CardiASK: malangizo ogwiritsira ntchito

CardiASK ndi chida chamakono cha antiplatelet chomwe chimalepheretsa kupangika kwa magazi, chimatchedwa anti-yotupa, antipyretic ndi analgesic.

Dzina lachi Latin: CardiASK.

Yogwira pophika: Acetylsalicylic acid.

Wopanga mankhwala: Canonpharma, Russia.

Piritsi limodzi la CardiASA lili ndi 50 kapena 100 mg ya acetylsalicylic acid.

Zomwe zimathandizirazi zimaphatikizapo wowuma chimanga, calcium stearate, lactose, mafuta a castor, cellcrystalline cellulose, pakati pa 80, plasdon K-90, plasdon S-630, talc, titanium dioxide, collicate MAE 100P, propylene glycol.

Kutulutsa Fomu

CardiASK imapezeka mu mapiritsi okhala ndi interic. Mapiritsi oyera ali ndi mawonekedwe ozungulira, a biconvex okhala ndi mawonekedwe osalala komanso owala (kukhuthala kumaloledwa).

Mapiritsi amapezeka mu zidutswa 10 m'matumba a blister. Mapaketi a Contour amadzaza pamatoni a 1, 2, 3.

Pharmacokinetics ndi pharmacodynamics

CardiASK ndi othandizira antiplatelet ndi NSAIDs. Njira yayikulu yogwiritsira ntchito mankhwalawa ndi kulephera kusintha kwa puloteni ya cycloo oxygenase. Zotsatira zake, pali cholepheretsa kapangidwe ka thromboxane A₂ ndi kuponderezana kwa kuphatikiza kuphatikizira kwa maselo. CardiASK imakhala ndi antipyretic, anti-kutupa ndi analgesic kwenikweni.

Mafuta a acetylsalicylic acid amachitidwa kumtunda kwa matumbo aang'ono. Kuchuluka kwa zinthu zomwe zili m'magazi kumafikira maola atatu atatha kumwa mankhwalawa. Acetylsalicylic acid imatha kugaya pang'ono m'chiwindi, motero imapanga metabolites yokhala ndi ntchito yochepera. Pulogalamu yogwira imapukusidwa kudzera mu kwamikodzo machitidwe osasinthika komanso mawonekedwe a metabolites. Hafu ya moyo wa yogwira mankhwala osasinthika ndi mphindi 15, metabolites - 3 maola.

CardiASK amalembedwa motere:

ndi angina pectoris,
ngati prophylaxis wa pachimake myocardial infarction, makamaka odwala okalamba odwala matenda ashuga, kunenepa kwambiri, matenda oopsa kapena hyperlipidemia,
Monga prophylaxis ya matenda amisala,
popewa thromboembolism pambuyo opaleshoni kapena njira zowukira,
ngati prophylactic yomwe imalepheretsa ngozi zam'magazi,
popewa kukula kwamitsempha yotupa,
Monga prophylactic popewa pulmonary embolism ndi nthambi zake.

Contraindication

CardiASK imakhudzidwa motere:

wokhala ndi zilonda zam'mimba,
pamaso pa mphumu ya bronchial,
ndi magazi m'mimba,
Ngati pali vuto ndi impso,
pa nthawi ya mkaka,
mu I ndi II trimester wa mimba,
osakwana zaka 18,
ndi "pririn triad" (Fernand-Vidal triad),
pamaso pa aimpso ndi chiwindi kulephera,
ndi hemorrhagic diathesis,
Ngati mukumwa methotrexate mu mankhwala oposa 15 mg pa sabata,
Pamaso pa hypersensitivity chachikulu yogwira mankhwala ndi zina zothandiza za mankhwala.

CardiAAS amalembedwa mosamala kwa odwala omwe ali ndi gout, hyperuricemia, zotupa ndi magazi m'matumbo am'mimba, komanso matenda a kupuma kwamatenda osakhazikika. CardiAAS imagwiritsidwanso ntchito mosamala kwa anthu omwe ali ndi hay fever, polyposis ya mucosa yammphuno ndi vitamini K.

Njira yogwiritsira ntchito

CardiASK tikulimbikitsidwa kuti idyedwe musanadye. Mapiritsi a pakamwa ayenera kutsukidwa ndi madzi ambiri. Kulandila kwa CardiASK ya mankhwala kumapereka mtundu wina wa mankhwala. Koma nthawi zambiri muyezo umodzi wa achikulire ndi 150 mg - 2 g, ndipo tsiku lililonse mlingo wa 150 mg ndi 8 g. Mlingo wa tsiku ndi tsiku umagawidwa mu 2-6 Mlingo patsiku.

