalidwe wa namwino ndikofunikira, mpaka kukhazikika kwa kufunika kwa insulin.

Ndemanga za insulin Humulin pafupipafupi siochulukirapo, koma yabwino. Mankhwalawa amathana bwino ndi zovuta zowawa (malinga ndi mawonekedwe) a mankhwalawo, zomwe zidapangidwa. Zilibe zoyambitsa zowopsa kapena zowopsa, kupatula pazochitika Hypersensitivity kwa zosakaniza ndi bongo.

Chifukwa chake ngati dokotala akuwona kuti ndizoyenera kugwiritsa ntchito izi insulinHumulin Nthawi zonse amawonetsa zotsatira zabwino zamankhwala.

Njira yogwiritsira ntchito

Mankhwala omwe akufunsidwa amaperekedwa kuti aphwanye digestibility ya chakudya chamitundu yoyamba ndi yachiwiri.

Monga lamulo, kugwiritsa ntchito Humulin makamaka pakulimbana kwa mankhwala a hypoglycemic omwe cholinga chake ndi pakamwa.

Humulin imalimbikitsidwanso ketoacidosis, ketoacidotic ndi hyperosmolar coma, vuto la endocrine lomwe limadziwika ndi kugaya bwino zakudya zamafuta, zomwe zimawoneka nthawi yapakati (ndi kusakwanira kwathunthu kwa zakudya zapadera). Ndikofunikira kwa odwala matenda ashuga, omwe adayamba chifukwa cha matenda opatsirana.

Ndikofunika kudziwa kuti kayendetsedwe ka subcutaneous imachitika m'chigawo cha kutsogolo, mwendo wapamwamba, matako kapena pamimba. Tsamba la jakisoni lifunika kusinthidwa nthawi zonse.

Pankhani ya njira yogwiritsira ntchito Humulin, mlingo ndi njira yogwiritsira ntchito zimatsimikiziridwa payekhapayekha kwa wodwala aliyense. Mulimonsemo, kutengera ndi kukhalapo kwa shuga m'magazi musanadye ndi mphindi makumi asanu ndi limodzi pambuyo pake, kuchuluka kofunikira kwa mankhwalawa kumasankhidwa. Zofunikanso kwambiri ndi kuchuluka kwa glucosuria ndi mawonekedwe a matendawa.

Mankhwala nthawi zambiri amaperekedwa pansi pa khungu kapena intramuscularly. Jakisoni ayenera kuchitidwa theka la ola musanadye mwachindunji.

Kwenikweni, anthu ambiri amakonda njira yotsogolera.

Pamaso pa matenda a shuga a ketoacidosis kapena odwala matenda ashuga, Humulin imatha kutumikiridwa kudzera m'mitsempha kapena intramuscularly. Izi zimagwiranso ntchito pa nthawi ya opaleshoni.

Monga lamulo, dokotala amasankha mtundu wa Humulin. Nthawi zambiri, akatswiri amapereka mankhwala a insulin, omwe amachokera pa kugwiritsa ntchito mankhwala amodzi. Tiyenera kudziwa kuti Humulin pafupipafupi amaloledwa kuperekedwa ngakhale popanda mitundu ina ya insulin. Muthanso kugwiritsa ntchito jakisoni ambiri tsiku lililonse.

Humulin NPH, Humulin L, Humulin Ultralente itha kugwiritsidwa ntchito ngati jakisoni popanda mitundu ina ya ma pancreatic hormone. Zokwanira kawiri pa tsiku.

Chithandizo chamankhwala angapo opangidwa ndi insulin ndikuti, ngati kuli kotheka, kuphatikiza kwa mankhwala omwe amafunsidwa ndi mankhwala ofananawo ndikotheka. Mukaphatikiza zigawozo, ndikofunikira kukumbukira kuti insulini yocheperako ndiyofunika kukokedwa mu syringe yoyamba.

Koma ndalama zomwe zimachokera ku gulu la Humulin M zimawonedwa ngati zosavuta kugwiritsa ntchito. Jakisoni awiri a mankhwalawa ndi okwanira patsiku.

Monga lamulo, kwa makonzedwe aliwonse, mlingo sayenera kupitirira 40 magawo.

Kusintha kuchokera ku zinthu zina zomwe zimakhala ndi insulin kumafuna njira yosamala.

Posamutsa odwala ena amshuga kuchokera ku insulin ya nyama kupita ku Humulin, kuchepetsedwa kwakukulu kwa mlingo woyambirira kapena ngakhale kusintha kwa chiŵerengero cha mankhwala a kuthekera kosiyanasiyana kungafunike.

