Glycyrrhizic acid

Fomula C42H62O16, dzina la mankhwala: 20-beta-Carboxy-11-oxo-30-norolean-12-en-3-beta-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid.
Gulu lamagulu: antimicrobial, antiparasitic and anthelmintic agents / antiviral agents / antiviral agents (kupatula HIV).
Machitidwe sapha mavairasi.

Mankhwala

Glycyrrhizic acid imagwira ntchito motsutsana ndi ma virus a RNA ndi DNA, kuphatikiza mitundu ingapo ya Varicella zoster, ma virus a Herpes simplex, cytomegaloviruses, ma virus a papilloma aanthu. Mphamvu yotsatsira yomwe mwina imayenderana ndi kuphatikizika kwa syntferon synthesis. M'maselo omwe ali ndi kachilomboka, glycyrrhizic acid imalepheretsa phosphorylation ya mapuloteni omwe amapanga ma virus poletsa phosphokinase. M'magawo oyambira, kubwereza kwama virus kumadodometsedwa, ndikupangitsa kuti virion itulutsidwe ndi capid. Glycyrrhizic acid imalowetsa ma virus kunja kwa maselo, pomwe ma virus a herpes simplex ndi herpes zosasintha. Zimaphwanya kuthekera kwa kachilomboka kupanga zigawo zatsopano zopangira ndi kulepheretsa kulowetsa ma cell tinthu tomwe timalowa mu cell. Glycyrrhizic acid amaletsa ma virus m'magulu omwe si oopsa kwa maselo osagwira ntchito. Kuyamwa kwadongosolo kumayamba pang'onopang'ono. Mukagwiritsidwa ntchito kwanuko, glycyrrhizic acid imakhala yotentha kwambiri kwa maselo omwe ali ndi kachilomboka ndikudziunjikira mu lesion foci. Ma virus omwe amalimbana ndi iodouridine ndi acyclovir amakhudzidwa kwambiri ndi glycyrrhizic acid. Glycyrrhizic acid alinso ndi anti-yotupa, analgesic kwenikweni, amasinthanso kusinthika kwa minofu poyambirira kuwonekera kwa matenda oyambitsidwa ndi tizilombo, komanso mitundu ya zilonda.

Chithandizo cha matenda amtundu woyambitsidwa ndi Herpes simplex mtundu 2 virus (pachimake oyamba, obwerezabwereza), chithandizo cha matenda a mucous nembanemba omwe amayamba chifukwa cha papillomavirus ya anthu, chithandizo cha matenda amkati oyambitsidwa ndi kachilombo ka Varicella zoster (monga gawo la chithandizo chokwanira) colpitis, vaginitis, kupewa matenda opatsirana omwe amapatsirana pogonana.

Mlingo ndi makonzedwe a glycyrrhizic acid

Kirimu: pakani 3-5 pa tsiku kwa omwe akukhudzidwa. Pukuta: kumaliseche - katatu pa tsiku kwa masiku 7-10 (kugwiritsanso ntchito pakatha masiku 10), kunja - kuchokera patali kwa 4-5 masentimita, kutsanulira 6 pa tsiku kwa masekondi 5 (mwina mpaka masiku 10).
Chithandizo cha mankhwalawa chimayima ngati zizindikiro zakukwiyitsa zikuwonekera. Ngati kununkhira kosasangalatsa kapena kukondoweza kumachitika, pitani kuchipatala. Pochiza matenda amtundu wa khungu oyambitsidwa ndi kachilombo ka Varicella zoster, kugwiritsa ntchito glycyrrhizic acid kuyenera kuphatikizidwa ndi pakamwa pofotokoza mwachindunji maanttivitala ena.

Mayina amalonda a yogwira glycyrrhizic acid

Mankhwala osakanikirana:
Glycyrrhizic acid + Phospholipids: Phosphogliv®, Phosphogliv® forte,
Ambroxol + Sodium glycyrrhizinate + Zomera zazitsamba zozungulira: Codelac® Broncho ndi thyme,
Ambroxol + Sodium glycyrrhizinate + Sodium bicarbonate + Thermopsis youma Tingafinye: Codelac® Broncho.

