Matebwe okhala ndi kuchuluka kwa insulin (pofika zaka)
Chamoyo chogwira ntchito kwambiri kwokhudzana ndi katemera wa amkati (mkati), apo ayi, insulin, ndi imodzi mwazomwe zimayendetsa metabolic mu thupi. Kuchuluka kwake kapena kuchepa kwa ndende kumawonetsa zonyansa mu endocrine system. Miyezo ya mahomoni imakwera pang'onopang'ono kutengera zaka za munthu. Kuphatikiza apo, muyezo wa insulin m'magazi a akazi umasintha mu nthawi ya perinatal. Izi zimafuna chidwi chochulukirapo kuchokera kwa dokotala, chifukwa zingasonyeze kukula kwa matenda ashuga - mawonekedwe apadera a matenda omwe amayambitsidwa ndi kusalinganika kwa mahomoni panthawi yapakati.
About insulin
Pancreas imayang'anira kupanga insulini - chinthu chapadera chomwe chimagwira ntchito zonse za exocrine (exocrine) ndi intrasecretory (endocrine).
Cholinga chachikulu cha mahormoni ndicho kutsitsa kagayidwe kazakudya ndi kuperekera kwakanthawi kwa shuga, monga gwero lamphamvu, m'maselo ndi minyewa ya thupi.
Kuonetsetsa ntchito yofunika, insulin imakhudzidwa motere:
- Kupanga kwa glycogen (insulini imathandiza kuphatikiza ndi kusungitsa shuga m'magawo obwezeretsanso maselo ndi mphamvu, ngati itasowa),
- kuletsa kuwonongeka kwa amino acid kukhala mashuga osavuta,
- kayendedwe ka kuchuluka kwa ma ketones (matupi a acetone) m'magazi (mahomoni amawongolera kuchuluka kwa ma ketoni, amawalepheretsa kudziunjikira),
- mapuloteni kaphatikizidwe (amayambitsa kupanga kwawo, ndipo amateteza kuwola),
- kapangidwe ka RNA (ribonucleic acid), yomwe imakhazikitsa ndi kufalitsa chidziwitso cha cholowa.
Popanda insulin, thupi silitha kugwira ntchito mokwanira. Glucose kuchokera ku chakudya amakhala ndi magazi, ndipo maselo salandila mphamvu zochuluka. Pali matenda a shuga a mtundu woyamba, apo ayi amadalira insulin. Kuti munthu akhale ndi thanzi labwinobwino, amafunika kuti azizidwanso thupi ndi insulin yodalira mankhwala. Zomwe zimachitika pakapangidwe ka insulin mokwanira, koma chifukwa chophwanya mpweya wa metabolism, maselo sangathe kuyamwa, kukulira kwa insulin - mtundu 2 matenda a shuga.
Kuyeza kwa mulingo
Mluza umalowetsedwa ndi chakudya. Kuchuluka kwake kumatengera zinthu zomwe zimadyedwa. Zakudya zokhala ndi shuga wambiri wosavuta (glucose, fructose, lactose, etc.) zimathandizira kutulutsa kochuluka kwa shuga owonjezera m'magazi, ndipo kapamba amayenera kuphatikiza insulin yambiri. Chifukwa chake, kuchuluka kwa insulin m'magazi kumawonjezeka ndikatha kudya. Zotsatira zakuwunika bwino zitha kupezeka pamimba yopanda kanthu.
Pofufuza, magazi a venous amagwiritsidwa ntchito. Pamaso kusanthula, ziyenera kukwaniritsidwa:
- osamwa mowa masiku atatu,
- osamadya kwa maola 10-12,
- ngati ndi kotheka, kanizani mankhwala m'masiku awiri.
M'mawa kusanachitike kusanthula, madzi oyera okha ndi omwe amaloledwa.
Zizindikiro mwa akazi
Pogwiritsa ntchito ndalama zambiri, thupi limagwiritsa ntchito shuga wambiri. Kuti shuga asadziunjike m'magazi, koma amatengedwa monga momwe amawalangizira, kapamba amakakamizidwa kuwonjezera insulin. Mwa akazi, kupanga insulin kumadaliranso tsogolo la mahomoni munthawi yopatsidwa moyo.
