Diabeteson analogues

Diabeteson MV (mapiritsi) Kutalika: 47

Kukonzekera piritsi ku Russia kuchiza matenda a shuga. The yogwira pophika gliclazide mu 60 mg piritsi. Amawonetsedwa pochiza matenda amishuga amtundu wa 2 komanso chifukwa cha prophylactic.

Mndandanda wa mankhwala Diabeteson MV

Analogue ndiotsika mtengo kuchokera ku ma ruble 160.

Gliclazide MV ndi piritsi lokonzekera mankhwalawa mtundu wa matenda a shuga 2 chifukwa cha zomwe zimagwiritsidwa ntchito mu 30 mg. Amawerengedwa kuti asamadye zakudya zolimbitsa thupi komanso azilimbitsa thupi. Gliclazide MV imapikisidwa kwa odwala omwe ali ndi matenda a shuga 1 (omwe amadalira insulin).

Analogue ndiyotsika mtengo kuchokera ku ma ruble 168.

Glidiab ndi amodzi mwamalo opindulitsa kwambiri a gliclazide. Imapezekanso m'mapiritsi, koma mulingo wa DV ndiwambiri apa, womwe uyenera kukumbukiridwa musanayambe chithandizo. Amawonetsera matenda a shuga a 2 omwe samatha kudya komanso kuchita masewera olimbitsa thupi.

Analogue ndiotsika mtengo kuchokera ku ma ruble 158.

Akrikhin (Russia) Glidiab ndi amodzi mwamalo opindulitsa kwambiri a gliclazide. Imapezekanso m'mapiritsi, koma mulingo wa DV ndiwambiri apa, womwe uyenera kukumbukiridwa musanayambe chithandizo. Amawonetsera matenda a shuga a 2 omwe samatha kudya komanso kuchita masewera olimbitsa thupi.

Kufotokozera za mankhwalawa

Diabetes - Glyclazide imachokera ku sulfonylurea, mankhwala amkamwa a hypoglycemic omwe amasiyana ndi mankhwala omwewo mwa kukhalapo kwa mphete ya N ya heterocyclic yokhala ndi mgwirizano wa endocyclic.

Gliclazide imachepetsa kuchuluka kwa shuga m'magazi, ndikulimbikitsa kutulutsa kwa insulin ndi β-maselo a islets a Langerhans. Kuwonjezeka kwa kuchuluka kwa postprandial insulin ndi C-peptide kumapitirira pambuyo pa zaka 2 za mankhwala. Kuphatikiza pa momwe zimapangidwira kagayidwe kazakudya, gliclazide imakhala ndi mphamvu ya m'mitsempha.

Zokhudza insulin katulutsidwe

Mtundu wachiwiri wa matenda a shuga, mankhwalawa amabwezeretsa chiyambi champhamvu cha insulin chifukwa cha kuchuluka kwa glucose ndikuwonjezera gawo lachiwiri la insulin secretion. Kuwonjezeka kwakukulu kwa insulin katulutsidwe kumawonedwa poyankha kukondoweza chifukwa cha zakudya zomwe amapatsa ndi shuga.

Glyclazide amachepetsa chiopsezo cha mtsempha wamagazi ochepa, thrombosis, yomwe ingayambitse kukula kwa zovuta za matenda osokoneza bongo: kuletsa kwapang'onopang'ono kwa kuphatikiza kwa mapuloteni ndi kutsekeka komanso kuchepa kwa kuchuluka kwa zinthu zamagulu a cell (beta-thromboglobulin, thromboxane B2), komanso kubwezeretsanso kwa mafupa am'mimba. ndi kuchuluka ntchito ya minofu plasminogen activator.

