Kodi hyperinsulinemia ndi chiyani ndipo ndi chifukwa chiyani? Kodi hyperinsulinism ndi chiyani?

Nthawi zambiri anthu amakhala ndi vuto lolemera, motero amadzichiritsa okha ndi zakudya zopweteka kwambiri komanso kuchita masewera olimbitsa thupi mopitirira muyeso, koma sangathe kuchepetsa thupi.

Poterepa, ndikofunikira kufufuza zomwe zimayambitsa mkati mwa thupi.

Chimodzi mwa izo ndi hyperinsulinemia.

Makalata ochokera kwa Owerenga

Agogo anga akhala akudwala matenda a shuga kwa nthawi yayitali (mtundu 2), koma posachedwapa mavuto atuluka pamiyendo ndi ziwalo zamkati.

Mwangozi ndidapeza nkhani pa intaneti yomwe idapulumutsa moyo wanga. Ndidalumikizidwa kumeneko kwaulere pafoni ndipo ndidayankha mafunso onse, ndikuuzidwa momwe ndingachitire ndi matenda ashuga.

Patatha milungu iwiri atatha kulandira chithandizo, agogo aja adasinthiratu momwe akumvera. Ananenanso kuti miyendo yake sikupweteka komanso zilonda zake sizinayende; sabata yamawa tidzapita ku ofesi ya dotolo. Falitsa ulalo wa nkhaniyo

Matenda a Pancreatic

Zimachitika kuti amapanga insulin yambiri.

Pancreatic hyperfunction imayambitsidwa ndi matenda ake: kutupa, kupezeka kwa cysts, zotupa zopweteka, mwachitsanzo, matenda a hepatitis kapena parasitic.

Amayambitsa kusokonezeka kwa dongosolo la ziwonetsero lazida

Chimodzi mwazinthu zamagulu amanjenje ndizoyang'anira ziwalo zamkati, kuphatikizapo kapamba. Pogwira ntchito mopitirira muyeso ya nthambi yachifundo ya autonomic mantha dongosolo, gululi limayamba kugwira ntchito mopitirira muyeso.

Chosangalatsa ndichakuti, mayesowo samawulula momwe adaliri. Poterepa, ntchito yokhayo yomwe ili ndi vuto.

Zomwezi zimachitikanso ndi hyperinsulinemia. Cancreas ndiyabwino, komabe, kukondoweza kwambiri kwa mtima wake wamafundo kumabweretsa ntchito yowonjezereka, chifukwa chake, kumachulukitsa kwa insulin.

Kuzindikira kwa shuga - ingomwani tsiku lililonse.

Hyperinsulinism

Hyperinsulinism (matenda a hypoglycemic) ndi chinthu chobadwa nacho kapena chokhala ndi matenda amkati mwa hyperinsulinemia. Zizindikiro za matendawa adayamba kufotokozedwa koyambirira kwa zaka za zana la makumi awiri ndi dotolo waku America a Harris ndi dokotala wa opaleshoni yapakhomo Oppel. Congenital hyperinsulinism ndi chosowa kwambiri - 1 kesi pa 50,000 yatsopano. Matendawa amapezeka ndi zaka zambiri ndipo amakhudza azimayi. Matenda a Hypoglycemic amapezeka ndi nthawi yosakhalapo kwa zizindikiro zazikulu (kuchotsedwa) komanso nthawi yayitali yopanga chithunzi (kuukira kwa hypoglycemia).

Zoyambitsa Hyperinsulinism

Matenda agengenital amapezeka chifukwa cha kutukuka kwa intrauterine, kufalikira kwa fetal, kusintha kwa matupi athu. Zomwe zimayambitsa matenda a hypoglycemic omwe amagawidwa pancreatic, zimayambitsa kukulitsa kwa hyperinsulinemia, komanso yopanda pancreatic, ndikuwonjezera kuchuluka kwa insulin. Pancreatic mawonekedwe a matendawa amapezeka ndi zilonda zapakhosi kapena benign neoplasms, komanso pancreatic beta cell hyperplasia. Fomu yopanda pancreatic imayamba mu zotsatirazi:

• Kuphwanya zakudya. Kutopa kwa nthawi yayitali, kuchepa kwamadzi ndi glucose (kutsekula m'mimba, kusanza, kuyamwa), kuchita masewera olimbitsa thupi popanda kudya zakudya zamagulu am'thupi kumapangitsa kuchepa kwambiri kwa shuga m'magazi. Kugwiritsa ntchito zakudya zamafuta ochulukitsa kumawonjezera shuga m'magazi, zomwe zimapangitsa kuti insulin ipange.
• Kuwonongeka kwa chiwindi cha ma etiologies osiyanasiyana (khansa, mafuta a hepatosis, cirrhosis) kumayambitsa kuchepa kwa milingo ya glycogen, kusokonezeka kwa metabolic ndi hypoglycemia.
• Kudya kosaloledwa kwa mankhwala ochepetsa shuga a shuga mellitus (ma insulin, omwe amachokera ku insulin, sulfonylureas) amachititsa mankhwala osokoneza bongo a hypoglycemia.
• Matenda a Endocrine omwe amatsogolera kuchepa kwa kuchuluka kwa mahomoni a contrainsulin (ACTH, cortisol): pituitary dwarfism, myxedema, matenda a Addison.
• Kuperewera kwa ma enzymes okhudzana ndi glucose metabolism (hepatic phosphorylase, aimpso insulinase, glucose-6-phosphatase) kumayambitsa wachibale hyperinsulinism.

Glucose ndiye gawo lalikulu la michere chapakati ndipo ndizofunikira kuti ubongo uzigwira bwino ntchito. Miyezi yambiri ya insulin, kudzikundikira kwa glycogen m'chiwindi ndi kulepheretsa kwa glycogenolysis kumabweretsa kuchepa kwa shuga wamagazi. Hypoglycemia imayambitsa zopinga za metabolic ndi mphamvu zama cell mu ubongo. Kukondoweza kwa dongosolo la sympathoadrenal kumachitika, kupanga catecholamines kumawonjezeka, kuukira kwa hyperinsulinism kumayamba (tachycardia, irritability, a mantha). Kuphwanya njira za redox mu thupi kumayambitsa kuchepa kwa kugwiritsa ntchito kwa okosijeni ndi maselo a chithokomiro cha m'magazi komanso kukula kwa hypoxia (kugona, kunenepa, kusayang'anira). Kuperewera kwa shuga kumapangitsa kuphwanya njira zonse za metabolic mthupi, kuchuluka kwa magazi kupita ku ziwongo za ubongo ndi kuphipha kwa zotumphukira za m'mitsempha, zomwe zingayambitse matenda amtima. Pamene zida zakale zaubongo zimakhudzidwa ndi njira ya pathological (medulla oblongata ndi midbrain, Varolius Bridge) malo olimbikitsa, diplopia, komanso kusokonezeka kwa kupuma ndi mtima kumakula.

Gulu

Mu chipatala endocrinology, gulu lomwe limagwiritsidwa ntchito kwambiri m'magulu a hyperinsulinemia kutengera zomwe zimayambitsa matendawa:

1. Hyperinsulinism yoyamba (pancreatic, organic, mtheradi) ndizotsatira za chotupa kapena ma hyperplasia a maselo a beta a islet pancreatic zida. Kuwonjezeka kwamankhwala a insulin 90% kumathandizidwa ndi benign neoplasms (insulinoma), ocheperako, olakwika neoplasms (carcinoma). Organic hyperinsulinemia imachitika kwambiri mawonekedwe ndi otchulidwa matenda chithunzi ndi pafupipafupi matenda a hypoglycemia. Kugwa kwakuthwa kwa shuga m'magazi kumachitika m'mawa, chifukwa chodumphira chakudya. Kwa matenda amtunduwu, Whipple triad ndi mawonekedwe: Zizindikiro za hypoglycemia, kuchepa kwambiri kwa shuga m'magazi ndikusiya kuukira poyambitsa shuga.
2. Second hyperinsulinism (yogwira ntchito, wachibale, extrapancreatic) imalumikizidwa ndi kuchepa kwamahomoni olimbana ndi mahomoni, kuwonongeka kwa dongosolo lamanjenje ndi chiwindi. Kuukira kwa hypoglycemia kumachitika pazifukwa zakunja: kufa ndi njala, mankhwala osokoneza bongo a hypoglycemic, kuchita zolimbitsa thupi kwambiri, kugwedezeka kwam'maganizo. Kuchulukitsa kwa matendawa kumachitika mosakhazikika, pafupifupi kosakhudzana ndi chakudya. Kusala kudya kwatsiku ndi tsiku sikubweretsa zidziwitso zambiri.

