Rosinsulin ndi mankhwala a insulin omwe amagwiritsidwa ntchito m'njira zina za matenda ashuga. Iyenera kutsimikizika nthawi yomweyo kuti pali mitundu ingapo ya mankhwalawa:

• Rosinsulin P – Insulin yochepa ndi kuyamba kwa zotsatira, pambuyo theka la ola kuyambira mphindi yolamulira ndikukula kwakukulu mkati mwa maola 1-3. Kutalika konse kokwanira mpaka maola 8,
• Kusakaniza kwa Rosinsulin M – “Pakati” insulinPokhala magawo awiri (chinthu chopezeka ndi mankhwala komanso chinthu chopanga ma genetic, chofanana ndendende ndi mahomoni amunthu). Zizindikiro zoyambirira za mankhwalawa zimawonekera theka la ola pambuyo pa kuperekedwa, mphamvu yayitali imawonekera kuyambira maola anayi mpaka khumi ndi awiri, ndipo kutalika konse kwa zotulukazo kumachitika pafupifupi tsiku limodzi,
• Rosinsulin C – “Pakati” insulinwopangidwa kwathunthu wa insulin-isophan wopezedwa ndi ma genetic engineering. Mosiyana ndi kusakaniza kwa Rosinsulin M, zotsatira za mankhwalawa zimachitika mkati mwa ola limodzi ndi theka, ndikufika pazokwanira komanso zimakhala - bola ngati mankhwala am'mbuyomu,

Mankhwala ofananawa amafunikira kwa anthu omwe zochita zawo za insulin ndizosakwanira. Izi zimabweretsa kukulira kwa kuchuluka kwa shuga m'magazi, kuphwanya mayamwidwe ake ndi minofu, yomwe imakhala yoopsa kwambiri ndipo imatha kufooketsa thanzi lathu. Odwala omwe ali ndi matenda ashuga, pakumvetsetsa njira zovuta za kagayidwe kazakudya, amaphunzira kuwunika momwe alili (kuyeza pafupipafupi ndi glucometer) ndikugwiritsira ntchito "yayitali", "yapakatikati" kapena "yochepa" kuti athetse.

Mankhwalawa amagwiritsidwa ntchito:

• Insulin yodalira matenda a shuga
• Matenda a shuga osagwirizana ndi insulin (mtundu II), thupi likagonjera mitundu ya mankhwala a hypoglycemic,
• Matenda ashuga ketoacidosis ndi chikomokere,
• Matenda oyambitsidwa ndi pakati,
• Ulamuliro wa shuga kwa odwala omwe akufuna kuchitidwa opaleshoni, kuvulala, kuvutika kwambiri pachimake cha matenda opatsirana - ngati kugwiritsidwa ntchito kwa othandizira ena a hypoglycemic,

Kutulutsa mafomu a Rosinsulin - mayankho ndi kuyimitsidwa kwa jakisoni. Mankhwalawa amathandizidwa ndi mankhwalawa (nthawi zina, kudzera m'mitsempha kapena intramuscularly). Kuchulukitsidwa kwa mankhwalawa kumatithandizanso kudziwa malo omwe jakisoni - Odziwa odziwa bwino amadziwa komwe kuli bwino kubaya insulin m'malo osiyanasiyana. Ndikofunikira nthawi zonse kusintha malo a jakisoni kuti mupewe kuwononga zotsatira za minofu (lipodystrophy, etc.).

Nthawi ya kukhazikitsidwa kwa mankhwala osiyanasiyana ndi yosiyana komanso yolumikizidwa ndi zakudya. Mwachitsanzo, Rosinsulin P "yayifupi" imayikidwa mphindi khumi ndi zisanu mpaka makumi awiri asanadye. Ndipo "pafupifupi" Rosinsulin C, yomwe imagwiritsidwa ntchito kamodzi patsiku, imaperekedwa kwa theka la ola musanadye chakudya cham'mawa. Wodwala aliyense amapanga pulani yake yogwiritsira ntchito ma insulin osiyanasiyana, potengera kuchuluka kwa glucometer pamagazi a magazi, mikhalidwe ya matenda ake ndi moyo wake.