Mphamvu zamankhwala

Glycyrrhizic acid imapezeka pamtundu waukulu wa licorice. Amagwiritsidwa ntchito ngati zotsekemera m'makampani azakudya ndi mankhwala (anti-kutupa, expectorant, antiulcer, lowers testosteronemwa amuna, amachepetsa kuthamanga kwa magazi) Acid nthawi zambiri imawonjezeredwa kumiyeso yamafuta.

Pharmacodynamics ndi pharmacokinetics

Thupi limatha kulepheretsa ntchito yopanga. phosphokinasesKuyimitsa njira phosphorylationmapuloteni m'maselo omwe ali ndi kachilombo. Chida chokwanira komanso chosagwedezeka kachilombo ka herpes zoster ndi nsunguakakhala kunja kwa maselo. Pali kufalikira kwa kukhazikitsidwa kwa tinthu tomwe tili ndi ma virus m'maselo athanzi, wothandizirayo ataya kuthekera kwathunthu pakupanga magawo atsopano.

Ikagwiritsidwa ntchito mopitirira muyeso, pawiri imatha kudziunjikira mu maselo omwe akhudzidwa, pomwe sikugwira mayeso aumisili.

Zizindikiro zogwiritsidwa ntchito

Mankhwala amathandizidwa kuti agwiritsidwe ntchito kwina:

• matenda a pakhungu, kumaliseche, mucosa wamkamwa ndi mphuno kachilombo ka herpes (Mtundu wa 2)
• zochiziratinea versicolormonga gawo la zovuta mankhwala
• ngati prophylactic motsutsana ndi matenda opatsirana ndi ma virus omwe amagonana.

Zotsatira zoyipa

Chifukwa cha kutsika kochepa kwambiri kwa mayamwidwe a glycyrrhizic acid, kusintha kovuta sikosowa.

Zitha kuwonekera ziwengo pa mankhwalawa, omwe akuwoneka ndi kuyabwa komanso kusapeza bwino pa malo ogwiritsira ntchito, sikukuchitika pakhungu lina siligwirizana.

Glycyrrhizic acid, malangizo ntchito (njira ndi Mlingo)

Mlingo wothandizila umatsimikiziridwa payekhapayekha.

Spray imagwiritsidwa ntchito panja. Mankhwalawa amapakidwa kwakanthawi (masekondi angapo) pamtunda womwe wakhudzidwa ndi mtunda wa masentimita 5. Kugwiritsa ntchito kambiri - mpaka katatu pa tsiku.

Kutalika kwa chithandizo kuchokera masiku 5 mpaka 10.

Makamaka, mankhwalawa amayikidwa katatu patsiku, kwa sabata limodzi - masiku 10. Pambuyo masiku 10, tikulimbikitsidwa kubwereza maphunzirowo.

Kirimu amamuthira m'malo omwe akhudzidwa katatu patsiku kwa sabata kapena masiku 10.

Zokonzekera zomwe zili ndi (Analogs)

Dzina Lamalonda Glycyrrhizic Acid: Trisodium mchere wa glycyrrhizic acid, Epigen Intim, Glycyrrhizin.

Kuphatikiza kwa glycyrrhizic acid + Phospholipids akukonzekera: Hepabos, Phosphogliv, Phosphogliv Forte.

Kugwiritsa ntchito mankhwala

Wothandizira kuti musagwiritsidwe ntchito kwina ndi kwanuko. Glycyrrhizic acid imagwira ntchito motsutsana ndi ma virus ndi ma DNA omwe ali ndi RNA, kuphatikiza mitundu ingapo ya Herpes simplex, ma virus a Varicella zoster, ma virus a papilloma a anthu, cytomegaloviruses. Mphamvu yotsatsira ikuwoneka kuti imalumikizidwa ndi kuphatikizidwa kwa mapangidwe a interferon. Imayambitsa kubwereza kwa ma virus m'mayambiliro oyambilira, kumapangitsa kuti vutoli lituluke m'mutu, motero limaletsa kulowa kwake m'maselo. Izi zikuchitika chifukwa cha kusankha kosalekeza kamene kamayambitsa phosphorylating kinase P. Amalumikizana ndi kapangidwe ka kachilomboka, kamasintha magawo osiyanasiyana a ma virus, omwe amatsatiridwa ndi kusapangika kwina kwamatenda a ma virus (omwe ali mwaulere kunja kwa maselo), kutsekereza kukhazikitsidwa kwa tinthu tomwe tili ndi ma cell mu cell ya cell, komanso kufooka ma virus ku kapangidwe kazinthu zopanga zatsopano.