Hormone Digital maadili
Ana achikazi | Amayi achikulire | Zaka 60+ | Nthawi yamapeto |
kuyambira 3 mpaka 20 mkU / ml | kuyambira 3 mpaka 25 mcU / ml | kuyambira 6 mpaka 35 mkU / ml | kuyambira 6 mpaka 27 mkU / ml |
Kupatuka pang'ono panjira yololedwa kumaloledwa pakati pa atsikana akatha msambo. Kuti mudziwe kuchuluka kwake komanso kuchuluka kwa mahomoni, kuyezetsa magazi kumayikidwa ndi katundu pazolekerera shuga. Kuyamwa koyambirira kumachitika pamimba yopanda kanthu, ndiye kuti wodwalayo ayenera kumwa yankho la madzi ndi glucose. Pambuyo maola awiri, kusanthula kumabwerezedwa. Pambuyo ponyamula shuga, zosintha zotsatirazi za insulin ndizomwe zimachitika:
- kwa amayi akuluakulu - 13-15 mkU / ml,
- munthawi yamatenda kuyambira 16 mpaka 17 mcU / ml.
Kusanthula kwamtunduwu kumapangidwira zifukwa zamankhwala zodwala matenda ashuga (mtundu 1 kapena 2), matenda a shuga gestational, ndi zina za pathologies. Kuyesa kungachitike osati ndi magazi okha, komanso mkamwa.
Zizindikiro za zizindikiro zosakhazikika
Zizindikiro za insulin yokwanira kapena yotsika ndizophatikizira:
- polydipsia (kumva ludzu kosatha),
- polacuria (pafupipafupi kufuna kutulutsa chikhodzodzo),
- kuyanika komanso khungu lolimba, totupa pa khungu,
- polyphagy (kuchuluka kudya),
- vegetovascular matenda.
Zizindikiro za akazi ndi:
- kulephera kubereka mwana (kubereka),
- thukuta kwambiri (hyperhidrosis),
- maonekedwe a mibadwo ya pa nkhope.
Chizindikiro chodziwika bwino chimadziwonetsa mu kusamba. Kukhumudwitsa sikuyenera kunyalanyazidwa, kuwalumikiza kokha ndi mawonekedwe a kusintha kwa msambo. Kusakhazikika kwa insulin kumatha kuwonetsa matenda akulu.
Zifukwa zopatuka
Kusagwirizana ndi zomwe zili mu zotsatira zakuwunikira kumatha kuchitika pazinthu ziwiri zazikulu: moyo wa mayi komanso kupezeka kwa matenda. Gawo loyamba limaphatikizapo kupsinjika (kupsinjika kwa nthawi zonse)
Zomwe zimayambitsa izi zimatha kuthetsedwa pogwiritsa ntchito kukonza kwamunthu payekha komanso momwe akukhalira. M'mikhalidwe yabwino, insulin yambiri imasintha. Mlanduwo pamene kupatuka kwa chizindikiro cha insulin mu mkazi kumayambitsidwa ndi njira yothandizira thupi, njira zowonjezera zowonjezera zimayikidwa.
Mulingo wokwera
Kukula kamodzi kokha kwa insulin sikumakhala chizindikiro cha matendawo. Komabe, ngati mitengo yokhazikika imawonedwa kwakanthawi, izi zitha kuonetsa kukhalapo kwa izi:
- shuga wosadalira insulin (mtundu wachiwiri wa matenda),
- kuchuluka kwa cortisol (mahomoni a adrenal cortex), apo ayi Itsenko-Cushing's syndrome,
- mitundu ingapo padziko thumba losunga mazira mu mawonekedwe a ma cysts (polycystic ovary),
- zotupa za adrenal,
- benign neoplasm (insulinoma) kapena khansa ya kapamba,
- kusokonekera magwiridwe a ubongo pisititary zapakati (acromegaly),
- minofu dystrophy,
- chifuwa chachikulu (nthawi zambiri, chovuta kapena chotsogola),
- kunenepa kwambiri kwa digiri ya III ndi IV.
