Insulin Tujeo: malangizo ndi kuwunika

Yothetsera jakisoni 300 IU / ml, 1.5 ml

1 ml yankho lili:

ntchito yogwira - insulin glargine 300 PESCES,

obwera: meta-cresol, zinc chloride, glycerin (85%), sodium hydroxide, hydrochloric acid, madzi a jakisoni

Yankho lomveka bwino, lopanda maonekedwe omwe mulibe zoipitsa zooneka ngati makina.

Mankhwala

Pharmacokinetics

Madzi ndi kugawa

Mwa odzipereka athanzi komanso odwala matenda a shuga, pambuyo pobayira jakisoni wa Tujeo SoloStar ®, kuchuluka kwa insulin m'magazi a seramu kumawonetsa kuyamwa pang'onopang'ono komanso kwa nthawi yayitali poyerekeza ndi insulin glargine 100 IU / ml, zomwe zimatsogolera ku mbiri yapa nthawi yayitali.

Mapulogalamu a Pharmacokinetic amagwirizana ndi zochitika zamankhwala a Tujeo SoloStar ®.

Kuphatikizira kwofananira mkati mwa achire osiyanasiyana kumatheka pambuyo pa masiku 3-4 tsiku ndi tsiku makonzedwe a mankhwala a Tujo SoloStar ®.

Pambuyo popukusira pang'onopang'ono wa Tujeo SoloStar ®, kusinthika kwazomwe zimawonekera pang'onopang'ono kwa insulin kwa maola 24 mu momwe zimakhalira zofananira ndende ya wodwala yemweyo anali ochepa (17.4%).

Pambuyo pa jekeseni wa subcutaneous, insulin glargine imapangidwa mofulumira kuti ipange ma metabolites awiri ogwira ntchito, M1 (21A-Gly-insulin) ndi M2 (21A-Gly-des-30B-Thr-insulin). Mu madzi a m'magazi, gawo lalikulu lozungulira ndi metabolite M1.

Kuwonetsedwa kwa metabolite ya M1 kumawonjezeka ndi kuwonjezeka kwa mlingo wa insulin glargine. Kafukufuku wa pharmacokinetics ndi pharmacodynamics akuwonetsa kuti kuchitira jakisoni wa insulin glargine makamaka chifukwa cha kuwonetsedwa kwa M1. Mwa kuchuluka kwa odwala sikunali kotheka kuti mupeze insulin glargine ndi metabolite M2, ndipo muzochitika zomwe zingatsimikizidwe, kutsimikiza kwawo sikudalira mlingo womwe umaperekedwa ndi mtundu wa insulin glargine.

Pambuyo pakukonzekera kwamitsempha, miyoyo ya insulin glargine ndi insulin yaumunthu idafanana. Hafu ya moyo pambuyo subcutaneous makonzedwe a Tujo SoloStar ® amatsimikiza ndi mulingo wa mayamwidwe subcutaneous zimakhala. Hafu ya moyo wa Tujeo SoloStar ® pambuyo pothandizidwa ndi subcutaneous ndi maola 18-19 ndipo sizimatengera mlingo.

Mankhwala

Ntchito yayikulu ya insulin, kuphatikiza insulin glargine, ndikuwunikira kwa kagayidwe ka shuga. Insulin ndi kufananiza kwake kumachepetsa kuchuluka kwa shuga m'magazi ndikulimbikitsa kuyamwa kwa glucose ndi zotumphukira zimakhala, makamaka minofu yam'mimba ndi minyewa ya adipose, komanso poletsa mapangidwe a shuga mu chiwindi. Insulin imalepheretsa lipolysis mu adipocytes, inhibits proteinolysis ndikuwonjezera kaphatikizidwe ka mapuloteni.