Imaletsa ma virus m'magawo omwe si oopsa kwa maselo omwe amagwira ntchito nthawi zonse.

Ma virus omwe amalimbana ndi acyclovir ndi iodouridine amakhudzidwa kwambiri ndi glycyrrhizic acid.

Ilinso ndi zotsutsa-zotupa, ma analgesic komanso kusintha kwamphamvu kwa minyewa posonyeza kuwoneka koyambitsa matenda a virus komanso mitundu ya zilonda.

Zimatha kugwiritsidwa ntchito ndi mankhwala a glucocorticosteroid pamene atengedwa limodzi. Katunduyu amagwiritsidwa ntchito pang'onopang'ono kuchepetsa nthawi yamankhwala omwe amapezeka ndi matenda a m'matumbo a bronchial asthma, ndi chithandizo chakunja ndi kalasi 1-4 corticosteroids.

Sinthani mankhwala osokoneza bongo |Njira zabwino za asidi

Thupi glycyrrhizin limakhala mu muzu wa licorice, limakhala lokoma kwambiri kuposa shuga loyera wamba, momwe limagwirira ntchito limafanana ndi zochita za mahomoni a adrenal cortex ndi cortisol. Chifukwa cha izi, asidi ali ndi antimicrobial, anti-allergenic komanso anti-kutupa.

Glycyrrhizic acid amathandiza kulimbana ndi matenda a chithokomiro, komanso ma pathologies omwe amagwirizana ndi matenda a shuga, mwachitsanzo, matenda oopsa komanso obwera.

Acid imakhala ndi phindu pa mucous nembanemba; mu shuga, imathandizira kupanga insulin. Mankhwala sangathe kusintha shuga mokwanira, chifukwa pali zotsutsana zomwe zimagwiritsidwa ntchito nthawi yayitali komanso zochuluka.

Katunduyu amatengedwa ngati mankhwala abwino; kwa odwala matenda a shuga amadziwika kuti ndi njira yochitira:

1. kukonza magwiridwe antchito,
2. kusangalala
3. kuthetsa kutopa.

Kuphatikiza apo, tikulimbikitsidwa kuti mugwiritse ntchito ngati gawo la zakumwa za tonic, ngati mbali ya zonunkhira. Acid nthawi zambiri imawonjezeredwa pazinthu zamafuta.

Kodi kuchepa kwa chinthucho ndi chiyani?

Mankhwala ozikidwa pa glycyrrhizic acid amawonetsedwa kwa anthu odwala matenda ashuga pamaso pa matenda: herpes zoster, human papillomavirus, matenda oyamba ndi obwereza, nonspecific colpitis, vaginosis. Komanso, mankhwalawa amatha kulepheretsa kutenga kachilombo ka herpes.

Kugwiritsa ntchito asidi osagwiritsidwa ntchito mosaloledwa ndi oletsedwa, makamaka panthawi yapakati nthawi iliyonse, chidwi chambiri cha zinthu zomwe zimagwira, panthawi yoyamwitsa.

Mlingo wa mankhwala nthawi zonse zimatengera zomwe zikuwonetsa, mtundu wa glycyrrhizic acid. Wodwala matenda ashuga akafuna kuchotsa zotupa za pakhungu la herpetic, kukonza kirimu kumalimbikitsidwa, umayikiridwa ndi wosanjikiza woloza kumalo omwe akhudzidwa, ndipo madera athanzi ayenera kugwidwa:

• pafupipafupi ntchito - mpaka 6 pa tsiku,
• chithandizo chikuchitika mpaka kuchira kwathunthu,
• Kuphatikiza pamodzi ndikotheka.

Ndi anthu papillomavirus, anthu odwala matenda ashuga amaikidwa glycyrrhizic acid kuphatikiza ndi mankhwala ena, kuwonjezera apo amagwiritsa ntchito ndalama kuwonongedwa kwa thupi kapena mankhwala. Pafupipafupi kugwiritsidwa ntchito kumakhala kokwanira nthawi 6 pa tsiku.

