Ciprolet® (250 mg) Ciprofloxacin

  • mapiritsi okhala ndi filimu: biconvex yozungulira, yokhala ndi mawonekedwe osalala, chigoba ndi pakati pa cholembapo chimakhala choyera kapena choyera (zidutswa 10 chilichonse pachimake, pamakatoni a 1 kapena 2 matuza),
  • kulowetsedwa: kopanda maonekedwe achikasu kapena owala achikasu (100 ml aliyense mu botolo la pulasitiki, botolo imodzi mu mtolo wa makatoni),
  • Diso loyera: chikasu chowoneka chikaso kapena chamadzimadzi chosatulutsa (5 ml iliyonse mu botolo la pulasitiki, botolo 1 mu mtolo wa makatoni).

Piritsi limodzi lili:

  • yogwira mankhwala: ciprofloxacin hydrochloride - 291.106 mg kapena 582.211 mg, womwe ndi wofanana ndi 250 mg kapena 500 mg wa ciprofloxacin (motsatana),
  • othandizira zigawo: croscarmellose sodium, wowuma chimanga, colloidal silicon dioxide, cellcrystalline cellulose, magnesium stearate, talc,
  • kapangidwe kazipolopolo: sorbic acid, hypromellose (6 cps), macrogol 6000, polysorbate 80, titanium dioxide, dimethicone, talc.

1 ml yankho lili:

  • yogwira mankhwala: ciprofloxacin - 2 mg,
  • othandizira: hydrochloric acid, sodium chloride, lactic acid, disodium edetate, sodium hydroxide, citric acid monohydrate, madzi a jekeseni.

1 ml akutsikira muli:

  • yogwira mankhwala: ciprofloxacin hydrochloride - 3,49 mg, womwe ndi wofanana ndi 3 mg wa ciprofloxacin,
  • othandizira zigawo: disodium edetate, 50% yankho la benzalkonium chloride, hydrochloric acid, sodium kolorayidi, madzi a jekeseni.

Mapiritsi okhala ndi mafilimu ndi njira yothetsera

Kugwiritsa ntchito Ciprolet mwanjira ya mapiritsi ndi yankho kumawonetsedwa pochiza matenda opatsirana komanso otupa omwe amayambitsidwa ndi tizilombo tating'onoting'ono tokhudza chiprofloxacin, kuphatikizapo:

  • matenda a mano, mkamwa, nsagwada, m'mimba,
  • matenda a khutu, mphuno ndi mmero,
  • matenda kupuma thirakiti
  • matenda a gallbladder ndi biliary thirakiti,
  • matenda a impso ndi kwamkodzo
  • matenda a musculoskeletal,
  • matenda a mucous nembanemba, khungu ndi zofewa zimakhala,
  • matenda obwera pambuyo pake
  • matenda amtundu (prostatitis, chinzonono, adnexitis),
  • sepsis
  • peritonitis.

Kuphatikiza apo, mapiritsi ndi yankho zimagwiritsidwa ntchito ngati gawo la zovuta la mankhwala okhala ndi ma immunosuppressants popewa komanso kuchiza matenda kwa odwala omwe ali ndi chitetezo chokwanira.

Diso limatsika

Kugwiritsa ntchito madontho kukuwonetsedwa pochiza matenda amtundu wa m'maso ndi zotupa zomwe zimayambitsidwa ndi mabakiteriya omwe amakhudzidwa ndi mankhwalawa:

  • subacute ndi pachimake conjunctivitis,
  • blepharoconjunctivitis, blepharitis,
  • zilonda zam'mimba za etiology,
  • keratoconjunctivitis, keratitis ya bakiteriya,
  • aakulu mawonekedwe a meibomite ndi dacryocystitis,
  • zovuta pambuyo opaleshoni,
  • zovuta zakupweteka pambuyo pakuvulala kwa maso kapena thupi lakunja likulowa (kuphatikiza kupewa kwawo).

Kuphatikiza apo, madontho amagwiritsidwa ntchito mu opaleshoni ya ophthalmic popewa kugwira ntchito.

Contraindication

  • nthawi ya pakati komanso yoyamwitsa,
  • kusalolera kwa fluoroquinolone kukonzekera gulu,
  • Hypersensitivity pamagawo a mankhwala.

Mochenjera, Cyprolet iyenera kutumikiridwa chifukwa cha matenda amisempha (ubongo), ngozi ya m'matumbo, matenda opatsirana.

Kuphatikiza apo, pezani zotsutsana pamtundu uliwonse wa mitundu.

Kulowetsedwa njira

Njira yothetsera vutoli idapangidwa kuti ikulowetsedwe kwamtambo (iv) kukapanda kuleka.

Njira yothetsera imatha kusakanikirana ndi 0,9% sodium chloride solution, 10% solution ya fructose, 5% ndi 10% dextrose yankho, yankho la Ringer, yankho la 5% dextrose yankho ndi 0,2525% kapena 0,45% sodium chloride solution.

Mukamapereka mankhwala, kuchuluka kwa matenda, mtundu wa matenda, momwe muliri, msinkhu ndi kulemera kwa wodwala, matendawa amafunika kuiganizira.

Kutalika kwa kulowetsedwa kuyenera kukhala pamlingo wa 0,5 maola pakukhazikitsa 200 mg ya mankhwalawa.

Mlingo woyenera: matenda opatsirana - 200 mg kawiri kugogoda, kwambiri - 400 mg 2 kawiri pa tsiku. Kutalika kwa mankhwalawa ndi masiku 7-14 kapena kuposerapo.

Mu chinzonono chachikulu, wodwala amapatsidwa 100 mg kamodzi.

