Mapiritsi a Actovegin: malangizo ogwiritsira ntchito

Mankhwalawa amapezeka mu mawonekedwe a mapiritsi, ophimbidwa ndi chipolopolo chachikasu. Ali ndi mawonekedwe ozungulira, owala.

Mankhwala amapangidwanso m'njira yothetsera jakisoni wa 40 mg / ml, 20% gel osakaniza kuti azigwiritsa ntchito kunja, 5% kirimu ndi mafuta ogwiritsa ntchito kunja.

Piritsi limodzi lili ndi 200 mg ya ng'ombe yotsitsidwa ndi hemoderivative. Omwe amapezekapo ndi monga: cellulose, magnesium stearate, talc ndi povidone K90.

Kuphatikizika kwa chipolalachi kumaphatikizapo: macrogol 6000, wax glycol wax, acacia chingamu, titanium dioxide, povidone K30, diethyl phthalate, sucrose, hypromellose phthalate, talc, utoto wa quinoline, chikasu cha aluminium.

Mlingo

200 mg mapiritsi okhala ndi mafilimu

Ckusiya

Piritsi imodzi yokhala ndi:

ntchito: ng'ombe yotsika hemoderivative - 200,00 mg

zokopa: cellcose ya microcrystalline, povidone - (K 90), magnesium stearate, talc

kapangidwe ka chipolopolo: sucrose, titanium dioxide (E 171), utoto wa zotayidwa wachikasu aluminiyamu (E 104), glycol sera, povidone (K-30), macrogol-6000, gamu ya acac, hypromellose phthalate, diethyl phthalate, talc

Mapiritsi ozungulira a biconvex, ovala utoto wamafuta achikasu, onyezimira

Mankhwala

Pa mulingo wa maselo, mankhwalawa amathandizira kugwiritsidwa ntchito kwa glucose ndi oksijeni, komwe, kumapangitsa kuwonjezeka kwa metabolism. Mphamvu yonse ya njirazi imakuthandizani kuti mulimbikitse mphamvu ya khungu, makamaka ndi zotupa za ischemic ndi hypoxia.

Zokhudza mphamvu ya Actovegin pathupi ndizofunika kwambiri pochiza matenda ashuga a polyneuropathy.

Odwala omwe ali ndi matenda ashuga a polyneuropathy (paresthesias, ululu wosokonekera, kuchuluka kwa malekezero ena) komanso odwala matenda ashuga amatsika ndikuchepa kwa zovuta zakukhudzana ndi kusinthika kwa thanzi la m'maganizo panthawi ya njira zochizira.

Popeza Actovegin imakhala ndi zofunikira zathupi, ndizosatheka kuphunzira zamachitidwe ake a pharmacokinetic mpaka kumapeto.

Zizindikiro zogwiritsidwa ntchito

Mankhwala tikulimbikitsidwa kuti mugwiritse ntchito pamavuto monga awa:

Dongosolo la matenda ashuga a polyneuropathy,
Zotsalira zotsalira za hemorrhagic stroke,
Encephalopathies a magwero osiyanasiyana,
Ischemic stroke
Kuvulala kwam'mutu
Chepetsa zilonda 1-3 madigiri,
Radiation neuropathy ndi ma radiation osiyanasiyana ovulala pakhungu,
Angiopathy
Zilonda zam'mimba, bedores, zovuta zamatumbo,
Kulephera kwa kusinthika,
Kuwonongeka kwa zotumphukira venous kapena ochepa magazi.

Njira yogwiritsira ntchito

Mapiritsi akulimbikitsidwa kuti adye musanadye, simuyenera kutafuna, muyenera kumwa madzi ambiri. Mlingo woyenera kumwa ndi mapiritsi 1-2 katatu patsiku. Njira ya mankhwalawa imachokera ku milungu 4 mpaka 6.