Mankhwala ndi contraindised mu:

• Kusagwirizana ndi chilichonse
• Hypoglycemia,

Amayi oyembekezera komanso oyembekezera amatha ndipo ayenera kutero, ngati pangafunike kugwiritsa ntchito insulin. Ndiotetezeka kwa mwana wosabadwa komanso wakhanda. Koma wodwalayo amayenera kuwonetsetsa kuchuluka kwa shuga, popeza kagayidwe ka shuga kamasiyana kwambiri pakakhala pakati komanso pobereka.

Zotsatira zoyipa ndi bongo

Kusagwirizana ndi mitundu ina ya insulini kumatha kuyambitsa zovuta: kuyambira urticaria, kutentha thupi, kufupika, mpaka angioedema.

Komanso, kukula kwa hypoglycemia ndikotheka, zizindikilo zoyambirira zomwe zimakhala pallor, kunjenjemera, nkhawa, palpitations, ndi zina zotero (werengani zambiri mu nkhani yapadera yokhudza mkhalidwewu). Kuchulukitsa izi, kuchuluka kwa ma anti-insulin omwe ali m'magazi kungakulitse.

Poyamba, chithandizo chimatha kutsagana ndi edema komanso kuwonongeka kwa mawonekedwe. Patsamba la jakisoni, redness, kutupa, kuyabwa, ndi chiwonongeko cha minofu ya adipose ndizotheka (ndi jakisoni pafupipafupi m'dera lomweli).

Mankhwala osokoneza bongo a Rosinsulin amatsogolera ku hypoglycemia ndipo amafuna njira zadzidzidzi - kuchokera pakuwonjezera shuga ndi wodwalayo, kufikitsa mayankho a shuga ndi glucagon (kutayika kwa chikumbumtima).

Analogs ndiotsika mtengo kuposa Rosinsulin

Popeza Rosinsulin pakadali pano palibe amene angagulitsidwe, ndipo amangoperekedwa chifukwa cha mankhwala aulere, mufakisoni muyenera kusankha mayendedwe ake, makamaka, ndiotsika mtengo. Mwachitsanzo, "insulin yayifupi" ndi:

Mwa awa, Actrapid wachuma kwambiri.

Analogs a "medium" insulin Rosinsulin S ndi M osakaniza adzakhala:

Biosulin ndiye malo otsika mtengo kwambiri pano.

Ndemanga za Rosinsulin

Mankhwalawa ndi opanga mkati - chifukwa chake, amalowetsedwa mwachangu mu njira yosamalira matenda a shuga. Kuphatikiza, ndi mankhwalawa omwe tsopano, nthawi zambiri amakhala m'malo osagwiritsa ntchito njira zina, omwe amapatsidwa malangizo aulere m'zipatala. Inde, izi zimayambitsa nkhawa kwambiri kwa odwala komanso kuwunika kwawo kwa Rosinsulin kumawonetsa bwino izi:

- Adokotala anga adayamba kundiuza za Rosinsulin, ndikumtamanda. Koma ine ndinakana. Pakadali pano, tsiku lina adandiuza mwachindunji kuti tsopano ndi mankhwala okhawo omwe adzalembetsedwe. Ndipo akunja onse akhoza kugulidwa ndi ndalama zawo. Sanandisiyiretu chosankha. Tithokoze Mulungu, ndadutsa moyenera. Koma tsopano kulibe mtendere - ndikudikirira mavuto.

- Miyezi isanu ndi umodzi kale ku Rosinsulin (yotanthauziridwa ndi mphamvu). Shuga adayamba kulumpha. Ndikusintha mlingo, koma nthawi zina kumangokhala nkhawa.

