• Kuyimitsidwa kwa ma s / c kukongoletsa kwamtundu woyera, womwe umatuluka, ndikupanga zoyera komanso zowoneka bwino, zopanda utoto kapena zowoneka bwino kwambiri, mpweya woterewu umatha kusunthika modekha. Kuyimitsidwa kwa ma s / c kukongoletsa kwamtundu woyera, womwe umatuluka, ndikupanga zoyera komanso zowoneka bwino, zopanda utoto kapena zowoneka bwino kwambiri, mpweya woterewu umatha kusunthika modekha. Kuyimitsidwa kwa ma s / c kukongoletsa kwamtundu woyera, womwe umatuluka, ndikupanga zoyera komanso zowoneka bwino, zopanda utoto kapena zowoneka bwino kwambiri, mpweya woterewu umatha kusunthika modekha.

Zotsatira za pharmacological

• 1 ml ya insulin ya anthu 100 IU ndi kuyimitsidwa kwamitundu iwiri kapena kusakaniza: sungunuka wa insulin ya anthu 30% kuyimitsidwa kwa isophan insulin 70% Othandizira: distill m-cresol (1.6 mg / ml), glycerol, phenol (0.65 mg / ml), protamine sulfate , sodium phosphate dibasic, zinc oxide, madzi d / ndi, hydrochloric acid, sodium hydroxide. 1 ml ya insulin ya anthu 100 IU ndi kuyimitsidwa kwamitundu iwiri kapena kusakaniza kwa: soluble human insulin solution 30% yaumunthu isofan insulin 70% Excipients: metacresol, glycerol (glycerin), phenol, protamine sulfate, sodium hydrogen phosphate, zinc oxide, madzi d / ndi. , hydrochloric acid (10% yankho) ndi / kapena sodium hydroxide (10% yankho) kuti apange gawo lofunikira la pH. insulin ya anthu 100 IU ndi kuyimitsidwa kwamitundu iwiri kapena kusakaniza kwa: madzi osungunuka aanthu 30% kuyimitsidwa kwa isophane insulin 70% Othandizira: distill m-cresol (1.6 mg / ml), glycerol, phenol (0.65 mg / ml), protamine sulfate, sodium dibasic phosphate, zinc oxide, madzi d / ndi, hydrochloric acid, sodium hydroxide.

Humulin M3 mavuto

• Zotsatira zoyipa zomwe zimakhudzana ndi zotsatira zazikulu za mankhwalawa: hypoglycemia. Hypoglycemia kwambiri ikhoza kuyambitsa kusokonezeka kwa chikumbumtima ndipo (mwapadera) kufa. Thupi lawo siligwirizana: zimachitika matupi awo sagwirizana - hyperemia, kutupa kapena kuyunkhira pamalo a jekeseni (nthawi zambiri amayima patadutsa masiku angapo mpaka masabata angapo), kayendedwe ka ziwalo (zimachitika kawirikawiri, koma zimakhala zowopsa) - kuyamwa kambiri, kufupika, kupuma pang'ono , kuchepa kwa magazi, kuchuluka kwa mtima, kuchuluka thukuta. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo. Zina: mwayi wokhala ndi lipodystrophy ndizochepa.

Humulin insulin yochizira matenda ashuga mwa akulu, ana ndi pakati. Humulin NPH zotsutsana. Malamulo ogwiritsira ntchito

Mankhwala a antidiabetesic Humulin NPH amakhala ndi insulin-isophan, yomwe imakhala ndi nthawi yayitali. Amapangidwira kuti azigwiritsa ntchito mosalekeza kuti magazi azikhala ndi shuga m'magazi wamba. Ipezeka ngati kuyimitsidwa kwa kayendetsedwe ka ma subcutaneous mu Mbale ku United States, Eli Lilly & Company. Ndipo kampani yaku France ya Lilly France imatulutsa insulin Humulin NPH mwanjira yamakokotedwe okhala ndi cholembera. Mankhwala ali ndi mawonekedwe a kuyimitsidwa kwamtambo kapena kwamtambo.

Mphamvu ya pharmacological ndi kuchepa kwa shuga m'magazi chifukwa chakuwonjezera kwa maselo ndi minyewa pogwiritsa ntchito Humulin NPH. Mu shuga mellitus, kupanga kwa pancreatic insulin timadzi kumachepetsedwa, komwe kumafuna chithandizo chamankhwala cha mahomoni.Mankhwala amalimbikitsa kugwiritsidwa ntchito kwa glucose ndi maselo omwe amafunikira zakudya. Insulin imalumikizana ndi ma receptors apadera pamaselo a maselo, omwe amachititsa njira zingapo, zomwe zimaphatikizapo, makamaka, kupanga hexokinase, pyruvate kinase, glycogen synthetase. Kutumiza kwa glucose kumisempha kuchokera m'magazi kumachuluka, komwe kumakhala kocheperako.

Zotsatira zoyipa

Zotsatira zoyipa zomwe zimakhudzana ndi kagayidwe kazachilengedwe: michere ya hypoglycemic (pallor, kutuluka thukuta, palpitations, mavuto ogona, kugwedezeka).

Thupi lawo siligwirizana: kawirikawiri - zotupa pakhungu, osowa kwambiri - angioedema.

Zomwe zimachitika mdera: kawirikawiri - hyperemia ndi kuyabwa pamankhwala a jekeseni wa mankhwalawa, ndikugwiritsa ntchito nthawi yayitali - lipodystrophy pamalo a jekeseni.

Kuchita

Zotsatira za hypoglycemic za insulin zimapangidwira ndi ma inhibitors a MAO, osagwiritsa ntchito beta-blockers, sulfonamides, anabolic steroids, tetracyclines, clofibrate, cyclophosphamide, fenfluramine, ndi kukonzekera komwe kumakhala ndi ethanol.

Kulera kwapakamwa, glucocorticoids, mahomoni a chithokomiro, thiazide diuretics, heparin, kukonzekera kwa lifiyamu, antidepressants tricyclic amachepetsa mphamvu ya insulin.

Mothandizidwa ndi reserpine ndi salicylates, onse ofooketsa ndikuwonjezera zochita za insulin ndizotheka.

Beta-blockers, clonidine, reserpine amatha kuphimba mawonetseredwe a zizindikiro za hypoglycemia.

Ethanol, mankhwala ophera majakisoni amatha kuchepetsa zochita za insulin.

Momwe mungatenge, njira ya makonzedwe ndi kumwa

Dokotala amakhazikitsa mlingo payekhapayekha, kutengera mlingo wa glycemia.

Mankhwalawa amayenera kuperekedwa mosavuta, mwina kudzera m'mitsempha. Intravenous makonzedwe a Humulin M3 amatsutsana!

Pang'onopang'ono, mankhwalawa amaperekedwa paphewa, ntchafu, matako kapena pamimba. Tsamba la jakisoni liyenera kusinthidwa kuti malo omwewo asagwiritsidwerenso kuposa nthawi 1 / mwezi.

Pakuperekedwa mosamala mosamala, muyenera kusamala kuti mupewe magazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Odwala ayenera kuphunzitsidwa bwino kugwiritsa ntchito zida za insulin.

Malamulo okonzekera ndi kuyendetsa mankhwalawa

Makatoni ndi mbale za Humulin M3 zizikulungika pakati pa manja nthawi 10 musanagwiritse ntchito, kugwedezeka, kutembenukira ku 180 ° komanso maulendo 10 kuti muthetsenso insulin mpaka itakhala yunifolomu kapena mkaka wofanana. Gwedezani mwamphamvu, monga izi zimatha kuyambitsa foam, zomwe zingasokoneze mlingo woyenera.

Makatoni ndi mbale ziyenera kufufuzidwa mosamala. Osagwiritsa ntchito insulini ngati ili ndi flakes mutasakaniza, ngati ma cell oyera olimba amatsatira pansi kapena makoma a vial, ndikupanga mawonekedwe a frosty.

Chipangizo cha ma cartridge sichimalola kusakanikirana ndi zomwe zili ndi insulini zina mwachindunji mu cartridge lokha. Makatoniwo sanapangidwe kuti adzazitsidwe.

Zomwe zili mu vial ziyenera kudzazidwa ndi syringe ya insulin yolingana ndi kuchuluka kwa insulini yoyendetsedwa, ndipo mlingo woyenera wa insulin uyenera kuperekedwa monga adalangizidwa ndi adokotala.

Mukamagwiritsa ntchito makatoni, tsatirani malangizo opanga opangira makatoni komanso kupaka singano. Mankhwalawa amayenera kuperekedwa molingana ndi malangizo a wopanga a cholembera.

Kugwiritsa ntchito kachulukidwe kakunja ka singano, mutangoyikapo, vula singano ndikuwononga mosavomerezeka. Kuchotsa singano mutangolowa jakisoni kumathandizira kusokonekera, kupewa kutayikira, kutsekeka kwa mpweya ndi kuboweka kwa singano. Kenako ikani chophimba chija.

Singano sayenera kugwiritsidwanso ntchito. Ma singano ndi ma cholembera a syringe sayenera kugwiritsidwa ntchito ndi ena. Makatoni ndi mbale zimagwiritsidwa ntchito mpaka zitakhala zopanda kanthu, pambuyo pake zimatayidwa.

Bongo

Zizindikiro: hypoglycemia, limodzi ndi kupha mphamvu, kuchuluka thukuta, tachycardia, kufooka kwa khungu, mutu, kunjenjemera, kusanza, chisokonezo.

Nthawi zina, mwachitsanzo, pakhale nthawi yayitali kapena kuwunika kwambiri matenda a shuga, Zizindikiro za hypoglycemia zimatha kusintha.

Chithandizo: Hypoglycemia nthawi zambiri imatha kuyimitsidwa pakumeza shuga (dextrose) kapena shuga. Kusintha kwa mlingo wa insulin, zakudya, kapena zolimbitsa thupi kungafunike.

Malangizo a hypoglycemia wolimbitsa amatha kuchitika pogwiritsa ntchito minyewa kapena subcutaneous makukidwe a glucagon, otsatiridwa ndi kumeza chakudya.

Zambiri za hypoglycemia, limodzi ndi chikomokere, kukomoka kapena kuchepa kwa mitsempha, zimayimitsidwa ndi kutsekeka kapena kutsekeka kwa glucagon kapena kulowetsedwa kwa njira yokhazikika ya glucose (dextrose). Pambuyo pozindikira, wodwalayo ayenera kupatsidwa chakudya chamagulu owonjezera chakudya kuti asayambenso kukonzekera hypoglycemia.

Malangizo apadera

Kusintha kuchokera ku mtundu wina wa insulin kupita ku wina kuyenera kuchitika mothandizidwa ndi misempha yamagazi.

Pakakhala vuto la insulin yochulukirapo, ngati wodwalayo amadziwa, ndikofunikira kupatsa shuga pakamwa, chifukwa cha kutaya kwa chikumbumtima cha shuga iv kapena glucagon sc, im kapena iv.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe kazinthu

Mukasamutsa wodwala ku insulin iyi, kuchepa kwakanthawi kwa ma psychomotor reaction kumatheka.

Humulin M3 ndi mankhwala omwe amapanganso insulin. Ndi kuyimitsidwa kawiri kwa jakisoni (30% Humulin Regular ndi 70% Humulin NPH). Chochita chachikulu cha insulin ndi kuphatikiza shuga kagayidwe. Kuphatikiza apo, ili ndi anabolic zotsatira. Mu minofu ndi minyewa ina (kupatula ubongo), insulin imayendetsa mofulumira intracellular ya glucose ndi amino acid, imathandizira protein anabolism. Insulin imalimbikitsa kutembenuka kwa glucose kukhala chiwindi cha glycogen, kumalepheretsa gluconeogeneis ndikuthandizira kusintha kwa glucose owonjezera kukhala mafuta.

Humulin M3 ndicholinga cha insulin. Kukhazikika kwa mankhwalawa ndi mphindi 30 pambuyo pa kuperekedwa, mphamvu yayikulu imakhala pakati pa 1 ndi maola 8.5, kutalika kwa maola 14 - 15 maola. Kusiyana kwamwini pantchito ya insulin kumadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi ndi ena.

Chithandizo cha odwala matenda a shuga a mellitus, omwe amawonetsa insulin mankhwala, chithandizo cha odwala omwe apezeka ndi matenda osokoneza bongo a mellitus, pakati pa odwala omwe ali ndi matenda a shuga 2.

Mlingo wa Humulin M3 umatsimikiziridwa ndi dokotala aliyense payekha, kutengera mlingo wa glycemia. Mankhwalawa amayenera kuperekedwa mosavuta. Intramuscular management ndiyothekanso. Intravenous makonzedwe a Humulin NPH amatsutsana. Jakisoni wotsekemera amayenera kuperekedwa kwa mapewa, m'chiuno, matako kapena pamimba. Masamba a jakisoni ayenera kusinthidwa kuti malo omwewo sawagwiritsanso ntchito mwina kamodzi pamwezi. Ndi subulinaneous ya insulin, chisamaliro chimayenera kumwedwa kuti musalowe m'mitsempha yamagazi pakubaya. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Odwala ayenera kuphunzitsidwa bwino kugwiritsa ntchito zida za insulin. Humulin M3 ndi osakaniza opangidwa kale ndi zina za Humulin Regular ndi Humulin NPH, okonzedwa kuti apewe kufunika kosakaniza insulin yokonzekera ndi odwala omwe. Ndondomeko ya insulin makonzedwe ali payekha.

Bongo insulin imayambitsa hypoglycemia, limodzi ndi zizindikiro izi: ulesi, thukuta kwambiri, tachycardia, pallor pakhungu, kupweteka mutu, kunjenjemera, kusanza, chisokonezo.Nthawi zina, mwachitsanzo, pakhale nthawi yayitali kapena kuwunika kwambiri matenda ashuga, Zizindikiro zakutsogolo kwa hypoglycemia zimatha kusintha. Hypoglycemia wofatsa nthawi zambiri imatha kuimitsidwa mwa kumeza shuga kapena shuga. Kusintha kwa mlingo wa insulin, zakudya, kapena zolimbitsa thupi kungafunike. Malangizo a hypoglycemia wolimbitsa amatha kuchitika pogwiritsa ntchito minyewa kapena subcutaneous makukidwe a glucagon, otsatiridwa ndi kumeza chakudya. Miyezo yambiri ya hypoglycemia, yokhala ndi chikomokere, kukomoka kapena kuchepa kwa mitsempha, imayimitsidwa ndi kutsekeka / kupindika kwa glugagon kapena kulowetsedwa kwa njira yokhazikika ya shuga. Pambuyo pozindikira, wodwalayo ayenera kupatsidwa chakudya chamagulu owonjezera chakudya kuti asayambenso kukonzekera hypoglycemia.

Kukonzekera mlingo. Musanagwiritse ntchito, makatiriji a Humulin M3 amayenera kukukhidwira pakati pama manja khumi ndikugwedezeka, ndikusintha 180ºº, komanso maulendo khumi kuti muyambenso insulin mpaka iwoneke ngati mawonekedwe amitambo kapena mkaka. Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera. Makatoni amayenera kufufuzidwa mosamala. Musagwiritse ntchito insulini ngati ili ndi mapokoso mukasakaniza. Chipangizo cha Humulin cartridges sichimalola kusakanikirana ndi zomwe zili ndi insulini zina mwachindunji cha katiriji palokha. Makatoniwo sanapangidwe kuti adzazitsidwe. Tsatirani malangizo a wopanga kuti muthetsanso katoni ndikuyika singano.

Dose Administration Sambani m'manja, sankhani malo opaka jakisoni, pukutani khungu ndi swab thonje lomwe litamizidwa mu mowa, ndikuchotsa kapu yakunja ndi singano. Sinthani khungu ndikupanga khola la pakhungu, ikani singano m'mafuta ocheperako mogwirizana ndi malangizo a dokotala, jekeseni insulin mogwirizana ndi malangizo a wopanga a cholembera. Chotsani singano pakhungu mwachindunji ndikumakankhira pamalowo jekeseni kwa masekondi angapo, osasokoneza tsamba la jakisoni. Kugwiritsa ntchito kachulukidwe kakunja ka singano, mutangoyikapo, vula singano ndikuwononga mosavomerezeka. Kuchotsa singano mutangolowa jakisoni kumathandizira kusokonekera, kupewa komanso kutsekeka kwa mpweya, komanso kutheka kwa singano. Ikani kapu pachigoba.

Singano sayenera kugwiritsidwanso ntchito. Singano ayenera kutayidwa moyenera. Singano ndi zolembera siziyenera kugwiritsidwa ntchito ndi ena. Gwiritsani ntchito makatoni mpaka alibe, pambuyo pake azitha.

Lipodystrophy, kukana, kuchuluka kwa chidwi ndi insulin ndizotsatira zoyipa zomwe zimagwiritsidwa ntchito ndikugwiritsa ntchito insulin ya nyama. Kuwonongeka kwa zotsatira zoyipa ndi kukhazikitsidwa kwa Humulin M3 ndikocheperako.

