Kubwereza kwa lantus

Lantus ndi insulin-kutsitsa insulin kukonzekera. Yogwira ntchito ya lantus ndi insulin glargine - analogue ya insulin ya anthu, yosungunuka bwino m'malo osagwirizana nawo.

Pokonzekera Lantus, thunthu limasungunuka kwathunthu chifukwa cha sing'anga yapadera, ndipo pakayendetsedwe koyambira, asidi amalephera ndipo microprecipitates imapangidwa, pomwe insulin glargine imatulutsidwa pang'onopang'ono. Chifukwa chake, m'madzi a m'magazi mulibe kusintha kwenikweni kwa insulin, koma mawonekedwe osunthika a mawonekedwe a nthawi ya ndende amawonedwa. Microprecipitate imapereka mankhwala kwa nthawi yayitali.

Zochita zamankhwala

Gawo logwira la lantus limakhala ndi ubale wa insulin receptors ofanana ndi kuyanjana ndi insulin ya anthu. Glargine imamangiriza kwa insulin receptor IGF-1 5-8 nthawi yamphamvu kuposa insulin yaumunthu, ndipo ma metabolites ake amakhala ofooka.

Kuphatikizira kwazowonjezera zomwe zimapangidwira gawo la insulin ndi metabolites yake m'magazi a odwala omwe ali ndi vuto la 1 shuga mellitus ndizochepa kuposa zofunikira kuti zitsimikizire kulumikizana kwapakati ndi IGF-1 receptors ndikuwonjezera kupititsa kwa mitogen-proliferative limagwidwa ndi receptor iyi.

Njira imeneyi nthawi zambiri imayendetsedwa ndi amkati IGF-1, koma njira zochizira za insulin zomwe zimagwiritsidwa ntchito mu insulin mankhwala ndizotsika kwambiri kuposa kutsimikizika kwa pharmacological kofunikira kuyambitsa makina kudzera IGF-1.

Ntchito yayikulu ya insulin iliyonse, kuphatikiza glargine, ndikuwongolera kwa glucose metabolism (carbohydrate metabolism). Insulin lantus imathandizira kudya shuga ndi adipose ndi minofu minofu, chifukwa chomwe shuga ya plasma imachepa. Komanso, mankhwalawa amalepheretsa kupanga shuga m'magazi.

Insulin imayambitsa kaphatikizidwe kazakudya zomanga thupi mthupi, pomwe tikulepheretsa njira za proteinolysis ndi lipolysis mu adipocytes.

Kafukufuku wa zamankhwala ndi zamankhwala adawonetsa kuti akaperekedwa ndi mtsempha wa magazi, mulingo wofanana wa insulin glargine ndi insulin ya anthu ndi ofanana. Kuchita kwa insulin glargine pakapita nthawi, monga oimira ena pamndandanda uno, kumadalira zochitika zolimbitsa thupi komanso zinthu zina zambiri.

Ndi subcutaneous makonzedwe, mankhwalawa Lantus amatenga pang'onopang'ono, kotero kuti amatha kugwiritsidwa ntchito kamodzi patsiku. Ndikofunika kukumbukira kuti pali kutanthauzira kosiyanasiyana kwamtundu umodzi muzochitika za insulin pakapita nthawi. Kafukufuku awonetsa kuti mphamvu ya diabetesic retinopathy ilibe kusiyana kwakukulu mukamagwiritsa ntchito insulin glargine ndi insulin NPH.

Pogwiritsa ntchito Lantus mwa ana ndi achinyamata, kukula kwa nocturnal hypoglycemia kumayang'aniridwa pafupipafupi kuposa gulu la odwala lomwe limalandira NPH insulin.

Mosiyana ndi insulin NPH, glargine chifukwa cha kuyamwa pang'onopang'ono sizimayambitsa kukwera pambuyo pakukhazikitsa. The kuchuluka kwa ndende ya mankhwala mu madzi am`magazi zimawonedwa pa 2 - 4th tsiku la mankhwala ndi limodzi tsiku makonzedwe. Hafu ya moyo wa insulin glargine pamene kutumikiridwa m`thupi limafanana ndi nthawi yofanana ya insulin yaumunthu.

Ndi kagayidwe ka insulin glargine, mapangidwe awiri opanga M1 ndi M2 amachitika. Jekeseni wa subcutaneous wa Lantus amakhala ndi zotsatira zawo makamaka chifukwa cha kuwonetseredwa kwa M1, ndipo M2 ndi insulin glargine sizipezeka mu maphunziro ambiri.

Kugwiritsa ntchito kwa mankhwala Lantus ndi chimodzimodzi m'magulu osiyanasiyana odwala. M'kati mwa kafukufukuyu, ma subgroups adapangidwa ndi zaka komanso jenda, ndipo zotsatira za insulin mwa iwo zinali zofanana ndi anthu ambiri (malinga ndi mphamvu ndi chitetezo). Mwa ana ndi achinyamata, maphunziro a pharmacokinetics sanachitike.

Zizindikiro zogwiritsidwa ntchito

Lantus amatumizidwa kuchiza matenda a shuga omwe amadalira odwala ndi ana opitirira zaka zisanu ndi chimodzi.

Mankhwalawa amagwiritsidwa ntchito poika mankhwalawa, amaletsedwa kuyikha intra. Kukhalitsa kwa mphamvu ya lantus kumalumikizidwa ndi kuyambitsa kwake mu mafuta ochepa.

Ndikofunika kwambiri kuti musaiwale kuti kudzera mu mtsempha wa mafupa a mankhwalawa, mankhwalawa amatha kuyamba. Mukamagwiritsa ntchito mankhwalawa, malamulo angapo amayenera kuonedwa:

Munthawi yamankhwala, muyenera kutsatira njira inayake ndikuti jakisoni moyenera.
Mutha kulowa mankhwalawo m'mimba, komanso mu ntchafu kapena minofu yolumikizika. Palibe kusiyana kwakanthawi kachipembedzo ndi njira izi.
Jekeseni iliyonse imayendetsedwa bwino pamalo atsopano mkati mwa malo omwe analimbikitsidwa.
Simungathe kubereka Lantus kapena kusakaniza ndi mankhwala ena.

Lantus ndi insulin yokhala nthawi yayitali, choncho iyenera kuperekedwa kamodzi patsiku, makamaka nthawi imodzi. Mlingo wofunikira wa munthu aliyense amasankhidwa payekha, komanso mlingo ndi nthawi yoyang'anira.

Ndizovomerezeka kupereka mankhwala Lantus kwa odwala omwe ali ndi vuto la matenda a shuga 2 limodzi ndi antidiabetesic othandizira pakamwa.

Ndikofunikira kudziwa kuti magawo a zochita za mankhwalawa ndi osiyana ndi zigawo zina za mankhwala ena omwe ali ndi insulin.

Odwala okalamba amafunika kusintha mlingo, chifukwa amatha kuchepa kwa insulin chifukwa cha kuwonongeka kwa impso. Komanso, mwa odwala omwe ali ndi vuto la chiwindi, kufunika kwa insulin kumatha kuchepa. Izi ndichifukwa choti insulin metabolism imachepetsa, ndipo gluconeogeneis imachepetsedwa.

Kusintha ku Lantus ndi mitundu ina ya insulin

Ngati munthu adagwiritsapo kale ntchito mankhwala osokoneza bongo a nthawi yayitali komanso yayitali, ndiye kuti akusintha kupita ku Lantus, ayenera kusintha mawonekedwe a inulin, komanso kuwunikiranso njira zina zamankhwala.

Kuchepetsa chiopsezo cha hypoglycemia m'mawa ndi usiku, posintha makonzedwe awiri a basal insulin (NPH) kukhala jakisoni imodzi (Lantus), mlingo wa basal insulin uyenera kuchepetsedwa ndi 20-30% masiku makumi awiri oyamba. Ndipo mlingo wa insulin wothandizidwa pokhudzana ndi chakudya ufunika kuwonjezeka pang'ono. Pakatha milungu iwiri kapena itatu, kusintha kwa mlingo kuyenera kuchitidwa payekhapayekha kwa wodwala aliyense.

Ngati wodwalayo ali ndi antibodies ku insulin ya anthu, ndiye kuti mukamagwiritsa ntchito Lantus, mayankho a thupi kusintha majakisoni a insulin, omwe angafunenso kuwunikiridwa kwa mlingo. Zimafunikanso pakusintha moyo wamunthu, kusintha thupi kapena zina zomwe zimakhudza momwe machitidwe a mankhwala aliri.

Lantus wa mankhwalawa amayenera kuperekedwa kokha pogwiritsa ntchito zolembera za OptiPen Pro1 kapena ClickSTAR syringe. Musanayambe kugwiritsa ntchito, muyenera kuphunzira mosamala malangizo a cholembera ndikutsatira malangizo onse omwe akupanga. Malamulo ena ogwiritsa ntchito zolembera:

Ngati chigwacho chaphwanyidwa, ndiye kuti muyenera kutaya ndi kugwiritsidwa ntchito chatsopano.
Ngati ndi kotheka, mankhwala ochokera ku cartridge amatha kuperekedwa ndi syringe yapadera ya insulin yokhala ndi mayunitsi a 100 ml.
Katoniyo amayenera kusungidwa kutentha kwa maola angapo asanayikidwe mu cholembera.
Mutha kugwiritsa ntchito makatiriji okhawo omwe mawonekedwe a yankho sanasinthe, mtundu wake ndikuwonekera, palibe kuwongolera konse komwe kumawonekera.
Musanalowetse yankho mu katiriji, onetsetsani kuti mumachotsa thovu (momwe mungachitire izi, amalembedwa malangizo a cholembera).
Makatoni othandizira ndi oletsedwa.
Pofuna kupewa mwadzidzidzi insulini ina m'malo mwa glargine, ndikofunikira kuyang'ana pa jekeseni iliyonse.