Kuchepetsa kuchuluka kwa insulini kungachitike mwachangu kapena motsatana. Nthawi zambiri njira yachiwiri imatenga milungu ingapo. Kuchepa kwa kuchepa kwa shuga m'magazi a seramu pakusintha kuchoka ku mtundu wina wa insulin kupita kwina ndikotsika kwambiri. Izi ndizothandiza pokhapokha ngati mlingo wa tsiku ndi tsiku ukhale wochepera 40.

Kusintha kuchokera ku mtundu wina wa mankhwala kupita kwa ena mwa odwala a endocrinologists omwe amalandila insulini yokhayo tsiku lililonse yomwe ili yopitilira 100, ikuyenera kuchitika kuchipatala chokha.

Kufunika kwa insulin kumatha kuwonjezeka panthawi ya matenda opatsirana kapena kupsinjika kwambiri kwamakhalidwe.

Komanso, mlingo wowonjezereka ungafunike pakugwiritsa ntchito mankhwala ena. Mwachitsanzo, munthu akamamwa njira zakulera zam'mlomo, corticosteroids, komanso mahomoni a chithokomiro.

Kufunika kwakanthawi kwa pancreatic mahomoni kumatha kuchepa pamaso pa matenda a msambo wamagulu ndi chiwindi, komanso kumayambiriro kwa mankhwala omwe ali ndi vuto la hypoglycemic. Monga lamulo, omalizirawa akuphatikiza MaO inhibitors komanso BAB yosasankha.

Nthawi zambiri, kukonza insulin tsiku lililonse kungafunike ngati wodwala wayamba kuchita zolimbitsa thupi kapena asintha zakudya zake.

Panthawi yonyamula mwana, kufunika kwa insulin kumayamba kuchepa. Izi zimawonekera bwino nthawi yoyamba ya mimba. Koma njira yowonjezera ya mahomoni a pancreatic ndi yofunika mu trimesters yachiwiri ndi yachitatu.

Zotsatira zoyipa

Matenda a shuga amawopa mankhwalawa, ngati moto!

Muyenera kungolemba ...

Wodwala amatha kukumana ndi mavuto monga:

• urticaria
• angioedema,
• malungo
• kupuma movutikira
• kukakamizidwa kutsikira kufikira kowopsa,
• achina,
• khungu la nkhope, thupi, mikono ndi miyendo,
• zolimbitsa thukuta,
• thukuta
• Kunjenjemera kwa malekezero ake kumtunda ndi kumbuyo,
• chisangalalo
• kuda nkhawa kosalekeza
• paresthesia mkamwa,
• mutu
• kugona
• zosokoneza kwambiri kugona
• mantha
• mavuto
• kusakhazikika
• machitidwe a atypical
• kusatsimikizika kwa mayendedwe
• kusalankhula bwino ndikutha kuwona
• hypoglycemic coma,
• hyperglycemia
• matenda ashuga acidosis.

Chizindikiro chomaliza chimakonda kuwonetsedwa ndi kuyamwa kwa mankhwala ochepa. Zimathanso kuchitika mukaphonya jakisoni wotsatira.

Ndikofunikira kuti muzitsatira zakudya zomwe dokotala wanena. Popeza, ngati chakudyacho sichitsatiridwa, kugona, kuchepa kwa chakudya, komanso kuchepa kwa thupi kumadziwika.

Kuphatikiza pazizindikiro zam'mbali, kuphwanya kwa chikumbumtima kungaganiziridwe, komwe kumadziwonetsera komwe kukuchitika kwa chitukuko cha dziko loyipitsitsa komanso lokoma. Ngakhale wodwala kumayambiriro kwa chithandizo anati edema zingapo ndi mkhutu kuyimitsidwa. Ndikofunika kudziwa kuti zizindikirozi sizogwirizana ndipo zimangotheretu ndi kupitiliza kwa chithandizo chapadera.

Kuyanjana kwa mankhwala osokoneza bongo

Ndizofunikira kudziwa kuti ndizosatheka kugwiritsa ntchito mtundu wamtunduwu pakanthawi ya ma pancreatic hormone ndi hypoglycemia komanso kupezeka kwa hypersensitivity kwa insulin kapena chimodzi mwazinthu zomwe zimagwiritsidwa ntchito pofunsa. Humulin nayonso siyigwirizana ndi mayankho a mankhwala ena.

Mphamvu yake yamphamvu ya hypoglycemic imatheka ndi sulfonamides (kuphatikiza mankhwala a hypoglycemic omwe amapangidwira pakamwa pakamwa).