Zotsatira zoyipa zomwe zimakhudzana ndi zotsatira zazikulu za mankhwalawo.

Hypoglycemia ndi zotsatira zoyipa kwambiri zomwe zimachitika ndikukhazikitsa insulin, kuphatikizapo Humulin M3. Hypoglycemia yamphamvu imatha kutha kwa chikumbumtima ndipo, mwapadera, amafa.

Odwala amatha kukumana ndi kwanuko thupi lawo siligwirizana mwanjira yofiyira, kutupa, kapena kuyunkhira pamalo a jekeseni. Izi zimachitika pakatha masiku angapo mpaka milungu ingapo. Nthawi zina, izi zimachitika chifukwa cha zifukwa zosakhudzana ndi insulin, mwachitsanzo, mkwiyo pakhungu ndi wothandizira kuyeretsa kapena jakisoni wosayenera. Zotsatira zoyipa zamagetsi zomwe zimachitika chifukwa cha insulin zimachitika kangapo, koma zimakhala zazikulu kwambiri. Amatha kuwonetsedwa ndi kuyabwa kwakukulu, kupuma movutikira, kufupika, kuchepa kwa magazi, kuchuluka kwa mtima, komanso thukuta kwambiri. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo.Nthawi zina mankhwalawa amakumana ndi Humulin M3, chithandizo chofunikira chimafunikira. Mungafunike kusintha kwa insulin, kapena kutsimikiza mtima.

Hypoglycemia, hypersensitivity kupita ku insulin kapena chimodzi mwazinthu za mankhwala.

Pakati pathupi, ndikofunikira kuti pakhale chitetezo chabwino kwa odwala omwe amalandila insulin (omwe amadalira insulin kapena matenda a shuga). Kufunikira kwa insulin nthawi zambiri kumacheperanso nthawi yoyambirira ndikuwonjezeka panthawi yachiwiri komanso yachitatu. Odwala omwe ali ndi matenda ashuga amalangizidwa kuti adziwitse dokotala za zakutsogolo kapena kukonzekera pakati. Odwala omwe ali ndi matenda a shuga mellitus panthawi yoyamwitsa, pangafunikire kusintha mlingo wa insulin, zakudya, kapena zonse ziwiri.

Kusamutsa wodwala kupita ku mtundu wina kapena kukonzekera kwa insulini ndi dzina lina lamalonda kuyenera kuchitika moyang'aniridwa ndi achipatala. Zosintha mu zochitika za insulin, monga (mwachitsanzo, pafupipafupi, NPH, L, ndi zina), mitundu (nkhumba, insulin ya anthu, analogue ya insulin) kapena njira yopanga (kuyambiranso DNA kapena insulini yachikhalidwe) kungafune kusintha kwa mlingo. Kwa odwala ena, kusintha kwa mlingo kumakhala kofunikira pakusintha kuchokera ku insulin yochokera ku nyama kupita ku insulin ya anthu. Izi zitha kuchitika kale pakukonzekera kwa insulin yaumunthu kapena pang'onopang'ono pakatha milungu ingapo kapena miyezi kuchokera kusamutsidwa. Zizindikiro - zotsogola za hypoglycemia pa nthawi ya insulin yaumwini mwa odwala ena sitha kutchulidwa kapena kusiyanasiyana ndi zomwe zimawonedwa munthawi ya insulin ya nyama. Ndi kusintha kwa matenda a shuga m'magazi, mwachitsanzo, chifukwa cha inshuwaransi yamankhwala, zonse kapena zina mwazizindikirozo zimatha - owonetseratu a hypoglycemia, omwe odwala amafunikira kudziwa. Zizindikiro - zotsogola za hypoglycemia zingasinthe kapena kusalankhula pang'ono ndi njira yayitali ya matenda a shuga, matenda ashuga a m'mimba kapena chithandizo cha mankhwala monga beta-blockers. Kufunika kwa inulin kumatha kuchepa ndi kusakwanira kwa adrenal gland, pituitary kapena chithokomiro, ndi kulephera kwa impso kapena chiwindi. Ndi matenda ena kapena kupsinjika kwamalingaliro, kufunikira kwa insulin kungakulitse. Kuwongolera mlingo wa insulin kungafunikenso ndi kuwonjezeka kwa zochitika zolimbitsa thupi kapena kusintha kwa zakudya zomwe mumakonda.

Pa hypoglycemia, wodwalayo amatha kufooketsa chidwi cha anthu ndikuchepetsa kuthamanga kwa zochitika zama psychomotor. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa amafunikira makamaka (mwachitsanzo, kuyendetsa galimoto kapena makina ogwiritsa ntchito). Odwala ayenera kulangizidwa kuti azisamala kuti asamayendetse hypoglycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofowoka kapena zosapezekapo - zotsogola za hypoglycemia kapena kukula pafupipafupi kwa hypoglycemia. Zikatero, adotolo amayenera kuwunika momwe wodwala angayendetsere galimoto.

Mphamvu ya hypoglycemic ya Humulin M3 yafupika: kulera kwapakamwa, corticosteroids, kukonzekera kwa mahomoni a chithokomiro, thiazide diuretics, diazoxide, antidepressants tricyclic. Mphamvu ya hypoglycemic ya Humulin M3 imalimbikitsidwa ndi: mankhwala a hypoglycemic mankhwala, salicylates (mwachitsanzo, aspirin), sulfonamides, ma inhibitors a MAO, beta-blockers, ethanol ndi ethanol okhala ndi mankhwala. Beta-blockers, clonidine, reserpine amatha kuphimba mawonetseredwe a zizindikiro za hypoglycemia.

1 ml ya kuyimitsidwa kuli ndi insulin biphasic genetic engineering 100 IU.

Mlingo ndi makonzedwe:

Mlingo umatsimikiziridwa payekha kutengera mulingo wa glycemia.

Mankhwala ayenera kuperekedwa sc, mwina / m kuyambitsa. Mu / pakubweretsa Humulin M3 ndi yotsutsana!

Mankhwala a SC amaperekedwa ku dzanja lamanja, ntchafu, matako kapena pamimba. Tsamba la jakisoni liyenera kusinthidwa kuti malo omwewo asagwiritsidwerenso nthawi 1 mwezi uliwonse.

Mukamayambitsa mawuwo, chisamaliro chikuyenera kuyambidwa kuti musalowe mumtsempha wamagazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Odwala ayenera kuphunzitsidwa bwino kugwiritsa ntchito zida za insulin.

Asanagwiritse ntchito, vulin ya Humulin M3 iyenera kukunkhunidwa pakati pa manja nthawi 10 ndikugwedezeka, ndikusintha 180 ° nthawi 10 kuti isungenso insulin mpaka itakhala yunifolomu yamadzi kapena mkaka. Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera.

Mbale zikuyenera kupendedwa mosamala. Osagwiritsa ntchito insulini ngati ili ndi flakes mutasakaniza, ngati ma cell oyera olimba amatsatira pansi kapena makoma a vial, ndikupanga mawonekedwe a frosty.

Zomwe zili mu vial ziyenera kudzazidwa ndi syringe ya insulin yolingana ndi kuchuluka kwa insulini yoyendetsedwa, ndipo mlingo woyenera wa insulin uyenera kuperekedwa monga adalangizidwa ndi adokotala.

Malangizo apadera:

Kusamutsa wodwala kupita ku mtundu wina wa insulin kapena kukonzekera kwa insulin ndi dzina lina lamalonda kuyenera kuchitika moyang'aniridwa ndi achipatala. Zosintha mu zochitika za insulin, mtundu wake (mwachizolowezi, NPH), mitundu (porcine, insulin yaumunthu, analogue ya insulin) kapena njira yopanga (DNA recombinant insulin kapena insulini yachikhalidwe) ingafune kusintha kwa mlingo.

Kufunika kwa kusintha kwa mankhwalawa kungafunike kale pokhazikitsidwa ndi insulin yokonzekera pambuyo pokonzekera insulin ya nyama kapena pang'onopang'ono milungu ingapo kapena miyezi ingapo atasamutsidwa.

Kukopa pa kuyendetsa magalimoto ndi kayendedwe ka kayendedwe: panthawi ya hypoglycemia, wodwala amatha kufooketsa chidwi cha chidwi ndikuchepetsa kuthamanga kwa zochitika zama psychomotor. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa ndi ofunika kwambiri.

Odwala ayenera kulangizidwa kuti azisamala kuti asamayendetse hypoglycemia poyendetsa. Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofatsa kapena zosapezekapo zizindikiro za hypoglycemia kapena kukula pafupipafupi kwa hypoglycemia. Zikatero, adotolo amayenera kuwunika momwe wodwala angayendetsere galimoto.

Malo osungira:

Mankhwalawa amayenera kusungidwa mufiriji kutentha kwa 2 ° mpaka 8 ° C, kupewa kuzizira, kuteteza ku kuyatsidwa mwachindunji. Moyo wa alumali ndi zaka 2.

Mankhwala omwe amagwiritsidwa ntchito mu vial kapena katiriji amayenera kusungidwa kutentha kwambiri (15 ° mpaka 25 ° C) osaposa masiku 28.

Humulin NPH ndi mankhwala ena a gululi amapanga mankhwala omwe amagwiritsidwa ntchito pochiritsa anthu omwe ali ndi matenda ashuga. Mankhwala ali ndi katundu wachilengedwe wochepetsa shuga, popeza amapangidwa pamaziko a insulin yaumunthu. Cholinga chachikulu cha zinthu zopangidwa mwaluso ndi kuchepetsa kuchuluka kwa shuga m'magazi ndikulowetsa mu minofu ndikuyiphatikiza ndi zochita za maselo.

Humulin ndi chiyani?

Masiku ano, mawu akuti Humulin amatha kuwoneka mu mayina a mankhwala angapo omwe adapangidwa kuti achepetse shuga ya magazi - Humulin NPH, MoH, pafupipafupi komanso Ultralent.

Kusiyana kwa njira zopangira mankhwalawa kumapereka mawonekedwe aliwonse ochepetsa shuga ndi zomwe ali nazo. Izi zimazindikiridwa popereka mankhwala kwa anthu odwala matenda ashuga.Kuphatikiza pa insulini (gawo lalikulu, loyesedwa mu IU), mankhwala ali ndi zotuluka, monga madzi osabala, ma protein, carbolic acid, metacresol, zinc oxide, sodium hydroxide, etc.

Horoni ya pancreatic imayikidwa m'makalata, mbale, ndi zolembera. Malangizo omwe aphatikizidwa amadziwitsa za zomwe amagwiritsidwa ntchito ngati mankhwala a anthu. Musanagwiritse ntchito, makatoni ndi mbale siziyenera kugwedezeka mwamphamvu; zonse zofunikira kuti madzi ayambitsenso bwino ndikuzigwetsa pakati pa manja. Choyenera kwambiri chogwiritsidwa ntchito ndi odwala matenda ashuga ndi cholembera.

Kugwiritsa ntchito mankhwala omwe atchulidwa kumathandizira kuti zitheke kupeza chithandizo chokwanira kwa odwala omwe ali ndi matenda ashuga, chifukwa amathandizira kuti pakhale kuperewera kwathunthu komanso kuperewera kwa mphamvu ya amkati amkati. Fotokozerani Himulin (mlingo, regimen) ayenera kukhala wa endocrinologist. M'tsogolo, ngati pakufunika kutero, dokotala yemwe akukonzekera akhoza kuwongolera njira yochizira.

Mu matenda a shuga a mtundu woyamba, insulin imaperekedwa kwa munthu moyo wonse. Ndi zovuta za mtundu wa 2 shuga, zomwe zimayendera limodzi ndi matenda amtundu wa khansa, chithandizo chimapangidwa kuchokera kumagulu osiyanasiyana. Ndikofunika kukumbukira kuti ndi matenda omwe amafunikira kukhazikitsa mahomoni opanga thupi m'thupi, simungakane mankhwala a insulini, apo ayi mavuto akulu sangathe kupewedwa.

Mtengo wa mankhwalawa gulu lama pharmacological zimatengera nthawi yochitapo ndi mtundu wa ma CD. Mtengo wowerengeka m'mabotolo umayambira ku ma ruble 500., mtengo wake m'matotolo - kuchokera ku ma ruble 1000., M'mapensulo a syringe ndi osachepera 1500 rubles.

Kuti mudziwe mlingo ndi nthawi ya kumwa mankhwalawa, muyenera kulumikizana ndi endocrinologist

Zonse zimatengera zosiyanasiyana

Mitundu ya ndalama ndi momwe thupi limakhudzira zikufotokozedwa pansipa.

Mankhwalawa amapangidwa pogwiritsa ntchito ukadaulo wama DNA ndipo amakhala ndi nthawi yayitali. Cholinga chachikulu cha mankhwalawa ndikukhazikitsa kagayidwe ka glucose. Imathandizira kuti muchepetse kusweka kwa mapuloteni ndipo imakhudzanso minofu ya thupi. Humulin NPH imawonjezera ntchito ya ma enzyme omwe amalimbikitsa mapangidwe a glycogen mu minofu minofu. Zimawonjezera kuchuluka kwamafuta acid, zimakhudza kuchuluka kwa glycerol, zimathandizira kupanga mapuloteni komanso zimalimbikitsa kumwa ma aminocarboxylic acid mwa maselo amisempha.

Ma Analogs omwe amachepetsa shuga la magazi ndi:

1. Actrafan NM.
2. Diafan ChSP.
3. Wofukiza N.
4. Protafan NM.
5. Humodar B.

Pambuyo jekeseni, yankho limayamba kugwira ntchito pambuyo pa ola limodzi, mphamvu zonse zimachitika mkati mwa maola 2-8, chinthucho chimakhalabe chogwira ntchito kwa maola 18-20. Nthawi yakukonzekera kwa mahomoni kutengera mlingo womwe wagwiritsidwa ntchito, tsamba la jakisoni, ndi zochita za anthu.

Humulin NPH akuwonetsedwa kuti agwiritse ntchito:

1. Matenda a shuga omwe ali ndi insulin.
2. Woyamba anapeza matenda a shuga.
3. Amayi oyembekezera omwe ali ndi matenda osokoneza bongo omwe amadalira insulin.

Malangizowo akuti mankhwalawa saikidwa kwa anthu omwe ali ndi vuto la hypoglycemia, lomwe limadziwika ndi kutsika kwa magazi m'munsi mwa 3.5 mmol / L, m'magazi otumphukira - 3,3 mmol / L, mwa odwala omwe ali ndi hypersensitivity kwa zigawo zina za mankhwala.
Zotsatira zoyipa zomwe zingachitike mutagwiritsa ntchito mankhwalawa nthawi zambiri zimawonetsedwa:

1. Hypoglycemia.
2. Kuwonongeka kwamafuta.
3. Zokhudza zonse komanso zam'deralo.

Ponena za mankhwala osokoneza bongo a mankhwalawa, palibe zizindikiro zenizeni za kumwa mopitirira muyeso. Zizindikiro zazikuluzikulu zimadziwika ngati chiyambi cha hypoglycemia. Vutoli limaphatikizidwa ndi kupweteka kwamutu, tachycardia, thukuta lotupa komanso khungu. Popewa zovuta zotere, dokotala amasankha kuchuluka kwa wodwala aliyense payekhapayekha, poganizira kuchuluka kwa glycemia.

Ndi mankhwala osokoneza bongo ambiri, hypoglycemia ingachitike.

Humulin M3, monga mankhwala am'mbuyomu, adapangidwa nthawi yayitali.Imadziwika mu mawonekedwe a kuyimitsidwa kwamitundu iwiri, makatoni am'magalasi amakhala ndi insulin humulin pafupipafupi (30%) ndi humulin-nph (70%). Cholinga chachikulu cha Humulin Mz ndikuwongolera kagayidwe ka glucose.

Mankhwalawa amathandizira kupanga minofu, imatulutsa shuga ndi aminocarboxylic acid m'maselo a minofu ndi minyewa ina kupatula ubongo. Humulin M3 imathandizira mu minofu ya chiwindi kusanduliza glucose kukhala glycogen, imalepheretsa gluconeogeneis ndikusintha glucose owonjezereka kukhala subcutaneous ndi visceral mafuta.

Zotsatira za mankhwalawa ndi:

1. Protafan NM.
2. Farmasulin.
3. Actrapid Flekspen.
4. Lantus Optiset.

Pambuyo pakubaya, Humulin M3 imayamba kugwira ntchito pambuyo pa mphindi 30-60, mphamvu kwambiri imapezeka mkati mwa maola 2-12, nthawi ya insulini ndi maola 24. Zomwe zimakhudza kuchuluka kwa ntchito ya Humulin m3 zimagwirizanitsidwa ndi tsamba losankhidwa ndi jekeseni, ndi zochitika zolimbitsa thupi za munthu ndi chakudya chake.

1. Anthu omwe ali ndi matenda ashuga omwe amafunikira chithandizo cha insulin.
2. Amayi oyembekezera omwe ali ndi matenda ashuga.