Zotsatira zoyipa

Nthawi zambiri, odwala ndi osafunika chifukwa ntchito mankhwala Lantus ndi hypoglycemia. Amayamba ngati mankhwalawa amaperekedwa pa mlingo wopitirira womwe umafunikira wodwalayo. Zotsatira zotsatirazi zingayambenso kuyambitsidwa kwa Lantus:

Kuchokera ziwalo zam'maganizo ndi zamanjenje - dysgeusia, kuwonongeka mu kuwona kwamphamvu, retinopathy,
pakhungu, komanso minyewa yodutsa - lipohypertrophy ndi lipoatrophy,
hypoglycemia (kagayidwe kachakudya),
mawonekedwe a matupi awo - edema ndi redness khungu pakhungu, urticaria, anaphylactic mantha, bronchospasm, edi Quincke,
Kuchedwa kwa ayoni ayoni m'thupi, kupweteka kwa minofu.

Tiyenera kukumbukira kuti ngati hypoglycemia imakula pafupipafupi, ndiye kuti chiopsezo chokhala ndi mavuto mu ntchito yamanjenje ndi chambiri. Hypoglycemia yomwe imakhalapo kwa nthawi yayitali ndi yoopsa ku moyo wa wodwalayo.

Pochiza ndi insulin, ma antibodies amatha kupanga mankhwala.

Mwa ana ndi achinyamata, zovuta zosafunikira monga kupweteka kwa minofu, kuwonetsa matupi awo, kupweteka kwa malo a jakisoni kumatha kukhala pa mankhwala a Lantus. Mwambiri, kwa akulu ndi ana onse, chitetezo cha Lantus chili pamodzimodzi.

Contraindication

Lantus sayenera kutumizidwa kwa odwala omwe ali ndi vuto la mankhwala kapena othandizira pazinthu, komanso anthu omwe ali ndi hypoglycemia.

Mwa ana, Lantus amatha kutumikiridwa pokhapokha akafika zaka zisanu ndi chimodzi kapena kupitirira.

Monga mankhwala osankhidwa pochiza matenda a shuga a ketoacidosis, mankhwalawa sanalembedwe.

Ndikofunikira kugwiritsa ntchito Lantus mosamala kwambiri mwa odwala omwe ali ndi chiopsezo chathanzi nthawi ya hypoglycemia ikachitika, makamaka kwa odwala omwe amachepetsa ziwalo zamatumbo kapena zotupa zowonjezereka, malangizo akuwunikira.

Ndikofunikira kusamala kwambiri ndi odwala omwe mawonetsedwe awo a hypoglycemia amatha kuphimbidwa, mwachitsanzo, ndi autonomic neuropathy, kusokonezeka kwa m'maganizo, kukula kwapang'onopang'ono kwa hypoglycemia, komanso kuphunzira kwa nthawi yayitali matenda ashuga. M'pofunikanso kupereka Lantus mosamala kwa anthu achikulire ndi odwala omwe anasintha ku insulin ya anthu kuchokera ku mankhwala ochokera kwanyama.

Mukamagwiritsa ntchito Lantus, muyenera kuyang'anira mosamala muyezo wa anthu omwe ali pachiwopsezo chachikulu cha kukhala ndi hypoglycemia yayikulu. Izi zitha kuchitika:

kukulitsa chidwi cha maselo ku insulin, mwachitsanzo, pakuchotsa zinthu zomwe zimayambitsa kupsinjika,
kulimbitsa thupi kwambiri,
kusanza ndi kusanza
Zakudya zopanda mafuta, kuphatikiza kudya zakudya,
kumwa mowa
kuperekera mankhwala munthawi yomweyo.

Mankhwala a Lantus, ndibwino kuti musamachite nawo zinthu zina zofunika kuchita chisamaliro, chifukwa hypoglycemia (monga hyperglycemia) imatha kupangitsa kuchepa kwa maonedwe ndi chidwi.

Lantus ndi pakati

Mwa amayi apakati, palibe maphunziro azachipatala a mankhwalawa omwe adachitika. Zambiri zidapezeka pokhapokha pakutsatsa malonda (pafupifupi 400 - 1000 milandu), ndipo akuwonetsa kuti insulin glargine ilibe vuto lililonse pakubala komanso kukula kwa mwana.

Kuyesa kwanyama kwawonetsa kuti insulin glargine ilibe vuto lililonse kwa mwana wosabadwayo ndipo siyikuwononga kwambiri kubereka.

Amayi oyembekezera Lantus amatha kutumizidwa ndi dokotala ngati kuli kofunikira. Ndikofunika kuyang'anitsitsa kuchuluka kwa shuga ndikuchita zonse kuti pakhale kuchuluka kwa shuga m'magazi a amayi apakati, komanso kuwunika momwe mayi woyembekezera akuyembekezerera panthawi ya bere. Mu trimester yoyamba, kufunika kwa insulin kumatha kuchepa, ndipo m'nthawi yachiwiri ndi yachitatu, makulidwe. Mwana akangobadwa kumene, kufunikira kwa thupi kwa zinthu izi kumatsika kwambiri ndipo hypoglycemia imayamba.

Ndi mkaka wa m`mawere, ntchito Lantus amathanso kuyang'aniridwa mosamala pa mlingo wa mankhwalawa. Akamamwa m'matumbo am'mimba, insulin glargine imagawika ma amino acid ndipo sichimupweteketsa mwana pakuyamwa. Malangizo omwe glargine amadutsa mkaka wa m'mawere, malangizo mulibe.

Kuchita ndi mankhwala ena

Ndi munthawi yomweyo kugwiritsa ntchito mankhwala Lantus ndi njira zina zomwe zimakhudza kagayidwe kazakudya, kusintha kwa mankhwalawa ndikofunikira.

Kuchepetsa mphamvu ya insulin kumapangitsanso mankhwala a shuga am'mkamwa, angiotensin-kutembenuza mphamvu zoletsa, disopyramides, fibrate, monoamine oxidase inhibitors, fluoxetine, pentoxifylline, salicylates, propoxyphene, sulfonamides.

Mphamvu ya hypoglycemic ya Lantus imachepetsedwa ndi zochita za danazol, diazoxide, corticosteroids, glucagon, diuretics, estrogens ndi progestins, somatotropin, sympathomimetics, isoniazid, phenothiazine zotumphukira, olanzapine, proteinase inhibitors, clozapine.

Mankhwala ena, monga clonidine, beta-blockers, lithiamu ndi ethanol, onse amatha kukulitsa ndikuchepetsa mphamvu ya Lantus.

Malangizo ogwiritsira ntchito munthawi yomweyo mankhwalawa ndi pentamidine amawonetsa kuti hypoglycemia imayamba kuchitika, yomwe pambuyo pake imakhala hyperglycemia.

Bongo

Mlingo wambiri wa mankhwala Lantus amatha kupweteka kwambiri, kwa nthawi yayitali komanso koopsa, komwe ndi kowopsa paumoyo komanso wodwala. Ngati mankhwala osokoneza bongo sanafotokozeredwe bwino, amatha kuyimitsidwa pogwiritsa ntchito chakudya.

Panthawi yomwe hypoglycemia imayamba, wodwala ayenera kusintha moyo wake ndikusintha mlingo womwe umayenera kugwiritsidwa ntchito.

Ngati hypoglycemia imadziwoneka bwino kwambiri, motsatana ndi kukhudzika, kusintha kwamitsempha, ndiye kuti glucagon iyenera kuperekedwa mwachangu kapena kudzera mu intramuscularly kapena jakisoni wofunsira wa njira yayikulu ya shuga. Mwa njira, mkhalidwewo uli ndi mawonekedwe owopsa kwambiri, ndipo zizindikiro za chikomokere mu hypoglycemic, ndipo ndi izi, muyenera kudziwa.

Tiyenera kukumbukira kuti mankhwalawa Lantus amakhala ndi mphamvu yayitali, choncho ngakhale mkhalidwe wa wodwalayo wasintha, muyenera kupitiliza kumwa mankhwala kwa nthawi yayitali ndikuyang'anira momwe thupi liliri.

Malo osungira

Moyo wa alumali wa Lantus ndi zaka 3, nthawi ino ndi yoyenera kugwiritsidwa ntchito, kutentha kwa boma kuyenera kusungidwa mkati mwa 2 - 8 digiri Celsius. Sizoletsedwa kumasula yankho. Mukatsegula cartridge iyenera kusungidwa kutentha kwa 15 - 25 digiri. Alumali moyo wa mankhwala otseguka si wopitilira mwezi umodzi.

Mu 1 ml ya Lantus yankho lili:

3.6378 mg wa insulin glargine (izi ndi zofanana ndi magawo zana a glargine),
othandizira othandizira.

Makatoni amodzi ndi mankhwalawa ali ndi magawo 300 a insulin glargine ndi zina zowonjezera.

Malangizo ogwiritsira ntchito

Chitani izi kamodzi patsiku nthawi yomweyo. Pakuphatikiza jakisoni mankhwala sikuletsedwa. Popewa lipodystrophy, sinthani malo a jakisoni.

Sikulimbikitsidwa kuti muchepetse kapena kusakaniza Lantus ndi mankhwala ena a insulin. Izi zitha kubweretsa kusintha mu pharmacodynamics ya glargine.

Kusankhidwa kwa Mlingo kumafunika posintha kulemera kwa wodwalayo kapena moyo wake. Komanso kuchuluka kwa mankhwalawa kumatengera nthawi yomwe amayambitsa.