Komanso, zotsatira zazikulu za mankhwalawa zimatheka ndi mankhwala monga MaO inhibitors (Furazolidone, Procarbazine ndi Selegiline), carbonic anhydrase inhibitors, ACE inhibitors, NSAIDs, anabolic steroids, tetracyclines, Clofibrate, Ketoconazole, Pyridoxine, Chloroquinine.

Kukopa kwakukulu kwa mankhwalawa kumachepetsedwa ndi Glucagon, Somatropin, GCS, njira zakulera zamkati, thiazide ndi loop diuretics, BMCC, mahomoni a chithokomiro, Sulfinpyrazone, sympathomimetics, antidepressants a Clonidine, antagonists, a H1 blocking.

Koma za beta-blockers, monga Reserpine, Octreotide, Pentamidine amatha onse kuchulukitsa ndikuchepetsa zochitika zazikulu za hypoglycemic zomwe zimatengedwa ngati ma pancreatic timalo a munthu.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Chofunika kwambiri pakubala kwa ana ndikusunga shuga wambiri mu seramu yamagazi.

Izi zimangogwira ntchito kwa iwo omwe akuchiritsidwa ndi insulin.

Ndikofunika kukumbukira kuti amayi omwe ali ndi vuto la endocrine ayenera kudziwitsa dokotala za cholinga chawo chokhala ndi mwana. Kuwunikira mosamala kuchuluka kwa shuga m'magazi ndikofunikira kwa amayi onse apakati.

Mwa amayi omwe ali ndi kusokonezeka kwa endocrine panthawi yoyamwitsa, zingakhale zofunikira kukhazikitsa kuchuluka kwa insulin kapena zakudya.

Makanema okhudzana nawo

Malangizo ogwiritsira ntchito ndi kuwunika kwa mankhwala a Humulin mu kanema:

Ndikofunika kukumbukira kuti kusintha kwina kulikonse kwa mtundu kapena mtundu wa mahomoni opanga pancreatic, omwe ali ofanana kwathunthu ndi munthu, ayenera kuchitika moyang'aniridwa ndi adokotala. Palibe chifukwa chomwe mungasankhire nokha mankhwala, chifukwa sangakhale oyenera pamatenda ena. Njira yodziwira bwino chithandizo ingadziteteze ku matenda ashuga.

Gulu la Nosological (ICD-10)

Kutulutsa Fomu

Kuyimitsidwa kwa kayendetsedwe ka subcutaneous, 100 IU / ml. 10 ml ya mankhwalawa osalowa mugalasi Mbale. 1 fl. kuyikidwa mu paketi ya kadikhadi.

3 ml iliyonse kapu yolowerera ndale. Makatoni 5 amaikidwa pachimake. 1 bl. zimayikidwa pabokosi lamakatoni kapena makatoni amaikidwa mu cholembera cha syringe ya QuickPen ™. Ma cholembera asanu a syringe amaikidwa pakatoni.

Wopanga

Yopangidwa ndi: Eli Lilly ndi Company, USA. Lilly Corporate Center, Indianapolis, Indiana 46285, USA.

Atanyamula: ZAO "ORTAT", 157092, Russia, dera la Kostroma, chigawo cha Susaninsky, s. Kumpoto, microdistrict. Kharitonovo.

Cartridges, QuickPen ™ Syringe Pens , yopangidwa ndi Lilly France, France. Zone Industrialiel, 2 ru Colonel Lilly, 67640 Fegersheim, France.

Atanyamula: ZAO "ORTAT", 157092, Russia, dera la Kostroma, chigawo cha Susaninsky, s. Kumpoto, microdistrict. Kharitonovo.

Lilly Pharma LLC ndiye mlendo yekha wa Humulin ® M3 ku Russia Federation

Zotsatira za pharmacological

Humulin NPH ndi munthu yemwe amapanganso insulin.

Chochita chachikulu cha insulin ndi kuphatikiza shuga kagayidwe. Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zosiyanasiyana zamthupi. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa amino acid, koma kuchepa kwa glycogenolysis wa gluconeogeneis, ketogeneis, lipolysis, protein catabolism, ndi kutulutsidwa kwa ma amino acid.

Pharmacokinetics

Humulin NPH ndi insulin yomwe ikukonzekera. Kukhazikika kwa mankhwala ndi ola limodzi pambuyo pa kukonzekera, mphamvu yayikulu imakhala pakati pa maola awiri ndi asanu ndi atatu, kutalika kwa nthawi ndi maola 18-20. Kusiyana kwamwini pantchito ya insulin kumadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi, ndi zina zambiri.