Zizindikiro za Hyperinsulinism

Chithunzi chachipatala cha matenda a hypoglycemic ndi chifukwa cha kuchepa kwa shuga wamagazi. Kukula kwa kuukira kumayambira ndikuwonjezeranso chidwi cha kudya, thukuta, kufooka, tachycardia ndikumverera kwa njala. Pambuyo pake mantha akujowina: mantha, nkhawa, kusakwiya, kunjenjemera miyendo. Ndi chitukuko chopitilira kuukira, kusokonezeka m'malo, diplopia, paresthesia (dzanzi, kumva kukuwa) m'malire, mpaka kugwa, akuti. Ngati sanalandiridwe, amachoka pomwepo. Nthawi yopatsirana imawonetsedwa ndi kuchepa kwa kukumbukira, kusokonezeka kwa malingaliro, chidwi, kusokonezeka kwa chidwi ndi dzanzi m'ziwalo. Kudya pafupipafupi komwe kumakhala ndi michere yambiri yamagetsi kumapangitsa kuti thupi lizikula komanso kuti kunenepa kwambiri.

Muzochita zamakono, pali madigiri atatu a hyperinsulinism, kutengera kuwuma kwa matendawa: ofatsa, odziletsa komanso okhwima. A digiri yofatsa imawonetsedwa ndi kusapezeka kwa zizindikiro za nthawi yopatsirana komanso zotupa za chithokomiro cha ubongo. Kuchulukitsa kwa matendawa kumachitika osakwana nthawi 1 pamwezi ndipo kumayimitsidwa mwachangu ndi mankhwala kapena zakudya za shuga. Ndi zovuta zolimbitsa thupi, kukomoka kumachitika nthawi yopitilira 1 pamwezi, kusowa kwa chikumbumtima komanso kukula kwa chikumbumtima ndikotheka. Nthawi yopatsirana imadziwika ndi zovuta zofatsa (kuiwala, kuchepa kwa malingaliro). Mulingo wambiri umayamba ndi kusintha kosasintha mu ubongo. Pankhaniyi, kukomoka kumachitika nthawi zambiri ndikutha ndikutaya chikumbumtima. Munthawi yopatsirana, wodwalayo amasokonezeka, kukumbukira kumachepa kwambiri, kugwedezeka kwamphamvu kumadziwika, kusintha kwakuthwa m'maganizo ndikuwonjezereka kwa mkwiyo.

Mavuto a Hyperinsulinism

Mavuto amatha kugawidwa kumayambiriro komanso mochedwa. Mavuto oyambilira omwe amachitika patangotha ​​maola ochepa pambuyo poti aukira aphatikize stroke, myocardial infarction chifukwa kuchepa kwambiri kwa kagayidwe kazigawo ka minofu ya mtima ndi ubongo. Pakakhala zovuta, chikomokere cha hypoglycemic chimakula. Pambuyo pake zovuta zimawonekera miyezi yambiri kapena zaka pambuyo poyambitsidwa kwa matendawa ndipo amadziwika ndi vuto la kukumbukira komanso kuyankhula, parkinsonism, encephalopathy. Kuperewera kwa njira yodziwira matendawa ndikuthandizira matendawa kumabweretsa kufooka kwa ntchito ya endocrine ya kapamba ndi kukula kwa matenda a shuga, matenda a metabolic, komanso kunenepa kwambiri. Congenital hyperinsulinism mu 30% ya milandu imabweretsa matenda osokoneza bongo a ubongo komanso kuchepa kwa kukula kwamaganizidwe kwa mwana.

Kuzindikira Hyperinsulinism

Kuzindikira kumakhazikitsidwa pa chithunzi cha chipatala (kusowa kwa chikumbumtima, kugwedezeka, psychomotor mukubwadamuka), zambiri pazolemba zamankhwala (nthawi yoyambitsa kuukira, ubale wake ndi kudya). The endocrinologist amafotokoza kukhalapo kwa matenda aconfitant komanso matenda obadwa nawo (mafuta a hepatosis, matenda a shuga, matenda a Itsenko-Cushing's, pambuyo pake amapanga maphunziro a labotale komanso othandizira. Wodwalayo amakhala ndi glucose wa tsiku ndi tsiku (mbiri ya glycemic). Pamene zopatuka zikapezeka, kuyesedwa koyenera kumachitika. Chiyeso chofulumira chimagwiritsidwa ntchito pozindikira kusiyanitsa kwa pulayimale komanso sekondale. Pa kuyesedwa, C-peptide, immunoreactive insulin (IRI) ndi glucose wamagazi amayeza. Kuwonjezeka kwa zizindikirozi kukuwonetsa mtundu wa matendawa.

Kutsimikizira pancreatic etiology ya matendawa, kuyesedwa kumachitika kuti timvetsetse tolbutamide ndi leucine. Ndi zotsatira zabwino za mayeso ogwira ntchito, ultrasound, scintigraphy ndi MRI ya zikondamoyo akuwonetsedwa. Ndi yachiwiri hyperinsulinism, kupatula ma neoplasms a ziwalo zina, ma ultrasound am'mimba, ubongo MRI imachitidwa. Kusiyanitsa kosiyanasiyana kwa matenda a hypoglycemic kumachitika ndi Zollinger-Ellison syndrome, kuyambika kwa mtundu wa 2 matenda a shuga, matenda amitsempha, zotupa za mu ubongo ndi matenda amisala.

Hyperinsulinism Chithandizo

Njira zamankhwala zimatengera zomwe zimayambitsa hyperinsulinemia. Ndi organic genesis, opaleshoni ya opaleshoni ikuwonetsedwa: kusinthanitsa pang'ono kwa kapamba kapena kapamba konse, kukokomeza kwa neoplasm. Kuchuluka kwa maopareshoni kumatsimikiziridwa ndi malo ndi kukula kwa chotupa. Pambuyo pakuchita opaleshoni, kuchepa kwa mphamvu kwa hyperglycemia nthawi zambiri kumadziwika, kumafuna kuwongolera kuchipatala komanso kudya kokhala ndi zakudya zochepa. Matenda a mtundu wa zizindikiro amapezeka mwezi umodzi atatha kulowererapo. Ndi zotupa zosagwiritsidwa ntchito, mankhwala a palliative amachitika pofuna kupewa hypoglycemia. Mu neoplasms yoyipa, chemotherapy imasonyezedwanso.

Ntchito hyperinsulinism kwenikweni imafunikira chithandizo cha matenda omwe amayambitsa kuchuluka kwa insulin. Odwala onse amapatsidwa zakudya zoyenera komanso kuchepa kwamphamvu kwa chakudya chamagulu (gr. Patsiku lililonse). Zokonda zimaperekedwa ku zovuta zamatumbo (mkate wa rye, supu ya tirigu wa durum, phala lonse la tirigu, mtedza). Chakudya chizikhala chopindika, nthawi 5-6 patsiku. Chifukwa chakuti kuwukira kwakanthawi kumayambitsa kukhazikitsidwa kwa mantha pakati pa odwala, kufunsira kwa katswiri wamalingaliro kumalimbikitsidwa. Ndi kukula kwa vuto la hypoglycemic, kugwiritsa ntchito chakudya cham'mimba chotsekemera (tiyi wokoma, maswiti, mkate Woyera) akuwonetsedwa. Popeza simukudziwa, kupangika kwa shuga 40% ndikofunikira. Ndi kupweteka komanso kugwedezeka kwambiri kwa psychomotor, jakisoni wa bata ndi kusinkhidwa akuwonetsedwa. Chithandizo cha matenda oopsa a hyperinsulinism ndi chitukuko cha chikomokerezi chimachitika m'chipinda chosamalitsa cha anthu odwala komanso kulowetsedwa kwa detoxation, kuyambitsa glucocorticoids ndi adrenaline.