Glulin insulin ndi chithunzi cha insulin ya anthu yopangidwa kuti ikhale ndi mphamvu zochepa pH. Pa pH 4, insulin glargine imatha kusungunuka. Pambuyo jakisoni mu mnofu wotsekemera, acidic solution imatha, yomwe imayambitsa mapangidwe, kuchokera komwe insulin glargine imamasulidwa mosalekeza. Monga taonera m'maphunziro omwe amagwiritsa ntchito njira ya euglycemic clamp yokhudzana ndi odwala omwe ali ndi matenda a shuga 1, mphamvu yotsitsa glucose yotsika mtengo ya mankhwala a Tujo SoloStar ® inali yokhazikika komanso yopitilira kuyerekeza ndi insulin glargine 100 IU / ml pambuyo pokhwimitsa chitetezo. Kuchita kwa mankhwalawa Tujo SoloStar ® kumatha maola opitilira 24 (mpaka maola 36) pa Mlingo woyenera. Mu kafukufuku wazachipatala ndi zamankhwala, kupatsidwa mankhwala a insulin glargine ndipo insulin ya anthu imatsimikizirika kuti ndi yolimba ngati imagwiritsidwa ntchito mu Mlingo womwewo. Monga ndi ma insulin ena, nthawi ya insulin glargine imatha kukhudzidwa ndi zochitika zolimbitsa thupi komanso zina.

Kuchita Mwachipatala ndi Chitetezo

Kuchita kwathunthu ndi chitetezo chonse cha Tujeo SoloStar ® (insulin glargine 300 IU / ml) kamodzi patsiku pakuwongolera glycemic kuyerekezedwa ndi komwe kumapangitsa insulin glargine 100 IU / ml kamodzi patsiku poyera, mayesero osasankhidwa m'magulu ofanana omwe ali ndi magwiridwe antchito omwe amakhala mpaka 26 milungu, kuphatikiza odwala 546 omwe ali ndi matenda amtundu 1 komanso odwala 2474 omwe ali ndi matenda a shuga a 2.

Zotsatira zomwe zimapezeka m'mayesero onse azachipatala ndi Tujeo SoloStar ® zimawonetsa kuti kuchepa kwa glycated hemoglobin HbA1c mtengo poyerekeza ndi mtengo woyambira kumapeto kwa phunziroli siliwotsika poyerekeza ndi kayendetsedwe ka insulin glargine 100 IU / ml. Chiwerengero cha odwala omwe akwaniritsa chandamale HbA1c (pansipa 7%) chinali chofanana m'magulu onse awiriwa.

Kutsika kwa plasma glucose kumapeto kwa maphunzirowa ndi Tujeo SoloStar ® kunali kofanana ndi komwe kumapangitsa insulin glargine 100 IU / ml kutsika pang'ono pang'onopang'ono panthawi yopereka gawo ndikuyambitsa Tujeo SoloStar ®. Glycemic control inali yofanana ndi kayendetsedwe ka Tujeo kamodzi patsiku m'mawa kapena madzulo.

Kusintha kwa HbA1c sikudalira mtundu, mtundu, zaka, kapena kutalika kwa matenda ashuga (

Tujo SoloStar

Mankhwala Tujeo anapangidwa ndi kampani yaku Germany ya Sanofi. Idapangidwa pamaziko a glargine, omwe amasintha kukhala insulin yotalika kwa nthawi yayitali, yomwe imatha kuyendetsa bwino magazi shuga, kupewa kusintha kwadzidzidzi. Tujeo ilibe zotsatirapo zoyipa, pomwe pali malo olimbikitsira ena. Mavuto ndi zotsatira zoyipa pamachitidwe amanjenje ndi mtima zimatha kupewedwa. Tujeo ndi yoyenera pochiza matenda amtundu woyamba 1.

Pharmacodynamics ndi pharmacokinetics

Tujeo ndi chithunzithunzi cha insulin ya anthu, yomwe imapangidwanso ndi kubwereza kwa bacteria bacteria. Chochita chachikulu cha insulin ndikuwongolera momwe thupi limadyera shuga. Amachepetsa kuchuluka kwa glucose, kumawonjezera mayamwidwe mu minofu ya adipose ndi minofu yamatumbo, kumawonjezera kupanga mapuloteni, kumalepheretsa kuphatikizika kwa shuga ndi lipolysis m'maselo a mafuta. Zotsatira za kugwiritsa ntchito mankhwalawa Tujo SoloStar zikuwonetsa kuti pali kuyamwa kotalika, kotenga maola 36.