Ana ochepera zaka 18 amatenga CardiASK pamlingo wa 10-15 mg pa kilogalamu imodzi ya kulemera kwa mwana. Ndi bwino kugawa tsiku ndi tsiku mlingo waukulu.

100 mg ya mankhwalawa amathandizidwa kuti azitha kulowetsedwa m'mnyewa wam'mawere pakachulukidwe, komanso kupewa ngozi zam'magazi.

Ndondomeko yofanana ya mankhwalawa iyenera kutumizidwa ndi adokotala okha. CardiASK cholinga chake ndikugwiritsa ntchito nthawi yayitali.

Chenjezo ndi malingaliro

CardiASK imatha kuyambitsa mphumu ndi bronchospasm. Hayfever, thupi lawo siligwirizana, polyposis ya mucosa wammphuno ndi matenda kupuma matenda akhoza kukhala chiopsezo.

CardiASK imatha kuyambitsa magazi osiyanasiyana mkati mwa opareshoni. Kuphatikizidwa kwa CardiASA ndi mankhwala a thrombotic, anticoagulant ndi antiplatelet kumapangitsa kuti magazi azituluka.

Ngati wodwalayo ali ndi vuto lotchedwa gout, ndiye kuti CardiASK pamagetsi itachepa ingayambitse matendawa.

Mlingo wokwera wa CardiASA ungayambitse vuto la hypoglycemic, mawonekedwe awa ayenera kuganiziridwa kwa odwala omwe ali ndi matenda ashuga.

Sitikulimbikitsidwa kuphatikiza CardiASK ndi ibuprofen.

CardiASK mu milingo yayitali imatha kutulutsa magazi m'mimba.

Mowa, wotengedwa limodzi ndi mankhwalawa, ungawononge mucosa wam'mimba ndikuwonjezera nthawi yotuluka magazi.

Zotsatira zoyipa

Malinga ndi kafukufuku ndi ndemanga kuchokera kwa ogula, CardiASK ikhoza kuwonetsa zovuta izi:

kusanza, kutentha kwa mtima, nseru, kupweteka m'mimba, zilonda zam'mimba, magazi am'mimba, kuchuluka kwa hepatic transaminases,
bronchospasm
tinnitus ndi chizungulire,
magazi ochulukirapo, kawirikawiri, kuchepa kwa magazi kunadziwika,
Edema ya Quincke, urticaria ndi zochitika zosiyanasiyana za anaphylactic,

Pazizindikiro zoyambirira za zoyipa, ndikofunikira kusiya mankhwalawa ndikupita kuchipatala.

Bongo

Mulingo wambiri wa mankhwala osokoneza bongo akufotokozedwa m'mphuno ndi kusanza, chizungulire, tinnitus, kutaya khutu ndi chisokonezo. Mankhwala osokoneza bongo owonjezereka amawonetsedwa ngati chikomokere, kupuma komanso mtima kulephera, kutentha thupi, ketoacidosis, hyperventilation, kupuma kwa alkalosis ndi hypoglycemia. Mankhwala owopsa kwambiri okalamba.

Pafupifupi kuchuluka kwa bongo kumatha kuchepetsa kuchepetsa. Zambiri bongo amafuna kuchipatala, chapamimba thovu, kufanana kwa asidi-maziko, kukakamizidwa zamchere diuresis, hemodialysis ndi kulowetsedwa mankhwala. M'pofunikanso kupatsa ozunzidwa makala ogwirira ntchito ndi kuwonetsa monga chithandizo.

Kugwirizana kwina ndi mankhwala ena

CardiASK imawonjezera zochizira zotsatira za methotrexate, thrombolytics, antiplatelet agents, hypoglycemic othandizira, digoxin, heparin, anticoagulants osadziwika, valproic acid.

Mavuto osafunikira ochokera ku hematopoiesis amatha chifukwa cha kuphatikiza kwa CardiASK ndi anticoagulants, thrombolytics, methotrexate ndi antiplatelet agents.

CardiASK imafooketsa achire zotsatira za uricosuric mankhwala: ACE zoletsa, benzbromarone, okodzetsa.