Zotsogola ndi kupewa

Kupewera kwa matenda a hypoglycemic kumaphatikiza kudya mokwanira komanso kupatula kwa maola awiri ndi atatu, kumwa madzi okwanira, kusiya zizolowezi zoyipa, ndikuwongolera kuchuluka kwa shuga. Kusamalira ndi kukonza kagayidwe kachakudya mthupi, zolimbitsa thupi zolimbitsa thupi zimalimbikitsidwa potsatira zakudya. Kukula kwa hyperinsulinism kumatengera gawo la matendawa komanso zomwe zimapangitsa insulinemia. Kuchotsa kwa benign neoplasms mu 90% ya milandu kumapereka kuchira. Zotupa zosagwira ndi zopweteka zimayambitsa kusintha kwamitsempha ndipo zimafunikira kuwunika wodwalayo nthawi zonse. Chithandizo cha matenda oyambitsidwa ndi mawonekedwe amachitidwe a hyperinsulinemia kumabweretsa kubwezeretsanso kwa zizindikiro ndi kuchira kwamtsogolo.

Hyperinsulinemia - zizindikiro zazikulu:

• Zofooka
• Zopweteka
• Chizungulire
• Pakamwa pakamwa
• Khungu lowuma
• Kugona
• Kupweteka kwa minofu
• Chisoni
• Ludzu lalikulu
• Mawonedwe otsika
• Kunenepa kwambiri
• Lethargy
• Maonekedwe a totambalala matanda
• Kusokonezeka kwa m'mimba
• Khungu limachita khungu

Hyperinsulinemia ndi matenda opatsirana omwe amadziwika ndi kuchuluka kwa insulin komanso shuga yochepa ya magazi. Njira yothandizirana ndi zoterezi imatha kubweretsa osati chododometsa pakugwira ntchito kwina kwa machitidwe ena a mthupi, komanso chiwopsezo cha hypoglycemic, chomwe chokha chomwe chili pachiwopsezo cha moyo wa munthu.

Matenda obadwa nawo a hyperinsulinemia ndi osowa kwambiri, pomwe owapeza amapezeka, nthawi zambiri, ali ndi zaka. Amadziwikanso kuti azimayi amakonda kutenga matenda otere.

Chithunzi chachipatala cha matenda azachipatalachi sichimakhala chachindunji, chifukwa chake, ngati atapezeka mozindikira, dokotala amatha kugwiritsa ntchito njira za kafukufuku komanso zogwiritsira ntchito. Nthawi zina, matenda osiyanasiyana amafunikira.

Chithandizo cha hyperinsulinimism chimachokera ku mankhwala, kudya komanso kuchita masewera olimbitsa thupi. Ndi zoletsedwa kuchitira zochiritsa mwakufuna kwanu.

Hyperinsulinemia imatha kukhala chifukwa cha zotsatirazi zotsatsa:

• kuchepa kwa chidwi cha insulin receptors kapena kuchuluka kwawo,
• kupanga kwambiri kwa insulin chifukwa cha njira zina za thupi.
• kusintha kwa shuga m'magazi,
• Kulephera posayina mu foni.

Zomwe zimapangitsa kukonzekera kwa njira yotereyi ndi izi:

• kubadwa kwamtundu wamatenda amtunduwu,
• kunenepa
• kumwa mankhwala a mahomoni ndi mankhwala ena "olemetsa",
• ochepa matenda oopsa
• kusintha kwa thupi
• pamaso pa polycystic ovary syndrome,
• ukalamba
• kupezeka kwa zizolowezi zoipa monga kusuta fodya komanso uchidakwa.
• zolimbitsa thupi
• mbiri ya atherosulinosis,
• kuperewera kwa zakudya m'thupi.

Nthawi zina, zomwe ndizosowa kwambiri, zomwe zimayambitsa hyperinsulinemia sizitha kukhazikitsidwa.

Zizindikiro

Pa magawo oyambirira a chitukuko, zizindikiro za njirayi zimatsala pang'ono kuzimiririka, zomwe zimayambitsa kuzengereza kuzindikirika komanso kulandira chithandizo mosayembekezereka.

Pamene matenda azachipatala akuchulukirachulukira, zizindikiro zotsatirazi zingakhalepo:

• ludzu losalekeza, koma limawuma mkamwa.
• kunenepa kwam'mimba, ndiko kuti, mafuta amadzaza pamimba ndi m'chiuno,
• chizungulire
• kupweteka kwa minofu
• kufooka, ulesi, ulesi,
• kugona
• khungu ndi kuuma kwa khungu,
• zovuta zam'mimba
• kuwonongeka kwamawonekedwe
• kupweteka kwa molumikizana
• Mapangidwe otambasuka chizindikiro pamimba ndi miyendo.

Chifukwa chakuti zizindikiro za matendawa ndi zopanda pake, muyenera kulumikizana ndi dokotala / dokotala kuti mupeze chithandizo choyambirira posachedwa.

Kupewa

Monga prophylaxis, munthu ayenera kutsatira malangizo onse okhudza moyo wathanzi, makamaka zakudya zopatsa thanzi.

Ngati mukuganiza kuti muli ndi Hyperinsulinemia ndi zomwe zikuwoneka ndi matendawa, madotolo akhoza kukuthandizani: endocrinologist, psychapist, ndi Dokotala wa ana.

Tiperekanso kugwiritsa ntchito ntchito yathu yofufuzira matenda omwe ali pa intaneti, yomwe imasankha matenda omwe angakhalepo kutengera ndi zomwe zalowetsedwa.

Matenda otopa kwambiri (abbr. CFS) ndi mkhalidwe womwe kufooka kwamthupi ndi kwakuthupi kumachitika chifukwa cha zinthu zosadziwika ndipo kumatha kuyambira miyezi isanu ndi umodzi kapena kupitirira apo. Matenda otopa kwambiri, zomwe zimayesedwa kuti zimagwirizanitsidwa kwakanthawi ndi matenda opatsirana, zimagwirizana kwambiri ndi kuthamanga kwa moyo wa anthu komanso kuchuluka kwachidziwitso komwe kumamuvutitsa munthu pakuzindikira.

Catarrhal tonillitis (pachimake tonsillopharyngitis) ndi njira ya m'magazi yomwe imayambitsidwa ndi microflora ya pathogenic, komanso kukhudza zigawo zapamwamba za mucosa wam'mero. Mtunduwu, malinga ndi terminology yamankhwala, umatchedwanso erythematous. Mwa mitundu yonse ya angina, iyi imawonedwa ngati yosavuta, koma izi sizitanthauza kuti sizikufunika kuthandizidwa. Momwe mungathandizire zilonda zam'mimba za m'mimba zitha kuuzidwa dokotala moyenera atatha kudziwa bwino matenda. Ndizofunikanso kudziwa kuti mankhwala osokoneza bongo sikuti nthawi zonse amafunikira kuthandizira matenda.

Hypervitaminosis ndi matenda omwe amachititsa kuchuluka kwa ichi kapena kuti mavitaminiwo alowe mthupi. Posachedwa, matenda oterewa afala kwambiri, popeza kugwiritsa ntchito mankhwala othandizira a Vitamini kukufalikira.

Matenda a shuga m'magulu a amuna ndi matenda a endocrine system, kumbuyo komwe kumakhala kuphwanya kusintha kwa madzi ndi michere m'thupi la munthu. Izi zimabweretsa kukanika kwa pancreatic, yomwe imayang'anira kupanga mahomoni ofunikira - insulin, chifukwa chomwe shuga sichisintha kukhala shuga ndikupanga magazi.