Neutral insulini zothetsera zimaphatikizidwa pakupezeka hypoglycemia ndi hypersensitivity pazomwe zimapangidwira. Mankhwala a insulin ayenera kuchitika moyang'aniridwa ndi dokotala, omwe amachotsa kukula ndi kusokonezeka kwa hypoglycemia, komwe kumatha, chifukwa chabwino kwambiri, chomwe chimayambitsa kukhumudwa komanso kutaya chikumbumtima, choyipa kwambiri - kumayambiriro kwa imfa.

Pa mankhwala a insulini, odwala amatha kudwala matendawa, omwe nthawi zambiri amakhala akuwukidwa, kusungunuka, kapena kutupira khungu pakhungu. Khungu limakhala yofanana pakadutsa masiku 1-2, pamavuto ena pamafunika masabata angapo. Nthawi zina zizindikirozi ndi chizindikiro cha jakisoni wolakwika.

Kuchepa kwachilengedwe kumachitika pang'onopang'ono nthawi zambiri, koma mawonekedwe ake ndi akulu kwambiri kuposa omwe adachita kale, monga kuyabwa kofulumira, kupuma movutikira, kuthamanga kwa magazi, kuseka kwambiri komanso kuthamanga kwa mtima. Mu zochitika zapadera, ziwengo zimatha kusokoneza moyo wa munthu, vutolo limakonzedwa ndi chithandizo chadzidzidzi, kugwiritsidwa ntchito mwaumoyo ndi kulandira mankhwala.

Mankhwalawa amalembera anthu omwe akufuna insulin.

• Humulin regula - kuchita mwachidule

Humulin P ndi mtundu wopangidwira wa DNA wokhala ndi nthawi yayifupi. Cholinga chachikulu ndikukhazikitsa kagayidwe ka glucose. Ntchito zonse zomwe zimaperekedwa kwa mankhwalawa ndizofanana ndi mfundo yodziwitsidwa ndi ma humulin ena. Njira yothetsera vutoli ikuwonetsedwa kuti igwiritsidwe ntchito ndi anthu omwe ali ndi matenda osokoneza bongo a mtundu woyamba ndi wachiwiri, ndikulimbana ndi thupi pakumwa mankhwala a hypoglycemic ndi mankhwala ophatikiza.
Humulin regula wasankhidwa:

1. Ndi matenda ashuga ketoacidosis.
2. Ketoacidotic ndi hyperosmolar chikomokere.
3. Ngati matenda ashuga adawoneka panthawi yobala mwana (kutengera kulephera kwa zakudya).
4. Ndi njira yaposachedwa yochizira matenda a shuga.
5. Mukasinthira ku insulin yowonjezera.
6. Pamaso pa opareshoni, ndi zovuta za metabolic.

Humulin P imaphatikizidwa chifukwa cha hypersensitivity pamagulu a mankhwala ndipo amadziwika kuti ali ndi hypoglycemia. Dokotala aliyense payekha amalembera wodwalayo mlingo ndi jekeseni wothandizirana ndi kuchuluka kwa shuga m'magazi asanadye komanso pambuyo pa maola 1-2 atatha. Kuphatikiza apo, pakadutsa mlingo, kuchuluka kwa shuga mkodzo ndi mawonekedwe a nthawi ya matendawa amakhudzidwa.

Mankhwala omwe amawaganizira, mosiyana ndi omwe adapita nawo, amatha kuperekedwa kudzera mwa intramuscularly, subcutanely and intrarally. Njira yodziwika kwambiri yoyendetsera ndi yodutsa. Pazovuta zovuta za shuga ndi chikomokere, odwala jekeseni a IV ndi IM amakonda. Ndi monotherapy, mankhwalawa amatumizidwa katatu pa tsiku.Pofuna kupatula kupezeka kwa lipodystrophy, malo a jakisoni amasinthidwa nthawi iliyonse.

Humulin P, ngati pakufunika, imaphatikizidwa ndi mankhwala a mahomoni amtundu wa nthawi yayitali. Zofananira za mankhwala:

1. Actrapid NM.
2. Biosulin R.
3. Insuman Rapid GT.
4. Rosinsulin R.

Mankhwalawa adapangidwa pakusintha kwa insulin

Mtengo wa izi m'malo umayamba kuchokera ku ma ruble 185, Rosinsulin amadziwika kuti ndiwodula kwambiri, mtengo wake lero ndi oposa ruble 900. M'malo insulin ndi analogue ziyenera kuchitika ndi nawo madokotala. Analogue yotsika mtengo ya Humulin R ndi Actrapid, wotchuka kwambiri ndi NovoRapid Flekspen.

• Humulinultralente wotalikira

Insulin Humulin ultralente ndi mankhwala ena omwe amawonetsedwa kuti agwiritsidwe ntchito kwa odwala omwe ali ndi matenda a shuga. Chogulitsidwachi chimakhudzidwa ndi DNA yomwe imapangidwanso ndipo ndi chinthu chomwe chimagwiritsidwa ntchito kwa nthawi yayitali. Kuyimitsidwa kumayambitsidwa patatha maola atatu jakisoni itatha, mphamvu yotsika imatheka mkati mwa maola 18. Malangizo ogwiritsira ntchito akuwonetsa kuti nthawi yayitali ya Humulinultralente ndi maola 24-28.

Dokotala amakhazikitsa mlingo wa mankhwala kwa wodwala aliyense payekhapayekha, poganizira momwe wodwalayo alili. Mankhwalawa amaperekedwa popanda kuwonjezeredwa, jakisoni amapangidwa pansi pa khungu kawiri pa tsiku. Humulin Ultralente akaphatikizidwa ndi mahomoni ena opanga, jakisoni amaperekedwa nthawi yomweyo. Kufunika kwa insulini kumawonjezeka ngati munthu akudwala, akukumana ndi zovuta, amatenga pakati pakamwa, glucocorticoids kapena mahomoni a chithokomiro. Ndipo, mmalo mwake, amachepetsa ndimatenda a chiwindi ndi impso, pomwe mukutenga ma MA inhibitors ndi beta-blockers.
Mndandanda wa mankhwalawa: Humodar K25, Gensulin M30, Insuman Comb ndi Farmasulin.

Ganizirani zotsutsana ndi zoyipa.

Monga ma humulin onse, insulin ultralente imayesedwa chifukwa cha hypoglycemia yomwe ikupitilira komanso chiwopsezo champhamvu cha zigawo zina za chinthu. Malinga ndi akatswiri, zotsatira zoyipa sizimadziwonetsera zokha kuti siziyenda bwino. Zotheka pambuyo pobayikiridwa ndi jakisoni wa lipodystrophy, momwe kuchuluka kwa minofu ya adipose mu minofu ya subcutaneous kumachepa, komanso kukana insulin.

Nthawi zina, mankhwalawa amayambitsa sayanjana.

• Analogue yotchuka ya humulin - Protaphane

Insulin Protafan NM imawonetsedwa kwa matenda osokoneza bongo a mtundu woyamba ndi wachiwiri, pakulimbana kwa sulfonylurea, zotumphukira zamagulu a matenda ashuga, mu nthawi ya opaleshoni ndi yotsatila, kwa amayi apakati.

Protafan imaperekedwa kwa wodwala aliyense payekhapayekha, poganizira zosowa za thupi lake. Malinga ndi malangizo, kufunika kwa mlingo wochita mahomoni ndi 0.3 - 1 IU / kg / tsiku.

Kufunika kumawonjezereka kwa odwala omwe ali ndi insulin kukokana (kuwonongeka kwa kagayidwe kazakudya ka maselo kupita ku insulin), nthawi zambiri izi zimachitika ndi odwala nthawi yakutha komanso kwa anthu omwe ali ndi kunenepa kwambiri. Kuwongolera mlingo wa mankhwalawa kutha kuchitika ndi adokotala ngati wodwala atayamba kudwala, makamaka ngati matenda akupatsirana. Mlingo umasinthidwa matenda a chiwindi, impso ndi matenda a chithokomiro. Protafan NM imagwiritsidwa ntchito ngati jekeseni wofikira mu monotherapy komanso kuphatikiza ndi ma insulin afupiafupi kapena achangu.

Mankhwala

• Achire zotsatira akuyamba ola limodzi jekeseni.
• Kutsitsa kwa shuga kumatenga pafupifupi maola 18.
• Zotsatira zazikulu zimakhala pambuyo pa maola awiri mpaka maola 8 kuchokera pakukonzekera.

Kusintha kotereku kwakanthawi kwamankhwala kumadalira malo omwe amayimitsidwa ndi kuyendetsa galimoto kwa wodwalayo. Izi zimayenera kuganiziridwanso popereka dongosolo komanso kuchuluka kwa makonzedwe.Popeza nthawi yayitali zotsatira zake, Humulin NPH imayikidwa pamodzi ndi insulin yochepa komanso ya ultrashort.

Kugawa ndi kutulutsa thupi:

• Insulin Humulin NPH simalowa mu chotchinga cha hematoplacental ndipo samatuluka m'matumbo a mayi ndi mkaka.
• Inactivine mu chiwindi ndi impso kudzera enzyme insulinase.
• Kuthetsa mankhwalawa makamaka kudzera impso.

Zosafunikira zoyipa zimaphatikizapo:

• hypoglycemia ndimavuto owopsa komanso osakwanira kupanga. Kuwonetsedwa ndi kusazindikira, komwe kumatha kusokonezedwa ndi chikomokere cha hyperglycemic,
• mawonetseredwe amatsitsi omwe amapezeka pamalo a jakisoni (redness, kuyabwa, kutupa),
• kutsutsika
• kupuma movutikira
• hypotension
• urticaria
• tachycardia
• lipodystrophy - mankhwala a kwawo a subcutaneous mafuta.

Kutulutsa Fomu

Kukonzekera kwa insulin Humulin M3 insulini imapezeka mu mawonekedwe a kuyimitsidwa kwa ma subcutaneous makonzedwe mu 10 ml mabotolo, komanso 1.5 ndi 3 ml makatoni, oikidwa m'mabokosi a 5 zidutswa. Cartridges adapangidwa kuti azigwiritsa ntchito syringes ya Humapen ndi BD-pen.

Mankhwala ali ndi hypoglycemic.

Humulin M3 amatanthauza mankhwala obwerezabwereza a DNA, insulin ndi kuyimitsidwa kwa jekeseni kawiri ndi nthawi yayitali.

Pambuyo mankhwala, mankhwala kukonzekera kumachitika pambuyo 30-60 Mphindi. Kuchuluka kwake kumatenga maola awiri mpaka 12, kutalika kwa zotsatirazi ndi maola 18-24.

Ntchito za humulin insulin zimatha kusiyanasiyana malinga ndi malo omwe mankhwalawo amaperekera, kulondola kwa mlingo wosankhidwa, zochita za thupi, wodwala, zina ndi zina.

Zotsatira zazikulu za Humulin M3 zimagwirizana ndi kayendedwe ka kusintha kwa shuga. Insulin ilinso ndi anabolic. Pafupifupi minofu yonse (kupatula ubongo) ndi minofu, insulin imayendetsa kayendedwe ka glucose ndi amino acid, komanso imayambitsa kuthamanga kwa protein anabolism.

Insulin imathandizira kusintha glucose kukhala glycogen, komanso imathandizira kusintha shuga yambiri kukhala mafuta ndikuletsa gluconeogeneis.

Zizindikiro zamagwiritsidwe ntchito ndi zoyipa

1. Shuga mellitus, momwe insulin tikulimbikitsidwa.
2. (matenda ashuga).

1. Kukhazikika hypoglycemia.
2. Hypersensitivity.

Nthawi zambiri pa mankhwala akukonzekera insulin, kuphatikiza Humulin M3, kukula kwa hypoglycemia kumawonedwa. Ngati ili ndi mawonekedwe owopsa, imatha kudzutsa chikumbumtima cha hypoglycemic (kuponderezana ndi kutayika kwa chikumbumtima) ngakhale kupangitsa kuti wodwalayo afe.

Mwa odwala ena, thupi lawo siligwirizana, kuwoneka pakuluma pakhungu, kutupa ndi kufupika kwa malo a jakisoni. Nthawi zambiri, matendawa amadzidzidzikira okha patatha masiku kapena milungu yochepa atayamba chithandizo.

Nthawi zina izi sizimalumikizana ndi kugwiritsa ntchito mankhwalawo pawokha, koma ndi chifukwa cha mphamvu ya zinthu zakunja kapena jakisoni wolakwika.

Pali ziwonetsero zomwe sizigwirizana ndi zachilengedwe. Amachitika kawirikawiri, koma zowopsa. Ndi malingaliro otere, zotsatirazi zimachitika:

• kuvutika kupuma
• kuyamwa kofananira
• kugunda kwa mtima
• dontho mu kuthamanga kwa magazi
• kupuma movutikira
• thukuta kwambiri.

M'mavuto ovuta kwambiri, ziwengo zimatha kusokoneza moyo wa wodwalayo ndipo zimafunikira chithandizo chamankhwala chodzidzimutsa. Nthawi zina insulin m'malo kapena desensitization chofunika.

Mukamagwiritsa ntchito insulin ya nyama, kukana, hypersensitivity kwa mankhwala, kapena lipodystrophy imayamba. Mukamapereka insulin Humulin M3, kuthekera kwa zotulukazi ndi pafupifupi zero.

Malangizo ogwiritsira ntchito

Insulin ya Humulin M3 saloledwa kuperekedwa kudzera m'mitsempha.

Popereka mankhwala a insulin, muyezo ndi mtundu wa makonzedwe ungasankhidwa ndi dokotala. Izi zimachitika payekhapayekha kwa wodwala aliyense payekhapayekha, kutengera mtundu wa glycemia m'thupi lake.Humulin M3 idapangidwa kuti ikwaniritse maulamuliro a subcutaneous, koma amathanso kutumikiridwa intramuscularly, insulin ilola izi. Mulimonsemo, odwala matenda ashuga ayenera kudziwa.

Pang'onopang'ono, mankhwalawa amalowetsedwa pamimba, ntchafu, phewa kapena matako. Mu malo omwewo jakisoni sangaperekedwe mopitilira kamodzi pamwezi. Panthawi ya ndondomekoyi, ndikofunikira kugwiritsa ntchito zida za jakisoni moyenera, kuti singano isalowe m'mitsempha yamagazi, kuti musamayesere malo a jekeseni pambuyo pobayira.

Humulin M3 ndi osakaniza wopangidwa ndi Humulin NPH ndi Humulin Regular. Izi zimapangitsa kuti asakonzekere yankho lisanayambike kwa wodwalayo.

Kukonzekera insulin ya jakisoni, vial kapena cartridge ya Humulin M3 NPH iyenera kukukhidwira maulendo 10 mmanja mwanu, ndikutembenuka, madigiri a 180, gwedezani pang'ono ndi pang'ono. Izi zikuyenera kuchitika mpaka kuyimitsidwa kumakhala ngati mkaka kapena kukhala kwamtambo, ndimadzi amodzimodzi.

Makulidwe a insulin

Kuti mupeze jakisoni moyenera mankhwalawo, muyenera kuchita njira zina zoyambirira. Choyamba muyenera kudziwa malo omwe jakisoniyo, sambitsani manja anu bwino ndikupukuta malowa ndi nsalu yothinidwa ndimowa.

Kenako muyenera kuchotsa kapu yoteteza ku singano ya syringe, kukonza khungu (kutambasula kapena kutsina), ikani singano ndikupanga jakisoni. Kenako singano iyenera kuchotsedwa ndipo masekondi angapo, osafunikira, kanikizani tsamba la jekeseni ndi chopukutira. Pambuyo pake, mothandizidwa ndi kapu yakunja yoteteza, muyenera kumasula singano, kuichotsa ndikubwezeranso chipewacho.

Simungagwiritse ntchito singano yemweyo ya syringe kawiri. Vial kapena cartridge imagwiritsidwa ntchito mpaka itapanda kanthu, ndiye kuti imatayidwa. Ma cholembera a syringe amapangidwira kuti azigwiritsa ntchito payekha.

Zochita Zamankhwala NPH

Kugwiritsa ntchito kwa Humulin M3 kumathandizidwa ndi kayendetsedwe ka mankhwala a pakamwa a hypoglycemic, ethanol, zotuluka za salicylic acid, monoamine oxidase inhibitors, sulfonamides, ACE inhibitors, angiotensin II receptor blockers, osasankha beta-blockers.

Mankhwala a Glucocorticoid, mahomoni akukula, njira zakulera zam'mlomo, danazole, mahomoni a chithokomiro, thiazide diuretics, beta2-sympathomimetics amatsogolera kuchepa kwa mphamvu ya hypoglycemic ya insulin.

Limbitsani kapena, mutafooketsa kudalira insulin yomwe imatha lancreotide ndi ma analogu ena a somatostatin.

Zizindikiro za hypoglycemia zimatsitsidwa ndikutenga clonidine, reserpine ndi beta-blockers.

Migwirizano yogulitsa, yosungirako

Humulin M3 NPH imapezeka pa pharmacy pokhapokha ngati mwalandira mankhwala.

Mankhwalawa amayenera kusungidwa pamtunda wa madigiri 2 mpaka 8, sangathe kuwundana ndikuwonetsa kuwala kwa dzuwa ndi kutentha.