Kukwanira kwathunthu ndi kuyambika kwa mphamvu ya insulin kumadalira malo a jakisoni (m'mimba, ntchafu, matako), mlingo (kuchuluka kwa insulin), kuchuluka kwa insulini mu mankhwalawa, ndi zina. Amawonongedwa ndi insulinase makamaka m'chiwindi ndi impso. Amachotsa impso (30-80%).

Mimba komanso kuyamwa

Pakati pathupi, ndikofunikira kuti pakhale chitetezo chabwino kwa odwala omwe amalandila insulin (omwe amadalira insulin kapena matenda a shuga). Kufunika kwa insulin nthawi zambiri kumachepetsa panthawi yoyambirira ndikuwonjezeka panthawi yachiwiri komanso yachitatu. Nthawi yobadwa pambuyo pokhapokha ndipo mwayamba kubadwa, zofunika za insulin zimatha kugwa kwambiri. Odwala omwe ali ndi matenda ashuga amalangizidwa kuti azidziwitse dokotala wawo za kubereka kapena kukonzekera pakati.

Odwala omwe ali ndi matenda a shuga mellitus nthawi yoyamwitsa angafunikire kusintha mlingo wa insulin, zakudya, kapena zonse ziwiri.

Zotsatira zoyipa

Thupi lawo siligwirizana: Odwala amatha kuona matupi awo sagwirizana ndi mawonekedwe ofiira, kutupa, kapena kuyunkhira pamalo a jakisoni. Izi zimachitika pakatha masiku angapo mpaka milungu ingapo. Nthawi zina, izi zimachitika chifukwa cha zifukwa zosakhudzana ndi insulin, mwachitsanzo, mkwiyo pakhungu ndi wothandizira kuyeretsa kapena jakisoni wosayenera. Zotsatira zoyipa zamagetsi zomwe zimachitika chifukwa cha insulin zimachitika kangapo, koma zimakhala zazikulu kwambiri. Amatha kuwonetsedwa ndi kuyabwa kwakukulu, kupuma movutikira, kufupika, kuchepa kwa magazi, kuchuluka kwa mtima, komanso thukuta kwambiri. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo. Nthawi zina mankhwalawa amakumana ndi Humulin NPH, chithandizo chofunikira chimafunikira. Mungafunike kusintha kwa insulin, kapena kutsimikiza mtima.

Lipodystrophy imatha kupezeka pamalo a jakisoni.

Zolemba zogwiritsira ntchito

Kusamutsa wodwala kupita ku mtundu wina kapena kukonzekera kwa insulin ndi dzina lina lamalonda kuyenera kuchitika moyang'aniridwa ndi achipatala. Kusintha kwa zochitika, mtundu (wopanga), mtundu (Wokhazikika, M3, insulin ya nyama) kungayambitse kusintha kwa mlingo.

Kwa odwala ena, kusintha kwa mlingo kumakhala kofunikira pakusintha kuchokera ku insulin yochokera ku nyama kupita ku insulin ya anthu. Izi zitha kuchitika kale poyambilira kukonzekera kwa insulin ya anthu kapena pang'onopang'ono pakangotha ​​milungu ingapo kapena miyezi ingapo atasamutsidwa. Zizindikiro zakutsogolo kwa hypoglycemia panthawi ya insulin yaumwini mwa odwala ena akhoza kutchulidwa kochepa kapena zosiyana ndi zomwe zimawonedwa panthawi ya insulin ya nyama. Ndi kusintha kwa matenda a shuga m'magazi, mwachitsanzo, chifukwa cha insulin yokwanira, zonse kapena zina mwazizindikiro zomwe zimayambitsa hypoglycemia zimatha, zomwe odwala ayenera kudziwitsidwa. Zizindikiro zakutsogolo kwa hypoglycemia zimatha kusintha kapena kusalankhula pang'ono ndi matenda oopsa a shuga, matenda ashuga a m'mimba kapena chithandizo cha mankhwala monga beta-blockers. Kuyankha molakwika kwa hypoglycemia kapena hyperglycemia kumatha kuchititsa kuti musakhale ndi chikumbumtima, chikomokere, kapena kufa. Mlingo wosakwanira kapena kusiya kulandira chithandizo, makamaka odwala matenda a shuga omwe amadalira matenda a shuga, angayambitse matenda a hyperglycemia ndi matenda ashuga a ketoacidosis (mikhalidwe yomwe ikhoza kukhala yowopsa kwa wodwalayo).