Kupewa matenda a postoperative kumachitika chifukwa cha kuperekera kwa 200-400 mg ya mankhwalawa 0.5-1 maola asanafike opareshoni.

Malangizo apadera

Chifukwa cha chiwopsezo cha mavuto obwera kuchokera ku dongosolo lamkati la mankhwalawa, odwala omwe ali ndi mbiri ya kukomoka, kukomoka, khunyu, kuwonongeka kwa ubongo, komanso zotupa zam'mitsempha zimatha kutumizidwa Ziprolet kokha chifukwa cha thanzi.

Ngati kutsegula m'mimba kwambiri ndikuwonekera kwakanthawi yamankhwala kumachitika, ndikofunikira kupatula kukhalapo kwa pseudomembranous colitis, kuti mutsimikizire za matenda, kusiya mapiritsi ndi njira yofunikira ndikofunikira.

Chifukwa cha kutukusira kwa tendon kapena kutupuka kwawo chifukwa chogwiritsa ntchito mapiritsi ndi njira yothetsera mankhwalawa, chithandizo chiyenera kusiyidwa pomwe zizindikiro zoyambirira za tendovaginitis kapena kupweteka kwa tendons zimawonekera.

Pakamwa ndi makolo makonzedwe a mankhwalawa amayenera kutsagana ndi kuchuluka kwa madzimadzi ambiri odwala omwe ali ndi diureis yachibadwa.

Pa mankhwala, tikulimbikitsidwa kupewa dzuwa.

Osavala magalasi ogwiritsa ntchito mukamagwiritsa ntchito madontho.

Mawonekedwe amaso sangayikidwe mu chipinda chakunja cha diso kapena subconjunctivally.

Pogwiritsa ntchito munthawi yomweyo njira zina zothandizira kupumula, kusiyana pakati pa njirazo kuyenera kukhala kwa mphindi 5 kapena kupitirira.

Kugwiritsidwa ntchito kwa Tsiprolet kumapangitsa kuti wodwala azitha kuyendetsa magalimoto ndi zida zake.

Kuyanjana kwa mankhwala

Pogwiritsa ntchito nthawi yomweyo ya Cyprolet:

  • didanosine amachepetsa mayamwidwe a ciprofloxacin,
  • theophylline imatha kuonjezera ndende ya plasma ndi chiopsezo chokhala ndi poizoni.
  • mankhwala omwe ali ndi aluminium, zinc, iron kapena magnesium ion, ndi maantacidine amatha kuchepetsa kuyamwa kwa ciprofloxacin, kotero, nthawi yopereka pakati pa mankhwalawa iyenera kukhala osachepera maola 4,
  • cyclosporin imathandizira mphamvu yake ya nephrotoxic,
  • antimicrobials (aminoglycosides, beta-lactams, clindamycin, metronidazole) amachititsa synergistic zotsatira,
  • Mankhwala osapweteka a antiidal (kuphatikiza acetylsalicylic acid) amawonjezera kugwidwa,
  • metoclopramide imathandizira kuyamwa kwa ciprofloxacin,
  • uricosuric wothandizila kuonjezera plasma ndende ya ciprofloxacin,
  • anticoagulants osagwirizana amathandizira kusintha kwawo, kukulitsa nthawi yotuluka magazi.

Kuphatikizika komwe kunathandizira matenda ena:

  • matenda oyambitsidwa ndi Pseudomonas spp: azlocillin, ceftazidime,
  • Matenda a streptococcal: meslocillin, azlocillin ndi mankhwala ena a beta-lactam,
  • staph matenda: isoxazolylpenicillins, vancomycin,
  • Matenda a anaerobic: metronidazole, clindamycin.

Acidity (pH) ya kulowetsedwa kwa ciprofloxacin ndi 3.5-4.6; chifukwa chake, ndizosagwirizana ndi zamankhwala zomwe sizigwirizana ndi mayankho osakhazikika komanso kukonzekera. Pakulamula kwa iv, ndizosatheka kusakanikirana ndi mayankho ndi pH yoposa 7.

Mafanizo a Ciprolet ndi awa: mapiritsi - Ciprofloxacin, Cifran, Ciprinol, Ciprobay, mayankho - Ififpro, Ciprobid, Quintor, akutsikira - Cipromed, Rocip, Ciprofloxacin-AKOS.

Mapiritsi ndi yankho la kulowetsedwa

Matenda opatsirana komanso otupa omwe amayambitsidwa ndi tizilombo tating'onoting'ono tomwe timayang'ana ciprofloxacin.

  • matenda am'munsi kupuma thirakiti (chibayo, bronchiectasis, bronchitis pachimake ndi kufalikira kwa chifuwa, matenda a cystic fibrosis),
  • Matenda a ENT (pachimake sinusitis),
  • matenda a impso ndi kwamikodzo thirakiti (cystitis, pyelonephritis),
  • matenda amtundu
  • bakiteriya matenda am'mimba (m'mimba thirakiti, m'mimba thirakiti),
  • matenda a pakhungu ndi minyewa yofewa: zilonda zopatsirana, mabala, zilonda zam'mimba, zilonda zam'mimba,
  • matenda oyambitsidwa ndi kuchepa kwa magazi pakumwa ma immunosuppressants, komanso kwa odwala omwe ali ndi neutropenia,
  • sepsis
  • peritonitis
  • matenda a mafupa ndi mafupa: septic nyamakazi, osteomyelitis,
  • kupewa ndi kuchiza matenda am'mapapo.

Ana kuyambira wazaka 5 mpaka 17:

  • mankhwala a mavuto a Pseudomonasaeruginosa ana okhala ndi pulmonary cystic fibrosis,
  • kupewa ndi kuchiza matenda a pulmonary anthrax (Bacillusanthracis).