Matenda omwe amadziwika ndi kuwonongeka kwa minofu ndikuwonetsa kuwonongeka kwa magalimoto ndi mapangidwe a edema ndi erythema pakhungu amatchedwa matenda a Wagner kapena dermatomyositis. Ngati khungu limakhala kuti kulibe, ndiye kuti matendawa amatchedwa polymyositis.

Pogwiritsa ntchito masewera olimbitsa thupi komanso kudziletsa, anthu ambiri amatha kuchita popanda mankhwala.

Zizindikiro komanso chithandizo cha matenda amunthu

Kutenganso zinthu kumatha kokha pokhapokha ngati chilolezo cha oyang'anira chikugwirizana ndi kulumikizana komwe kukuchokera.

Zonse zomwe zaperekedwa zimayang'aniridwa ndi dokotala wanu!

Mafunso ndi malingaliro:

Zomwe zimachitika

Kutuluka kwa hyperinsulinism kumawonetsa kugwira ntchito kwa thupi. Zomwe zimayambira zimatha kulowa mkati mwazaka zambiri osadzipangitsa kumva. Matendawa amatchuka kwambiri mwa azimayi, amakhudzana ndi kusintha kwama mahomoni ambiri. Zoyambitsa zazikulu:

• Kupanga kwa insulin yosasinthika ndi kapamba, yemwe amasiyana pakapangidwe ndipo thupi silimadziwika.
• Kugwedezeka. Receptors sazindikira insulin, zomwe zimabweretsa kupanga osalamulirika.
• Kusokoneza kwa shuga m'magazi.
• Mitundu ya chibadwa.
• Kunenepa kwambiri
• Atherosulinosis
• Neurogenic anorexia ndimavuto amisala kutsutsana ndi maziko a lingaliro loonera mopitirira muyeso, lomwe limaphatikizapo kukana kudya, ndipo pambuyo pake zovuta za endocrine, kuchepa magazi, komanso kusinthasintha kwa shuga m'magazi.
• Oncology pamimba.

Bwererani ku tebulo la zomwe zili

Magulu owopsa

Kukhazikika kwawonjezeranso insulin ndi chitukuko cha hyperinsulinism kumachitika:

Amayi omwe amakhala ndi ovary ya polycystic amatha kukhala ndi vutoli.

• Mwa anthu okhala ndi chikhalidwe chobadwa nacho. Ngati pakati pa achibale pali omwe apezeka ndi matendawa, ndiye kuti chiwopsezocho chimawonjezeka kangapo. Asayansi atsimikizira kuti kupezeka kwa ma antigen a HLA kumabweretsa kuwonekera kwa hyperinsulinism.
• Panthawi ya mantha oyenda mkati mwa dongosolo lamkati, ubongo umapereka cholakwika, chomwe chimapangitsa kuti insulini ichuluke.
• Wamkazi madzulo osanachitike.
• Mukamachita zinthu zotsika kwambiri.
• Mukalamba.
• Odwala omwe ali ndi polycystic appendages.
• Anthu omwe amatenga mahomoni amakhala ndi ma beta-blockers.

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Kodi matenda oopsa otani?

Matenda aliwonse pakalibe chithandizo choyenera amabweretsa zovuta. Hyperinsulinism imangokhala yovuta kwambiri, komanso yodwala, yomwe nthawi zambiri imakhala yovuta kwambiri kukana. Matenda osachiritsika amalepheretsa ubongo kugwira ntchito ndipo imakhudza chikhalidwe cha wodwalayo, ndipo mwa abambo, potency imakulirakulira, yomwe imadzala ndi kusabereka. Congenital hyperinsulinism mu 30% yamilandu imatsogolera ku vuto la okosijeni la ubongo ndipo imakhudza kukula kwathunthu kwa mwana. Pali mndandanda wazinthu zina zomwe muyenera kulabadira:

• Matendawa amakhudza kugwira ntchito kwa ziwalo zonse ndi machitidwe.
• Hyperinsulinism ingayambitse matenda ashuga.
• Pali kulemera kosalekeza ndimotsatira zotsatirazi.
• Chiwopsezo cha kukomoka kwa hypoglycemic chikukwera.
• Mavuto ndi mtima wamagetsi amakula.

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Kuzindikira matendawa

Kuzindikiritsa kwa hyperinsulinism kumakhala kovuta chifukwa cha kusowa kwa chizindikiro, ndipo nthawi zambiri ndi asymptomatic. Ngati vuto lonselo likuipiraipira, muyenera kufunsa dokotala. Chiyeso chotseguka cha mahomoni okhala ndi chithunzi chathunthu cha kapamba ndi pituitary gland chidzafunika. Pakukayikira, MRI ya pituitary gland imachitika ndi chikhomo, chomwe chimathetsa mwayi wa oncology. Kwa azimayi, kuzindikira kwake kumakhazikitsidwa ndi ultrasound yam'mimba, ziwalo zoberekera, popeza nthendayi imalumikizidwa ndikupanga mahomoni. Kuti muwonetsetse zotsatirazi, muyenera kuyeza kuthamanga kwa magazi ndikuwona kuchuluka kwa shuga m'magazi. Madandaulo a wodwala amatengedwa, omwe angatsimikizire kupezeka kwa matendawa.

Kuchiza matenda

Ngati hyperinsulinism yapezeka koyambirira, pali mwayi waukulu wochiritsa matendawa. Chakudya chopatsa thanzi chimakhala ndi gawo lalikulu, chakudya chimatsatiridwa, kutsatira mosamala ndandanda yake. Kuchita masewera olimbitsa thupi kumawonjezeka, komwe kumakupatsani mwayi wokuthandizira kagayidwe kachakudya, tichotsereni kunenepa kwambiri. Mimba imathandizira chithandizo, ndipo zakudya zimasiyana. Dotolo adzaphatikizanso vitamini yovuta yomwe imalola kuti thupi lizikula bwino. Ngati ndi kotheka, onjezerani:

• mankhwala oletsa kuchepetsa magazi,
• metabolic mankhwala
• chilakolako chopondera.

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Zakudya za hyperinsulinism

Kukhala ndi moyo wathanzi kumathandiza kupewa matenda ambiri, makamaka hyperinsulinism. Kupewa kumaphatikizapo:

• chakudya chopatsa thanzi, chopanda zowonjezera, utoto ndi mowa,
• kuwunikira nthawi zonse zaumoyo,
• kunenepa
• masewera a tsiku ndi tsiku
• amayenda mumlengalenga.

Ngati pali chizolowezi choyambika kwa matenda ashuga kapena mavuto ena okhudzana ndi njira ya metabolic m'thupi, ndikosavuta kusintha njira ya moyo kuposa kuchitira zotsatira pambuyo pake. Ndikofunika kukumbukira kuti matenda ngati awa samadutsa popanda kufufuza ndipo nthawi zonse amasiya kuyamwa, mwa odwala ena amakhalanso moyo wonse. Potere, chithandizo cha mankhwala osokoneza bongo komanso zoletsa zovuta pazakudya zimaphatikizidwa.

Chidziwitsocho chimaperekedwa kuti chizidziwitso chokha chokha ndipo sichingagwiritsidwe ntchito pakudzipanga nokha. Osadzinyengerera, zitha kukhala zowopsa. Nthawi zonse funsani dokotala. Pofuna kukopera mwatsatanetsatane kapena mwatsatanetsatane zinthu zomwe zili pamalowo, kulumikizana kwofunikira kukufunika.

Kukwera kwathunthu kwamankhwala a insulin, kapena hyperinsulinism: Zizindikiro, kuzindikira ndi chithandizo

Hyperinsulinism ndi matenda omwe amapezeka mwa mtundu wa hypoglycemia, omwe ndiwowonjezera pazachilendo kapena kuwonjezeka kwathunthu kwa insulin m'magazi.