Vial yotseguka ya NPH imatha kusungidwa pamawonekedwe a 15 mpaka 25 kwa masiku 28.

Kutengera ndi kutentha kofunikira, kukonzekera kwa NPH kumasungidwa zaka 3.

Mimba komanso kuyamwa

Ngati mayi woyembekezera ali ndi matenda ashuga, ndiye kuti ndikofunikira kwambiri kuti azilamulira glycemia. Pakadali pano, zofuna za insulin nthawi zambiri zimasintha nthawi zosiyanasiyana. Mu trimester yoyamba, imagwera, ndipo chachiwiri ndi chachitatu chikuwonjezeka, kotero kusintha kwa mankhwalawa kungakhale kofunikira.

Ku Russia, anthu pafupifupi 3 miliyoni ochokera ku dziko lonselo akudwala matenda opatsirana padziko lonse lapansi - matenda ashuga. Nthawi zambiri, anthu odwala matenda ashuga nthawi zambiri amapita ku endocrinologists ndikudziyimira pawokha magazi. Chiwerengero chikuwonjezereka tsiku ndi tsiku, ndipo tsiku lililonse matendawa amalembedwa mwa anthu 200, ndipo 90% yamatenda a shuga.

Mu magawo oyamba, mankhwala amkamwa amagwiritsidwa ntchito kuti achepetse shuga, ndipo chithandizo cha insulin chimatha. Mwa njira, nthawi zambiri chithandizo cha insulin chimayamba mochedwa kwambiri, ngakhale pali mankhwala ambiri okhala ndi mankhwalawa.Mwambiri, mu mawonekedwe a jakisoni, amatha kugawidwa m'magulu atatu.

1. Ma insulini amunthu:

• kopitilira muyeso kochepa
• zochita zazifupi
• nthawi yayitali yochita.

1. Mafuta a insulin yaumunthu:

• kuchitapo kanthu kwa nthawi yayitali.

1. Zosakaniza:

• zochita zosakanikirana (analogue + human),
• zosakanikirana za sing'anga ndi zazifupi akuchita insulin.

Kukonzekera kumapangidwa ndi makampani osiyanasiyana, ndipo ndi dokotala yekha yemwe ayenera kusankha yoyenera. Palibe chifukwa chake musalowe m'malo mankhwalawo, chifukwa izi zitha kupangitsa kuti thupi liziganiza mosasamala, chifukwa cha kuchuluka kwa mankhwala omwe sanasinthe. Ngakhale gawo laling'ono lothandizanso lingathe kuyambitsa mavuto ambiri. Othandizira angapo a protamine Hagedorn omwe satchulidwa pagome amayimira mankhwala omwe amagwiritsidwa ntchito kwambiri ku Russia.

Kodi pali kusiyana kotani pakati pa NPH insulin ndi insulin ina?

Mankhwala a insulin ndi protamine ndi mankhwala osokoneza bongo apakatikati. Chidule chachilendo chimachokera ku dzina lachi Latin loti Neutral Protamine Hagedorn. Ku Russia, mutha kupeza mayina ena osagulitsa a mankhwalawa (PTsI kapena isofan).

Mankhwalawa amapezeka ngati kuyimitsidwa kwa ma sc makonzedwe olimba a insulin. Chifukwa chake, kukonzekera kotsalira kumakhala pansi pa khungu kwa nthawi yayitali, kulowa m'magazi pang'onopang'ono. Pankhani imeneyi, insulin, yomwe imatchedwa npx, imagwira ntchito kwa maola 12-16, yomwe imakhala yotalikirapo 2-3 kuposa ma insulini ena a anthu.

Kuti mukwaniritse zopindulitsa kwambiri za NPH insulin, ndikofunikira kutsatira njira yochitira jakisoni wa sc. Kafukufuku wasonyeza kuti ndi 9% yokha ya odwala onse omwe amagwiritsa ntchito isofan molondola omwe amalowetsa muyezo wofunikira, pomwe ena onse samanyalanyaza njira yoyenera.

Ma NPH ambiri amapangidwa ndi makampani osiyanasiyana opanga mankhwala ku cartridgeges pazotsatira, komabe, si makampani onse omwe amawona kulondola kwa mankhwalawa popereka mankhwala.

Kukonzekera kwa NPH kumasiyanitsidwa pakati pawo, kumagawana mu insulin ya nkhumba ndi anthu. Mukasinthana ndi mankhwala amtundu wina, kapangidwe kamankhwala kamene kamalowa m'magazi amasintha, chifukwa ma amino acid omwe amapezeka mwa anthu ndi porcine insulin ndi osiyana.

Zisonyezero zakugwiritsa ntchito Humulin

Humulin ndi yoyenera kugwiritsidwa ntchito ndi amayi oyembekezera omwe amadalira insulin omwe ali ndi mbiri ya matenda a shuga a 2. A endocrinologist atha kukuwuzani jakisoni wa humulin kwa nthawi yoyamba matenda a shuga amapezeka mwa wodwala, kapena mankhwala ena atasinthidwa (ngati akuwonetsedwa), kuti apitirize insulin.

Njira Yoyambira Molondola

1. Kukhazikitsidwa kwa mtundu uliwonse wa insulin kuyenera kukhala kwakanthawi, kapena kutengera deta ya glucometer.
2. Tsamba la jakisoni liyenera kusinthidwa nthawi iliyonse.
3. Mbale yokhala ndi mankhwala a NPH kapena cholembera chokhala ndi katemera wa humulin iyenera kutembenuka kwathunthu maulendo 20 musanagwiritse ntchito, koma osagwedezeka.
4. Ngati mugwiritsa ntchito humulin mu vial, ndiye kuti simungagwiritse ntchito singano imodzi (singano) pobwereza kayendetsedwe kake, lamuloli limagwiranso ntchito pa zolembera za syringe.
5. Musagwiritse ntchito zolembera za odwala ena.
6. Singano yochokera ku cholembera imayenera kuchotsedwa nthawi yomweyo.
7. Ngati gawo la insulin likuyenda kuchokera pakhungu musadzabayira jakisoni wa humulin kachiwiri.
8. Ngati mumakonda kumwa mowa, kapena mowa umapukuta jakisoni, ndiye dikirani mpaka mowawo utatha khungu.
9. Ngati makhiristu oyera ofanana ndi mawonekedwe achisanu aonekera m'makoma a botolo, simungathe kuwagwiritsa ntchito.
10. Humulin Regular ndi NPH imatha kusakanikirana mu syringe imodzi, pomwe Humulin yokhazikika imayenera kulembedwa koyamba. Lamuloli limalembedwa pokhapokha ndi humulin, ndizosatheka kusakaniza mankhwala a magulu ena mu syringe imodzi ya insulin.

Monga isofan ina iliyonse, Humulin imatha kuyambitsa kuwonetsa kwa hypoglycemic.Pankhani yogwiritsa ntchito mankhwala a NPH, ndi humulin makamaka, hypoglycemia mwa odwala imayamba nthawi zambiri kugona, komanso m'mawa kwambiri. Nthawi zina zovuta kwambiri, hypoglycemia mukamamwa mankhwalawa zimatha kuyambitsa khungu kapena kufa. Ngati pazifukwa zilizonse mukulephera kuwongolera kuchuluka kwa shuga kwakanthawi mankhwala ataperekedwa, onetsetsani kuti wina amene angapereke chithandizo choyamba kapena kuyimbira ambulansi akudziwa za izi.

Zotsatira zoyipa zomwe zimagwiritsidwa ntchito pakugwiritsa ntchito humulin ndizosowa NPH, koma zitha kukhala zowopsa pamoyo, mwachitsanzo: kupuma movutikira komanso ngati kuchepa kwa kuthamanga kwa magazi.

Zotsatira zoyipa ndizotsatira kwa onse a NPH, chifukwa aliyense angayambitse sayanjana malo opangira jakisoni.

Kuchepetsa ndi pakati

Amayi ena omwe ali ndi matenda ashuga posachedwa amaganiza za ana. Molondola, momwe mungathere, ngati insulin imagwiritsidwa ntchito kukonza milingo ya shuga, makamaka, humulin yolembedwa ndi NPH.

Amayi ambiri amanyalanyaza thanzi lawo, kusamalira kuti kuwopsa kwa mankhwalawa sikuyambitsa masinthidwe mwa mwana. Komabe, ndizosatheka kunyalanyaza kumwa mankhwala kuti adzivulaze, chifukwa izi zingasokoneze kukula kwa mwana.

Ndikofunika kukonzekereratu za mimba isanakwane, ndi kudziwitsa adotolo osati zitangochitika, komanso munakonzekera. Munthawi iliyonse, kuyendera kwa endocrinologist ndikofunikira, chifukwa ndiamene amayenera kuthana ndi kusintha kwa mankhwalawa. Mzimayi akuyenera kukhala okonzekera kuti nthawi yoyamba mlingo wa insulin uzikhala wotsika kuposa masiku onse, ndipo chachiwiri ndi chachitatu chiziwonjezeka.

Pambuyo pobadwa, mayi woyamwitsa amafunikanso kuyang'aniridwa kwa endocrinologist ndikusintha kwa mankhwala, kapena zakudya.

Pomaliza

Mankhwala a nthawi yayitali achitapo kanthu kena ndipo tsopano ndi 1946. Kwa zaka 70, odwala ambiri adakumana ndi insulin yotere, ndikupitilizabe kugwiritsa ntchito humulin ndi protofan, chifukwa NPH imalembedwa ndi dokotala, ndipo ngati zikuwonetsa zofunika, isofan ndikofunikira.

Zachidziwikire, palibe amene angokhala chete kuti, monga mankhwala onse, gulu ili la mankhwala lilinso ndi zolakwika zake. Kwa achinyamata, mwachitsanzo, mankhwalawa samakhala oyenera, chifukwa muyenera kuyiwala za zokhwasula-khwasula ndikutsatira mosamalitsa chakudya, osati chokhacho. Chiwopsezo cha hypoglycemia ndikuphwanya njira zamakonzedwe, ndikuwunika kwambiri shuga.

Odwala omwe ali ndi matenda ashuga amayesa kupewetsa insulin chithandizo, chomwe sicholondola konse, chifukwa izi sizingalephereke, ndipo kupatsidwa chithandizo chamankhwala chamtunduwu ndi nkhani yanthawi yochepa chabe. Kuopa kuti jakisoni ndi insulin kudzakuthandizani kuti musakhale ndi moyo womwe mumazolowera kupita mwachangu.

Fomu ya Mlingo: & nbsp kuyimitsidwa kwa makulidwe osakanikira:

1 ml muli:

ntchito: insulin yamunthu 100 ME,

zokopa: metacresol 1.6 mg, phenol 0,65 mg, glycerol (glycerin) 16 mg, protamine sulfate 0,348 mg, sodium hydrogen phosphate heptahydrate 3,78 mg, zinc oxide - qs kuti apange zinc ions zosaposa 40 μg, 10% hydrochloric acid solution - Qs to pH 6.9-7.8, 10% sodium hydroxide solution - qs to pH 6.9-7.8, madzi a jakisoni - mpaka 1 ml.

Kuyimitsidwa ndi koyera, komwe kumachoka, ndikupanga koyera komanso kowoneka bwino - kopanda mawonekedwe kapena kopanda mtundu. Mtengo umasinthidwa mosavuta ndikugwedezeka modekha.

Gulu la Pharmacotherapeutic: wothandizira wa hypoglycemic - nthawi yayitali insulin ATX: & nbsp

A.10.A.C Kutalika kwapakatikati kosungira ndi mawonekedwe awo

Humulin® NPH ndi insulin yowerengeka ya anthu.

Chochita chachikulu cha insulin ndi kuphatikiza shuga kagayidwe.Kuphatikiza apo, imakhala ndi anabolic komanso anti-catabolic zotsatira zosiyanasiyana zamthupi. Mu minofu ya minofu, pali kuchuluka kwa glycogen, mafuta acid, glycerol, kuchuluka kwa mapuloteni komanso kuwonjezereka kwa kumwa ma amino acid, koma nthawi yomweyo kumachepa mu glycogenolysis, gluconeogeneis, ketogeneis, lipolysis, proteinabolism ndi kutulutsidwa kwa ma amino acid.

Humulin® NPH ndiakonzekereratu. Kukhazikika kwa mankhwala ndi ola limodzi pambuyo pa kukonzekera, mphamvu yayikulu imakhala pakati pa maola awiri ndi asanu ndi atatu, kutalika kwa nthawi ndi maola 18-20.

Kusiyana kwamwini pantchito ya insulin kumadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi, ndi zina zambiri.

Pharmacokinetics: kukwana kwathunthu kwa mayamwidwe ndi kuyambika kwa mphamvu ya insulin kumadalira malo a jakisoni (m'mimba, ntchafu, matako), mlingo (kuchuluka kwa insulin), kuchuluka kwa insulini mu mankhwala, etc. umagawidwa mosiyanasiyana kudutsa minyewa ndipo osadutsa chotchinga chachikulu komanso kulowa mkaka wa m'mawere. Amawonongedwa ndi insulinase makamaka m'chiwindi ndi impso. Amachotsa impso (30-80%). Zowonetsa:

- Matenda a shuga odwala matenda a insulin,

- matenda ashuga panthawi yoyembekezera.

Hypersensitivity kupita ku insulin kapena chimodzi mwazinthu za mankhwala,

Mimba ndi kuyamwa:

Pakati pa nthawi yayitali, ndikofunikira kuti pakhale chitetezo chabwino cha glycemic mwa odwala omwe amalandira insulin. Kufunika kwa insulin nthawi zambiri kumachepetsa panthawi yoyambirira ndikuwonjezeka panthawi yachiwiri komanso yachitatu. Nthawi yobadwa pambuyo pokhapokha ndipo mwayamba kubadwa, zofunika za insulin zimatha kugwa kwambiri. Odwala omwe ali ndi matenda ashuga amalangizidwa kuti azidziwitse dokotala wawo za kubereka kapena kukonzekera pakati.

Odwala omwe ali ndi matenda a shuga mellitus nthawi yoyamwitsa angafunikire kusintha kwa insulin, zakudya, kapena zonse ziwiri.

Mlingo ndi makonzedwe:

Mlingo wa Humulin® NPH umatsimikiziridwa ndi dokotala aliyense payekha malinga ndi kuchuluka kwa shuga m'magazi. Mankhwalawa amayenera kuperekedwa mwachangu.

Kutentha kwa mankhwala omwe amaperekedwa kuyenera kukhala kutentha kwambiri.

Jakisoni wotsekemera uyenera kuchitidwa paphewa, ntchafu, matako kapena m'mimba. Masamba a jakisoni ayenera kusinthidwa kuti malo omwewo sawagwiritsanso ntchito mwina kamodzi pamwezi. Ndi subulinaneous ya insulin, chisamaliro chimayenera kumwedwa kuti musalowe m'mitsempha yamagazi pakubaya. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa. Odwala ayenera kuphunzitsidwa bwino kugwiritsa ntchito insulin yobereka.

Ndondomeko ya insulin makonzedwe ali payekha.

Kukonzekera kwa Humulin® NPH mu mbale

Zisanayambe kugwiritsidwa ntchito, Mbale za Humulin® NPH ziyenera kukulitsidwa kangapo pakati pamafinya mpaka insuliniyo itayambanso kukonzedwa mpaka itakhala yunifolomu yamadzi kapena mkaka. Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera.

Musagwiritse ntchito insulini ngati ili ndi mapokoso mukasakaniza. Osagwiritsa ntchito insulin ngati tinthu tating'ono tomwe timamatira pansi kapena makoma a vial, ndikupanga mawonekedwe a frosty.

Gwiritsani ntchito syringe ya insulin yomwe ikufanana ndi kuchuluka kwa insulin.

Ya Humulin® NPH m'makalata

Musanagwiritse ntchito, makatiriji a Humulin® NPH ayenera kugulitsidwa pakati pa manja khumi ndikugwedezeka, kutembenuka kwa 180 ° komanso khumi mpaka insulini itatsitsimuka kwathunthu mpaka itasandulika madzi osungunuka kapena mkaka. Osagwedezeka mwamphamvu, chifukwa izi zingapangitse mawonekedwe a chithovu, omwe amatha kusokoneza mlingo woyenera.Mkati mwako katoni kalikonse ndi kakang'ono. mpira wamagalasi omwe amathandizira kusakanikirana kwa insulin. Musagwiritse ntchito insulini ngati ili ndi mapokoso mukasakaniza.

Chida cha cartridge sichimalola kuphatikiza zomwe zili ndi insulin zina mwachindunji mu katiriji palokha: makatiriji sanapangidwire kuti mudzazidwe.

Pamaso pa jekeseni, ndikofunikira kudziwa bwino zomwe wopanga amagwiritsa ntchito cholembera kuti apereke insulin.

Mankhwala Humulin ®NPH mu syringe yachangu

Pamaso jakisoni, muyenera kuwerenga Malangizo a QuickPen ™ Syringe pen Instruction.