Odwala ena adazolowera insulin imeneyi ndipo amachitamandanso:

- Ndazindikira kuti ambiri mwa mavuto amabwera chifukwa cha mantha komanso kusakhulupirirana. Pafupifupi pafupifupi chaka tsopano ndakhala ndikulowetsa Rosinsulin ndipo ndikuwona kuti amagwira ntchito bwino kwambiri.

- Nthawi yomweyo ndidayamba jakisoni ku Rosinsulin. Shuga amagwira momwe ayenera. Chifukwa chake musachite mantha.

Chifukwa chachikulu chosakhutira kwa odwala matenda ashuga ndikuti kwa iwo kugwiritsa ntchito insulin imodzi kapena ina ndiye chinsinsi chokhala ndi moyo wabwino. Kwa zaka, odwala akhala akusankha mankhwala osokoneza bongo, kusintha chithandizo, kusintha moyo wawo ... Panthawi imeneyi, kusinthana (ndipo nthawi zambiri mwalamulo) kupita ku mankhwala ena aliwonse kumatsimikizirika kukhala tsoka. Ngakhale chida ichi chitha kukhala chothandiza.

Chifukwa chachiwiri ndikusakhulupirira chidaliro cha inshuwaransi. Mankhwala omwe amapangidwa mdziko lathu m'mbuyomu anali operewera ndipo sakanatha kupikisana, komanso kuposa pamenepo, amabwezeretsa mankhwala ochokera kunja.

Zachidziwikire, ndibwino kuti wodwala aliyense azilandira insulini yake "- yoyenera bwino. Koma, tsoka, momwe zinthu ziliri pakali pano sizotheka. Komabe, chiyembekezo ndi malingaliro wamba zimayenera kupitilizidwa. Odwala ambiri asintha mankhwala awo kopitilira kamodzi - kudziwongolera payekha shuga komanso upangiri wa nthawi yake wazachipatala ndizofunikira pano. Ndipo zikuwoneka kuti Rosinsulin akuwonetsa kugwira ntchito kwake.

Re: Sinthani ku Rosinsulin kapena ayi?

QVikin "Aug 28, 2010 9:57 pm

Re: Sinthani ku Rosinsulin kapena ayi?

Chanterelle25 »Aug 29, 2010 10:44 am

Re: Sinthani ku Rosinsulin kapena ayi?

Irina "Aug 29, 2010 3:48 p.m.

Chanterelle 25 adalemba: Irina

Mukuganiza kuti ndikosavuta kupeza mwamuna wachuma ku Ivanovo?
Kapena ntchito yokhala ndi ndalama zokwanira za insulin ndi zingwe?

inde. sikuti kwenikweni ndi Hava!

Za kupeza insulin. Zimapezeka ndikulembetsa. Ndinakuwuzani kale za ku Ivanovo. Sindikudziwa wodwala wina wazaka zanga ali ndi ine yemwe angapatsidwe insulini mu mbale. Nthawi zambiri, zipatala zokha ndizomwe zimachita izi kwa agogo.

ndipo inde, ndikukumbukira zomwe ndidali nazo komwe ndidakubwerera ku mafunso a LS. Ndikuganiza, mwina ndiye kuti ndikhala ndikulembetsa ku Yves - sindikhala ndi vuto ndi kulembetsa pano.

Re: Sinthani ku Rosinsulin kapena ayi?

Irina "Aug 29, 2010 3:53 pm

QVikin analemba: Irina
Inu insulin panthawi yomwe mumapatsidwa imakhala kuti?
Ndimawapeza m'chigawo cha Sverdlovsk, chifukwa ndili ndi chilolezo chokhala kumeneko ..

Kodi ndiye izi zomwe mukulembako zachokera ku Sverdlovsk Region? Ndipo zaka zonse pamene amaphunzira, adayendetsa? Mukukhala kuti?

inde, mwina adadziyendetsa yekha kapena adadi - makolo anga aliko. ndipo ndikhala ndi moyo - pano - pano. ndichifukwa chake sindinalembetse pano - Ndinalemba kale (pamwambapa), koma ngati ndingathe kuzilandira bwino pamenepa, zikutanthauza kuti ndiyenera kulembetsa kuno, mwina. hmm, ndikudzifunsa ngati kungokhalapo zovuta ZAMBIRI kapena zochuluka za izo?