Mlingo woyamba wa matenda ashuga polyneuropathy ndi 2 g / tsiku kwa mtsempha wa magazi kwa masabata atatu. Pambuyo pake, mutha kusinthira pamapiritsi pogwiritsa ntchito zidutswa 2-3 patsiku, pafupifupi miyezi 4-5.

Ndi makolo makonzedwe, chitukuko cha ziwengo ndizotheka, pachifukwa ichi ndikoyenera kupereka zofunikira zoyenerera zothandizira odwala mwadzidzidzi.

Zosaposa 5 ml zimayendetsedwa kudzera m'mitsempha, zomwe zimayambitsa kupezeka kwa hypertonic katundu wa mankhwala.

Chithandizo cha gel chikuchitika chifukwa cha kuvulala kwa radiation, kupsa, zilonda. Amayikidwa timitu komanso yokutidwa ndi compress. Kavalidwe kamasinthidwa kamodzi pa sabata.

Kirimuyi imagwiritsidwa ntchito pochiritsa mabala amvula. Itha kugwiritsidwa ntchito pamaso pa zilonda za kukakamiza.

Kugwiritsa ntchito zonona, mafuta ndi thupi kumathandiza kuti khungu lizipanganso msanga, zomwe zimapangitsa kuti mabala azizizira komanso kutentha.

Pochiza maso, dontho limodzi la 1 la gel osakaniza limagwiritsidwa ntchito pakhungu lomwe limakhudzidwa katatu patsiku.

Zotsatira zoyipa

Mwa zina zoyipa kuchokera kugwiritsidwa ntchito tingaone:

Kutupa,
Kupumira mwachangu
Kuchepetsa mseru
Zowawa
Paresthesia
Anaphylactic mantha,
Acrocyanosis,
Zofooka
Kutsegula m'mimba
Mutu
Kukongola kwa khungu
Zowawa
Urticaria,
Kutentha
Hyperemia wa pakhungu,
Matenda oopsa
Ululu m'dera lumbar,
Mphumu
Kutentha kwamphamvu
Ma syndromes opweteka m'dera la epigastric,
Kuchulukitsa thukuta.

Ngati chimodzi mwazizindikiro zomwe tatchulazi zikuchitika, ndikofunikira kusiya kugwiritsa ntchito Actovegin ndipo nthawi yomweyo funsani katswiri.

Malangizo apadera

Ndi mawonetseredwe osiyanasiyana owonetsa thupi, ndikofunikira kusiya kumwa mankhwalawo. Pankhaniyi, symptomatic therapy (kugwiritsa ntchito GCS kapena antihistamines) imachitika.

Khalidwe la kafukufuku woyeserera likuwonetsa kuti ngakhale muyezo 30-30 kuchulukirapo kuposa momwe umalimbikitsidwira sizimayambitsa zovuta komanso zoyipa.

Popeza kuwonetsedwa kwa anaphylactic zimachitika, jakisoni wofunikira ndiyofunikira musanagwiritse ntchito. Ndi makonzedwe a mu mnofu, mankhwalawa amayenera kuperekedwa pang'onopang'ono.

Njira yapamwamba yothetsera makonzedwe amkati imakhala ndi chikasu chachikuda, chokhala ndi utoto wosiyana sioyenera kubayidwa, kuti mupewe zotsatira zoyipa.

Ngati mukuwongolera kangapo, ndikofunikira kuwongolera momwe magetsi amayendera.

Mbovu otseguka sangasungidwe, koma ayenera kutayidwa nthawi yomweyo.

Limagwirira ntchito Actovegin

Actovegin ndi mankhwala achilengedwe achilengedwe omwe amapezeka kudzera mu dialysis ndi kupatsidwa kwa magazi a ng'ombe ya ng'ombe. Ili ndi zotsatirazi:

Zabwino pa mayendedwe a shuga ndi kugwiritsa ntchito,
Imayambitsa kumwa kwa oxygen,
Imakhazikika m'mimba mwa ma plasma a maselo omwe ali ndi ischemia,
Amachepetsa mapangidwe a lactate.