Kuchuluka kwa timadzi timeneti kumapangitsa kuchuluka kwa shuga, komwe kumapangitsa kuti shuga achepetse, komanso kumayambitsa kuperewera kwa mpweya waubongo, komwe kumayambitsa vuto la manjenje.

Zochitika ndi zizindikiro

Matendawa amafala kwambiri mwa akazi ndipo amapezeka azaka za 26 mpaka 55. Kuukira kwa hypoglycemia, monga lamulo, kumawonekera m'mawa pambuyo pothamanga mokwanira. Matendawa amatha kuthandizika ndikuwonekera nthawi yomweyo patsiku, mutatha kumwa chakudya.

Hyperinsulinism imatha kupangitsa kuti anthu azikhala ndi njala nthawi yayitali. Zina zofunika pakuwonetsa matendawa zimatha kukhala zochitika zosiyanasiyana zolimbitsa thupi komanso zokumana nazo m'maganizo. Mwa akazi, zizindikiro zobwereza za matendawa zimachitika pokhapokha ngati nthawi yotsala isanakwane.

Zizindikiro za Hyperinsulinism zili ndi izi:

• njala yosatha
• kutuluka thukuta kwambiri
• kufooka wamba
• tachycardia
• womvera
• paresthesia
• diplopia
• kumakhala ndi mantha osaneneka
• kusokonezeka kwa malingaliro
• kugwedezeka kwa manja ndi miyendo yake,
• zochita zosakhudzidwa
• dysarthria.

Komabe, zizindikirazi ndi zoyambira, ndipo ngati simungazichiritse ndikupitiliza kunyalanyaza matendawa, zotsatira zake zimakhala zokulirapo.

Mtheradi hyperinsulinism imawonetsedwa ndi zizindikiro zotsatirazi:

• kulephera kwadzidzidzi
• coma ndi hypothermia,
• coma ndi hyporeflexia,
• tonic kukokana
• kukokana kwamankhwala.

Kukodwa koteroko kumachitika kaŵirikaŵiri pambuyo poti mwadzidzidzi mwadzidzidzi.

Asanayambe kuukira, zizindikiro zotsatirazi zimawonekera:

• utachepetsa kukumbukira
• kusakhazikika mtima
• kunyalanyaza kwathunthu ena
• kutayika kwa maluso aukadaulo,
• paresthesia
• Zizindikiro za kuperewera kwa piramidi,
• zamatsenga.

Mwachidule za matendawa

Mkhalidwe womwe ulipo, womwe nthawi zina umatchedwa hyperinsulism, ukhoza kukhala woyamba komanso wachiwiri. Yoyamba mwa mitundu yomwe yaperekedwa ya matenda amatchedwanso pancreatic mkhalidwe. Ichi ndichifukwa amapangika chifukwa cha zina za pathological zomwe zimakhudzana ndi kapamba. Polankhula za hyperinsinulism yachiwiri, ndikofunikira kumvetsetsa kuti matenda osiyanasiyana amatha kukhala owonjezera. Ichi ndichifukwa chake mawonekedwe amtunduwu amatchedwa kuti extrapancreatic.

Akatswiri amati chidwi chakuti matendawa sangakhudze malo okhawo omwe timapezekanso chifukwa cha kapamba, komanso amakhalanso okhazikika. Pankhaniyi, zosintha zazikulu zimadziwika mu gawo lililonse la minofu ya tinyezi. Kuti mumvetsetse bwino momwe mankhwalawa amayenera kuchitikira, ndikulimbikitsidwa kwambiri kuti mudziwe zomwe zimapangitsa kuti mukhale ndi hyperinsulinism.

Zifukwa zachitukuko

Matenda omwe aperekedwa, monga hyperinsulinemia, amatha kudziwika ndi mndandanda wambiri wowonjezera. Choyamba, zotupa mu zilumba za Langerhans, zomwe zimakhala zamtundu wankhanza komanso zoyipa, zimaganiziridwa. Choyambitsa china chimakhala matenda omwe amalumikizana ndi dongosolo lamkati lamanjenje - chapakati mantha dongosolo.

Kupitilira apo, akatswiri akuwonetsetsa kuti chithandizo chofunikira chimafunikira matendawa atakula chifukwa cha chotupa kapena kupweteka kwa kapamba.

Tisaiwale za zoopsa zomwe zingachitike chifukwa cha kuchuluka kwambiri kwa thupi, gawo loyamba la matenda ashuga. Zina, zosafunikira kwambiri ziyenera kuphatikizapo:

• kuwonongeka komwe kumayenderana ndi ziwalo za endocrine system - ikhoza kukhala pituitary kapena hypothalamus,
• kagayidwe kachakudya
• extrapancreatic zinthu, monga matenda am'mimba, chiwindi kapena ndulu.

Zomwe, mwachidziwikire, sizingokhala ndi izi ndipo ndikofunikira kuzindikira kusakwanira kwa kudya komanso kupezeka kwa shuga m'magazi. Kusala kudya kwanthawi yayitali, komwe kumalumikizidwa ndi zovuta zina, monga anorexia kapena pyloric stenosis - chithandizo chawo chimalimbikitsidwa kwambiri. Kuphatikiza apo, matendawa amatha kupsinjika, komanso hyperinsulinemia, imatha kutaya mofulumira mafuta. Nthawi zambiri, kusintha kotereku kumadziwika chifukwa cha thupi lanthete kapena ntchito yayikulu. Chifukwa chake, zomwe zimayambitsa kukula kwa mkhalapakati sizowonekera mwachindunji, chifukwa chake ndikufuna kudziwa zomwe zikutchulidwa komanso zowonjezera.

Njira zoyesera

Kuzindikira kumakhazikitsidwa pa chithunzi cha matenda. Zambiri zam'mbuyomu zimaganiziridwa (makamaka, kupangika kwa matenda a hypoglycemic m'mawa kwambiri, ngati chakudya chotsatira sichinasoweke, ndikuwonetsedwa kwa boma pambuyo podziwika kwa chakudya chamagulu). Njira zina zitha kuganiziridwanso ndipo zomwe zimapezeka chifukwa cha mayeso azidziwitso sizisonyezo zosafunikira kwenikweni.

Pankhaniyi, kuzindikira koyenera kuyenera chisamaliro chapadera, chifukwa hypoglycemia iyenera kusiyanitsidwa ndi mndandanda wonse wamatenda am'mitsempha ndi amisala. Tikuyankhula za khunyu, tetany, psychosis, komanso neurasthenia kapena neoplasm mu ubongo. Matenda ena kapena zotupa zimathanso kukhudza izi.

Polankhula za mitundu ina ya matendawa, ndikofunikira kumvetsetsa kuti amazindikiritsidwa pamaziko azizindikiro zazikuluzikulu komanso zosatsutsika za matenda omwe akuwatsogolera.

Kuphatikiza apo, zosafunikiranso zimaperekedwa m'njira zapadera zofufuzira. Zonsezi zithandizira mtsogolo kuti ayambe kulandira chithandizo choyenera komanso chokwanira.

Kukana insulini

Kuchokera m'magazi, shuga amayenera kulowa m'matimu kuti agwiritsidwe ntchito ngati mafuta mwa iwo. Komabe, pamene ma receptor akulephera kugwira ntchito, chidwi cha insulin chimatsekedwa, ndipo sichitha kugwira ntchito zake.Zotsatira zake, amadziunjikira kwambiri m'magazi.

Izi zimawonekera motere:

• matenda oopsa
• minofu yofewa yatupa,
• Pali kupendekera ndi kuchuluka kwa ngalawa,
• kunenepa kwambiri kumayamba,
• arteriosulinosis imachitika.

Izi zimawonjezera chiopsezo cha odwala omwe samadalira insulin, mtima ndi ma strokets. Matendawa amatha kubweretsa kulumala kapena kufa kwa wodwalayo.

Kodi hyperinsulinemia ndi polycystosis amathandizidwa bwanji?

Ngati mayi ali ndi matendawa, ndikofunikira kuti amupatse zakudya zomwe azidzayamwa ndi adotolo komanso kulandira chithandizo chokwanira.