Kuphatikiza apo, pa kulowetsedwa: zovuta zamkati mwa m'mimba (kuphatikiza ndi metronidazole), kuphatikizapo shigellosis, matenda am'mimba, typhoid fever, peritonitis, campylobacteriosis, kupewa matenda pakachitika opaleshoni.

Diso limatsika

Matenda opatsirana a maso ndi zida zake zoyambitsidwa ndi tizilombo tating'onoting'ono ta mankhwala:

  • pachimake ndi subacute conjunctivitis,
  • blepharoconjunctivitis,
  • blepharitis
  • zilonda zam'magazi,
  • bakiteriya keratitis ndi keratoconjunctivitis,
  • aakulu dacryocystitis ndi meibomites.

Kupewa komanso kuchiza matenda opatsirana pambuyo pakuchita opaleshoni, kuvulala, matupi achilendo.

Mlingo

Mapiritsi Amtambo, 250 mg, 500 mg

Piritsi limodzi lili

ntchito yogwira - ciprofloxacin 250 mg kapena 500 mg,

obwera: wowuma chimanga, microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, talc yoyeretsedwa, magnesium stearate,

kapangidwe ka chipolopolo: hypromellose, sorbic acid, titanium dioxide, talc yoyeretsedwa, macrogol (6000), polysorbate 80, dimethicone.

Mapiritsi oyera oundana ndi ozungulira, okhala ndi biconvex komanso osalala mbali zonse ziwiri, kutalika kwake (4.10  0.20) mm ndi mainchesi (11.30  0.20) mm (kwa mulingo wa 250 mg) kapena kutalika (5.50  0.20) mm ndi mainchesi ( 12.60  0.20) mm (kwa Mlingo wa 500 mg).

Mankhwala

Pharmacokinetics

Mwamsanga odzipereka kuchokera m'mimba thirakiti. The bioavailability pambuyo pakamwa makonzedwe ndi 70%. Kudya pang'ono kumakhudza mayamwidwe a ciprofloxacin. Mbiri ya plasma ya ndende ya ciprofloxacin yoyendetsera pakamwa imafanana ndi njira yolumikizira makina, chifukwa chake, njira zamkati ndi zamkati zothandizirana zimatha kuonedwa ngati zosinthika. Kuyankhulana ndi mapuloteni a plasma ndi 20 - 40%. Kuthetsa kwa theka-moyo wa ciprofloxacin ndi maola 6 mpaka 8 pambuyo pa limodzi kapena angapo mlingo. Ciprofloxacin imalowa mu ziwalo ndi minyewa: mapapu, mucous membrane wa bronchi ndi sputum, ziwalo zamkati mwa genitourinary system, kuphatikiza ndulu ya prostate, minofu ya mafupa, madzimadzi a cerebrospinal, polymorphonuclear leukocytes, macrophages alveolar. Imagawidwa makamaka ndi mkodzo ndi bile.

Mankhwala

Ciprolet® ndi mankhwala othana ndi zotumphukira kuchokera pagulu la fluoroquinolones. Imaponderezera mabakiteriya a DNA gyrase (topoismerases II ndi IV, omwe amachititsa kuti michere ya DNA ya chromosomal isazunguluke, yomwe ndiyofunika kuti iwerenge zambiri, imasokoneza kaphatikizidwe ka DNA, kukula kwa bakiteriya ndi magawidwe, zimapangitsa kusintha kwamankhwala (kuphatikizira khoma la maselo ndi nembanemba) ndi kufa mwachangu kwa bakiteriya. Imagwira pama grorgan-negative microorganity panthawi yokhala ndi bactericidal komanso nthawi yogawa bactericidal (chifukwa samangokhudza DNA gyrase yokha, komanso imayambitsa kuyang'anitsitsa kwa khoma la cell), ndipo pa gramu-virus yaying'ono imangokhala bactericidal pokhapokha panthawi yogawa. Kuchepetsa kochepa m'maselo a macroorganism amafotokozedwa ndi kusowa kwa DNA gyrase mwa iwo. Ciprolet ® imagwira ntchito molimbana ndi tizilombo tosiyanasiyana tating'onoting'ono tambiri muvitro ndi muvivo:

- aerobic gram zabwino tizilombo: Corynebacterium diphtheriae, Enterococcus faecalis, Listeria monocytogene, Staphylococcus spp. Kuphatikiza Staphylococcus aureus, epermidis, Streptococcus pyogene, agalactiae, chibayo, Streptococcus (magulu C, G), Viroc group.

- aerobic gram-hasi tizilombo tosiyanasiyana: Acinetobacter spp. Kuphatikiza Acinetobacter anitratus, baumannii, calcoaceticus, Actinobacillus Actinomycetemcomitans, Bordetella pertussis, Citrobacter freundii, diversus, Enterobacter spp. parainfluenzae, Helicobacter pylori, Klebsiella spp. Salmonella spp., Serratia spp. Kuphatikiza Serratia marcescens,

- tizilombo toyambitsa matenda a anaerobic: Bifidobacterium spp., Clostridium perfringens, Fusobacterium spp., Peptostreptococcus, Propionibacterium spp., Veillonella spp.,

- michere yama intracellular: Streptococcus pneumoniae, Enterococcus faecalis, Chlamydia pneumoniae, psittaci, trachomatis, Legionella spp. Kuphatikiza ndi Legionella pneumophila, Mycobacterium spp.