Mphamvu ya antihypoxic ya Actovegin imayamba kuwonekera patatha mphindi 30 mutatenga mapiritsiwo mkati ndikufika pazowonjezera pambuyo pa maola 2-6. Actovegin imachulukitsa kuchuluka kwa phosphocreatine, adenosine diphosphate, adenosine triphosphate, komanso amino acid asipate, glutamate ndi gamma-aminobutyric acid.

Chifukwa chiyani malangizo mapiritsi a Actovegin

Madokotala pachipatala cha Yusupov amapereka mankhwala a Actovegin 200mg pochizira matenda otsatirawa:

Vuto la kuchepa kwa mtima ndi kagayidwe kachakudya ka bongo (mitundu yosiyanasiyana ya kusowa kwa cerebrovascular, dementia, kuvulala kwamtundu wamatumbo),
Zovuta zam'mimba komanso zotupa zam'mimba, komanso zotsatira zake (angiopathies, trophic zilonda),
Matenda a shuga

Contraindication pakutenga mapiritsi a Actovegin ndichidziwitso chowonjezeka cha ntchito yogwira ntchito komanso ngati zigawo zothandiza. Gwiritsani ntchito mosamala matenda otsatirawa:

Kulephera kwamtima II ndi digiri ya III,
Pulmonary edema
Oliguria, anuria,
Hyperhydrate (kudzikundikira kwa madzimadzi m'thupi).

Popereka mankhwala a Actovegin pa nthawi yoyembekezera komanso mkaka wa m'mawere, madokotala pachipatala cha Yusupov amaganizira kuchuluka kwa mapindu ndi vuto lomwe lingachitike chifukwa chogwiritsa ntchito mankhwalawa.

Momwe mungatenge mapiritsi a Actovegin

Momwe mungamwere Actovegin? Actovegin 200 mg amatengedwa mapiritsi awiri katatu pa tsiku musanadye, osafuna kutafuna, ndimadzi ochepa. Kutalika kwa mankhwalawa kuyambira 4 mpaka 6 milungu.

Mukamamwa mapiritsi a Actovegin, zimachitika zovuta zina:

Urticaria,
Edincke's edema,
Mankhwala osokoneza bongo.

Zikatero, chithandizo ndi mapiritsi a Actovegin amayimitsidwa. Ngati zikuwonetsa, madokotala amathandizira poyerekeza ndi antihistamines kapena mahomoni a corticosteroid.

Mitundu ya kumasulidwa ndi alumali moyo wa Actovegin

Mapiritsi a Actovegin 200 mg amaikidwa mu mabotolo amdima amdima ali ndi khosi laling'ono komanso choluka, chomwe chimayang'anira kutsegulidwa koyamba. Botolo 1 yokhala ndi malangizo ogwiritsira ntchito Actovegin imayikidwa mkatoni.

Pankhani yoyika ma CD a mankhwala a Sotex Farmfirema CJSC, 10, 30, kapena 50 amaikidwa m'mabotolo a galasi la bulauni a hydrolytic class ISO 720-HGA 3 okhala ndi khosi lotsekeka, losindikizidwa ndi zotengera za aluminium ndikutulutsa koyambira koyambirira ndikumata magesi. Botolo imodzi ya Actovegin yokhala ndi malangizo ogwiritsira ntchito amaikidwa pakatoni.

Alumali moyo wa mapiritsi a Actovegin 200 mg 3 zaka. Mankhwalawa sagwiritsidwa ntchito pambuyo pa nthawi ino. Mapiritsi a Actovegin amayenera kusungidwa kutentha osapitirira 25 ° C pamalo amdima. Mankhwala amaperekedwa ku pharmacies mwa mankhwala.

Bongo

Palibe deta pa kuthekera kwa bongo wa Actovegin®. Kutengera ndi data ya pharmacological, palibe zovuta zina zomwe zimayembekezera.