Mankhwala

Makina a antiplatelet zochita za acetylsalicylic acid (ASA) ndi choletsa chosasintha cha cycloo oxygenase (COX-1). Izi zimabweretsa kuponderezana kwa kuphatikizana kwa maselo ndi kuletsa kwa thromboxane A kaphatikizidwe.₂. Mphamvu ya antiplatelet imatchulidwa kwambiri chifukwa cha kupanikizana, omwe amalephera kupanganso cycloo oxygenase. Kutalika kwa mphamvu ya antiplatelet ndi pafupifupi masiku 7 pambuyo pa limodzi, ndipo kumatchulidwa kwambiri mwa amuna amuna kuposa akazi.

ASA imawonjezera ntchito ya fibrinolytic ya plasma yamagazi ndikuchepetsa zomwe zili ndi mavitamini a Vit-K otengera mavitamini (X, IX, VII, II).

Malangizo ogwiritsira ntchito Cardiasca

Mankhwalawa amagwiritsidwa ntchito pakamwa musanadye. Mapiritsi ayenera kutsukidwa ndi madzi ambiri.

Malangizo ogwiritsira ntchito Cardiask imapereka malangizo amodzi:

Akuluakulu, muyezo umodzi umatha kuchoka pa 150 mg mpaka 2 ga, ndipo mlingo wa tsiku ndi tsiku, kuchokera ku 150 mg mpaka 8 g. Mankhwala amatengedwa 2-6 tsiku lililonse,
Kwa ana, muyezo umodzi ndi 10-15 mg pa kilogalamu. Mapiritsi amatengedwa mpaka 5 patsiku,
pachimake myocardial infarationkomanso ndi cholinga chopewa sitirokondi ngozi yamitsempha ndikulimbikitsa kumwa 100 mg ya mankhwala patsiku.

Mlingo womaliza komanso mulingo woyenera uyenera kuvomerezedwa ndi adokotala. Malangizo ogwiritsira ntchito Cardiasca akuti mankhwalawa adapangidwa kuti azigwiritsidwa ntchito kwa nthawi yayitali. Kutalika kwa maphunzirowa kumatsimikizidwanso ndi adokotala.

Kuchita

Mankhwalawa amalimbikitsa machitidwe a mankhwala otsatirawa:

Zotsatira zoyipa kuchokera ku ziwalo za hemopoietic zimatha kupezeka ndi kuphatikiza kwa Cardiaska ndi Methotrexate, anticoagulants, antiplatelet agents, manga.

Mankhwala amachepetsa mphamvu ya uricosuric mankhwala: Benzbromarone, Zodzikongoletsera, ACE zoletsa.

Tsiku lotha ntchito

Moyo wa alumali ndi zaka 2.

Cardiask ili ndi fanizo zotsatirazi:

Ndemanga pa mtima Cardiask ndizabwino kwambiri. Pamabwalo, ambiri ali ndi chidwi chofuna kudziwa ngati chida ichi ndichothandiza kuposa ma fanizo ake. Palibe yankho lomveka bwino pafunso ili, chifukwa pali mankhwala ofanana ndipo onse ali ndi mawonekedwe awo.

Ndemanga za akatswiri pa Cardiasca zilinso zabwino. Nthawi zambiri amapereka kwa kupewa myocardial infaration, sitirokondi thrombosis osiyanasiyana etiology.

Zizindikiro zogwiritsidwa ntchito

Amagwiritsidwa ntchito kupewa:

pachimake myocardial infaration pamaso pa zinthu zoopsa monga ochepa matenda oopsa, matenda a shuga, Hyperlipidemia, ukalamba, kusuta ndi kunenepa kwambiri,
myocardial infaration,
kusuntha kwakanthawi kwa ubongo,
mitsempha yotupa ya m'mimba komanso pulmonary embolism,
thromboembolism atatha kulowerera ndi kuchitira opaleshoni mitsempha yamagazi,
sitiroko.

Kuphatikiza apo, kugwiritsidwa ntchito kumalimbikitsidwa kwa angina osakhazikika.

Malangizo ogwiritsira ntchito Cardiask (njira ndi Mlingo)

Mapiritsi amatengedwa pakamwa musanadye. Mankhwalawa adapangidwira kuti agwiritsidwe ntchito, nthawi yake yomwe adokotala amatsimikiza.