Mulingo wotsika
Kuperewera kwa insulin kumayendera limodzi ndi hyperglycemia (kuchuluka kwa shuga m'magazi), nthawi zambiri, ndi chizindikiro cha matenda a shuga 1. Izi matenda a endocrine dongosolo sizitanthauza kuti kuthetseratu. Matendawa ndi osachiritsika, popanda mankhwala a insulin, moyo wa wodwalayo uli pachiwopsezo.
Kuchuluka kwa insulin kumatha kuwonetsa kukhalapo kwa matenda opatsirana:
- mavairasi (fuluwenza, HIV, nsungu, nthomba, hepatitis A, B, C, E),
- bacteria (salmonellosis, kamwazi, chifuwa chachikulu),
- fungal (candidiasis, cryptococcosis ndi mycoses ena),
- parasitic (giardiasis, trichomoniasis, toxoplasmosis, etc.),
- helminthic (ascariasis, enterobiasis, toxocariasis, ndi zina).
Kuchepa kwamankhwala a insulin kumabweretsa kuchepa kwa kupanga kwa ma tropic mahomoni ndi pituitary kapena hypothalamus (hypopituitarism). Chilichonse chomwe chimayambitsa kupatuka kuchoka pachiwonetsero, muyenera kuyamba kuchithetsa. Chithandizo chanthawi yake chithandiza kupewa mavuto akulu. Ngati sanachiritsidwe, matenda ashuga amatha kupanga munthu wolumala wopanda thandizo kuchokera mwa munthu nthawi yochepa. Zotsatira zoyipa za matendawa zimatha kukhala chikomokere, matenda oopsa a m'munsi, imfa.
Kupanga Matenda a shuga
Insulin imakhudza njira zonse za metabolic, koma ntchito yake yayikulu ndikukhazikitsidwa kwa kagayidwe kazakudya, kukonza glucose m'mitsempha yamagazi. Chifukwa cha insulin, glucose yochokera m'magazi imabwezedwanso ku minofu ndi minyewa ina, pomwe imagwiritsidwa ntchito, kupatsa mphamvu thupi, kapena kusungidwa ngati glycogen.
Nthawi zambiri, kuchuluka kwa insulin mwa akulu ndi chizindikiro cha matenda osakhazikika mu carbohydrate metabolism. Uku mwina ndi kuyamba kwa matenda ashuga a 2 kapena lingaliro lakelo. Chifukwa cha kusachita masewera olimbitsa thupi, kudya kwambiri kwa carb, kusowa kwa mavitamini ndi fiber, komanso kunenepa kwambiri, kukana insulini kumayamba kukula - kuchepa kwa chidwi cha maselo amthupi kupita ku insulin. Minofu yathu sifunikira mphamvu zochuluka monga momwe imakhalira, ndipo glucose imayamba kudzikundikira m'matumba. Ngati muchepetsa kudya zakudya zamafuta ochulukirapo ndikuwonjezera zochitika panthawiyi, matenda a shuga angathe kupewedwa.
Kuwonjezeka kwamankhwala a insulin ndi kuyesa kwa thupi kuthana ndi insulin. Amawonedwa pa gawo la prediabetes komanso zaka zoyambirira za matenda ashuga. Monga lamulo, pa gawo lino shuga akhoza kukhalabe yabwinobwino kapena kupitirira apo. Pakupita kwa zaka, kapamba amatopa kugwira ntchito mwadzidzidzi, insulini imachepa, kenako imagwera pansi. Pofika pano, wodwalayo ali ndi shuga wambiri, kuti abwezeretse mwanjira yovomerezeka, njira zamankhwala kapena chakudya chofunikira.
Kutsika kwa insulin mwa ana ndi achinyamata nthawi zambiri chizindikiro cha matenda ashuga 1. Zimayambitsidwa ndi kuwonongeka kwa maselo a pancreatic omwe amatulutsa timadzi timeneti. Kuphwanya kumeneku sikugwirizana ndi njira ya moyo, chomwe chimayambitsa kusowa kwa insulini mumtunduwu wa shuga ndi njira za autoimmune. Insulin itangotsala pang'onopang'ono, wodwalayo amafunika chithandizo chamankhwala - jakisoni wa insulin.