Kutulutsa Fomundi kunyamula

Mapiritsi 50 amaikidwa mumbale zamagalasi amdima, otsekedwa ndi ma lids, okhala ndi oyang'anira oyamba oyamba. Kwa botolo limodzi, limodzi ndi malangizo ogwiritsira ntchito zachipatala m'boma ndi zilankhulo zaku Russia, ikani paketi.

Zolemba zoteteza kuzungulira zowonekera ndi zolemba za holographic ndi chiwongolero choyamba chotsegulidwa zimapakidwa pa paketi.

Wopanga

Takeda Austria GmbH, Austria

Dzinalo ndi dziko laomwe amalembetsa satifiketi

LLC Takeda Mankhwala, Russia

Adilesi ya bungweli yomwe imavomereza zodula kuchokera kwa ogula pamsika wazogulitsa (katundu) ku Republic of Kazakhstan

Ofesi yoyimira a Takeda Osteuropa Holding GmbH (Austria) ku Kazakhstan

Kutulutsa mafomu ndi kapangidwe kake

Actovegin ikupezeka mu mtundu wa yankho la jakisoni komanso mwanjira ya mapiritsi.

Pamwamba pa mapiritsi mulinso filimu ya enteric ya utoto wonyezimira, wokhala ndi:

chingamu
sucrose
povidone
titanium dioxide
phiri njuchi glycol sera,
talcum ufa
macrogol 6000,
hypromellose phthalate ndi dibasic ethyl phthalate.

Utoto wachikasu wa Quinoline ndi varnish wa aluminiyamu umapereka mfuti inayake ndikuwala. Piritsi yayikulu imakhala ndi 200 mg ya yogwira popanga magazi a ng'ombe, komanso microcrystalline cellulose, talc, magnesium stearate ndi povidone ngati mankhwala ena owonjezera. Magawo a mankhwalawo ali ndi mawonekedwe ozungulira.

Imodzi mwazomwe akutulutsa Actovegin ndi mapiritsi.

Yankho limakhala ndi 5 ml galasi ampoules, omwe ali ndi 200 mg yogwira ntchito - Actovegin concentrate, yopangidwa kuchokera ku magazi hemoderivative a ng'ombe, omasulidwa ku protein. Madzi osalala a jakisoni amakhala ngati chowonjezera chowonjezera.

Zotsatira za pharmacological

Actovegin ndi njira yolepheretsa kukula kwa hypoxia. Kupanga mankhwalawa kumakhala mu dialysis yamagazi am ng'ombe ndikulandira hemoderivat. Zinthu zopanda pake pazopanga zimapanga zovuta ndi mamolekyu wolemera mpaka 5000 dalton. Chithandizo choterechi ndi antihypoxant ndipo chimakhala ndi zotsatira zitatu mthupi:

kagayidwe
bwino masinthidwe am'manja,
neuroprotective.

Kugwiritsa ntchito mankhwalawa kumakhudza mayendedwe ndi shuga ya shuga chifukwa cha phosphoric cyclohexane oligosaccharides, omwe ali gawo la Actovegin. Kuthamangitsa kugwiritsidwa ntchito kwa glucose kumathandizira kusintha kwa mitochondrial ntchito zama cell, kumabweretsa kuchepa kwa kaphatikizidwe ka lactic acid kumbuyo kwa ischemia ndikuwonjezera mphamvu kagayidwe.

Actovegin ndi njira yolepheretsa kukula kwa hypoxia.

Mphamvu ya neuroprotective ya mankhwalawa imachitika chifukwa cha kulepheretsa kwa apoptosis ya maselo a mitsempha pamavuto. Kuchepetsa chiopsezo cha kufa kwa minyewa, mankhwalawa amachepetsa zochitika za beta-amyloid ndi kappa-bi, ndikuwonetsa apoptosis ndikuwongolera njira yotupa m'mitsempha ya zotumphukira zamkati.