Kupewera koyambirira kwa kulowetsedwa kwachimake myocardial pamaso pa zinthu zoopsa: 50-100 mg / tsiku. Kupewa kubwerezanso kwa myocardial infarction, angina osakhazikika: 50-100 mg / tsiku.
Angina wosakhazikika (ndi kukayikira komwe kumayambitsa kupweteka kwachimake): 50-100 mg / tsiku.
Kupewa kwa thromboembolism pambuyo pakuchita opaleshoni ndikulowerera kwa mitsempha yolowerera: 50-100 mg / tsiku.
Kupewa kwa ischemic sitiroko ndi kuchepa kwakanthawi kwamisempha: 50-100 mg / tsiku, vein thrombosis komanso pulmonary embolism ndi nthambi zake: 50-100 mg / tsiku.

Zotsatira zoyipa

Kutenga Cardiask kumatha kuyambitsa zotsatirazi:

Kuchokera pamimba: kukhumudwa, kusanza, kusanza, kupweteka kwam'mimba, magazi am'mimba, zilonda zam'mimba za duodenum ndi m'mimba, kuchuluka kwa hepatic transaminases.
Kuchokera kuzungulira kwa magazi: Kuchulukitsa kwa magazi, nthawi zina - kuchepa magazi.
Kuchokera pakupuma dongosolo: bronchospasm.
Kuchokera kumbali ya chapakati mantha dongosolo: tinnitus, chizungulire, mutu.
Zotsatira zamagetsi: edema ya Quincke, urticaria ndi anaphylactic.

Zotsatira za pharmacological

Cardiask ili ndi antiplatelet athari, yokhazikitsidwa ndi choletsa chosasinthika cha COX-1, chomwe chimalepheretsa kaphatikizidwe ka thromboxane A2 ndikulepheretsa kuphatikizana kwa mapulateleti. Cardiask ilinso ndi njira zina zoponderezera kuphatikizira kwa kupatsidwa zinthu za m'magazi, zomwe zimapangitsa kuti ikhale yothandiza mu matenda osiyanasiyana a mtima. Mlingo wambiri, mankhwalawa amakhalanso ndi analgesic, anti-yotupa komanso antipyretic thupi.

Malangizo apadera

Zimatha kupangitsa kukhazikika kwa bronchospasm kapena kupangitsa kufalikira kwa mphumu. Kuwonjezeka kwa chiwopsezo cha mavuto mu mbiri ya hay fever, mphuno ya m'mphuno, matenda oyamba ndi kupuma komanso chizolowezi chomwa thupi lawo siligwirizana.
Mphamvu yolepheretsa ya ASA kuphatikizidwa kwa kupatsidwa zinthu za m'magazi imapitirira masiku angapo pambuyo pa kukhazikitsa. Izi zimawonjezera chiopsezo chakutaya magazi nthawi ya opareshoni kapena nthawi ya postoperative. Ngati kuli kofunika kuthetseratu magazi, ndikofunikira kusiya kwathunthu kugwiritsa ntchito mankhwalawa.
Mlingo wochepetsetsa, umatha kupangitsa kuti gout ikhale mwa anthu omwe achepetsa uric acid excretion.
Mlingo wambiri, umakhala ndi vuto la hypoglycemic, ndikofunikira kuganizira popereka odwala omwe ali ndi matenda osokoneza bongo omwe amalandila mankhwala a hypoglycemic.
Ndi kuphatikiza kwa mankhwala osokoneza bongo ndi salicylates, muyenera kukumbukira kuti pamankhwala, chithandizo chotsirizidwa m'magazi chimachepetsedwa, ndipo atatha kufalitsa, mankhwala ochulukirapo a salicylates amatha.
Kuchulukitsa mlingo wa acetylsalicylic acid kumalumikizidwa ndi chiopsezo chakutulutsa magazi m'matumbo.

Kuyanjana kwa mankhwala osokoneza bongo

Pogwiritsa ntchito munthawi yomweyo mankhwala osokoneza bongo komanso methotrexate, asidi acetylsalicylic imawonjezera mphamvu yotsirizira chifukwa kuchepa kwa mawonekedwe ake aimpso ndi kuchoka ku maubwenzi ndi mapuloteni a plasma.
Imawonjezera mphamvu ya ma anticoagulants osalunjika ndi heparin chifukwa cha kuwonongeka kwa mapulogalamu am'matumbo ndikuchotsa ma anticoagulants osagwirizana ndi ma protein onse a plasma.
Akaphatikizidwa, zimawonjezera mphamvu ya antiplatelet ndi thrombolytic mankhwala.
Chifukwa cha hypoglycemic zotsatira za acetylsalicylic acid, kugwiritsa ntchito mankhwalawa muyezo waukulu kumathandizira zochita za insulin ndi zotumphukira za sulfonylurea.
Imawonjezera zotsatira za digoxin, ndikuchulukitsa kuchuluka kwake kwa plasma. Imalimbikitsanso machitidwe a valproic acid, ndikuyichotsa kumayanjano ndi mapuloteni a plasma.
Ndi munthawi yomweyo kugwiritsa ntchito mankhwala osokoneza bongo komanso uricosuric, acetylsalicylic acid imafooketsa mphamvu zawo chifukwa cha kuchepa kwa uric acid.
Akaphatikizidwa ndi Mowa, zotsatira zowonjezera zimawonedwa.