Poyerekeza ndi glargine 100, mankhwalawa amawonetsa kupindika kocheperako nthawi. Masana pambuyo pobayira jekeseni wa Tujeo, kusiyanasiyana kunali 17,4%, komwe ndi kotsika. Pambuyo pa jekeseni, insulin glargine imakhala ndi metabolism yothamanga panthawi yopanga ma metabolites a M1 ndi M2. Madzi a m'magazi pamenepa amakhala ndi kukhathamiritsa kwakukulu ndi metabolite M1. Kuchulukitsa kwa mankhwalawa kumapangitsa kuti chiwonetsero cha metabolite chiwonjezeke.

Malamulo a insulin

Subcutaneous makonzedwe pamimba, m'chiuno ndi mikono. Tsambalo la jakisoni liyenera kusinthidwa tsiku lililonse kuti lipangidwe mapangidwe a zipsera ndi kuwonongeka kwa minofu yolowerera. Kuyambitsa mtsempha kumayambitsa matenda a hypoglycemia. Mankhwalawa amatha nthawi yayitali ngati jakisoni wapangidwa pansi pa khungu. Mlingo wa insulin umachitika pogwiritsa ntchito cholembera, jakisoni imakhudza pafupifupi magawo 80. Ndikotheka kuwonjezera mlingo pakugwiritsa ntchito cholembera mu 1 unit.

Cholembera adapangira Tujeo, chomwe chimachotsa kufunikira kwa kuchuluka kwa mulingo. Syringe wamba ikhoza kuwononga cartridge ndi mankhwalawo ndipo sangakulole kuyeza molondola mlingo wa insulin. Singano ndiyotaya ndipo ndiyenera kuyilowetsa ndi jakisoni aliyense. Syringe imagwira ntchito molondola ngati dontho la insulin likuwoneka pamsonga pa singano. Popeza kuperewera kwa singano ya insulini, pamakhala ngozi yoti angatsekedwe panthawi yogwiritsa ntchito kwachiwiri, komwe sikungalole kuti wodwalayo alandire insulini yeniyeni. Cholembera chingagwiritsidwe ntchito kwa mwezi umodzi.

Malangizo apadera

Odwala omwe ali ndi matenda ashuga ayenera kuyang'anitsitsa kuchuluka kwa shuga, azitha kupangira jakisoni moyenera, ndikuletsa hypoglycemia ndi hyperglycemia. Wodwala ayenera kukhala osamala nthawi zonse, kudzisamalira pakumwa mankhwala a insulin chifukwa cha izi. Odwala omwe ali ndi vuto la impso ayenera kudziwa kuti kufunika kwa mahomoni nthawi zina kumachepetsedwa chifukwa chakuchepa kwa insulin metabolism komanso kuchepa kwa mphamvu ya gluconeogeneis.

Zochita Zamankhwala

Mankhwala ena angakhudze kagayidwe ka glucose. Ngati atengedwa limodzi ndi mahomoniwo, ndiye kuti zingakhale zofunikira kumveketsa bwino. Mwa zina mwa mankhwala omwe angapangitse kuchuluka kwa hypoglycemic kwa insulin ndikuthandizira kuyambika kwa hypoglycemia ndi Fluoxetine, Pentoxifylline, sulfonamide antibacterial, fibrate, ACE inhibitors, MAO inhibitors, Disopyramide, Propoxyphene, salicylates. Ngati mutenga ndalamazi nthawi yomweyo ngati glargine, mudzafunika musinthe.

Mankhwala ena amatha kupangitsa kuti mphamvu ya hypoglycemic ikhale yofooka. Zina mwa izo ndi Isoniazid, glucocorticosteroids, kukula kwa ma protein, proteinase inhibitors, mankhwala omwe ali ndi phenothiazine, Glucagon, sympathomimetics (Salbutamol, Terbutaline, Adrenaline), estrogens ndi progestogens, kuphatikiza zomwe zimapezeka mu njira yoletsa kulera kwa mahomoni, mahomoni a chithokomiro, ma gwero a atyroidane. antipsychotic (clozapine, olanzapine), diazoxide.