Mankhwala amakhudza endothelium wa capillary chotengera, sinamizidwe kayendedwe kazachilengedwe mu minofu.

Zotsatira zamaphunziro a zamankhwala, akatswiri sanathe kudziwa nthawi yomwe angafike nthawi yayitali yogwira ntchito m'magazi am'magazi, theka la moyo ndi njira yodutsa. Ichi ndi chifukwa kapangidwe ka hemoderivative. Popeza chinthucho chimangokhala ndi zofunikira zathupi zokha zomwe zimapezeka mthupi, sizingatheke kudziwa magawo enieni a pharmacokinetic. The achire zotsatira zimawonekera theka la ola pambuyo pakamwa makonzedwe ndikufika pazenera pambuyo maola 2-6, kutengera mawonekedwe a wodwalayo.

Pochita malonda ogulitsa, sipanakhalepo zochitika zakuchepa kwa mankhwalawa kwa odwala omwe ali ndi vuto la impso.

Pochita malonda ogulitsa, sipanakhalepo zochitika zakuchepa kwa mankhwalawa kwa odwala omwe ali ndi impso kapena hepatic.

Contraindication

Mankhwalawa amadziwikiridwa kwa anthu omwe ali ndi chiwopsezo chowonjezereka cha zinthu za Actovegin ndi mankhwala ena a metabolic. Ndikofunikira kukumbukira za sucrose pagulu lakunja la mapiritsi, zomwe zimalepheretsa kayendedwe ka Actovegin kwa anthu omwe ali ndi vuto la glucose-galactose mayamwidwe kapena chibadwa chokhala ndi tsankho. Mankhwala osavomerezeka chifukwa cha kuchepa kwa sucrose ndi isomaltase.

M'pofunika kuwongolera mkhalidwe wamasamba a mtima kwa anthu omwe ali ndi vuto la mtima la 2 kapena 3. Chenjezo liyenera kugwiritsidwa ntchito ngati mapapo a edema, anuria ndi oliguria atupa. Zotsatira zochizira zitha kuchepa ndi kuchepa thupi.

M'pofunika kuwongolera mkhalidwe wamasamba a mtima kwa anthu omwe ali ndi vuto la mtima la 2 kapena 3.

Momwe mungatenge Actovegin 200

Mapiritsi amatengedwa pakamwa musanadye. Osatafuna mankhwalawa. Mlingo umakhazikitsidwa kutengera mtundu wa matenda.

Pankhani ya matenda ashuga polyneuropathy, kulowetsedwa kwa mtsempha tsiku lililonse 2000 mg tikulimbikitsidwa. Pambuyo pa 20 omwe adangotsika, kusintha kwa pakamwa pa fomu ya Actovegin ndikofunikira. 1800 mg pa tsiku zotchulidwa ndi pafupipafupi makonzedwe 3 pa tsiku 3 mapiritsi. Kutalika kwa mankhwalawa kumasiyana kuyambira miyezi inayi mpaka isanu.

Pankhani ya matenda ashuga polyneuropathy, kulowetsedwa kwa mtsempha tsiku lililonse 2000 mg tikulimbikitsidwa.

Zotsatira zoyipa

Zotsatira zoyipa za mankhwalawa zimatha kuchitika chifukwa cha mlingo wosankhidwa mosayenera kapena kugwiritsa ntchito molakwika mankhwalawo.

Wothandizila kagayidwe kachakudya amatha kusokoneza mwachindunji kagayidwe ka calcium, chifukwa cha momwe mayamwidwe a calcium ioni amasokonezeka. Mwa odwala odziwikiratu, chiopsezo chokhala ndi gout chimawonjezeka. Nthawi zina, mawonekedwe a kufooka kwa minofu ndi kupweteka.

Mankhwalawa akapaka jekeseni wa minofu kapena mu ulnar mtsempha, redness, phlebitis (kokha ndi kulowetsedwa kwa iv), zilonda zam'mimba komanso zotupa m'malo omwe jekeseni anaikapo zimatha. Ndi chidwi chochulukirapo ku Actovegin, urticaria imawoneka.