Zotsatira zoyipa

Zotsatira zoyipa zakumwa za mankhwala ndi hypoglycemia. Zimayambitsa kuchuluka kwakukulu kwa mankhwala omwe ali ndi zosowa za odwala matenda ashuga.Mkhalidwe wam'tsogolo umayambitsidwa ndi zizindikiro monga tachycardia, thukuta kwambiri, njala, mantha, kusakwiya, khungu la khungu. Hypoglycemia imawonetsedwa ndi zizindikiro zotsatirazi:

mavuto amawonedwe
kukokana
kutopa ndi kutopa,
mutu
kuchepa kwakukulu kwa ndende,
kusanza ndi kusanza.

Kuukira kwa nthawi yayitali komanso pafupipafupi kumapangitsa kuti mantha awonongeke. Nthawi zina chimapha.

Zomwe zimachitika kawirikawiri kwa Insulin Lantus ndizomwe zimayambitsa ziwengo. Amadziwika ndi edema, zotupa pakhungu, ochepa hypotension, kapena bronchospasm. Nthawi zina, insulin imayamba chifukwa cha maonekedwe a ma antibodies oyenera m'thupi la wodwalayo.

Zotsatira zina zoyipa zimaphatikizidwa ndi kusokoneza kwa kukoma, matenda ashuga retinopathy, myalgia, lipoatrophy, ndi lipodystrophy. Edema, ululu, redness, ndi kuyabwa kumachitika pamalo a jakisoni. Pakapita kanthawi kochepa, zizindikirazi zimazimiririka zokha.

Mimba komanso kuyamwa

Odwala ayenera kudziwitsa dokotala za mimba yomwe ilipo kapena yakonzekera.

Panalibe mayesero azachipatala omwe amayesedwa mwachisawawa pakugwiritsa ntchito insulin glargine mwa amayi apakati.

Chiwerengero chochulukirapo (zotsatira zopitilira 1000 za kubereka komanso zotsatirazi) ndikutsatsa pambuyo pake kugwiritsidwa ntchito kwa insulin glargine kunawonetsa kuti sanakhale ndi zotsatila zake pa maphunzirowa komanso zotsatira za mimba kapena chikhalidwe cha mwana wosabadwa.

Kuphatikiza apo, pofuna kuyesa chitetezo cha insulin glargine ndi insulin-isophan ntchito kwa amayi apakati omwe ali ndi vuto lakale kapena gestational matenda osokoneza bongo, kuwunika kwa meta-kuyesedwa kwa mayesero asanu ndi atatu a kuchipatala kunachitika, kuphatikiza azimayi omwe amagwiritsa ntchito insulin glargine pa nthawi yoyembekezera (n = 331) ndi insulin isophane (n = 371).

Kuunika kwa meta kumeneku sikunawonetse kusiyana kwakukulu pokhudza chitetezo cha mayi kapena mwana wakhanda pogwiritsa ntchito insulin glargine ndi insulin-isophan panthawi yapakati.

M'maphunziro a zinyama, palibe deta yachindunji kapena yosalunjika yomwe idapezeka pa embryotoxic kapena fetotoxic zotsatira za insulin glargine.

Kwa odwala omwe ali ndi matenda osokoneza bongo omwe alipo kale kapena a gestationalabetes mellitus, ndikofunikira kuti pakhale malamulo oyendetsera kagayidwe kachakudya kameneka panthawi yonse yoyembekezera kuti pakhale zovuta zomwe zikubwera ndi hyperglycemia.

Mankhwala Lantus® SoloStar® angagwiritsidwe ntchito pa nthawi ya pakati pazifukwa zamankhwala.

Kufunika kwa insulini kumatha kuchepa mu trimester yoyamba ya kubereka, komanso, kuwonjezeka panthawi yachiwiri komanso yachitatu.

Pambuyo pobadwa, kufunika kwa insulini kumachepera msanga (chiopsezo cha hypoglycemia chikuwonjezeka). Pansi pa izi, kuwunikira mosamala kuchuluka kwa shuga m'magazi ndikofunikira.

Odwala pa mkaka wa m`mawere angafunikire kusintha Mlingo wa insulin ndi zakudya.

M'maphunziro a zinyama, palibe deta yachindunji kapena yosalunjika yomwe idapezeka pa embryotoxic kapena fetotoxic zotsatira za insulin glargine.

Mpaka pano, palibe ziwerengero zoyenera zogwiritsira ntchito mankhwalawa panthawi yapakati. Pali umboni wa kugwiritsa ntchito kwa Lantus mwa azimayi 100 oyembekezera omwe ali ndi matenda ashuga. Maphunziridwe ake ndi zotsatira za kutenga pakati pa odwalawa sizinasiyanane ndi zomwe zimachitika mwa amayi apakati omwe ali ndi matenda ashuga omwe amalandiranso kukonzekera kwina kwa insulin.

Kukhazikitsidwa kwa Lantus mwa amayi apakati kuyenera kuchitika mosamala. Kwa odwala omwe ali ndi matenda osokoneza bongo omwe alipo kale kapena a gestationalabetes mellitus, ndikofunikira kuti azitha kuyang'anira machitidwe a metabolic panthawi yonse yovomerezeka.

Kufunika kwa insulin kumatha kuchepa mu trimester yoyamba ya kutenga pakati ndikuwonjezeka panthawi yachiwiri komanso yachitatu. Pambuyo pobadwa, kufunika kwa insulini kumachepera msanga (chiopsezo cha hypoglycemia chikuwonjezeka).

Pansi pa izi, kuyang'anira shuga wamagazi ndikofunikira.

Mwa kuyamwa azimayi, mlingo wa insulini komanso kusintha kwa zakudya kungafunike.

Zotsatira zoyipa za mankhwalawa pa thupi la amayi apakati komanso mwana wosabadwa sizitsimikiziridwa ndi maphunziro azachipatala. Komabe, azimayi omwe ali ndi pakati pa nthawi yobereka ayenera kumwa mankhwalawa mosamala kwambiri, ndikuyang'anira mosamala madokotala omwe akupita.

Ngakhale akumamwa mankhwalawa, amayi apakati amafunika kuyesa magazi pafupipafupi kuti awone kuchuluka kwa shuga mthupi. Miyezi itatu yoyambirira ya kubereka, kufunikira kwa insulin kumatha kuchepetsedwa, koma mu 2nd ndi 3 trimester imatha kuchuluka. Pambuyo pobadwa kwa mwana, kufunikira kwa mankhwalawa kumacheperanso, komwe kumalumikizidwa ndi kusintha kwa mahomoni.

Mimba

Amayi oyembekezera pokhapokha pakufunika. Ndikofunika kuyang'anitsitsa kuchuluka kwa shuga m'magazi ndikuwunika momwe mayi wapakati amakhalira. M'miyezi itatu yoyambirira, kufunikira kwa insulin kumachepa, ndipo miyezi isanu ndi umodzi yotsatira imadzuka. Mukangopereka kumene, kufunika kwa chinthu ichi kumatsika kwambiri. Pali chiopsezo cha hypoglycemia.

Ndi mkaka wa m`mawere, kumwa mankhwala n`zotheka, koma mosamala kuwunika. Glargin imalowetsedwa m'matumbo am'mimba ndikugawika ma amino acid. Zilibe kuvulaza mwana poyamwitsa.

Kusintha kupita ku Lantus kuchokera ku mitundu ina ya insulin

Ngati wodwalayo adamwa kale mankhwala osokoneza bongo nthawi yayitali, ndiye kuti akusintha kupita ku Lantus, kusintha kwa insulin yayikulu ndikofunikira. Thercomitant tiba iyeneranso kuwunikiridwa.

Pamene jakisoni awiri wa basal insulin (NPH) asinthidwa kukhala jakisoni imodzi ya Lantus, mlingo woyamba umatsika ndi 20-30%. Izi zimachitika masiku 20 oyambirira a mankhwala. Izi zikuthandizira kupewa hypoglycemia usiku ndi m'mawa. Pankhaniyi, mlingo womwe umaperekedwa musanadye chakudya umakulitsidwa. Pambuyo pa masabata 2-3, kukonza kwa kuchuluka kwa zinthu kumachitika palokha kwa wodwala aliyense.

Mthupi la odwala ena, ma antibodies a insulin yaumunthu amapangidwa. Pankhaniyi, mayankho omenyera chitetezo ku majakisidwe a Lantus amasintha. Kungafunikenso kuunikiridwa mlingo.

Moyo wa alumali ndi kufanana

Sungani mankhwalawo pamalo otetezedwa ndi dzuwa. Ulamuliro wabwino wotentha ndi +2 ... +8 ° C. Kuzizira sikuvomerezeka. M'pofunikanso kupewa kulumikizana ndi chidebe ndi yankho la chakudya chowundana ndi mufiriji. Mukamasula cholembera, imatha kusungidwa kwa masabata 4 pa kutentha kwakukulu kwa +25 ° C.

Mndandanda waukulu wa mankhwalawo ndi Insulin Levemir. Wopanga ndi Novo Nordisk. Imachepetsa shuga m'magazi.

Insulin Lantus ndi yoyenera pafupifupi magulu onse odwala. Mankhwalawa amatengera mtundu woyenera wa insulin ndipo umakhala wokhazikika pazochita zake.

Zimakhala ndi chiyani

Chopanga chachikulu chomwe chimakhala ndi mphamvu ya mankhwalawa ndi insulin glargine. Mu 1 ml ya Lantus Solostar muli pafupifupi 3.6 mg ya chinthu ichi - ndende iyi ndiofanana ndi 100 IU ya insulin ya anthu.