Mtengo mumafakisi

Mtengo wa Cardiask wa phukusi limodzi umayambira ku ma ruble 45.

Malongosoledwe patsamba lino ndi mtundu wosavuta wa mtundu wazovomerezeka zamankhwala. Chidziwitsocho chimaperekedwa kuti chizidziwitso chokha komanso sikuti chitsogozo chodzidzipangira nokha. Musanagwiritse ntchito mankhwalawa, muyenera kufunsa katswiri kuti mudziwe malangizo omwe amavomerezedwa ndi wopanga.

Malangizo ogwiritsira ntchito CardiASK: njira ndi mlingo

CardiASK iyenera kumwedwa pakamwa asanadye, ndi madzi ambiri.

Kupewa kwa kulowetsedwa kwamatumbo oyamba: 100-200 mg patsiku kapena 300 mg tsiku lililonse (ndikulimbikitsidwa kutafuna piritsi loyambirira kuti lithe msanga),
Kupewa kwa kuphwanya kwachimake myocardial pamaso panu pazowopsa: 100 mg patsiku kapena 300 mg tsiku lililonse lililonse,
Osakhazikika angina pectoris, komanso kupewa pafupipafupi myocardial infarction, sitiroko, matenda osakhalitsa a mtima
Kupewa kwambiri kwamitsempha yotupa, thromboembolism yam'mitsempha yamagazi ndi nthambi zake: 100-200 mg patsiku kapena 300 mg tsiku lililonse lililonse.

Kutalika kwa chithandizo kumatsimikiziridwa payekhapayekha, koma CardiASK imagwiritsidwa ntchito kwa nthawi yayitali.

Mimba komanso kuyamwa

Kutenga CardiASA muyezo waukulu mu nthawi yayitali ya mimba kumawonjezera mwayi wokhala ndi vuto losakhazikika kwa mwana wosabadwa (vuto la mtima, kugawanika kwa palate yapamwamba), chifukwa chake, cholinga chake chimaphatikizidwa panthawiyi. Mu nyengo yachiwiri ya kubereka, ma salicylates amayikidwa pokhapokha pokhapokha pobwera maubwino a mayi ndi chiwopsezo cha mwana wosabadwayo, makamaka masiku osaposa 150 mg komanso kwa nthawi yochepa.

Mu gawo lachitatu lokhala ndi pakati, CardiASC yokhala ndi Mlingo wambiri (kupitilira 300 mg patsiku) imapangitsa magazi kutuluka m'mimba mwa mayi ndi mwana wosabadwa, kutsekeka kwa nthawi yayitali m'mimba ana. Chifukwa chake, kugwiritsa ntchito mankhwalawa panthawiyi ndikuloledwa.

ASA ndi ma metabolites ang'onoang'ono oyenda amapita mkaka wa m'mawere. Mwangozi makonzedwe a mankhwala pa nthawi yoyamwitsa sizimayambitsa kusokonezeka kwa khanda ndipo sikutanthauza kuti kuthetsedwera kwa chakudya. Komabe, ndimankhwala okhazikika omwe mumakhala nawo kapena muli ndi vuto lalikulu la CardiASA, kuyamwa kuyenera kuyimitsidwa nthawi yomweyo.

Ndemanga za CardiASK

Malinga ndi ndemanga, CardiASK imagwira ntchito ndipo ili ndi tanthauzo lothandizira. Komabe, sizotheka kuyerekeza mphamvu ya mankhwalawa ndi mawonekedwe ake. Komanso, odwala amakonda mtengo wake wotsika.

Akatswiri amalankhulanso bwino za mankhwalawa. Nthawi zambiri CardiASK imalembedwa kupewa matenda a thrombosis osiyanasiyana a etiology, stroko ndi myocardial infarction.