Mitengo ya insulin
M'mabotolo, mitengo ya insulin ndi yosiyana kwambiri. Izi ndichifukwa cha njira zingapo pakutsimikiza kwake, pogwiritsa ntchito ma reagents osiyanasiyana opanga. Mu ma labotore omwe amagwiritsa ntchito njira yogwiritsira ntchito immunochemical, mwa akulu, 2.7-10.4 μU / ml nthawi zambiri imawoneka yabwinobwino. Prerequisites: kusanthula kunachitika pamimba yopanda kanthu, kulemera kwa wodwala kumakhala kwabwinobwino kapenanso kupitirira apo (mpaka pa BMI 30).
Mukalandira zotsatira za kusanthula, mfundo zoyenera za labotale inayake zimaperekedwa pagawo la tebulo "Zofunikira". Kuwunikiranso mobwerezabwereza kumachitika bwino pamalo amodzi kapena njira yomweyo.
Zotsatira kuchokera kuma labotale osiyanasiyana sizingatheke kudziwa ngati insulini yanu yachuluka kapena yachepa.
Zikhalidwe za amuna
Mwa amuna, kuchuluka kwa insulini ndikokhazikika kuposa azimayi. Zizindikiro zimangotengera kulemera ndi ukalamba:
- Mukamakula, thupi limafunikira kwambiri insulini. Kuphatikiza apo, minofu ya adipose yowonjezera imayambitsa kutsika kwa kuchuluka kwa insulin receptors, chifukwa chake chidwi cha mahomoni chimachepa.
- Kukaniza insulin kumayamba ndi zaka. Kutumizira kagayidwe kazakudya kumafuna insulin yochulukirapo, shuga ya m'magazi imakwera pang'ono poyerekeza ndi unyamata.
Malingaliro omwe amagwiritsidwa ntchito nthawi zonse amuna amaperekedwa patebulo:
Khalidwe Lodwala | Norm, μU / ml | |
mphindi | max | |
Unyamata, kulemera kwabwinobwino | 2,7 | 10,4 |
Unyamata, kunenepa kwambiri | 2,7 | 24,9 |
Akuluakulu | 6 | 36 |
Malingaliro achikazi
Mwa akazi, kuchuluka kwa insulin kumadaliranso zaka komanso kulemera. Zowonjezera zomwe zimapangitsa kuti insulin iwonjezeke ndi kulumpha kwa mahormone pakapita nthawi yayitali, kugwiritsa ntchito njira yolerera yolerera pakamwa.
Khalidwe Lodwala | Mulingo wa insulin m'mwazi wa mkazi, μU / ml | |
mphindi | max | |
Atsikana achichepere olemera | 2,7 | 10,4 |
1 trimester ya mimba | 2,7 | 10,4 |
2-3 trimester | 6 | 27 |
Akazi olemera kwambiri | 2,7 | 24,9 |
Amayi kuyambira wazaka 60 | 6 | 36 |
M'milungu yoyamba ya kubereka, kufunika kwa insulin kumachepetsedwa pang'ono, kotero kuti kutulutsidwa kwake m'magazi kungachepe. Kuyambira kuyambira pa 2nd trimester, nthawi imodzi ndi kukula kwa mahomoni ena, kaphatikizidwe ka insulin iyenera kukulanso. Ngati kapamba angalimbane ndi ntchitoyo, shuga amakhalanso abwinobwino. Ngati kupanga kwa insulini m'magawo akulu sikutheka, mkaziyo amadwala matenda a shuga. Mu 3 trimester, kukana insulini kumakula ndi 50%, kupanga insulini - pafupifupi katatu. Pambuyo pobadwa, kufunika kwa insulini kumatsika kwambiri, kupanga kwake kumachepa, matenda osokoneza bongo amatha.
Mitundu ya ana
Zochita mu ana nthawi zambiri zimakhala zazikulupo kuposa za akulu. Ngakhale kulemera kwawo kochepa, amafunika mphamvu zambiri. Ophunzira achichepere amafunika mpaka 2600 kcal patsiku, zomwe ndizofanana ndi kufunikira kwa akuluakulu. Chifukwa chake, chizolowezi cha insulin muubwana ndi wamkulu: 2.7-10.4. Mwa achinyamata, kukana insulini ndikwambiri chifukwa cha kuchuluka kwa mahomoni, insulin yambiri imapangidwa. Malingaliro a insulini m'magazi mu achinyamata amakhala ndi kuchuluka kwa 2.7-25 μU / ml.