Kuphatikizikako kumaphatikizapo zinthu zingapo zothandiza, cholinga chake ndikuwonjezera kupezeka kwa Solostar, kuchepetsa kuchepa kwa thupi. Izi ndi monga zinthu:

Zink chloride.
M-cresol.
Sodium hydroxide.
Glycerol.
Hydrochloric acid.
Madzi a jakisoni.

Lantus Solostar imapezeka mu cholembera chomwe chingagwiritsidwe ntchito popanda kukonzekera mwapadera. Cholembera chilichonse chimakhala ndi kuchuluka kwa kuchuluka kwa zinthu zomwe zimagwira, zikamaliza, chipangizocho chimangotaya ndikugula chatsopano. Njira yabwino kwa odwala matenda ashuga ndi mankhwala omwe amapezeka mu njira ya Opti-Click: amatha kugwiritsidwa ntchito nthawi zambiri - ngati insulin mu cartridge itatha, ndiye kuti imangosinthidwa.

Palinso mankhwala ena ofanana - insulin Tujeo Solostar. Ili ndi glargine yochulukirapo, mu 1 ml zomwe zimakhala ndikufika pa 10,9 mg, zomwe zimafanana ndi 300 PISCES ya insulin yaumunthu. Kusiyanitsa kwakukulu pakati pa mankhwalawa ndi Lantus ndikuti, poyerekeza ndi lachiwiri, limatenga nthawi yayitali - mpaka maola 24.

Mwa zina za Lantus, Humalog ndi Biosulin amagwiritsidwa ntchito nthawi zambiri. Yoyamba imayimiriridwa ndi insulin lispro yogwira ntchito mu 100 IU pa millilita. Lachiwiri ndi mainjiniya a chibadwidwe cha anthu omwe amakhala mumagawo omwewo. Pakati pazosiyana, chinthu chachikulu ndikuti mankhwalawa pamwambapa amagwira ntchito mwachidule, choncho amafunikira kugwiritsidwa ntchito kangapo patsiku.

Imodzi mwa fanizo za Solostar Humalog.

Momwe mungagwiritsire ntchito mankhwala

Mankhwala amagwiritsidwa ntchito pa matenda a shuga, omwe amafunikira chithandizo ndi insulin. Nthawi zambiri imakhala mtundu woyamba wa shuga. Hormoni imatha kutumizidwa kwa odwala onse azaka zopitilira zisanu ndi chimodzi.

Kuchita insulin kwa nthawi yayitali ndikofunikira kuti magazi a wodwalayo azisala mwachangu. Munthu wathanzi m'magazi nthawi zonse amakhala ndi kuchuluka kwa mahomoni awa, zomwe zimakhala m'magazi zimatchedwa basal level. Odwala omwe ali ndi matenda a shuga mellitus ngati ali ndi vuto la kapamba, pakufunika insulin, yomwe imayenera kuperekedwa nthawi zonse.

Njira ina yotulutsira mahomoni m'magazi imatchedwa bolus. Zimaphatikizidwa ndi kudya - poyankha kuwonjezeka kwa shuga wamagazi, insulini ina imatulutsidwa kuti mwachangu matenda a glycemia ayambe kudwala. Mu shuga mellitus, ma insulin osakhalitsa amagwiritsidwa ntchito pamenepa. Pankhaniyi, wodwalayo amayenera kudziphatikiza ndi cholembera nthawi iliyonse atatha kudya, zomwe zimakhala ndi kuchuluka kwa mahomoni.

M'mafakitala, kuchuluka kwa mitundu yosiyanasiyana ya mankhwala othandizira matenda a shuga amagulitsidwa. Ngati wodwala akufunika kugwiritsa ntchito timadzi tambiri tomwe timapanga, ndiye kuti ndi bwino kugwiritsa ntchito - Lantus kapena Levemir? Munjira zambiri, mankhwalawa ndi ofanana - onse ndi ofunika, ndi olosera kwambiri komanso osasunthika pakugwiritsa ntchito.

Tiyeni tiwone momwe mahomoni awa amasiyanirana. Amakhulupilira kuti Levemir ali ndi moyo wautali kwambiri kuposa Lantus Solostar - mpaka masabata 6 motsutsana ndi mwezi umodzi. Chifukwa chake, Levemir amadziwika kuti ndiwothandiza kwambiri ngati mukufunikira kuti mupeze mankhwala ochepa, mwachitsanzo, kutsatira zakudya zamagulu ochepa.

Akatswiri akuti Lantus Solostar angakulitse chiopsezo cha khansa, koma palibe chodalirika pazomwezi.

Musagwiritse ntchito mankhwala atha!

Momwe mungagwiritsire ntchito chida

Tisanthula momwe tingagwiritsire ntchito Lantus - malangizo oti agwiritse ntchito akuti ayenera kulowetsedwa mosavomerezeka m'matumbo a mafuta pakhoma lakumbuyo, ndipo sangathe kugwiritsidwa ntchito kudzera m'mitsempha. Njira iyi yogwiritsira ntchito mankhwalawa idzatsogolera kutsika kwakukulu kwamagazi a glucose ndikukula kwa chikumbumtima cha hypoglycemic.

Kuphatikiza pa CHIKWANGWANI pamimba, pali malo ena oyambitsira a Lantus - minofu yachikazi, yachikazi. Kusintha kwake muzochitika izi ndizosafunikira kapena kulibe. Homoni sangaphatikizidwe pamodzi ndi mankhwala ena a insulin, sangathe kuchepetsedwa musanagwiritse ntchito, chifukwa izi zimachepetsa mphamvu yake. Ngati mumasakanikirana ndi zinthu zina zamankhwala am'madzi, mpweya ndiwotheka.

Kuti muchite bwino pochiritsa, Lantus iyenera kugwiritsidwa ntchito mosalekeza, tsiku lililonse pafupifupi nthawi yomweyo.

Ndi mtundu wanji wa insulini yomwe muyenera kugwiritsira ntchito matenda ashuga, endocrinologist angakulangizeni. Nthawi zina, mankhwalawa amagwiritsidwa ntchito mwachisawawa; nthawi zina pamafunika kuphatikiza ma insulin omwe amakhala nthawi yayitali komanso amakhala nthawi yayitali. Chitsanzo cha kuphatikiza kotere ndi kugwiritsidwa ntchito palimodzi kwa Lantus ndi Apidra, kapena kuphatikiza monga Lantus ndi Novorapid.

Muzochitika izi, pazifukwa zina, zimayenera kusintha mankhwalawa Lantus Solostar kupita kwina (mwachitsanzo, kupita ku Tujeo), malamulo ena ayenera kuwonedwa. Chofunika kwambiri, kusinthaku sikuyenera kumayenderana ndi kupsinjika kwakukulu kwa thupi, kotero simungathe kutsitsa mlingo wa mankhwalawa kutengera kuchuluka kwa magawo omwe mungagwiritse ntchito. M'malo mwake, m'masiku oyamba kukonzekera, kuwonjezeka kwa insulini komwe kumathandizira kuti mupewe hyperglycemia. Makina onse amthupi atayamba kugwiritsa ntchito bwino mankhwala, mutha kuchepetsa mankhwalawo kuti akhale olondola. Zosintha zonse munthawi ya mankhwala, makamaka zomwe zimakhudzana ndi mankhwala ndi ma analogues, ziyenera kuvomerezedwa ndi dokotala, yemwe amadziwa momwe mankhwala amasiyana ndi omwe amathandizanso.

Momwe mungasankhire mlingo wa hormone ya basal

Ndizolondola kufunsa wa endocrinologist yemwe angalangize momwe angagwiritsire Lantus insulin; malangizo ogwiritsira ntchito chida ichi sikuti sangayankhe mafunso onse nthawi zonse. Asanayambitse mankhwalawa, wodwalayo ayenera kuwerengetsa mlingo womwe akufuna. Mlingo wa mankhwala omwe kutumikiridwa zimatengera zinthu zingapo: kuchuluka kwa chakudya chamafuta, kulemera kwa thupi, umunthu wa thupi. Pakuwerengera, muyenera glucometer yanu.

Madzi a glue glucose ayenera kukhala m'mabanja onse!

Choyamba, muyenera kuwerengera mlingo wamadzulo. Wodwala ayenera, mwachizolowezi, kudya chakudya chamasana ndipo asamadye zambiri patsikulo, komanso osaba jakisoni wa Lantus Solostar kapena mankhwala ena. Kuyambira pa sikisi koloko, yeretsani magazi anu ola lililonse ndi theka. Ngati kuchuluka kwa shuga m'magazi, ndiye kuti mupeze Mlingo wocheperako wa insulin kuti mulinso matenda a glycemia.

Pofika 22:00 muyenera kuyika muyezo wa insulini kuti mukhale nthawi yayitali. Ngati mugwiritsa ntchito Tujeo Solostar, momwe mankhwala omwe ali ndi 300 PESCES, muyeso woyambira ukhale 6 PISCES. Pambuyo pa maola awiri, kuchuluka kwa glucose kumayesedwanso. Odwala ayenera kujambula mu diary njira zonse zomwe zapezedwa ndikuyimira, komanso mlingo wa insulin, jekeseni ya nthawi ya mayeso ndi kutsata mankhwala. Popewa kukula kwa hypoglycemia, tikulimbikitsidwa kuti nthawi zonse timakhala ndi ma cubes a shuga, msuzi wotsekemera kapena zinthu zina zokhala ndi shuga nanu.