Ndi matenda a shuga 1 amtundu wotchedwa mellitus ndi nonspecific colpitis, mankhwalawa amachokera masiku 7 mpaka 10, mankhwalawa amatupa. Kwa amuna, kukhazikitsidwa kwa mafuta mwachindunji mu urethra kumalimbikitsidwa.

Thupi glycyrrhizic acid lili mu Epigen kukonzekera, Glycirat. Malangizo ogwiritsira ntchito glycyrrhizic acid akuti motsutsana ndi momwe amathandizira, odwala matenda ashuga amayeneranso kupereka mavitamini ndi michere.

Kafukufuku athandizira kudziwa kapangidwe kake ndi kapangidwe ka glycyrrhizic acid, zidapezeka kuti mamolekyulu a zinthu ndi ofanana ndi mamolekyu a mahomoni opangidwa ndi adrenal cortex.

Kupeza kumeneku ndikuloleza kugwiritsa ntchito asidi mankhwala a mahomoni.

Milandu yama bongo osokoneza bongo, kusintha kosiyana, kuyanjana

Mpaka pano, palibe chidziwitso chokhudza kusokonezeka kwa thupi pogwiritsa ntchito mankhwalawa. Komabe, zovuta zomwe zimachitika mthupi zimadziwika, mwachitsanzo, zimatha kukhala totupa, kutupa, kuyabwa ndi kupendama. Zizindikiro zoterezi sizachilendo kusiyana ndi zochitika pafupipafupi.

Mankhwala okhala ndi glycyrrhizic acid kuphatikiza mankhwalawa samayenderana ndi maantibayotiki, antiseptics, painkillers ndi anti-kutupa, sangathe kuwayambitsa.

Kugwiritsa ntchito limodzi ndi othandizira ena kumatha kuyambitsa zotsatira zoyipa.

Tikulankhula za mapiritsi ndi mankhwala osokoneza bongo, fanizo lawo:

Kuti mumve zambiri za momwe mungagawire, chonde werengani buku lothandizira kugwiritsa ntchito mankhwalawa.

Kwa nthawi yamankhwala, wodwalayo ayenera kutsatira zakudya zopatsa thanzi, kudya mavitamini ndi kukonzekera mchere. Monga ndemanga za odwala zikuwonetsa, kugwiritsa ntchito chinthu sikunakhudze thanzi lawo, zovuta sizimabwera.

Kugwiritsidwa ntchito kosalekeza kwa glycyrrhizinate ngati zotsekemera kumayambitsa kuyamwa kwa sodium ndi potaziyamu kuchokera m'thupi, zomwe sizovomerezeka komanso zodzala ndi zotsatira zowopsa za matenda a shuga.

Gwero la acid

Glycyrrhizic acid imatha kupezeka kuchokera ku licorice rhizomes. Chomera chimagwiritsidwa ntchito popanga mankhwala komanso kungopanga tiyi kuti athetse mavuto a metabolic. Kumwa koteroko kumathandizira kuchepetsa shuga m'magazi msanga, kumalimbana ndi matenda a virus, atherosulinosis yamitsempha yamagazi, komanso matenda oopsa.

Kupanga tiyi, muyenera kutenga kapu yamadzi otentha ndi magalamu khumi a chinthucho, ikani ziwiyazo mu madzi osamba, ndikugwiritsitsa kwa mphindi 15. Kenako chipangizocho chidzafunikira kukakamizidwa kwa ola lina, chinthu chotsirizidwa chimasefedwera kudzera mu chidebe, chimabweretsa ndi madzi owiritsa ku voliyumu yake yoyambirira. Imwani pang'ono m'magawo tsiku lonse, maphunziro ake ndi masiku 14.

Palinso Chinsinsi chopangira chakumwa china chothandiza, chomwe chingakhalenso ndi glycyrrhizic acid. Makatani a nyemba, elecampane, masamba a blueberry, muzu wa burdock, licorice, dandelion amatengedwa, osadulidwa ndi chopukusira khofi, kutsanulira supuni yosonkha ndi kapu ya madzi otentha ndikusiya kwa mphindi 25.