Ciprolet ® imagwirizana ndi Ureaplasma urealyticum, Clostridium Hardile, Nocardia asteroids, Bacteroides fragilis, Pseudomonas cepatica, Pseudomonas maltophilia, Treponema pallidum

Zizindikiro zogwiritsidwa ntchito

Matenda osakhazikika komanso ovuta omwe amayamba chifukwa cha tizilombo tomwe timayang'ana ciprofloxacin:

- matenda a ziwalo za ENT (atitis media, sinusitis, frontal sinusitis, mastoiditis, tonsillitis)

- Matenda am'mapapo am'mimba opatsirana omwe amayamba chifukwa cha mabakiteriya osavomerezeka a Klebsiella., Enterobacter spp., Proteus spp., Esherichia coli, Pseudomonas spp., Haemophilus spp., Branhamella spp., Legionella spp, Staphylococcus spp. (kuchulukitsa kwa matenda osakhazikika a m'mapapo, matenda a bronchopulmonary ndi cystic fibrosis kapena bronchiectasis, chibayo)

- matenda amkodzo thirakiti (chifukwa cha gonococcus urethritis ndi cervicitis)

- matenda opatsirana pogonana omwe amayamba chifukwa Neisseriamichere (gonorrhea, chancre wofatsa, urogenital chlamydia)

- epidemiitis orchitis, kuphatikizapo milandu yoyambitsidwa Neisseriamichere.

- kutukusira kwa ziwalo za m'chiuno mwa akazi (matenda otupa a m'chiuno), kuphatikiza milandu yoyambitsidwa Neisseria gonorrhoeae

- matenda am'mimba (bakiteriya matenda am'mimba kapena thirakiti la biliary, peritonitis)

- matenda a pakhungu, minofu yofewa

- septicemia, bacteremia, matenda kapena kupewa matenda omwe ali ndi ofooka chitetezo cha chitetezo (mwachitsanzo, odwala omwe akutenga ma immunosuppressants kapena a neuropenia)

- kupewa ndi kuchiza anthrax ya pulmonary (matenda a Bacillus anthracis)

- matenda a mafupa ndi mafupa

Ana ndi unyamata

- mankhwalawa chifukwa cha Pseudomonas aeruginosa mu ana opitilira zaka 6 ndi cystic fibrosis

- matenda oopsa a kwamikodzo thirakiti ndi pyelonifrita

- kupewa ndi kuchiza matenda a pulmonary anthrax (matenda a Bacillus anthracis)

Mlingo ndi makonzedwe

Mapiritsi a Ciprolet® amalembera achikulire pakamwa, asanadye kapena pakati pa chakudya, osafuna kutafuna, kumwa madzi ambiri. Ikamamwa pamimba yopanda kanthu, zinthu zomwe zimayamba kugwira ntchito zimatengedwa mwachangu. Mapiritsi a Ciprofloxacin sayenera kumwa ndi mkaka (mwachitsanzo, mkaka, yogati) kapena misuzi ya zipatso pophatikiza ndi mchere.

Mlingo umadziwika ndi mtundu komanso kuuma kwa matendawa, komanso chidwi cha pathogen yemwe akuwaganizira, ntchito ya impso ya wodwalayo, komanso mwa ana ndi achinyamata.

Mlingo watsimikiza pamaziko a chizindikirocho, mtundu wake komanso kuopsa kwa matendawa, kudziwa mphamvu za ciprofloxacin, chithandizo chimatengera kuuma kwa matendawa, komanso njira zamankhwala ndi bacteriological.

Pochiza matenda oyambitsidwa ndi mabakiteriya ena (i.e.,Pseudomonas aeruginosa, Acinetobacter kapena Stafilococ) Mlingo wapamwamba wa ciprofloxacin umafunikira ndipo umatha kuphatikizidwa ndi mankhwala amtundu umodzi kapena zingapo zoyenera.

Mankhwalawa matenda ena (mwachitsanzo, matenda otupa a m'chiuno mwa azimayi, matenda amkati, matenda opatsirana omwe ali ndi neutropenia, matenda a mafupa ndi mafupa), kuphatikiza kwa antibacterial imodzi kapena zingapo zogwirizana ndizomwe zimayambitsa. Mankhwala tikulimbikitsidwa Mlingo wotsatira:

Zizindikiro

Mg tsiku lililonse mlingo

Kutalika kwa chithandizo chonse (kuphatikizapo kuthekera kwa chithandizo choyambirira cha makolo ndi ciprofloxacin)

Matenda Ochepa

2 x 500 mg mpaka

Masiku 7 mpaka 14

Matenda opumira kwambiri a m'mapapo

Kuchulukitsa kwa matenda a sinusitis

2 x 500mg kuti

Masiku 7 mpaka 14

Matenda othandizira otitis

2 x 500mg kuti

Masiku 7 mpaka 14

Malignant otitis externa

Kuyambira masiku 28 mpaka miyezi itatu

Matenda amitsempha

2 x 500mg mpaka 2 x 750mg

Azimayi nthawi ya kusintha kwa thupi - kamodzi 500 mg

Cystitis yovuta, pyelonephritis yovuta

2 x 500mg mpaka 2 x 750mg

Osachepera masiku 10 nthawi zina (mwachitsanzo, ndi ma abscesses) - mpaka masiku 21

2 x 500mg mpaka 2 x 750mg

Masabata 2-4 (pachimake), masabata 4-6 (aakulu)

Matenda amtunduwu

Fungal urethritis ndi cervicitis

limodzi mlingo 500 mg

Orchoepididymitis ndi zotupa matenda amchiberekero

2 x 500mg mpaka 2 x 750mg

osachepera masiku 14

Matenda am'mimba komanso matenda amtumbo

Kutsekula m'mimba komwe kumayambitsidwa ndi kachilombo ka bacteria, kuphatikizapo Shigella sppkupatula Shigella dysenteriae lembani I komanso chithandizo champhamvu cha oyenda m'mimba kwambiri

Kutsegula m'mimba chifukwa Shigella dysenteriae lembani Ine

Mapiritsi a Ciprolet (ciprofloxacin) - amathandizira chiyani

Pali matenda ambiri omwe mapiritsi a "Tsiprolet" amagwiritsidwa ntchito. Kuchokera pazomwe amathandizira:

  • Matenda a ENT oyambitsidwa ndi matenda,
  • Tracheitis, bronchitis, chibayo,
  • Cystitis, glomerulonephritis, pyelonephritis, kutupa kwa oreters,
  • Zilonda zam'mimba, mabakiteriya achilengedwe,
  • Matenda opatsirana amafupa ndi mafupa,
  • Matenda am'mimba
  • Kutupa ndi kufalikira khungu.