Mukagwiritsidwa ntchito limodzi ndikukonzekera ndi ethanol, clonidine, mchere wa lithiamu kapena beta-blockers, mphamvu ya mahomoni amatha kuchepa mphamvu. Kugwiritsa ntchito pamodzi ndi Pentamidine kumatha kubweretsa hypoglycemia, nthawi zambiri kusintha kwa hyperglycemia. Kugwiritsa ntchito pioglitazone limodzi ndi mahomoni nthawi zina kungapangitse kuwonekera kwa kulephera kwa mtima.

Contraindication ndi zoyipa

Mankhwala sayenera kugwiritsidwa ntchito ngati pali tsankho la munthu pazigawo zake. Tujeo ndi yoyenera okha akuluakulu. Chenjezo liyenera kugwiritsidwa ntchito mwa amayi apakati, anthu omwe ali ndi vuto la endocrine komanso zaka zapenshoni. Tujeo sioyenera matenda ashuga a ketoacidosis. Zotsatira zoyipazi zimapezeka:

• thupi lawo siligwirizana
• lipodystrophy,
• kunenepa
• kuwonongeka kwamawonekedwe
• myalgia
• hypoglycemia.

Migwirizano yogulitsa ndikusunga

Mankhwala amaperekedwa mu mankhwala okhala ndi mankhwala. Ndikofunika kusungidwa pamalo otetezedwa ndi kuwala, kutentha kuyenera kukhala pakati pa 2-8 ° C. Bisani ana. Mukasunga mankhwalawa, ndikofunikira kuonetsetsa kuti zolembera sizikugwirizana ndi chipinda chaulere, chifukwa insulin singathe kuzizira. Mukatha kugwiritsa ntchito koyamba, sungani mankhwalawa kwa milungu yopitilira 4.

Ma Analogs a Insulin Tujeo

Ubwino wa mankhwalawa pamwamba pa analogues ndizodziwikiratu. Kuchitapo kwanthawi yayitali chonchi (mkati mwa maola 24-35), komanso kumwa kwambiri, komanso kuwongolera molondola kuchuluka kwa shuga m'magazi (ngakhale kuti pali majekeseni ochepa), ndipo nthawi ya jakisoni singayang'anitsidwe bwino. Mwa zina zomwe zimafanana ndi insulin ya m'badwo watsopano:

Mtengo wa Insulin Tujeo

Ku Russia, Tujeo ikhoza kupezeka kwaulere, imagulitsidwa mokhazikika malinga ndi malangizo a dokotala. Mutha kugula ku malo ogulitsira kapena pa intaneti kwa odwala matenda ashuga. Mtengo wapakati ndi ma ruble 3100, ochepera ndi 2800 rubles.

Maria, wazaka 30 Ndinkakonda insulin yatsopano, ndakhala ndikugwiritsa ntchito mankhwala kwa chaka chopitilira chaka. Poyamba panali Tresiba. Chachikulu ndichakuti palibe chiopsezo cha hypoglycemia, pambuyo pa insulini yapita panali zotsatira zosasangalatsa. Ndayiwala za kudumpha mu shuga, Tujeo samasinthasintha. Sindikawona kufunikira kwa zokhwasula-khwasula. Zilonda zimachitika mosavuta, simudzakhala olakwika ndi mlingo.

Victor, wazaka 43. Ndinafunika kukonza hypoglycemia nditatha kugwiritsa ntchito mankhwala a tresib. The endocrinologist adalangiza lantus tujeo. Kwa miyezi isanu ndi umodzi tsopano sindikudziwa mavuto aliwonse, ngakhale oonda. Ndimakonda kuti simukufunika kuchita jakisoni wambiri, mankhwalawa amagwira ntchito mthupi kwanthawi yayitali. Ndikofunika kuti cholembera chovomerezeka chomwe chimayenerera molondola.

Rosie, Tujeo wazaka 24 akhala akugwiritsa ntchito kwa sabata limodzi. Zinali zowopsa kuwoloka. Ndadwala matenda ashuga amtundu woyamba kwa nthawi yayitali, ndipo panalibe kufuna kuyesa. M'mbuyomu Lantus. Pokhudzana ndi kusinthaku, sindinazindikire zomwe zasintha, koma ndi Tujeo kudumphadumpha usiku kumayima, ndikufuna kudya zochepa. Ndikupangira Tujeo ngati insulin yapamwamba kwambiri komanso yamakono.