Kuchiza ndi insulin yaumunthu kungayambitse kupanga ma antibodies, koma ma antibody titers ndi otsika kuposa motsutsana ndi insulin yanyama yoyeretsedwa.

Kufunika kwa insulini kumatha kuchepa ndi kusakwanira kwa adrenal gland, gland planditary kapena chithokomiro, ndi aimpso kapena kwa chiwindi.

Ndi matenda ena kapena kupsinjika kwamalingaliro, kufunikira kwa insulin kungakulitse.

Kuwongolera mlingo wa insulin kungafunikenso ndi kuchuluka kwa zochitika zolimbitsa thupi kapena kusintha kwa zakudya zomwe mumakonda.

Ngati thiazolidinediones amagwiritsidwa ntchito limodzi ndi insulin, chiopsezo chokhala ndi edema ndi mtima kulephera chikuwonjezeka, makamaka kwa odwala omwe ali ndi matenda a mtima.

Njira zopewera kupewa ngozi

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Pa hypoglycemia, wodwalayo amatha kuchepa ndende komanso kuthamanga kwa zochitika zama psychomotor. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa amafunikira makamaka (mwachitsanzo, kuyendetsa galimoto kapena makina ogwiritsa ntchito).

Odwala ayenera kulangizidwa kuti azisamala kuti asamayendetse hypoglycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofatsa kapena zosapezekapo zizindikiro, okhazikika a hypoglycemia kapena okhazikika a hypoglycemia. Zikatero, ndikofunikira kuwunika momwe wodwala amayendetsa galimoto.

Humalog ndi chiyani insulin? Kodi ndizitali kapena zazifupi?

Ichi ndi mahomoni a ultrashort, omwe ali othamanga kwambiri. Imayamba kuchita pafupifupi nthawi yomweyo - osapitirira mphindi 15-20 pambuyo pa kubayidwa. Izi ndizothandiza panthawi yomwe muyenera kuzimitsa msanga magazi. Komabe, pakhoza kukhala zovuta mu odwala matenda ashuga omwe amatsatira zakudya zamafuta ochepa. Chifukwa Humalog, yomwe idayambitsidwa chakudya chisanachitike, imayamba kuchita zinthu mwachangu kuposa zakudya zama carb ochepera zomwe zimamwa. Zotsatira zake, shuga wodwala matenda ashuga amatha kutsika kwambiri.

Mwina Humalog ndiye wothamanga kwambiri wamitundu yonse ya insulin. Ngakhale opanga ma analogu omwe amapikisana naye sangavomereze zomwe ananenazi. Ati mankhwala awo a Apidra ndi NovoRapid ayambanso kuchita zinthu mwachangu. Palibe zambiri zenizeni pankhaniyi. Kwa odwala matenda ashuga osiyanasiyana, mitundu yambiri ya insulin imagwira ntchito mosiyanasiyana. Zowona zenizeni zimatha kupezedwa mwa kuyesa ndi zolakwika.

Kodi mungasankhe bwanji mulingo wa Humalog insulin pa mkate mkate (XE)?

Mochulukitsa zakudya zomwe anthu odwala matenda ashuga amapeza, ndiye kuti ayenera kupaka insulin asanadye. Kupereka kwa zakudya zamagalimoto kumatha kuyezedwa m'magawo a mkate kapena magalamu. Kuwerengera kwamawerengero azakudya ndi mtundu wofunikira wa Humalog zimapezeka pano.

Mwazi wanu wamagazi ungakhale wabwino kwambiri ngati mupita zakudya zamafuta ochepa. Sizikupanga nzeru kwa odwala matenda ashuga omwe amatsata izi kuti awerenge chakudya m'magawo a mkate. Chifukwa kudya kwa tsiku ndi tsiku kwamakina osaposa 2,5 XE, komanso kwa ana ochepera.

Dr. Bernstein adalimbikitsa kuwerengera zakudya zamafuta m'magalamu, osati XE. Humalog ndi insulin yolimba yomwe imagwira ntchito mwachangu komanso modzidzimutsa. Sizigwirizana bwino ndi zakudya zamafuta ochepa. Ganizirani kusintha kwa icho kukhala Actrapid.

Ponena za ana, ndizomveka kusinthira mwana wodwala matenda ashuga kuti akhale zakudya zamafuta ochepa, gwiritsani ntchito Actrapid kapena mankhwala ena achidule m'malo mwa Humalog insulin, komanso kukana kugwiritsa ntchito pampu ya insulin. Werengani nkhani ya "Matenda a shuga mu Ana" kuti mumve zambiri.