The zikuchokera mankhwala

Zophatikizira Zocheperako

Chigoba

KugonjeraKulemera mg
Zigawo zikuluzikulu
Cyproxacin hydrochloride291,106
Wokoma50,323
Magnesium wakuba3,514
Colloidal silicon dioxide5
Talcum ufa5
Croscarmellose sodium10
Microcrystalline cellulose7,486
Hypromellose4,8
Titanium dioxide2
Talcum ufa1,6
Macrogol 60001,36
Sorbic acid, polysorbate 80, dimethicone0,08 mg uliwonse

Tsiprolet ndi Tsiprolet A: pali kusiyana

Ciprolet ndi mankhwala othana ndi mankhwala omwe ali amodzi, kuyambira

Chifukwa chake mapiritsi a Cyprolet A akufotokozedwa m'gawoli

ciprofloxacin imagwira ntchito ngati gawo lokhalo la mankhwalawa.

Ciprolet A imadziwika kuti ndi mankhwala ophatikiza. Muli zinthu ziwiri zogwira ntchito - ciprofloxation 500 mg ndi tinisadol 600 mg.

Kuphatikiza kumeneku kumapangitsa kuti ikhale yothandiza kwambiri pochiza matenda osiyanasiyana amtundu wosakanikirana, pomwe tizilombo tosavuta tomwe timalumikizidwa nawo. Mndandanda wazidziwitso ndi zisonyezo zovomerezeka mu Tsiprolet ndi Tsiprolet A ndi zofanana, wachiwiri wokha ndi womwe umagwiritsidwa ntchito pochiza mabakiteriya owopsa komanso otsogola.

Mapiritsi a Cyprolet 250, 500 mg: malangizo ogwiritsira ntchito

Mapiritsiwo amayenera kumwedwa pakamwa pamatumbo athunthu, kutsukidwa ndi madzi pang'ono. Akamwetsedwa pamimba yopanda kanthu, chophatikizacho chimakonzeka mwachangu.

Nthawi yovomerezeka imadziwika ndi zambiri:

  • kukula kwa matendawa
  • mtundu wa matenda
  • pofika zaka
  • mkhalidwe wopanda chitetezo
  • mawonekedwe a impso ndi chiwindi.

Mankhwala a antibacterial samatha atachotsa zizindikiro zosokoneza, tikulimbikitsidwa kumwa mapiritsi masiku ena atatu. Kutalika kwa mankhwala kumatsimikiziridwa ndi adokotala.

Momwe mungamwe Tsiprolet: mlingo

Mlingo woyenera wa akulu:

Mitundu yamatendaMlingo umodzi (mg)Kulandila patsikuMaphunziro Kutalika kwa masiku
Wofatsa pang'ono kupumira matenda opatsirana thirakiti50027-14
Angapo ochepa kupuma thirakiti matenda750
Pachimake sinusitis50010
Wofatsa kuchepetsa matenda a pakhungu ndi zofewa7-14
Zilonda zoperewera zakhungu ndi zofewa750
Wofatsa kuchepetsa matenda a mafupa ndi mafupa50028-42
Matenda owopsa a mafupa ndi mafupa750
Kwamizere thirakiti matenda a matenda250-5007-14
Cystitis yosavomerezeka3
Matenda a prostatitis50028
Gonorrhea Wosavuta250-50011
Zosavomerezeka zam'mimba50025-7
Matenda a typhoid
Monga chithunzi cha zotsatira za opareshoni250-5007
Mankhwalawa sepsis ndi peritonitis500Maola 12 aliwonse7-14
Monga prophylaxis wa anthrax mu mawonekedwe a pulmonary500260
Matenda pa maziko a kukakamizidwa chitetezo chokwanira

(Zotsatira zomwe zidachitika pakumwa mankhwala omwe amachepetsa chitetezo cha mthupi kapena neutropenia).

250-50028

Cyprolet mu mano

Ciprolet imagwiritsidwa ntchito kwambiri mu mano komanso mankhwala ena a antibacterial. Mapiritsi a antibacterial wothandizawa amathandizira kuthana ndi kutupa ndi matenda osiyanasiyana.

Madokotala ati amathandizanso poletsa kupewa kusefukira pambuyo pakuchita opaleshoni.

Pambuyo dzino

Mankhwala othandizira antibacterial amafunikira pambuyo pakuwonjezera mano, komabe, pakuwona kwa mano, atha kuchotsedwa kapena osagwiritsidwa ntchito konse ngati kuchotsedwa kunali kovuta. Mapiritsi a Ciprolet amalembedwa kuti agwiritsidwe ntchito pakadutsa masiku 5 kawiri pa tsiku, piritsi limodzi, lomwe limachepetsa chiopsezo cha kutupa, kupitilira ndi matenda.