Ngati mwana ali ndi kulemera kwabwinobwino ndipo samakhala ndi zizindikiro za hypoglycemia, kuwonjezeka pang'ono kwa insulini pamwamba pazowonetsa sikuti chifukwa chodera nkhawa. Mwambiri, amayamba chifukwa cha kukula ndi kusasitsa.
Zotsatira za insulin pa kagayidwe
Hemuloni imalowetsa glucose m'maselo, kupatsa thupi mphamvu yomwe imatulutsidwa mkati mwake. Kuphatikiza apo, imapereka ma amino acid (makamaka valine ndi leucine), potaziyamu, magnesium ndi phosphate ion ku zimakhala.
Insulin imatha kuyambitsa michere yayikulu yomwe imakhudzidwa ndikugwiritsa ntchito shuga pamagulu a glycolysis ndi mapangidwe a glycogen, ndikuchepetsa mapangidwe a shuga m'maselo a chiwindi. Chifukwa cha zovuta zotere, glucose zomwe zimapangidwa kuchokera ku chakudya zimachepetsedwa.
Kwa thupi, insulini ndiye mahomoni ofunikira kwambiri, chifukwa amathandizira kapangidwe ka mapuloteni ndipo amalepheretsa kusweka kwake. Mphamvu ya insulin pa mafuta kagayidwe imalephera mu mawonekedwe a kuchuluka kwa mafuta acids, kusintha kwa glucose kukhala triglycerides mu chiwindi, ndi kuchepa kwa lipid kudya m'magazi.
Mwa anthu athanzi, insulin imasungidwa kuchokera ku zikondamoyo zonse zakunja kwa chakudya - zotsekedwa ndi basal, ndikulimbikitsidwa poyankha glucose yemwe amalowa m'magazi. Nthawi yomweyo, zomwe zimapezeka m'magazi zimachokera ku 3 mpaka 25 mcED / ml. Kuti muwone molondola kuchuluka kwa insulin, kuwunika kotero kumachitika kokha pamimba yopanda kanthu.
Chizindikiro cha thupi lachikazi ndikusintha kwa insulinemia panthawi ya kusinthasintha kwa mahomoni. Chifukwa chake, chizolowezi cha insulin m'magazi a azimayi panthawi yoyembekezera imachokera ku 6 mpaka 28 mcED / ml.
Kusintha kwa insulin kuchokera kwa akazi m'magazi kumatha kuchitika msambo komanso mukamamwa mapiritsi oletsa kubereka.
Kupatula zomwe zimayambitsa kuwerengera zabodza, muyenera kukonzekera kafukufuku pazokhudza insulin yamagazi. Kuti muchite izi, yang'anani izi:
- Kwa tsiku, osapatula mowa, zakudya zamafuta, zolimbitsa thupi.
- Maola 8-10 musanayambe phunziroli simungadye, imwani khofi, tiyi kapena msuzi.
- Patsiku la kusanthula, mutha kumamwa madzi osowa.
- Phunzirolo lisanachitike, simungasute kwa maola awiri.
Zochenjera ndi chizolowezi cha insulin mwa azimayi amsinkhu wobala sichikugwirizana ndi nthawi yakusamba, kotero mutha kuchita kusanthula tsiku lililonse.
Kuchuluka kwa insulin m'mwazi
Kuchulukitsa kwa insulini m'magazi kumakhala ndi vuto lililonse pamatenda a mafuta ndi mtima.Izi ndichifukwa choti gawo lalikulu la timadzi timeneti timatseka lipase, enzyme yomwe imaphwanya triglycerides m'thupi, chifukwa chake, mafuta ambiri amawonjezeka.