Kuwongolera kwambiri kwa glycemic kutengera kugwiritsa ntchito mankhwalawa Diabeteson ® MB (glycosylated hemoglobin (HbA1c ® MB) ndikuwonjezera mlingo wake motsutsana ndi maziko (kapena m'malo mwake) wa chithandizo chokwanira musanawonjezere mankhwala ena a hypoglycemic (mwachitsanzo, metformin, alpha-glucosidase inhibitor, a thiazolidinedione derivative kapena insulini.) Pakati pa mankhwala a diabeteson ® MB a tsiku lililonse odwala omwe ali m'gulu lolamuliramo anthu anali 103 mg, mlingo waukulu wa tsiku ndi tsiku unali 120 mg.

Poyerekeza ndi kagwiritsidwe ntchito ka mankhwala a Diabeteson ® MB pagulu lolamulira glycemic control (pafupifupi kutsatira zaka 4.8, pafupifupi HbA1c 6.5%) poyerekeza ndi gulu lolamulira wamba (pafupifupi HbA1c 7.3%), kuchepetsedwa kwakukulu kwa 10% pachiwopsezo chophatikizika cha macro- ndi zovuta zazing'ono zam'mimba.

Ubwino unakwaniritsidwa pakuchepetsa kwambiri chiopsezo chaching'ono: zovuta zazikulu za microvascular ndi 14%, kuyambika ndi kupitilira kwa nephropathy ndi 21%, kupezeka kwa microalbuminuria ndi 9%, macroalbuminuria ndi 30% komanso kukula kwa aimpso ndi 11%.

Ubwino wowongolera glycemic kwambiri mutatenga Diabeteson ® MB sizinadalire zabwino zomwe zimapezeka ndi antihypertensive therapy.

Kufotokozera Kwazogulitsa

Diabetes ndi othandizira pa hypoglycemic komanso zotumphukira zomwe zimatengedwa pakamwa. Kusiyana kwake kufananizira ndi kukhalapo kwa mphete ya N-heterocyclic yokhala ndi chomangira cha endocyclic. Mankhwalawa amathandizira kupanga insulin ndi ma β-cell a islets a Langerhans ndikuchepetsa zomwe zili m'magazi.

Pambuyo pa zaka ziwiri zamankhwala, kuwonjezeka kwa C-peptide ndi insprandial insulin kumatsalira. Gawo lochita lachiwonetsero limawonetsa kukhudzika kwa mitsempha ndipo limakhudza kagayidwe kazachilengedwe. Mtundu wachiwiri wa matenda ashuga, umachulukitsa gawo lachiwiri la insulin katulutsidwe ndikubwezeretsa pachimake cha katulutsidwe ka shuga. Njira izi zimawonedwa makamaka ndi kuyambitsa kwake komanso poyankha kukondoweza, komwe kumachitika chifukwa cha chakudya.

Mankhwala amachepetsa chiopsezo cha thrombosis yaying'ono yamagazi ndi kukula kwa zovuta zomwe zimachitika chifukwa cha matenda ashuga. Pambuyo pa tsiku limodzi logwiritsira ntchito mankhwalawa, kuchuluka kwa metabolites ndi pioglitazone mu seramu yamagazi amakhalabe pamalo okwera.

Malangizo ogwiritsira ntchito

Mawuwo akuwonetsa zoletsa kumwa mankhwalawo. Milandu yake ikuluikulu zotsatirazi:

• matenda a shuga
• nthawi yodzala ndi kubereka mwana,
• kukanika kwambiri kwa hepatic ndi aimpso,
• kuchuluka kwa matupi a ketone ndi shuga wamagazi,
• tsankho lactose, sulfanilamide, gliclazide.

Mankhwalawa amaperekedwa kwa odwala akuluakulu okha. Piritsi imayenera kutengedwa kamodzi patsiku pakudya. Mlingo wambiri watsiku ndi tsiku ndi 120 mg. Mankhwalawa sangawonongeke komanso kutafuna, amayenera kutsukidwa ndi madzi osavuta. Ngati mungadumphe kumwa mankhwalawo, musagwiritse ntchito Mlingo wowerengeka.