Ntchito yayikulu pamenepa ndi kubweretsa kulemera kwa chizolowezi.

Pachifukwachi, calorie amaletsa chakudya chama calories 1800 patsiku, chakudya chomwe chili ndi shuga wambiri pamenepa chizichita ngati mtundu wa chithandizo. Ndikofunika kuchepetsa kugwiritsa ntchito momwe mungathere:

Chakudya chimatengedwa pang'onopang'ono 6 pa tsiku. Komanso chithandizo, mankhwala a mahomoni, kutikita minofu ndi hydrotherapy titha kudziwa. Njira zonse ziyenera kuchitika moyang'aniridwa ndi dokotala.

Matenda ambiri osachiritsika nthawi zambiri amakhala isanayambike matenda ashuga.

Mwachitsanzo, hyperinsulinemia mwa ana ndi akulu imapezeka kawirikawiri, koma ikuwonetsa kupanga kwa mahomoni ambiri omwe angapangitse kuchepa kwa shuga, kusowa kwa mpweya ndi kuperewera kwa dongosolo lonse lamkati. Kuperewera kwa njira zochizira zomwe cholinga chake kupondereza kupanga insulin zingayambitse kukula kwa matenda osokoneza bongo.

Momwe mungadziwire matenda?

Kuzindikira kwa hyperinsulinemia ndikovuta kochepa chifukwa chosowa kutsimikizika kwa chizindikirocho komanso kuti mwina sangawonekere mwachangu. Kuti mudziwe izi, njira zotsatirazi zoyeserera zimagwiritsidwa ntchito:

• kutsimikiza kwa kuchuluka kwa mahomoni m'magazi (insulin, ma pituitary ndi mahomoni a chithokomiro),
• MRI ya pituitary gland yothandizirana ndi vuto lina kuti atulutse chotupacho,
• Ultrasound yam'mimba, makamaka, kapamba,
• Ultrasound yamchiberekero cha ziwalo za azimayi (kukhazikitsa kapena kupatula ma concomitant gynecological pathologies omwe mwina ndi omwe amachititsa kuti insulin iwonjezeke m'magazi),
• kuthamanga kwa magazi (kuphatikiza kuwunikira tsiku lililonse pogwiritsa ntchito wowunika Holter),
• kuyang'anira pafupipafupi shuga (pamimba yopanda kanthu komanso katundu).

Pazifukwa zokayikitsa pang'ono, muyenera kulumikizana ndi endocrinologist, popeza kupezeka kwa nthawi yayitali kwa matenda kumawonjezera mwayi wakuchotsa kwathunthu

Kuchoka kulephera mu ndulu ya pituitary

Chilengedwe cha pituitary ndi dipatimenti muubongo yomwe imayang'anira kupanga mahomoni ofanana. Ngati zakuphwanya zikuchitika mu ntchito yake, kuchepa kwawo kapena zochulukirapo zimachitika.

Zoyambitsa zazikulu ndizomwe zimayambitsa matendawa, motero takambirana pamwambapa.

Zina mwa izi ndi izi:

• chikomokere ndi uchidakwa
• moyo wongokhala, ndiko kuti, kusachita zinthu zolimbitsa thupi,
• ukalamba
• atherosulinosis
• matenda oopsa
• kunenepa
• chibadwa.

Mwamwayi, zambiri mwazomwe zimayambitsa zimatha kukhudzidwa.

Timapereka kuchotsera kwa owerenga tsamba lathu!

Kuzindikira ndi kuchiza matenda a hypoglycemic

Choyamba, kupezeka kwa matendawa kumatengera kuwonekera kwakanthawi kachipatala. Nthawi zambiri, matenda atha kumayikiridwa pokhapokha ngati akudandaula kuchokera kwa wodwala. Komabe, ndikofunikira kuchita zowunikira tsiku lililonse zamagulu a shuga, komanso mayeso osiyanasiyana ogwira ntchito. Kuphatikiza apo, kufotokozera mtundu wa kuphwanyidwa, njira zofunikira zowunikira ziwalo zamkati, kuphatikizapo kapamba, zimayikidwa.

Ngati kuchuluka kwa insulini kudayamba chifukwa cha zotupa zomwe zimapezekanso m'mapapo, ndikofunikira kuti azichotsa. Ndi yachiwiri chikhalidwe cha matenda, chithandizo cha matenda oyamba ayenera kuthana nawo. Pakakhala vuto, ndikulimbikitsidwa kudya zakudya zamafuta zilizonse othamanga, monga shuga.

Pochiza matenda a magwiridwe antchito a matendawa, kuopsa kwa matendawa, kutha kwa zovuta kuntchito ya ziwalo zina, komanso zovuta za mankhwalawa zimawerengedwa. Zonsezi zimabweretsa kuti odwala amalimbikitsidwa kudya kwapadera, komwe sayenera kuphwanya. Zakudya zopatsa thanzi kwa hyperinsulinism ziyenera kukhala zofunikira mokwanira, zokhala ndi chakudya chovuta kwambiri. Kudya kumakutambika mpaka 5-6 patsiku.

Momwe mungaperekere thandizo loyamba

Kukhala pafupi ndi munthu yemwe wapanga insulin yayikulu kulowa m'magazi, chinthu chachikulu sikuti kuchita mantha. Kuti muchepetse mkhalidwe wa wodwalayo, chotsani zizindikiro zoyambirira za kuukiridwa, muyenera kum'patsa maswiti okoma, kutsanulira tiyi wokoma. Zikatayika, gwiritsani ntchito shuga mwachangu.

Vutolo litasintha ndipo palibe chizindikiro chobwereza, wodwalayo amayenera kupita kuchipatala kapena akatswiri atchedwe kunyumba. Zodabwitsazi sizinganyalanyazidwe, munthu amafunika chithandizo, mwinanso kuchipatala mwachangu, izi ziyenera kumvetsedwa.

Ndi matenda omwe adapezeka koyambirira, wodwalayo ali ndi mwayi uliwonse wochotsa iye kwamuyaya. Mwambiri, matendawa ndi abwino, chifukwa hyperinsulinemia imapezeka bwino ndipo imatha kupezeka.

Kodi polycystic ndi hyperinsulinemia amawonetsedwa bwanji?

Hyperinsulinemia imadziwika ndi maphunziro aposachedwa, koma nthawi zina, odwala amatha kuzindikira kufooka kwa minofu, kuzizira, chizungulire, ludzu lokwanira, kusakhazikika kwa chidwi, ulesi, ndi kutopa kosalekeza, zizindikiro zonsezi ndizovuta kuphonya, kuwonjezera apo, kuzindikira nawo amapita patsogolo kwambiri.

Ngati tizingolankhula za polycystosis, zizindikiro zake zazikulu zimawonetsedwa ndi kusakhalapo kapena kusakhazikika kwa msambo, kunenepa kwambiri, hirsutism ndi androgenic alopecia (dazi), ndipo kuwonetsa kulikonse kumafunikira chithandizo cha munthu payekha.

Nthawi zambiri, kusagwira bwino ntchito kwa thumba losunga mazira kumatsatiridwa ndi ziphuphu, kukakamira, zilembo zowoneka pamimba, kutupa, kupweteka pamimba. Kuphatikiza apo, mkazi amatha kuwona zotsatirazi ndikuwonetsa:

• kusintha kwamphamvu
• kupuma kwamphamvu kugona (apnea),
• mantha
• kuchuluka kwa mkwiyo
• kukhumudwa
• kugona
• mphwayi.

Ngati wodwala apita kwa dokotala, ndiye kuti malo oyamba azikhala pamakina a ultrasound, omwe angapangitse mawonekedwe ambiri a cystic, kukula kwa kaphatikizidwe ka ovarian, endometrial hyperplasia mu chiberekero. Njira zoterezi zimatsatiridwa ndikumverera kowawa pamimba yotsika ndi m'chiuno, ndipo zomwe zimayambitsa ziyenera kukumbukiridwa.