Basulin insulin imakwera usiku, nthawi zambiri pamtunda wa maola 2 mpaka 4. Nthawi yomweyo, muyenera kuyeza shuga wamagazi kamodzi pa ola limodzi. Izi zipangitsa kuti azindikire kuchuluka kwa magawo omwe mankhwalawa amayenera kuperekedwa madzulo kuti azitha kuchepetsa kwambiri shuga, koma osakwaniritsa hypoglycemia usiku.

Njira yomweyo imawerengera kuchuluka kwa insulin glargine Lantus m'mawa. Komabe, ndikofunikira kuyambira ndi tanthauzo la mlingo wamadzulo, kenako kusintha mlingo wa tsiku ndi tsiku.

Kusintha kwa Mlingo

Nthawi zina, muyenera kusintha kuchuluka kwa insulini yoyendetsedwa ndi Solostar. Pali zifukwa zingapo zomwe kufunikira kwamahomoni kumatha kuchuluka kapena kuchepa kwambiri:

Ngati wodwalayo amamwa mowa.
Zinthu zovuta.
Zolakwika mu chakudya, kugwiritsa ntchito zinthu zokhala ndi shuga.
Matenda osiyanasiyana am'mimba, omwe amatha kutsagana ndi matenda am'mimba komanso kusanza.
Kugwiritsa ntchito mankhwala osokoneza bongo.
Kupezeka kwa endocrine pathologies, mwachitsanzo, hypo- kapena hyperthyroidism.
Mimba, makamaka ngati mwana akuyembekezeka kukhala wamkulu.

Pamaso pa somatic pathologies, kusamala kuyenera kulipidwa posintha kuchuluka kwa mahomoni. Nthawi zambiri kufunika kwa mankhwalawa kumawonjezeka, motero odwala ayenera kudya mafuta ena pafupipafupi kuti asawoneke ma hypoglycemia ndi zovuta zina.

Osanyalanyaza moyo wathanzi, kuti mupewe zovuta zathanzi!

Chithandizo cha matenda ashuga chimafuna udindo waukulu kuchokera kwa wodwalayo kuti muchepetse zovuta zonse zomwe zimakhudzana ndi matendawa ndikuchepetsa kuopsa kwa zovuta. Kuphatikiza pa mankhwala osokoneza bongo, zomwe zimapangidwa kuti muchepetse kuchuluka kwa glycemia, ndikofunikira kutsatira moyo wathanzi, kutsatira zakudya. Zithandizanso kuwerenga malangizo omwe mungagwiritse ntchito Lantus Solostar kapena njira zina. Kudziwa malamulo operekera mankhwala, mutha kukwanitsa.

Insulin Yaitali - Zida za Chithandizo cha Matenda A shuga

Ndi matendawa, matenda a shuga amafunikira chithandizo cha insulin. Insulin yochepa ndi insulin yayitali imagwiritsidwa ntchito pochiza matendawa. Moyo wamunthu wodwala matenda ashuga kwambiri umatengera kutsatira malangizo onse azachipatala.

Insulin yowonjezereka yogwira mtima imafunikira pamene kusala kudya kwa shuga m'magazi kumafunikira kusintha. Ma insulin omwe amakhala nthawi yayitali kwambiri ndi Levemir ndi Lantus, omwe wodwalayo amayenera kuperekedwa kamodzi pa maola 12 kapena 24.

Insulin yayitali imakhala ndi katundu wodabwitsa, imatha kutsanzira mahomoni achilengedwe omwe amapangidwa ndi maselo a kapamba. Nthawi yomweyo, amakhala ofatsa pamaselo oterowo, amathandizira kuchira, komwe mtsogolo limalola kukana insulin.

Jekeseni wa insulin wa nthawi yayitali ayenera kuperekedwa kwa odwala omwe ali ndi shuga wambiri masana, koma akuyenera kuwonetsetsa kuti wodwalayo amadya chakudya pasanathe maola 5 asanagone. Komanso, insulin yayitali imapangidwira chizindikiro cha "m'mawa kutacha", maselo a chiwindi akayamba usiku wodwalayo asanadzuke, asokoneze insulin.

Ngati insulin yayifupi imafunikira jekeseni masana kuti muchepetse shuga omwe amaperekedwa ndi chakudya, ndiye kuti insulin yayitali imatsimikizira maziko a insulini, imathandizira kupewa ketoacidosis, imathandizanso kubwezeretsa maselo a pancreatic beta.

Jekeseni wa insulin wa nthawi yayitali amayenera kuthandizidwa kale chifukwa amathandizira wodwalayo kuonetsetsa kuti matenda amtundu wa 2 sangadutse matenda oyamba.

Kuwerengera molondola kwa mlingo wa insulin yayitali usiku

Kuti mukhale ndi moyo wabwinobwino, wodwalayo ayenera kuphunzira momwe angawerengere molondola kuchuluka kwa Lantus, Protafan kapena Levemir usiku, kotero kuti msanga wama glucose amasungidwa pa 4.6 ± 0.6 mmol / l.

Kuti muchite izi, mkati mwa sabata muyenera kuyeza kuchuluka kwa shuga usiku ndi m'mawa pamimba yopanda kanthu. Kenako muyenera kuwerengera mtengo wa shuga m'mamawa mtengo wake wa dzulo usiku ndikuwerengera kuchuluka, izi zikuwonetsa chisonyezo chochepa chofunikira.

Mwachitsanzo, ngati kuchuluka kwochepa kwa shuga ndi 4.0 mmol / l, ndiye kuti gawo limodzi la insulin yayitali ingachepetse chizindikirocho ndi 2.2 mmol / l mwa munthu wolemera makilogalamu 64. Ngati kulemera kwanu ndi makilogalamu 80, ndiye kuti timagwiritsa ntchito njira zotsatirazi: 2.2 mmol / L * 64 kg / 80 kg = 1.76 mmol / L.

Mlingo wa insulin kwa munthu wolemera makilogalamu 80 uyenera kukhala magawo 1.13, chiwerengerochi chimakhala chozungulira kufika kotala ndipo timalandira 1.25E.

Tiyenera kudziwa kuti Lantus sangathe kuchepetsedwa, chifukwa chake imafunikira kubayidwa ndi 1ED kapena 1,5ED, koma Levemir imatha kuchepetsedwa ndikuvulaza ndi mtengo wofunikira. M'masiku otsatirawa, muyenera kuwunika momwe shuga angakhalire kudya ndikuwonjezera kapena kuchepetsa kuchuluka kwake.

Amasankhidwa moyenera komanso molondola ngati, mkati mwa sabata, shuga osala kudya saposa 0.6 mmol / l, ngati mtengo wake umakhala wokwera, ndiye yesani kuwonjezera kuchuluka kwa mankhwala ndi mayunitsi a 0.25 masiku atatu aliwonse.

Glargin ndi mankhwala ena

Kuphatikiza ndi mankhwala ena kumakhudza kagayidwe kachakudya kamene kamayenderana ndi shuga:

Mankhwala ena amalimbikitsa mphamvu ya Lantus. Izi zikuphatikiza ndi sulfonamides, salicylates, mankhwala ochepetsa mphamvu ya glucose, ACE ndi mao inhibitors.
Ma diuretics, sympathomimetics, protease inhibitors, antipsychotic amodzi, mahomoni - akazi, chithokomiro, etc. zimafooketsa zotsatira za insulin glargine.
Zakudya zamafuta a lithiamu, ma beta-blockers kapena kumwa mowa zimayambitsa zovuta - kuwonjezera kapena kufooketsa mphamvu ya mankhwalawa.
Kutenga pentamidine mogwirizana ndi Lantus kumabweretsa spikes m'magulu a shuga, kusintha kwakuthwa kuchokera pakuchepa kupita pakuwonjezeka.

Mwambiri, mankhwalawa amakhala ndi malingaliro abwino. Kodi glulin ya insulin imawononga ndalama zingati? Mtengo wa ndalama m'magawo umachokera ku ruble 2500-4000.

Kuphatikiza pa CHIKWANGWANI pamimba, pali malo ena oyambitsira a Lantus - minofu yachikazi, yachikazi. Kusintha kwake muzochitika izi ndizosafunikira kapena kulibe.

Homoni sangaphatikizidwe pamodzi ndi mankhwala ena a insulin, sangathe kuchepetsedwa musanagwiritse ntchito, chifukwa izi zimachepetsa mphamvu yake. Ngati mumasakanikirana ndi zinthu zina zamankhwala am'madzi, mpweya ndiwotheka.

Kuti muchite bwino pochiritsa, Lantus iyenera kugwiritsidwa ntchito mosalekeza, tsiku lililonse pafupifupi nthawi yomweyo.

M'malo mwake, m'masiku oyamba kukonzekera, kuwonjezeka kwa insulini komwe kumathandizira kuti mupewe hyperglycemia. Makina onse amthupi atayamba kugwiritsa ntchito bwino mankhwala, mutha kuchepetsa mankhwalawo kuti akhale olondola.

Zosintha zonse munthawi ya mankhwala, makamaka zomwe zimakhudzana ndi mankhwala ndi ma analogues, ziyenera kuvomerezedwa ndi dokotala, yemwe amadziwa momwe mankhwala amasiyana ndi omwe amathandizanso.

Kufunika kogwiritsa ntchito magulu ena a mankhwalawa kuyenera kudziwitsidwa kwa adokotala. Mankhwala ena, omwe amagwiritsidwa ntchito ndi Lantus, amalimbikitsa zotsatira zake, pomwe ena, m'malo mwake, amawaletsa, ndikupangitsa kuti pakhale zovuta kulandira chithandizo chokwanira.

Mankhwala omwe amathandizira Lantus:

zoletsa
antimicrobial othandizira
gulu lama salicylates, ma fibrate,
Fluoxetine.