Pazino

Mankhwala a Ciprolet pamene alowa m'thupi amayamba kukhala okangalika m'mwazi. Mapiritsi amachotsa msanga kupweteka, amachepetsa kutupa ndikuwononga tizilombo toyambitsa matenda. Mankhwalawa amakhala kwa maola 4-5, kenako amamuthira impso, pomwe adatchuka komanso kugwiritsa ntchito ambiri.

Maantibayotiki ndi othandizira flux m'magawo oyamba, pamene chinyengo sichinachitike, ndiye Ciprolet iyenera kugwiritsidwa ntchito mutangotsegula mapangidwe. Njira yokhazikika yochizira ndi masiku 5, piritsi 1 lililonse 12 maola.

Cyprolet ndi bronchitis

Mu milandu yomwe chifukwa cha bronchitis ndimatenda oyambitsidwa ndi bakiteriya, ndiye kuti, chifukwa cha kuperekedwa kwa mankhwala opha maantibayotiki. Pamene mafinya akuwonekera m'matumbo a sponum kapena ma bronchitis pafupipafupi. Ubwino pano umaperekedwa pamapiritsi.

Ciprolet imathandizira bwino magawo a bronchitis kapena mankhwala ena akapanda ntchito. Njira ya mankhwala ndi mlingo umayesedwa pambuyo pakuwunika ndi kukambirana ndi dokotala. Nthawi zambiri, makonzedwe a Ciprolet samatha masiku 10, piritsi limodzi katatu patsiku.

Ndi angina

M'mikhalidwe yowopsa ya purulent tonillitis ndi chifuwa kwa ma antibacterial ena, mapiritsi a Ciprolet ndi omwe amapangidwa, omwe amawapangitsa kuti akhale ofunikira pakuchiza matenda. Nthawi zambiri, mu mawonekedwe owopsa a angina, mankhwala othandizira a penicillin ndi macrolide angapo alibe mphamvu.

Woopsa angina, Ciprolet imagwiritsidwa ntchito ngati njira yothetsera kulowetsedwa.

Mlingo wovomerezeka wa mapiritsi a munthu wamkulu pa matenda a tonsillitis ndi theka la piritsi 2-3 patsiku. Tengani mankhwalawa kuchokera masiku 7 mpaka 10.

Kwa mitundu yayikulu, mapiritsi 1-1.5 amalembedwa katatu, komanso masiku 7-10. Zizindikiro zikayamba kugwira ntchito, mankhwalawa amapitilizidwa kumwa kwa masiku ena atatu. Kwa purulent tonillitis, mankhwalawa amadziwitsidwa pa mlingo umodzi pakadutsa masabata 3-4, pofuna kupewa zovuta.

Mankhwala Ciprolet ndi sinusitis

Cyprolet yokhala ndi sinusitis imagwiritsidwa ntchito ngati matenda a bakiteriya aphatikizika nawo. Mankhwalawa ali ndi zotsatirapo zoyipa, pomwe zimagwiritsidwa ntchito ngati chithandizo ndi mankhwala ena sichinathandize.

Akuluakulu amakulimbikitsidwa kumwa piritsi limodzi la Ciprolet 2 kawiri pa tsiku kwa masiku 5-7, malingana ndi kuopsa kwa matendawa.

Cyprolet mu gynecology ya cystitis mwa akazi

Cyprolet imatha kutengedwa nthawi iliyonse komanso cystitis iliyonse. Mlingo wofotokozedwa ndi dokotala potengera zomwe wodwalayo adziwa - zaka, kulemera kwake, komanso kuuma kwa matendawa ndi kupezeka kwa matenda oyamba.

Mlingo woyenera wochizira cystitis mwa azimayi ndi mapiritsi awiri patsiku ndikupumula kwa maola 12. Maphunzirowa amatenga masiku 5 mpaka 14. Akatswiri amalimbikitsa azimayi omwe ali ndi vuto la impso kuti achepetse kuchuluka kwa mankhwalawa nthawi ziwiri.

Ndi prostatitis

Mu mawonekedwe owopsa a prostatitis, makonzedwe a mankhwala a Ciprolet amadziwika ndi njira yokonzanso pakamwa, itadutsa gawo lokhululuka, mapiritsi amawayikidwa. Kusinthana ndi mtundu wamakonzedwe a makonzedwe ndikotheka patsiku la 4 la jakisoni.

Mlingo woyenera wa amuna omwe ali ndi prostatitis ndi 500 mg maola 12 aliwonse. Kulandila kumatenga masiku 10, atha kuwonjezeredwa mwakufuna kwa dokotala. Ndizofunikanso kudziwa kuti pamaso pa kukanika kwa aimpso kapena chiwindi, mlingo wa Ciprolet uyenera kuchepetsedwa 2 times.

Cyprolet kwa ana: malangizo ogwiritsira ntchito

Maantibayotiki saloledwa kwa ana munthawi yakukula kufikira zaka 18.

Ngati chithunzi cha matenda ndichovuta, ndiye kuti mankhwalawa ndi mankhwala opatsirana amaloledwa kuyang'aniridwa kuyambira ali ndi zaka 15, pamene muyezo wowerengera ndi kusinthidwa payekhapayekha.

Mlingo wovomerezeka kuti uchotse zovuta zomwe zimayambitsidwa ndi Pseudomonas aeruginosa wa ana omwe ali ndi muscid pulmonary fibrosis wazaka zapakati pa 5 mpaka 17 ndi 20 mg pa kilogalamu imodzi ya kulemera kwa maola 12 aliwonse (mlingo waukulu wa tsiku lililonse wa mwana sayenera kupitirira 1500 mg). Maphunzirowa amatenga masiku 10 mpaka 14.