Ngati simukugwirizana ndi chithandizo cha polycystic cha panthawi yake, ndiye kuti mkazi amatha kuzindikira zovuta zazikulu:

• khansa yam'mimba
• hyperplasia
• kunenepa
• khansa ya m'mawere
• kuthamanga
• matenda ashuga
• thrombosis
• sitiroko
• thrombophlebitis.

Kuphatikiza pa izi, zovuta zina za matendawa zimatha kukhazikika, mwachitsanzo, kulowetsedwa m'mimba, kupweteka kwamimba, kubadwa msanga, thromboembolism, komanso dyslipidemia.

Polankhula manambala, kuchokera pa 5 mpaka 10 peresenti ya azimayi amisinkhu yosabereka amakhala ndi vuto losunga mazira a polycystic, ngakhale kuti zomwe zimayambitsa vutoli ndizodziwika.

Kodi matendawa ndi oopsa bwanji?

Matenda amtundu uliwonse angayambitse zovuta ngati palibe chochitika munthawi yake. Hyperinsulinemia sikuti ndi yosiyana, motero, imayendetsedwa ndi zotsatira zowopsa. Matendawa amatuluka pachimake komanso matenda osachiritsika. Kuphunzira kumene kumapangitsa kuti zinthu za mu ubongo ziwonongeke, zomwe zimakhudza gawo la psychosomatic.

• zosokoneza pakugwira ntchito kwamakina ndi ziwalo zamkati,
• chitukuko cha matenda ashuga
• kunenepa
• chikomokere
• kusokera mu ntchito yamtima wamtima,
• encephalopathy
• parkinsonism

Hyperinsulinemia yomwe imachitika paubwana imakhudza kukula kwa mwana.

Zovuta zotheka

Hyperinsulinism imatha kubweretsa zovuta zazikulu komanso zosasinthika zomwe sizigwirizana ndi moyo wa wodwalayo.

Zovuta zazikulu za matendawa:

• sitiroko
• vuto la mtima
• chikomokere
• mavuto amakumbukidwe ndi kuyankhula,
• parkinsonism
• encephalopathy
• matenda ashuga
• kunenepa.

Izi zimatengera kudwala kwamatenda komanso zomwe zimachitika. Ngati chotupa chowoneka chikupezeka, makulidwe amachotsedwa, ndipo wodwalayo amachira milandu 90%. Ndi kuvulala kwa neoplasm komanso kulephera kugwira ntchito, kuchuluka kwa kupulumuka kumakhala kotsika.

Congenital Hyperinsulinism

Mankhwala amakono amagwiritsa ntchito mawu akuti congenital hyperinsulinism, ndipo matenda amapezeka mwa akhanda ndi makanda. Zomwe zimayambitsa matendawa sizimadziwika, chifukwa chake madokotala amati kubadwa mwatsopano, vuto la majini limakhudzanso. Fomuyi imatchedwanso idiopathic hyperinsulinism, zizindikiro zake sizitchulidwanso kwambiri.

Congenital Hyperinsulinism

Kodi njira zamankhwala ndi ziti?

Chithandizo cha hyperinsulinemia chimayamba ndi chithandizo cha zomwe zimayambitsa. Izi ndizowona makamaka ngati vuto lanu likuyambitsa insulinoma kapena nesidioblastosis.

Chithandizo chanu chitha kuphatikizaponso mankhwala, kusintha kwa moyo, komanso mwina opaleshoni.

Mankhwala omwe amagwiritsidwa ntchito pochiza matenda awa ali ofanana kapena ofanana ndi mankhwala omwe amagwiritsidwa ntchito pochiza matenda ashuga. Komabe, mankhwalawa amayenera kugwiritsidwa ntchito pokhapokha ngati kudya komanso kuchita masewera olimbitsa thupi sikokwanira kuthana ndi vutoli.

Mankhwala ena amathandizira kuti vutoli lithe. Ndikofunikira kukambirana ndi mankhwala onse ndi dokotala. Ndikofunikanso kuti madokotala anu onse adziwe zamankhwala onse omwe mumamwa komanso zikhalidwe zanu zonse zamankhwala.

Chitani masewera olimbitsa thupi

Kuchita masewera olimbitsa thupi kapena kuchita masewera olimbitsa thupi kungakhale kothandiza pakulimbitsa thupi lanu kuti mumve insulini. Kusintha kumeneku kumachepetsa kukana kwa insulini, chomwe chimayambitsa hyperinsulinemia. Kuchita masewera olimbitsa thupi kumathandizanso kuchepetsa kunenepa kwambiri, komwe kungakhale chifukwa chachikulu cha izi.

Fotokozerani mitundu ya masewera olimbitsa thupi omwe muyenera kuyesa kuthandizira ndi dokotala. Izi ndichifukwa choti masewera ena olimbitsa thupi kapena kulimba kwazinthu zina zolimbitsa thupi zomwe zingakulitse vuto lanu, mmalo moziwongolera.

Pali mitundu iwiri yayikulu yochita zolimbitsa thupi yolimbikitsidwa pochiza hyperinsulinemia. Izi ndi:

• kukana zolimbitsa thupi. Mtunduwu umayang'ana gulu limodzi la minofu nthawi. Izi ziyenera kuphatikizapo kubwereza pang'ono komanso nthawi yayikulu yopumira pakati pawo.
• Zochita zolimbitsa thupi za aerobic. Cholinga chanu chizikhala chofatsa komanso chothandiza kwambiri pazotsatira zabwino kwambiri. Masewera ena olimbitsa thupi omwe amapangitsa kuti munthu akhale ndi vutoli ndi monga kuyenda, kusambira, ndi kuthamanga.

Kuchita masewera olimbitsa thupi a HIIT ndikulimbikitsidwa. Umu ndi mtundu wa masewera olimbitsa thupi. Imasinthasintha pakati pama seti apamwamba komanso mwamphamvu kwambiri komwe kumathandizira kuchira.

Zakudya ndizofunikira kwambiri pa chithandizo chilichonse, komanso mankhwalawa a hyperinsulinemia. Kudya zakudya zopatsa thanzi kumathandizanso kuti thupi lanu lizigwira ntchito bwino komanso kuti muchepetse kunenepa kwambiri. Zitha kuthandizanso kuwongolera shuga ndi insulin.

Pali zakudya zitatu zomwe amakonda kudya za glycemic control ndi hyperinsulinemia. Izi ndi:

• Zakudya zaku Mediterranean
• zakudya zamafuta ochepa
• Zakudya zamafuta ochepa

Zakudya izi zimatha kukuthandizani kuyendetsa glycemic, komwe kumapangitsa mayankho anu a insulin kuthupi. Zakudya zomanga thupi kwambiri ziyenera kupewedwa. Zakudya zambiri zama protein zimatha kuthandiza ndi mitundu ina ya matenda ashuga, koma zimatha kuwonjezera hyperinsulinemia.

Chilichonse mwazakudya izi chimakhala makamaka zipatso, tirigu wathunthu, masamba, fiber ndi nyama yopendekera. Onetsetsani kuti mwakambirana zosintha zamtundu uliwonse wazakudya musanayambe dongosolo latsopano lazakudya.

Zoyambitsa matenda

Hyperinsulinism mu terminology yamankhwala imadziwika kuti ndi matenda a matenda, zomwe zimachitika motsutsana ndi maziko a kuchuluka kwambiri kwa insulin.

Munthawi imeneyi, thupi limachepetsa phindu la shuga m'magazi. Kuperewera kwa shuga kumatha kupangitsa kuti mpweya uzikhala ndi ubongo, womwe ungayambitse kuti ntchito yamanjenje iwonongeke.

Hyperinsulism nthawi zina imakhala popanda chiwonetsero chapadera chazachipatala, koma nthawi zambiri matendawa amabweretsa kuledzera kwambiri.