Kukhazikitsa kwawo munthawi yomweyo kungayambitse kudumphadumpha mu shuga komanso kuthamanga kwambiri kwa glycemia. Ngati sizotheka kuletsa ndalama izi, ndikofunikira kusintha mlingo wa insulin.

Kuchepa mphamvu kwa mankhwalawa kumatha kuchitika pakakhudzana ndi mankhwala okodzetsa, gulu la estrogens ndi progestogens, ndi atypical antipsychotic. Mankhwala a Hormonal omwe cholinga chake ndi kuchiritsa matenda a chithokomiro ndi endocrine amatha kufooketsa mphamvu ya hypoglycemic ya Lantus.

Ndikulimbikitsidwa kwambiri kuti musamwe zakumwa zoledzeretsa ndikugwiritsira ntchito mankhwala a gulu la beta-blocker pochiza, zomwe zimachepetsa mphamvu ya mankhwalawa ndikuwonjezera glycemia, kutengera mlingo komanso mawonekedwe a munthu wodwala.

Kuchita mankhwala osokoneza bongo ndi mankhwala angapo kungakhudze kagayidwe ka glucose. Mankhwala otsatirawa amakhudza zochita za Lantus malinga ndi malangizo:

Mankhwala osokoneza bongo omwe amathandizira Lantus (insulin glargine) - zoletsa za ACE, mankhwala osokoneza bongo a hypoglycemic, mao inhibitors, fluoxetine, fibrate, disopyramides, propoxyphene, pentoxifylline, mankhwala a sulfonamide ndi salicylates.
Mankhwala osokoneza bongo omwe amachepetsa mphamvu ya Lantus (insulin glargine) - GCS, diazoxide, danazole, diuretics, gestagens, estrogens, glucagon, isoniazid, somatotropin, phenothiazine zotumphukira, sympathomimetics (epinephrine, terbutaline, salbutaminapaseazeputapulazeputapulatapulatapulataputazigulatapulazigatapulatapulataputaziguligatapodataput hape. mahomoni a chithokomiro
Zonsezi zimathandizira ndikuchepetsa mphamvu ya Lantus (insulin glargine) beta-blockers, mchere wa lithiamu, clonidine, mowa,
Kusakhazikika kwa kuchuluka kwa shuga m'magazi ndikusintha kwa hypoglycemia kupita ku hyperglycemia kungayambitse nthawi yayitali ya Lantus ndi pentamidine,
Zizindikiro za kukakamiza kwa adrenergic zitha kuchepetsedwa kapena kusakhalapo mukamamwa mankhwalawa achifundo - guanfacin, clonidine, reserpine ndi beta-blockers.

Njira yogwiritsira ntchito

Mukamagwiritsa ntchito, tsatirani malamulowo:

Kukhazikitsidwa kwa mankhwalawa kumachitika ndi gawo la mafuta ochepa a ntchafu kapena phewa, matako, khoma lamkati lakumbuyo. Mankhwalawa amagwiritsidwa ntchito kamodzi tsiku lililonse, malo a jakisoni amasintha, ndipo nthawi yofanana imasungidwa pakati pajekeseni.
Mlingo ndi nthawi ya jakisoni zimatsimikiziridwa ndi dokotala - magawo awa ndi amodzi. Mankhwalawa amagwiritsidwa ntchito pawokha kapena kuphatikiza ndimankhwala ena omwe amapangidwa kuti achepetse shuga.
Njira yothetsera jakisoni simasakanizidwa kapena kuchepetsedwa ndi kukonzekera kwa insulin.
Mankhwalawa amagwira ntchito bwino pakhungu, motero sikulimbikitsidwa kuti mupeze jekeseni wamkati.
Wodwala akatembenukira ku insulin glargine, kuwunika mosamala kuchuluka kwa shuga m'magazi ndikofunikira kwa masiku 14-21.

Pakusintha mankhwalawa, katswiri amasankha chiwembucho potengera deta yomwe wodwalayo akuwunika ndikusamala mawonekedwe a thupi lake. Kuzindikira kwa insulin kumawonjezeka pakapita nthawi chifukwa cha njira zoyendetsera kagayidwe kachakudya, ndipo mulingo woyamba wa mankhwalawo umakhala wosiyana.

Kuwongolera kwa regimen ndikofunikanso kuti kusinthasintha kwa kulemera kwa thupi, kusintha kwa magwiridwe antchito, kusintha kwadzidzidzi kwakhalidwe, ndiye kuti, pali zinthu zomwe zingapangitse chidwi chakukula kwa glucose okwanira.

Mwa odwala okalamba, kuwonongeka kwa pang'onopang'ono mu ntchito ya impso kungayambitse kuchepa kwamphamvu kwa zofunikira za insulin.

P / c. Akuluakulu ndi ana opitilira zaka 2.

Lantus® SoloStar ® iyenera kuperekedwa kamodzi pa tsiku nthawi iliyonse, koma tsiku lililonse nthawi imodzi.

Odwala omwe ali ndi mtundu wachiwiri wa matenda a shuga, Lantus® SoloStar ® angagwiritsidwe ntchito ngati monotherapy komanso kuphatikiza mankhwala ena a hypoglycemic.

Zolinga zakukula kwa glucose m'magazi, komanso Mlingo ndi nthawi ya makonzedwe a mankhwala a hypoglycemic ziyenera kutsimikizika ndikusintha payekhapayekha.

Kusintha kwa magazi kungafunikenso, mwachitsanzo, pakusintha kulemera kwa thupi la wodwalayo, moyo wawo, kusintha nthawi ya makonzedwe a insulin, kapena mikhalidwe ina yomwe ingakulitse chiwonetsero chakukula kwa hypo- kapena hyperglycemia (onani "Malangizo apadera"). Kusintha kulikonse kwa insulin kuyenera kuchitika mosamala komanso moyang'aniridwa ndi achipatala.

Lantus® SoloStar® si insulin yosankha yochizira matenda ashuga a ketoacidosis. Pankhaniyi, kukondera kuyenera kuperekedwa / pakubweretsa insulin yochepa.

Mu mankhwalawa othandizira kuphatikiza jakisoni wa basal ndi prandial insulin, 40-60% ya mlingo wa insulin tsiku lililonse wa insulin glargine nthawi zambiri amatumizidwa kuti akwaniritse zosowa za insulin.

Odwala omwe ali ndi matenda a shuga 2, ogwiritsa ntchito mankhwala a hypoglycemic pakamwa, kuphatikiza mankhwalawa kumayamba ndi mankhwala a insulin glargine 10 PESCES kamodzi patsiku, ndipo muyezo wotsatira wa mankhwalawa amasinthidwa payekhapayekha.

Kwa odwala onse omwe ali ndi matenda ashuga, kuyang'anira kuwunika kwa shuga m'magazi kumalimbikitsidwa.

Kusintha kuchokera ku chithandizo ndi mankhwala ena a hypoglycemic kupita ku Lantus® SoloStar ®

Mukasamutsa wodwala ku njira yochiritsira yogwiritsa ntchito nthawi yayitali kapena insulini yodwala pakanthawi kogwiritsa ntchito Lantus® SoloStar ® kukonzekera, kungakhale kofunikira kusintha kuchuluka (kutalika) ndi nthawi ya oyambitsa insulin kapena analogue yochepa masana kapena kusintha Mlingo wamankhwala osokoneza bongo a hypoglycemic .

Mukasamutsa odwala kuchokera jakisoni imodzi ya insulini-isofan patsiku kupita ku gawo limodzi la mankhwala masana, Lantus® SoloStar ®, Mlingo woyamba wa insulin nthawi zambiri sasinthidwa (mwachitsanzo, kuchuluka kwa U / tsiku la Lantus® SoloStar® kumagwiritsidwa ntchito, kofanana ndi kuchuluka kwa IU / tsiku insulin isophane).

Posamutsa odwala kuti ayambe kutumiza insulin-isophan kawiri masana kupita kuntchito imodzi ya Lantus® SoloStar® asanagone kuti achepetse vuto la hypoglycemia usiku ndi m'mawa kwambiri, mankhwalawa a insulin glargine nthawi zambiri amachepetsedwa ndi 20% (poyerekeza ndi mlingo wa tsiku ndi tsiku insulin-isophane), kenako imasinthidwa malinga ndi yankho la wodwalayo.

Lantus® SoloStar® sayenera kusakanikirana ndi insulin ina yokonzekera kapena kuchepetsedwa. Muyenera kuwonetsetsa kuti ma syringe alibe zotsalira zamankhwala ena. Mukasakaniza kapena kuchepetsera, mawonekedwe a insulin glargine amatha kusintha pakapita nthawi.

Mukasintha kuchokera ku insulin ya anthu kupita ku Lantus® SoloStar ® ndipo mkati mwa masabata oyamba pambuyo pake, kuwunikira mosamala metabolic (kuyang'anira kuchuluka kwa shuga m'magazi) moyang'aniridwa ndi achipatala akulimbikitsidwa, ndikuwongolera mtundu wa insulin ngati pakufunika.

Monga ma fanizo ena a insulin yaumunthu, izi ndizofunikira kwambiri kwa odwala omwe, chifukwa cha kupezeka kwa ma antibodies a insulin ya anthu, ayenera kugwiritsa ntchito Mlingo waukulu wa insulin ya anthu.

Odwala awa, akamagwiritsa ntchito insulin glargine, kusintha kwakukulu pamachitidwe a insulin kumawonekera.

Njira yogwiritsira ntchito mankhwala Lantus® SoloStar ®

Mankhwala Lantus® SoloStar ® amathandizira ngati jekeseni wa s / c. Sicholinga cha iv.