Re: Sinthani ku Rosinsulin kapena ayi?

Elechka "Aug 29, 2010 11:09 PM

Re: Sinthani ku Rosinsulin kapena ayi?

Irina "Aug 30, 2010 2:04 pm

Zikomo, El !!

mawu olimbikitsa ndi a kuti.

Re: Sinthani ku Rosinsulin kapena ayi?

Kumwetulira Juni 28, 2011 9:12 p.m.

Re: Sinthani ku Rosinsulin kapena ayi?

ECB Vladimir »Jun 29, 2011 1:52 pm

Re: Sinthani ku Rosinsulin kapena ayi?

Kumwetulira »Jun 29, 2011 7: 31 pm

Re: Sinthani ku Rosinsulin kapena ayi?

ECB Vladimir Juni 30, 2011 03:06 AM

Re: Sinthani ku Rosinsulin kapena ayi?

Kumwetulira Juni 30, 2011 07:44 AM

Re: Sinthani ku Rosinsulin kapena ayi?

ECB Vladimir Juni 30, 2011 10:36

Rosinsulin: ndemanga pakugwiritsa ntchito insulin, malangizo

Rosinsulin C imayendetsedwa mobwerezabwereza 1-2 pa tsiku, pafupifupi theka la ola musanadye. Nthawi iliyonse, tsamba la jakisoni liyenera kusinthidwa.

Nthawi zina, endocrinologist angafotokozere wodwalayo mu mnofu jakisoni wa mankhwala.

• ndi matenda a shuga 1
• mu gawo la kukana hypoglycemic mkamwa mankhwala,
• Mankhwala ophatikizidwa pamodzi (okana pang'ono ndi mankhwala amkamwa)
• ndi mono - kapena kuphatikiza chithandizo pamankhwala othandizira,
• ndi matenda wamba
• ndi shuga mwa amayi apakati, pamene chithandizo cha zakudya sichimapereka zotsatira zomwe mukufuna.

Mlingo ndi makonzedwe

Kuyimitsidwa kwa jekeseni wa subcutaneous. Contraindication ndi hypoglycemia, hypersensitivity.

Rosinsulin C imayendetsedwa mobwerezabwereza 1-2 pa tsiku, pafupifupi theka la ola musanadye. Nthawi iliyonse, tsamba la jakisoni liyenera kusinthidwa. Nthawi zina, endocrinologist angafotokozere wodwalayo mu mnofu jakisoni wa mankhwala.

Tcherani khutu! Mtsempha wa magazi insulin ya sing'anga nthawi yoletsedwa! Munthawi zonse, dokotala amasankha payekha mlingo, womwe umatengera mawonekedwe a matendawa komanso zomwe zili m'magazi ndi mkodzo.

Mlingo wamba ndi 8-24 IU, womwe umaperekedwa kamodzi pa tsiku, chifukwa mumatha kugwiritsa ntchito insulini ndi singano yochotsa.
Mwa ana ndi akulu omwe ali ndi chidwi chachikulu ndi mahomoni, mlingo umatha kuchepetsedwa mpaka 8 IU patsiku, ndipo, mosiyana, kwa odwala omwe ali ndi chidwi chochepa - kuchuluka kwa 24 IU patsiku kapena kupitirira.

Ngati mlingo wa tsiku ndi tsiku wa mankhwalowo uposa 0.6 IU / kg, umathandizidwa kawiri patsiku m'malo osiyanasiyana. Ngati mankhwalawa amaperekedwa mu 100 IU patsiku kapena kuposerapo, wodwalayo ayenera kuchipatala. Kusintha kwa insulin imodzi kupita kwina kuyenera kuchitika moyang'aniridwa ndi madokotala.