1. Congenital Hyperinsulinism. Zimatengera kutengera kwa chibadwa. Matendawa amakula motsutsana ndi maziko a matenda omwe amapezeka m'matumbo omwe amalepheretsa kupangika kwama mahomoni.
2. Second Hyperinsulinism. Fomuyi imapita patsogolo chifukwa cha matenda ena omwe apangitsa kuti mahomoni azitha kutulutsa. Ntchito hyperinsulinism imakhala ndi mawonetseredwe omwe amaphatikizidwa ndi kupuwala kwa metabolism ndipo amadziwika ndi kuwonjezeka kwadzidzidzi kwa glucose.

Zinthu zazikulu zomwe zingayambitse kuchuluka kwa mahomoni:

• maselo achikondwerero opanga insulin yosayenera ndi kupangika kosadziwika komwe sikumadziwika ndi thupi,
• kukana, zomwe zimapangitsa kuti mahomoni asamalamulire,
• kusunthika pakugawa shuga m'magazi,
• onenepa kwambiri
• atherosulinosis
• chibadwire
• anorexia, yomwe ili ndi chikhalidwe cha neurogenic ndipo imalumikizidwa ndi lingaliro lowona mopepuka la kunenepa kwambiri kwa thupi,
• zochita za oncological pamimba,
• zoperewera komanso zosapatsa thanzi,
• kuvutitsidwa kwa maswiti, zomwe zimapangitsa kuti glycemia iwonjezeke, ndipo, chifukwa chake, kuchuluka kwa katulutsidwe ka mahomoni.
• matenda a chiwindi
• mankhwala osavomerezeka a insulini kapena kumwa kwambiri mankhwala osokoneza bongo kuti muchepetse shuga, zomwe zimabweretsa mawonekedwe a hypoglycemia,
• endocrine pathologies,
• osakwanira enzyme zinthu nawo metabolic njira.

Zomwe zimayambitsa hyperinsulinism sizitha kudziwonetsa kwa nthawi yayitali, koma panthawi imodzimodzi zimayipitsa ntchito ya chiwalo chonse.

Malangizo othandiza

Kuti muchepetse kuwonetsa kwa hyperinsulinemia, ndikofunikira kuyang'anitsitsa njira ya matenda ashuga ndikutsatira malangizo akuluakulu:

• idyani pang'ono komanso moyenera
• Nthawi zonse onani kuchuluka kwa glycemia, sinthani ngati pakufunika,
• samalani njira yoyenera yomwera,
• khalani ndi moyo wathanzi.

Ngati kuphatikiza kwa insulin kwambiri chifukwa cha matenda enaake, ndiye kuti kupewetsa khunyu kumachepetsedwa ku chithandizo cha matenda am'mimba, omwe amakhala ngati chifukwa chachikulu cha mawonekedwe awo.

Makanema okhudzana nawo

Kodi hyperinsulinism ndi njira yochotsera nthawi zonse njala, mutha kudziwa kanema uyu:

Titha kunena za hyperinsulinism kuti uwu ndi matenda omwe ungayambitse zovuta zazikulu. Amakhala ngati mtundu wa hypoglycemia.M'malo mwake, matendawa ndi omwe amasiyana kwambiri ndi matenda ashuga, chifukwa ndi omwe amapangika insulin kapena kupezeka kwake kwathunthu, ndipo ndi hyperinsulinism imachulukitsidwa kapena mtheradi. Kwenikweni, kuzindikira kumeneku kumapangidwa ndi gawo la akazi.

• Amachotsa zoyambitsa zovuta
• Imachepetsa kupanikizika mkati mwa mphindi 10 pambuyo pa kutsata

Kodi kuchuluka kwawonjezereka kapena kuwonjezereka kwamankhwala a insulin m'magazi.

Kuchuluka kwa timadzi timeneti kumapangitsa kuchuluka kwa shuga, komwe kumapangitsa kuti shuga achepetse, komanso kumayambitsa kuperewera kwa mpweya waubongo, komwe kumayambitsa vuto la manjenje.

Matendawa amafala kwambiri mwa akazi ndipo amapezeka azaka za 26 mpaka 55. Kuukira kwa hypoglycemia, monga lamulo, kumawonekera m'mawa pambuyo pothamanga mokwanira. Matendawa amatha kugwira ntchito ndipo amadzionetsera nthawi yomweyo, masana.

Hyperinsulinism imatha kupangitsa kuti anthu azikhala ndi njala nthawi yayitali. Zina zofunika pakuwonetsa matendawa zimatha kukhala zochitika zosiyanasiyana zolimbitsa thupi komanso zokumana nazo m'maganizo. Mwa akazi, zizindikiro zobwereza za matendawa zimachitika pokhapokha ngati nthawi yotsala isanakwane.

Zizindikiro za Hyperinsulinism zili ndi izi:

• njala yosatha
• kutuluka thukuta kwambiri
• kufooka wamba
• tachycardia
• womvera
• paresthesia
• diplopia
• kumakhala ndi mantha osaneneka
• kusokonezeka kwa malingaliro
• kugwedezeka kwa manja ndi miyendo yake,
• zochita zosakhudzidwa
• dysarthria.

Komabe, zizindikirazi ndi zoyambira, ndipo ngati simungazichiritse ndikupitiliza kunyalanyaza matendawa, zotsatira zake zimakhala zokulirapo.

Mtheradi hyperinsulinism imawonetsedwa ndi zizindikiro zotsatirazi:

• kulephera kwadzidzidzi
• coma ndi hypothermia,
• coma ndi hyporeflexia,
• tonic kukokana
• kukokana kwamankhwala.

Kukodwa koteroko kumachitika kaŵirikaŵiri pambuyo poti mwadzidzidzi mwadzidzidzi.

Asanayambe kuukira, zizindikiro zotsatirazi zimawonekera:

• utachepetsa kukumbukira
• kusakhazikika mtima
• kunyalanyaza kwathunthu ena
• kutayika kwa maluso aukadaulo,
• paresthesia
• Zizindikiro za kuperewera kwa piramidi,
• zamatsenga.

Chifukwa cha chizindikiro, chomwe chimapangitsa kuti anthu azikhala ndi njala nthawi zambiri, munthu nthawi zambiri amakhala wonenepa kwambiri.

Matenda a kapamba

Ntchito yake yopitilira imayambitsa kuvala komanso kusokoneza kwakukulu.

Izi sizikuwonetsedwa kokha mu kayendedwe ka shuga wamagazi, komanso kapangidwe kazakudya.

Matenda a mtima

Kukula kwa atherosulinosis kumabweretsa kuwoneka kwa cholesterol malo, omwe samangoleketsa kuwunikira kwa ziwiya, komanso amawonongera makoma awo. Zotsatira zake, misozi imatha. Izi zimawonjezera chiopsezo cha matenda a mtima ndi mikwingwirima. Matendawa amatha kubweretsa kulumala kapena kufa kwa wodwalayo.

Kuthiridwa kwa kuchuluka kwa chakudya panthawi ya hyperinsulinemia kumabweretsa kudzikundikira kwa mafuta apadera amtundu - triglycerides. Samangoyambitsa kulemera kochulukirapo, komanso amavulaza thupi, zomwe zimathandizira kumasulidwa kwa mahomoni owonjezera.

Mulinso zinthu zotsatirazi.

Mankhwala

Kusankha kwa njira zamankhwala kumatsimikiziridwa ndi mtundu wa hyperinsulinemia, digiri yake, kupezeka kwa matenda oyanjana komanso chidwi cha wodwalayo pamankhwala ena.

Mankhwala omwe amalembedwa omwe amathandizira mtima, mitsempha yamagazi, kapamba, kutulutsa kwa pituitary, dongosolo la kubereka kwa akazi.

Mankhwala othandizira

Zakudya zoyenera, zomwe zimaphatikizapo zipatso, masamba, chimanga ndi zitsamba ndizofunikira kwambiri kwa wodwalayo.

Ndi matenda omwe adapezeka koyambirira, wodwalayo ali ndi mwayi uliwonse wochotsa iye kwamuyaya. Mwambiri, matendawa ndi abwino, chifukwa hyperinsulinemia imapezeka bwino ndipo imatha kupezeka.