Kuti muthane ndi kupewa matenda a anthrax mu mawonekedwe am'mapapo mwanga, muyenera kumwa 15 mg pa kilogalamu imodzi ya kulemera kwa thupi maola 12 aliwonse. Mlingo waukulu kwambiri pa mwana sayenera kupitirira 500 mg, ndipo tsiku lililonse sayenera kupitirira 1000 mg. Maphunzirowa amatenga masiku 60.

Zotsatira zoyipa

Zotsatira zoyipa pamene mukumwa mankhwalawa zimatha kuonedwa kuchokera mbali:

ChimbudziMachitidwe amanjenjeZolingalira za kuzindikiraMtima wamtimaMa hememopoietic machitidweZizindikiro zasayansiNjira yamikodzoThupi lawo siligwirizanaDongosolo laumiseche
1nseruchizungulirekumva kuwonongekakutsitsa magazikuchepa magazihyperglycemiakusungika kwamikodzokuyabwanyamakazi
2kutsegula m'mimbamututinnitustachycardiathrombocytopeniahypoprothrombinemiapolyuriaurticariazingwe za tendon
3kusanzakutopakuwonongeka kwamawonekedwekuthamanga kwa magazi pakhungu la nkhopeleukopeniahypercreatininemiadysuriakutulutsa magazimyalgia
4kupweteka kwam'mimbankhawakulakwirakutentha kwa mtimagranulocytopeniahyperbilirubenimiaalbinuriamankhwalawatenosynovitis
5chisangalalokusowa tulozosokonezaleukocytosiskutulutsa magazi urethralpetechiae (malo otupa)arthralgia
6kukomokakunjenjemerathrombocytosishematuriakutupa kwa nkhope, larynxnyamakazi
7chiwindizolotautachepa wa nayitrogeni wa impsokupuma movutikira
8hepatonecrosisKuzindikira kwa zopwetekakhalidzithunzi
9jaundicethukutaeosinophilia
10kuchuluka kwachuma kwachumavasculitis
11kukhumudwaerythema (nodular, exudative multiform, exacative exudative (Stevens-Johnson syndrome)),

12kuyerekezeraMatenda a Lyell.

13migraines
14kukomoka

Kuphatikiza apo, kupezeka kwa kufooka kwapafupipafupi ndikuwonekeraku ndikotheka - candidiasis ndi pseudomembranous colitis.

Kodi ndingathe kutenga Cyprolet pa nthawi yapakati?

Mankhwala opha mabakiteriya a Ciprolet amatanthauza mankhwala ambiri omwe amaletsedwa mosamala panthawi yoyembekezera komanso panthawi yoyamwitsa. Ciprolet sinayesedwe mwa amayi apakati, kotero momwe zimayambira mwana wosabadwa sanaphunzire. Mayeso anali kuchitidwa pa nyama zokha.

Cyprolet ndi mowa - kuyanjana: ndizotheka kumwa

Mukamayanjana ndi mowa, kaphatikizidwe ka michere ya chiwindi yomwe imapanga ma ethanol ndi zinthu zake zowola zimayima.

Kenako Zizindikiro za kuledzera zimakulirakulira komanso nthawi yake, poizoni woopsa umachitika. Madigiri awo amakhudzidwa ndi kuchuluka kwa mowa womwe umamwetsa komanso momwe munthu akuonekera m'thupi.

Kuchita ndi mankhwala ena

  • mukamagwiritsa ntchito mankhwala omwe amakhudza madzi a asidi m'matumbo (maantacid), mankhwala okhala ndi aluminium hydroxide, magnesium, mchere wamchere, chitsulo ndi zinc zingathandize kuchepetsa kuyamwa kwa ciprofloxacin ndi thupi, kotero muyenera kuyang'anira nthawi yopuma kuchokera maola 1 mpaka 4 pakati pawo ,
  • mukamalandira theophylline, muyenera kuwunika momwe amaunika, chifukwa imatha kutuluka mwamphamvu m'madzi a m'magazi,
  • Mukamamwa ndi cyclosporine, nthawi zina, kuchuluka kwa ma serum creatinine kumawonjezeka,
  • Mukamamwa ndi warfarin, mphamvu za ciprofloxacin zimatheka nthawi zina,
  • pa milingo yayikulu ya quinols ndi mankhwala ena osapatsa-non-steroid, kupwetekedwa kunadziwika,
  • Mankhwala akhoza kuphatikizidwa pa mankhwala azlocillin, ceftazidime, meslocillin, azlocillin, azoxazoylpenicillins, vancomycin, metronidazole, clindamycin.

Mlingo ndi makonzedwe

Mapiritsi amayenera kumwedwa pakamwa (mkati), mosasamala chakudya, ndi madzi pang'ono. Mapiritsiwo ayenera kumezedwa lonse osafuna kutafuna. Mukamamwa Ciprolet pamimba yopanda kanthu, imakamizidwa mwachangu, ndipo simuyenera kumwa mankhwalawa ndi mkaka kapena zakumwa zomangidwa ndi calcium. Kashiamu yokhala ndi zakudya sizikhudzana ndi mayamwa.

  • matenda opatsirana thirakiti: 500-700 mg 2 pa tsiku,
  • matenda a genitourinary dongosolo: pachimake, osavuta - 250-500 mg 2 kawiri pa tsiku, cystitis mwa azimayi osaneneka - 500 mg 1 nthawi, zovuta - 500-750 mg 2 kawiri pa tsiku, matenda amtundu wa m'mimba (kupatula gonorrhea) - 500 -750 mg 2 pa tsiku, chinzonono - 500 mg 1 kamodzi patsiku, kutsekula m'mimba - 500 mg kawiri pa tsiku,
  • matenda ena: 500 mg 2 kawiri pa tsiku,
  • matenda oopsa oopsa oopsa kwambiri (kuphatikiza pa streptococcal chibayo, matenda am'mafupa ndi mafupa, septicemia, peritonitis): 750 mg kawiri pa tsiku.