Hypoglycemia ndizotsatira zoyipa zomwe zimachitika pokhazikitsa kukonzekera kwa insulin, kuphatikiza Humulin ® NPH. Hypoglycemia yamphamvu imatha kutha kwa chikumbumtima ndipo, mwapadera, amafa.

Thupi lawo siligwirizana : Odwala amatha kukumana ndi vuto lodana ndi mtundu wa hyperemia, edema, kapena kuyabwa pamalowo. Izi zimachitika pakatha masiku angapo mpaka milungu ingapo. Nthawi zina, izi zimachitika chifukwa cha zifukwa zosakhudzana ndi insulin, mwachitsanzo, mkwiyo pakhungu ndi wothandizira kuyeretsa kapena jakisoni wosayenera.

Zosagwirizana zimachitika oyambitsa insulin, samachitika kangapo, koma amakhala akulu kwambiri. Amatha kuwonetsedwa ndi kuyabwa kwakukulu, kupuma movutikira, kufupika, kuchepa kwa magazi, kuchuluka kwa mtima, komanso thukuta kwambiri. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pangozi yoopsa. Nthawi zina mankhwalawa amakumana ndi Humulin® NPH, chithandizo chofunikira chimafunikira. Mungafunike kusintha kwa insulin, kapena kutsimikiza mtima.

Ndi kugwiritsa ntchito nthawi yayitali - chitukuko ndichotheka lipodystrophy pamalo opangira jekeseni.

Milandu ya chitukuko cha edema yadziwika, makamaka ndi kusintha kwachulukidwe ka shuga m'magazi motsutsana ndi maziko a insulin Therapy poyambira osakhutiritsa glycemic control (onani gawo "Maupangiri Apadera").

Mankhwala osokoneza bongo a insulin amachititsa hypoglycemia, limodzi ndi zotsatirazi Zizindikiro : uchidakwa, thukuta kwambiri, tachycardia, kufooka kwa khungu, mutu, kunjenjemera, kusanza, chisokonezo. Nthawi zina, mwachitsanzo, pakhale nthawi yayitali kapena kuwunika kwambiri matenda a shuga, Zizindikiro, zomwe zimayambitsa hypoglycemia zimatha kusintha.

Wofatsa hypoglycemia mutha kuyimitsa pakumeza shuga kapena shuga. Kusintha kwa mlingo wa insulin, zakudya, kapena zolimbitsa thupi kungafunike.

Kuwongolera Hypoglycemia wabwino angathe kuchitidwa ntchito mu mnofu kapena subcutaneous makonzedwe a glucagon, kenako ingestion wa chakudya.

Zambiri hypoglycemia motsatana ndi chikomokere, kukomoka kapena kupweteka kwamitsempha, kuyimitsidwa ndi kutsekeka / kutsekeka kwa glucagon kapena kulowerera kwamitsempha yokhazikika ya 40% ya dextrose (glucose). Pambuyo pozindikira, wodwalayo ayenera kupatsidwa chakudya chamagulu owonjezera chakudya kuti asayambenso kukonzekera hypoglycemia.

Ngati mukufunika kugwiritsa ntchito mankhwala ena, kuphatikiza insulin, muyenera kufunsa dokotala (onani gawo "Malangizo apadera").

Kuwonjezeka kwa mlingo wa insulini kungafunike poika mankhwala omwe amalimbikitsa kuchuluka kwa shuga m'magazi, monga : kulera kwapakamwa, glucocorticosteroids, mahomoni okhala ndi chithokomiro, beta 2 --adrenomimetics (mwachitsanzo ritodrin, terbutaline), thiazide diuretics, diazoxide, zotumphukira za phenothiazine.

Kuchepetsa kuchuluka kwa insulini kungafunike popereka mankhwala omwe amachepetsa kuchuluka kwa shuga m'magazi, monga : beta-blockers, ndi mankhwala okhala ndi ethanol, mankhwala a anabolic, fenfluramine, guanethidine, tetracyclines, mankhwala a m'kamwa a hypoglycemic, salicylates (mwachitsanzo), mankhwala a sulfanilamide, ma antidepressants (monoamine oxidase inhibitors), angiotensin inhibitors, ndi angiotensin inhibitors Beta-blockers, clonidine, amatha kuphimba mawonetseredwe a zizindikiro za hypoglycemia.

Zotsatira zakusakanikirana kwa insulin yaumunthu ndi insulin yakuchokera kwa nyama kapena insulin ya anthu yopangidwa ndi ena omwe sanaphunzire.

Kusamutsa wodwala kupita ku mtundu wina kapena kukonzekera kwa insulin ndi dzina lina lamalonda kuyenera kuchitika moyang'aniridwa ndi achipatala. Kusintha kwa ntchito, mtundu (wopanga), mtundu (Wokhazikika, NPH, ndi zina) zamtundu (nyama, munthu, insulin analogs) ndi / kapena njira yopanga (DNA recombinant insulin kapena insulini yachikhalidwe) ingafune kusintha kwa mlingo.

Kwa odwala ena, kusintha kwa mlingo kumakhala kofunikira pakusintha kuchokera ku insulin yochokera ku nyama kupita ku insulin ya anthu. Izi zitha kuchitika kale poyambilira kukonzekera kwa insulin ya anthu kapena pang'onopang'ono pakangotha ​​milungu ingapo kapena miyezi ingapo atasamutsidwa. Zizindikiro zakutsogolo kwa hypoglycemia panthawi ya insulin yaumwini mwa odwala ena akhoza kutchulidwa kochepa kapena zosiyana ndi zomwe zimawonedwa panthawi ya insulin ya nyama. Ndi matenda a shuga m'magazi.

mwachitsanzo, chifukwa cha insulin Therapy, zonse kapena zizindikiro zina zakutsogolo kwa hypoglycemia zimatha, zomwe odwala ayenera kudziwitsidwa. Zizindikiro zakutsogolo kwa hypoglycemia zimatha kusintha kapena kusalankhula pang'ono ndi njira yayitali ya matenda a shuga, matenda ashuga a m'mimba, kapena chithandizo chamankhwala monga beta-blockers.

Mlingo wosakwanira kapena kusiya kulandira chithandizo, makamaka kwa odwala omwe ali ndi vuto la matenda ashuga 1, kungayambitse matenda a hyperglycemia ndi matenda ashuga a ketoacidosis (mikhalidwe yomwe ikhoza kukhala yowopsa kwa wodwalayo).

Kufunika kwa insulini kumatha kuchepa ndi kusakwanira kwa adrenal gland, gland planditary kapena chithokomiro, ndi aimpso kapena kwa chiwindi. Ndi matenda ena kapena kupsinjika kwamalingaliro, kufunikira kwa insulin kungakulitse. Kuwongolera mlingo wa insulin kungafunikenso ndi kuwonjezeka kwa zochitika zolimbitsa thupi kapena kusintha kwa zakudya zomwe mumakonda.

Mukamagwiritsa ntchito insulin pokonzekera limodzi ndi mankhwala a gulu la thiazolidinedione, chiopsezo chotenga matenda a edema ndi matenda a mtima omwe amalephera chikuwonjezereka, makamaka kwa odwala omwe ali ndi matenda amtima komanso kupezeka kwa zinthu zomwe zingayambitse matenda osalephera a mtima.

QUICKPEN ™ SYRINGE HANDLES

Humulin® Regular QuickPen ™,Humulin® NPH QuickPen ™,Humulin® M3 QuickPen ™

MALANGIZO OTHANDIZA MALO OTSATIRA

CESANI LERANI ZINSINSI izi ASANAYITSE

Pulogalamu Yopanga Mwachangu Yofulumira ndiyosavuta kugwiritsa ntchito. Ndi chipangizo chothandizira kuperekera insulin (cholembera insulini cholembera) yomwe ili ndi 3 ml (ma 300) pakukonzekera kwa insulin ndi ntchito ya 100 IU / ml. Mutha kubaya kuchokera 1 mpaka 60 magawo a insulin pa jakisoni. Mutha kukhazikitsa mlingo molondola ndi umodzi. Ngati mwayika mayunitsi ambiri. Mutha kukonza mankhwalawa osataya insulin.

Musanagwiritse ntchito syPinge ya QuickPen, werengani bukuli ndikutsatira malangizo ake ndendende. Ngati simutsatira malangizowa, mutha kulandira inshuwaransi yotsika kwambiri kapena kwambiri.

Penti ya QuickPen Syringe ya insulin iyenera kugwiritsidwa ntchito ndi inu nokha.Osadutsa cholembera kapena singano kwa ena, chifukwa zimatha kufalitsa kachilomboka. Gwiritsani ntchito singano yatsopano jekeseni iliyonse.

Musagwiritse ntchito cholembera ngati gawo lake lina lawonongeka kapena lawonongeka. Nthawi zonse tengani cholembera chopanda kanthu ngati mungataye cholembera kapena chikaonongeka.

Kukonzekera Kwachangu kwa Syninge

Werengani ndikutsatira malangizo ogwiritsira ntchito mankhwalawa.

Chongani cholembera pa cholembera chisanafike jakisoni aliyense kuti mutsimikizire kuti tsiku lomwe linatha limatha ndipo mukugwiritsa ntchito mtundu woyenera wa insulini, musachotse cholembera ku cholembera.

Zindikirani : Mtundu wa batani lothamanga la cholembera cha QuickPen umagwirizana ndi mtundu wa Mzere pa cholembera cholembera ndipo zimatengera mtundu wa insulin. Mu buku ili, batani la mlingo limayimitsidwa. Mtundu wa beige wa cholembera cha syringe wa QuickPen umawonetsera kuti umapangidwa kuti ugwiritse ntchito ndi zinthu za Humulin.

Dokotala wanu wakupangira mtundu wa insulin wabwino kwambiri. Kusintha kulikonse kwa mankhwala a insulin kuyenera kuchitidwa kokha moyang'aniridwa ndi dokotala.

Musanagwiritse ntchito cholembera, onetsetsani kuti singanoyo imalumikizidwa kwathunthu ndi cholembera.

Tsatirani malangizo omwe aperekedwa apa.

Mafunso omwe amafunsidwa pafupipafupi okonzekera kukonzekera PPP Sypinge cholembera

- Kodi kukonzekera kwanga kwa insulin kuyenera kuwoneka bwanji? Kukonzekera kwina kwa insulini ndi kuyimitsidwa kotsekemera, pomwe ena ndi mayankho omveka, onetsetsani kuti mukuwerenga malongosoledwe a insulin m'malamulo omwe aikidwa kuti mugwiritse ntchito.

- Ndichite chiyani ngati mlingo wanga waposa 60? Ngati mlingo womwe wakupatsani uli pamwamba pa mayunitsi 60, mufunika jekeseni wachiwiri, kapena mutha kulankhulana ndi dokotala za nkhaniyi.

- Chifukwa chiyani ndigwiritse ntchito singano yatsopano pa jekeseni iliyonse? Ngati singano agwiritsidwanso ntchito, mutha kulandira mulingo wolakwika wa insulin, singano imatha kutsekeka, kapena cholembera sichingathe, kapena mutha kutenga kachilomboka chifukwa chazovuta.

- Ndichite chiyani ngati sinditsimikiza kuchuluka kwa insulini yanga ? Kwezani chogwirira kuti nsonga ya singano ilowe pansi. Mulingo wapa cartridge wosonyeza bwino kuchuluka kwa insulini yotsalira. Manambalawa ASATHA kugwiritsidwa ntchito kukhazikitsa mlingo.

"Ndichite chiyani ngati sindingathe kuchotsa cholembera ku cholembera?" Kuti muchotse chipewa, kokerani. Ngati mukuvutikira kuchotsa chipewa, sinthani mosamala kachulukidwe kake ndi kuyerekezera kuti mumasule, ndiye kuti mukoka kuti muchotse kapuyo.

Kuyang'ana cholembera cha SyPinge cha QuickPen cha Insulin

Onani kuchuluka kwanu kwa insulin nthawi zonse. Chitsimikizo cha kutulutsidwa kwa insulini kuchokera ku cholembera kuti chichitike jekeseni iliyonse isanafike pang'onopang'ono mpaka inshuwaransi ikawonekere kuonetsetsa kuti cholembera chakonzeka.

Ngati simukuyang'ana insulin yanu musanayambe kudwala, mutha kulandira insulin yochepa kwambiri kapena yambiri.

Mafunso Omwe Amakonda Kufunsa za Kuchita Macheke a Insulin

- Chifukwa chiyani ndiyenera kuwerengera insulin yanga isanadye jakisoni iliyonse?

1. Izi zikuwonetsetsa kuti cholembera chakonzekera kumwa.

2. Izi zikutsimikizira kuti chinyengo cha insulin chimatuluka mu singano mukakanikiza batani la mlingo.

3. Izi zimachotsa mpweya womwe ungatenge mu singano kapena katoni ya insulin panthawi yovomerezeka.

- Ndiyenera kuchita chiyani ngati sindingathe kukanikiza bwino batani la mlingo panthawi yachangu ya insulin?

1. Phatikizani singano yatsopano.

2. Yang'anani insulin kuchokera ku cholembera.

"Ndichitenji ndikawona makamu am'kati mwa katiriji?"

Muyenera kufufuza insulin kuchokera ku cholembera. Kumbukirani kuti simungasunge cholembera ndi singano yolumikizidwa, chifukwa izi zimatha kupangitsa kuti pakhale thovu. Khungu laling'ono la mpweya silikuwakhudza mankhwalawo, ndipo mutha kulowa muyezo wanu mwachizolowezi.

Kukhazikitsidwa kwa mlingo wofunikira

Tsatirani malamulo a asepsis ndi antiseptics omwe adokotala amuuzani.

Onetsetsani kuti mwalowa muyezo wofunikira mwa kukanikiza ndikuyika batani la mlingo ndikuwerengera pang'onopang'ono mpaka 5 musanachotsere singano. Ngati insulin ikudontha kuchokera singano, mwina simunagwire singano pansi pa khungu lanu nthawi yayitali.

Kukhala ndi dontho la insulin pamsana pa singano ndikwabwinobwino. Izi sizingakhudze mlingo wanu.

Cholembera cha syringe sichingakulolezeni kujambula mlingo wopitilira muyeso wamagulu a insulin otsalira mu katoni.

Ngati mukukayika kuti mwapereka mlingo wonse, musamaperekenso mlingo wina. Imbani woimira wanu wa Lilly kapena dokotala wanu kuti akuthandizeni.

Ngati mlingo wanu uposa kuchuluka kwa zigawo zomwe zatsalira mu cartridge, mutha kuyika kuchuluka kwa insulini mu cholembera ichi ndipo mugwiritse ntchito cholembera chatsopano kuti mumalize muyeso wofunikira, Pena lembani mlingo wonse pogwiritsa ntchito cholembera chatsopano.

Osayesa kubaya insulin potembenuza batani la mlingo. Simulandila insulin ngati mutembenuza batani la mlingo. Muyenera kusinthitsa batani la mlingo molunjika kuti mulandire mlingo wa insulin.

Musayese kusintha mlingo wa insulin panthawi ya jakisoni.

Singano yomwe imagwiritsidwa ntchito iyenera kutayidwa malinga ndi zofunikira zotaya zinyalala zakuchipatala.

Chotsani singano pambuyo pa jekeseni iliyonse.

Mafunso Ofunsidwa Kawirikawiri

- Chifukwa chovuta kukanikiza batani la mlingo, ndikuyesera liti kubaya?

1. Singano yanu itha kumangidwa. Yesani kuphatikiza singano yatsopano. Mukachita izi, mutha kuwona momwe insulin imatuluka mu singano. Kenako yang'anani cholembera.

2. Makina osindikiza mwachangu pa batani la mlingo amatha kupangitsa batani kukanikiza. Kutsinikiza pang'onopang'ono batani la mlingo kungapangitse kukanikiza mosavuta.

3. Kugwiritsa ntchito singano yayikulu kukuthandizira kuti musakanize kubatani.

Funsani othandizira anu azaumoyo za kukula kwa singano kopambana.

4. Ngati kukanikiza batani pakati pa dongosolo la kumwa kumakhalirabe zolimba pambuyo poti mfundo zonse pamwambazi zithe, ndiye kuti cholembera sichingasinthidwe.

- Ndiyenera kuchita chiyani ngati syringe yachala ya Peneni ikagwiritsidwa ntchito?

Cholembera chako chidzakhala cholimba ngati nkovuta kuti ugwiritse kapena kubayira. Popewa cholembera kuti chisamatirire:

1. Phatikizani singano yatsopano. Mukachita izi, mutha kuwona momwe insulin imatuluka mu singano.

2. Chongani insulin.

3. Ikani mlingo wofunikira ndi jakisoni.

Osayesa kupaka cholembera chimbudzi, chifukwa izi zitha kuwononga gawo la cholembera.

Kukanikiza batani la mlingo kumatha kulowa ngati zinthu zakunja (dothi, fumbi, chakudya, insulini kapena zakumwa zilizonse) zikalowa mkatikati mwa syringe. Musalole zodetsa kuti zilowe mu cholembera.

- Chifukwa chiyani insulini imatuluka mu singano nditamaliza kupereka mlingo wanga?