Kodi zingakwanitse bwanji?

Muyenera kumugaya Humalo katatu patsiku musanadye. Komabe, mlingo ndi ndandanda ya jakisoni wa insulin aliyense wodwala matenda ashuga ayenera kusankhidwa payekhapayekha. Kugwiritsa ntchito mapulani okonzedwa sangapereke chiwongolero chabwino cha matenda a shuga. Werengani mwatsatanetsatane nkhani "Kuwerengera kuchuluka kwa insulin yochepa komanso ya ultrashort musanadye."

Chithandizo cha boma chimalimbikitsa kugwiritsa ntchito Humalog ndi mawonekedwe ake monga insulin yachangu musanadye. Jekeseni zimachitika mphindi 15 musanadye. Komabe, kwa odwala omwe ali ndi matenda amtundu wa 1 komanso amtundu wa 2, omwe amatsata zakudya zamafuta ochepa, ndibwino kuti mupeze insulin yochepa, monga Actrapid, m'malo mwa ultrashort musanadye. Chifukwa kuthamanga kwa kukonzekera kochepa kumayenderana bwino ndi kusinthidwa kwa zinthu zovomerezeka ndi zovomerezeka. Werengani zambiri mu nkhani "Mitundu ya Insulin ndi Zotsatira Zawo".

Humalog mwachangu kuposa mankhwala ena amatha kupangitsa kuti shuga azikhala kwambiri. Chifukwa chake, ndibwino kukhala nanu pokhapokha pachitika ngozi. Komabe, ochepa omwe ali ndi matenda ashuga omwe akufuna kugwiritsa ntchito onse aifupi ndi a insulin. Ngati muthana ndi kagayidwe kakang'ono ka shuga wanu wamafuta ochepa, mungathe kudutsa ndi mankhwala osakhalitsa.

Kodi jakisoni aliyense amatalika bwanji?

Jekeseni aliyense wa mankhwala a Humalog amatha pafupifupi maola anayi. Anthu odwala matenda ashuga omwe amatsata zakudya zama carb ochepa amafunika Mlingo wambiri wa insulin. Nthawi zambiri imayenera kuchepetsedwa kuti ipange jekeseni woyenera wa mankhwala osakwana 0,5-1. Humalog imatha kuchepetsedwa osati kwa ana omwe ali ndi matenda a shuga 1, komanso odwala akuluakulu. Chifukwa ndi mankhwala amphamvu kwambiri. Mukamagwiritsa ntchito mankhwala ochepa, insulin imasiya kugwira ntchito mwachangu kuposa momwe amafunidwira. Mwina jakisoni amatha kumapeto kwa maola awiri ndi awiri ndi awiri.

Pakapita jakisoni iliyonse ya kukonzekera kwa ultrashort, muyezetse magazi osachepera maola atatu pambuyo pake. Chifukwa kufikira nthawi ino, mlingo wa insulin wolandirira ulibe nthawi kuti uwonetse mphamvu yake yonse. Monga lamulo, odwala matenda ashuga amapereka jakisoni wa insulin yofulumira, idyani, kenako kuyeza shuga kale chakudya chotsatira. Kupatula pokhapokha ngati wodwala akumva zizindikiro za hypoglycemia. Zikatero, muyenera kudziwa nthawi yomweyo kuchuluka kwa shuga m'magazi ndipo ngati kuli koyenera, chitanipo kanthu.

Kodi pali kusiyana kotani pakati pa Humalog ndi Humalog Remix?

Prostamine Hagedorn (NPH) yosalowerera ndale, yomwe imachepetsa zochita za insulin, yawonjezeredwa ku Humalog Remix 25 ndi 50. Mitundu ya insulin iyi imasiyana ndi zomwe zili mu NPH. Mowonjezereka mankhwala, kumawonjezera zochita za jakisoni. Mankhwalawa ndi otchuka chifukwa amatha kuchepetsa kuchuluka kwa jakisoni tsiku ndi tsiku, kuchepetsa njira ya insulin. Komabe, sangapereke magazi moyenera. Chifukwa chake, Dr. Bernstein ndi endocrin-patient.com salimbikitsa kugwiritsa ntchito iwo.