Malangizo a dosing oyenera a magulu apadera odwala:

  • odwala azaka zopitilira 65: mlingo uyenera kuchepetsedwa malingana ndi kuopsa kwa matendawo ndi chilolezo cha creatinine,
  • Kulephera kwa impso: ndi chilolezo cha creatinine kuyambira 30 mpaka 60 ml / mphindi, mlingo waukulu wa ciprofloxacin ndi 1000 mg / tsiku, ndi kuvomerezeka kwa creatinine pansi pa 30 ml / mphindi - 500 mg / tsiku, ngati wodwalayo ali ndi hemodialysis, Ciprolet iyenera kutengedwa pambuyo pake. Pazamalonda omwe akupitilira peritoneal dialysis, mankhwala okwanira tsiku lililonse ndi 500 mg.
  • chiwindi kulephera: kusintha kwa mankhwalawa sikofunikira.

Kutalika kwa chithandizo kumatengera kuopsa kwa matendawa, kuwongolera ndi kuwongolera kwa matenda. Zizindikiro zikazimiririka, makonzedwe ake a mankhwalawa amayenera kupitilizidwa kwa masiku osachepera atatu. Kutalika kwakanthawi kachipatala:

  • gonorrhea wovuta, cystitis: 1 tsiku,
  • matenda a impso, kwamikodzo thirakiti, matenda amkati: mpaka masiku 7,
  • neutropenia odwala immunocompromised: nthawi yonseyo,
  • osteomyelitis: zosaposa miyezi 2,
  • matenda ena: masiku 7-14,
  • matenda oyambitsidwa ndi Streptococcusspp. ndi Chlamydiaspp: osachepera masiku 10.

Pofuna kupewa komanso kuchiza matenda a m'mapapo a anthrax: 500 mg 2 pa tsiku kwa masiku 60. Pamafunika kuyamba kumwa mankhwalawo mutangotenga kachilombo (mukumaganizira kapena kutsimikiziridwa).

Ana ndi achinyamata

Malangizo omwe ali pompopompo akulimbikitsidwa (pokhapokha akuwonetsa):

  • mankhwala a mavuto a Pseudomonas aeruginosa ana 5-5 zaka ndi m`mapapo mwanga cystic fibrosis: 20 mg / kg thupi kawiri pa tsiku (pazipita tsiku lililonse - 1500 mg). Kutalika kwa mankhwalawa ndi masiku 10 mpaka 14,
  • kupewa ndi kuchiza anthrax ya pulmonary (Bacillus anthracis): 15 mg / kg thupi kawiri pa tsiku. Mlingo wambiri watsiku ndi tsiku ndi 1000 mg. Kutalika kwa mankhwalawa ndi masiku 60.

Kuphatikiza kwa kulowetsedwa

Zomwe zimachitika mmalo ndizotheka: ndi kutalika kwa kulowetsedwa kosakwana mphindi 30, edema imakhala yofala kwambiri (yotupa pakhungu). Izi zimachitika lokha kutha kwa kulowetsedwa ndipo sikuti kuphwanya kugwiritsa ntchito mankhwalawa (ngati njira yake ilibe zovuta).

M'pofunika kuganizira zomwe zili ndi sodium mankhwala enaake mu yankho la odwala omwe ali ndi zochepa za sodium.

Zowonjezera za mapiritsi

Kuphatikiza kosakanikirana ndi kukonzekera kwa cationic, mchere wowonjezera womwe umakhala ndi chitsulo, calcium, magnesium, sucralfate, maantacid, polymer phosphate, aluminium, komanso kukonzekera ndi gawo lalikulu la buffer lomwe lili ndi magnesium, calcium, aluminium, kumachepetsa kuyamwa kwa ciprofloxacin. Pankhaniyi, tikulimbikitsidwa kuti muzimwa kamodzi kapena maola 4 mutatha kumwa mankhwalawa. Kuletsa kumeneku sikugwira ntchito kwa gulu la H2-histamine receptor blockers.

Zopangira mkaka ndi zakumwa zolemera ndi mchere siziyenera kutengedwa nthawi yomweyo ndi Ciprolet, chifukwa zimatha kuchepetsa kuyamwa kwa ciprofloxacin.

Tsifran kapena Tsiprolet: zomwe zili bwino

Tsifran ndi analog ya Tsiprolet. Imagwiranso ntchito polimbana ndi gramu yabwino komanso gram negative; fungi, ma virus, tizilombo toyambitsa matenda a syphilis ndi zina za anaerobic sizigwirizana nayo.

Mankhwalawa onse ali ndi zofanana komanso zotsutsana.Mosiyana ndi Cifran, Ciprolet amalumikizana bwino ndi mankhwala ena.

Tsipromed kapena Tsiprolet: zomwe zili bwino

Tsipromed ndi analog ina ya Tsiprolet, mu kapangidwe kake kameneka kamagwiritsidwe ntchito. Mankhwalawa 2 amasiyana pamtengo - ngati madontho a Ciprolet ndi ma ruble 50-60 mu mankhwala, ndiye Cipromed pafupifupi rubles 100-140. Cypromed imapezeka mu mawonekedwe a makutu amaso ndi amaso.

Mankhwala a Ciprolet omwe ali m'mapiritsi amagwira ntchito pochiza matenda osiyanasiyana ndi zotupa zama bakiteriya, zomwe zimagwiritsidwa ntchito mosamala mankhwala. Mtengo wotsika komanso kupezeka kwakukulu, posankha mankhwala othandizira, amakupatsani mwayi woti mumusankhire.

Kusiya Ndemanga Yanu