Pharmacokinetics

Mankhwalawa amatanthauza ma insulin apakatikati, omwe amalangizidwa:

1. Kuchepetsa magazi
2. Kuonjezera mayamwidwe a shuga ndi minofu,
3. Kupititsa patsogolo glycogenogeneis ndi lipogeneis,
4. Kuchepetsa kuchuluka kwa shuga m'magazi,
5. kaphatikizidwe kazakudya zama protein.

Zotsatira zoyipa

• angioedema,
• kupuma movutikira
• urticaria
• kutsika kwa magazi,
• malungo.

1. zolimbitsa thukuta,
2. khungu
3. njala
4. kugunda kwa mtima
5. nkhawa
6. thukuta
7. chisangalalo
8. kunjenjemera
9. paresthesia mkamwa,
10. kugona
11. kukhumudwa
12. machitidwe osazolowereka
13. kusakhazikika
14. kusatsimikizika kwa mayendedwe
15. mantha
16. malankhulidwe ndi mawonekedwe owoneka,
17. kusowa tulo
18. mutu.

Ndi jakisoni wosaiwalika, mlingo wotsika, motsutsana ndi matenda kapena kutentha thupi, ngati zakudya sizikutsatiridwa, matenda ashuga acidosis ndi hyperglycemia atha:

• kuchepa kwamtima
• ludzu
• kugona
• kukopa kwa nkhope,
• kuda nkhawa mpaka kugona.
• kuchepa kwakanthawi kowoneka koyambirira kwamankhwala.

Malangizo apadera

Musanatolere vutoli kuchokera ku vial, onetsetsani kuti yankho likuwonekera. Ngati matope kapena vuto lazindikirika pakukonzekera, ndiye kuti singathe kugwiritsidwa ntchito.

Kutentha kwa yankho la makonzedwe kuyenera kufanana ndi kutentha kwa chipinda.

Chofunikira! Ngati wodwala ali ndi matenda opatsirana, matenda a chithokomiro, hypopituitarism, matenda a Addison, kulephera kwaimpso, komanso kwa anthu azaka zopitilira 65, kusintha kwa insulin ndikofunikira.

Zomwe zimayambitsa hypoglycemia zitha kukhala:

1. M'malo mankhwalawa.
2. Bongo.
3. Kudumpha chakudya.
4. Matenda omwe amachepetsa kufunika kwa mankhwalawa.
5. Vomiting, kutsegula m'mimba.
6. Hypofunction wa adrenal kotekisi.
7. Kupsinjika kwakuthupi.
8. Sinthani dera la jakisoni.
9. Kuchita ndi mankhwala ena.

Posamutsa wodwala kuchokera ku insulin ya nyama kupita ku insulin yaumunthu, kuchepa kwa ndende yamagazi ndikotheka.

Kufotokozera za ntchito ya mankhwala a Rosinsulin P

Rosinsulin P amatanthauza mankhwala omwe ali ndi chifupifupi hypoglycemic. Kuphatikiza ndi cholandirira cha membrane wakunja, yankho limapanga zovuta za insulin. Izi:

• kumawonjezera kaphatikizidwe ka cyclic adenosine monophosphate mu chiwindi ndi maselo amafuta,
• imapangitsa njira zamkati mwazochitika (pyruvate kinases, hexokinases, glycogen synthases ndi ena).

Kutsika kwa ndende yamagazi kumachitika chifukwa cha:

1. onjezera zoyendera zapamtunda,
2. kukondoweza kwa glycogenogeneis, lipogeneis,
3. mapuloteni kaphatikizidwe
4. kukonza mayamwidwe mankhwala ndi minofu,
5. kuchepa kwa kuwonongeka kwa glycogen (chifukwa cha kuchepa kwa kupanga kwa chiwindi ndi chiwindi).

Pambuyo subcutaneous makonzedwe, mphamvu ya mankhwalawa amapezeka 20-30 mphindi. The kuchuluka ndende mu magazi zimatheka pambuyo maola 1-3, ndi kupitiriza kwa zochita zimadalira malo ndi njira kasamalidwe, mlingo ndi munthu payekha wodwala.