Proteni yosagwira nawo mbali ya Hagedorn nthawi zambiri imayambitsa matupi awo sagwirizana ndi mavuto ena. Kuti mumve zambiri, onani nkhani yakuti "Mitundu ya Insulin ndi Zotsatira Zawo". Kugwiritsa ntchito Humalog Remix 25 ndi 50 ndi njira yachindunji yovuta yovuta kwambiri komanso yodwala matenda ashuga. Mitundu ya insulini imeneyi imakhala yoyenera kwa odwala matenda ashuga okalamba okha amene amakhala ndi moyo wocheperako kapena amene ali ndi vuto lotha kuchepa. Magulu ena onse a odwala ayenera kugwiritsa ntchito Humalog yoyera yokha. Ndipo ndibwino kusinthana ndi zakudya zamafuta ochepa ndikuyesa jakisoni wa Actrapid musanadye.

Ndi insulin iti yomwe ili bwino: Humalog kapena NovoRapid?

Pangakhale palibe chidziwitso cholondola choyankha funso ili, lomwe nthawi zambiri limafunsidwa ndi odwala. Chifukwa mitundu yambiri ya insulini imakhudza aliyense wodwala matenda ashuga payekhapayekha. Onse a Humalog ndi NovoRapid ali ndi mafani ambiri. Monga lamulo, odwala amapaka jakisoni mankhwala omwe amapatsidwa kwaulere.

Ziwengo zimakakamiza ena kuti asinthe mtundu wina wa insulin kupita ku wina. Tikubwerezanso kuti ngati mutsatira zakudya zamafuta ochepa, ndibwino kugwiritsa ntchito mankhwala achidule, monga Actrapid, m'malo mwa Humalog, NovoRapid kapena Apidra mwachangu, musanadye. Ngati mukufuna kusankha mitundu yoyenera ya insulin yowonjezera komanso yachangu, ndiye kuti simungathe kuchita popanda kuyesa komanso zolakwika.

Mndandanda wa insulin Humalog (lispro) ndi Apidra (glulisin) ndi NovoRapid (aspart). Kapangidwe ka mamolekyulu awo ndiosiyana, koma pochita nawo zilibe kanthu. Dr. Bernstein akuti Humalog ndi yachangu komanso yamphamvu kuposa anzawo. Komabe, si odwala onse omwe amatsimikizira izi. Pamabwalo a odwala matenda ashuga olankhula Chirasha, mutha kupeza mawu otsutsa.

Odwala omwe ali ndi matenda amtundu wa 1 komanso a 2 omwe amatsatira zakudya zotsika kwambiri amatha kuyesa kulowetsanso insulin lyspro ndi mankhwala osakhalitsa. Mwachitsanzo, pa Actrapid. Pamwambapo zalembedwa mwatsatanetsatane chifukwa chake izi ndizoyenera kuchita. Komanso, insulin yochepa ndiyotsika mtengo. Chifukwa adalowa m'msika zaka zambiri m'mbuyomu.

10 ndemanga pa Humalog

Mwana wathu wazaka 7 watha kudwala matenda ashuga amtundu woyamba. Muli ndi insulin Humalog, kukonzekera kuyamba jekeseni. Chonde fotokozerani kuwerengera Mlingo pochita? Kodi mwana wodwala matenda ashuga ayenera kudya zochuluka motani pa insulin iyi? Ndikumvetsa kuti zonsezi ndi zaumwini, koma pafupifupi. Kodi ndizowona kuti Humalog imayamba kuchita mphindi 10 jekeseni, ndipo nsonga yake imachitika ola 1? Kodi ndibwino kuti muzingozipereka musanadye kaye kapena mutadya? Kodi akuchita zinthu motani koyambirira?

Kodi ndizowona kuti Humalog imayamba kuchita mphindi 10 jekeseni, ndipo nsonga yake imachitika ola 1?

Tsambali limalimbikitsa zakudya zama carb ochepera odwala 1 a shuga. Ndizoyenera ndikulimbikitsidwa osati kwa akulu okha, komanso kwa ana. Anthu odwala matenda ashuga omwe asinthana ndi zakudyazi amafunanso insulin yambiri. Ndipo kwa ana - nthawi zambiri "homeopathic", mwina mayunitsi a 0.25-0,5 nthawi. Zachidziwikire muyenera kuphunzira momwe mungapangire insulin.

Pa Mlingo wocheperako, umayamba kuchita pambuyo pake ndikutha mwachangu kuposa masiku onse. Zambiri zolondola mutha kupeza kuchuluka kwa shuga m'magazi mwa mwana pambuyo pakubayidwa, ndikutsata nthawi. Mwachitsanzo, mutha kubayitsa mayunitsi 0,25 ndikuyang'ana shuga pambuyo 15, 30, 45 ndi 60 Mphindi. Sizokayikitsa kuti mayunitsi a 0.25 adzayamba kugwira ntchito posachedwa kuposa mphindi 15.