Zotsatira za pharmacological

Kutanthauza othandizira a hypoglycemic. Chifukwa cha ntchito ya insulin, kagayidwe kachakudya ka glucose kamayendetsedwa. Kuphatikizika kwa shuga m'magazi kumachepetsedwa chifukwa cha kuyamwa bwino kwa minofu ndi mafupa amtundu wa adipose. Potere, mapangidwe a polysaccharide complexes mu chiwindi amalephereka, ndipo kapangidwe kazinthu zopanga mapuloteni zimachulukana.

Mankhwalawa amapezeka mu mawonekedwe a yankho lomveka bwino la jakisoni mu 1.5 ml.

Pharmacokinetics

Poyerekeza ndi insulin yochepa, pambuyo pobayira jekeseni wa mankhwalawa, chinthu chogwira chimaphatikizidwa kuchokera kuzinthu zowonongeka pang'onopang'ono. The kwambiri ndende ya yogwira mankhwala m'magazi amawonedwa 2 mawola jekeseni. Zimapangidwa makamaka m'chiwindi. Amachotseredwa mu mawonekedwe a metabolites ofunikira. Hafu ya moyo ili pafupifupi maola 19.

Zizindikiro zogwiritsidwa ntchito

Kugwiritsa ntchito mankhwalawa kumalimbikitsidwa pochiza mitundu yonse ya matenda ashuga mwa akulu.

Kugwiritsa ntchito mankhwalawa kumalimbikitsidwa pochiza mitundu yonse ya matenda ashuga mwa akulu.

Kutenga Tujeo?

Ndikofunika kuti mupeze jakisoni nthawi imodzi 1 patsiku. Ngati jakisoni imodzi ikufunika, ndiye kuti jakisoni ingachitike nthawi ina iliyonse masana. Ngati sikutheka kuyikamo jakisoni nthawi yomweyo, ndikulimbikitsidwa kuchita njirayi pasanathe maola atatu nthawi isanayambe kapena itatha. Zochita za mankhwala ziyenera kukhala zokwanira tsiku lonse.

Momwe mungawerengere mlingo?

Pochiza matenda amtundu wa 1 shuga, jakisoni amalimbikitsidwa ndi zakudya. Tiyenera kukumbukira kuti mlingo umasankhidwa kwa wodwala aliyense payekhapayekha, koma osayenera kupitirira mayunitsi zana patsiku. Kuti muchite bwino, mankhwalawa amaphatikizidwa ndi ma insulin ena osakhalitsa.

Ndikofunika kuti mupeze jakisoni nthawi imodzi 1 patsiku. Ngati jakisoni imodzi ikufunika, ndiye kuti jakisoni ingachitike nthawi ina iliyonse masana.

Zochizira matenda amtundu wa 2 shuga, tsiku lililonse mlingo umafika mpaka 200 mayunitsi. Ngati wodwala sakwanira, akhoza kuphatikizidwa ndi othandizira ena omwe ali ndi vuto la hypoglycemic.

Momwe mungagwiritsire ntchito cholembera?

Simungathe kulowa mankhwalawa kudzera m'mitsempha. Izi zimatha kubweretsa insulin kuipitsidwa ndi mankhwala ena ndikupangitsa hypoglycemia yayikulu. Jakisoni amachitika m'mafuta ochepa okha.

Khola la syringe limadzazidwa kale ndi yankho ndipo 1 mpaka 80 magawo a mankhwalawa amaperekedwa. Pankhaniyi, kukweza sikuyenera kupitirira 1 unit. Cholembera cha syringe chodzazidwa chidapangidwira kukhazikitsidwa kwa Toujeo SoloStar, kotero palibe kuwerengera kowonjezera kwa mlingo kumachitika.

Mankhwala sayenera kuthiridwa kuchokera mu cholembera china kupita ku chinthu china cha insulin. Izi zimatha kuyambitsa bongo. Zingano za jekeseni iliyonse zimayikidwa zatsopano. Ayenera kukhala osabala.