Mwina mwachotsa singano mwachangu kwambiri pakhungu.

1. Onetsetsani kuti mukuwona nambala ya "0" pazenera la chisonyezo.

2. Kupereka mlingo wotsatira, kanikizani ndikuyika batani la mlingo ndikuwerengera pang'onopang'ono mpaka 5 musanachotsere singano.

- Ndichitenji ngati mlingo wanga wakhazikika, ndipo batani loyamwa mwangozi limakhala kuti limakumbukiranso mkatikati popanda singano yomata ndi cholembera?

1. Sinthani batani la mlingo kukhala zero.

2. Phatikizani singano yatsopano.

3.Onani kuchuluka kwanu kwa insulin.

4. Ikani mlingo ndi jakisoni.

"Ndingatani ngati nditayamwa mlingo woyenera (wotsika kwambiri kapena wotsika kwambiri)?" Sinthani batani la mlingo kumbuyo kapena kutsogolo kuti mukonze uthengawo.

- Ndiyenera kuchita chiyani ndikawona kuti insulini imatuluka mu cholembera pakasankhidwa kapena kusintha kwa mlingo? Musamapereke mlingo, chifukwa mwina simungalandire mlingo wathunthu. Khazikitsani cholembera ku nambala ya zero ndikuyang'ananso kuchuluka kwa insulini kuchokera ku cholembera (onani gawo "Kuyang'ana Pangongole Yotumizira Ya QuickPen Kuti Ipatsidwe Insulini"). Khazikitsani mlingo woyenera ndi jakisoni.

- Ndichite chiyani ngati kumwa kwathunthu sikukwaniritsidwa? Cholembera sichingakulorengenso kuti muike mankhwalawo mopitilira kuchuluka kwa kuchuluka kwa insulini yotsalira mukatoni. Mwachitsanzo, ngati mukufuna mayunitsi 31, ndipo magawo 25 okha atsala mu katiriji, ndiye kuti simungathe kudutsa nambala 25 mukamayikiratu. Osayesa kukhazikitsa mlingowo podutsa nambala iyi. Ngati gawo loyenera latsala m'khola, mutha:

1. Lowetsani gawo ili, kenaka lembani mlingo wotsalira pogwiritsa ntchito cholembera chatsopano, kapena

2. Lowetsani mlingo wathunthu kuchokera ku cholembera chatsopano.

- Chifukwa chiyani sindingathe kukhazikitsa mlingo kuti mugwiritse ntchito insulin yaying'ono yomwe yasiyidwa mu katiriji yanga? Cholembera chimbalecho chimapangidwa kuti chilolere kuyamwa kwa magawo 300 a insulin. Chida cha cholembera sichitha kuteteza katiriji kuti lisatheretu, chifukwa kuchuluka kwa insulini komwe kumakhalabe ndi kathumba sikungavulazidwe ndikulondola.

Kusunga ndi kutaya

Cholembera sichingagwiritsidwe ntchito ngati chakhala kunja kwa firiji kwa nthawi yopitilira nthawi yomwe idafotokozedwa mu Maupangiri Ogwiritsira Ntchito.

Osasunga cholembera ndi singano yake. Ngati singanoyo yatsala kuti ikanikizidwe, insulansi ingatuluke m'timalo, kapena insulin ikhoza kupukuta mkati mwa singano, potseka singano, kapena thovu la mpweya litha kupanga katiriji.

Zilembera zomwe sizikugwiritsidwa ntchito ziyenera kusungidwa mufiriji kutentha kwa 2 ° C mpaka 8 ° C. Osagwiritsa ntchito cholembera kuti chitauma.

Cholembera cha syringe chomwe mukugwiritsa ntchito pano chiyenera kusungidwa pa kutentha osaposa 30 ° C komanso pamalo otetezedwa kuti asatenthe ndi kutentha.

Fotokozerani Malangizowo kuti mugwiritse ntchito pozindikira bwino malo osungirako cholembera.

Sungani cholembera kuti chisafike kwa ana.

Tayetsani singano pakugwiritsa ntchito polemba, kupangira zotengera (mwachitsanzo, zotengera zama biohazardous zvinhu kapena zinyalala), kapena monga momwe katswiri wanu wazachipatala adakulimbikitsira.

Taya zolembera zomwe mugwiritse ntchito singano popanda singano zophatikizidwa kwa iwo komanso mogwirizana ndi malingaliro a dokotala.

Osabwezanso zotengera zazitali.

Funsani dokotala wanu za momwe mungathere kutaya zotengera zotayikira m'dera lanu.

Humulin® ndi Humulin® mu QuickPen ™ Syringe pen ndizizindikiro za Eli Lilly & Company.

QuickPen ™ Syringe pen imakwaniritsa zofunikira zenizeni za dosing ndi zofunikira za ISO 11608-1: 2000

Onetsetsani kuti muli ndi zinthu zotsatirazi:

□ Kuthamangitsa Pen Syringe

□ Chingwe chatsopano cha cholembera

□ Swab wothira mowa

Zophatikizira ndi Zingwe za QuickPen Syringe * onani chithunzi 3 .

Kukongoletsa Mtundu wa Dzu Lobatani - onani chithunzi 2 .

Kugwiritsa ntchito cholembera

Tsatirani malangizo awa kuti mumalize jakisoni aliyense.

1. Kukonzekera kwa Syninge Yachangu

Kokani kapu ya cholembera kuti muchotse. Osazungulira kapu. Osachotsa cholembera ku cholembera.

Onetsetsani kuti mwayang'ana insulini yanu:

Tsiku lotha ntchito

Chidwi: Nthawi zonse werengani cholembera cholembera kuti onetsetsani kuti mukugwiritsa ntchito mtundu woyenera wa insulin.

Kwa kuyimitsidwa kwa insulin kokha:

Lungunulani cholembera maulendo 10 pakati pama manja anu

tembenuza cholembera maulendo 10.

Kusakaniza ndikofunikira kuti mukhale otsimikiza kuti mupeze mlingo woyenera. Insulin iyenera kuwoneka yosakanikirana.

Tengani singano yatsopano.

Chotsani chomata papepala ndi singano yakunja.

Gwiritsani ntchito swab wothira mowa kuti mupukutire disc ya mphira kumapeto kwa cholembera.

Valani singano mu cap kulondola pamphepete mwa cholembera.

Skani pa singano kufikira mutalumikizidwa kwathunthu.

2. Kuyang'ana cholembera cha QuickPen Syringe cholembera Insulin

Chenjezo: Ngati simukuyang'ana insulin musanadye jakisoni iliyonse, mutha kutsika kwambiri kapena kutsika kwambiri ndi insulin.

Chotsani singano yakunja. Osataya.

Chotsani thumba lamkati la singano ndikuitaya.

Khazikitsani magulu awiri mutembenuza batani la mlingo.

Lowetsani cholembera.

Dinani pazosungira cartridge kuti mulole mpweya kuti utuluke

Ndi singano ikuloza, kanikizani batani la mlingo mpaka litayime ndipo nambala ya "0" ipezekere pazenera.

Gwiritsani ntchito batani la muyeso poti mwaweleranso ndipo muwerenge pang'onopang'ono mpaka 5.

Kutsimikizira kwa insulin kudya kumawerengedwa ngati kumatha kuyipa kwa insulin kumapeto kwa singano.

Ngati phula la insulin silikuwoneka kumapeto kwa singano, ndiye kuti mubwereze njira zomwe mungayang'anirenso insulin kanayi, kuyambira pa point 2B ndikutha ndi point 2G.

Chidziwitso: Ngati simukuwona kupsinjika kwa insulin ikuwoneka kuchokera ku singano, ndikuyika mankhwalawo kumakhala kovuta, ndiye kuti siyani ndi singanoyo ndikubwereza kuyang'ana kuchuluka kwa insulini kuchokera mu cholembera.

Sinthani batani la mlingo kuti mupeze chiwerengero chomwe mukufuna jakisoni.

Ngati mwayika magulu ambiri mwangozi, mutha kuwongolera uthengawo mosinthanitsa ndi batani lolowanalo.

Ikani singano pansi pa khungu pogwiritsa ntchito jakisoni yemwe dokotala wanu wakupatsani.

Ikani chala chanu pa batani la mlingo ndikulimbikira batani la mlingo mpaka litayima kwathunthu.

Kuti mulowetse mlingo wathunthu, gwiritsani batani la mlingo ndikuwerengerani pang'onopang'ono mpaka 5.

Chotsani singano pansi pa khungu.

Zindikirani : Yang'anani ndikuonetsetsa kuti mukuwona nambala ya "0" pazenera la dokotala, kuti muwonetsetse kuti mwalowa muyezo wonse.

Ikani chotseka chakunja pa singano.

Chidziwitso: Chotsani singano pambuyo pa jekeseni aliyense kuti muchepetse thovu m'malembedwe.

Osasunga cholembera ndi singano yake.

Tulutsani singano ndi chophimba chakunja ndikuitaya mogwirizana ndi malangizo a dokotala.

Ikani chipewa pa syringe cholembera, chikugwirizana ndi cholumikizira cholumikizira ndi chisonyezo cha kukoka ndi kukankhira cap mwachindunji mu axis pa cholembera.

Kuwonetsa magawo 10 (onani chithunzi 4) .

Ngakhale manambala amasindikizidwa muwindo la chizindikiro ngati manambala, manambala osamvetseka amasindikizidwa ngati mizere yolunjika pakati pa manambala.

Chidziwitso: Cholembera sichingakuloreni kukhazikitsa kuchuluka kwa mayunitsi mopitilira kuchuluka kwa zigawo zomwe zatsala mu cholembera.

Ngati simukutsimikiza kuti mwapereka mlingo wonse, musamaperekenso mankhwala ena.

Kukopa pa kuthekera kuyendetsa ma transp. Wed Ndi ubweya:

Pa hypoglycemia, wodwalayo amatha kuchepa ndende komanso kuthamanga kwa zochitika zama psychomotor. Izi zitha kukhala zowopsa nthawi zomwe maluso amenewa amafunikira makamaka (mwachitsanzo, kuyendetsa magalimoto kapena makina ogwiritsa ntchito).

Odwala ayenera kulangizidwa kuti azisamala popewa hypoglycemia poyendetsa magalimoto.Izi ndizofunikira kwambiri kwa odwala omwe ali ndi zofatsa kapena zosapezekapo zizindikiro, okhazikika a hypoglycemia kapena kukula pafupipafupi kwa hypoglycemia. Zikatero, adotolo amayenera kuwunika momwe magalimoto amayendera.

Kuyimitsidwa kwa kayendetsedwe ka subcutaneous, 100 IU / ml.

10 ml ya mankhwalawa osalowa mugalasi Mbale. Botolo 1 limodzi ndi malangizo ogwiritsira ntchito mankhwalawa amaikidwa pakatoni.

3 ml pa cartridge imodzi yandale. Makatoni asanu amayikidwa mu chithuza. Chithuza chimodzi limodzi ndi malangizo ogwiritsira ntchito zimayikidwa pakatoni.

Kapenanso bokosilo limakhazikika mu cholembera cha QuickPen tm. Ma syringe asanu pamodzi ndi malangizo ogwiritsira ntchito ndi malangizo ogwiritsira ntchito cholembera amaphatikizidwa mukatoni.

Kutentha kwa 2 mpaka 8 ° C. Kuteteza ku dzuwa mwachindunji ndi kutentha. Osalola kuzizira.

Chithandizo chachiwiri Sungani kutentha kwa chipinda - kuyambira 15 mpaka 25 ° C osaposa masiku 28.

Pewani kufikira ana.

Osagwiritsa ntchito tsiku lanu litatha.

Zoyenera kugawidwa kuchokera ku malo ogulitsa mankhwala: Nambala Yalembetsa

Malangizo omaliza opanga 14.09.2016

Algorithm yokhudza makulidwe a insulin Humulin NPH

• Humulin mumbale mu mbale musanagwiritse ntchito uyenera kusakanizidwa ndikulowetsa vial pakati pa kanjedza mpaka khungu la mkaka litawonekera. Osagwedezeka, thovu, kapena kugwiritsa ntchito insulin yotsalira pamakoma a vial.
• Humulin NPH m'makatiriji osati kungosuntha pakati pa manja, kubwereza kayendedwe ka 10, komanso kusakaniza, mofatsa kutembenuza bokosi. Onetsetsani kuti insulin ndi yoyenera kuyendetsedwa poyang'anira kusasinthasintha ndi mtundu. Payenera kukhala zofanana pamtundu wa mkaka. Komanso musagwedeze kapena kufumba mankhwala. Osagwiritsa ntchito yankho ndi phala kapena phala. Ma insulin ena sangayikiridwe katiriji ndipo sangathe kudzazidwanso.
• Cholembera cha syringe chili ndi 3 ml ya insulin-isophan pa mlingo wa 100 IU / ml. Pa jakisoni 1, lowetsani osaposa 60 IU. Chipangizocho chimalola dosing ndi kulondola kwa 1 IU. Onetsetsani kuti singano ndiyomatirira pachidacho.

Sambani manja pogwiritsa ntchito sopo ndikuwachiza ndi antiseptic.

Sankhani malo a jakisoni ndikuchiza khungu ndi yankho la antiseptic.

Masamba obayira enanso kuti malo omwewo sawagwiritsanso ntchito kamodzi pamwezi.

Zomwe zimagwiritsidwa ntchito pa cholembera cha syringe

1. Chotsani kapu poikoka m'malo mozunguliza.
2. Onani insulin, moyo wa alumali, kapangidwe kake ndi mtundu wake.
3. Konzani singano ya syringe monga tafotokozera pamwambapa.
4. Pukuta singano mpaka itakhala yolimba.
5. Chotsani zisoti ziwiri ku singano. Kunja - osataya.
6. Onani kuchuluka kwa insulin.
7. Pindani khungu ndikubaya singano pansi pakhungu pakona kwama degree 45.
8. Yambitsani insulini pogwira batani ndi chala chanu mpaka chitayima, kuwerengetsa pang'onopang'ono m'maganizo mpaka 5.
9. Mukachotsa singano, ikani nyemba za mowa pamalo a jekeseni osapaka kapena kupwanya khungu. Nthawi zambiri, dontho la insulin limatha kukhalabe kumapeto kwa singano, koma osatulutsa, zomwe zikutanthauza kuti mlingo wosakwanira.
10. Tsekani singano ndi kapu yakunja ndikuitaya.

Kuyanjana kwina ndi mankhwala ena

Mankhwala omwe amalimbikitsa Humulin:

• mapiritsi ochepetsa shuga,
• antidepressants - monoamine oxidase inhibitors,
• Hypotonic mankhwala ochokera pagulu la ACE zoletsa ndi beta blockers,
• kaboni anhydrase zoletsa,
• imidazoles
• tetracycline mankhwala opha tizilombo,
• Kukonzekera kwa lifiyamu
• Mavitamini B,
• theofylline
• mankhwala okhala ndi zakumwa zoledzeretsa.

Mankhwala omwe amalepheretsa insulin Humulin NPH:

• mapiritsi olembera
• glucocorticosteroids,
• mahomoni a chithokomiro,
• okodzetsa
• mankhwala antidepressants,
• othandizira omwe amachititsa kuti mitsempha ichite chisoni,
• calcium blockers,
• narcotic analgesics.

Humulin Wokhazikika

Zimatanthauzira ma insulin afupiafupi. Imayamba kugwira ntchito theka la ola pambuyo pa kayendetsedwe (jakisoni amapatsidwa mphindi 15-30 musanadye), imafika pazowonjezera pambuyo pa maola 1.5-3, imakhala ndi zotsalira za glycemia kwa maola 5-7.

Mankhwalawa ndi oyenera kulipira odwala omwe amatsatira njira yoyerekeza, powerengera pafupifupi tsiku lililonse. Ndikulimbikitsidwa kupukusidwa poyambitsidwa ndi matenda omwe ali ndi shuga. Imalekereredwa bwino ndi okalamba, komanso odwala onse omwe matenda awo amakumana ndi matenda oyanjana.

Nthawi zambiri, mankhwala a insulin a Humulin pafupipafupi amayamba pakukonzekera kwa odwala kuti achitidwe opaleshoni yayikulu kapena panthawi ya matenda opweteka kwambiri. Monga lamulo, zotsatira zabwino zamankhwala zimakhala zofunikira kwambiri pakukhazikitsa njira zochiritsirazi ngakhale atatsimikizira njira zochizira.

Mndandanda wapamwamba wotere nthawi zambiri umakhala ndi zovuta zoyipa, umalekerera mosavuta. Kupezeka kwa lipodystrophy nthawi zambiri kumalumikizidwa ndi kuyambitsa kwa malangizowo, ndipo hypoglycemia imangowoneka chifukwa cha kuchuluka kwa mankhwala. Kusintha kwa Humulin pafupipafupi kuyenera kuchitika kokha moyang'aniridwa ndi dokotala woyenera, popeza kusintha kwakukulu kwa chizolowezi chamankhwala a insulin kungakhale kofunikira. Njira yabwino ndiyo kusankha kwa mankhwalawa mu chipatala chapadera.