Kuphatikiza apo, thupi limakulitsa mapangidwe mamolekyu atsopano a lipid, omwe amachititsa kuti mafuta ochuluka a cholesterol alowe m'magazi ndi mawonekedwe ake pazitseko zamitsempha yamagazi. Kusintha ndi kuchepera kwa lumen kwa mitsempha ndi ma capillaries ang'onoang'ono amawonetsedwa pakuchepa kwa magazi m'matupi. Kusintha kotero ndi chikhalidwe cha atherosulinosis.
Zomwe zimapangitsa kuti insulin iwonjezeke m'magazi zitha kuphatikizidwa ndi kudya kwambiri, kusachita masewera olimbitsa thupi mu shuga, kunenepa kwambiri, komanso mphamvu ya mahomoni a endocrine.
Ngati insulin ikwezedwa, ndiye kuti zotsatirazi zam'thupi zimayambira m'thupi:
- Chiwopsezo cha matenda a mtima, stroko imakulanso.
- Kukula kwa tumor kumatheka.
- Masomphenya akuipiraipira.
- Pali kudzikundikira kwamafuta m'matumbo amkati, mozungulira ziwalo zamkati.
- Kupsinjika kwa magazi kumakwera.
- Mphumu ya bronchial ndi bronchitis ikupita patsogolo.
- Kusabala, kusabereka.
Zomwe zimapangitsa kuti insulini m'mwazi ziwonjezeke zimatha kugwirizanitsidwa ndi kupezeka kwa kukokana kwa minofu m'thupi la mayi uyu. Njira zoterezi zimatchedwa insulin kukana ndipo zimawonetsedwa posankha zochita za insulin. Katemera wa insulin amawonjezedwa kuti athane ndi hyperglycemia.
Clinical Syndrome X ndi kuphatikiza kwa kukokana ndi insulin yodalira shuga, kunenepa kwambiri, kukhumudwa kwa glucose, dyslipidemia, mtundu 2 shuga.
Kutsutsa kwa insulin kumatha kuchitika pakapangidwe ka insulin yolakwika, kuchuluka kwa ma receptor ake, pamlingo wa mayendedwe a shuga m'm cell, komanso panthawi ya kuwonongeka kwa insulin receptors.
Kunenepa kwambiri kumatha kuyambitsa matenda a insulin nthawi zambiri kuposa zifukwa zina.
Momwe mungachepetse misempha yayikulu?
Pofuna kuti zisayambitse kukonzekera kwambiri kwa insulin zida, tikulimbikitsidwa kuti zakudya zazikulu ziyenera kuchepetsedwa katatu patsiku, zokhwasula-khwasula ziyenera kuchitika ndi zinthu zomwe zimakhala ndi insulin index yotsika. Kamodzi pa sabata muyenera kukhala ndi masiku osala kapena kusala pang'ono.
Kukana kwakanthawi kochepa kwa chakudya kumabweretsa ntchito yamafuta ngati gwero lamphamvu, zomwe sizifunikira kutulutsidwa kwa insulin. Njira zopewera izi zitha kuchitika moyang'aniridwa ndi achipatala, monga odwala omwe ali ndi matenda ashuga.
Kuletsedwa kwa zakudya zamagulu omwe amakhala ndi inshuwaransi yayikulu ndikofunikira kwa mtundu wachiwiri wa shuga wokhazikika ndi kuwonjezereka kwa kuchuluka kwa insulin (pakuwunika kosala). Mwa zinthu zambiri, panali zochitika za glycemic ndi insulin index, kupatula mkaka ndi mkaka.
Izi zimatha kukulitsa insulin:
- Confectionery, maswiti.
- Mbatata yophika.
- Zinthu za mkate.
- Mpunga wosendedwa, nthochi.
- Ziphuphu
- Yoghur, mkaka, ayisikilimu.
- Zipatso zokoma.
Pankhaniyi, odwala onse omwe amakonda kwambiri insulin, makamaka mtundu wa shuga wachiwiri, salimbikitsidwa kuphatikiza mafuta amkaka ndi chakudya komanso osawawononga masanawa.
Pazakudya za mapuloteni, njira yabwino kwambiri ndi kuphatikiza mafuta osapakidwa kapena CHIKWANGWANI: nkhuku (nsomba) ndi saladi yovekedwa ndi mafuta a masamba, ndipo zoumba zitha kudyedwa ndi mtedza kapena mapeyala, mbewu za fulakesi, dzungu, mpendadzuwa.