Musanayambe kugwiritsa ntchito cholembera, muyenera kuphunzira mosamala malangizo ogwiritsa ntchito, omwe ayenera kuphatikizidwa ndi kuyambitsa koyambirira. Kutetezedwa kwakukulu panthawi ya jakisoni sikuyenera kungosintha singano nthawi iliyonse. Onetsetsani kuti syringe imagwiritsidwa ntchito ndi munthu m'modzi yekha.

Pa gawo la kagayidwe ndi zakudya

Kuwonjezeka kwakuthwa kwa chakudya kumachitika, wodwalayo amakhala ndi njala nthawi zonse. Vutoli limatha kubweretsa kunenepa kwambiri. Chifukwa cha kukulitsa kwa hypoglycemia, kagayidwe kake kamakulirakulira, komwe kumayambitsa kuchepa kwa shuga m'magazi chifukwa cha kuperewera kwa glucose metabolism. Carbohydrate ndi metabolism yamafuta amathanso kusokonezedwa.

Zotsatira zoyipa zamankhwala zimatha kukhala matenda osokoneza bongo.
Zotsatira zoyipa za mankhwalawa zimatha kunenepa kwambiri.
Zotsatira zoyipa za mankhwalawa zitha kukhala myalgia.
Zotsatira zoyipa za mankhwalawa zimatha kukhala kuchuluka kwa chilakolako chofuna kudya.

Pa khungu

Zomwe zimachitika mdera lanu zimachitika m'malo opaka jakisoni. Ululu, makulidwe, khungu rede ndikuwotchera zimadziwika.

Nthawi zambiri, pogwiritsa ntchito insulin yomwe imakhalapo nthawi yayitali, thupi limakumana ndi zotsutsana. Amawonetsedwa ndi totupa yapakhungu, kuyimitsa ndi kuyaka. Edema ya Urticaria ndi Quincke ikhoza kukulira.

Zotsatira zoyipa za mankhwalawa zimatha kukhala zotupa pakhungu komanso kuyabwa.
Zotsatira zoyipa za mankhwalawa zimatha kukhala zosawona bwino.
Zotsatira zoyipa za mankhwalawa zimatha kukhala edema ya Quincke.
Zotsatira zoyipa za mankhwalawa zimatha kupanga chidindo patsamba la jakisoni.

Gwiritsani ntchito pa nthawi yoyembekezera komanso mkaka wa m`mawere

Ndi chololedwa kugwiritsa ntchito munthawi ya mayeso. Mu maphunziro, panalibe zoyipa zilizonse zomwe zimagwiritsidwa ntchito ndi mankhwala pa mwana wosabadwayo. Kufunika kwa insulini kumachepa kumayambiriro kwenikweni kwa kubereka, ndipo pamapeto pake, kuwonjezera, kumawonjezeka. Chifukwa chake, pofuna kupewa chitukuko cha hyperglycemia, ndikofunikira kuyang'anira kuchuluka kwa shuga m'magazi a mayi wapakati.

Pambuyo pobereka komanso panthawi yoyamwitsa, kufunika kwa insulin kumachepetsedwa, motero, kusintha kwa mankhwalawa kumafunikira.
Pakulephera kwa impso, insulin metabolism imachepetsa, motero kufunikira kwa thupi kumachepa.
Simungathe kuphatikiza mankhwalawa ndi zakumwa zoledzeretsa.
Saloledwa kuchitira ana mankhwala ngati amenewo.
Ndi chololedwa kugwiritsa ntchito mankhwalawa panthawi yapakati.

Pambuyo pobereka komanso panthawi yoyamwitsa, kufunika kwa insulin kumachepetsedwa, motero, kusintha kwa mankhwalawa kumafunikira.

Gwiritsani ntchito mu ukalamba

Kwa odwala azaka zopitilira 65, njira zoyambirira ndi kukonza ziyenera kukhala zopanda ntchito. Chiwopsezo chokhala ndi hypententcogia yacentic chikuwonjezeka. Kuphatikiza apo, zovuta zina za hypoglycemic zokhudzana ndi kudya kosalekeza kwamtundu wa insulin zimayamba. Chifukwa chake, kusintha kwa mankhwalawa kuyenera kuchitidwa kwa wodwala aliyense payekhapayekha.