Kuwonjezeka / kuchepa kwa chiwerengero cha jakisoni ndi kuchuluka kwawo kumatha kuchitika motsutsana ndi maziko a kupsinjika, matenda, zolimbitsa thupi. Chofunikanso kwambiri ndi malo omwe amasankhidwa kuti apakidwe jakisoni, chidwi chamunthu chogwira ntchito.

Amagwiranso ntchito pa gulu la analogues ya nthawi yayitali. Zimasiyana ndi kuyamba kwakanthawi kovutirapo, chifukwa mkati mwa ola limodzi (nthawi zina mphindi zokwanira 30) mutalowa pakhungu, umayamba kugwira ntchito bwino, kutalika kumachitika pambuyo pa maola 1.5-8, kukhalabe m'thupi mpaka maola 15. Imayendetsedwa kokha subcutaneously / intramuscularly!

Kuyimitsidwa kumakhala ndi 30% Humulin pafupipafupi, ena onse amagwera Humulin NPH . Kusintha mawonekedwe a mankhwalawa, ndikofunikira kuti zitsatire momwe munthu angachitire ndi kusintha kwa jakisoni, kuwonjezera / kuchepetsa nthawi pakati pakabayidwa ndi zakudya.

Kugwiritsa ntchito mankhwalawa kumafuna kuti wodwalayo asunge mosamala malamulo osungira ndi kutsata insulin iyi. Asanagwiritse ntchito, botolo liyenera kukukhidwira pakati pa manja (pafupifupi nthawi 10) kuti lisakanikidwe. Mapangidwe omalizidwa ayenera kukhala ndi mtundu wonyezimira (wamkali), wophatikizika.

Kuti tikwaniritse zabwino, nthawi zambiri pamakhala masiku atatu, makonzedwe azakudya amasankhidwa, mtundu wonsewo umasinthidwa kuti uziwonetsetse momwe timagwirira timadzi tambiri.

Zokonzekera zonse za wopanga zimasungidwa mufiriji mpaka kutsegulidwa. Mukayamba kugwiritsa ntchito, vial iyenera kusungidwa kutentha. Kuzizira kumapangitsa kuti mankhwalawo akhale othandiza. Moyo wa alumali wa analog otseguka ndi masabata 4 okha.

Zolembera za syringe zimagwiritsidwa ntchito chimodzimodzi monga (Humapen, Humapen Luxura) . Kugwiritsa ntchito ma syringe otayika ndikololedwa.

Kumbukirani, njira zilizonse zochizira endocrine pathologies zitha kugwiritsidwa ntchito mutakambirana ndi adokotala! Kudzipatsa nokha mankhwala kukhala koopsa.

Wopanga: Eli Lilly, Eli Lilly

Mutu: Humulin NPH ®, Humulin NPH ®

Zopangidwa: 1 ml muli yogwira insulin 100 IU. Omwe amathandizira: m-Cresol wosungunuka 1.6 mg / ml, glycerol, phenol 0.65 mg / ml, protamine sulfate, dibasic sodium phosphate, zinc oxide, madzi a jakisoni, hydrochloric acid, sodium hydroxide.

Machitidwe Humulin NPH ndi insulin yomwe ikukonzekera. Kukhazikika kwa mankhwala ndi ola limodzi pambuyo pa kuperekedwa, mphamvu yayitali imakhala pakati pa maola awiri ndi asanu ndi atatu, kutalika kwa zochitika ndi maola 18-20. Kusiyana kwa zochitika za insulin zimadalira zinthu monga mlingo, kusankha jakisoni, malo olimbitsa thupi.

Zisonyezero zogwiritsidwa ntchito: Mtundu woyamba wa matenda ashuga a mtundu wachiwiri mtundu 2 matenda oopsa a shuga )

Njira yogwiritsira ntchito: Mankhwala ayenera kuperekedwa sc, mwina / m kuyambitsa. Mu / pakubweretsa Humulin NPH ndi yotsutsana! Mankhwala a SC amaperekedwa paphewa, ntchafu, matako kapena pamimba. Tsamba la jakisoni liyenera kusinthidwa kuti malo omwewo asagwiritsidwerenso kuposa mwezi umodzi. Mukamayambitsa mawuwo, chisamaliro chikuyenera kuyambidwa kuti musalowe mumtsempha wamagazi. Pambuyo pa jakisoni, tsamba la jakisidwe siliyenera kutenthedwa.

• Zotsatira zoyipa zomwe zimakhudzana ndi zotsatira zazikulu za mankhwalawa: hypoglycemia.
• Hypoglycemia kwambiri ikhoza kuyambitsa kusokonezeka kwa chikumbumtima ndipo (mwapadera) kufa.
• Thupi lawo siligwirizana: zimachitika matupi awo sagwirizana - hyperemia, kutupa kapena kuyunkhira pamalo a jekeseni (nthawi zambiri amayima patadutsa masiku angapo mpaka masabata angapo), kayendedwe ka ziwalo (zimachitika kawirikawiri, koma zimakhala zowopsa) - kuyamwa kambiri, kufupika, kupuma pang'ono , kuchepa kwa magazi, kuchuluka kwa mtima, kuchuluka thukuta. Milandu yambiri yokhudzana ndimomwe thupi limagwirira ntchito ikhoza kukhala pachiwopsezo cha moyo.
• Zina: mwayi wokhala ndi lipodystrophy ndizochepa.

Zoyipa: Hypoglycemia. Hypersensitivity kupita ku insulin kapena chimodzi mwazinthu za mankhwala.

Zochita Zamankhwala: Mphamvu ya hypoglycemic ya Humulin NPH imachepetsedwa ndi kulera kwapakamwa, corticosteroids, kukonzekera kwa mahomoni a chithokomiro, thiazide diuretics, diazoxide, tridclic antidepressants.

Mphamvu ya hypoglycemic ya Humulin NPH imapangidwira ndi mankhwala amkamwa a hypoglycemic, salicylates (mwachitsanzo acetylsalicylic acid), sulfonamides, MAO zoletsa, beta-blockers, ethanol ndi ethanol okhala ndi mankhwala.

Beta-blockers, clonidine, reserpine amatha kuphimba mawonetseredwe a zizindikiro za hypoglycemia.

Mimba ndi kuyamwa: Pakati pa nthawi yayitali, ndikofunikira kuti pakhale chitetezo chabwino cha glycemic mwa odwala matenda ashuga. Pa nthawi ya pakati, kufunika kwa insulin nthawi zambiri kumachepetsa mu trimester yoyamba ndikuwonjezeka trimesters yachiwiri ndi yachitatu.

Odwala omwe ali ndi matenda a shuga mellitus pa mkaka wa m`mawere, kusintha kwa insulin, zakudya, kapena zonse ziwiri zingafunike.

Pakufufuza koopsa kwa majini mu vitro komanso mndandanda wa vivo, insulin yaumunthu idalibe mutagenic.

Malo osungira: Mankhwalawa amayenera kusungidwa mufiriji kutentha kwa 2 ° mpaka 8 ° C, kupewa kuzizira, kuteteza ku kuyatsidwa mwachindunji. Moyo wa alumali ndi zaka 2.

Mankhwala omwe amagwiritsidwa ntchito mu vial kapena katiriji amayenera kusungidwa kutentha kwambiri (15 ° mpaka 25 ° C) osaposa masiku 28.

Chosankha: Kusamutsa wodwala kupita ku mtundu wina wa insulin kapena kukonzekera kwa insulin ndi dzina lina lamalonda kuyenera kuchitika moyang'aniridwa ndi achipatala. Zosintha mu zochitika za insulin, mtundu wake (mwachitsanzo, pafupipafupi, M3), mitundu (porcine, insulin ya anthu, analogue ya insulin) kapena njira yopanga (DNA recombinant insulin kapena insulin ya chiyambi cha nyama) zitha kuchititsa kusintha kwa mlingo.

Kufunika kwa kusintha kwa mankhwalawa kungafunike kale pokhazikitsidwa ndi insulin yokonzekera pambuyo pokonzekera insulin ya nyama kapena pang'onopang'ono milungu ingapo kapena miyezi ingapo atasamutsidwa.

Ku Russia, anthu pafupifupi 3 miliyoni ochokera ku dziko lonselo akudwala matenda opatsirana padziko lonse lapansi - matenda ashuga. Nthawi zambiri, anthu odwala matenda ashuga nthawi zambiri amapita ku endocrinologists ndikudziyimira pawokha magazi. Chiwerengero chikuwonjezereka tsiku ndi tsiku, ndipo tsiku lililonse matendawa amalembedwa mwa anthu 200, ndipo 90% yamatenda a shuga.

Mu magawo oyamba, mankhwala amkamwa amagwiritsidwa ntchito kuti achepetse shuga, ndipo chithandizo cha insulin chimatha. Mwa njira, nthawi zambiri chithandizo cha insulin chimayamba mochedwa kwambiri, ngakhale pali mankhwala ambiri okhala ndi mankhwalawa. Mwambiri, mu mawonekedwe a jakisoni, amatha kugawidwa m'magulu atatu.

1. Ma insulini amunthu:

• kopitilira muyeso kochepa
• zochita zazifupi
• nthawi yayitali yochita.

1. Mafuta a insulin yaumunthu:

• kuchitapo kanthu kwa nthawi yayitali.

1. Zosakaniza:

• zochita zosakanikirana (analogue + human),
• zosakanikirana za sing'anga ndi zazifupi akuchita insulin.

Kukonzekera kumapangidwa ndi makampani osiyanasiyana, ndipo ndi dokotala yekha yemwe ayenera kusankha yoyenera. Palibe chifukwa chake musalowe m'malo mankhwalawo, chifukwa izi zitha kupangitsa kuti thupi liziganiza mosasamala, chifukwa cha kuchuluka kwa mankhwala omwe sanasinthe. Ngakhale gawo laling'ono lothandizanso lingathe kuyambitsa mavuto ambiri. Othandizira angapo a protamine Hagedorn omwe satchulidwa pagome amayimira mankhwala omwe amagwiritsidwa ntchito kwambiri ku Russia.

Humulin insulin yochizira matenda ashuga mwa akulu, ana ndi pakati. Humulin Nph: malangizo ogwiritsira ntchito

Ku Russia, anthu pafupifupi 3 miliyoni ochokera ku dziko lonselo akudwala matenda opatsirana padziko lonse lapansi - matenda ashuga. Nthawi zambiri, anthu odwala matenda ashuga nthawi zambiri amapita ku endocrinologists ndikudziyimira pawokha magazi. Chiwerengero chikuwonjezereka tsiku ndi tsiku, ndipo tsiku lililonse matendawa amalembedwa mwa anthu 200, ndipo 90% yamatenda a shuga.

Mu magawo oyamba, mankhwala amkamwa amagwiritsidwa ntchito kuti achepetse shuga, ndipo chithandizo cha insulin chimatha. Mwa njira, nthawi zambiri chithandizo cha insulin chimayamba mochedwa kwambiri, ngakhale pali mankhwala ambiri okhala ndi mankhwalawa. Mwambiri, mu mawonekedwe a jakisoni, amatha kugawidwa m'magulu atatu.

1. Ma insulini amunthu:

• kopitilira muyeso kochepa
• zochita zazifupi
• nthawi yayitali yochita.

1. Mafuta a insulin yaumunthu:

• kuchitapo kanthu kwa nthawi yayitali.

1. Zosakaniza:

• zochita zosakanikirana (analogue + human),
• zosakanikirana za sing'anga ndi zazifupi akuchita insulin.

Kukonzekera kumapangidwa ndi makampani osiyanasiyana, ndipo ndi dokotala yekha yemwe ayenera kusankha yoyenera. Palibe chifukwa chake musalowe m'malo mankhwalawo, chifukwa izi zitha kupangitsa kuti thupi liziganiza mosasamala, chifukwa cha kuchuluka kwa mankhwala omwe sanasinthe. Ngakhale gawo laling'ono lothandizanso lingathe kuyambitsa mavuto ambiri. Othandizira angapo a protamine Hagedorn omwe satchulidwa pagome amayimira mankhwala omwe amagwiritsidwa ntchito kwambiri ku Russia.

Wopanga

Yopangidwa ndi: Eli Lilly ndi Company, USA. Lilly Corporate Center, Indianapolis, Indiana 46285, USA.

Cartridges, QuickPen ™ Syringe Pens , yopangidwa ndi Lilly France, France. Zone Industrialiel, 2 ru Colonel Lilly, 67640 Fegersheim, France.

Atanyamula: ZAO "ORTAT", 157092, Russia, dera la Kostroma, chigawo cha Susaninsky, s. Kumpoto, microdistrict. Kharitonovo.

Lilly Pharma LLC ndiye mlendo yekha wa Humulin ® NPH ku Russian Federation.

Mankhwala Humulin NPH amafotokozera malangizo ogwiritsira ntchito ngati mankhwala a matenda ashuga.Imagwira m'malo mwa insulin mwa anthu omwe ali ndi matenda a kapamba. Humulin amatchulidwa ndi dokotala yemwe alibe vutoli m'thupi. Momwe mungamwere mankhwala?

Sizingagwiritsidwe ntchito liti?

Pali zotsutsana zochepa pakugwiritsira ntchito Humulin. Izi zimaphatikizapo: hypoglycemia, yomwe imakhazikitsidwa musanamwe mankhwalawo, komanso chidwi cha anthu pazigawo zake. Choyipa chachikulu ndi hypoglycemia, yomwe imatha kukomoka komanso ngakhale kufa, koma zotsatira zoyipa ndizosowa kwambiri.

Zotsatira zina zoyipa:

Nthawi zina kuwonetseredwa kwanuko kumatha kuchitika, monga hyperemia, edema. Ngati bongo umachitika, zotsatirazi zimachitika thupi:

Hypoglycemia iyenera kuyang'aniridwa mosamala, monga momwe zinthu zina zingasinthire. Kuti muthane ndi matenda ofatsa, mutha kumwa shuga pang'ono. Kenako, muyenera kusintha zakudya ndi zakudya, komanso masewera olimbitsa thupi. Ndi avareji ya hypoglycemia, glucagon imayendetsedwa mu mawonekedwe a jakisoni ndipo pakamwa kudya zakudya zamthupi kumachitika. A kwambiri mawonekedwe a matendawa amatha kudziwika ndi chikomokere, kukomoka, kusokonezeka kwamanjenje.

Momwe mungagwiritsire ntchito mankhwalawa?

Mlingo wa Humulin uyenera kusankhidwa mosiyanasiyana. Mankhwala sangathe kutumikiridwa kudzera m'mitsempha. Njira yodziwika kwambiri ya kulowetsedwa imakhala pansi pa khungu, nthawi zina intramuscularly. Kwa subcutaneous makonzedwe, dera la m'chiuno, matako, phewa, ndi m'mimba ndilabwino. Pakatha mwezi umodzi, m'malo amodzi simungathe kupanga jakisoni wopitilira 1. Popeza maluso ena amafunikira pobayira jakisoni wa mankhwalawo, ndibwino kuperekera njira izi kwa omwe akuchita chithandizo chamankhwala poyamba. Mukapereka mankhwalawa, ndikofunikira kuti musalowe m'mitsempha osati kupaka jakisoni.

Musanagwiritse ntchito, makatoni ndi mabotolo amayenera kugududwa kanthawi khumi m'manja mwanu ndikugwedezeka kuti kuyimitsidwa kukhala matte kapena mtundu pafupi ndi mkaka. Ndizosatheka kugwedeza zomwe zili mumbale za mbale kwambiri, chifukwa chithovu chotsatira chimapangitsa kuti zikhale zovuta kudziwa mulingo woyenera. Pokonzekera insulin, muyenera kupenda mosamala zomwe zili m'mapulogalamuwa. Ngati zotupa, zotumphukira zoyera, mawonekedwe omwe ali pamakoma ngati chisanu amawonekera mmenemo, mankhwalawa sangathe kugwiritsidwa ntchito.

Kuti mupeze jakisoni, ndikofunikira kutenga syringe ya voliyumu yomwe ikufanana ndi mlingo wofunikira. Pambuyo pa njirayi, tikulimbikitsidwa kuti muwononge singano ndikutseka chogwiritsa ntchito chipewa. Izi ndizofunikira kuti tisungidwe osasokoneza mankhwalawa, kuti tipewe kutsekeka kwa zinthu zakunja ndi mpweya kulowa. Osagwiritsa ntchito singano kapena syringe kachiwiri. Sungani mankhwalawo pamalo abwino amdima. Mukayamba kugwiritsa ntchito, botolo limatha kusungidwa osaposa mwezi umodzi.

Ndi kuyambitsa kwa Humulin NPH, mawonekedwe ena ogwiritsira ntchito akuyenera kuganiziridwa:

• kudalira insulin wodwala kumachepa ngati impso, adrenal, pituitary, chithokomiro, chiwindi, ntchito
• Pamavuto, wodwala amafunanso insulin yambiri,
• Kusintha kwa mankhwalawa ndikofunikira posintha zakudya kapena mukamachita masewera olimbitsa thupi,
• ziwengo zomwe zimapezeka mwa wodwala sizingakhale zokhudzana ndi insulin.
• Nthawi zina kumayambiriro kwa mankhwalawa kungafune kuthandizidwa mwadzidzidzi.