Kodi mwana wodwala matenda ashuga ayenera kudya zochuluka motani pa insulin iyi?

Anthu omwe amadwala matenda ashuga pa chakudya chama carb ochepa samawerengera zakudya zawo osati mgawo, koma magalamu

Ndikumvetsa kuti zonsezi ndi zaumwini, koma pafupifupi.

Kwa mwana wazaka 7 kutsatira chakudya chochepa cha carb, ndimayamba jakisoni ndi mayunitsi a 0,25 kenako ndikuwonjezera mlingo pang'onopang'ono ngati pakufunika. Pamwamba kwambiri
kuyambira mlingo kumayambitsa hypoglycemia. Ndikofunika kupewa izi.

Ngati ndi kotheka, ndibwino kugwiritsa ntchito osati ultrashort Humalog, koma insulin yochepa mwachitsanzo, Actrapid.

Kodi ndibwino kuti muzingozipereka musanadye kaye kapena mutadya?

Onani http://endocrin-patient.com/raschet-insulin-eda/. Unikani bwino. Zotsalira sizikudziwika bwino - funsani.

Kodi akuchita zinthu motani koyambirira?

Makamaka kwambiri, chifukwa ndikulimbikitsa kuyambira ndi mayunitsi a 0.25. Itha kukhala 2,5 UNITS ya insulin kuchepetsedwa maulendo 10. Kapenanso ngati mayunitsi 5 ngati akuchepetsedwa 20.

Ndili ndi CD1 wazaka 11, zaka 22, kutalika 177 cm, kulemera makilogalamu 69. Ndikofunikira kusintha kuchokera ku NovoRapid insulin kupita ku Humalog, chifukwa NovoRapid sikuperekedwanso kwaulere. Kodi kuchuluka kwa mankhwalawa kumasinthidwa bwanji pakusintha kotere?

Kodi kuchuluka kwa mankhwalawa kumasinthidwa bwanji pakusintha kotere?

Izi ndi za aliyense payekha kwa wodwala aliyense. Kwa ambiri, mlingo sasintha. Mutha kubaya insulin yatsopano 10-20% yocheperako, ndikuwonjezera mlingo wake ngati pakufunika. Kapenanso yikani mlingo womwewo.

Mwana wazaka 10, SD wamiyezi 7, ankakonda kumuyika Humalog chifukwa adalandira kwaulere, lero adapereka NovoRapid. Kodi ndizowopsa kusintha insulini, womwe umawerengera?

m'mbuyomu anaika Humalog, chifukwa idaperekedwa kwaulere, lero adapereka NovoRapid. Kodi ndizowopsa kusintha insulini, womwe umawerengera?

Monga lamulo, Mlingo wake sasintha, koma zonsezi ndi zokha. Mutha kuyamba kubayirira insulin yatsopano ndi mlingo wa 15-20% m'munsi, kenako ndikuukweza ngati pakufunika.

Zaka 72 zakubadwa. Type 2 shuga. Humalog Remix ya 25 imalembedwa nthawi zonse. Masiku ano, Humalog Mix 50 idapangidwa ndi cholakwika.

Chonde ndiuzeni ngati ndisinthe mlingo

Dr. Bernstein salimbikitsa aliyense kukonzekera kwa insulin, kuphatikiza Humalog Remix.

Ndili ndi zaka 70, mtundu wa matenda ashuga kuyambira 2010. Ndinkamwa mapiritsi osiyanasiyana: shuga, glucovans, gluconorm, etc. shuga pang'onopang'ono idakula. Mapiritsi omaliza a gulu Trazhenta, onglisa. Usiku, ndidabaya mayunitsi a Lantus 16-18. Shuga osungidwa pamndandanda wa 8-10. Tsoka ilo, mavuto akulu adawoneka ndi mafupa, kenako matumbo. Kutengera zowonetsera izi, adotolo adandisunthira kusakaniza kwa 25 kwa 20 mayunitsi 20 m'mawa ndi madzulo. Komabe, shuga idakwera - 14 pamimba yopanda kanthu, itatha maola awiri 15. Mwina ili ndi mlingo wocheperako, ndimayesetsa kudya zakudya zamafuta ochepa. Lantus yathetsedwa. Maganizo, ndikuyembekeza, adzatsogolera kuwunikenso. Zikomo

Tsoka ilo, mavuto akulu adawoneka ndi mafupa, kenako matumbo.

Nkhani wamba ya munthu wodwala matenda ashuga yemwe adalemala chifukwa cha chithandizo chokwanira, ndipo akukonzekera kupita kumanda.