Kutalika kwazinthu zambiri za insulin glargine zimawonedwa pokhapokha ngati zimayambitsidwa ndi mafuta osaneneka. Mu / kumayambiriro kwa chizolowezi subcutaneous mlingo zingayambitse kwambiri hypoglycemia.

Lantus® SoloStar ® iyenera kuphatikizidwa ndi mafuta ochulukirapo a m'mimba, mapewa kapena m'chiuno. Masamba a jakisoni amayenera kusinthana ndi jakisoni aliyense watsopano m'malo omwe akutsimikizidwira mankhwala a sc.

Monga momwe zimakhalira ndi mitundu ina ya insulini, kuchuluka kwa mayankho, ndipo chifukwa chake ndi nthawi yake yochitapo kanthu, imatha kusintha motsogozedwa ndi zochitika zolimbitsa thupi komanso kusintha kwina kwa wodwalayo.

Lantus® SoloStar® ndi yankho lomveka bwino, osati kuyimitsidwa. Chifukwa chake, kupumulanso musanagwiritse ntchito sikofunikira.

Ngati Lantus® SoloStar® Syringe pen ikakanika, insulin glargine imatha kuchotsedwa mu cartridge kulowa syringe (yoyenera insulin 100 IU / ml) ndipo jakisoni wofunikira atha kupangidwa.

Malangizo ogwiritsira ntchito ndi kusamalira cholembera chodzaza ndi SoloStar®

Asanayambe kugwiritsa ntchito, cholembera cha syringe chimasungidwa kutentha kwa firiji kwa maola 1-2.

Musanagwiritse ntchito, yang'anani cartridge mkati mwa cholembera. Iyenera kugwiritsidwa ntchito pokhapokha yankho likakhala lowonekera, lopanda utoto, lilibe tinthu tolimba tomwe timayimira, ndikufanana, madzi.

Ma syringe a Emplo SoloStar ® sayenera kugwiritsidwanso ntchito ndipo ayenera kutayidwa.

Popewa matenda, cholembera chodzaza chisanachitike chizingogwiritsidwa ntchito ndi wodwala m'modzi ndipo sayenera kusamutsidwira wina.

Kugwira cholembera SoloStar ® Syringe

Musanagwiritse ntchito SoloStar ® Syringe pen, werengani mosamala zidziwitso zogwiritsira ntchito.

Chidziwitso chofunikira pakugwiritsa ntchito SoloStar® Syringe pen

Musanagwiritse ntchito, gwiritsani ntchito singano yatsopano ndi cholembera chonde ndikuyesani mosamala. Ma singano okhawo omwe amagwirizana ndi SoloStar ® ndi omwe ayenera kugwiritsidwa ntchito.

Malangizo apadera amayenera kuchitika popewa ngozi zokhudzana ndi kugwiritsa ntchito singano komanso mwayi wopatsira matenda.

Palibe chifukwa chomwe muyenera kugwiritsira ntchito cholembera cha SoloStar ® ngati chawonongeka kapena ngati mulibe chitsimikizo kuti chidzagwira ntchito moyenera.

Ndikofunika nthawi zonse kukhala ndi cholembera cha SoloStar ® ngati mungataye kapena kuwononga cholembera cha SoloStar® syringe.

Gawo la Kusungirako Zinthu liyenera kuyang'aniridwa pokhudzana ndi malamulo osungira a SoloStar® Syringe pen.

S / c, pama mafuta ochulukitsa am'mimba, phewa kapena ntchafu, nthawi zonse nthawi imodzi 1 patsiku. Masamba a jakisoni amayenera kusinthana ndi jakisoni aliyense watsopano m'malo omwe akutsimikizidwira mankhwala a sc.

Mu / pakubweretsa njira yanthawi zonse, yolimbikitsidwa ndi sc, kungayambitse kukula kwa hypoglycemia.

Mlingo wa Lantus ndi nthawi yakatsiku lakukhazikitsidwa kwake amasankhidwa payekha. Odwala omwe ali ndi matenda a shuga a 2 mtundu, Lantus angagwiritsidwe ntchito ngati monotherapy komanso kuphatikiza mankhwala ena a hypoglycemic.

Mlingo wa glargine umangosankhidwa ndi dokotala aliyense payekha kwa wodwala aliyense. Jakisoni amapangidwa modumphira m'mafuta m'mimba, m'chiuno, m'mapewa. Jakisoni amaperekedwa jekeseni kamodzi patsiku, munthawi yomweyo. Mukamacheza ndi mankhwala ena omwe wodwala amatenga, kufooka kapena kukulitsa kuchitapo kanthu ndikotheka.

Sinthani mulingo wa glargine ngati:

Zosintha pamagetsi amoyo.
Kulemera kapena kuchepa thupi.
Zakudya Zosintha.
Kuwonetsera kwa opaleshoni.
Kuperewera kwa impso.
Kukula kwa matenda.
Zizindikiro za hypo- kapena hyperthyroidism.

Glargin ali ndi zovuta zingapo:

Kuchulukitsa thukuta.
Ululu m'mutu.
Zosangalatsa pamtima.
Kuyabwa
Kutupa.

Mankhwala osokoneza bongo omwe akupititsa kukoma ayenera kupewedwa.

Mayina amalonda a Glargine ndi Lantus, Lantus SoloStar, Insulin Glargine, Tujeo SoloStar. Mankhwala amagwiritsidwa ntchito pochiza matenda a shuga omwe amadalira odwala a shuga ndi ana opitirira zaka zisanu ndi chimodzi. Glargine ndi analogues amatsutsana chifukwa cha hypersensitivity pazinthu zawo ndi ana osakwana zaka 6. Kusamala kumagwiritsidwa ntchito mukanyamula mwana ndi kuyamwitsa.

Kugwiritsa ntchito glargine kumapangitsa kukwaniritsa kwakukulu kwa hypoglycemic ndi kuchepa kwakukulu kwa mfundo zamatumbo a glycemia ndi glycated hemoglobin. M'malo mwake sangakhale wogwira ntchito.

Kusowa kwa ma contraindication ofunikira, komanso kuthamanga kwambiri, ndi mikhalidwe yokwanira yolimbikitsira glargine kwa anthu odwala matenda ashuga a 2 monga chithandizo chokhacho, komanso kuphatikiza mapiritsi ochepetsa shuga ndi ma insulin apafupi.

Lantus adapangidwa kuti azitha kuthana ndi zovuta zomwe zimakhudzana ndi shuga wambiri komanso wotsika. Iyenera kuperekedwa kokha pakhungu ndipo imaletsedwa - kudzera m'mitsempha.

Kutalika kwa mankhwalawa kumachitika chifukwa chakuti imalowetsedwa m'mafuta oyambira. Tisaiwale kuti kuyambitsidwa kwa mankhwala mwachizolowezi kwamitsempha kungayambitse kukula kwa hypoglycemia.

Chitani izi kamodzi patsiku nthawi yomweyo. Pakuphatikiza jakisoni mankhwala sikuletsedwa. Popewa lipodystrophy, sinthani malo a jakisoni.

Mlingo wa mankhwalawa zimatengera kulemera kwa wodwalayo, momwe amakhalira komanso nthawi ya makonzedwe ake. Amasankhidwa payekha ndi dokotala wopezekapo.

Sikulimbikitsidwa kuti muchepetse kapena kusakaniza insulin Lantus ndi mankhwala ena a insulin. Izi zitha kubweretsa kusintha mu pharmacodynamics ya glargine.

Kusankhidwa kwa Mlingo kumafunika posintha kulemera kwa wodwalayo kapena moyo wake. Komanso kuchuluka kwa mankhwalawa kumatengera nthawi yomwe amayambitsa.

Malinga ndi malangizo, a Lantus (insulin glargine) akuwonetsedwa ngati:

Type Iabetes mellitus (wodalira insulini),
Type II matenda a shuga a mellitus (osadalira insulini) pamagawo okana zotsatira za mankhwala am'mlomo a hypoglycemic, matenda apakati komanso pakati.

Kuti mugwiritse ntchito Lantus malinga ndi malangizo, malamulo awa ayenera kuyang'aniridwa mosamala:

Kubayira mankhwala mu subcutaneous mafuta minofu ya ntchafu, phewa, cham'mimba khoma, matako motsimikiza nthawi imodzi, kamodzi patsiku, kusinthana jakisoni tsiku lililonse,
Mlingo ndi nthawi ya makonzedwe zimasankhidwa payekha ndi madokotala omwe amapita kuchipatala, kupatsidwa mankhwala enaake kapena kumwa mankhwalawa pamodzi ndi mankhwala ena a hypoglycemic amaloledwa,
Lantus jakisoni yothetsera sayenera kuchepetsedwa kapena kusakanikirana ndi insulin ina.
Lantus sayenera kuperekedwa kudzera mu minyewa, ntchito yothandiza kwambiri ya mankhwalawa imawonetsedwa ndi makonzedwe osokoneza bongo,
Mukasinthira ku Lantus kuchokera kukonzekera kwina kwa insulin, ndikofunikira kuyang'anitsitsa kuchuluka kwa shuga m'magulu oyamba a 2-3.

Dongosolo losintha kuchokera ku mankhwala ena a hypoglycemic kupita ku Lantus liyenera kupangidwa ndi adotolo malinga ndi zotsatira za mayeso a udokotala, poganizira zomwe wodwalayo ali nazo. M'tsogolomu, dongosolo la mankhwalawa lingasinthidwe ndikuwonjezereka kwa insulin chifukwa cha kuyendetsa bwino kwa kagayidwe.