Komanso, zolimbitsa thupi zolimbitsa thupi zimagwira ntchito yofunika kwambiri pakuwonjezera chidwi cha minyewa ya insulin, ndikumachita zolimbitsa thupi pafupipafupi.
Kanemayo munkhaniyi ayankhula mwatsatanetsatane za kuchuluka kwa insulin m'magazi.
Mitundu ya kusanthula
Kuti muzindikire zomwe zili ndi insulin m'matumba, muyenera kudutsa kuwunika kwa "Immunoreactive insulin." Zisonyezo pazolinga za kusanthula ndi:
- Kukayikira kwa chotupa chokhala ndi maselo a pancreatic beta. Pankhaniyi, insulini ikhoza kukhala yokwera kakhumi kuposa momwe imakhalira.
- Kuwunika kwa opaleshoni mankhwala a zotupa zotere.
- Kuzindikira zomwe zimayambitsa hypoglycemia.
- Kuwunika kwa pancreatic ntchito mtundu 2 shuga. Mwazokayikira, kusanthula kumathetsa nkhani yopereka jakisoni wa insulin kapena mankhwala omwe amalimbikitsa kapangidwe ka mahomoni ake.
- Mu shuga wofatsa wambiri komanso prediabetes, kafukufuku atha kutumizidwa kuti athe kuyesa insulin. Mwanjira iyi, imaperekedwa nthawi yomweyo ndi shuga wamagazi (HOMA-IR test).
Pankhani ya shuga wodalira insulin, kuyezetsa kwa insulin sikumagwiritsidwa ntchito, popeza insulin ya insulin silingathe kusiyanitsidwa ndi njira zolembetsera kunja. Poyang'ana ntchito za kapamba, phunziroli "C-peptide m'magazi" limagwiritsidwa ntchito.
Doctor of Medical Science, Mutu wa Institute of Diabetesology - Tatyana Yakovleva
Ndakhala ndikuphunzira matenda a shuga kwa zaka zambiri. Zimakhala zowopsa anthu ambiri akamwalira, ndipo makamaka amakhala olumala chifukwa cha matenda ashuga.
Ndithamangira kunena mbiri yabwino - Endocrinological Research Center ya Russia Academy of Medical Science idatha kupanga mankhwala omwe amachiritsiratu matenda ashuga. Pakadali pano, kugwiritsa ntchito bwino kwa mankhwalawa kuyandikira 98%.
Nkhani ina yabwino: Unduna wa Zaumoyo wateteza kukhazikitsidwa kwa pulogalamu yapadera yomwe imalipira mtengo wa mankhwalawo. Ku Russia, odwala matenda ashuga mpaka Meyi 18 (kuphatikiza) nditha kuipeza - Kwa ma ruble 147 okha!
Kusala insulin
Nthawi zambiri, kuchuluka kwa insulin kumatsimikiziridwa pamimba yopanda kanthu. Malamulo okonzekera kusanthula:
- Kuthamanga kwa ola 8 mpaka mpaka magazi. Mlingo wa insulin mutatha kudya ndiwokwera kwambiri (mpaka 173), chifukwa chake, kulephera kutsatira izi kungapangitse kuti muwoneke kwambiri zotsatira zake, chifukwa chake sanadziwe zolondola.
- Ngati ndi kotheka, kuthetsedwera kwa mankhwala osokoneza bongo ndi zakudya zowonjezera kwa maola 24.
- Kusiyidwa kwa zakudya zochuluka kwambiri zamafuta ndi mowa patsiku lisanathe kusuta.
- Kutseka kwa maphunziro ndi zina zolimbitsa thupi patsiku loti lisinthe.
- Popewa kupsinjika kwa m'maganizo m'mawa komanso m'mawa maphunziro asanafike.