Ngati muthana ndi thanzi lanu mosamala, imwani zakumwa pafupipafupi, patapita kanthawi thupi ladzala ndi zinthu zofunikira, ndipo glycyrrhizic acid imayambitsa kuchuluka kwa shuga m'magazi, kulimbitsa chitetezo chokwanira komanso kukonza mkhalidwe wa wodwala wodwala matenda ashuga.

Zambiri pa zotsekemera zimaperekedwa mu kanema munkhaniyi.

Mtengo wa glycyrrhizic acid, komwe mugule

Gulani gel Kugonana kwa Epigen zotheka ma ruble a 723, botolo lokhala ndi 250 ml.

Mtengo wa mankhwala Phosphogliv ndi ma ruble 500 ma 500 makapisozi.

Maphunziro: Anamaliza maphunziro awo ku Rivne State Basic Medical College ndi digiri ku Pharmacy. Anamaliza maphunziro ake ku Vinnitsa State Medical University. M.I. Pirogov ndi gulu lozindikira kutengera izi.

Zokumana nazo: Kuyambira 2003 mpaka 2013, amagwira ntchito monga mfesi ya zamankhwala komanso manijala wa khemisi. Anapatsidwa makalata komanso kusiyanasiyana kwa zaka zambiri akugwira ntchito molimbika. Zolemba pamitu yachipatala zidasindikizidwa m'mabuku azofalitsa (manyuzipepala) komanso pazamasamba osiyanasiyana pa intaneti.

Ntchito zina

Mankhwala amathandizidwanso ngati othandizira, makamaka poyeserera kwambiri. Kuchiritsa glycyrrhizic acid, kugwiritsidwa ntchito komwe kumanenedwa pazodzikongoletsera pofuna kuchiritsa khungu ndi dermatitis, kumagwiritsidwa ntchito pozizira, mafuta odzola ndi ma tonics pakhungu lowoneka bwino.

Katunduyo amalimbikitsa kutseguka kwa madzi amchere amchere, kumayeretsa, kuyeretsa, ndikufewetsa komanso kukonzanso mkwiyo.

Ndi makhwala ati omwe sayenera kumwa?

- ndi corticosteroids (mankhwala "Licorice Tingafinye") sizingachitike. Zimatha kupereka zotsatirapo zabwino komanso zoyipa. Ndikwabwino kusakaniza mankhwala nthawi imodzi.

- ndi okodzetsa - zidzatengera kuwonongeka kwakukulu kwa potaziyamu.

- ndi njira zakulera za pakamwa - zimayambitsa mavuto.

Musanalandire chithandizo, muyenera kufunsa dokotala woyenerera yemwe akupatseni mtundu wodalirika komanso wowona.

Momwe mungagwiritsire ntchito?

Aerosol imapakidwa kumadera omwe akukhudzidwa kasanu ndi kamodzi patsiku. Kutalika kwa mankhwalawa kuli mpaka masiku khumi. Kirimuyo amatsukidwa kangapo patsiku.Makamaka pakugwiritsa ntchito nyini, pali nozzle wosavuta, womwe ndi chubu lalitali ndi nebulizer.

Musanagwiritse ntchito, muzitsuka ndi sopo ndi sopo. Mukatha kugwiritsa ntchito, ndikofunikira kugona pansi kwa mphindi zingapo kuti mankhwalawo amwe. Amuna amatha kubaya mankhwalawa mu urethra mtunda wa 1 cm.

Ndi matenda a papillomavirus ndi herpetic, mankhwalawa amawazidwa kumaliseche, komwe kumapangidwa maliseche ndi herpetic. Ngati patadutsa masiku asanu papillomas sanasoweke kwathunthu, amachotsedwa ndi kuwonongeka kwa mankhwala kapena thupi, ndiye kuti mankhwalawo amathandizidwanso.

Malinga ndi ndemanga za ogwiritsa ntchito, achire amawonedwa tsiku lachitatu atalandira chithandizo. Mitunduyi imasowa, ambiri amakhala athanzi, palibe vuto. Madokotala amalingaliranso kuti mankhwalawa ndi amodzi mwabwino kwambiri pazamankhwala.