Chifukwa cha chiwopsezo cha kukhala ndi hypoglycemia pambuyo pa jekeseni, munthu ayenera kupewa magalimoto oyendetsa ndi makina ogwiritsira ntchito.

Kuchita bwino kwa mankhwalawa kumachepetsedwa ngati kulera kwapakamlomo, mahomoni a chithokomiro, antidepressants, diuretics, glucocorticoids amatengedwa limodzi. Mphamvu ya mankhwalawa imalimbikitsidwa ngati mumamwa nthawi yomweyo:

• Mowa
• hypoglycemic mankhwala,
• salicylates,
• beta adenoblockers,
• sulfonamides,
• Mao zoletsa.

Clonidine ndi reserpine zimatha kupereka zizindikiro za hypoglycemia.

Analogi ndi mitengo

Mtengo wapakati pa paketi ya Humulin NPH umasiyana pakati pa ma ruble 1000.Popeza mankhwalawa palibe, mungagwiritse ntchito fanizo limodzi. Izi ndi:

1. Mwadzidzidzi insulin-Ferein. M'mapangidwe ake mumakhala insulin yopanga ya anthu. Mankhwalawa amapezeka mu njira yothetsera jakisoni wa subcutaneous.
2. Monotard NM. Mankhwala ndi a gulu la insulin ndi pafupifupi nthawi ya kuchitapo, amapezeka mwa kuyimitsidwa kwa 10 ml botolo.
3. Humodar B. Muli insulin yaumunthu, imapezekanso mu 100 IU mu 1 ml.
4. Pensulin SS ndi analogue ina yopanga nthawi yayitali.

Mwa zina mwa Humulin NPH pali:

Pharmacology yamakono ali okonzeka kupereka chisankho chachikulu cha insulin yokonzekera odwala matenda ashuga. Komabe, chifukwa chosiyana pakapangidwe kake komanso nthawi yomwe akuchitapo kanthu, katswiri wodziwa bwino yekha ndi amene ayenera kusankha analogue a mankhwala omwe adakhazikitsidwa, ndikuwonetsetsa kuti mulingo wake ndi uti.

Ndemanga za Odwala

Odwala ambiri amalabadira mosiyanasiyana pokonzekera insulin. Makamaka, Humulin NPH samayambitsa zovuta, ngakhale malangizo ogwiritsa ntchito amachenjeza za iwo. Insulin yochokera ku mankhwalawa imamwetsedwa bwino ngati mulingo amawerengedwa molondola ndipo jakisoni adapangidwa moyenera. Zomwe zimangoyambitsa zovuta zitha kukhala zosagwirizana ndi zomwe dokotala wanena kapena jakisoni wolakwika wa namwino kapena wodwalayo. Kuti mupewe izi, muyenera kuyandikira mosamala momwe mungagwiritsire ntchito mankhwalawa. Njira yokhayo yopewa bongo ndi zotsatira zoyipa.

Humulin NPH ndi kukonzekera kwa insulini kuchokera ku gulu la mankhwala othandizira nthawi yayitali. Dokotala wokha amene amathandizira wodwala matenda a shuga ayenera kupereka mankhwala. Njira izi zikuthandizira kupewa bongo, chisankho cholakwika cha analogue komanso kuwerengetsa voliyumu yomwe wodwala amafunikira. Dokotala amathanso kuganizira zofunikira zapadera zomwe angagwiritse ntchito ndi zotsutsana ndi wodwala, zomwe zimapewe kuyipa kwa mankhwalawa.

Zikomo chifukwa cha ndemanga yanu.

Ndemanga

Megan92 () masabata 2 apitawo

Kodi pali amene wakwanitsa kuchiza matenda ashuga? Amati ndizosatheka kuchiritsa kwathunthu.

Daria () masabata 2 apitawo

Ndinaonanso kuti sizingatheke, koma nditawerenga nkhaniyi, ndidayiwaliratu za matenda "osachiritsika" awa.

Megan92 () masiku 13 apitawa

Daria () masiku 12 apitawo

Megan92, kotero ndidalemba mu ndemanga yanga yoyamba) Chitani izi molingana ndi - ulalo wa nkhani.

Sonya masiku 10 apitawo

Koma kodi uku si kusudzulana? Chifukwa chiyani akugulitsa pa intaneti?

Yulek26 (Tver) masiku 10 apitawo

Sonya, mukukhala m'dziko liti? Amagulitsa pa intaneti, chifukwa masitolo ndi mafakitala amaika chizindikiro chawo. Kuphatikiza apo, kulipira kokha atalandira, ndiko kuti, ankayang'ana koyamba, kufufuzidwa kenako ndi kulipira. Inde, ndipo tsopano amagulitsa chilichonse pa intaneti - kuchokera ku zovala kupita kuma TV ndi mipando.

Kuyankha Kwa mkonzi masiku 10 apitawa

Sonya, moni. Mankhwalawa othandizira matenda osokoneza bongo a shuga samagulitsika kudzera pa intaneti ya mankhwala kuti asawonongeke kwambiri. Mpaka pano, mutha kuyitanitsa pa tsamba lovomerezeka. Khalani athanzi!

Sonya masiku 10 apitawo

Pepani, poyamba sindinazindikire zambiri zandalama. Kenako chilichonse ndichabwino, ngati mwalandira mukalandira.

Malangizo apadera ogwiritsa ntchito

Mankhwala amayenera kutumizidwa ndi adokotala okha. Chokani ku pharmacies ndi mankhwala. Pochita mankhwala ndi Humulin NPH, kuwunika pafupipafupi kuchuluka kwa shuga kumafunika. Pamaso pa matenda ophatikizika - funsani dokotala kuti musinthe mlingo.

Insulin yopanga ma genetic imapangitsa kuti zitheke kukwaniritsa zotsatira zazikulu pakuwongolera matenda a shuga kwa odwala omwe ali ndi matenda amtundu wa 1, amayi apakati ndi amayi oyamwitsa, odwala omwe amapezeka ndi matenda a shuga a 2, ngakhale motsutsana ndi maziko a insulin kapena osagwiritsa ntchito mankhwalawa.

Kuchita kwa analogue kumayambira ola limodzi pambuyo pothandizidwa ndi ma subcutaneous, kumatha pafupifupi maola 16 mpaka 20 ndikufika pamlingo wokwanira maola 4-8.Kupezeka kwa nsonga ya kuchitapo kanthu kumathetsa mankhwalawa, koma zovuta izi zimayendetsedwa mosavuta mothandizidwa ndi zakudya zosankhidwa bwino, kutsatira dongosolo la tsiku ndi tsiku, ndikukonzekera mokwanira zolimbitsa thupi.

Nthawi zambiri, timadzi timene timagwiritsidwa ntchito nthawi 1-2 patsiku, kutengera mtundu wa glycemia, chidwi cha munthu pa mankhwalawo. Amaloledwa kusakaniza mankhwalawo (ngakhale jakisoni imodzi) ndi mapikisano ofupikirako a omwewo, motero kuchepetsa kuchuluka kwa jakisoni patsiku.

Mlingo

Ndi kuyimitsidwa kawiri kapena chisakanizo:

Mankhwala a Insulle Insulin 30%

Kuyimitsidwa kwa Isofan Human Insulin 70%

Omwe amathandizira: dist-m-cresol (1.6 mg / ml), glycerol, phenol (0.65 mg / ml), protamine sulfate, dibasic sodium phosphate, zinc oxide, madzi d / u, hydrochloric acid, sodium hydroxide.

Odwala Apadera ndi Mayendedwe

Popereka Humulin, adokotala ayenera kuganizira kuti odwala ena amafunikira chithandizo chapadera. Thupi lawo, mankhwalawa amatha kuthana ndi vuto ngati simukuwonetsa kuchenjera.

Izi zikugwiranso ntchito kwa odwala monga:

1. Amayi oyembekezera. Mankhwala awo ndi mankhwalawa amaloledwa, chifukwa insulini siyivulaza kukula kwa mwana wosabadwayo ndipo sikuti kuphwanya njira yoyembekezera. Koma pakadali pano, azimayi amadziwika ndi kusintha kwakukuru m'mazira a shuga, ndichifukwa chake kusinthika kwakukulu pamlingo wakusowa kwa thupi kwa insulin ndikotheka. Kulephera kuyendetsa bwino kungayambitse bongo ndipo, zomwe zimakhala zowopsa kwa mayi woyembekezera komanso mwana. Chifukwa chake, ndikofunikira kuyang'ana kuchuluka kwa shuga m'mimba yonse.
2. Amayi adayamwitsidwa. Amaloledwa kugwiritsa ntchito Humulin. Zomwe zimagwiritsidwa ntchito sizikhudza mtundu wa mkaka wa m'mawere ndipo sizowopseza khanda. Koma muyenera kuwonetsetsa kuti mzimayi amatsata chakudya.
3. Ana. Ngati muli ndi matenda ashuga ali ana, mutha kugwiritsa ntchito mankhwala okhala ndi insulin. Koma muyenera kuganizira za zomwe zimachitika mthupi, chifukwa chake muyenera kusankha mlingo wa mankhwalawa.
4. Anthu okalamba. Amakhalanso ndi zochitika zokhudzana ndi zaka zomwe zimadaliridwira kuti musamalire mukamapereka Humulin ndikusankha dongosolo la mankhwala. Koma ndi njira yoyenera, mankhwalawa samavulaza odwala.

Izi zikutanthauza kuti kuti muthandizidwe ndi insulini muyenera kuyang'aniridwa ndi dokotala nthawi zonse ndikuzindikira zinthu zonse zomwe zingakhudze thanzi.

Chofunikira popereka mankhwala ndikuti mupeze matenda omwe amadziwika ndi odwala kuwonjezera pa matenda a shuga. Chifukwa cha iwo, kusintha kwa dongosolo la mankhwala ndi kusintha kwa mankhwala kungafunike.

Izi zikugwiranso ntchito pa milandu yotsatirayi:

1. Kukhalapo kwa kulephera kwa impso. Chifukwa cha ichi, kufunikira kwa insulini kumakhala kotsika kuposa zovuta zotere. Izi zikutanthauza kuti odwala matenda ashuga omwe ali ndi vuto la impso amakhala ndi mankhwala ochepetsera.
2. Kulephera kwa chiwindi. Ndi matenda awa, kuthekera kwa Humulin pamthupi kungakhale. Mwakutero, madokotala amayesetsa kuchepetsa kuchuluka kwa mankhwalawa.

Chifukwa cha Humulin, palibe mavuto okhudzana ndi chidwi ndi chidwi, kotero, ntchito iliyonse imaloledwa pa mankhwala ndi mankhwalawa. Chenjezo liyenera kuchitika pamene hypoglycemia ichitika, chifukwa chovuta m'dera lino. Izi zimatha kutenga chiwopsezo chovulala mukamachita zoopsa ndikupanga ngozi zoyendetsa.

Contraindication

Hypersensitivity kupita ku insulin kapena chimodzi mwazinthu za mankhwala.

Momwe mungadziwire kuperewera kwa glucose komanso kupereka thandizo kwa omwe akukhudzidwayo

Anapulumutsa anthu masauzande ambiri ndipo anasintha mbiri

Mutha kufunsa funso lililonse lomwe muli nalo pazogulitsa kapena sitolo.

Akatswiri athu oyenerera angakuthandizeni.

Kutumiza kovomerezeka

Imachitika mkati mwa maola atatu kuyambira nthawi yoyitanitsa ndipo imawononga ma ruble 300.

Mutha kunyamula nokha oda yanu komanso kwaulere, mu pharmacy ku adilesi: 41 Mitinskaya Street, Moscow.

Malo osankha amakhala otseguka tsiku lililonse kuyambira 10:00 mpaka 21:00. Onetsetsani kuti mukugwirizana nthawi yanu yakubwera ndi wothandizira!

• Ma oda omwe adalandilidwa pambuyo pa 20:00 amaperekedwa tsiku lotsatira,
• Tikuyang'ana kuti ngati oda yanu idalandilidwa kuyambira 21:00 mpaka 9:00, imathandizidwa ndi ogwiritsa ntchito athu pokhapokha 9:00,
• "Kutumiza" - sizitanthauza ntchito yoyendetsedwa ndi lamulo. Zogulitsazo sizibwera ndi antchito a mankhwala. Sitolo yapaintaneti iyi siyomwe ilipo chifukwa cha zomwe amachita. Ndalama yobweretsera si ndalama zolipirira, koma mawonekedwe othokoza kwa wothandizira amene wabweretsa kugula,
• Pakuvomereza kuti kuperekedwa ndikololedwa kwa inu ndi lamulo la Russian Federation, mukutsimikizira kuti mwazidziwa nokha chikalatachi pamtundu wokonda nzika ndipo mukutsimikiza kuti zomwe muli nazo zikugwirizana ndi zomwe zafotokozedwa mu Article 2 ya Federal Law of Russian Federation ya 09.01.1997 No. 5-FZ ndi kwa onse oyenda pa Order of Labor Glory ”(monga momwe zidasinthidwira pa Julayi 2, 2013) ndi Article 1.1 ya Law of the Russian Federation yomwe ili pa 01.15.1993 No. 4301-1" Pa Status of Heroes of the Soviet Union, Heroes of the Russian Federation and Full Knights of the Order of Glory ".

Takhazikitsa BoxkaRu kuti ikhale yabwino.

Kusankha ndi kugula mankhwala oyenera tsopano ndikosavuta. Lamula mankhwalawa ndipo tidzakupatsani. Tili ndi gawo lalikulu komanso ntchito yabwino, yomwe sitikukayikira kuti mungayamikire. Tikutsimikizira zabwino zokhazokha kuchokera kwa ogulitsa wamkulu azamankhwala pamitengo yotsika kwambiri.

Zikomo chifukwa chokhala nafe!

Zambiri, TabletRu

Zofananira za mankhwala a humulin m3 zimaperekedwa, molingana ndi terminology yachipatala, yotchedwa "ma syonyms" - mankhwala osinthika omwe ali ndi chinthu chimodzi kapena zingapo zomwe zimagwira ntchito molingana ndi zomwe zimachitika mthupi. Mukamasankha mawu ofananitsa, osangoganizira mtengo wawo, komanso dziko lakapangidwe ndi mbiri ya wopanga.

Mndandanda wazofananira

Tcherani khutu! Mndandandandawu umakhala ndi mawu ofanana a Humulin M3, omwe ali ndi mawonekedwe ofanana, kotero mutha kusankha nokha m'malo mwake, mukuganizira mawonekedwe ndi mankhwalawa omwe mankhwalawo adauzidwa ndi adokotala. Perekani zokonda kwa opanga ku USA, Japan, Western Europe, komanso makampani odziwika bwino ochokera ku Eastern Europe: Krka, Gideon Richter, Actavis, Aegis, Lek, Hexal, Teva, Zentiva.

Alendo makumi awiri adanenapo zakudya za tsiku ndi tsiku

Kodi ndiyenera kumwa Humulin M3 kangati?
Ambiri omwe amayankhidwa amamwa mankhwalawa kawiri pa tsiku. Ripotilo likuwonetsa kuti anthu ena omwe amayankha mankhwalawa amamwa kangati

Alendo khumi ndi atatu ananenanso za kumwa

Alendo awiri adalengeza zakwaniritsidwa

Humulin M3 imatenga nthawi yayitali bwanji kuti athe kumva kukhudzidwa kwa wodwalayo?
Ochita kafukufukuwo nthawi zambiri atatha tsiku limodzi adasintha. Koma izi sizingafanane ndi nthawi yomwe musinthe. Funsani dokotala wanu kuti mupeze mankhwalawa kwa nthawi yayitali bwanji. Gome ili pansipa likuwonetsa zotsatira za kafukufuku pa zoyambira kuchitapo kanthu.

Alendo atatu adanena nthawi yolandila alendo

Nthawi yabwino kutenga Humulin M3: pamimba yopanda kanthu, isanachitike, itatha, kapena ndi chakudya?
Ogwiritsa ntchito patsamba ambiri nthawi zambiri amati amamwa mankhwalawa asanadye. Komabe, adotolo atha kuvomereza nthawi ina. Ripotilo likuwonetsa pamene ena onse omwe adawafunsidwa amamwa mankhwalawo.

Mimba komanso kuyamwa

Zomwe zili patsamba lino zinatsimikiziridwa ndi katswiri wazachipatala Vasilieva E.I.

Munthu wobwerezabweretsanso insulin ya DNA.

Kukonzekera: HUMULIN ® M3
Chithandizo chogwira ntchito: munthu wa insulin
Code ya ATX: A10AD01
KFG: Insulin Yapakatikati Yapakati pa Anthu
Reg. nambala: P No. 013713/01
Tsiku lolembetsa: 01/19/06
Mwini reg. Degree: ELI LILLY VOSTOK S.A.

FOMU YA DOSAGE, KULIMA NDI KUSANGALATSA