Pa gawo loyambirira la mankhwala, mlingo ndi 30 mg. Ngati ndi kotheka, ukuwonjezeka ndi katswiri palibe kale kuposa masiku 40 atasankhidwa kale. Odwala a zaka zopitilira 65 safuna kusintha kwa Mlingo. Pa chithandizo, nthawi ya kuchotsedwa kwa mankhwala am'mbuyomu iyenera kuganiziridwa. Mukamamwa mankhwalawa, zimachitika zovuta kuzimvera. Izi zikuphatikiza:

• kulephera kudziwa
• kugona kwambiri kapena kusowa tulo,
• chisangalalo chamanjenje
• zosavomerezeka
• kukokana ndi kufooka wamba,
• Kuzindikira kwa vuto, chizungulire.

Analogs ndi choloweza mmalo mwa mankhwalawo

Mankhwala ali ndi mtengo wokwera kwambiri. Ma dialogon a diabetes ndi m'malo mwake amaimiridwa ndi mankhwala otsatirawa:

• Diabetesalong
• Glyclazide
• Glidiab
• Diabefarm MV,
• Predian
• Gulcostabil,
• Piroglar.

Diabetesalong - Analogue yotsika mtengo ya Diabeteson, mawu ofanana omwe amawonjezera kupanga kwa insulini, chidwi cha zotumphukira ndipo amachepetsa kuchuluka kwa shuga m'magazi. Osati osokoneza bongo ngakhale atatha zaka 3 akugwiritsidwa ntchito. Mankhwala amachepetsa postprandial hyperglycemia, kubwezeretsa koyamba kuchuluka kwa insulin, kumachepetsa nthawi pakati pakudya ndi insulin. Mu chiwindi, mankhwalawa amachepetsa mapangidwe a shuga ndikuwonjezera magwiridwe ake.

Chithandizo chogwira ntchito chimachepetsa kukoka kwam'mimba komanso chakudya cha metabolism, kumachepetsa chiopsezo cha thrombosis ndikuyambiranso ntchito ya minofu ya plasminogen activator.

Gliclazide - Uwu ndi mtundu wa mankhwala osokoneza bongo omwe umapangidwira mkati. Zimaphatikizira mphete ya heterocyclic yokhala ndi chomangira cha endocyclic. Mankhwala amathandizira kupanga insulin komanso amachepetsa kuchuluka kwa shuga. Pambuyo pa zaka zitatu zamankhwala, kuwonjezereka kwa ndende ya C-peptide ndi insprandial insulin kumatsalira. The yogwira mawonekedwe limawonetsa hemovascular zochita ndipo zimakhudza kagayidwe kachakudya metabolism. Kugwiritsa ntchito mankhwala kumachepetsa chiopsezo cha zovuta za matenda ashuga.

Glidiab Ndi mankhwala a 2-sulfonylurea otumphukira ndi hypoglycemic. Imakongoletsa kugwiririra ntchito kwa glucose insulin, chinsinsi cha zotumphukira ndipo imakhudzanso kupuma kwa insulini, imalimbikitsa zomwe zimachitika mu minyewa yam'mimba ya glycogen synthetase, ndikuchepetsa kuchuluka kwa hyperglycemia mutatha kudya. Kugwiritsa ntchito mankhwalawa kuyenera kuyamba motsutsana ndi chakudya chamafuta ochepa.

Ndikulimbikitsidwa kuyang'anira kuchuluka kwa glucose m'magazi mukatha kudya komanso pamimba yopanda kanthu. Mlingo umasinthidwa kuti mukhale ndi nkhawa kapena thupi.

Diabefarm MV - Ichi ndi chithunzi cha Diabeteson 60, womwe ndi mankhwala a hypoglycemic komanso ogwirizana ndi m'badwo wachiwiri wa zotumphukira za sulfonylurea. Imayambitsa kupanga insulin ndi maselo a kapamba ndi zochita za ma intracellular enzymes. Mankhwalawa ndi othandiza kwambiri ku mtundu wa 2 osagwiritsa ntchito insulin wodwala matenda ashuga okhala ndi matenda ashuga komanso ngati prophylactic ya michere ya cellcirculatory.