Mukatenga metabolic othandizira, kuyankha kwa chitetezo cha mthupi ndi kuchuluka kwa leukocytes mthupi ndi kugonjetsedwa ndi matenda opatsirana kumatha kuchepa.

Odwala omwe ali ndi minofu hypersensitivity, dermatitis ndi fever fever amatha. Nthawi zina, angioedema ndi anaphylactic angachitike.

Kuchita ndi mankhwala ena

Mothandizidwa ndi mtsempha wa Mildronate ndi Actovegin, ndikofunikira kuyang'ana pakadutsamo pakati pa jakisoni wa maola angapo, chifukwa sikunenedwe ngati mankhwalawa amalumikizana.

Wothandizila kagayidwe amayenda bwino ndi Curantil ya gestosis (capillary vascular vuto) mwa amayi apakati omwe ali ndi chiopsezo chobadwa isanakwane.

Pogwiritsa ntchito mofananamo Actovegin ndi ACE inhibitors (Captopril, Lisinopril), tikulimbikitsidwa kuwunika momwe wodwalayo alili. An blockoter ya eniotensin-yotembenuza enzyme imayikidwa limodzi ndi metabolic wothandizira kuti magazi azithamanga mu ischemic myocardium.

Chenjezo liyenera kuchitika pakukhazikitsidwa kwa Actovegin ndi potaziyamu wotsekemera wopatsa mphamvu.

M'malo mankhwalawa pokhapokha achire zotsatira zake zingakhale mankhwala omwe ali ndi mankhwala omwewo:

Vero-Trimetazidine,
Cortexin
Cerebrolysin
Solcoseryl.

Mankhwalawa ndi otsika mtengo pamtengo wamtengo.

Malo opumulira Actovegin 200 kuchokera ku pharmacy

Mankhwalawo sagulitsidwa popanda kulandira mankhwala.

Mankhwalawa amangoikidwa pazifukwa zachuma mwachindunji, chifukwa sizingatheke kudziwa zotsatira za Actovegin pa munthu wathanzi.

Mtengo wamankhwala ku Russia umasiyana ndi ma 627 mpaka 1525 rubles. Ku Ukraine, mankhwalawa amalipira pafupifupi 365 UAH.

Ndemanga za madotolo ndi odwala pa Actovegin 200

Mikhail Birin, Neurologist, Vladivostok

Mankhwalawa sanatchulidwe ngati monotherapy, chifukwa chake zimakhala zovuta kulankhula za ogwira mtima. Chomwe chimagwiritsidwa ntchito ndi hemoderivative, chifukwa chake ndikofunikira kuyang'ana momwe wodwalayo alili: sizikudziwika bwino momwe mankhwalawa adayeretsedwa panthawi yopanga, zomwe zingachitike chifukwa chogwiritsa ntchito. Odwala amalola mankhwalawa bwino, koma ndimakonda kudalira zopangidwa. Nthawi zina, mutu umayamba.

Alexandra Malinovka, wazaka 34, Irkutsk

Abambo anga anaulula thrombophlebitis m'miyendo. Gangrene adayamba, ndipo mwendo udadulidwa. Zinthu zinali zovuta ndi matenda a shuga: matendawa ankachira mosavuta ndipo amatha kupindika kwa miyezi 6. Adafunsidwa kuti akathandizike kuchipatala, komwe Actovegin adathandizira kudzera m'mitsempha. Zinthu zinayamba kuyenda bwino. Atatulutsa, abambo adatenga mapiritsi a Actovegin ndi jakisoni a 5 ml mwamphamvu malinga ndi malangizo ogwiritsa ntchito. Chilondacho pang'onopang'ono chidachira kwa mwezi umodzi. Ngakhale mtengo wokwera, ndikuganiza kuti mankhwalawa ndi othandiza.