Bongo

Mitundu yambiri ya hypoglycemia imakula msanga. Panthawi yakachepa kwambiri, vutoli limatha kusintha potenga chakudya chokwanira. Mivuto yayikulu ikayamba, chikomokere ndi vuto linalake la mitsempha, kuukiraku kumayimitsidwa ndikumayambitsa yankho la dextrose kapena glucagon.

Ndi mankhwala osokoneza bongo osokoneza bongo, kuopseza kotsimikizika ndikotheka.
Ndi mankhwala osokoneza bongo ambiri, chikomokere chingachitike.
Ndi mankhwala osokoneza bongo a mankhwala, kuyambika kwa hypoglycemia ndikotheka.
Ndi mankhwala osokoneza bongo ambiri, zovuta zamitsempha zimatha.

Kuchita ndi mankhwala ena

Mukamagwiritsa ntchito mankhwala ena, mungafunike kusintha mtundu wa insulin, chifukwa kuchuluka kwa shuga m'magazi kumatha kutsika kwambiri, zomwe zimayambitsa kukula kwa hypoglycemia.

Othandizira a Hypoglycemic, salicylates, ACE inhibitors, maantibayotiki ndi ena sulfonamides amachepetsa mphamvu ya insulin. Kukonzekera kwa Beta-lithiamu ndi kukonzekera kwa lithiamu kumachepetsa ndikuwonjezera kuchiritsa kwa kutenga insulin.

Ma diuretics, salbutamol, adrenaline, glucagon, mahomoni a chithokomiro, estrogens, mahomoni ena oletsa kubereka, isoniazid, antipsychotic ndi ma prosthetic inhibitors pomwe amamwa mankhwalawa amachepetsa mphamvu yake ya hypoglycemic.

Othandizira omwewo omwe ali ndi mawonekedwe ofanana ndi achire:

Malangizo a Tujeo SoloStar Zomwe muyenera kudziwa zokhudza insulin Lantus Pangani jakisoni wa insulin bwino! Gawo 1

Wopanga Tujeo

Kampani yopanga: Sanofi Aventis Deutschland GmbH, Germany.

Kuteteza kokwanira ku dzuwa. Osazizira, koma sungani mufiriji kutentha kwambiri osapitirira + 8 ° C.

Ndemanga za Tujeo

Ndemanga zambiri za madotolo ndi odwala ndi zabwino.

Mikhailov AS, wa endocrinologist, ku Moscow: "Anthu ambiri tsopano akudandaula za kusintha kwa mankhwalawa. Insulin yokha ndiyabwino, koma ndikofunikira kwambiri kuwerengetsa mlingo. Pankhaniyi, idzaperekedwa bwino popanda mawonekedwe a mbali."

Samoilova VV, endocrinologist, Nizhny Novgorod: "Apongozi anga akhala akudwala matenda ashuga kwazaka zambiri. Ine, monga dokotala, tidachichotsa ku Lantus, chomwe sitikulandiranso, Toujeo. Zizindikiro zake zandithandizanso. chifukwa ndaphunzira ndekha zotsatira za insulin iyi. Shuga sangathe "kukula" ngati mulingo wake utalekeka.

Anthu odwala matenda ashuga

Karina, wazaka 27, ku Kiev: "Ndimakonda kwambiri insulini yonse, chifukwa imagwiritsidwa ntchito kwambiri, ndipo mumangofunika kupaka jakisoni kamodzi patsiku. Ndi yabwino, yothandiza ndipo siyimasokoneza zochitika za tsiku ndi tsiku. Suzi zimasungidwa nthawi zonse, palibe dumphani, fufuzani pafupipafupi. "

Victor, wazaka 36, ​​Voronezh: "Ndakhala ndikumwa insuliniyi kwa mwezi umodzi. Izi zisanachitike, panali mankhwala ena omwe sanagwiritse ntchito bwino. Ndinaiwalanso zazakumwa ndi izi."

Andrei wazaka 44, ku Moscow: "Poyamba ndimakonda kugwiritsa ntchito Lantus. Tsopano samulemba. Ndikuyenera kubaya Toujeo, yemwe sindimakondwera naye. Ku Lantus, shuga osala kudya anali mpaka 10, tsopano 20-25."