Kuwongolera chiwembu kungafunike posintha moyo, chikhalidwe cha anthu, kulemera kwa wodwala, kapena pazinthu zina zomwe zimapangitsa kuti chiwopsezo cha hyper- kapena hypoglycemia chidziwike.

Malinga ndi malangizo ogwiritsira ntchito, insulin Lantus ndi yomwe imapangidwira:

shuga yodalira matenda a shuga (mtundu 1,)
mawonekedwe osadalira insulini (mtundu 2). Amagwiritsidwa ntchito pa nthawi yomwe ali ndi pakati, kulephera kwa mankhwala osokoneza bongo omwe amatsitsa, kupezeka kwa matenda oyamba.

Malangizo ogwiritsira ntchito kuti mankhwalawa akuphwanya:

pamene mphamvu ya thupi pazinthu zothandizira kapena zowonjezera zina za mankhwala ziwonjezereka,
pochiza mwana wosakwana zaka 6.

M'miyezi yoyembekezera, mankhwalawa amatengedwa motsogozedwa ndi katswiri.

- matenda a shuga omwe amafunikira chithandizo cha insulin mwa akulu, achinyamata ndi ana opitilira zaka 6.

Matenda a shuga omwe amafunikira chithandizo cha insulin mwa akulu, achinyamata ndi ana opitilira 2 years.

Hypersensitivity insulin glargine kapena zilizonse zothandiza za mankhwala,

zaka za ana mpaka zaka 2 (kusowa kwa data yazachipatala pakugwiritsa ntchito).

Chenjezo: Amayi oyembekezera (kuthekera kosintha zofunika za insulin panthawi yoyembekezera komanso pambuyo pobala).

Matenda a shuga omwe amafunikira chithandizo cha insulin mwa akulu, achinyamata ndi ana opitilira zaka 6.

Hypersensitivity to insulin glargine kapena aliyense wa opezekapo,

ana ochepera zaka zisanu ndi chimodzi (pakadali pano palibe zambiri zakugwiritsa ntchito).

Chenjezo liyenera kugwiritsidwa ntchito mwa amayi apakati.

Insulin Lantus SoloStar imagwiritsidwa ntchito pa matenda ashuga amitundu iwiri kuposa zaka 6.

Kodi zotsutsana ndi kugwiritsa ntchito mankhwalawa Lantus ndi ziti? Malangizo ogwiritsira ntchito mankhwalawa akuwonetsa magulu awiri a anthu omwe mankhwalawo amakwiriridwa.

Osagwiritsa ntchito mankhwalawa odwala omwe ali ndi vuto la mankhwala kapena pazinthu zina za mankhwalawa. Ichi ndiye chokhacho chotsutsana ndi mankhwalawa.

Sitikulimbikitsidwa kugwiritsa ntchito mankhwalawa kwa ana osakwana zaka 2, popeza palibe umboni wotsimikiziridwa ndi kafukufuku wazachipatala kuti ndi wotetezeka.

Amalembedwa kwa odwala a endocrinologists omwe ali ndi mitundu iwiri yonse ya shuga. Ambiri amakhala achikulire ndi ana opitilira zaka zisanu ndi chimodzi.

Sizingathe kulembedwa kwa anthu omwe ali ndi tsankho pazinthu zazikulu ndi zina zowonjezera.

Lantus aletsedwa kutenga odwala omwe ali ndi dontho la shuga la magazi nthawi zonse.

Zokhudza chithandizo cha ana ndi njirayi, mu mankhwala a ana amatha kugwiritsidwa ntchito pochiza ana omwe ali ndi zaka zopitilira ziwiri.

Ndikofunika kudziwa kuti insulin glargine, yomwe ndi gawo la Lantus, sichinthu chomwe chimathandiza pa matenda a matenda ashuga a ketoacidosis. Mfundo ina yofunika ndi iyi: mankhwalawa ayenera kugwiritsidwa ntchito mosamala kwa anthu omwe ali pachiwopsezo cha matenda a hypoglycemia.

Sizoletsedwa kugwiritsa ntchito insulin glargine kwa anthu omwe sagwirizana ndi chinthu ichi chifukwa cha tsankho. Kugwiritsa ntchito Lantus Solostar molingana ndi malangizo omwe ana omwe ali ndi zaka zosakwana 6 amaletsa sikuti. Ndi mwana wachikulire yekha amene angagwiritse ntchito. Zotsatira zoyipa:

achina,
zosokoneza kagayidwe,
kukhumudwa kwamanjenje,
thupi siligwirizana
kuwonongeka kwamawonekedwe
myalgia.

Pathological zimachitika pakhungu mu mawonekedwe a zotupa ndi kuyabwa amapezeka mwa anthu osaposa zaka 18-20, ndipo wodwala wamkulu kuposa m'badwo uno samakonda kukumana ndi zotere, makamaka chifukwa cha mawonekedwe amunthu.

Hypoglycemia, kuchepa kwakukulu kwa shuga m'magazi, ndizovuta zomwe zimachitika mwa odwala omwe amagwiritsa ntchito insulin. Kumbali ya dongosolo lamkati lamanjenje, kumangokhala wotopa, kukwiya, kusowa chidwi komanso kugona.

Kukomoka komanso kukomoka kusanachitike ndikotheka, kumakhala kupweteka mseru, kupweteka mutu, kusokonezeka chifukwa cha chikumbumtima, kusokonezeka kwa ndende.

Zotsatira za glycemia, wodwalayo amatha kukhala ndi nkhawa nthawi zonse, zomwe zimapangitsa kuti azilephera kudya. Kukuwonekera kumawonekera, khungu lotumbululuka, palpitations, kuchuluka thukuta.

Zotsatira zoyipa kuchokera ku chitetezo chamthupi ndizotupa pakhungu, pamakhala chiopsezo chachikulu chogwedezeka kwa chikhalidwe cha angioneurotic, bronchospasm. Chithunzichi chitha kukhala champhamvu poyerekeza ndi kukhalapo kwa matenda osachiritsika ndikuwopseza moyo wa wodwalayo.

Zowonongeka, monga yankho la insulin, ndizosowa. Pathology imagwirizanitsidwa ndi kusintha kwa minofu yofewa turgor, yomwe ndiyosakhalitsa.

Mwinanso kuphwanya njira yogwetsera maso a maaso. Chosowa kwambiri, koma chotheka cha Lantus ndi myalgia - ululu wammbuyo.

M'dera lazithandizo zamankhwala, kutupira pang'ono, kufupika komanso kuyabwa, kupweteka pang'ono kumayamba. Zofewa minofu edema ndizosowa.

Kugwiritsa ntchito molakwika Lantus, bongo ndi lotheka, lomwe limafotokozedwa mwaukali wa glycemia. Popanda chithandizo chanthawi yake, vutoli limatha kupha. Zizindikiro za bongo ndi kukhudzana, kusokonezeka kwa chapakati mantha dongosolo, kugunda kwambiri glycemia, chikomokere.

Insulin Lantus imakhala ndi mphamvu yayitali, imapangitsa kagayidwe ka glucose ndikuwongolera kagayidwe kazakudya. Mukamamwa mankhwalawa, shuga wambiri ndi minofu ndi minofu yamafuta imathandizidwa. Komanso, wothandizirana ndi mahomoni amathandizira kupanga mapuloteni. Nthawi yomweyo, proteinolysis ndi lipolysis mu adipocytes ndizoletsa.

Insulin Lantus sinafotokozeredwe tsankho kwa zinthu zomwe zingagwire ntchito kapena zinthu zothandiza. Kwa achinyamata, mankhwalawa amalembedwa pokhapokha ali ndi zaka 16.

Kusamalidwa kwapadera kuyenera kuchitika mukamapanga proliferative retinopathy, kuchepetsedwa kwa ziwalo zamkati ndi ziwalo. Kuyang'ana kuchipatala kumafunikanso kwa odwala omwe ali ndi zobisika za hypoglycemia. Matendawa amatha kufinya matendawa ndimatenda amisala, malingaliro osatha a matenda a shuga.

Malinga ndi ziwonetsero zovuta, zimaperekedwa kwa odwala okalamba. Zomwezi zikugwiranso ntchito kwa anthu omwe asintha kuchokera ku insulin yakuchokera kwa nyama kupita kwa munthu.

Malinga ndi malangizo a Lantus adatsutsana:

Ndi chidwi chachikulu ndi insulin glargine kapena chilichonse chothandiza cha mankhwalawo.
Ana osakwana zaka 6.

Amayi oyembekezera ayenera kugwiritsidwa ntchito mosamala, moyang'aniridwa ndi dokotala.

Mitundu ya kumasulidwa ndi mtengo wa mankhwalawo

Zomwe zimagwiritsa ntchito mankhwalawa ndi glargine ya mahomoni. Zothandiza zimaphatikizidwanso: zinc chloride, hydrochloric acid, m-cresol, sodium hydroxide, madzi a jakisoni ndi glycerol. Mankhwalawa amasiyana ndi mitundu yambiri ya insulin momwe amamasulidwa.

OptiKlik - phukusi limodzi lili ndi makatoni 5 a 3 ml iliyonse. Makatoni amapangidwa ndigalasi labwino.
Cholembera cha syringe chimagwiritsidwa ntchito mophweka - ndi kukhudza kwa chala, chopangidwira 3ml.
Lantus SoloStar makatiriji ali ndi 3 ml ya thunthu. Makatoni awa amaikiratu cholembera. Pali zolembera 5 zotere mu phukusi, zokha zimangogulitsidwa popanda singano.

Mankhwalawa ndi mankhwala omwe akhala akuchita kwa nthawi yayitali. Koma kodi Lantus insulin imawononga ndalama zingati?