Kupanikizika insulin
Kusanthula uku kumagwiritsidwa ntchito kawirikawiri pakakhala koyenera kuti ayang'anire mayankho a kapamba kuti asinthe shuga. Nthawi zambiri zimachitika nthawi imodzi ndi kuyesa kwa glucose. Gawo 1, shuga ndi insulin amayesedwa mwachangu. Kenako kapamba "amadzaza" ndi shuga (nthawi zambiri njira yake imaperekedwera kumwa). Kuchita mwachizolowezi pamtolo woterewu ndi kuwonjezeka kwa shuga m'magazi ndipo, ndikuchedwa pang'ono, kuwonjezereka kwa insulin, kenako kutsika pang'onopang'ono kuzisonyezo zonse ziwiri. Pambuyo 2 maola, shuga ayenera kukhala 11.1, insulini - mpaka 79. Onetsetsani kuti mwapeza mfundo za insulin posindikiza zotsatira zanu, zimasiyana.
Zotsatira zoyipa za insulin
Ngati insulin ikwezedwa, zovuta zimakhudza machitidwe onse amthupi:
- Malangizo a glucose amakhala spasmodic: poyamba mulingo wake umakhala wokwera kwambiri, koma kutulutsidwa kwa insulin kumachepa kwambiri. Munthu amamva hypoglycemia wofatsa: mantha, ludzu, kulakalaka maswiti. Zakudya zamafuta ochulukitsa zimangokhala zokha, wodwalayo ndi gawo limodzi loyandikira shuga.
- Insulin yayikulu imalimbikitsa kapangidwe ka mafuta, imalepheretsa kusweka kwawo. Munthu akulemera kwambiri.
- Pamodzi ndi kukula kwa minofu yamafuta, lipids yamagazi imakulanso. Minofu ya adipose yomwe ili m'mimba mwa m'mimba imakhala yowopsa kwambiri: triglycerides kuchokera m'matumbo imalowa m'magazi mwachangu.
- Mu chiwindi, cholesterol synthesis imachulukirachulukira, chiopsezo cha atherosulinosis chikukula.
- Insulin yochulukirapo imakhudza zinthu zomwe zimayambitsa magazi, zomwe zimaphatikizana ndi atherosulinosis zimasokoneza thrombosis.
- Kutalika kwa insulin kwambiri kumawonjezera mamvekedwe a mitsempha, kumakhala ndi mitsempha yamagazi, yomwe imayambitsa kuchuluka kwa magazi.
Momwe mungasinthire insulin
Kukula kwa insulin ndi gawo limodzi mwazinthu zovuta kupanga zamatenda a metabolic. Zosintha mu metabolism zimadziunjikira, munthu amakhala mozungulira woipa: kulemera - kukula kwa insulini - kulakalaka kwambiri - kupanga mafuta atsopano. Ndizotheka kuthana ndi izi pokhapokha pakusintha kwamakadinala munjira ya moyo.
Choyamba, zakudya zopatsa mphamvu zopatsa mphamvu zamafuta zimalembedwa. Mashuga onse othamanga amatsikira oletsedwa kwambiri, chifukwa ndi omwe amachititsa kwambiri insulin. Kuchuluka kwa zovuta zamagalimoto ochulukirapo mumenyu ndizochepa 20-25% ya kuchuluka kwa michere yonse. Popewa matenda a atherosulinosis, mafuta amanyama amachotsedwa muzakudya.
Kubwezeretsa minofu ya m'magazi, muyenera kuwonjezera katundu pa iwo. Zochita zamtundu uliwonse ndizothandiza. Maphunziro a Cardio ndi ovomerezeka kwakanthawi: kupopera shuga kumawonjezereka ndi masiku awiri, motero amawaika mu ndandanda yophunzitsidwa katatu pa sabata. Kuchita zolimbitsa thupi kumalimbikitsa kukula kwa minofu - wogula wamkulu wa shuga. Njira yabwino yodziwira matenda a shuga ndikusinthana kwa mitundu yonse iwiri ya katundu.
Onetsetsani kuti mwaphunzira! Kodi mukuganiza kuti kuyamwa kwa mapiritsi ndi insulini kwa nthawi yonse yokhayo ndi njira yokhayo yothanirana ndi shuga? Sichowona! Mutha kutsimikizira izi nokha ndikuyamba kuzigwiritsa ntchito. werengani zambiri >>