Predian - mankhwala a synthetic. Itha kugulidwa ngati mapiritsi okhala ndi mulingo wa 0,08 g, yokhazikitsidwa pabokosi la makatoni. Chithandizo chogwira chimatsitsa magazi ndikuchepetsa shuga. Mankhwalawa amayenera kuyamba ndi theka la mapiritsi. Mankhwalawa sangaphatikizidwe ndi acetylsalicylic acid, butadione, amidopyrine chifukwa chowopseza hypoglycemia.

Glucostabil bwino fibrinolytic mtima ntchito, amachepetsa kukula kwa parietal thrombus, kuphatikiza kupatsidwa zinthu za m'magazi komanso zomatira. Mankhwalawa amachulukitsa microcirculation, kuchuluka kwa HDL-C, kumachepetsa cholesterol, mphamvu yamitsempha yamagazi kupita ku adrenaline ndipo kumalepheretsa kukula kwa atherosulinosis ndi microthrombosis. Kutsika kwa proteinuria kwa nthawi yayitali kumadziwika motsutsana ndi kugwiritsidwa ntchito kwa nthawi yayitali kwa gliclazide mu matenda ashuga.

Phuli - hypoglycemic mankhwala amkamwa komanso kusankha kwa gamma receptor agonist mwamphamvu. Gawo lolimbikira likuwonetsa kusintha kwa majini omwe akukhudzidwa ndi kuphulika kwa lipid ndi kayendedwe ka shuga. Mu chiwindi ndi zotumphukira zimakhala, amachepetsa kukana insulin. Mtundu wachiwiri wa matenda a shuga, amachepetsa hemoglobin wa m'magazi ndi insulin m'madzi am'magazi.

Mutha kudziwa zomwe Diabeteson ikhoza kusintha ndi dokotala. Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa nokha, chifukwa izi zimabweretsa zotsatira zoyipa.

Analogs popanga ndi chisonyezo chogwiritsidwa ntchito

Mndandanda womwe uli pamwambapa wa analogies ya mankhwala, omwe akuwonetsa m'malo a Diabeteson MR, ndizabwino kwambiri chifukwa zimakhala ndi zinthu zomwe zimagwirizana ndipo zimagwirana molingana ndi chisonyezo chogwiritsidwa ntchito

Analogs mwa chisonyezo ndi njira yogwiritsira ntchito

Kuphatikizika kosiyanasiyana, kungagwirizane mukuwonetsa komanso momwe mungagwiritsire ntchito

Kodi mungapeze bwanji analogue yotsika mtengo ya mankhwala okwera mtengo?

Kuti mupeze chiwonetsero chotsika mtengo cha mankhwala, chofananira kapena chofanana, choyambirira timalimbikitsa kulabadira kapangidwe kake, zomwe ndi zinthu zomwezo zomwe zikugwiritsidwa ntchito ndikuwonetsa. Zomwe zimagwiritsidwanso mosiyanasiyana ndi mankhwalawa zimawonetsa kuti mankhwalawo ndi ofanana ndi mankhwalawo, monga mankhwala ena kapena mitundu ina. Komabe, musaiwale za zovuta zomwe zimagwiritsidwa ntchito ndi mankhwala ofanana, omwe angakhudze chitetezo ndi kugwiranso ntchito. Musaiwale za malangizo a madotolo, kudzipereka nokha kungawononge thanzi lanu, chifukwa chake onani dokotala wanu musanagwiritse ntchito mankhwala.

Diabeteson MR Mtengo

Pamasamba omwe ali pansipa, mutha kupeza mitengo ya MR Diabeteson ndikuwona ngati pali pharmacy yapafupi

• Mtengo wa Diabeteson MR ku Russia
• Mtengo wa Diabeteson MR ku Ukraine
• Mtengo wa Diabeteson MR ku Kazakhstan